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Responsibility to Science What If... 2009 Global Citizenship Report
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Responsibility to Science

What If...2009 Global Citizenship Report

p. 12

Responsibility to Science

p. 10

Overview: Responsibility to

Global Citizenship

p. 22

Responsibility to Ethics

Contents

p. 7

p. 9

Letter from Greg Lucier, Chairman and Chief Executive Officer

Letter from Cristina Amorim, Vice President of Global EHS and Citizenship

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p. 28

Responsibility to People

p. 44

Responsibility to the Environment

p. 56

Responsibility to Community

p. 65

p. 66

p. 68

Awards and Recognition

Data Summary table

Appendix A: GRI Index

About Life Technologies

Life Technologies Corporation (NASDAQ: LIFE)

Life Technologies is a global biotechnology tools company

providing premier systems, consumables, and services for

scientific researchers around the world.

Life Technologies, headquartered in Carlsbad, California, is

the result of the combination of Invitrogen Corporation and

Applied Biosystems Inc. in November of 2008, and the

company continues to serve its customers under those two

well-known brands. Invitrogen is the premier provider of

reagents and consumables that are usable across multiple

platforms, while Applied Biosystems remains the top provider

of systems-based, end-to-end solutions in areas such as PCR

and genetic sequencing.

With more than 50,000 products used by more than 75,000

customers around the globe, Life Technologies is advancing

scientific research in areas such as academic research, drug

discovery and development, toxicology and forensics, disease

diagnostics, clinical cell therapy and regenerative medicine,

and biologics manufacturing.

The company had sales of more than $3.3 billion in 2009,

employs a workforce of approximately 9,000 people in

more than 160 countries, and possesses a rapidly growing

intellectual property estate of approximately 3,900 patents

and exclusive licenses.

At Life Technologies, our goal is to make scientific research

and application easier, faster, and more reliable, so we can

make life even better.

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Patents and exclusive licenses: 3,900

Facilities: 82 sites

Employees: ~9,000 people

Employee hires: 1,253

Net sales: $3.3 billionProduct types:

50,000+

R&D investment: $300 million+

2009 in Review

Presence: 160 countries

to be a great company, we must also do good. We must be dedicated to unyielding ethics, sustainable business practices and giving back to our communities. In the following pages, you will read about how we have made global citizenship not only an integral part of our business, but also a passion for our employees.

Some of the most exciting developments we will highlight in this report:

• Partnering with J. Craig Venter, an internationally renowned thought leader in the field of genomics, in his quest to mine the microbes of the deepest oceans for possible solutions to mitigate climate change.

• Outfitting Haitian officials through DnA-Prokids with 21st-century forensics tools to assist in the reunification of families and children separated during the aftermath of the earthquake in early 2010.

• being not only an employer but also a customer of choice for a growing number of minority-owned and small business enterprises in the communities where we do business.

• Giving over $5 million in 2009 through our Life technologies Foundation to organizations that promote scientific education and literacy among the general public.

• Creating an increasingly robust commitment to environmental responsibility, with a carbon management plan that will have us on track to reduce our footprint by 25% by 2012.

I am proud that our citizenship efforts have been recognized by leading organizations. Life technologies is a member of the FtSE4Good Index Series and the Dow Jones Sustainability Indexes, and most recently we were named to Corporate Responsibility Magazine’s 100 best Corporate Citizens List. In early 2010, we were also included in the bloomberg-Maplecroft Climate Innovation Index as one of the 100 top-performing companies on carbon management and environmental innovation.

In short, Life technologies values a culture that is deeply dedicated to the future of science, respects the environment, and is committed to doing the right thing. Global citizenship is not a destination, but a journey—one that Life technologies will undertake for years to come.

Greg LucierChairman and Chief Executive Officer

At Life Technologies, our mission is to shape biological discovery, thereby improving the human condition. As a scientific company, we primarily carry out this mission by enabling innovative life science research in hundreds of thousands of laboratories worldwide. We also believe that a commitment to global citizenship is an equally important way for Life Technologies to play a role in bettering life for all of us.

Letter from the Chief Executive Officer

Investment in innovation: $2 million

Volunteer hours: 15,798

Water saved: 138,064 m3

LEED buildings: 3

Safety Committee members:

521

Reduction in energy consumption:

6%

Employee completion rate for

ethics training: 98%

Gender diversity: 43% women

External collaborations: 20 collaborations,

$1 million investment

2009 in Review

Our citizenship efforts are focused on five key areas where our business can have meaningful impact: science, ethics, people, environment and community. In each of these areas, we identify opportunities, set goals, establish metrics, and monitor progress.

In the pages of this document, you will find a more robust and data-rich report than we provided last year, owning to our decision to report within the framework of the Global Reporting Initiative Generation 3 (GRI G3) guidelines. It is an ambitious undertaking that requires us to expand the transparency of what we measure, the progress we’ve made, and the challenges we face. You will also meet some of the people at Life technologies. Following are some highlights from 2009:

• Fostered 20 external collaborations and invested more than $300 million in R&D to address some of the most pressing issues of the 21st century—scarcity of natural resources, water and food security, intractability of certain diseases, and biodiversity loss.

• Initiated eco-efficiency conservation projects that resulted in reductions of 6% in energy use, 5% in CO2 emissions, and 19% in water intake—delivering over $4 million in free cash flow to the business.

• Introduced new programs in safety, health, and wellness to bring long-term prosperity to our company through the people who work here—reducing our injury/illness and lost time rates by 38% and 14%, respectively.

• Donated time, talent, and resources in all of the communities where we work and live, with nearly 16,000 volunteer hours.

• Implemented a new User-Centered Innovation program to increase the productivity of our business. Supported by a more than $2 million investment, innovation projects go beyond new product development, encompassing employee benefit offerings, internal and external social media, and cold chain packaging reduction.

We are proud of the work we do and recognize that there is yet tremendous opportunity ahead to go one step further. thank you for taking the time to review our progress on our journey, and we look forward to seeing you again in 2010.

Cristina AmorimVP, Global Environmental Health & Safety and Citizenship

Letter from the Vice President, Global Environmental Health & Safety and Citizenship

At Life Technologies, serving both science and society is at the heart of our mission. We believe that for our business to revolutionize science and return value to our shareholders, we must balance environmental and social issues. We have learned that living as global citizens not only differentiates our business and contributes to customer satisfaction, but also drives operational efficiency.

Responsibility to Global Citizenship

ScienceWe shape discoveries in molecular and regenerative medicine that will likely lead to cures for diseases such as cancer and heart disease. We also develop life science tools that enable safe and clean water supplies and a more abundant food supply.

EthicsLife Technologies is providing tools and technologies that help scientists explore not only the origins of life but also how they can be recreated and reproduced to cure devastating diseases, as well as pioneering work in uncharted territories to recapture biodiversity loss. This work requires high standards of ethical conduct and accountability.

Living as a responsible global citizen is one of our core values at Life technologies. Our systems, products, and services enable researchers to accelerate scientific exploration, driving to discoveries and developments that make life even better, all while minimizing our collective footprint. Our sustainability approach is to drive top- and bottom-line impact while addressing key challenges of the 21st century.

Science

Ethics

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PeopleWe recognize that the work we do attracts passionate and committed people, and we strive to be an employer of choice by creating a place where employees can thrive. We make teamwork, diversity, safety, health, wellness, and trust our priorities.

EnvironmentJust as we are committed to being one step ahead in scientific discovery, we are equally committed to going beyond protecting the environment to restoring the natural world.

CommunityLife Technologies defines community broadly—from the regions where we live, work, and operate to the community of scientists, researchers, and educators who use the products and services we provide.

People

Environment

Community

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we could cure disease, alleviate hunger and poverty, eliminate pollution, and create renewable and clean sources of energy?

What if...

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Genomics holds immense promise for unraveling the causes of disease, developing better medical diagnostics, and understanding how animals adapt to climate change. the ability to sequence an entire genome at lower cost will enable fundamental changes in how we identify and treat disease, mitigate pollution, address species extinction, ensure clean water and healthy food for the global community, and enhance our ability to combat crime and terrorism.

FOSTERING AN ERA OF PERSONALIZED MEDICINE Imagine receiving a cancer diagnosis, and with it a laboratory report that identifies the biological makeup of your cancer, as well as a drug therapy regimen that is designed specifically to attack that cancer and repair your body. Robust sequencing capabilities are critical to the advancement of personalized medicine, as the treatment of disease shifts to therapies that are specific to an individual’s unique genetic makeup.

In 2009, Life technologies introduced the SOLiD™ 3 System, the latest in a quickly evolving instrument line for genomic sequencing that is to genomics what the laptop was to a mainframe computer—smaller, faster, and more adaptable. the SOLiD™ 3 System enables scientists to sequence a human genome for less than $10,000, with a roadmap that will increasingly drive capabilities toward the $1,000 genome milestone. With instruments that unlock the secrets of our DnA, and products and services that advance the promise of regenerative science, we are helping usher in an era of personalized medicine.

• Researchers at translational Genomics Research Institute (tGen) have partnered with Life technologies to translate scientific discoveries at the genetic level into knowledge about the underlying causes of disease. the alliance enables tGen researchers to apply best-of-breed sequencing technology across a broad spectrum of research efforts that focus on developing a more personalized approach to medicine. this approach represents a potential clinical shift from treatment of disease based on symptoms, to therapy that is specific to an individual’s unique genetic makeup. Among the goals of this project is to advance the promise of personalized medicine by reducing the cost of genome sequencing to make it a routine tool in medical care.

• Researchers at the Mayo Clinic are using the SOLiD™ 3 System to generate data to better evaluate possible advantages of sequencing-based approaches to assist in evaluation of potential biomarkers in head and neck cancer—genetic variations that may ultimately reveal the underlying mechanism of cancer development so that it might one day be preventable.

Responsibility to Science

It’s a bold vision, but one that’s being brought closer to fruition every day in labs across the globe. Scientists are accelerating progress toward these goals, armed with tools from Life Technologies.

Responsibility to Science

SyNThETIC BIOLOGy: EMERGING SCIENCEthe living world provides extraordinarily rich yet largely unexplored mechanisms for understanding how nature controls and processes information, materials, and energy. Learning how to effectively harness the power of the living world and replicate its systems is what synthetic biology is all about. It has the potential to help us solve complex challenges like species preservation and biodiversity, develop new vaccines and drug therapies, create biofuels from plants, optimize the food supply, and improve bioremediation—the bio-engineering of organisms to attack waste or pollution in water or soil.

In 2009, Life technologies began exploring synthetic biology as part of a business that would include various technologies, some already in our portfolio and others that will be developed or acquired. We already sell Vector ntI®, one of the most widely used software packages for molecular biology in the world. It is used by researchers for molecular cloning, sequence analysis, data management, vector selection, and design of expression constructs. We help our customers leverage this software platform to develop new applications for synthetic biology. With greater investment in synthetic biology, Life technologies is supporting accelerated research into solutions for the pressing problems of the 21st century.

What Would you Do With a $10,000 Genome?In order to inspire new scientific approaches that employ advanced genomic technologies, Life Technologies created a “What Would You Do With a $10,000 Genome?” grant program in 2009. During the 10th annual Advances in Genome Biology and Technology meeting, Dr. Charles Mullighan, MD, PhD, of St. Jude Children’s Research Hospital was awarded the inaugural prize.

