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ANNUAL PROGRESS REPORT

Clinical & Chemical Pathology

Department

Reporting period: January 2011– December 2011

Chair of the Department: Prof. Dr. Safaa Al-Karaksy

Prepared by: Dr. Nelly Abulata

Lecturer of Clinical Pathology

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Table  of  Contents   I. Letter from the Chair……………………………………………………………………………………3 II. ClinChem at a glance 1 About us …………………………………….……………………………………………..…….….4 2 Role of the Department………….…………………..………………………………..……….…...5 III. Human Resources……………………………………………………………………………..………6 IV. Organizational Chart………………………………..………….……………………………………....7 1 Deputies……………………………………………………………………………………….…..…..7

2 Seniors of Each Division…………………………………….………………………………………..8

3 Secretary General for the Council of the ClinChem Department & Technical Development Officer…8 4 Executive Team…………………………………………………………………………………….....8

5 Executive committees……………………………………………………………………………..…10

V. Laboratory Services we provide…………………………………………..……………………..….....11 1 Background Information…………………………………..……………………………….………......11 2 Total Annual Productivity…………………………………..…………………………………………12 3 Productivity per Lab..……………………………………………………………………………….....14

4 Productivity per division……………………………….…………………………………….……..…18 5. Blood Bank Services…………………………………………………………………………….…....18 VI. 2010 Activities & Accomplishments……………………………………..……………………….…19 1. Scientific Research …………………………...…………………………..…………...……………...19 2. Promotions…………………………………. ………………………………………………………22 3. Quality Assurance Committee for Laboratory Services……………………………………………....22 4. Quality Assurance Committee for Education………………………………………………………...23 5. Training courses/ workshops………………………………………………………………………...23 6. ClinChem Conferences………………………………………………………………………………24 7. ClinChem website……………………………………………………………………………………27

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I- LETTER FROM THE CHAIR: During 2011, the Clinical and Chemical Pathology Department continued its tradition of 3 CCCs of Togetherness which are: Collaboration, Cooperation and Communication. Working together with 250 faculty members, nearly 44 residents and several hundred Technologists & Technicians, nurses, administrators, and staff who make up the department, we have made rapid strides toward achieving those goals. This year we achieved an overall annual productivity of 4,598,604 tests which could not have been reached without our dedicated manpower (1,000 employees). With the appointment of new Heads of Laboratories, Heads of Units and Laboratory Directors and with the creation of an Executive Committee, the Department now has the infrastructure it needs to continue its path.

All through 2011, we continued a steady expansion in our three major missions; Laboratory Services, Teaching & Training and Research Activities. In the Laboratory service arena, we continued to push ahead with the implementation of Quality Assurance System at Al– Manial Clinical Pathology Laboratory and Chemical Pathology Laboratory which will expand to the rest of our labs very soon. A new IT system was introduced during March 2011 at Abou El-Rish Lab. With that implementation there is interfacing between the Lab machines and the Lab computer system in 5 out of our 8 Labs. Teaching & Training activities also remained very strong. Our goal is to train Clinical & Chemical Pathologists who will make a difference whether they chose a career path in academic medicine or in clinical practice. In addition to the pre– master & pre-doctorate teaching & training programs we now offer a 2 week condensed summer training program to undergraduate students.

In the Research arena, several research projects were funded by the faculty under the roof of the 2-5yr plan for the Research activities of the Department which involved all 4 specialties of the Department (Hematology, Immunology, Microbiology and Chemistry. As for our international publications, over 20 articles were published by our faculty, several of which were in the high impact journals. Another source of pride was that the Department held a third very successful Scientific Conference; 3rd CLINCHEM 2011 “Genetics and Tissue Engineering”, which was held at the Cairo International Conference Center from 3rd - 5th of April, 2011. The Department is building on an extraordinary legacy and we plan to make it a yearly event. There is also a collaborative initiative with the Egyptian Society of Laboratory Medicine in their upcoming Conference that will be held during April 2012. In summary, the Department remains strong and undergoing carefully planned incremental growth, reflecting both our role in academia and in Laboratory service. With the opening of the 2 new Labs at the New Maternity Hospital and New ER Hospital we look forward to gradual recruitment of several more staff and also to working closely with all of our other colleagues in the Faculty and Hospital to build our research, teaching and clinical enterprise in a fashion that melds with programmatic directions of the University as a whole. Prof. Dr. Safaa Al-Karaksy

Chair, Clinical and Chemical Pathology Department

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II- CLINCHEM AT A GLANCE: 1- ABOUT US

Mission “Is to provide excellence in Laboratory services, Teaching, Training and Research activities”.

Vision We aspire to be recognized as an Academic Department of excellence to support and enhance the mission and vision of Kasr Al-Ainy Faculty of Medicine, Cairo University. Objectives 1. To provide excellent laboratory medicine services for the patients of Kasr Al-Ainy

Hospital in a timely & professional manner.

2. To provide an atmosphere of respect for our staff while encouraging continued personal growth, education and development.

