2015 IACUC Conference Guide

Tuesday, March 17 • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • 12:00-5:00 PM Essentials of IACUC Administration Harbor Ballroom II

Wednesday, March 18 • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • 8:00 AM-5:00 PM Essentials of IACUC Administration Harbor Ballroom II

8:00 AM-5:00 PM IACUC 101TM: “The Basics” Grand Ballroom AB

5:00-6:30 PM Pre-Conference Programs Networking Reception Grand Ballroom Foyer

Thursday, March 19 • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • 7:00-8:00 AM Continental Breakfast to Welcome First-Time Attendees (pre-registration required) Grand Ballroom CD

8:00-8:15 AM Welcome from the Conference Co-Chairs Grand Ballroom AB

8:15-9:00 AM Keynote Address: Darin S. Carroll Grand Ballroom AB

9:00-10:15 AM Panel I: Structuring Your IACUC for Efficiency and to Facilitate Research Grand Ballroom AB

10:15-10:45 AM Coffee Break Grand Ballroom Foyer

10:45 AM-12:00 PM Didactic Sessions and Workshops Series A See schedule for room locations

12:15-1:30 PM Common Ground Networking Lunch Galleria Hall

1:45-2:30 PM Keynote Address: David K. Meyerholz Grand Ballroom AB

2:30-3:45 PM Panel II: Studies of Animals When They Are the Targeted Beneficiaries Grand Ballroom AB

3:45-4:00 PM Coffee Break Grand Ballroom Foyer

4:00-5:15 PM Didactic Sessions and Workshops Series B See schedule for room locations

5:15-6:30 PM 2015 IACUC Conference Welcome Reception Grand Ballroom AB & Grand Ballroom Foyer

Friday, March 20 • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •7:00-8:00 AM CPIA® Networking Continental Breakfast (pre-registration required) Grand Ballroom CD


8:15-9:00 AM Henry Spira Memorial Lecture: Frans B. M. de Waal Grand Ballroom AB

9:00-10:15 AM Panel III: Fallout from FOIA Grand Ballroom AB


10:45 AM-12:00 PM Didactic Sessions and Workshops Series C See schedule for room locations

12:15-1:15 PM Lunch Galleria Hall

12:15-1:15 PM Research Ethics Book Group Lunch and Book Signing with Author and

Henry Spira Memorial Lecturer Frans B. M. de Waal, PhD (pre-registration required) Grand Ballroom CD

1:30-2:45 PM Panel IV: Virtual IACUC: This Meeting Is in Session! Grand Ballroom AB


3:00-4:15 PM Didactic Sessions and Workshops Series D See schedule for room locations

4:15-4:30 PM Break

4:30-5:45 PM 2015 IACUC Conference Town Hall Meeting Grand Ballroom AB

5:45-6:45 PM Closing Reception Grand Ballroom Foyer

Schedule at a Glance

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CONFERENCE INFORMATIONWelcome from PRIM&R’s Executive DirectorWelcome from the Conference Co-ChairsAnnouncements ScholarshipsCPIA®

SCHEDULEPre-Conference ProgramsYour Guide to the Tracks Your Guide to the Conference ScheduleSchedule: March 19Schedule: March 20

FACULTYFaculty ListPlenary and Keynote Biographies

POSTERS

SUPPORTERS & EXHIBITORS

ABOUT PRIM&RBoard of Directors StaffThank You to Our 2015 Committee MembersHenry Spira Memorial Lecture

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1011121321

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3Rs reduction, replacement, refinement

AAALAC International Association for Assessment and Accreditation of Laboratory Animal Care International

AALAS American Association for Laboratory Animal Science

ACLAM American College of Laboratory Animal Medicine

APHIS Animal and Plant Health Inspection Service

ASLAP American Society of Laboratory Animal Practitioners

AWA Animal Welfare Act

CPIA® Certified Professional IACUC Administrator

FOIA Freedom of Information Act

Guide The 8th Edition of the Guide for the Care and Use of Laboratory Animals (NRC 2011)

IACUC institutional animal care and use committee

IBC institutional biosafety committee

NIH National Institutes of Health

OLAW Office of Laboratory Animal Welfare

PHS United States Public Health Service

PRIM&R Public Responsibility in Medicine and Research

USDA United States Department of Agriculture

VA United States Department of Veterans Affairs

Common Abbreviations and Acronyms

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Welcome from PRIM&R’s Executive Directorco

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prim&r’s 2015 institutional animal care and use committee conference

Dear Conference Attendees:Welcome to Boston and the 2015 IACUC Conference! Each year, PRIM&R strives to make its IACUC Conference a forum where animal care and use professionals meet to exchange ideas, learn best practices, and discuss and refine the ethical considerations involved in conducting responsible research with animals. In doing this, we look to create new opportunities to facilitate constructive and ongoing conversation on sometimes difficult topics, and to bring our community together. This year’s conference has two new components to advance those goals.

First, we introduced PRIM&R’s Principles and Expectations for Participation in Educational Programs and Conferences as part of our registration process. As this policy makes clear, PRIM&R is committed to being an impartial convener within the research ethics field. We value freedom of expression, constructive and respectful dialogue, and spirited discussion, essential as they are to finding common ground. It is important to us, and to you, that PRIM&R’s IACUC Conference provides a safe and respectful environment for you to increase your knowledge of best ethics and oversight practices and confer with peers and experts in a constructive way. You can read more about the policy on page 6 in this guide, and you will be reminded of its particulars at the beginning of the conference and each session. I know you value this time together as much as we do, and I hope this policy allows you to get the most you possibly can out of these two days.

Second, we are premiering Town Hall Meeting on the last afternoon of the conference. This session will cover a range of hot topics and challenging issues using input you’ll provide throughout the conference. We expect it to be a lively and energizing session, so I hope you attend and give us your feedback on the event in your evaluation.

But before that happens, though, there are three keynote addresses, four plenaries, and more than 60 breakout sessions developed specifically for you. As you will see in the pages that follow, the conference schedule covers emerging issues such as the fallout from FOIA, top deficiencies seen by federal regulators, retirement of research animals, the promotion of diversity within the animal care and use profession, and the reproducibility of results, as well as perennial topics such as protocol review, communicating to the public about animal research, and animal well-being and the 3Rs. I think you’ll find there’s something—a lot of somethings!—for everyone.

We wouldn’t be able to offer such a range of content without our incredibly hard-working Planning Committee. I offer my warmest thanks to co-chairs F. Claire Hankenson and Christian E. Newcomer, and to committee members: B. Taylor Bennett, Carol Clarke, Barbara A. Garibaldi, Melinda B. Hollander, Tanise

L. Jackson, Jori K. Leszczynski, Natalie L. Mays, Jon D. Reuter, Mary Jo Shepherd, Robert S. Sikes, Susan Silk, and Janet D. Stemwedel, all of whom generously volunteered their time and expertise to craft this exceptional program.

This meeting wouldn’t be possible without the support of several important partners. Thanks are owed to AAALAC international; NIH OLAW; USDA, APHIS, Animal Care; and the Edna H. Tompkins Charitable Trust.

I would also like to extend my thanks to the more than 120 conference faculty members and 17 poster presenters who over the next two days, will provide you the most current information, newest and best practices, and their professional expertise and wisdom, so that each of you might return to your home institutions ready and able to strengthen your research programs. We appreciate their leadership and many hours of careful preparation.

Finally, thank you for being here and demonstrating your commitment to advancing the responsible use of animals in research. It’s an exciting, but challenging, time to be involved in the research enterprise—budgets are tight, research technologies and methodologies are evolving, and the demands on your time seem to be never-ending.

Fortunately, you have come to the right place. In the days to come, you’ll attend thought-provoking and hands-on sessions, browse posters, visit with our supporters and exhibitors, network with colleagues, and seek expert advice. I encourage you to find the combination of activities that best addresses the challenges you face. And, if you have an idea for something you’d like to see at a future conference, please let us know by filling out your evaluations.

I wish I could be onsite with you. I recently gave birth to my first child, and so am away from the office for several weeks and missing this year’s meeting. I look forward to seeing you in 2016, though, and in the meantime, enjoy your meeting!

With best wishes,

Elisa A. Hurley, PhDExecutive Director

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Welcome from PRIM&R’s Executive Director

Each year, PRIM&R presents the IACUC Conference as a collegial place where animal care and use professionals can meet to exchange ideas, discuss best practices, and grapple with the complex ethical issues raised by research with animals. We’re confident the next two days will provide you with insight and inspiration, challenge you to think about the larger issues related to research ethics and animal care and use, offer you concrete tools to strengthen your knowledge and skills, and provide ample opportunities for networking with your colleagues from all over the world. We encourage you to make the most of this stimulating environment and the unique opportunities for dialogue, hard work, and fun offered here in Boston.