Dr. Mullighan was selected from more than 200 entries, based on his interest in using a next-generation sequencing approach to conduct research to assist in the development of potential new therapies to treat acute lymphoblastic leukemia, a cancer of white blood cells that affects one in 29,000 children each year. Dr. Mullighan proposed to use the SOLiD™ 3 System to conduct research to explore potential new treatment options for the 15 percent of children who relapse each year, of whom only 30 percent will survive five years.

Life Technologies enables the development of next-generation commercial biofuel crops—such as the Jatropha.

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ENABLING SCIENTIFIC ADVANCEMENT One of the world’s foremost researchers in synthetic biology is Life technologies research partner J. Craig Venter, PhD, a biologist and entrepreneur who is working to create synthetic organisms and to document genetic diversity deep in the world’s oceans. In 2009, the J. Craig Venter Institute (JCVI) launched a new Sorcerer II Expedition—the J. Robert beyster and Life technologies Foundation 2009–2010 Research Voyage, a two-year trip to expand understanding of how microbes might be used in the fight against climate change.

His previous work includes research into organisms that can turn CO2 into methane, which could be used to make fuel from the exhaust of power stations, and another that turns coal into natural gas, speeding up a natural process and reducing both the energy needed to extract the coal and the amount of pollution released when it is burned.

Venter’s latest endeavor is to explore the possibility of using sunlight to convert algae into biofuel. Algae are a desirable resource because they live in areas not useful for producing food and do not need clean or even fresh water. they also use far less space to grow than traditional biofuel crops such as corn or palm.

Preserving Biodiversity: Cheetah Conservation in NamibiaCheetahs are a unique breed of cat. Approximately 99 percent of their genes are identical, a biologically significant fact given that in most mammalian species only 80 percent of the genes in related individuals are identical. This lack of variation compromises the big cat’s ability to adjust to sudden environmental changes. Thus, cheetahs are highly susceptible to certain viruses and reproductive health problems. Today, only 10,000 wild cheetahs exist globally.

The middle of African bush country might seem like an unlikely place for a high-tech DNA laboratory, but with 20 percent of the world’s free-ranging cheetah population living in Namibia, it’s the perfect place to develop the tools needed to save this endangered population. In 2009, we invested in the founding of the Applied Biosystems Genetic Conservation Laboratory, located at the headquarters of the Cheetah Conservation Fund (CCF) in Otjiwarongo, Namibia. Here, four scientists and 50 international course participants have been trained on advanced genomic analysis technology and have developed a noninvasive

genetic monitoring program, using Life Technologies genetic analysis systems and reagents as tools in their work to accurately characterize the population of cheetahs in Namibia and other home-range countries. Scientists are not only tracking the cats but are working to answer questions such as how cheetah genes transfer from one population to another, in order to identify geographical patterns of genetic variation and to study the animals’ behavior in specific habitats. This partnership is designed to further our knowledge of biodiversity on a larger scale, with a goal of giving us the knowledge we need to reverse negative trends in species loss.

Life Technologies’ tools and technologies enable the development of biofuels, carbon biosequestration, and bioremediation.

Responsibility to Science

SPONSORING CLEAN WATER, SAFE FOOD SUPPLIESClean water and an abundant food supply may seem to be only emerging-world concerns, but as we have learned recently, with Salmonella and E. coli scares in lettuce and peanut butter in the U.S., a safe food supply is truly a global issue. the life sciences are emerging as a critical player in the quest to end hunger, alleviate poverty, and reduce water- and foodborne illness.

In April of 2009, we expanded our portfolio of food safety testing solutions with new kits and software aimed at improving detection of Salmonella and Listeria monocytogenes in food. by June, those kits were in widespread use and becoming certified through the Emergency Response Validation

Reuniting FamiliesIn addition to a significant financial contribution from its Foundation, Life Technologies deployed the most innovative instrumentation to DNA-Prokids for the reunification project in Haiti.The DNA-Prokids program enables Haitian officials to take samples of genetic data from 6,000 adults who have reported missing children, from immediate relatives with a blood

relationship, and from children with no family or doubtful relatives. The aim is to help reunite abducted and homeless children with their parents after the devastating earthquake.

program of the AOAC Research Institute, one of the world’s leading food industry standards organizations, in response to the outbreak of Salmonella contamination in the U.S. peanut butter supply.

Across the globe, the Korean government is utilizing Life technologies genetic analysis tools to trace the origin of beef

crossing their borders, in an effort to address problems with contamination in imported beef products. Armed with this vital information, animal disease control is not limited to quarantines and inspection, but is a proactive process that helps protect the Korean population from contaminated meat.

Life Technologies provides the tools needed to develop new ways of feeding an ever growing population.

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ADVANCING FORENSICS AND hUMAN IDENTIFICATION An indescribable sense of personal violation occurs when someone becomes a victim of crime. For this reason, crime and its impact on society has been of primary concern for many countries throughout the world, regardless of culture or geography. today, largely due to DnA testing, victims are more likely to see the perpetrators held accountable for the crimes they’ve committed. the use of DnA, combined with secure databases, has revolutionized the investigative process, making DnA an advanced crime-fighting tool for convicting the guilty and exonerating the innocent.

Life technologies offers the most advanced DnA testing systems available in the world; they’re used by forensic

laboratories every day to solve crimes. In recent years, Life technologies has made significant advancements and technology improvements that have enabled smaller amounts of DnA to

“What makes Life technologies and our industry particularly exciting is that we can meaningfully contribute to improving the human condition by the work that we do over an extended period of time. I see the [Haiti earthquake] relief fund as an opportunity to act upon that same aspiration today …” —Nicolas Barthelemy, President of the Cell Systems Division, Life Technologies

be obtained or more complex types of samples to yield an answer. As a result, a broader range of crime investigations can benefit from DnA technology.

Property CrimesProperty crimes include breaking and entering and theft. Although property crime investigations have not typically utilized the power of DnA testing, a recent study completed by the Denver Crime Laboratory is powerful testimony to why DnA should be used. the Denver Crime Laboratory reported they were able to reduce property crimes by more than 30 percent, saving more than $5 million in police costs and preventing an estimated $36.8 million of property loss over the past three years. As a result, the laboratory now routinely processes property crimes using DnA technology.

Our forensic kits enable the utilization of forensic evidence in criminal investigations.

Responsibility to Science

PREPARING FOR ThE ExPANSION OF DNA DATABASING Law enforcement agencies from the United States to Europe, China, and throughout the Middle East are now implementing DnA databases to assist with criminal investigative processes, helping to bring justice to victims around the world.

Once DnA database legislation is enacted, Life technologies provides guidance on implementing world-class DnA testing systems, creating a streamlined workflow for high-throughput processing of DnA samples.

African BushmenOne global challenge for the pharmaceutical community is to develop drugs that are effective for individual populations. Life Technologies aids in this endeavor; a breakthrough in South Africa has revealed new and surprising diversity within the human genome, and demonstrated how interconnected individuals are to one another.

A Southern African bushmen collaborative project involved the whole-genome sequencing of two named individuals: !Gubi, a Kalahari bushman, and Archbishop Desmond Tutu. This project had some surprising results.

• It established a new benchmark in the level of diversity within the human genome. the Kalahari bushmen live near what is thought to be the epicenter of ancestors to modern humans. Due to this physical proximity, we observe a high level of diversity between their genomes. For example, we saw more diversity between two bushmen who live about 1,000 miles apart than is seen between a Caucasian and an Asian.

• Archbishop tutu’s genome was sequenced on the premise that his ancestors belonged to two of the major groups within the bantu population. Instead, the study

uncovered that somewhere in Archbishop tutu’s lineage, on his maternal side, there was an African bushwoman, proving that Archbishop tutu is distantly and directly related to the Kalahari bushmen.

By characterizing the genetic variations that are present in Southern African genomes, better drugs (such as anti-viral drugs for HIV) can be generated that are useful for specific populations. This project represents an important first step toward this goal.

DNA testing and databasing around the world is rapidly expanding.

• More than 75 countries currently have or are in the process of establishing DnA databases to combat crime. Life technologies provides technical support and forensic testing expertise to all of these countries as they establish these systems.

• this year the government of Japan standardized DnA collection and analysis for the country’s 47 prefecture laboratories, using Life technologies DnA testing systems. Life technologies provides support to the national Police Agency and installed the most automated, sophisticated DnA testing systems, from DnA extraction through DnA analysis, creating a three-fold increase in sample throughput.

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Through an identification and tracking system, Life Technologies hopes to discourage the trafficking of human beings.

USING DNA TO COMBAT hUMAN TRAFFICkINGInterpol and other police organizations estimate that between 600,000 and 800,000 people—80 percent of them women and 50 percent minors—are taken by coercion or abduction each year for forced labor, sexual exploitation, illicit adoption, forced organ removal, recruitment as child soldiers, and other illegal purposes. Using DnA technology to reunite parents with children who have been abducted and recovered offers new hope for countless victims worldwide.

While human trafficking is a significant global problem, early 2010 brought a renewed sense of urgency to the need to reunite families when the devastating earthquake struck in Haiti. Life technologies and DnA-Prokids

recognized the need to use DnA in this situation and provided assistance.

• the Life technologies Foundation provided a grant in 2009–2010 to support DnA-Prokids, a nonprofit organization that uses DnA testing to deter the trafficking of children throughout the world, and to ultimately reunite parents with children by establishing the identity of a person who offers a child for adoption as the natural parent.

• the Foundation provided DnA-Prokids with instruments and reagents through a grant process and technical resources. the program is providing support to the Haitian government to process more than 5,000 samples.

Responsibility to Science

INNOVATING FOR CORPORATE ACCELERATIONIt might seem counterintuitive to focus on innovation outside the confines of the R&D department, but at Life technologies, innovation is not only about scientific discovery— it’s about improvement in all areas of the organization.

Since 2004, Life technologies has been using human-centered design methodologies in key areas of new product development. In 2009, we formalized these processes and began implementing them in other parts of the organization. this process, called User-Centered Innovation (UCI), is a methodology for developing and refining

products and services that blend the user experience with technology and product functionality. After a period of observation and inquiry of users, rapid prototyping gives way to an accelerated solution-development phase. It’s a novel approach that is creating a culture of innovators at Life technologies, and it is applicable to every function at the company. UCI has been applied throughout the company, in product development, It, HR, and packaging, and is providing rapid acceleration of corporate innovation. A successful UCI project, dubbed Project Edison, is a great case study for the approach.

User-Centered Innovation expands innovation to all parts of our organization.

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ADVANCING SCIENCE AT LIFE TEChNOLOGIESAs a global company with 1,350 scientists working in R&D in three divisions around the world, Life technologies recognizes the importance of creating mechanisms that allow researchers to cross the divisional boundaries of the company to share technology and information. In 2009, Science@Life was introduced to provide a framework for both internal and external connectivity—a forum for sparking innovation.

the capstone of internal connectivity was a Science and technology Symposium—the way for scientists to share their work with their peers. Held in October of 2009, 275 employees from around

the world came together for plenaries, guest lectures, poster presentations, oral sessions, and brainstorming workshops. Immediate synergies between products, technologies, and investigators emerged, with new products already launching in 2010.