3. To provide excellent teaching to a broad spectrum of health care professionals, health care workers and Lab personnel in conjunction with The University.

4. To provide the physical facilities and atmosphere where research activities can flourish, in collaboration with Kasr Al-Ainy Faculty of Medicine and other affiliated institutions.

5. To promote health, treatment and prevention of disease in the diverse population which we serve.

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2- ROLE OF THE DEPARTMENT

1. Laboratory services: The Department offers Clinical and Chemical Laboratory services designed to meet the needs of physicians, & patients. The Department has 2 Main Labs at Al-Manial Hospital, a Lab. in each of the following Hospitals; the Specialized Hospital (4th Floor), the Internal Medicine Hospital, the Pediatric Japanese Hospital , the Pediatric Abou Elrish Hospital, King Fahd Hospital, the French Hospital in addition to Emergency Labs that offer the Lab services during the evening and night shifts. The Department is also responsible for the Technical supervision of the Blood Bank.

2. Teaching & Training: The Department is committed to providing strong and balanced Teaching and Training programs mainly to Postgraduate students, principally in the Master and Doctorate degrees in Clinical and Chemical Pathology tailored to each student subspecialty (Hematology, Immunology, Microbiology or Chemical Pathology). The Department is also partly involved in the Teaching & Training of postgraduate students of other Departments enrolled in Master, Diplomas & Doctorate degrees in addition it provides instructional courses to the 6th year students. And recently this summer we offered a condensed 2 week training course to undergraduate students.

3. Research activities:

The Research Faculty members within the Department are nationally recognized. The Research ranges from clinical to basic Research, with an emphasis on Hematologic Malignancies, Virology & Molecular Genetics.

Laboratory    Services  

Research  Teaching  &    Training  

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III. HUMAN RESOURCES

The Department has a total manpower of 1,003 employees. This comprises: · 318 Doctors; 250 Faculty members, 24Specialists & 44 Residents

. 393 Technologists & Technicians

· 62 Nurses

· 141 Administration

· 89 Cleaners

250  

24  44  

Doctors  

Faculty  staff  

Specialists  

Residents  

318  

393  

62  

141  

89  

0  

50  

100  

150  

200  

250  

300  

350  

400  

450  

Doctors   Technologists  &  Technicians  

Nurses   AdministraHon   Cleaners  

Human  Resources  

Doctors  

Technologists  &  Technicians  

Nurses  

AdministraHon  

Cleaners  

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IV- ORGANIZATIONAL CHART The Organizational structure has been modified and effective teams have been built aiming to introduce the “we” culture and a more qualitative workplace.

1. Deputies:

1. A Deputy for Scientific Research Development Affairs: (Prof. Dr. Ali Shams ElDin)

Who is in charge of the overall management for planning and coordinating multiple research teams and development activities and processes at a research and development unit/group level that will eventually lead to the international recognition of our Department that will in turn participate in the International recognition of Kasr Al-Ainy Faculty of Medicine. This Deputy together with a team of representatives of each specialty is responsible for the validation of all the MSc & MD protocols before they are officially registered.

2. A Deputy for Teaching, Training & Staff Re-location: (Prof. Dr. Azza Mostafa)

Who is in charge of managing the teaching & training package that encompasses both these elements in order to maintain a motivated and skilled workforce and to fulfill the needs of the organization. This Deputy is also in charge of the relocation of staff to & from labs according to the need.

3. A Deputy for Examination Affairs: (Prof. Dr. Safaa Al-Karaksy)

Who is in charge of managing and liaising with the heads of the units all the matters related to the examinations including schedules, exam development & examination boards formation.

Chair  of  the  Clinical  &  Chemical  Pathology  Dept    

Deputy  for  ScienHfic  Research  Affairs  

Team  with  representaHves  of  

all  specialHes  

Deputy  for  Teaching,  

Training  Staff  PosiHoning  &  relocaHon  Affairs  

Team  with    representaHves  of    

all  specialHes  

Deputy  for  ExaminaHon  

Affairs  

Team  with    representaHves  of    

all  specialHes  

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2. Seniors of each Division The Department has 4 specialties and accordingly 4 seniors:

· Prof. Dr. Safaa Al-Karaksy: Senior Immunologist

· Prof. Dr. Hanaa Arnaout : Senior Hematologist

· Prof. Dr. Amani El-Kholy: Senior Microbiologist

· Prof. Dr. Fatma El-Mougy: Senior Chemical Pathologist

4. Secretary General for the Council of the ClinChem Department & Technical Development Officer (Dr. Nelly Abulata) As the Secretary General of the Council she moderates the Council and several Departmental Committees. And as the Technical Development Officer she collaborates with Laboratory Managers, Heads of Laboratories, Heads of Units and other Project Managers in the restructuring of the organizational system, developing decentralization and defining job responsibilities within the Department aiming to ensure that the objectives and performance plans of the Department and Faculty were being met. She also monitored, analyzes, evaluates, proposed solutions and reports on ongoing program, operational issues and projects under development 5. Executive team (2011-2012) Is composed of the Laboratory Directors (Administrative affairs), the Heads of Labs & Heads of Units (Technical Affairs) that direct, supervise and coordinate the functions and activities of the Hospital laboratories

Main Lab at Manial Hospital Laboratory Head of

Lab. (Technical)

Lab Director (Administrative)

Head of Hematology Unit

Head of Immunology Unit

Head of Genetics unit

Head of the Molecular Unit

Head of Microbiology Unit

Manial Clinical Pathology Lab.

