Canadian Transplantation Highlights1956: Heart valve* transplants are performed in Toronto, Ontario.1958: First successful kidney transplant, between identical twins, is performed at the Royal Victoria Hospital in Montreal, Quebec.1963:First kidney transplant from a deceased donor is performed in Montreal, Quebec.1968:First heart transplant is performed in Montreal, Quebec.1970:First liver transplant is performed in Montreal, Quebec.1974:First pediatric bone marrow transplant is performed in Toronto, Ontario.1983:First heart-lung transplant is performed at the University Hospital in London, Ontario. Successful single lung* transplant is performed at the Toronto General Hospital in Ontario. 1986:Successful double lung* transplant is performed at the Toronto General Hospital in Ontario.1988:Successful liver-bowel* transplant is performed at the University Hospital in London, Ontario.1989:Islet cells are transplanted into a patient with diabetes at the University of Alberta Hospital in Edmonton.1993:First living-related (parent to child) partial liver transplant is performed in London, Ontario.1995:In Montreal, Quebec, pig liver tissue is used as a bridge to keep a patient alive until a human liver became available for transplant.1997:The London Health Sciences Centre in Ontario transplants a liver, bowel, stomach, and pancreas into a five-month-old infant – the world's youngest recipient of a multi-organ transplant.2000:First adult-to-adult living liver transplant is performed in London, Ontario.2004:First live kidney donor transplant from an anonymous donor to an unrelated recipient is performed in Vancouver, British Columbia.

*A world first

2015 Joint Meeting A Triumph of Canadian Innovation and Cooperation, Like 1983!

The Banff ProcessConsensus communication in renal transplantation

a

The Banff lesions g, i, t, v - score

The Banff communityPathologistsNephrologistsTx-SurgeonsLab-Medicine

The Banff communityPathologistsNephrologistsTx-SurgeonsLab-Medicine

established by

consensus in 1991

The Banff classificationCurrent consensus for diagnostics

The Banff classificationCurrent consensus for diagnostics

moderated

Banff meetingsthesis-antithesis-synthesis

tentative

thresholds

participate

refinementBanff Working Groups

Feedback concerning weaknesses and strengths by results from independent research

New membersBiostaticiansMolecular Biologists“Omics”-specialists

New membersBiostaticiansMolecular Biologists“Omics”-specialists

Off-springsLiverPancreasLung, HeartCTA

Off-springsLiverPancreasLung, HeartCTA

• 1991 First Conference• 1993 First Kidney International publication• 1995 Integration with CADI • 1997 Integration with CCTT classification• 1999 Second KI paper. Clinical practice guidelines. Implantation biopsies.• 2001 Classification of antibody-mediated rejection (ABMR): Regulatory agencies participating• 2003 Genomics focus, ptc cell accumulation scoring• 2005 Gene chip analysis. Elimination of CAN, identification of chronic antibody-mediated

rejection.• 2007 First meeting far from a town called “Banff” – La Coruna, Spain.• 2009 Working groups. Meeting in Banff, Alberta, Canada • 2013 Establishment of Banff Foundation for Allograft Pathology and recognition of C4d-

negative ABMR

BANFF Classification - Milestones

Significance of ‘Banff papers’• 4244 citations of the 9 Banff meeting reports• 790 Banff / Transplantation papers in PubMed• Banff 2003 meeting report (ABMR criteria) = most cited AJT paper• 3 Banff meeting reports are among the top 4 cited AJT articles

Dunbar’s Number of 150 People You Can Have Significant Empathetic Friendships With. Need to Maintain This

Intimate Feeling in A Larger Meeting of 600.

Steven Paraskevas, MD, PhDPresident CST

8

CST is…

• THE multidisciplinary professional organization of Canada’s organ donation and transplantation community.

• An association comprising close to 700 members and associate members• A professional NFP with longstanding ties to international partner

organizations• A dynamic player in the OTDT landscape continually re-evaluating its

relationship with agencies its own members helped lobby to create• Now in its 35th year• A longstanding affiliate of the TTS

9

10

Teaching, education and professional

development

Developing consensus, best practices and

expert opinion

Fostering research and knowledge creation

• CST meeting has grown to showcase research from across Canada and around the world• Joint symposia with other societies: AST, CSN, CSI• Webinar series with the Transplantation Society• 2013 CST successfully negotiated the designation of SOT as an Area of Focused Competence within the Royal College• CST sponsors multiple annual training awards• The CST ASM is the principal venue for networking among the SOT and HLA specialties• CST is represented in all major committees at CBS• Special interest groups of our membership have always held annual or semi-annual networking/priority setting

meetings during the ASM: Kidney, Liver, Pancreas/Islet, Lung, Heart, Pediatric, Pharmacy, Allied Health, HLA, Donation• Canadian National Transplant Research Program (CNTRP) holds group meeting at the ASM, as well as showcasing its

annual achievements

Joint Banff/CST Program Committee

Co-chairs: Dr. Alexandre Loupy and Dr. Prosanto

Chaudhury

2015 Banff/CST Meeting Organizing Corporation (“2015 MOC”) – Co-Directors: Dr. John Gill, Dr. Michael Mengel

Members: Anthony Jevnikar, David Rush, Denis Glotz, Kim Solez, Marcelo Cantarovich, Mark Haas, Steven Paraskevas

Joint Banff/CST Finance Committee

Joint Program Structure 

Banff activies

 

Joint activities

   

CST activities

2015 CST / Banff meeting program

           

  Day 1: Monday Day 2: Tuesday Day 3: Wednesday Day 4: Thursday Day 5: Friday Day 6: SaturdaySession Potential Banff-premeeting Plenary Session: Progress Report

Banff Working groupsJoint Pleanary session I: Joint Pleanary session II: Concurrent sessions: Banff

meeting summary and CST symposia

 

08:00 - 08:30            08:30 - 09:00            09:00 - 09:30            09:30 - 10:00            

10:00 - 10:30 Coffee break Coffee break Coffee break Coffee break Coffee break Coffee break10:30 - 11:00            11:00 - 11:30            11:30 - 12:00            12:00 - 01:00 Working Lunch: Banff registration

openWorking Lunch: Working Lunch: CST registration

openWorking Lunch: Lunch: Banff adjourns Lunch:

Session Potential Banff-premeeting Concurrent Organ Sessions Concurrent sessions: Banff Organ sessions and CST Working groups

Concurrent sessions: Banff Organ sessions and CST symposia

 

 

01:00 - 01:30            01:30 - 02:00            02:00 - 02:30            02:30 - 03:00            03:00 - 03:30 Coffee break Coffee break Coffee break Coffee break Coffee break Coffee break 03:30 - 04:00            

04:00 - 04:30            04:30 - 05:00            05:00 - 05:30            05:30 - 06:00            Events            

6:30 Welcome Reception - Cocktails and snacks. Open bar

Case presentations from varioous organs with Wine Beer and Food

Joint Poster Session with reception CST Awards and Joint CST/Banff Gala Dinner

CST President's dinner  

Target Audience for the 2015 joint CST/Banff meeting: total ~600 expected international delegates

• Basic Scientists• Pathologists• Immunogeneticists and HLA experts• Transplant Physicians: Internal Medicine, Surgery,

Infectious Diseases, Critical Care• Allied Health Care• Students, Trainees, Fellows