External connectivity is focused around opportunities to better connect and partner with our customers. With that in mind, we created a $1 million pool of research dollars earmarked for Collaborative Research Compacts (CRCs). Each year, the company sponsors 20–25 collaboration projects that allow Life technologies researchers to connect with external thought leaders and forge relationships that last long after the six-month compact ends. In 2009, 87

proposals were received, and 20 projects were funded. We also hosted interns, with Science@Life funding 32 positions that are shared across divisions, providing a constant pool of young scientists and an ongoing dialog with top universities and research institutes.

Project EdisonThe market for real-time PCR instruments and reagents is a relatively mature one where Life Technologies already holds a substantial position. In 2009, the challenge was growing this market by redefining how we think about our customers, our business, and how we work together.

Using the UCI process and starting with observing the products’ users, the team learned that customers need more than innovative products—they need a “great colleague in the lab” to guide them in the use of technology.

As they learn and use the technology, their needs evolve and change.

The need for connection is greatest for researchers who are just learning the technology and looking for guidance. It drops off with intermediate users, who are fairly confident and need only residual support, and rises again for experts who want to share their knowledge with others and collaborate. These findings did not always correlate to the way Life Technologies had interacted with researchers. Our practices were not evolving with our customers’ needs.

The project team created a model of contact and connection that would best fit the user’s level of expertise. This was achieved using a web-based tool for researchers so they could easily find necessary information to plan and troubleshoot experiments based on their experience level.

While these concepts are still being tested and refined, feedback from users during prototyping has been very positive.

Science@Life is a comprehensive set of programs and initiatives investing in our R&D employees.

What if... we had the tools to reengineer certain forms of life? how would we anticipate the ethical, economic, environmental, legal, and social issues that might arise?

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Integrity and a solid moral compass are essential to the work of Life Technologies, and provide the basis for our comprehensive commitment to governance, ethical and lawful conduct, and transparency in our role as a global citizen.

being a responsible company means conducting business with the highest level of integrity. to truly achieve success, we must be known not just for being a great company, but also for being a good one—a company that is responsible and ethical in its actions.

CORPORATE GOVERNANCEOur ethical commitment begins with Life technologies employees, managers, and officers who conduct business under the direction of the Chief Executive Officer (CEO) and the oversight of the board of Directors to enhance the long-term value of the company for our shareholders.

the board is invested with the responsibility to oversee management and to assure that the long-term interests of the shareholders are served. both the board of Directors and management recognize that the long-term interests of shareholders are advanced by responsibly addressing the concerns of all shareholders and interested parties, including employees, customers, suppliers, the communities where Life technologies does business, governments, and the public at large.

More information on our corporate governance program is available at www.lifetechnologies.com.

EThICAL CONDUCTAdvances in science—particularly those in the areas of biology and medicine—can sometimes lead to ethical controversy. As a result, Life technologies places a high priority on scientific integrity and ethical conduct.

the Protocol is our guide to integrity. this document, updated biannually, governs our business practices and compliance efforts and provides specific examples of what constitutes acceptable and unacceptable behavior, consistent with our legal obligations, global values, and core business principles.

Life technologies requires annual training for all its employees regardless of job level, responsibilities, or geographical location. training is comprehensive and includes key laws and practices related to competition, insider trading, conflicts of interest, data integrity, the Foreign Corrupt Practices Act, environmental health and safety, intellectual property, human resources, appropriate business standards, and international business. In 2009, 98 percent of Life technologies employees completed the training; our goal is 100 percent successful completion.

Responsibility to Ethics

Responsibility to Ethics

RESPONDING TO EThICAL CONSIDERATIONSFor most U.S. companies with a global footprint, the Foreign Corrupt Practices Act (FCPA) is a key focus of governance. In general, the FCPA prohibits corrupt payments to foreign officials for the purpose of obtaining or keeping business. Lack of compliance is an ongoing problem in many areas of the world, and Life technologies is not immune.

the results of a 2009 internal audit recommended that Life technologies develop a new policy around the use of dealers. As a result, our legal, finance, and compliance teams worked together to complete a full analysis of all dealers and distributors with whom our company does business. With this information, the commercial operations

team was able to analyze dealer/distribution and corporate decisions. Life technologies now stands confident that our dealer/distribution networks are functioning in an appropriate manner.

Life technologies believes that respect for the dignity, rights, and ambitions of all people is a cornerstone of business excellence in the 21st century. When it comes to human rights, our policies describing labor conditions, fair compensation, working conditions, employee safety, and against child labor and forced or compulsory labor are clear and apply not only to our employees but also to the suppliers and contractors with whom we do business. We also have internal controls in place to prevent the release of customer information. to the best of our knowledge, there are no customer privacy complaints.

The Protocol is our guide to integrity and code of conduct.

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BIOEThICS COMMITTEEthe Life technologies bioethics Committee guides the responsible use of biotechnology to improve lives, accelerate scientific exploration, and protect our environment with a mixture of enthusiasm, caution, and humility.

the committee is charged with deliberating policy questions, communicating our positions on bioethical issues, and addressing issues such as stem cell research, cloning, use of genetic information, biological diversity, animal care, and related topics.

As synthetic biology emerges as an important area of practice for Life technologies, we developed a Synthetic biology Safety Committee in 2009 to address concerns and develop policy around ethical uses.

Life Technologies’ Commitment to IntegrityWe strive to create an atmosphere that supports the highest standards of ethics and integrity.

We expect honesty in all that we do and make decisions empirically, without bias.

We are committed to compliance with all applicable laws and regulations wherever we operate throughout the world.

We value our people and seek to provide an environment that encourages collaboration and teamwork, open

debate, honest communication, and individual achievement.

We require accountability and reward fairly and in accordance with performance.

We allow people to take risks, explore ideas, and find solutions.

We value cultural differences and believe that all employees are entitled to fair employment practices.

We seek to operate with mutual respect and trust, and without conflicts of interest.

We seek to conduct our business in a sustainable manner, aggressively protecting the environment and promoting the health and safety of our employees, our customers, and the citizens in the communities in which we operate; and engaging in sound, reliable business and financial practices.

We have a passion for improvement that infuses our compliance programs as well as the rest of our business.

Mark Stevenson, our President and Chief Operating Officer, chairs Life Technologies’ Bioethics Committee.

Responsibility to Ethics

EMERGING TOPICS IN BIOEThICSOur passion is to accelerate the discovery of how life works, through innovations in science and technology. As new research opportunities emerge, Life technologies is committed to ethically pursuing and upholding our promise of serving as responsible stewards in the global life science community.

Stem cell research has been shown to be a critical tool in the development of therapies to treat a variety of debilitating diseases, such as cancer, diabetes, and Alzheimer’s and Parkinson’s diseases. Life technologies supports stem cell research and has instituted strict ethical guidelines concerning the use of embryonic stem cells to ensure that all research is conducted in an ethically and scientifically responsible manner.

Genetic technologies, such as simple DnA tests, are becoming increasingly available to identify predispositions to disorders such as Huntington’s disease, cystic fibrosis, neurofibromatosis, and muscular dystrophy. this tremendous potential to diagnose and treat disease also carries a risk that personal genetic information may be used inappropriately. Life technologies is committed to protecting the genetic information of our employees. We have modeled our company policy after the United States Genetic Information nondiscrimination Act (GInA), which prohibits discrimination based on genetic information and restricts acquisition and disclosure of such information or health coverage–related consequences for having a genetic test or participating in research studies that examine genetic information.

Human embryonic stem cell research is one of the fastest-growing areas in cell biology.

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CONTRIBUTIONS TO PUBLIC POLICyFrom food safety efforts and R&D spending to tax changes, legislative activity directly impacts science and technology.

As a company committed to improving the human condition, Life technologies continues to shape policies that foster safe, effective, and beneficial products. We work with state, federal, and international legislative and regulatory bodies to advance public policy in areas such as:

• biomedical research funding and stem cell research

• Intellectual property policies that foster and reward innovation

• Regulatory and reimbursement frameworks that drive the onset of personalized medicine

• Alternative fuel policies

• DnA-based techniques for human identification, crime solving, and food safety

We also stay connected to public policy conversations by participating in a number of trade organizations and coalitions such as the biotechnology Industry Organization, the Personalized Medicine Coalition, and United for Medical Research.

Life technologies Corporation’s Employees Political Action Committee (PAC) is a separate segregated fund supported by voluntary financial

contributions from eligible employees. the PAC’s resources are used to support the campaigns of eligible candidates for public office. An employee-run board plans membership efforts and approves all contributions made from the PAC. the PAC is bipartisan and gives to candidates from both parties using published criteria. Contributions to and from the PAC are reported in accordance with Federal Election Commission guidelines.

In-Licensing/PatentsAt Life Technologies, we make the development of new intellectual property (IP) a central theme across our business. Each year we spend more than $300 million on research and development—more than any other life science tools company. This investment has resulted in a library of more than 3,900 patents.

We track new inventions closely; anyone can submit an invention disclosure at any time, and all submissions are reviewed. In fact, we recently implemented an online tool to enable an invention disclosure to be submitted and modified

across the company in a cumulative fashion. We believe that tracking the number of invention disclosures is a reasonable proxy for measuring innovation coming out of our R&D teams; we review our progress monthly.

We also provide performance incentives for innovation, and our R&D teams have specific goals and objectives designed around this metric. In 2009, we reworked our IP incentive effort so that inventors will benefit when their creation delivers real value for the company. Each year we invite key innovators to a dedicated Board of Directors dinner.

Our public policy deliberations include direct communications with policy makers and their staff.

you had a chance to be on the front lines of world-changing scientific developments?

What if...

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Our research tools are designed to enable scientific breakthroughs that can only be imagined today. At Life Technologies, we make a difference through a global group of dedicated employees looking for innovative ways to drive our vision of shaping discovery and improving life.

Our people are our greatest asset, and our investment in employees reflects our belief that global citizenship starts at home. Attracting and retaining the best talent is just the first step. Our priorities include assuring that our passionate and driven employees have the tools they need to do their jobs safely and efficiently, providing benefits that help create positive work/life integration, and staying engaged enough to know when we need to do something better or differently.

ATTRACTING TOP TALENTIn our ongoing endeavor to communicate to potential candidates how we strive to be an employer of choice, we launched a new recruiting campaign in 2009. We continue to embrace diversity in our recruiting efforts worldwide.

Life Even BetterAt Life technologies, we believe in the power of science to transform life and the power of people to make it happen. In 2009, we expanded our recruitment efforts to include the following key events and activities:

• An open house for Information technology candidates

• Participation in a Career Showcase at the University of California, San Diego

• A community networking event at the burnham Institute for Medical Research in La Jolla, California

• Sponsoring the San Diego Science Festival 2009, supporting the 2009 nifty Fifty lecture series, and enabling

scientists to teach in classrooms. the program was so popular that it has grown into the nifty One-Fifty for 2010.