Prof. Dr. Mervat Al-Ansary

Prof. Dr. Mona Salah

Prof. Dr. Naguib Zoheir

Prof. Dr. Mervat Al-Ansary

Prof. Dr. Hala Farawela

Prof. Dr. Mona Salah

A. Prof. Dr. Nada Nawar

Laboratory Head of Lab. (Technical)

Lab Director (Administrative)

Head of Trace Elements Unit

Head of Chemistry Routine Unit

Head of Proteins Unit

Head of Hormones Unit

Manial Chemical Pathology Lab.

Prof. Dr. Fatma El-Mougy

Prof. Dr. Badawy Al-Khouly

Prof. Dr. Badawy Al-Khouly

Prof. Dr. Lamia Mansour

Prof. Dr. Sahar Abdel-Atty

Prof. Dr. Nadida Gohar

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Other Hospital based labs

Laboratory Head of Lab. (Technical)

Lab Director (Administrative)

Head of Hematology

Head of Immunology

Head of Microbiology

Head of Chemical Pathology

Internal Medicine Hospital Lab.

Prof. Dr. Sahar Kamal

Dr. Magda Negm Prof. Dr. Sahar Kamal

Dr. Mohamed Abdullah

A. Prof. Dr. Nahla Fawzy

Japanese Hospital Lab.

Prof. Dr. Hanaa Arnaout

Prof. Dr. Iman Mansour

Prof. Dr. Hanaa Arnaout

Dr. Rabab ElHawary

A. Prof. Dr. Mona Mohie El-Din

Prof. Dr. Ola El-Sissy

Abou-Elrish Mounira Hospital Lab.

Prof. Dr. Hala Gabr

Prof. Dr. Azza Abou El-Enian

Prof. Dr. Hala Gabr

Prof. Dr. Maha Gaafar

Dr. Hanan Medany

Specialized Hospital Lab. (4th floor)

Prof. Dr. Taysir Eyada

Dr. Sheriene Abdel-Kader

Prof. Dr. Hanaa Arnaout

A. Prof. Dr. Aya Nassef

Prof. Dr. Walaa Gad

Prof. Dr. Iman Mandour

French Hospital Lab.

Prof. Dr. Laila Hegazy

Dr. Hanan Ibrahim

Prof. Dr. Nabiel El-Danasoury

Prof. Dr. Nancy ElGuindy

Prof. Dr. Amani El Kholy

Prof. Dr. Hazem Abou Youssef

King Fahd Hospital Lab.

A. Prof. Dr. Manal Kamal

Psychiatric Hospital Lab.

Prof. Dr. Badawy Al-Khouly

New ER Hospital Lab

Prof. Dr. Badawy Al-Khouly

Maternity Hospital Lab.

Prof. Dr. Iman Mandour

A. Prof. Aya Nassef

TBD TBD Prof. Dr. Iman Mandour

Sharm ElSheikh Int. Hosp.

Assistant Prof. Mohamed Shehata

Blood Bank Prof. Dr. Mervat Al-Ansary

Dr. Sahar Azab

Unit Closed and work is referred to the main lab or nearest specialized lab

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6. Executive Committees 1. Executive Committee for Laboratory Affairs: As things evolved over time, we found that it was necessary to form an Executive Committee, which has been meeting every month for the past couple of months usually one week prior to the Board meeting of the Department. At those meetings, the Executive Committee reviews the major issues facing the Department, weighing pros and cons and making preliminary decisions, to be ratified by the Board as a whole at the actual Board meeting of the Department. The Committee is comprised of: 1. The Chair of the Department: Prof. Safaa Al-Karaksy 2. The Head of the Laboratories

· Prof. Safaa Al-Karaksy · Prof. Taysir Eyada . Prof. Mervat Al-Ansary · Prof. Fatma El-Mougy · Prof. Hanaa Arnaout · Prof. Laila Hegazy · Prof. Azza Abou ElEnein . Prof. Sahar Kamal · A. Prof. Manal Kamal

3. The Laboratory Directors · Prof. Badawy Al-Kholy · Prof. Mona Salah · Prof. Hala Gabr · Prof. Iman Mansour · Dr. Magda Negm · Dr. Sahar Azab · Dr. Sherine Abdel-Kadr

2. Executive Committee for Blood Bank Affairs: Since the Department is responsible for the Technical supervision of the Blood Bank an Executive Committee for the Blood Bank has also been formed which will review and discuss any issues facing the Blood Bank. The Committee will start meeting on monthly basis starting from next month, typically one week prior to the Hospital Board meeting. The Committee is comprised of:

1. The Chair of the Department (Prof. Safaa Al-Karaksy) 2. The Head of the Blood Bank (Prof. Mervat Al-Ansary) 3. The Blood Bank Director (Dr. Sahar Azab) 4. The Deputy Head of the General Hospitals 5. Other members (to be determined).