The crafting of this year’s program was a collaboration of 14 volunteers representing expertise from every corner of the field. This energetic, dedicated, hardworking—and always fun!—group was responsible for selecting three keynote speakers; designing five plenary sessions; planning more than 60 breakout sessions; identifying more than 120 faculty members; and reviewing numerous poster submissions. It was a substantial undertaking, and we believe it has paid off in a timely and robust program.

This year’s keynote speakers promise to inform and inspire. Darin S. Carroll, MS, PhD, acting branch chief, Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, will speak on animal research in emerging zoonoses. Frans B. M. de Waal, PhD, Charles Howard Candler Professor of Primate Behavior, Emory University; director, Living Links Center, Yerkes National Primate Research Center, and this year’s Henry Spira Memorial Lecturer, will discuss primate social intelligence. David K. Meyerholz, DVM, PhD, DACVP, DACVM, director of the division of comparative pathology and associate professor in the department of pathology at the University of Iowa Roy J. and Lucille A. Carver College of Medicine, will speak about the origins of cystic fibrosis. We are thrilled to have all three of these accomplished and engaging speakers with us.

New to the program this year, the final session of the conference will be a Town Hall Meeting, a group review of hot topics and challenging conundrums the audience ultimately will design from queries they submit throughout the conference. We are excited to feature this dynamic and interactive finale at the meeting, and invite you to submit any questions you have to the Help Desk until 12:15 PM on Friday, March 20.

Finally, we’re delighted to report that this year’s program features 14 breakout sessions derived from PRIM&R’s Call for Session Proposals. We received just over 30 ideas through this process, and we thank our community for taking the time to submit their proposals. In addition, we are proud to announce that 17 exemplary posters are being featured at this year’s event. Please stop by the poster gallery located in the Commonwealth Foyer to view this exciting and innovative work.

We rely on our community for fresh ideas and perspectives and the program is, without a doubt, stronger for these contributions. With this in mind, we encourage you to consider submitting a session proposal and/or poster abstract for the 2016 IACUC Conference. The Calls for Session Proposals and Poster Abstracts for 2016 are already open; please visit www.primr.org/iacuc16 for details.

So, welcome, once again, to the 2015 IACUC Conference. We hope you enjoy the meeting and return to your institutions with innovative strategies and strong collegial networks that can help you enhance your research programs.

Warmly,

F. Claire Hankenson, DVM, MS, DACLAMDirector, Campus Animal Resources; Attending Veterinarian; Professor, Laboratory Animal Medicine, Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University

Christian E. Newcomer, VMD, MS, DACLAMExecutive Director, AAALAC International

Welcome to Boston!

We are delighted to be back as co-chairs of the 2015 IACUC Conference! This year’s meeting offers a dynamic opportunity for anyone involved in the ethical and regulatory considerations of animal care and use to learn, improve, and make connections that will help them succeed.

Welcome from the Co-Chairs

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Announcements

Breakfast at the IACUC ConferenceFor those interested in grabbing a bite before the meeting starts each day, please visit the breakfast kiosks or Starbucks located in the lobby of the hotel for grab-and-go breakfast options, or Sauciety Restaurant, also located in the lobby, for a sit-down breakfast. Coffee will be served in the Grand Ballroom Foyer each morning before general session. Please note that the breakfast special events on the schedule will have breakfast served and pre-registration is required.

Certificate of Attendance A certificate of attendance for the 2015 IACUC Conference will be provided to attendees upon completion of the online conference evaluation. Please note that this year attendees will be emailed an evaluation at the conclusion of each conference day (March 19 and 20). The certificate of attendance will be included at the end of the March 20 evaluation.

Certificates of attendance for the Essentials of IACUC Administration Pre-Conference program will also be available upon completion of the online course evaluation, which will be emailed to attendees on March 18.

Certificates of attendance for IACUC101TM: The Basics will be available to attendees onsite, upon completion of the session.

Such certificates can be used to obtain continuing education credits from various professional associations. Please note that each association’s guidelines for acceptance of conference credit hours may differ, and you should consult the appropriate association for information as to whether, and how many, credits from PRIM&R conferences may be used.

Conference Blog SquadMeet the 2015 IACUC Conference Blog Squad!

• Kathy Banks, BSc, MSc Continuing Review Coordinator, Animal Ethics, University of British Columbia

• Angela Craig, DVM Lab Animal Veterinarian and IACUC Member, University of Minnesota

These Blog Squad members will be covering sessions, events, and the 2015 IACUC Conference at large for PRIM&R’s blog, online at www.primr.org/blog.

Courtesy Reminder As a courtesy to the speakers and other registrants, please turn off or silence all cell phones and electronic devices during sessions.

Supporter and Exhibitor AreaWe hope you’ll find time to visit our IACUC Conference supporters and exhibitors, located in the Grand Ballroom and Commonwealth Foyers. While there, stop by the PRIM&R booth to learn more about member benefits and to pick up free gifts and resource materials to bring back to your colleagues who weren’t able to attend.

First-Time Attendees Please help us welcome first-time attendees! You’ll know who they are by the rainbow-colored ribbons attached to their name badges.

Session Materials To access session materials using the interactive schedule, visit bit.ly/iacuc15schedule.

1. Locate the specific session on the full schedule by scrolling or using the search field. You can also search by clicking on the Conference Schedule, which allows you to browse by date, title, target audience, track, or keyword.

2. If materials are available for a session, a document icon will appear next to or below the session title.

3. Click on the session title to access the materials. 4. Enter the handout code found on the back of your

name badge (this was also emailed to you before the conference).

Please check the interactive schedule periodically, as additional materials are posted as they are received. Please note that not all sessions have handouts. You may print materials for any and all of the sessions that interest you. After the conference, audio and video recordings for designated presentations will be accessible through the interactive schedule.

Help Us Improve Our goal is to make each IACUC Conference a positive experience for all who attend, but we can’t do it without you. We want to hear your thoughts on what we did well and what we could do better. Please use the notepaper in the back of this guide to capture your thoughts while onsite, and then take a few minutes to complete the daily evaluations, which will be emailed to you at the conclusion of each conference day (March 19 and 20). Thank you in advance for your feedback.

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In Case of Emergency If friends or family need to contact you and cannot reach you directly, they should call the Westin Boston Waterfront security at 617.532.4898. In the event of any emergency, please call 911, and then place a secondary call to the hotel security department for in-house response (4898 on any in house phone or 617.532.4898 from a cell phone). The Westin Boston Waterfront’s security associates are trained and certified to respond to most medical emergencies that may arise at the hotel, and AED devices are located in the fitness center, the reception desk, and the security office.

Internet Café and Wireless Internet Want to check email or review the conference handouts electronically? You’re welcome to use one of the computers in the Internet Café located in the

Commonwealth Foyer or you may connect wirelessly using your own device. To access the wireless internet, select the WestinBostonMeeting or WestinRetail wireless network and enter PRIMR2015 as the password.

If you are using a smartphone or tablet, please connect to the wireless network using the instructions above. Please note that you will have to open your web browser and enter the user name and password before you can use any application requiring the internet. Please log off the wireless internet when you are not using it, and please refrain from downloading large files.

Lost and Found Please call 617.532.3800 to be connected to the Westin Boston Waterfront security for assistance with lost and found items.

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Announcements

Luggage Storage On the morning of your departure, we recommend that you check your luggage at the bell stand of the hotel and return there prior to your departure.

“M” on Badges The letter “M” on your badge designates your status as a member of PRIM&R. If there is no “M” on your badge and you would like to become a member, please visit the Help Desk.

Messages Looking for a colleague? Please post messages to the bulletin board located next to the PRIM&R Help Desk in the Commonwealth Foyer.

Name Badges and Agendas Please wear your name badge at all times. Also note the personalized agenda included with your name badge may not reflect the most recent schedule changes or cancellations, so please double check your schedule against the daily schedules available at Registration.

Networking Ribbons Are you a first-time attendee, IACUC administrator, IACUC chair, IACUC member, researcher, institutional official, or university faculty member? Then don’t forget to pick up these name badge ribbons at Registration. Networking ribbons are designed to enhance community building and to help you connect with colleagues who share similar professional experiences.

Nursing Mothers For those requiring a quiet and private space to pump during our conference, PRIM&R has set aside a room for your convenience. Please visit the Help Desk to obtain access to this room.

Onsite Photography A professional photographer will be onsite to capture images from this event, as part of PRIM&R’s efforts to create an enduring photo archive. We hope you are willing to be a part of it. Photos taken at this year’s conference may be used on our website and/or for other promotional purposes. If you do not wish to have your photograph taken and used by PRIM&R, please alert the photographer. The photographer has been instructed to honor the request of anyone not wishing to be photographed.