• Sponsoring the Hood College Summer Science Research Institute, in support of research across a range of technologies, including bacterial expression of recombinant proteins and applications of liquid chromatography/mass spectrometry

• Expanding our global events and diversity outreach efforts

Talent Referral Program In 2009, we launched a new talent referral campaign to encourage employees to introduce great people they know to opportunities at Life technologies. the program was launched to reward employees for referring a successful candidate and included the option of donating an award to charity. this program continues to be a top priority for the talent Acquisition function, as approximately 15 percent of new hires come from employee referrals.

Responsibility to People

Responsibility to People

ONBOARDING INTO OUR CULTUREAcclimating new employees to the culture at Life technologies is a major initiative for 2010. Onboarding is an important foundation for ensuring success; in 2009 we identified aspects of the onboarding processes from Invitrogen and Applied biosystems that will be reengineered in 2010.

We’re looking at the success of the company’s Sales Development Program as a benchmark. this fast-paced program immerses new entry-level

sales representatives in a four-month training and development program and then deploys them with a defined product portfolio to support sales representatives at one of our key accounts. In 2009, we hired 19 associate sales representatives in 45 days. by the end of their training, the associates had contacted over 10,000 customers, logged 1,237 opportunities, and generated more than $816,000 in incremental revenue. they have now been deployed into the field.

Global Leadership MeetingTo kick off 2009, more than 250 members of the Life Technologies senior management team attended the two-day Global Leadership Meeting (GLM) in San Diego. The meeting’s theme, “The Power of One,” reflected not only the power of the combined Invitrogen and Applied Biosystems organization to shape scientific discovery and improve the quality of life, but also the power that each employee has to move the company toward its goals. This meeting was a chance for us to share our purpose, our values, and our plans for the upcoming year.

Each participant made a commitment to cascade the information and insights from the GLM to his or her team. Each and every Life Technologies employee should understand our overall purpose, goals, and objectives, and more importantly, how his or her work will contribute to our shared success.

In 2009, Life Technologies on-boarded 1,253 new employees.

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BenefitsLife technologies revamped its U.S. benefits offerings in 2009 to better meet the needs of our employees, and offered a new benefits package that includes comprehensive healthcare benefits, an employee assistance program, an employee stock purchase plan, and a 401(k) matching retirement plan. Unique to Life technologies’ benefits program is the navigenics Genetics Health Program. this program provides access to personal genetic testing that analyzes a participant’s DnA for risk markers that may genetically predispose him or her to various health conditions, including breast cancer, type 2 diabetes, colon cancer, and heart disease.

Additionally, we offer a number of supplemental benefits to help employees balance their work and life priorities,

including a transportation subsidy to promote carpooling and the use of public and alternative transportation.

RewardsAs Life technologies continues to evolve, it is important that we have a common and clear way to describe career paths, jobs, and rewards on a global basis. to support this, we introduced a consistent and transparent foundation for discussing and managing jobs, roles, skills, careers, and pay across the company. Every employee understands how his or her personal contribution relates to the overall success of the organization. Additionally, the new reward program promotes peer recognition by celebrating people whose work reflects their determination not only to go above and beyond in their work, but to embody our company’s values.

ENGAGING OUR PEOPLEWe know that our employees have to care for themselves before they can care for others. In 2009, we created a new employer brand framework for employees to easily understand both the tangible and intangible benefits of working at Life technologies. this framework includes benefits, rewards, opportunities to make an impact in the community and world, development programs, and networking opportunities that enable employees to take advantage of the options that will best support them in their drive to make life even better.

Responsibility to People

Developmentto empower employees to share in determining their career path, the new career framework also helps employees understand job requirements and potential opportunities.

We recognize the importance of development and performance conversations an employee can have with his or her manager. Life technologies therefore administers a formalized quarterly dialog process between each employee and his or her manager. In 2009, on-time execution of quarterly dialogs averaged 92.3

percent across the globe. this ongoing conversation is designed to address challenges and opportunities as they arise.

Additionally, Life technologies tracks engagement with a twice-yearly survey. While quarterly dialogs are useful in managing individual relationships, the survey is designed to help assess employee engagement and job satisfaction collectively. We believe the fast-moving culture of science and discovery has a great deal of influence on our culture, and by constantly monitoring engagement, we are able to

respond quickly and make changes as deemed necessary.

On both 2009 surveys, our employee engagement remained strong at 72 percent across the company. Our top employee engagement strengths included seeing a clear connection between individual jobs and company goals, feeling empowered to make a real impact at work, and enjoying good work relationships built on collaboration, openness, and respect.

Areas for improvement included career development and stress/pace of work,

Organizational effectiveness is enhanced though continual learning opportunities for our employees.At Life Technologies, our belief in the power of dialog shows up in our strong 72 percent employee engagement scores.

332009 GLObAL CItIzEnSHIP REPORt |

particularly with middle management. Given the recent merger and fast-paced integration priorities employees were balancing, these results were not surprising. the leadership team was inspired to continue efforts to help employees integrate their work and life, and more emphasis was placed on training and promoting a healthy workplace:

• A new training academy for employees in the operations area of the company was piloted in 2009, which emphasized expanded views of roles and responsibilities across

functions and divisions of the company. Classes in this program are designed and taught by senior leaders with expertise in a specific area of focus. Managers are encouraged to nominate employees for anywhere from one to 15 courses, with at least 10 required for graduation. three core academies were introduced in 2009: Supply Chain, Manufacturing, and Quality/Regulatory/EHS Academies. In its first year, the academy graduated a total of 179 employees from operations in Carlsbad, Foster City, and Pleasanton, California. In 2010, the program is being expanded to the rest of the global regions.

• A new leadership program was created to provide an opportunity for senior managers identified as emerging

leaders to experience what it would be like to run a company. through a simulation activity, participants learned how to make strategic business decisions; through this and other exercises, they acquired the knowledge and skills required to develop growth strategies, lead across the organization, gain a broad understanding of market influences, and develop processes that support innovation. In its pilot year, the program graduated 74 individuals.

by the Fall 2009 survey, we saw improvements on career-related items and modest gains/holds on items related to stress and pace. We will continue to drive company-wide efforts in these areas in the coming year.

Our Quest Survey monitors employee engagement.

Quest Survey

91% Participation

Spring 2009

Fall 2009

72% Engagement

93% Participation

72% Engagement

Responsibility to People

NetworkLife technologies recognizes the need for employees to build relationships and maintain open dialog with colleagues through professional networks and the greater community.

Life technologies has had an active IWIn (International Women’s Influential network) for several years. In 2006, this group identified the need for an internal mentor program to help with personal and professional development. With multiple global locations and several different generations of employees in the company, bridging the cultural and generational gap is important to driving strong working relationships.

User-Centered Innovation Drives a New Intranet SolutionLeveraging the power and effectiveness of social networking can be key in driving better connection, communication, and collaboration at Life Technologies.

Initially, the IT team was charged with building a new intranet solution that would help Life Technologies employees—by giving them relevant information and enabling them to share and network through the latest in Web 2.0 technology. We interviewed software firms, brainstormed ideas on

how the intranet should be constructed, set up committees, and spent months planning a solution…but were we just creating another solution like the previous one? User-Centered Innovation helped us change the paradigm.

Instead of designing what we thought our employees wanted, we asked them. Three key “wants” emerged: employees want to connect, communicate, and collaborate. The resulting discovery process led us to determine that a social networking site—one that takes the best of social media and tailors it

to Life Technologies’ culture—would best meet all of the needs. As a result of the work completed in 2009, a new internal social networking platform will launch later in 2010.

IWIN is an organization designed to support, mentor, and inspire our employees.

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to help facilitate this, the company’s internal mentor program launched a more sophisticated online matching tool that allows employees to pair with potential mentors across functions and sites. Importantly, this program provides employees historically viewed as minorities a chance to be mentored and develop their skills. the online program was launched in north America in 2009 and will expand to Europe and Asia Pacific later in 2010. Membership has increased from one chapter with 50 mentor pairs in 2007 to 21 chapters with 380 pairs in 2009.

Mentor Program

50

2007

Mentor Pairs Chapters

2009

380

2007

2009

1

250

2008

5

2008

21

Responsibility to People

SAFETy AND WELLNESS being a great employer does not end with good benefits packages. Safety on the job is a basic right of our employees and contractors as well. but we go beyond the basics and work toward a goal of zero work-related injuries—because when it comes to the well-being of our people, even one injury is one too many.

Safety at Life TechnologiesWe believe that all injuries and illnesses can be prevented, and that a goal of zero injuries is the only justifiable one for our company.

Our guiding principle is that all operating exposures can be controlled through hazard identification and abatement. Potential hazards are identified through job hazard analysis, safety

New hoists installed to reduce manual handling of heavy packs of powder.

372009 GLObAL CItIzEnSHIP REPORt |

committee input, safety inspections, and reporting of accidents and incidents. We are committed to abating deficiencies systematically through process and equipment changes.

Installing Safety EquipmentIn 2009, our facility in Inchinnan, Scotland invested nearly $1 million to fund equipment changes that contributed to an injury reduction of 68 percent.

• Engineers upgraded downflow booths in the facility’s dispensary to new state-of-the-art clean rooms, which improved the air flow quality for workers.

• the facility also installed a Kardex system to store raw materials in a series of rotating shelves, freeing

up space on the floor and allowing raw materials to be sourced expeditiously. the system has the added benefit of presenting raw materials at the optimum ergonomic height for the dispensary staff.

• A new Atex-compliant Fitzmill mills batches greater than 1.5–5 tons in size using an n2 purge system to ensure an explosion-free atmosphere during the milling process. this equipment allows for the milling of materials with low ignition energies that otherwise could not be milled without the risk of explosion.

• A new hoist facilitates handling of large weights of materials. the hoist has made this much safer for the operatives involved.

Third-party recognition has been achieved by a number of locations: Eugene, OR Voluntary Protection Program Merit Status

Frederick, MD Voluntary Protection Program Star Status

New Zealand ACC Workplace Safety Management Practices Tertiary Level

Warrington, UK 5 Star Award from the British Safety Council

Singapore WSH Council bizSAFE Star

Burlington, Canada Industrial Accident and Prevention Association Level 1 Health and Safety Achievement Award

Inchinnan, Scotland Bronze Award from Healthy Working Lives

Five state-of-the-art containment suites improve air quality and ergonomic workstations.

Responsibility to People

Safety CultureAn injury-free workplace cannot be reached solely through physical changes; significant improvements can only be achieved in combination with a strong culture of safety. Management commitment and grassroots employee involvement are the cornerstones of our safety culture.

• Improvements at our Grand Island, new York facility were the result of a concerted team effort between managers and employees. Managers frequently walk the floor with an eye

toward safety, and make an effort to engage employees in discussions around safety, both informally and at regular team meetings.

the implementation of Safety teams in 2008 empowered employees not only to identify areas for safety improvement but also to implement the needed improvement. In 2009, more than 80 employees volunteered for these teams:

• An Ergonomics team tasked to drive reductions in ergonomic injuries and discomfort

• A Central Safety Committee to manage safety inspections and other safety-related activities

• A Management Level EHS Steering Committee to provide oversight and support all EHS-related activities

• Overall injuries in 2009 decreased 27 percent, more serious injuries that result in lost or restricted work time were reduced by 37 percent, and Workers Compensation costs were lowered by $150,000.

In Grand Island, New York, employees achieved a 21 percent decrease in recordable injuries.