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V- LABORATORY SERVICES WE PROVIDE

1. Background information:

Our Laboratories provide an extensive menu of routine & specialized laboratory tests to the patients who seek care at Kasr Al-Ainy Hospitals.

Lab Divisions

· Hematology Laboratory

· Clinical Immunology & Molecular Diagnostics

· Clinical Microbiology

· Clinical Chemistry

. Blood Bank

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2. Annual Productivity:

Hospital Lab

Relevant Hospital Info Total

Annual

Lab

Productivity

% out of the total

annual Productivity of

all labs

Inpatient

beds

Average Outpatients clinic cases per month

Average ER cases per month

Manial Labs

2,018 40,980 15,067 1,888,911 40%

French Lab

1,200 Not available

Not available

1,058,813 22%

Japanese Lab 421 8700 4,876 595,5114 12%

Internal Medicine Lab.

357 2175 1,268 550,338 11%

Abou El-Rish Lab

307 23,477 8,539 363,137 8%

4th floor Lab 277 No Clinic 180 170,949

4%

King Fahd Lab 111 514 No ER 142,291 3%

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40%  

22%  

12%  

11%  

8%  4%   3%  

%  out  of  the  total  annual  producHvity  of  2011  

Manial  

French  

Japanese  

Internal  Medicine  Abou  ElRish  

(318)  4,598,604  

(142)  1,888,911  

(65)  1,058,813   (16)  

595,114   (24)  550,338   (30)  

363,137  (24)  

170,949  (2)  

142,291  

0  

1,000,000  

2,000,000  

3,000,000  

4,000,000  

5,000,000  

6,000,000  

Total     Manial   French   Japanese   Internal  Medicine  

Abou  ElRish  

4th  floor   King  Fahd  

Total  no.  of  tests  &  Doctors    

Laboratory  

2011  Annual  producHvity  

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3. Productivity per Lab 1. Al-Manial Clinical & Chemical Pathology Labs:

We have 2 labs at Al-Manial Hospitals one on the ground floor (Clinical Pathology) and one on the 2nd floor (Chemical Pathology) with a total no. of employees of 349.

The Clinical Pathology Laboratory employs 150 people; 45 Faculty Staff (11 Emeritus Professors, 15 Professor, 7 Assistant Professors , 5 Lecturers, 4 Assistant Lecturer & 3 Demonstrators), 2 Specialists, 7 Residents, 14 Technologists, 43 Technicians, 6 Nurses, 18 Administration & 16 Cleaners.

The Chemical Pathology Laboratory employs 199 people; 88 Faculty Staff (9 Emeritus Professors, 15 Professor, 16 Assistant Professors , 22 Lecturers, 18 Assistant Lecturer & 8 Demonstrators), 2 Specialists , 4 Residents, 18 Technologists, 59 Technicians, 3 Nurses, 6 Administration & 17 Cleaners.

383,474  

39,596   15,319   591  

1,446,747  

1,888,911  

0  

200,000  

400,000  

600,000  

800,000  

1,000,000  

1,200,000  

1,400,000  

1,600,000  

1,800,000  

2,000,000  

Hematology  Tests  

Immunology  Tests  

Microbiology  Tests  

Parasitology  Tests  

Chemistry  tests   Total  no.  of  Tests  

Manial  Labs  

15

2. Japanese Lab:

The Laboratory employs 66 people; 12 Faculty Staff (1 Emeritus Professor, 5 Professor, 2 Assistant Professors, 3 Lecturers & 1 Assistant Lecturer), 4 Residents, 2 Technologists, 41 Technicians, 7 Administration & 1 Cleaners.

3. Abou El-Rish Lab:

The Laboratory employs 70 people; 16 Faculty Staff (4 Professor, 4 Assistant Professors , 2 Lecturers, 4 Assistant Lecturer & 2 Demonstrators), 6 Specialists, 8 Residents, 10 Technologists, 11 Technicians, 10 Administration, 3 Nurses & 6 Cleaner

104,236  19,701   8,010   7,827  

427,840  

595,114  

0  

100,000  

200,000  

300,000  

400,000  

500,000  

600,000  

700,000  

Hematology  Tests  

Immunology  Tests  

Microbiology  Tests  

Parasitology  Tests  

Chemistry  tests  

Total  no.  of  Tests  

Japanese  Lab  

68,813  

12,121   17,408   20,016  

244,789  

363,136  

0  

50,000  

100,000  

150,000  

200,000  

250,000  

300,000  

350,000  

400,000  

Hematology  Tests  

Immunology  Tests  

Microbiology  Tests  

Parasitology  Tests  

Chemical  Pathology  Tests  

Total  no.  of  Tests  

Abou  El-­‐Rish  Lab    

16

4. Internal Medicine Lab:

The Laboratory employs 55 people; 17 Faculty Staff (4 Emeritus Professor, 1 Professor, 5 Assistant Professors , 2 Lecturers, 4 Assistant Lecturer & 1 Demonstrator), 3 Specialists, 4 Residents, 10 Technologists, 15 Technicians, 4 Administration & 2 Cleaners.