PRIM&R’s Green Initiatives We’re doing our best to make the 2015 IACUC Conference another “green” PRIM&R meeting, and we hope you’ll join us in our efforts! PRIM&R’s

environmentally conscious initiatives include: using an electronic evaluation; providing a reusable tote bag; printing this guide using soy-based ink; and using a printer for this guide that runs entirely on wind energy.

The Westin Boston Waterfront is also devoted to maintaining and cultivating green meeting practices, and has received the Green Key Eco Rating from the Hotel Association of America. The hotel’s policies and practices include, but are not limited to: offering guest incentives through their Make a Green Choice program; high-efficiency lighting; water conserving bathroom fixtures and toilets; recycling paper, corrugated cardboard, glass, plastics, and metals; composting of organic wastes; sustainable food service and packaging; and more.

Principles and Expectations for Participation at PRIM&R ConferencesThe objective of PRIM&R’s educational programs and conferences is to provide a safe and respectful environment for attendees to increase their knowledge and understanding of ethical and regulatory requirements, learn best practices, grapple with both late-breaking and longstanding challenges, and confer with peers and experts in the research ethics field in a constructive way.

PRIM&R is committed to being an impartial convener within the research ethics field, which encompasses people with a range of differing opinions. PRIM&R values freedom of expression, constructive and respectful dialogue, and spirited discussion, as they are essential to finding common ground and advancing the goal of responsible, ethical conduct of research with human subjects and animals.

To preserve the objectives and integrity of its educational programming and conferences, PRIM&R will not tolerate the disruption of conference sessions that results in:

• The inability for the learning objectives of sessions to be met

• The inability for dialogue, discussion, debate, learning, and/or networking to take place

• Harassment, badgering, or verbal threats • The use or threat of physical force by any individual

or group of individuals against another • Destruction of property

Aisle microphones will be set up in the keynote and plenary sessions, so please come forward with questions and/ or comments. In the interest of promoting learning for all participants, please keep questions and comments as brief and on-point to the session topic as possible, identify yourself when you ask your question, and be mindful of others who wish to participate in the discussion.

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Special thanks to the Edna H. Tompkins Charitable Trust

for its generous support of this meeting

Registration and the Help Desk Registration and the Help Desk are located in the Commonwealth Foyer, and will be open during the following hours:

• March 17: 10:00 AM-6:00 PM • March 18: 7:00 AM-6:00 PM • March 19: 7:00 AM-6:00 PM• March 20: 7:00 AM-3:00 PM

Please stop by the Help Desk with questions, and a PRIM&R staff member will be happy to assist you.

Religious Observance and Prayer For those requiring a quiet space to pray and/or observe other religious practices during our conference, PRIM&R has set aside the Hale room, on the Mezzanine Level, for your use. This room will remain open to all throughout the conference. Yoga mats will be available in the room.

Sessions To keep the conference running on time, please familiarize yourself with the location of the sessions you plan to attend, so you can arrive promptly at the session’s start time. Maps are included in the back of this guide and are set up as posters at Registration. Additionally, our staff is ready to help with directions or with any questions you might have.

Also, it’s important that you attend the sessions for which you pre-registered, as space is limited. Please refer to the schedule in this guide for more information.

Shipping, Fax, and Photocopy Services Penfield’s Office and Gift Shop, located on the Lobby Level, offers shipping, mailing, faxing, and photocopying services. Penfield’s is open 6:00 AM-7:00 PM each day of the meeting.

Special Meals If you indicated a specific dietary request as part of your registration, please alert a server to your needs before you are seated. Please see a PRIM&R staff member (wearing a staff badge) in the meals rooms or at the Help Desk with questions or concerns.

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Institutional Capacity Building Scholarship ProgramMany small, underfunded institutions of higher education in the United States need—and lack—fully functioning IACUCs. Of these, many institutions support primarily minority populations with educational disparities, such as Historically Black Colleges and Universities, Hispanic-Serving Institutions, and Tribal Colleges and Universities. Others are health institutions serving minority populations with significant health disparities, such as community clinics, regional or area Indian Health Boards, and tribal governments. In addition, many of these institutions are being asked to take on greater roles in research by participating in studies or initiating their own research activities.

To help strengthen these organizations, PRIM&R offers the 2015 IACUC Conference Institutional Capacity Building Scholarship Program, believing that participation in PRIM&R’s IACUC conference offers valuable professional development, education, and networking that will aid in addressing these disparities. A full scholarship includes travel arrangements, hotel

accommodations, and waived registration fees. This year, two institutions are benefiting from this program. Applications and more information for the 2016 IACUC Conference Institutional Capacity Building Scholarship Program will be made available in November 2015.

General Assistance Scholarship ProgramThe General Assistance Scholarship Program assists those members of our community who cannot attend the 2015 IACUC Conference due to financial constraints. Specifically, the program’s goal is to ensure that community and non-scientist IACUC members receive the same educational opportunities as their colleagues so they may further develop their IACUC knowledge.

Names of recipient institutions and individuals are not published to protect privacy, but PRIM&R is pleased to note that four institutions and 17 individuals are benefiting from these opportunities at the 2015 IACUC Conference. Applications for the 2016 IACUC Conference will be accepted beginning in November 2015.

Scholarships

Many thanks to Pfizer, Inc. for supporting this year’s Scholarship Program

The CPIA credential…•StrengthensthequalityofIACUCsbyprovidinganestablishedbodyofrelevantknowledgeandnationalstandardsofpracticeinIACUCadministration

•Validatesanindividual’sprofessionalexperienceandmasteryofthebodyofknowledgedeterminedbynationalexpertstobeessentialtocompetentIACUCadministrativepractices

•DemonstratesthecertifiedIACUCprofessional’shighlevelofdedicationtoIACUCadministrationasaprofession

•Providespotentialcareeradvancementopportunities

CompleteinformationabouttheCPIAprogramcanbefoundonthePRIM&Rwebsiteatwww.primr.org/certification/cpia.

CPIA ExamsExaminationsareconductedduringtwoperiodsinthespringandfall.Thespring2015examregistrationdeadlinehaspassed.ThefallexaminationdeadlineisAugust25,andthetestingperiodisOctober10-24,2015.

CPIA RecertificationParticipationinthe2015 IACUC ConferencequalifiesascontinuingeducationforthepurposeofCPIArecertification,andparticipantscanearnamaximumof16.25credits.Credithoursforthepre-conferenceprogramsvarydependinguponthedurationofthecourse;pleaserefertopage10fordetails.

CPIA at the 2015 IACUC ConferenceIndividualswithquestionsaboutrecertificationorwhoareinterestedinearningtheCPIAcredentialshouldconsiderattendingthefollowingsessions:

• CPIA Networking Continental Breakfast Friday, March 20, 7:00-8:00 AM, Grand Ballroom CD CPIA-certifiedindividualscanconnectwithoneanotheranddiscussrecertificationwithmembersoftheCPIACouncil.Pre-registration required.

• C7: What is the CPIA Credential? Is it for You? If So, How Do You Prepare? Friday, March 20, 10:45 AM-12:00 PM, Grand Ballroom E ThissessionisforindividualsinterestedinearningtheCPIAcredential.

A special thank you to the Council for Certified Professional IACUC Administrators (CCPIA)!

PRIM&RwouldliketothankthecurrentmembersoftheCCPIAfortheirdedicationtotheprogram:

Deb A. Frolicher Chair

Marcy Brown Vice Chair

David G. Cannon Jamie Gothro Molly Greene

William Greer Tracy M. Heenan Alison D. Pohl Shannon Stutler Sally WestlakeJustin A. McNulty

PRIM&R established the CPIA® credential in 2007, and since then, nearly 500 individuals have become certified. This certification was created to improve the quality of animal care and use programs nationwide and promote ethical practices and advanced knowledge of IACUC administration.

Recognition

prim&r’s 2012 advancing etihcal research conference

Conference Information



prim&r’s 2012 advancing etihcal research conferenceprim&r’s 2015 institutional animal care and use committee conference

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Pre-Conference Programs

PRIM&R’s 2015 IACUC Pre-Conference programs will be held on March 17-18. As registration for these programs is now closed, only those attendees who pre-registered are able to participate in these courses.

Boxed lunches will be provided for both sessions on March 18. Please review your program’s agenda, as lunch times differ for each course. Please consult the room assignments below for your program and lunch locations.

At the conclusion of the 2015 IACUC Pre-Conference programs, you will be asked to complete an evaluation. Your feedback is essential to improving the quality and scope of our educational programming, and we would appreciate your completion of this survey.

• Essentials of IACUC Administration attendees will receive the link to the evaluation electronically, and the certificate of attendance will be available at the end of the evaluation.

• IACUC 101TM: “The Basics” attendees will receive their evaluation and certificate of attendance onsite.