Employees in our Kingsland Grange facility achieved a 54 percent safety improvement over last year.

392009 GLObAL CItIzEnSHIP REPORt |

Safety Awards• At Kingsland Grange in Warrington,

United Kingdom, the safety team reached their target of zero recordable injuries, a 54 percent improvement from the previous year. this was achieved primarily by rolling out the “Deal With It” program, which empowers every employee to be accountable and deal with near misses as they happen. In 2009, not only were there no OSHA-recordable injuries, but we had a side benefit of improved morale and engagement, which helped us earn the 5 Star Award from the british Safety Council.

New trolleys keep high-usage chemicals at a good working height.

Injury Illness Recordable Case Rates

1.30

2008 Baseline

2009

2012 Target

0.80 -38%

-25%0.98

DART (Days Away & Restricted Time) Rates

0.70

2008 Baseline

2009

2012 Target

0.60 -14%

-25%0.52

Injury Illness Recordable Case Rates

1.30

2008 Baseline

2009

2012 Target

0.80 -38%

-25%0.98

DART (Days Away & Restricted Time) Rates

0.70

2008 Baseline

2009

2012 Target

0.60 -14%

-25%0.52

Results are based on 100 employees working 2,000 hours annually.

Workplace Injury and Illness RatesIn 2009, our global OSHA-recordable rate dropped by 38 percent and our DARt (Days Away and Restricted time) rate by 14 percent. this translated to the avoidance of 44 injuries and, therefore, more employees working safely. We will continue to drive hazard abatement, and our safety culture change to achieve our 2012 goal of 25 percent reduction.

Responsibility to People

WellnessImagine an onsite health clinic providing preventive care for our employees, so that employees don’t have to leave work or wait in busy doctors’ offices. Imagine conducting your weekly meeting while burning calories on a treadmill workstation, and then stopping by an onsite cafeteria to pick up a freshly prepared organic meal for you and your family. What about a world-class fitness center located just steps away from your office, where you could participate in group exercise classes and get personal training to meet your fitness goals?

these amenities will be part of our everyday reality at Life technologies. In 2009, we estimated that our U.S. locations experienced 2,500 lost days due to healthcare-related absenteeism. Lost productivity means others have to step in to do the work, causing stress for the individual and the organization. We believe that lifestyle choices like exercising, not smoking, and eating healthier food will create a happier and healthier workforce and reduce loss of productivity.

As part of our overall benefits program, we are committed to providing progressive health and wellness programs that align with our company’s

vision and that address all stages of our employees’ lives, both in and out of work. Our health and wellness efforts focus on addressing five key health behaviors: increasing exercise, smoking cessation, improving diet, reducing stress, and preventing illness. We want to create a culture for our employees and their families where healthy choices and living well are the norm.

• In 2009, Life technologies piloted a new onsite fitness center at our Carlsbad, California headquarters. the center offers state-of-the-art exercise equipment, group exercise classes, and incentive program competitions like Fantasy Fitness. Our satisfaction survey indicated that the center increased frequency of exercise by 76 percent of members polled.

Onsite fitness center in Carlsbad, California promotes a healthy lifestyle.

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• We also challenged employees to adopt healthy behaviors through a walking challenge, piloted in the U.S. in 2009. Each participant received a Life technologies pedometer to track and log steps. the six-week program was completed by 540 employees; as a company, we walked over 256 million steps. Post-program surveys revealed that 76 percent of participants

increased their frequency of exercise and 73 percent improved their overall level of fitness.

• A conference room installed in Carlsbad offers employees a chance to burn calories while they collaborate. the room has 12 treadmill workstations specially fitted with laptop docks and microphones so that employees can hold staff meetings and

focus on their work while burning up to 100 calories per hour by walking at a moderate pace.

Life technologies is committed to increasing investment in our wellness program. Onsite health clinics and cafeterias are at the forefront of these plans.

Healthy choices are promoted throughout our organization.

Cardio conference room in Carlsbad, California.

Responsibility to People

DIVERSITy AND OPPORTUNITyEmployee Diversity Life technologies defines diversity in its broadest sense. Our commitment to global citizenship means we value diversity not only in demographic composition but also in thought, culture, education, and experience. Our innovation and success are a direct result of this diversity, and this diversity delivers a competitive advantage.

We encourage collaboration and teamwork, open debate, personal integrity, honest communication, and individual achievement.

Life technologies is an equal opportunity employer committed to hiring a diverse and inclusive workforce. the company is also committed to affirmative action and

makes good-faith and continuing efforts in this regard. With a total workforce of approximately 9,000 employees globally, Life technologies maintained

a consistent level of diversity within both gender and ethnicity evaluations.

Life Technologies is committed to fostering a professional workplace that promotes teamwork, diversity, and trust.

For Life Technologies, diversity is also embraced in thought, culture, education, and experience.

* Minority ethnic groups indicated for U.S. only and include black or African American, native Hawaiian or Pacific Islander, American Indian or Alaskan native, Asian, Hispanic or Latino, and two or more races.

Workforce by Ethnicity and Gender

Gender Diversity Ethnic Diversity (Women) (Minority*)

2008 2009 2008 2009

Total Workforce 43% 45% 36% 32%

Management 37% 38% 33% 34%

Leadership 28% 29% 21% 20%

Executive 12% 9% 13% 10%

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Supplier Diversity Global citizenship means we are committed to reflecting the rich diversity of our global society not only in our employee make-up but also in the variety of companies with whom we do business.

In 2009, Life technologies launched a revised domestic supplier diversity program aimed at optimizing our inclusion of women-, minority-, and veteran-owned businesses, and all categories of small business ownership, when we make procurement decisions in the U.S. In the first nine months of 2009, Life technologies fell just short of a very aggressive self-imposed goal of 50 percent, achieving 46 percent.

On november 11, 2009 (U.S. Veteran’s Day), Life technologies implemented an incentive program for increasing the utilization of service disabled veteran–owned firms.

Sustainable Supplier PrioritiesLife technologies is also engaging suppliers in our global citizenship initiative by inviting them to join us on our journey to environmental sustainability. Our first Supplier Day was held in 2009 to facilitate the greening of our supply chain. Vendors were asked to provide a road map of their own journey and describe how their products and practices could contribute to moving

Life technologies toward our reduced footprint goals. through this program, Life technologies provides preference to suppliers that value efficiency, ethical practice, and sustainability, based on demonstrated ability to:

• Measure and manage greenhouse gas emissions to reduce the total carbon footprint of Life technologies’ indirect emissions

• Implement new processes to reduce waste and inefficiencies, and establish methods to recycle packaging or supply reusable containers

• Ensure a safe work environment for employees and contractors

• Formally include health, safety, and human rights issues in performance standards, including standards for working hours, freedom of association, and anti-discrimination and anti–child labor practices

• Work within a life cycle assessment to continually minimize the environmental footprint of products, from the selection of raw materials through end-of-life disposal

• Make environmental compliance a priority to avoid business interruption

• Offer environmentally preferable options

Our Supplier Diversity program is designed to ensure that businesses of diverse backgrounds and ownership have the opportunity to become valued suppliers.

The first annual Supplier Day awarded a green award to suppliers that contribute to our footprint reduction.

we redesigned our processes and facilities to meet the promise of our products and technologies—could we help to heal the environment as we improve the human condition?

What if...

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While we are proud of the role we play in moving science forward, we do so with a growing awareness of our environmental impact. We have an appreciation for how we can positively shape the future, not only through our innovative products, but also through the redesign of our processes and facilities.

Responsibility to the Environmentthe old adage remains true: what gets measured gets managed. In developing metrics to monitor and reduce our footprint, we are charting our impact on climate change, resource conservation, and waste reduction. Our planning horizon establishes four-year goal periods. We have set an aggressive eco-efficiency goal of 25 percent reduction in our environmental footprint for the 2008–2012 period. the metrics on the following pages chart our progress to date.

CLIMATE ChANGE

Climate change—the biggest collective action in human history—will dramatically impact how businesses operate in a new, low-carbon economy. At the close of the United nations Conference of Parties (COP) on Climate Change in Copenhagen in December 2009, many were disappointed by the timid results, but most parties agree the conference was a step in the right direction. the conference left in its wake a new accord and a tremendous challenge for businesses and society to take the lead in mitigating and adapting to climate change, with innovation and entrepreneurship at the forefront.

As a global company with a culture of innovation, Life technologies has already begun to take action.

More than 80 percent of our CO2 emissions result from our energy use; therefore, our focus on energy conservation correlates directly with our reduction in CO2 emissions. Energy-saving projects reduced our dependence on nonrenewable sources of energy by 6 percent during 2009, consequently reducing our CO2 emissions by 5 percent—4,500 tons of CO2 avoided.

CO2 Emissions (tons/US$ million of sales)

31

2008 Baseline

2009

2012 Target

30 -5%

-25%23

Responsibility to the Environment

ENERGy EFFICIENCy

With a nearly $2 million capital investment, efficiency gains were realized primarily at our headquarters in Carlsbad, California.

• the existing central plant was retrofitted with an upgraded control system utilizing patented algorithms that reduced energy consumption by 50 percent. Smart software applications were utilized to optimize temperature fluctuations during business hours without impacting the occupant comfort level, and to reduce the temperature changes during off hours.

• biotechnology requires walk-in coolers and freezers for production and storage of temperature-sensitive

products. Over 130 fan motors were replaced with higher-efficiency units and upgraded controls. these motors no longer work 24/7, but instead cycle on only when air circulation is required to maintain cold temperatures. this technology not only allows for 55

percent energy savings, but also provides a tighter temperature control for our products.

• Compressed air is used extensively throughout manufacturing and research laboratories. Leaky nozzles were replaced and compressed air storage tanks were installed. this allowed the demand for compressed air to be met by only one 30HP compres-sor, instead of two 60HP units—reduc-ing the energy consumption of the system by more than 50 percent.

• 2009 marked our dawn of the LED as we replaced our old Edison light bulbs. We replaced inefficient lighting with modern LED and fluorescent lighting, which lasts eight times longer and

Energy Consumption (GJ/US$ million of sales)

242

2008 Baseline

2009

2012 Target

228 -6%

-25%182

472009 GLObAL CItIzEnSHIP REPORt |

consumes one-fifth of the energy. We also use daylight harvesting to automatically reduce lighting when not needed on bright, sunny days.

Given the demonstrated return on investment of these installations, further capital expenditures have been approved to roll out similar conservation projects across Life technologies facilities in the coming years, with a goal of reducing global energy consumption and CO2 emissions by 25 percent, indexed to net sales, by 2012.

LEED CERTIFICATIONAs we build new spaces or renovate our existing buildings, we have adopted the Leadership in Energy and Environment Design (LEED) program from the U.S. Green Building Council as a standard.