5. 4th floor Lab: The Laboratory employs 64 people; 11 Faculty Staff (2 Emeritus Professors, 5 Professor , 3 Assistant Professors, 1 Lecturers), 3 Specialists, 10 Resident Specialists, 11 Technologists, 11 Technicians, 9 Administration, 4 Nurses & 6 Cleaners.

58,757  4,299   845   3,391  

483,228  

550,338  

0  

100,000  

200,000  

300,000  

400,000  

500,000  

600,000  

Hematology  Tests  

Immunology  Tests  

Microbiology  Tests  

Parasitology  Tests  

Chemistry  tests  

Total  no.  of  Tests  

Internal  Medicine  Lab  

41,282  

4,363   3,129   3,049  

119,096  

170,949  

0  

20000  

40000  

60000  

80000  

100000  

120000  

140000  

160000  

180000  

Hematology  Tests  

Immunology  Tests  

Microbiology  Tests  

Parasitology  Tests  

Chemistry  tests  

Total  no.  of  Tests  

4th  Floor  Lab  

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6. King Fahd Lab: The Laboratory employs 20 people; 1 Faculty Staff (1 Professors), 1 Specialists, 6 Technologists, 5 Technicians, 5 Nurses, 1 Administrative Secretaries & 1 Cleaner.

7. French Lab The Laboratory employs 252 people; 59 Faculty Staff (3 Emeritus Professor, 15 Professor, 9 Assistant Professors, 17 Lecturers, 15 Assistant Lecturer), 5 Senior Registrars, 26 Technologists, 77 Technicians, 6 Nurses, 59 Administration & 19 Cleaners

23,107  11,205  

1,979   3,908  

102,088  

142,291  

0  

20000  

40000  

60000  

80000  

100000  

120000  

140000  

160000  

Hematology  Tests  

Immunology  Tests  

Microbiology  Tests  

Parasitology  Tests  

Chemistry  tests  

Total  no.  of  Tests  

King  Fahd  Lab  

166,702  36,943   15,461   28,573  

811,134  

1,058,813  

0  

200000  

400000  

600000  

800000  

1000000  

1200000  

Hematology  Tests  

Immunology  Tests  

Microbiology  Tests  

Parasitology  Tests  

Chemical  Pathology  

Tests  

Total  no.  of  Tests  

French  Lab  

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4. Productivity per division

5. Blood Bank Services

· Blood Bank Profile: The Blood Bank employees approximately 128 people who are involved in Blood Donation, Blood Processing and Hemapheresis.

· Blood Bank Structure: • The Head of the Blood Bank: Prof. Dr. Mervat Al-Ansary • Administrative Director: Dr. Sahar Azab. • The Team includes: 7 Specialists , 2 Residents, 6 Financial officers , 2 Administrative

Officers, 2 Social Officers, 1 Statistician, 5 Technologists, 30 Technicians, 35 Nurses, 7 Administrative Secretaries, 11 Clerks, 22 Cleaners

. Blood Donation during 2011

. Blood issued during 2011 Type of Patient No. of Units Inpatient Departments 49,779 OR & ER 13,420 External 2,379 Total no of Units issued 65,578

18%  

3%  

1%  

78%  

Hematology  

Immunology  

Microbiology  

Chemical  Pathology  

Venue of Donation No of Units Outpatient-clinic 21,235

Donation campaign 30,229 Total no of Units 51,464

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VI- 2011 ACTIVITIES & ACCOMPLISHMENTS 1- Scientific Research

· Project Profile: The aim of this project is to develop a plan for the Research activities of the Department over the coming 2-5 yrs (2009- 2013) which will involve all the specialties of the Department. The project will hopefully lead to the international recognition of the Department that will in turn participate in the International recognition of Kasr Al-Ainy Faculty of Medicine . Project starting date: 27/08/09 · Project structure: Project Leader: Prof. Ali Shams El-Din Project Team Members: Prof. Azza Mostafa, Prof. Taghrid Gaafar, Prof. Amani El-Kholy, Prof. Fatma El-Mougy, Prof. Mona Wasif, Prof. Hala Farawela, Prof. Afaf ElBannah, Prof. Iman Mansour, Prof. Hala Ali, Prof. Hala Gabr, Prof. Sahar Abdel Atty Ethical committee Members: Prof. Azza Mostafa, Prof. Dr. Safaa Al-Karaksy, Prof. Amani El-Kholy, Prof. Fatma El-Mougy Key research subjects 1. HCV 2. Stem Cell Research 3. Neurodegenerative diseases 4. Infection prevention and control 5. Molecular basis of Hematological disorders 6. Juvenile Diabetes Mellitus. . Accomplishments to date: 1. Planning process: Done 2. Implementation: Done 3. Follow: in process . Research Awards: 1. Prof Heba Abdel Razik has won the National Egyptian Promotional 2011 Award 2. Prof Heba Abdel Razik has won the Cairo University Encouragement 2011 Award

