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Various studies of implant
2001/2/4 per io-prostho seminars
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Topic
Immediate implant vs delayed
immediate implant )
Wide-diameter implant vs standard-diameter implant )
Single-stage vs Two-stage )
Immediate loading vs progressive
loading )
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Brnemark group traditional protocol
recommends a 12-mon th heal ing per iod
between tooth extraction and placement ofimplants.(Adell R et al 1981 In t J Oral Surg)
Preserve alveolar bone conceptimmediate implant concept
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Schulte(1984)
Tuebinger implant
Frial i t-2 imp lant
Stepped-tapered root
analog
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Immediate implant
Advantage
Preservation of the alveolar bone
Esthetic(extracted tooth has a desirable alignment)ideal implant position
natural scalloping and distinct papillae are easier
to achieve
maximal soft tissue support
Fewersurgicalinterventions
Reduction in treatment t ime & cost
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Immediate implant
Disadvantages
Misalignment of the extracted tooth may lead to
unfavorable angulation of the fixture
Stabilization may require more bone than is
available beyond the apex
Localized peri-implant bone defect Primary soft tissue closure
( submerged vs transmucosal implant)
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Indication for Immediate implant
Root fracture
Trauma not affecting the alveolar he
alveolar bone
Decay without purulence
Endodontic failure
Severe periodontal bone loss
Residual root
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Contraindication for Immediate
implant
Presence of pus
Lack of bone beyond the apex or close
relationship to the anatomical vitalstructures
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Extraction site defects
Residual defect
morphology and the
regenerative potential at
the extraction sites
Salama H & Salama M
1993 IJPRD
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Extraction site defects
Type I ideal site for immediate implant
4-/3-wall socket with minimal bone
resorption (
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Extraction site defects
Type II need orthodontic extrusion
Dehiscence > 5mm
Substantial discrepancy between the
fixture head & neck of the adjacent teeth
Significant gingival recession or esthetics .
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Extraction site defects
Type III not suitable for immediate
implant
inadequate vertical &B-L bone dimension
Recession and severe loss of labial bone
Severe circumferential and angular defect
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The decision to submergeshould base onthe following factors
Plaque control Smoking
Periodontal conditions
The degree of stability The presence of provisional removable
denture
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Submerged implant
Primary closure
Bowers & Donahue(1988)
Edel (1995) ,Chen & Dahlin(1996)
Rosenquist(1997)
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Rotated palatal flap for
immediate implant
Nemcovsky CE
2000 COIR
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Transmucosal immediate implant
Cochran & Douglas(1993);Brgger et al (1993)
Schultz(1993) ;Lang(1994)
Brgger et al (1996);Hmmerle et al (1998)
Evidences emphasize the importance of
in fect ion con tro lfor a successful tx. of
outcome following immediate implant oftransmucosal implants
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Transmucosal immediate implant
Original peri-implant defectwas the
most critical factor relating to the final
amount of bone-to-implant contact Horizontal defect dimensions of >4mm
resulted in a lower bone-to implant
contact than dimension of 1.5mm or lessWilson et al 1998 JOMI
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Conclusion about immediate
implants
There is no consensus regarding aboutthe need for gap filling and the best graft
materials The use of membrane does not imply
better results on the contray ,membraneexposure may carry complications
The absolute need for primary closure
Schwartz-A rad D et al 1997
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Immediate vs non-immediate
implantation for full-arch fixed
reconstruction following extraction of allresidual teeth : A retrospective comparative
study
Schwartz-A rad D et al 2000 JP
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Results
5-year cumulative survival rate(CSR)
Immediate implant (96%) non-immediate(89.4%)
Mean potential contact area(PCSA) 230mm2
Significant differences in CSR in maxilla(96.6%
vs 82.9%)
Posterior Max.Immediate imp lant (100%) non-immediate(72%)
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Conclusions
Survival rates of implants placed to support full-arch
ceramo-metal prosthesis can be ranked as follows :
bone qual ity , immediate implant,PCSA Immediate implantation exerts its effect through
higher PCSA values by a compensatory effectfor
bone quality
Immediate implant does not carry additionalmorbidity
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Spontaneous in situ
gingival augmentation
Bu rton Langer
IJPRD 1994;14:525-535
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Delayed immediate implant
Alveolar bone changes during the healingperiod
Strong tendency for the defects to f i l l- inin thehorizontal plan and bone growth to occur in thevertical plane of the height of the cover screw .
Good shor t -term prognos is w i th bone
regenerat ionoccurring around the defectwithout the use of barrier membranes or bonesubstitutes
Nir -Hadar O et al (1998)
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After an average follow-up of 12.4 months, peri-implant pocket depth , the ging ival index, the
hygienic index, and the degree of bone
resorpt ionwere examined. A life-tableapproach (Kaplan-Meier) was applied forstatistical analysis, and showed no differencebetween primary and secondary immediateimplants. Also, none of the parameters
examined demonstrated a statisticallysignificant difference between the twogroups.