In 2009, the company’s new Shanghai Demonstration Laboratory earned LEED Gold Certification. This facility has demonstrated a whole-building approach to sustainability by recognizing performance in five key areas of human and environmental health: energy savings, water efficiency, CO2 emissions reduction, improved

indoor environmental quality, and stewardship of resources.

highlights from the LEED checklist include:

• 77 percent landfill diversion of onsite- generated construction waste

• 19 percent reduction in potable water use

• 17 percent reduction in connected lighting power with installation of daylight-responsive control

• Use of Energy Star–rated equipment equal to 99 percent by rated power

• 12 percent of the total building material content manufactured using recycled materials

• Increased breathing zone outdoor air ventilation rates by more than 30 percent above requirements

In 2003, the Pleasanton, California site became the first Life Technologies site to be awarded a LEED building certification, earning its Silver certification in the early days of the formal LEED program. Our headquarters in Carlsbad, California and buildings under construction in Scotland and China are targeted for certification in 2010.

Solar panels at Life Technologies’ site in Pleasanton, California.

Product cooler modifications resulted in 55 percent energy efficiency gains.

Responsibility to the Environment

A GREEN CULTURE

In addition to our energy conservation efforts, we are benefiting from a grassroots commitment to environmental awareness as our employees become ambassadors for the business.

Projects contributing to our reductions in 2009 include:

• Our corporate rental car partner, Hertz, provided a hybrid vehicle option for our employees. In January 2009, approximately 4 percent of employ-ees chose this eco-friendly benefit. by July, the number soared closer to 60 percent, where it remained the rest of the year. 2009 also marked the launch of a new $500 incen-tive program to sales associates who chose to drive hybrid cars.

• Many employees commuted to work by carpool or public transportation and as a result received back a cumulative $400,000 from the company through our alternative transportation program.

• Our Smart Monitoring Service, which promotes servicing via remote diagnostic tools versus onsite customer service calls, resulted in an avoidance of 520,000 car miles equaling 231 metric tons of CO2

emissions, or 26,000 gallons of gasoline, in 2009.

Our Smart Monitoring Service promotes remote servicing.

Our employees are choosing greener transportation.

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• In an effort to reduce air travel, employees increased use of alternative options and logged more than 1,300 video meetings, 39,500 web meetings, and 175,000 teleconferences instead.

• We saw an increase in voluntary Green team participation to more than 200 employees across 15 sites.

In 2010, we introduced our carbon management plan, which will also take these carbon emissions into

our accounting method. Using the Greenhouse Gas Protocol Initiative as a compass, we began measuring sources of carbon to include business travel, employee commuting, product shipment and transportation, cold storage, and the company fleet.

Teleconferencing helps Life Technologies reduce business travel.

Our Green Team sponsors Earth Day activities annually.

As we improve our data collection process and accuracy, we will further our transparency and reporting through the Carbon Disclosure Project. Life technologies will also continue to work in partnership with the EPA Climate Leaders Program to ensure our strategies are aligned to keep us on track to meet our CO2 reduction goal.

Responsibility to the Environment

WATER CONSERVATION

Clean water is critical to sustaining life. Whether mixing or diluting active ingredients, or cleaning and washing equipment used to manufacture them, all of our consumable products use water. We measure our water usage and evaluate ways to reduce and reuse water in our manufacturing, support utilities, landscaping, and sanitation processes.

In 2009, water conservation projects resulted in a 19 percent reduction in water consumption globally, positioning us well to meet our 2012 water reduction target of 25 percent. In partnership with the San Diego County Water Authority (SDCWA), we implemented water conservation initiatives in Carlsbad to save 20 million gallons of clean, potable water every year, surpassing our initial projection ten-fold.

As California headed into its third year of drought, water-saving initiatives were centered where it mattered most. Improvements included:

• the installation of an emerging technology—the Envirotower—to the existing cooling tower to reduce scaling, corrosion, and microbial contamination, which in turn improves the heat-transfer efficiency of chillers. this project reduces the annual energy consumption by nearly 200,000 kilowatt-hours (kWh) and conserves 2 million gallons of water per year. Installation of these towers in Carlsbad and Austin resulted in estimated savings of more than 3 million gallons per year.

• In Carlsbad, several additional large projects were completed. We installed autoclave trap cooling kits to prevent continuous discharging of condensed clean steam to waste. two clean steam generators were reconfigured to use heated soft water—water recycled from another process on the line. Retrofits were made to the room that houses ultrapure water for all of the manufacturing and R&D lab use within one building. the reverse osmosis/deionized water systems were reconfigured. Additionally, the landscape irrigation system was

converted from a conventional system to a grey water system that utilizes nonpotable water. Combined, these projects resulted in total water savings of more than 6 million gallons per year.

• In Pleasanton, the landscape irrigation system was updated with higher-efficiency nozzles, and the water supply was converted to a grey water system. these improvements are estimated to result in water savings of 1,730,385 gallons per year.

• Water conservation goes beyond California. Our facility in Auckland, new zealand has a long-standing record of environmental stewardship. In their water-intensive serum manufacturing business, water and energy efficiency are key drivers to cost reduction. In 2009, the site redesigned the manufacturing process to streamline an outdated line and optimize water utilization, which in turn resulted in a 100 percent utilization rate for the serum produced on the line. Although the plant increased production, the site achieved annual water savings of 8.7 million gallons.

Modifications to the cooling tower for the central plant in Carlsbad, California conserve 2 million gallons of water per year.

Water Consumption (m3/US$ million of sales)

252

2008 Baseline

2009

2012 Target

205 -19%

-25%189

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WASTE DISPOSAL

Modifying our manufacturing processes to eliminate waste streams and developing viable programs to recycle are part of our environmental agenda.

In 2009, our waste disposal process was optimized at several sites to single- stream recycling. As a result, waste segregation became the responsibility of the recycler; this program increased recycling from 33 kg/US$ million of sales in 2008 to 4,619 in 2009—setting a new baseline. Life technologies also achieved a hazardous waste decrease of 4 percent in 2009.

Highlights include:

• In Frederick, Maryland, engineers achieved significant waste reduction as they faced a global shortage of acetonitrile, a solvent used in oligonucleotide manufacturing, which normally represents 50–75% of the solvents consumed by DnA manufacturing. In a systematic analysis of the protocols used for the high-throughput DnA synthesis, every step that used acetonitrile was tested to see if a lower amount could be used without affecting product quality. the project resulted in a reduction of acetonitrile usage for most syntheses by over 20 percent, substantially reducing the hazardous waste generation for the site.

• At our bedford, Massachusetts site, substantial wastewater was generated during solvent washes and water rinses. According to site metrics, 100,000 gallons of aqueous hazardous waste were generated in 2008. In 2009, the team set a goal of reducing aqueous hazardous waste by 25 percent. the team analyzed the waste to determine if more water could be diverted from the aqueous waste tank to the wastewater treatment system. the results revealed that 32 percent of the waste sent to the aqueous waste tank was clean enough to be sent to the wastewater treatment system. the findings will save an estimated $50,000 annually and result in less frequent hazardous waste shipments, reduced fuel consumption, and fewer CO2 emissions.

Hazardous Waste Generation (kg/US$ million of sales)

517

2008 Baseline

2009

2012 Target

496 -4%

-25%387

Life Technologies recycled over 14 million kg of material in 2009.

Responsibility to the Environment

IdeationWe aim to build energy-efficient instruments from the outset, developing alternative solutions that eliminate or minimize exposure to hazardous materials, and incorporating concepts of source reduction, reuse, and recycling into product design.

• the Ab 3500 xL Genetic Analyzer is more energy-efficient and is composed of fewer materials than its predecessor, the Ab 3130xL Genetic Analyzer. Fewer materials result in a lighter-weight product requiring less fuel consumption and associated greenhouse gas emissions for transport. Use of fewer materials also translates to less waste at end-of-life.

• the use of Cells-to-Ct™ systems eliminates the need to use hazard-ous chemicals associated with traditional RnA extraction and clean-up. this includes ethanol, mercaptoethanol, guanidine thiocya-nate, and guanidine hydrochloride.

SourcingWe consider the environmental, health, and safety and regulatory impacts in material selection, asking questions such as: Can we use recycled materials? Can the materials be sourced from renewable resources? Can we source locally?

• the Veriti® thermal Cycler is safer and easier to recycle because it is designed free of key hazardous substances commonly found in electronic products (e.g., lead, mercury, cadmium, hexavalent chromium, polybrominated flame retardants).

ManufacturingManufacturing processes should utilize the least hazardous and smallest amounts of chemicals, energy, water, and other natural resources. We aim for zero emissions and efficient production in the factory of the future.

• the manufacture of SOLiD™ 4.0 includes a slide preparation process that uses large amounts of solvent. the state-of-the-art method for preparing these slides involved the use of a solvent reputed to cause birth defects. In seeking less hazard-ous alternatives, the SOLiD™ slide team identified a much safer com-bination of ethanol and acetic acid.

PRODUCT STEWARDShIP

through the Product Stewardship program, Life technologies strives to continuously assess and improve the health effects, safety, and environmental impact of our products, processes, and services throughout the product life cycle. We go beyond compliance, incorporating Design-for-Environment principles from ideation to end-of-life.

Ideation Sourcing Manufacturing

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DistributionPackaging and transport of products have significant cost and environmental impact. Designing products for ambient shipment vs. cold chain is one way to mitigate costs and increase customer satisfaction.

• through a combination of positive engagement with regulatory authorities and application of green chemistry strategies, we were able to reduce our products classified as hazardous for transport by 15 percent. this means they are safer to use and dispose of and require less packaging.

• Over 400 Molecular Probes® products, including Alexa Fluor® dyes, Qdot® nanocrystals, Click-it® detection assays, and ProLong® Gold antifade reagents, have been packaged in new pouches, using up to 92 percent less plastic than the original plastic jars. this translates to fewer raw materials, less energy to produce and transport, and less waste in landfill.

UseCustomers prefer to work with materials that minimize their exposure to hazardous materials. They also look for products that help achieve their facility’s environmental targets (e.g., energy efficiency, reduced waste, less consumption of water and other natural resources).

• the StepOnePlus™ Real-time PCR product is more energy-efficient, utilizes less raw material, and is less hazardous for disposal than its predecessor, the 7300 Real-time PCR System. the StepOnePlus™ Real-time PCR System is safer and easier to recycle because it does not contain lead, mercury, cadmium, hexavalent chromium, or selected brominated flame retardants.

End-of-LifeWe are expanding our programs to encourage reuse of instruments at end-of-life.

• Leading the way is our Genetic Analysis group, with established col-lection and refurbished programs for our 3100, 3130, and 3730 instru-ments in partnership with Hitachi High tech. In addition to reusing high-quality parts, we were able to refurbish 157 instruments in 2009.

Life technologies has adopted a cradle-to-cradle mindset for product design, and in 2009 launched a toolbox that describes a new paradigm to our product lifecycle. We have applied different aspects of thinking to new products, with an ultimate goal of 100 percent cradle-to-cradle design, manufacture and reclamation.

Distribution Use End-of-Life

Responsibility to the Environment

SUStAInAbLE PACkAGInG

Cold transportation remains our single largest environmental challenge, and we are very concerned about the impact of our packaging on the planet and on our customer relations. the implications go beyond our own doors; our packaging creates waste that leaves our customers with disposal issues.

to ensure product quality and safety, more than 50 percent of our products require that they be delivered either refrigerated or frozen. We ship these to our customers in expanded polystyrene (or EPS, sometimes called Styrofoam™) coolers, packed with dry ice or gel ice so that they travel and arrive at their destination at temperatures that maintain product performance.