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. Research Grants/ Projects : 1. STDF grant: "Phase I-II clinical trial autologous dendtritic cell vaccine in patient with acute myeloid leukemia in remission. Principle investigator: Prof. Dr. Mervat Al-Ansary 2. Cairo University Grant: "Study of the pluripotent stem cell potential of Peripheral blood mononuclear cells ". Principal Investigator Prof. Dr. Mervat Al-Ansary 3. Cairo University- NAMRU-3 project: “Study of the sentinel surveillance for severe respiratory illness (SARI) Project Manager: Prof. Dr Amani El Kholy 4. Cairo University, NAMRU-3, USAID & Cornell University National project: “ Quality improvement and patient safety Project Coordinator: Prof. Dr Amani El Kholy

. 2011 International publications

1. Tamer Saied, Amany El kholy, Soad F. Hafez, Hadia Basim, Momtaz O. Wasfy, Waleed El-

Shoubary, Ahmed Samir, Guillermo Pimentel and Maha Talaat. Antimicrobial Resistance in Pathogens causing Nosocomial Bloodstream Infections in University Hospitals. Am J Infect control (3.077).

2. Amani El Kholy, Mariam Younan. Prospective study of healthcare- associated bloodstream infections in pediatric intensive care units in Cairo University Hospitals. Arab Society for Laboratory Medicine.

3. Mervat El-Ansary, Iman Abdel-Aziz, Sherif Mogawer, Samah Abdel-Hamid, Olfat Hammam, Salwa Teaema, Marwa Wahdan. Phase II Trial: Undifferentiated Versus Differentiated Autologous Mesenchymal Stem Cells Transplantation in Egyptian Patients with HCV Induced Liver Cirrhosis. Stem Cell Rev and Rep (IF 3.76)

4. Nermeen Ahmed El Desoukey, Reham Abd Aleem Afify, Dalia Gamil Amin, and Rasha Faragaly Mohammed. CD200 Expression in B-Cell Chronic Lymphoproliferative Disorders. Journal of Investigative Medicine (IF 1.536).

5. El-Sayed SZ, El-Kheir WA, Gabr H, Gomaa AA, El-Noomani N, Hegazy M. Amer ME. Clinical and laboratory evaluation of patients with end-stage liver cell failure injected with bone marrow-derived hepatocyte-like cells. Eur J Gastroenterol Hepatol (IF 1.598).

6. Gabr H, Hedayet A, Imam U, Nasser M Limb salvage using intramuscular injection of unfractionated autologous bone marrow mononuclear cells in critical limb ischemia: a prospective pilot clinical trial. Exp Clin Transplant (IF 0.6)

7. Zaghloul S, Zickri M,Abd El Aziz D, Mabrouk D, Gabr H. Effect of stem cell therapy on amiodarone induced interstitial lung fibrosis in albino rats. Int J Stem Cells.

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8. Gabr, Hala; Ghannam, Osama; Awad, Mohamed Reda; von Wild, Klaus; El-Kheir, Wael Abo; Ewes, Ibrahim. Autologous Mesenchymal Stem Cell Therapy for Spinal Cord Injury: Long Term Safety and Clinical Efficacy. American Journal of Neuroprotection and Neuroregeneration

9. Aly H, Mohsen I,Badrawi N, Gabr H, Ali Z, Akmal D. Viability and neural differentiation of mesenchymal stem cells derived from umbilical cord following perinatal asphyxia. Journal of Perinatology (IF 2.003)

10. Manal Kamal and Waleed El-Khayat. Do Serum Angiopoietin-1, Angiopoietin-2 and Their Receptor Tie-2 and 4G/5G Variant of PAI-1 Gene Have a Role in the Pathogenesis of Preeclampsia? Journal of Investigative Medicine (IF 1.536).

11. Manal Kamal, Mona M Fathy, Eman Taher, Manal Hasan, May Tolba. Assessment of the role of paraoxonase gene polymorphism (Q192R) and paraoxonase activity in the susceptibility to atherosclerosis among lead-exposed workers. Annals of Saudi Medicine (IF 0.697)

12. Naguib M. Zoheir, Mona S. Hamdy, Mervat M. Khorshied, Nelly N. Abulata, Mehry El Sobky, Amr M. Saleh, Hussein M. Khairy. Association of C46T genetic polymorphism of coagulation factor XII with deep venous thrombosis: a cohort study on Egyptian patients. Comp Clin Pathol (IF 0.33)

13. Hoda Ali Sadek, Wafaa Hassan El-Metnawey, Iman Abdel-Mohsen Shaheen, Mervat Mamdouh Korshied, Azza Sobieh Mohamed. Quantitative Assessment of Wilms Tumor 1 (WT1) Gene Transcripts in Egyptian Acute Lymphoblastic Leukemia Patients. Journal of Investigative Medicine. (IF 1.536).