Essentials of IACUC Administration March 17, 12:00-5:00 PMMarch 18, 8:00 AM-5:00 PMHarbor Ballroom II(Lunch on March 18 will take place in Harbor Ballroom III)

Faculty: Marcy Brown, BS, MA, CPIA; Deb A. Frolicher, BS, CPIA; Mary Jo Shepherd, DVM, CPIA

Essentials of IACUC Administration has been approved by the CPIA® Council for 12.25 recertification credit hours. This course is also eligible for up to 12.25 continuing education hours and participants will receive a certificate of attendance, which they can then submit to their accrediting body.

IACUC 101TM: “The Basics” March 18, 8:00 AM-5:00 PMGrand Ballroom AB(Lunch will take place in Commonwealth Ballroom ABC)

Faculty: Lynn C. Anderson, DVM, DACLAM; John F. Bradfield, PhD, DVM, DACLAM; J.G. (Jerry) Collins, PhD; Cynthia S. Gillett, DVM, DACLAM, CPIA; Mary Lou James, BA, LATG, CPIA; Monte Matthews, BA, CPIA; Marky Pitts, CPIA; Ernest D. Prentice, PhD; Susan Silk, MS; Tanya Tims, BS, DVM

IACUC 101TM has been approved by the CPIA® Council for 6.5 recertification credit hours. This course has also been approved by the American Association of Veterinary State Boards (AAVSB) Registry of Approved Continuing Education (RACE) program for 6.5 hours of continuing education in jurisdictions that recognize AAVSB RACE approval.

Pre-Conference Programs Networking Reception March 18, 5:00-6:30 PMGrand Ballroom Foyer


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Your Guide to the Tracks

1 Animal Well-Being and the 3Rs

This track reviews issues related to animal well-being, including the 3Rs, pain and distress, social housing, breeding schemes, environmental stress, tumor burden policies, humane endpoints, reuse of animals on teaching protocols, anesthetics and analgesics, and more.

2 Communication and Advocacy

This track provides attendees with an opportunity to engage in an open dialogue on issues of importance to institutional officials, investigators, IACUC chairs, attending veterinarians, IACUC administrators, and unaffiliated/non-scientific members. In addition, this track focuses on strategies for improving internal and external communications, FOIA, dealing with conflicts, managing the inspection process, and more.

3 Hot Topics, Trends, and Special Issues

This track consists of sessions addressing issues that may be novel and/or particularly complex.

4IACUC Administration/Management and Process

This track addresses issues of importance to IACUC administrators, coordinators, and managers, including the roles and responsibilities of IACUC administrators, implementing the Guide, IACUC policies and procedures, IACUC forms, recordkeeping, protocol review and management, IACUC jurisdiction, and more.

5 Not Your Average IACUC

This track reviews the issues that can arise with protocols dealing with large animal models, wildlife, or other non-traditional species, as well as issues of importance to small research organizations.

6 Program Oversight

This track covers issues of importance to overseeing an animal care and use program, including satellite housing, self-imposed regulatory burden, privately owned animals, program review and facility inspection, post-approval monitoring, auditing outsourced activities, managing catastrophes, occupational and environmental health and safety, and more.

7 Protocol Review

This track is designed to help those who work with or on animal care and use programs to effectively read, write, and review protocols. Topics include assisting the principal investigator and research staff, harm/benefit analysis, significant changes, congruency between grants and protocols, and more.

8 Qualifications and Training

This track helps attendees develop effective educational programs for the assorted stakeholders involved in the IACUC process. Faculty members in each session plan to discuss the various resources available for education and training.

9 A Conversation With…This track provides attendees with an opportunity to hear from, and ask questions of, representatives from various oversight agencies and AAALAC International.

TRACKS DESCRIPTORS

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Your Guide to the Conference Schedule

The 2015 IACUC Conference features a wide variety of breakout sessions on a multitude of topics. To make the breakout sessions easy to navigate, we have organized them into nine thematic categories called “tracks.” Within each track, there are three types of breakout sessions: workshops (interactive), didactic sessions (presentation-based), and double sessions (hybrid workshops/didactic sessions that are twice as long as regular breakout sessions).

Since there are so many choices, we advise you to use the descriptors to identify the breakout sessions that are most relevant to your needs and interests. As you consult these descriptions, please also note the following:

1. Double sessions are held over lunch and include a boxed meal. For double sessions on March 20, attendees should pick up their lunch in Grand Ballroom CD before arriving at the session room. Please note that pre-registration was required for these sessions to help ensure adequate seating. If you did not pre-register, but would like to attend, please go to the session room and wait until the session starts to see if seats are available.

2. The tracks are not meant to be exclusionary; everyone is welcome to attend any session. For example, feel free to attend a session in the “IACUC Administration/Management and Process” track even if you are not an IACUC administrator.

3. Sessions marked basic provide an introduction to the topic being discussed for those who have little or no prior knowledge of it. The focus is on introducing, explaining, and illustrating basic concepts, principles, regulations, policies, or best practices relevant to the topic.

4. Sessions marked advanced assume mastery of central ethical concepts and principles, of the regulations, and of the processes of applying them to the day-to-day work of protocol review or other research oversight activities. These sessions provide attendees with in-depth knowledge of an area and a robust set of skills required for addressing difficult

problems and navigating “grey areas” in that area, improving their animal care and use programs, shaping their institutional cultures, or advancing their careers. Sessions will often make heavy use of active learning techniques, such as case studies. Attendees are expected to have sufficient experience and understanding of the topic in order to actively contribute to the discussion and the solution of difficult problems. These sessions will not review basic concepts.

5. Sessions that do not have a learning level listed are intended for all audiences.

Icon KeyIndicates a didactic session (presentation-based)

Indicates a workshop (interactive)

Indicates a double session (hybrid workshops/didactic sessions; see note above about double sessions)

Indicates session will be recorded for the conference proceedings

Pre-registration was required. Please visit the Help Desk to inquire about space availability.

Indicates a session chosen from our Call for Session Proposals


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Thursday, March 19

7:00 AM Commonwealth FoyerRegistration OpensBreakfast on your own. Please visit the kiosks or Starbucks in the hotel lobby for grab-and-go options, or Sauciety, also in the hotel lobby, for a sit-down breakfast. Coffee will be available in the Grand Ballroom Foyer before general session.

7:00-8:00 AM Grand Ballroom CD

Continental Breakfast to Welcome First-Time Attendees Is this your first time attending the IACUC Conference? If so, please join us at this special breakfast to welcome first-time attendees. During this event, you’ll have an opportunity to meet and network with colleagues, as well as hear answers to the most frequently asked questions about the conference from the PRIM&R staff.

8:00-8:15 AM Grand Ballroom AB

Welcome from the 2015 IACUC Conference Co-ChairsF. Claire Hankenson and Christian E. Newcomer


Keynote Address: Field and Laboratory Animal Research in Emerging ZoonosesDarin S. Carroll, PhD, Acting Branch Chief, Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention


Panel I: Structuring Your IACUC for Efficiency and to Facilitate ResearchModerator: Melinda B. HollanderPanelists: Valerie K. Bergdall, Sally E. Light, Leo E. OtterbeinIn March 2014, the National Science Board (NSB) issued a report titled Reducing Investigators’ Administrative Workload for Federally Funded Research. Included in this report was the notion that compliance with the proliferating requirements of IACUCs (and review boards in general) poses a very significant regulatory burden to researchers. Regulatory requirements define the essential activities and intended outcomes of the IACUC oversight process, but offer no guidance on the style, intensity, or efficiency of the IACUC-researcher interactions necessary to achieve satisfactory regulatory outcomes. Many IACUCs have encountered occasional unsatisfactory outcomes in approved research animal studies, either due to inadequate protocol review/approval or research deviations from the approved protocol, and institutions

seem predisposed to ramp up requirements for protocol review to compensate for these failures. The NSB report cites internal policies that exceed regulations as a large problem, noting that management of “risk intolerance” is key to “reducing administrative burden.” Increasingly, institutions and their IACUCs are striving for reduced administrative burden with no decrement in performance in regulatory compliance. This high expectation requires IACUCs or more typically the IACUC administrators, to devise new approaches to create highly efficient programs meeting both objectives. Through the lens of a program director, IACUC administrator, and chair who also conducts research, this panel will provide insight on self-imposed regulatory burden, ways to reduce the burden on researchers, strategies for improving IACUC efficiency, and how IACUC administrators can clarify, narrow, and navigate the zone of arbitration between regulatory and research expectations.

10:15-10:45 AM Grand Ballroom Foyer Break

Join us for coffee.