While our customers value the quality of what we deliver, feedback from around the world continues to indicate that our packaging practices must change, so that our packaging does not become our customers’ waste.

Unfortunately, the number of complaints has increased recently after changes to our shipping practices. to meet our customer’s demands for receiving product on Mondays, we now ship on Fridays and Saturdays. A product leaving our distribution warehouse on Friday needs to stay cool for up to 72 hours, until it can be delivered to the scientist’s bench the following Monday. this increased product transit time requires an upsized cooler to accommodate more dry ice and gel packs.

With 1 million cold storage shipments annually, the use of EPS coolers is our largest environmental issue.

“By now I have three big Styrofoam boxes, which I am

reluctant to trash.”

“This small 1 ml pack often arrives in a 17 x 13 x 13 inch box

that weighs 20 lb.”“Your customers

expect more from an industry leader!”

“The packing weight ratio is over 3,000!”

“The packaging was grotesquely excessive.”

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STEP 1: ELIMINATING THE NEED FOR COLD SHIPMENT Where feasible, we design new products that can withstand the rigors of ambient shipping conditions. For example, we have found that a portion of our trypsin product line can ship under ambient conditions; our competitors continue to ship this frozen in EPS coolers.

In addition, we are systematically evaluating potential product candidates to convert from cold chain to ambient shipment. In performing stability and performance tests, we seek to demonstrate that short-duration ambient transport has no effect on the immediate and long-term quality of certain products.

Recently we have completed these tests on four classes of assays (taqMan® Genotyping Assays, taqMan® Gene Expression Assays, taqMan® miRnA Assays, and the Megaplex™ PreAmp and Rt primer pools). After subjecting these products to simulated ambient summer shipment conditions, they were found to meet the same quality-controlled stability and performance specifications throughout their stated shelf life as assays that were shipped on dry ice. by shipping at ambient conditions, we eliminate 70,000 cu. ft. of EPS (equivalent to filling 694 standard dumpsters) and 250,000 kg of dry ice annually.

beyond studying the ability of our products to withstand ambient shipping conditions, we also look at alternative manufacturing methods such as lyophilization and vitrification. these drying methods preserve the biological material by removing water, making it less susceptible to temperature variations and more convenient for transport.

One of the company’s best-performing influenza detection kits is our newest lyophilized product. Our lyophilized reagents are being designed with an eye towards stability, both in transport and on customer shelves.

STEP 2: IMPROVING THE PACKAGING FOR COLD SHIPMENT For products that must be delivered at cold temperatures, we (1) right-size coolers, (2) use reusable packaging delivery methods, and (3) seek alternative materials.

Right-sized coolers by decreasing the wall thickness, material density, and size, we have reduced the usage of polystyrene by 30 percent—the equivalent of 52 truckloads per year.

We also stock a range of box sizes to optimize the weight and cooling requirements of the order. An extremely small cooler, the mini-mini, has been designed to ship our smallest products. this cooler uses 17 percent less EPS than the next larger size.

Reusable packagingWe piloted the internal use of bulk reusable coolers in place of EPS coolers. Due to the improved thermal efficiencies of these units, we can reduce our dry ice consumption by 37,000 pounds and eliminate 9,000 pounds of one-way packaging material. We are looking to expand this practice to our customers.

Additionally, we enhanced our product supply centers so that bulk shipments can be received and broken into smaller shipments to go to customers, and/or be hand-delivered so that coolers can be reclaimed and reused.

In Japan, we switched to sturdier flexible plastic coolers that can be returned for reuse by the distributor who hand-delivers products to customers. the market in large cities in Japan demands same-day or next-day delivery, so

requiring distributors to switch to these more efficient coolers packed with reusable gel ice packs eliminates the need for EPS coolers packed with dry ice.

In taiwan, we use reusable rigid plastic coolers. Products are hand-delivered to customers, and the coolers are returned by the delivery personnel.

Alternative materialsWe are continually researching alternative packaging materials to EPS. We have tested felt, wax-insulated cardboard, insulated padded envelopes, air-filled plastic liner coolers, chiller bags, reusable thermal boxes, and more. Although none of these alternatives meets the thermal requirements necessary to maintain our product quality standards, we continue to search for innovative alternatives.

“ We find ourselves today at an intersection where the powerful solutions that we can enable as a company are sometimes in conflict with our commitment to a smaller footprint. We recognize that the majority of the one million Styrofoam™ coolers we ship annually end up in landfills. As a result, we have set a north star goal to eliminate cold chain transportation so that we can help our customers achieve the goal of zero waste in a low-carbon economy.”

—Cristina Amorim, Vice President, Global EHS and Citizenship

companies that aspire to be great also focused on being good?What if...

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For Life Technologies, giving back is not just about philanthropy, it’s about engagement—reaching the communities where we work, into the world of science and education, and into the markets where our products and technologies are put to use, is just good business. It’s truly a mutually beneficial relationship.

Community is supported through two key mechanisms at Life technologies—corporate and philanthropic. Corporate community relations activities include volunteerism, sponsorships, service projects, a speaker’s bureau, board service, facility tours, and product donations. the Life technologies Foundation manages many of Life technologies’ philanthropic activities and includes science education–related grants, disaster relief, and other donations.

GIVING BACk AT LIFEGiving back at Life is more than a community service effort; it is a structured program of opportunities that enables the company and its employees to give time, talent, and resources. Opportunities include volunteering to help others in need, sharing skills and talents with the scientific leaders of tomorrow, and offering Life technologies products and financial support for important programs in local communities. Giving back at Life is a way to bridge the boundaries between the company and the community, bringing us closer to the places we work and the worlds of science and education.

Volunteering Our Time On Global Volunteer Day, the company provides each of its employees with a half-day of paid time to participate in a volunteer project. In 2009, nearly 3,200 employees at Life technologies donated their time to more than 146 projects at 82 global sites during the company’s sixth annual Global Volunteer Day—the first since Invitrogen and Applied biosystems came together to form Life technologies.

Projects ranged from helping middle school students in East Palo Alto, California, to cleaning beach litter with the national Environment Agency in Singapore. While some employees were beautifying the grounds of the Science Factory in Eugene, Oregon, others were working in Cubbon Park to help attract visitors in bangalore, India. the diverse tapestry of projects reflected the many personalities of Life technologies, but was woven with a single thread: giving back.

Responsibility to Community

Responsibility to Community

Sharing Our Talentsthroughout the year, Life technologies employees are empowered to identify and participate in opportunities to donate their time and talents in ways that are meaningful to them and that further the understanding, appreciation, and application of the life sciences.

In 2009, the web portal Giving back at Life was launched to help employees find these opportunities and log volunteer hours to earn rewards. In 2010, Giving back at Life is now tracked via AngelPoints, a program that allows companies around the world to manage and measure their community involvement initiatives and recognize and reward their volunteers.

AngelPoints provides new ways of measuring and quantifying our impact, and helps Life technologies ensure that our community relations activities are appropriately aligned with our collective goals and objectives.

Highlights from 2009 include:

• Donating human identification kits to help identify victims of a bush fire in Australia.

• Hosting 80 girls in a science laboratory in Austin, texas, and introducing them to the world of forensics by extracting DnA from their cheek cells, running the DnA on gels, and performing fingerprinting and analysis.

Paying It Forward When Life Technologies’ first Global Quality Leadership Team Meeting was held in San Diego, California, last year, the group was pleasantly surprised to find out that the meeting’s typical get-to-know-you team-building exercise would also be a public service project. Forty-two individuals from around the world visited the San Diego Food Bank and broke into two competitive teams. Working together to understand each other’s strengths, communicating, encouraging each other, and using their quality experience to visually inspect and sort food produced a successful

outcome—for our employees and for the food bank. In less than 2 hours, the two teams sorted 9,000 pounds of food, enough to feed 100 people for 18 days. The success of this service project inspired other teams to follow suit.

Sharing our talents in forensic science.

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• Giving personal time. Scientist tatiana Cirico went to Mexico to assist in a hands-on biology course for underserved youth, while scientist John Pfeifer spent his vacation time developing and teaching a PCR course for gifted students in Houston, texas.

• Co-sponsoring the launch of the Milwaukee School of Engineering Science Olympiad Protein Modeling trial event in Madison, Wisconsin.

• Donating to the Camarillo, California school district’s library system for science-related books and audio/visual materials targeted at 4th through 6th graders.

Creating planter boxes for the Glenner Alzheimer’s Family Center.

Responsibility to Community

Donating Our Resourcesby teaming with researchers across countries and cultures, we strive to demystify the world of life science, empower today’s children to become tomorrow’s scientific leaders, and deepen society’s appreciation of science and its profound impact on our lives. the Life technologies Foundation provides grants in areas such as the advancement of science through public policy initiatives, promotion of science education, and improvement of scientific and medical training.

In 2009, the Foundation awarded approximately 30 grants and obligated nearly $5 million. the company also matched approximately $520,000 in employee donations to hundreds of nonprofits globally. Although the matching gift program was phased out in 2009, the Life technologies Foundation

will continue employee matching campaigns for disaster relief, such as the campaign for Haiti earthquake relief conducted in early 2010.

In 2009, Foundation grants included $2 million to several recipients working to advance science, including the new York Academy of Sciences and the Science Museum in London. A partial listing of recipients is included here; more information is available online.

the new York Academy of Sciences received a grant to train medical students and doctors in using genomics to better understand health and disease. this training will be conducted via online and in-class curricula and will also educate current and future doctors on the use of computerized medical records.

the Science Museum in London will refurbish and update their “Who Am I?”

exhibit that launches in June 2010, examining how modern science is transforming our understanding of what it means to be human. It will focus on the Human Genome Project, regenerative science, 21st century medicine, and using DnA for applications like forensics and population mapping.

Ocean Discovery InstituteWhen you live alongside the rich marine environment of the Pacific Ocean, it’s only natural to look to the ocean as your teacher. That’s what the Ocean Discovery Institute has done, and Life Technologies supports this nonprofit organization’s programs with funding, in-kind donations of scientific equipment and supplies, and the participation of our scientists. The Ocean Discovery Institute runs tuition-free educational programs for 5,000 urban, disadvantaged, and minority youth each year, using science, the ocean, and nature to inspire and empower them. The mix of

Empowering today’s children to become tomorrow’s scientific leaders.

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Grant recipients in 2009 included:

• Science Museum in London—sponsor Who Am I gallery (exhibit on human genome and 21st century medicine)

• new York Academy of Sciences—train physicians on new technologies

• DnA-Prokids—expand human identity tracking

• PbS to the Contrary (bonnie Erbe Show)—advancement of DnA sequencing as a diagnostic

• Reuben H Fleet Science Center—Cellular Journey: Stem Cells & Cells of Human body

• zoological Society of San Diego—conservation education

• EO Wilson Foundation—Life on Earth Phase I prototype, the Cell

• WGbH nOVA sciencenOW—sponsor season 5 nOVA sciencenOW

• Miami Institute for Human Genomics—promote genomic literacy in minority populations

• Medical College of Wisconsin—women pioneers in science sponsorship

• University of Arizona DnA Shoah Program—using genomics for human identification

• boojum—traveling honeybee program for children

• San Diego High tech High – African bushmeat—DnA training course in tanzania

• Red Cross—Australian wildfire relief

classroom-based experimental science, intensive after-school and summer programs, and community-based habitat restoration provides more than 48,000 hours of instruction annually.