14. Azza Ibrahima, Hala Abdel Rahmana, Mervat Khorshieda, Rania Samia, Nelly Nasra, Ola Khorshid. Tumor necrosis factor alpha−308 and Lymphotoxin alpha+252 genetic polymorphisms and the susceptibility to non-Hodgkin lymphoma in Egypt. Leuk Res (IF 2.3)

15. Menat Allah Kamal El Deen, Mervat M. Khorshied, Zeinab A. El Sadani, Yasmine M. Amrousy,

Nermeen M. Galal.Mannose binding lectin (MBL2) gene polymorphism in sickle cell anaemia: an Egyptian study". Comp Clin Pathol (IF 0.33)

16. Manal W. El-Masry, Mervat M. Khorshied Iman A. Shaheen, Nelly N. Abulata & Tarek A. Hashem. Flow cytometric detection of leukemic stem cells (LSCs) in Egyptian pediatric B-acute lymphoblastic leukemia.. Comp Clin Pathol. (IF 0.33)

17. Abdelrazik Heba, Spaggiari Gm, Chissone L, Moretta L. Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T and NK cell proliferation and function. Eu .J. Immun (IF 4.942)

18. Lupu M., Khalil M, loradache F, Andrei E, Pfannkucke K, Spitkovsky D, Baumgartner S,

Rubach M, Abdelrazik H, Buzila C, Brockmeier K, Simionescu M, Hescheler J, Maniu H. Direct contact of umbilical cord endothelial progenitors with living cardiac tissue is a requirement for vascular tube-like structures formation. J Cell Mol Med (IF 4.608)

19. Eman Abdul Rahman and Mona Wassef: Evaluation of the chromogenic Cica-a-test for detecting extended spectrum and AmpC a-lactamases among cefoxitin-resistant isolates. Lab Med

20. Eman Abdul Rahman and Rasha ElSherief; High rates of Intestinal Colonization with extended spectrum B-lactamase producing Enterobacteraiciae among healthy individuals. Journal of Investigative Medicine (IF 1.536)

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21. Hala Gabr Metwally, Raafat Abd ElFattah, Dina Ahmed, Marwa Farhan, Somaia M. Mousa; Mesenchymal stem cells derived from bone marrow and leukaphersis show different putative subpopulations. Stem cell studies

2- Promotions: 1. Promoted to Professor • A. Prof. Nancy El-Guindy • A. Prof. Heba Abdel Razik • A. Prof. Nermine ElDessouky

2. Promoted to Assistant Professor

• Dr. Inas Hamdy • Dr. Samah Abdel Hamid • Dr. Iman AbdelMohsen • Dr. Asma Abdel Aal • Dr. Dalia Labib • Dr. Hanan Madany • Dr. Riham Affify • Dr. Asma Abdel Aal • Dr. Manal Makhlouf • Dr. Riham ElEssawy

3. Promoted to Lecturer

• Dr. Nahed Ibrahim • Dr. Rabab ElHawary • Dr. Rania Darwish • Dr. Gehan Shahin • Dr. Nermine Magdy

3- Quality Assurance for Laboratory service

. Project profile: The aim of Quality assurance project (QA) is to ensure that the Laboratories of Cairo University Hospitals provide services that meet the best quality standards. . Project starting date: 27/08/09 . Project Structure: Project Leader: Dr. Ola Khashaba Project Team Leaders (2009-2011) : Prof. Safaa Al-Karaksy (Immunology), Prof. Naguib Zoheir (Hematology), Prof. Mona Wasif (Microbiology),Prof. Lamiaa Mansour (Chemical Pathology) Project Team Members: Relevant staff members in each team. . Accomplishments during 2009-2011 at Main Laboratories: 1. Team re-building 2. Awareness & Training sessions: For doctors 3. Follow up of the implementation of the previously developed forms in all relevant previously

mentioned departments with varying degree of compliance. 4. In addition to random audits which were performed through informal communication with the

process owners as one way of improving their performance the last one performed on 03/10/2011.

5. Proficiency testing was partially established in some hematologic tests as a means of external quality control.

6. Work is in progress to fully implement the intranet through which the quality control will be automated.

7. Work is in progress to teach doctors in charge of developing and interpreting the control charts.

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8. Training sessions and meeting with the new teams are regularly held almost once weekly. 9. Most of the team members regularly attend the meetings and most of them shared in the

process of cross-auditing and presented their work to the Chair of the Dept. 10. Most of the Department have SOPs either written or as product insert.