10:45-12:00 PM Didactic Sessions and Workshops Series A

A1 Harbor Ballroom III

How to Discuss and Reach Consensus as an IACUC on Studies Involving Unalleviated Pain and Distress (Animal Well-Being and the 3Rs Track) Tim Allen, Barbara A. Garibaldi During this session, faculty and attendees will:• Review published guidance from the NIH, the Guide, and USDA to better categorize protocols

• Discuss the legal and ethical obligations for minimizing pain and distress in animals

• Use specific examples to discuss individual and collective responsibilities, the development and validation of humane intervention points and endpoints, and the implementation and assessment of specific measures for minimizing pain and distress

• Explore the use of observation to optimize animal welfare

• Outline strategies for evaluating the concerns that pain management medications will be incompatible with proposed animal experiments

• Examine the role of non-pharmacological palliative care in animal models experiencing pain and distress

Thursday, March 19

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A2 Commonwealth Ballroom A

Social Housing for Species Other than Mice and Monkeys (Animal Well-Being and the 3Rs Track) David Lee-Parritz, Jennifer Lofgren The Guide now recommends that social housing be the default for most research species. Yet, intra-species aggression can present challenges to meeting this recommendation. During this session, faculty and attendees will:• Share common problems faced in meeting social housing requirements, particularly for rabbits and pigs

• Discuss possible solutions to fulfill the needs of social animals maintained at biomedical research sites

• Explore specific cases related to social housing at individual institutions

A3 Alcott

Open Forum for Investigators (Communication and Advocacy Track) Dara Kraitchman, Kenneth M. Rosen This interactive session will provide a forum for principal investigators to discuss the issues they face in carrying out their duties in conducting research. During this session, faculty and attendees will:• Discuss the challenges faced by investigators at various institutions and the support needed to carry out those responsibilities

• Review the methods used by principal investigators to ensure compliance in protocols and to ensure the humane care and use of animals in their studies

• Share strategies on fostering a strong IACUC-principal investigator partnership, including knowing in which situations IACUC intervention may be needed, and exploring how positive resolution can be achieved through relationship-building

A4 Faneuil

The Fundamentals of FOIA(Hot Topics, Trends, and Special Issues Track) B. Taylor Bennett, Elizabeth Goldentyer, Margaret D. Snyder, Axel V. Wolff During this session, faculty will:• Review the requirements of FOIA and state open records acts

• Review how the USDA and NIH handle FOIA requests

• Address what types of information should be kept and why, and how to create a retention policy

• Outline what to do if records are requested

A5 Burroughs

Top Deficiencies from the Perspectives of AAALAC, OLAW, and USDA (Hot Topics, Trends, and Special Issues Track) John F. Bradfield, Carol Clarke, Brent C. MorseDuring this interactive session, attendees and representatives from federal agencies and the accrediting body will:• Discuss the most common problems encountered during inspections and site visits

• Identify the common deficiencies self-reported by institutions

A6 Harbor Ballroom II

IACUC Boot Camp (IACUC Administration/Management and Process Track) Mary Lou James, Monte Matthews, Marky E. Pitts, Michael Smith (USDA resource person)This session is for those individuals new to the field, and will provide a comprehensive overview of oversight process, IACUC functions, regulations, frequently used acronyms, the Guide, protocol review, and committee make-up. During this session, faculty and attendees will:• Review frequently used acronyms• Examine specific USDA and OLAW regulations and AAALAC requirements

• Outline IACUC membership requirements• Discuss IACUC responsibilities and charges• Address the protocol review process (e.g., full committee review and designated member review, protocol form components, amendments: minor vs. significant modifications)

• Review other required institutional program components (e.g., occupational health and safety programs, training programs, and emergency/disaster plans)

Please note this is a double session and will go until 1:30 PM. Boxed lunches will be available at the session room.

A7 Commonwealth Ballroom C

Reporting Departures in the Semiannual Report to the Institutional Official: Identifying and Tracking Departures Effectively

(IACUC Administration/ Management and Process Track) Patricia A. Brown, Melinda B. Hollander, Elizabeth Meek During this session, faculty will:• Define “departure” based on the PHS Policy and the AWA regulations

• Review OLAW’s and USDA’s reporting requirements for departures

• Provide case studies involving departures• Discuss ways to track and document departures

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A8 Hancock

Managing Nontraditional Species When They Come Into the Laboratory (Not Your Average IACUC Track) Joanne Morris, Robert S. Sikes During this session, faculty and attendees will:• Address IACUC oversight challenges in managing nontraditional species, including reviewing protocols, performing inspections, and ensuring proper care

• Discuss how the IACUC, facility, and principal investigator can address the unique housing and husbandry of nontraditional species, including the use of experts and taxon-specific guidelines

• Review the occupational health concerns related to nontraditional species

A9 Otis

What IACUCs Need to Know About Laboratory Aquatics Oversight (Not Your Average IACUC Track) Brian Frederick, Christian Lawrence, Stacy Pritt This session will focus on what IACUCs need to do to provide competent oversight of laboratory aquatic animal programs, including frogs, zebrafish, etc. From initial education of IACUC members, implementation or affirmation of appropriate policies, and facilitation of the research, this session will prepare IACUCs for effective oversight of the care and use of aquatic species. During this session, faculty and attendees will: • Review what training should be provided to IACUC members and staff to be able to effectively oversee research with laboratory aquatic animals

• Discuss what IACUC policies need to be revised or created when adding laboratory aquatic animals to a research program

• Address the unique occupational health concerns that aquatic animals pose

• Share strategies on principal investigator care of these animals, including housing and husbandry

A10 Adams

Satellite Housing Areas: How to Ensure IACUC and Attending Veterinarian (AV) Oversight of Health and Well-Being (Program Oversight Track) Donna Matthews Jarrell, Christina NascimentoSatellite housing areas (i.e., housing areas for animals not maintained within a centralized facility) are often necessary due to equipment needs, behavioral assays, sensitive tissue harvests, and space restrictions. However, these areas can become difficult for the IACUC and the AV to manage, may not provide the best environmental conditions for maintaining

animals, may be inappropriately justified as a convenience for investigators, and may serve as a potential liability for institutional commitments to animal welfare. During this session, faculty and attendees will:• Discuss how programs can evaluate criteria for appropriate satellite housing justification

• Explore how to develop and review satellite housing areas that are compatible with the need for animal comfort, health and welfare, veterinary care, biosecurity, and occupational health and safety measures

• Review compliant centralized reporting mechanisms for animals maintained in approved satellite housing areas

A11 Harbor Ballroom I

Self-Imposed Regulatory Burden: When We Do Too Much (Program Oversight Track) Valerie K. Bergdall, Deb A. Frolicher, Christian E. Newcomer, Steven M. Niemi, Joseph D. Thulin This session will focus on the choices institutions make to achieve regulatory compliance in their animal care and use programs, particularly those choices that produce burdens in excess of explicit regulatory requirements. The negative impact of regulatory burden in animal-based research has long been a concern for researchers, and has been the topic of a recent federal report as well as recent literature. During this session, faculty and attendees will:• Review the root causes and effects of excessive self-imposed regulatory burden, as well as the common ways in which institutions voluntarily adopt burden in excess of regulatory requirements

• Outline the most common organizational structures used to oversee animal care and use programs, including the costs and benefits associated with these structures

• Explore ways to avoid and mitigate unnecessary self-imposed burden without sacrificing program quality

• Share strategies for how to critically assess the performance of oversight at your institution

A12 Douglass

How to Assist Research Staff and Principal Investigators in Writing a Protocol (Protocol Review Track) Chieko Azuma, Nancy Figler Marks, Jennifer A. Perkins This session is geared toward IACUC staff that assist research staff and principal investigators in writing protocols. During this session, faculty will:• Review standard language sections• Outline issues related to animal number

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justification and calculating animal numbers, including breeding numbers

• Provide insight on when to include veterinary pre-review for all protocols

• Address how to assess and advise investigators on how to write sections that request exemptions from standard policies (e.g., enrichment, space, social housing, cage sanitation frequency, etc.)

• Discuss the use of pre-populated protocol forms for common procedures

A13 Stone

Assessing and Ensuring Qualifications, Competence, and Proficiency of Research Personnel (Qualifications and Training Track) Szczepan Baran, Jon D. Reuter, William Singleton Technical competence and proficiency in the care and use of research animals is the ultimate goal for assuring compliance, regulatory mandates, and improving animal welfare. During this session, faculty and attendees will:• Review the methods that work best in various settings for assessing qualifications, competence, and proficiency

• Discuss staffing, training metrics, and documentation that must be factored into the development of an assessment method that best fits an institution

• Assess best methods for assembling a training team

A14 Carlton

Training Your Police, Security, and Facility Personnel on Biomedical Research Security Concerns (Qualifications and Training Track) Charles P. “Bud” Burnett, Jr., Jori K. Leszczynski, Patricia A. Preisig This interactive session will discuss security issues and provide information on how to train your police, security, and facility personnel on biomedical research security concerns. The session’s objective and take-away tool is the development of a PowerPoint presentation that will be created during the session and is based on the group’s discussion of the issues for the attendee’s presentation to those expected to protect animal-based resources within their institution. Each attendee will be emailed the final presentation in a format that allows them to incorporate institutional logos, formatting, etc. During this session, faculty and attendees will:• Discuss the background of and pertinent points of biomedical research

• Review and determine the information derived from the group’s discussion as points

relevant to teaching their institution’s security personnel and others (e.g., new hires, IACUC members, etc.)