Each year, the top 20 to 28 students in the Ocean Discovery Institute are invited to join its Ocean Leaders program. This intensive course includes 11 weeks of training and preparation in San Diego, five weeks working on actual research projects at the Vermillion Sea Field Station on Bahía de Los Angeles in Baja California, and three weeks debriefing and presenting their

results. The field station is located among 17 nature-rich islands in the Sea of Cortez along Baja’s eastern coast, about 450 miles south of San Diego.

In 2009, Life Technologies sent Associate Scientist Tatiana Cirico from the Genomic Technologies group of the Molecular Biology Systems Division to the Bahía site to introduce the students to DNA, cloning, and protein expression. “I wanted to link the talk to the subjects they were studying,” Cirico says, “so I described the fluorescent proteins we use as markers in cell biology and related them to the bioluminescence

exhibited by many marine organisms.” For a hands-on experiment, Cirico conducted an experiment in which the students extracted DNA from strawberries using simple household chemicals. “That was exciting for them,” she says. “The solution was even pink!”

Life Technologies Foundation Grants(US$ million)

.50 million

2008

2009

5.54 million

Rotkreuz, Switzerland

Foster City, California

Buenos Aires, Argentina

Oslo, Norway

Darmstadt, Germany

Austin, Texas

Global Volunteer Day 2009

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Budapest, Hungary

Auckland, New Zealand

Tokyo, Japan

Shanghai, China

Singapore

Seoul, South Korea

Prague, Czech Republic Warsaw, Poland

Global Volunteer Day: 13,000 hours

Group service projects: 629 hours

Charity drives: 51

Blood donations: 576 pints of blood

Clothing donations: 316 boxes

Toys collected: 1,037

Cb

A

Food donations: 2,144 pounds

Site tours: 58 events

Community outreach events: 364 hours volunteered

Committed Foundation grants and matching gifts: ~$5,000,000

Corporate donations and sponsorships: $487,000

Product donations: $41,000

Board assignments: 29

2009 in Review

652009 GLObAL CItIzEnSHIP REPORt |

Awards and RecognitionDow Jones Sustainability World Index (2008 and 2009)

Life technologies was again selected as a member of the Dow Jones Sustainability World Index in 2009, and was also named to the Dow Jones Sustainability north America Index (DJSI). Membership in the DJSI is reserved for the top 10 percent of the 2,500 largest companies in terms of sustainability, and Life technologies was one of only two U.S.-based biotechnology companies to be listed on both the north America and World Indexes. In 2009:

• Overall sustainability score increased from 67 to 80, rising from bronze to Gold Class.

• Received a 100 percent score for eco-efficiency, and was singled out as having the highest performance across the biotechnology sector for talent attraction and retention, supplier management, and workplace safety.

• transparency score increased from 7 to 41.

FTSE4Good In May 2009, Life technologies was named to the FtSE4Good Index Series, an equity index series that is designed to facilitate investment in companies that meet globally recognized citizenship standards. Companies in the FtSE4Good Index Series have met stringent social, ethical, and environmental criteria.

Bloomberg-Maplecroft Climate Innovation Index Leaders In late 2009, Life technologies was named to the bloomberg-Maplecroft Climate Innovation Index (CII) Leaders. As a member of the CII Leaders, we rank among the top 100 of the 819 largest U.S.-based companies in terms of climate-related innovation and carbon management programs.

Corporate Responsibility Magazine “100 Best Corporate Citizens” ListIn 2010, Life technologies was named to the 100 best Corporate Citizens List by Corporate Responsibility magazine. the list is based on over 360 data points of publicly available information in seven categories: Environment, Climate Change, Human Rights, Philanthropy, Employee Relations, Financial Performance, and Governance. Life technologies was ranked 78th.

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Data Summary table

Section & Indicator1 Units 20082 2009 Change

Company Profile

Non-GAAP Revenue $M 3,145 3,303 159

Non-GAAP R&D Expenses $M 323 334 11

Non-GAAP Taxes $M 220 219 -1

Effective tax Rate % 27.7 28.5 0.8

Non-GAAP Net Income $M -- 551 --

Non-GAAP EPS $ -- 3.04 --

Free Cash Flow $M -- 534 --

Share Price US$ 23.31 52.22 28.91

Patents & Exclusive Licenses # of 3,600 3,900 300

Facilities # of 82 82 0

Board of Directors

Total Board Size # of 13.0 13.0 0.0

Independent Directors % 12.0 12.0 0.0

% Women % 7.7 7.7 0.0

Average Age # of 62.5 63.5 1.0

Average Compensation $M 0.2 0.3 0.1

Employees

Employees by Region # of 9,725 8,772 -953

EMEA # of 2,024 1,675 -349

north America # of 5,925 5,449 -476

South America # of 115 119 4

APAC # of 1,661 1,529 132

Employees by Type

Full-time employees # of 9,543 8,621 -922

Part-time employees # of 182 151 -31

Contract/temporary workers # of 929 1,146 217

Ethnic Diversity3,4 % 36 32 -4

Management (managers and senior managers) % 33 34 1

Leadership (directors, senior directors, vice presidents) % 21 20 -1

Executive (senior vice presidents, and above) % 13 10 -3

Gender Diversity (Women) % 43 45 2

Management (managers and senior managers) % 37 38 1

Leadership (directors, senior directors, vice presidents) % 28 29 1

Executive (senior vice presidents, and above) % 12 9 -3

Supplier Diversity3

Small business $M 186.4 271.4 85

Small Disadvantaged business $M 2.2 8.4 6.2

Woman-Owned business $M 15.7 21.2 5.5

Veteran-Owned business $M 5.8 11.5 5.7

Service Disabled Veteran business $M 2.6 2.2 -0.4

HUbzone $M 2.4 2.1 -0.3

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Section & Indicator1 Units 20082 2009 Change

CO2 Emissions5

Total Emissions (Scope 1 & 2)6 tons CO2e 98,219 95,177 (3,042)

normalized by sales tons CO2/$M 31 30 (1)

Energy Usage # of 13.0 13.0 0.0

Total Direct Nonrenewable Energy Sources GJoules 316,360 296,107 -20,253

natural gas GJoules 315,787 295,639 -20,148

Fuel distilled from crude GJoules 573 469 -105

Total Direct Renewable Energy Sources GJoules 0 0 0

Total Intermediate Nonrenewable Energy Sources GJoules 447,260 435,832 -11,427

Total Intermediate Renewable Energy Sources GJoules 0 0 0

Total Energy Usage GJoules 763,620 731,940 -31,680

normalized by sales GJoules/$M 242 228 -14

Water Usage

Total Municipal Water Usage m3 796,106 658,042 -138,064

normalized by sales m3/$M 252 205 -47

Waste Generation

hazardous Waste kg 1,632,683 1,590,820 -41,863

normalized by sales kg/$M 517 496 -21

Nonhazardous Waste kg 3,522,936 24,818,067 21,295,132

normalized by sales kg/$M 1,115 7,736 6,621

Recycling kg 1,051,711 14,817,478 13,765,767

normalized by sales kg/$M 333 4,619 4,286

health & Safety

Injury/Illness

Recordable injuries Rate 1.3 0.8 -0.5

DARt Rate 0.7 0.6 -0.1

Fatalities # of 0.0 0.0 0.0

Safety Committee Membership (Employees) % -- 5.4 --

Product

Dangerous Goods (Green Chemistry Application) % Change -- -15.0 --

Philanthropy

Foundation Grants $M 0.50 5.54 5.04

Cash Donations $M 0.21 0.49 0.28

Product Donations $M 0.02 0.04 0.02

Cost & Investment

Investment in Sustainability $M -- 1.71 --

1Unless stated otherwise, the data have an estimated coverage of 95%.2The year ended December 31, 2008, provides an “as if” Invitrogen and Applied Biosystems were combined for the year beginning January 1, 2008.3U.S. only. 4Minority ethnic groups include: Black or African American, Native Hawaiian or Pacific Islander, American Indian or Alaskan Native, Asian, Hispanic or Latino, and two or more races.5Greenhouse gas (GHG) emissions have been accounted for and reported as CO2 in accordance with the World Resource Institute (WRI) GHG Protocol.6Natural gas and heating oil consumption used in direct-fired fuel burning equipment at our locations, and electricity consumption from our operations.

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APPEnDIx A: LIFE tECHnOLOGIES StRAtEGY AnD PROFILE—GRI InDEx

GRI Indicator Where Reported

Profile Disclosures Strategy and Analysis: 1.1 7

Organizational Profile: 2.1–2.101 4, 5, 65, 66

Report Profile, Scope and boundary: 3.1–3.81 69

Report Scope and boundary: 3.5–3.8, 3.10–3.11 69

GRI Content Index: 3.12 66

Governance: 4.1–4.41 66

Stakeholder Engagement: 4.14–4.15 69

Economic Economic Performance: EC1 5, 66

Indirect Economic Impact: EC8 66

Environmental Energy: En3, En4, En5 67

Water: En8 67

Emissions, Effluents and Waste: En18, En22 67

Social Employment: LA1, LA3 66

Occupational Health and Safety: LA6, LA7 67

training and Education: LA12 23

Child Labor: HR6 24

Forced and Compulsory Labor: HR7 24

Corruption: SO2, SO3 22-27

Public Policy: SO5, SO6 22-27

Customer Health and Safety: PR1 51-52

Compliance: PR8 24

1Information responsive to this indicator appears on our website: www.lifetechnologies.com

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ABOUT ThIS REPORT

this is the second Life technologies Global Citizenship report, and the first annual report that follows the generation 3 (G3) guidelines of the Global Reporting Initiative (GRI). the previous report covered the 2008 time period and can be found at www.lifetechnologies.com.

this report covers 2009 performance data and activities at manufacturing, distribution, sales, services, support, and training facilities worldwide for the period ending December 31, 2009. It does not address the performance of our joint ventures, third-party manufacturers, suppliers, or contractors. this report also covers 2010 where the information adds clarification to the described 2009 activities.

this report addresses the full range of material economic, environmental, and social impacts of the organization, within the context of the boundary of the report as described in Appendix A, GRI Index. the basis for reporting on facilities does not significantly affect comparability from period to period. there were no effects of any restatements of information identified in this report.

through this report, we hope to convey to you how we conduct our business sustainably; living as a global citizen is at the core of our values. We look forward to developing a dialog with our stakeholders and welcome your feedback through our website, www.lifetechnologies.com.

Other documents of similar interest available at www.lifetechnologies.com include our 2009 Annual Report.

Please submit any suggestions for improvements to this document to:

Meredith Raymond [email protected]

Except as otherwise indicated by the context, the terms “Company” or “Life technologies” as used herein mean Life technologies Corporation and its consolidated subsidiaries.

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UNITED STATES hQLife Technologies Corporation5791 Van Allen WayCarlsbad, CA 92008 USATelephone 760.603.7200Fax 760.602.6500

© 2010 Life Technologies Corporation. All rights reserved. The trademarks mentioned herein are the property of Life Technologies Corporation or their respective owners.


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