4- Quality Assurance for Education

· Project Profile: The aim of this project is to check how well the Department meets it’s responsibilities, identifies good practice and makes recommendations for improvement. . Project starting date: 1/10/10 · Project structure: Project Leader: Prof. Hala Sheebah Project Coordinator: A. Prof Mervat Khorshied Project Team Members: Prof. Hala Ali, Prof. Nehad Mosaad, A.Prof. Maha Gaafar, A.Prof. Aya Nassef, A. Prof Mervat Khorshied, Dr. Safa Meshaal, Dr. Rania Darwish, Dr. Safaa ElGabarty . Accomplishments to date: 1. Documentation of the Lab teaching materials & Lab infrastructure. 2. Documentation of the publications of the Faculty. 3. Documentation of the Research projects/ grants that Faculty is involved in. 4. Course Specifications. 5. Documentation of the teaching schedules and examinations. 6. Follow up & evaluation procedure for the teaching & training programs.

5- Training courses/ workshops: • Training course for “Screening metabolic disorders by Tandem Mass Spectrometry” Organized

via a collaboration between the Chemical Pathology team (Prof. Dr. Fayza A Hassan Prof. Dr. Fatma El-Mougy Prof. Dr. Sahar Abdel-Atty Prof. Dr. Iman Mandour A. Prof.Dr. Marian Morgan Dr. Dina Mehaney Dr. Mohammed A. Monem) and the Pediatric Endocrinology team at Pediatric Hospital

• 2 workshops Lead Prof. Amani Al-Kholy & her Infection Control Team (A.Prof. Mervat Gaber Al-Anainy, A.Prof. Mona Mohieddin Abdel Halim, Dr. Mariam Adel, A. Lecturer Mai Sherief) in collaboration with:

1. NAMRU-3 on: Practical Approach to prevention of Healthcare associated infections in Cairo University Hospitals

2. NAMRU-3, USAID, CDC and Cornell University on: Advanced training on Infection prevention and control

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6- ClinChem Conferences The Department held 3 very successful Scientific Conferences 2010-2011. The 1st CLINCHEM 2010 Conference" Molecular Biology: Into the future" held from 31st of March -2nd of April at CICC had a record-breaking attendance of nearly 600 participants in the could not have been achieved without the support of sponsors like SIEMENS,EL-DAWLEYA,TECHNOSCIEN, CLINILAB,ETICO,ENDOMEDIX&ULTRADIAGNOSTICS. I n response to the feedback we received from our attendees and sponsors we decided to launch the 2nd CLINCHEM 2010 Conference "Transfusion Medicine & Quality updates: Revolution not evolution" that was held on the 24th of October, 2010 at the Learning Resources center at Kasr Al-Ainy Faculty of Medicine, Cairo University which was another great success thanks to sponsors such as DIA MED, FUTURE HORIZON, SPECTRA, SIEMENS & INTERPHARM. Another source of pride was that the Department held a third very successful Conference; 3rd CLINCHEM 2011 “Genetics and Tissue Engineering”, which was held at the Cairo International Conference Center from 3rd - 5th of April, 2011.

The Department is building on an extraordinary legacy and we plan to make it a yearly event. There is also a collaborative initiative with the Egyptian Society of Laboratory Medicine regarding their upcoming Conference that will be held during April 2012.

3rd ClinChem Conference; CLINCHEM 2011 ““Genetics and Tissue Engineering ": 3rd -5th of April at Cairo International Conference Center General info

Conference President Prof. Ahmed El-Saifi

Vice President Prof. Fatma El-Mougy

Secretary General Prof. Ezzat ElSobky Prof. Mervat Al-Ansary

Conference Coordinator Dr. Nelly Abulata

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Organizing Committee

Hematology Committee Prof. Azza Mostafa A. Prof. Mervat Khorshied A. Prof. Heba Gouda

Microbiology Committee Prof. Mona Wassef Prof. Dr. Nevine ElRasheedy Prof. Maha Gaafar

. Immunology/ Genetics Committee Prof. Safaa Al-Karaksy Prof. Hala Farawela A. Prof. Solaf Mohamed A. Prof. Aya Nassef

Chemistry Committee Prof. Sahar Abdel Atty Dr. Heba El-Baz Dr. Riham El-Sayed

Scientific Program Committee

Hematology Committee

Prof. Ali Shams ElDin Prof. Azza Ahmed Prof. Tayssir Eyada

Microbiology Committee

Prof. Walaa Gad Prof. Souhair Helal Prof. Amani Al-Kholy

. Immunology Committee Prof. Nawal Affifi Prof. Nehad El-Sheemy Prof. Taghrid Gaafar

Chemistry Committee Prof. Omar Al-Roubi Prof. Omnia Youssef Prof. Fayza Abdel Hamid

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ORGANIZING COMMITTEE

PANEL

AUDIENCE

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6- Website expanded & updated (http://www.clinchemcairo.org) The website for the Clinical & Chemical Pathology Department has expanded and updated The list of lab tests is now available on the Laboratory service page, the Teaching & Training page will include the Curricula & teaching schedules and the Faculty page includes all the names of the Faculty and soon will have their CVs added to them very soon. Annual Progress Report for 2011 will be added to the homepage.

Home About us Laboratory Services Projects Teaching &Training Faculty Events Contact us

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Please contact us for additional information about our Department.

Contact the Chair's Office

2011 Annual Progress Report

2010 Annual Progress Report

2009 Annual Progress Report