• Generate a list of suggestions on how to build a strong institution-wide security program

• Design a PowerPoint presentation that each member will receive for optional edit and use at their institution

A15 Commonwealth Ballroom B

Current Animal Research Topics: Doing Right by the Animals to Serve Veterans (A Conversation With… Track) Michael T. Fallon, Susan Harper, Alice Huang, Joan T. Richerson This interactive workshop session is designed to provide an opportunity for participants to engage VA representatives on current topics relevant to VA and non-VA animal care and use programs.The VA research and development program supports research that is needed for a fuller understanding and better treatment of the healthcare needs of veterans, which is also invaluable for addressing healthcare needs of people in general. VA requires adherence to the highest ethical and legal standards, which includes compliance with the regulatory requirements of the USDA and the PHS, and with AAALAC’s Rules of Accreditation, as well as a few additional VA-specific requirements, to ensure appropriate care and use of the animals. In this session, faculty and attendees will:• Hear brief updates on the VA animal research program

• Discuss the application of recent guidances from OLAW (on significant modifications of approved protocols) and from the USDA (on annual continuing reviews)

• Work through some complex scenarios involving one or more Guide deviations and departures.

12:15-1:30 PM Galleria HallCommon Ground Networking Lunch Time to connect… over lunch! Meet peers for conversation and networking. The tables will be divided by institution type: University/College (Medical), University/College (Non-Medical), Hospital/Medical Center, Government Agency, Pharma/Biotech Company, and Small Research Programs. We will also have tables available for those wishing to “just lunch.” All are welcome!

1:45-2:30 PM Grand Ballroom AB

Keynote Address: Modeling the Origins and Mechanisms of Cystic Fibrosis David K. Meyerholz, DVM, PhD, DACVP, DACVM, Director, Division of Comparative Pathology; Associate Professor, Department of Pathology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa


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Panel II: Studies of Animals When They Are the Targeted BeneficiariesModerator: Robert S. Sikes Panelist: Darin S. Carroll, Jeremy T.H. Coleman, David K. Skelly This panel will address the use of animals in areas beyond biomedical research focused on human health, as any focus on issues where animals are the primary beneficiary inevitably affects humans. This may occur through spillover of diseases (e.g., Ebola, Marburg, etc.), through unintended alteration of animal populations or communities (e.g., Chytrid link to Xenopus harvested and used for biomedical research and its effect on wild populations, etc.), or through changing our use of land to protect animal populations (e.g., closing of caves and altering logging practices because of white nose syndrome). Through a series of three talks, this panel will evaluate ethics from a broad perspective and how impacts on animal populations can also affect humans.

3:45-4:00 PM Grand Ballroom FoyerBreak Join us for coffee and cold drinks.

4:00-5:15 PM Didactic Sessions and Workshops Series B

B1 Hancock

Consequences of Environmental Stress (Animal Well-Being and the 3Rs Track)Kathleen R. Pritchett-Corning, TBD During this session, faculty will:• Discuss the implications of bedding, caging, nesting materials, light, noise, magnetic fields, and male vs. female experimenters/husbandry staff on mouse well-being and research outcomes

• Review information on social housing for mice• Examine whether the Guide recommendations regarding social housing for mice (e.g., mouse room temperature) may exacerbate the environmental stress problem

B2 Commonwealth Ballroom C

Rightsizing the Tumors to the Science Tumor Burden Policies (Animal Well-Being and the 3Rs Track) F. Claire Hankenson, Scott E. Perkins During this session, faculty will: • Review types of tumors and how tumor type and scientific objectives impact guidelines and handling

• Address imaging for metastatic tumors • Outline issues related to the establishment of humane endpoints and facilitating timely intervention

• Describe resources and strategies available to IACUCs working to create and implement tumor burden policies

B3 Burroughs

The IACUC’s Role in Maintaining Institutional Credibility (Communication and Advocacy Track) Rob W. Anderson, Allyson J. Bennett, Patricia A. Brown, Paula S. Gladue (USDA resource person) In an era of 24-hour news media, an institution may only have seconds to decide how to present findings to preserve or rebuild its reputation around sensitive topics. Knowing the steps to take, and practicing them beforehand, can give IACUC members the confidence to participate in the communication process at critical touch points during an investigation. During this session, faculty and attendees will:• Use real-life scenarios to examine what happens when information is leaked, distorted, or both, and how to mitigate these situations

• Analyze the communication situations that can sabotage trust in the institutional oversight process

• Explore how perceptions can be powerful influencers in the IACUC investigation process

• Share information that advances understanding of how oversight agencies respond to reported concerns or complaints

• Discuss the possible consequences and/or protections for both individuals and institutions if reports about animal welfare concerns become public

B4 Otis

Open Forum for IACUC Chairs(Communication and Advocacy Track)George F. Babcock, Tammy Dellovade This interactive session will provide a forum for IACUC chairs to discuss the issues they face in carrying out their duties, including their role as leaders in the process of certifying the institution’s compliance with regulations, polices, and guidelines. During this session, faculty and attendees will:• Discuss the roles and responsibilities of IACUC chairs at various institutions and the support needed to carry out those responsibilities

• Examine the core responsibilities of the institutional official from the USDA and PHS perspectives, and delineate the respective responsibilities of the institutional official, the IACUC, and the attending veterinarian

• Review the methods used by the IACUC to deliver quality service, liaise with investigators to resolve problems, promote IACUC programs, and advocate for the development of animal research resources

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B5 Stone

Managing the USDA Inspection Process(Communication and Advocacy Track)B. Taylor Bennett, Robert M. Gibbens This interactive session will review the components of a program for effectively managing the USDA inspection process, as well as provide insight into assuring compliance in frequently cited areas. During this session, faculty and attendees will:• Discuss how to effectively manage the inspection process

• Review recent changes to the inspection process

• Identify the most frequent findings during inspections, and how to assure compliance within the relevant sections of the regulations and standards

• Outline how to handle the appeals process

B6 Lewis

Retiring Research Animals: What You Need to Know (Hot Topics, Trends, and Special Issues Track) Terry L. Blasdel, Tina Grove, Jon D. ReuterDuring this session, faculty will:• Discuss processes for selecting a sanctuary• Outline the financial issues that can occur with adoption of animals

• Address non-disclosure (i.e., how long are the animals the responsibility of the institution, and what happens when a sanctuary or rescue organization goes out of business?)

• Review the steps an institution must consider in preparing animals for adoption

B7 Carlton

A Conversation About Diversity: Why it Matters (Hot Topics, Trends, and Special Issues Track) Eric Allen, Donna Matthews Jarrell, Natalie L. Mays Diversity is one of PRIM&R’s core values. This session will discuss ways to promote regulatory affairs/regulatory compliance as a career option for underrepresented minorities, and to encourage more diversity within the field and within the PRIM&R membership. During this session, faculty and attendees will:• Explore ways to promote science-based careers for underrepresented minorities

• Discuss mentorship of high school and college/graduate school students

• Share recommendations for how to promote animal care and use program careers to a wider audience

• Examine why increased attention to diversity issues within the field is important, including the value of increased sensitivity on the part of compliance personnel who work with or communicate with researchers from multiple nationalities/ethnicities

B8 Douglass

IACUC Administration for New Administrators/Coordinators(IACUC Administration/Management and Process Track) Marcy Brown, Rachel A. Murray, Felicia PonceDuring this session, faculty will review the basics of IACUC administration, including:• The role of the IACUC administrator as customer service agent

• Protocol management and routing • Post-approval monitoring• IACUC/investigator interactions• Fostering a culture of compliance• Dealing with challenging customers and situations

B9 Harbor Ballroom II

How to Conduct Investigations (IACUC Administration/Management and Process Track) Emily Hearne, Elizabeth Meek, Mary Jo Shepherd, Axel V. WolffDuring this session, faculty and attendees will:• Review requirements for addressing animal welfare concerns and noncompliance

• Explore how to assemble an appropriate investigation team/subcommittee

• Share processes and best practices for conducting investigations

• Discuss optimal follow-up and plans for correction and prevention

• Review how to handle situations involving whistleblowers, including how to process and how to respond