Mensdor ff-Pouil ly et al 1994 JOMI
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However, compared with the groups of
secondary immediate implants, the group of
primary immediate implants showed atendency towards deeper pocket formation
and an increased frequency of membrane
dehiscencesthat may be due to the poorer
quality of the soft tissue covering.Mensdor ff-Pou il ly et al 1994 JOMI
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3-year Prospective Multicenter
Follow-up
No clinical difference with respect to socketdepth or when comparing the differentplacement methods.
Higher failure rate was found for short implantsin the posterior region of maxilla .(extracted forperiodontitis)
Mean marginal bone resorption : (from loadingto 1yr F/U) Max.(0.8mm),mand(0.5mm)
Implant survival : Max(92.4%);Mand(94.7%)
Grunder U et al 1999 JOMI
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Generally,
primary immediate implant
max. anterior
secondary immediate implant
mandible,posterior maxilla
Mensdorff-Pou il ly et al 1994 JOMI
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Thanks for your attention!!
E id f i i f
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Evidence for osseointegration of
immediate implant
Experimental animal studies (Kohal et al
1997)
Controlled human studies(Palmer et al1994)
E id f i t ti f
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Evidence for osseointegration of
immediate implant
Root-analogue titanium implants
Lundgren et al (1992) beagles dog study
Kohal et al(1997) monkeys
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E id f i t ti f
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Evidence for osseointegration of
immediate implant
Clinical studies
Becker et al(1998) prospective clinical
human trials of 47 immediate implantswithout bone augmentation
cumulative success rate of 93% followed
between 4 to 5 years
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Bone augmentation in combination
with immediate implant
GBR-barrier membranes
Experimental animal studies
Dahlin(1989)rabbits
Becker et al (1991) barriers enhance
predictability of bone fill in immediate
extraction sockets when compared with
a mucoperiosteal flap
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Bone augmentation in combination
with immediate implant
GBR-barrier membranes
e-PTFE membrane
Lazarra(1989)
Becker &Becker(1990)
Nyman(1991)
Hammerle(1998)
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Bone augmentation in combination
with immediate implant
GBR-barrier membranes
e-PTFE membrane
Becker (1994) 49 immediate implantwith e-PTFE alone
--- 93.6% bone fill ,1-year functional
loading success rate 93.9%
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Bone augmentation in combination
with immediate implant
GBR-barrier membranes
Collagen membrane( Cosci&Cosci 1997)
polyglactin (balshi 1991)
Polylactic acid (Lundgren 1994)
Fascia lata (Callen & Rohrer 1993)
Autogenous gingival grafts(Evian & Cutler
1994)
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Barrier membrane exposure
Compromised results
Simion (1994) bone fill (97% vs 42%)
Augthun(1995) Successful bone regeneration & complete bone
filling ,but strict infection control is followed
Mellonig (1993)
Shanaman(1994)
Rominger & Triplett (1994) 96.8%
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GBR and bone grafts
DFDBA ( negative )
animal study
Becker (1992) dogs study
Becker (1995) dogs study
Kohal(1998) dogs study
Clinical study
Gelb(1993)
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GBR and bone grafts
DFDBA ( positive )
Callan (1990)
Mellonig (1993)
Landsberg (1994) combined with Tc
Gher (1994)
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GBR and bone grafts
Hydroxyapatite
Wachtel et al (1991) biopsies taken on
3M showed enhanced bone regeneration
than non-grafted sites.
Knox (1993)
Novaes & Novaes (1993)
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Compromised sites infection
Pecora(1996)
32 teeth due to root fx.,perforation,endo-
perio complication ,F/u 16M Rosenquist & Grenthe(1996)
periodontal disease (92%)
trauma,root fx.,endodontic failure (95%)
Novaes(1995,1998)
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Compromised sites infection
Immediate implantation at chronically
infected sites may be successful,the
extent of the defect ,the implant primarystability,and esthetic consideration of
future restoration must be considered.
Biologically active bone
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Biologically active bone-
differentiating substances
Cook (1995) recombinant human
osteogenic protein-1(rhOP-1)
Cochran et al(1997) recombinant humanbone morphogenetic protein-2(rhBMP-2)
Hedner & Linde(1995) membrane + BMP
compromised blood supply
Future about biologically active
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Future about biologically active
bone-differentiating substances
Identification of the ideal carrier substrate
Dose application
The effect of combination
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Late implants
A period of >6 months for healing of the
extraction site is recommendation prior to
implant placement