B10 Commonwealth Ballroom B

Toolbox for Protocols Using Wild Species (Not Your Average IACUC Track) John A. Bryan, II, Robert S. Sikes During this session, faculty and attendees will:• Discuss ways to fit wildlife research into frameworks designed for domesticated species

• Examine specific protocol needs when the research involves wild species

• Review the often difficult circumstances IACUCs face when evaluating distress and mortality with wild animals, logistical details of anesthesia, analgesia, and euthanasia, safety of research personnel, and periodic evaluation and oversight responsibilities

• Share resources for IACUCs and principal investigators for evaluating and reviewing wildlife protocols

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B11 Harbor Ballroom I

Inter-Institutional Collaborations and Memoranda of Understanding (MOUs): What Are We Responsible For? (Program Oversight Track) Justin A. McNulty, Eileen M. Morgan, Sabune Joane Winkler During this session, faculty will:• Define inter-institutional collaborations and review the regulatory requirements that require attention

• Outline the primary components of a MOU• Review how to ensure animal welfare and appropriate oversight when two very different institutional cultures collide

• Provide strategies for identifying collaborations, and discuss when collaboration necessitates a MOU (e.g., for PHS studies when custom antibodies are being made commercially, when institutions subcontract a portion of a project, and/or when a principal investigator oversees a project outside the home institution)

• Address who initiates the MOU (e.g., the grantee, the subcontractor, or both)

• Share practical examples and templates of MOUs, as well as experiences and ideas about managing collaborations across institutions

B12 Adams

Issues Confronting Institutions and IACUCs Using and Conducting Clinical Trials in Privately Owned Animals (Program Oversight Track)Philippe Baneux, David Lee-Parritz, Sally E. LightThe need to conduct clinical trials in the veterinary patient population for the advancement of veterinary clinical care, as well as the occasional use of privately owned animals in veterinary educational exercises, can pose challenges for the institutions and IACUCs supporting these activities. Once largely in the domain of the veterinary school environment, studies involving veterinary patients in clinical trials are expanding into other institutional environments when investigators seek a comparative medical approach to the development of new therapies. During this session, faculty and attendees will:• Discuss the regulatory, legal, and ethical dimensions of institutional oversight in these studies

• Explore common problems encountered in the review and approval of studies in privately owned animals

• Review useful provisions for veterinary patient protection and institutional protection in these situations

B13 Commonwealth Ballroom A

Program Review and Facility Inspections(Program Oversight Track) Lara A. Helwig, Tracy M. Heenan, Michael Smith, Venita B. Thornton (NIH OLAW resource person) Semiannual program reviews and facility inspections optimally function to aid in developing a sound animal care and use program. However, changes involving the institutional official, IACUC membership, IACUC staffing, organizational resources and infrastructure, and the organization’s scientific mission can frequently precipitate perturbations or perplexing new challenges leading to suboptimal institutional oversight. During this session, faculty and attendees will:• Review the basic precepts of facility inspections and programmatic review

• Identify common and uncommon problem areas

• Explore preemptive or restorative approaches to combat deterioration in oversight

• Address the IACUC administrator’s role in preparing the semiannual report

• Discuss the ins and outs of a semiannual program review, including what is required, who should be involved, and when these reviews must be performed

• Examine examples of reviews performed at various institutions and the common citations issued

B14 Harbor Ballroom III

How to Be Effective at Reading and Reviewing a Protocol(Protocol Review Track) David G. Cannon, Mégan Losh, Angela J. PhillipsReviewing and reading protocols are essential tasks for all IACUC members. Being able to effectively read and assess a protocol to ensure that all regulations, policies, and guidelines are met requires experience. During this session, faculty will:• Outline how to effectively read and review a protocol by examining actual protocols

• Review how to find the balance between conducting a comprehensive pre-review by IACUC staff and crossing over the line of conducting an IACUC protocol review including scientific review

• Provide guidance on how to communicate findings from the protocol review process back to principal investigators in order to receive the answers to the questions that you are really asking

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B15 Alcott

Poster Presentation: Tools for Enhancing Surgical Success (TESS) (Qualifications and Training Track) Colleen Bennett, Barbara A. Garibaldi, David J. LyonsPatient (human or animal) safety and surgical success are the desired outcomes in any operating room (OR). Adequate training and technical excellence alone does not guarantee a positive outcome. Instead, errors that contribute to unexpected complications and poor outcomes may stem from breakdowns in communication, leadership, and teamwork. The reasons for these breakdowns are varied and may include new/transient team membership, uncertain roles and responsibilities, language barriers, social/professional hierarchies, cultural differences, varied team and individual limitations, etc. During this session, one institution will share their experience creating a team-based communication program titled TESS, to help address these issues. During this session, faculty will:• Describe how, in the course of resolving adverse events, the institution surmised that some of the poor outcomes reported may have been due to inadequate pre-planning, lack of communication between surgeon and surgical support staff, and poor situational awareness

• Outline how the institution used practices in the human OR to create the TESS program

• Illustrate how TESS engages the entire surgical team in a process of constant improvement by (a) looking for emerging concerns and potential errors before, during, and after the surgery; (b) asking questions, making suggestions, and voicing concerns; and (c) respecting each team members’ expertise, opinions, and concerns

• Discuss how to implement the TESS program• Demonstrate how TESS has been working at this institution

B16 Griffin

Training and Information for Students Working with Animals in Coursework Activities (Qualifications and Training Track) Melinda B. Hollander, Sarah M. Newman Many programs, particularly those offering agricultural and wildlife courses, involve students working directly with animals. This session will describe ways to ensure students in such courses receive appropriate training and information regarding hazards and concerns related to working with animals. The session will also cover ways to ensure health screening and appropriate participation in the occupational health program. During this

session, faculty will :• Provide strategies to identify students enrolled in these courses

• Discuss ways to document training and receipt of information regarding health concerns

• Outline ways to ensure students are well informed of next steps should health concerns arise

• Describe how to ensure students are knowledgeable about species-specific and project-specific dangers and risks

B17 Faneuil

Time to Connect: A Conversation With the NIH OLAW and USDA/APHIS (A Conversation With… Track) Doreen H. Bartlett, Elizabeth Goldentyer, Brent C. Morse, Susan Silk, Tanya Tims Join us for this special session where attendees can speak with and ask questions of representatives from the NIH OLAW and USDA, APHIS. The NIH OLAW provides guidance and interpretation of the PHS Policy on Humane Care and Use of Laboratory Animals, supports educational programs, and monitors compliance with the PHS Policy by assured institutions and PHS funding components to ensure the humane care and use of animals in PHS-supported research, testing, and training. And, for more than 40 years, Congress has entrusted APHIS with the stewardship of animals covered under the Animal Welfare and Horse Protection Acts. APHIS continues to uphold that trust, giving protection to millions of animals nationwide, and provides leadership for determining standards of humane care and treatment of animals, implements those standards, and achieves compliance through inspection, education, cooperative efforts, and enforcement. This session will provide an opportunity for attendees to:• Ask questions of representatives of the NIH OLAW and USDA, APHIS

• Participate in an open discussion about issues relevant to NIH OLAW and USDA, APHIS stakeholders

5:15-6:30 PM Grand Ballroom AB & Grand Ballroom Foyer2015 IACUC Conference Welcome ReceptionJoin us to celebrate the opening of the 2015 IACUC Conference. During this time, you’ll be able to meet our conference Supporters and Exhibitors, view the Poster Presentations, and receive a complimentary mini-massage. Light refreshments will be served.


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7:00 AM Commonwealth FoyerRegistration Opens Breakfast on your own. Please visit the kiosks or Starbucks in the hotel lobby for grab-and-go options, or Sauciety, also in the hotel lobby, for a sit-down breakfast. Coffee will be available in the Grand Ballroom Foyer before general session.

7:00-8:00 AM Grand Ballroom CD

CPIA® Networking Continental BreakfastDo you hold the CPIA credential and have an interest in connecting with other CPIAs? If so, please join the CPIA Council and PRIM&R staff at this special continental breakfast! We’ll be discussing recertification and answering any of your other questions. If you do not currently hold the CPIA credential, but are interested in taking the exam or learning more about the program, we invite you to attend workshop C7: What Is the CPIA Credential? Is it for You and, If So, How Do You Prepare? on March 20 from 10:45 AM to 12:00 PM.


Welcome from the 2015 IACUC Conference Co-Chairs F. Claire Hankenson and Christian E. Newcomer


Henry Spira Memorial Lecture: Primate Social Intelligence Frans B. M. de Waal, PhD, Charles Howard Candler Professor of Primate Behavior, Psychology Department, Emory University; Director, Living Links Center, Yerkes National Primate Center


Panel III: Fallout from FOIA Moderator: B. Taylor Bennett Panelists: Jori K. Leszczynski, David J. LyonsInformation obtained under FOIA and state open records acts can be used to target institutions, individual research projects, and investigators; call for an increase in enforcement; and initiate legal action. Recently, animal rights groups have requested information on institutions’ assurance documents and self-reports, and this information has been used to issue press releases to ask that the USDA do return visit inspections, and to target institutions for a variety of purposes. As such, this has led to a discussion on the resistance to reporting because of the fear of fallout from FOIA, and on what, how, and how much to report to OLAW and USDA. During this session, the current trends for requesting information, how

this information is being used, and the impact that the release of information can have on institutions and those who must respond on behalf of the institution will be reviewed, as well as how the field can deal with this situation.

10:15-10:45 AM Grand Ballroom FoyerBreak Join us for coffee.

10:45-12:00 PM Didactic Sessions and Workshops Series C

C1 Commonwealth Ballroom C

The 3Rs at Work: Case Studies (Animal Well-Being and the 3Rs Track) Marc T. Avey, Natalie A. Bratcher, Letty V. Medina, Gina R. Prochilo-Cawston, Mary Ann Vasbinder This session will present an overview of case studies and other tools that promote the 3Rs in research. During this session, faculty and attendees will:• Provide examples of how the 3Rs can be promoted within an institution in a variety of ways including by the IACUC, veterinary staff, research staff, cultural changes, and creation of an Alternatives Committees

• Address project planning, refinements of animal care practices, and new technologies that advance the 3Rs

• Present case studies of science-led approaches to implementing the 3Rs (e.g., analgesia in tumor mice, assessment of CO2 euthanasia, zebrafish assays, and liver slice technology)

• Review the importance of experimental design and systematic review of animal models for 3Rs impact including examples of sample size estimation

• Outline how to incorporate ethical review, including moral considerability, into the protocol review process within the framework of the 3Rs

• Discuss continuing education and how to communicate to research investigators the latest advances in the 3Rs (3Rs award, 3Rs symposia, 3Rs goals)

C2 Carlton

Reuse of Animals on Teaching Protocols(Animal Well-Being and the 3Rs Track) Valerie K. Bergdall, James D. Macy, Jr. During this session, faculty will: • Review the regulatory perspective in the United States and globally

• Outline the ethical, educational, and clinical issues pertaining to animals used in teaching protocols in agricultural schools, veterinarian schools, and in pediatrics

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• Provide guidance on the role of patient protection measures in the provision of a quality educational/training experience

• Share how to minimize and manage pain and distress

• Discuss how to develop policies and procedures on reusing animals in teaching protocols

C3 Faneuil

Managing or Avoiding Conflicts Within the Animal Care and Use Program(Communication and Advocacy Track) Marcy Brown, Sally E. Light, Steven M. NiemiMany of the day-to-day issues that arise within an institution’s animal care and use program can be managed with effective communication where all parties have common goals and objectives. During this session, faculty and attendees will:• Outline the process for developing common goals and objectives

• Discuss methods for effective communication• Share tips and tricks to defuse heated situations so constructive progress can be made

• Review how to accept input from various entities within the animal care and use program

C4 Hancock

Open Forum for Unaffiliated/ Non-Scientific Members (Communication and Advocacy Track) Mark S. Christensen, Colleen A. Cody This interactive session will provide a forum for unaffiliated/non-scientific members of IACUCs to discuss issues that arise when carrying out their duties with respect to overseeing animal care and use programs. During this session, faculty and attendees will:• Review the roles and responsibilities of unaffiliated/non-scientific members

• Discuss issues submitted in advance by unaffiliated/non-scientific members

• Explore any other issues raised by attendees during the session

C5 Douglass

Panel II Follow-Up: Fallout from FOIA (Hot Topics, Trends, and Special Issues Track) B. Taylor Bennett, Elizabeth Goldentyer, Jori K. Leszczynski, David J. Lyons, Margaret D. Snyder, Axel V. Wolff During this session, faculty and attendees will:• Continue discussion from Panel II and answer any remaining questions

• Discuss what not reporting does for the larger animal research program

C6 Harbor Ballroom III

Where the Rubber Meets the Road! Challenging Scenarios and Complex Issues in IACUC Administration(IACUC Administration/Management and Process Track) Patricia A. Brown, Robert M. Gibbens, Valerie Parkison, Mary Jo Shepherd This interactive session will provide faculty and attendees an opportunity to:• Work through simulated, problematic scenarios in IACUC administration

• Explore possibilities for resolution without conflict

• Discuss resolving conflict while maintaining compliance

• Address specific scenarios attendees have faced and wish to explore with the group

C7 Grand Ballroom E

What Is the CPIA® Credential? Is it for You? If So, How Do You Prepare?(IACUC Administration/Management and Process Track) Deb A. Frolicher, Rebecca Saez In this interactive session, a member of the CPIA Council, a recently certified individual, and attendees will:• Review the development and status of the credentialing program

• Discuss examination preparation tactics based on first-hand experience

• Answer attendee questions about the CPIA credential and how to prepare for the exam

C8 Adams

IACUC Deliberations Using Wildlife Scenarios(Not Your Average IACUC Track) John A. Bryan, II, Robert S. Sikes This session will present challenging scenarios from the wildlife arena as learning tools for IACUCs and principal investigators. During this session, faculty and attendees will:• Explore situations where specific guidance often is not available either because the situations are new or unique or because relevant information does not exist for the species under study

• Discuss practical strategies for handling similar problems in very different wild species

C9 Otis

IACUC Challenges for Small Organizations(Not Your Average IACUC Track) Michelle Aparicio, Carol Clarke, Jamie Gothro, Eileen M. Morgan In this interactive session, faculty and attendees will focus on creative solutions for

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challenges inherent to small organizations. During this session, faculty and attendees will:• Share strategies for how to create an IACUC from scratch

• Learn how to maintain a small IACUC where members must wear multiple hats

• Discuss how to review protocols (including teaching protocols), perform program reviews, and conduct inspections in spite of limited scientific expertise, inexperienced members, and consulting veterinarians

C10 Alcott

Detecting and Eliminating the Antecedents to Serious Programmatic Failure (Program Oversight Track) Linda N. Brovarney, Tanise L. Jackson, Brent C. MorseThe opportunities for failure in animal care and use programs are diverse, interactive and, at times, insidious. Early detection and preventive measures can be very rewarding. During this session, faculty and attendees will:• Highlight programmatic deficiencies, including inadequacies in IACUC oversight, as well as a wide variety of laboratory animal management and physical plant areas that have the capacity to impact animal health and welfare, the institution’s animal research endeavors, and overall programmatic quality negatively

• Address administrative problems, such as policies and procedures, that do not meet institutional requirements

• Share strategies and best practices for addressing these problems

C11 Commonwealth Ballroom B

Attaining a New Performance Plateau Through Post-Approval Monitoring (PAM) (Program Oversight Track) Christina Nascimento, Jon D. Reuter, Sandy WilkinsMany institutions are now embracing PAM as a useful means for assuring animal welfare and institutional compliance. However, there are no prescriptive regulatory expectations for PAM. During this session, faculty and attendees will:• Review the factors that can affect the success of a PAM program, including: an appreciation of the organizational philosophy and culture; the style, character, pertinent content, authority, and reporting structure of a PAM; and the collaborative engagement of scientific colleagues

• Discuss the facets of a successful PAM program from conception to delivery that can: assure the proficient and humane implementation of animal procedures in accordance with approved protocols; foster the continuing education of users; and integrate new techniques to benefit scientific outcomes

C12 Commonwealth Ballroom A

Auditing Outsourced Animal Activities(Program Oversight Track) Rachel Castillo, Paula Clifford, Ann JerniganDuring this session, faculty will:• Discuss the necessity of monitoring contract research organizations, specifically for welfare compliance

• Review how the auditing process should be managed, and discuss what to do with the results of an audit

• Outline how to prepare for audits, and review how laboratories are deemed acceptable for use

• Address how this type of monitoring differs from routine study monitoring or Good Laboratory Practices inspections

• Explore how academia interfaces with contract research organizations

C13 Harbor Ballroom I

The Analysis of Harm vs. Benefit (Protocol Review Track) Elizabeth Ford, Adam Shriver, Janet D. StemwedelDuring this session, faculty and attendees will:• Explore the ethical issues that may arise when an IACUC reviews a protocol and establishes of a threshold instigating formal harm benefit analysis

• Examine the ways an IACUC review can ensure both institutional compliance and ethical responsibility, while also facilitating research

• Discuss how to use standardized procedures to aid consistency and minimize repetition

• Review how a culture of welfare can promote a more rigorous harm/benefit review

C14 Harbor Ballroom II

Significant Changes: Development and Implementation of Policies and Guidance Documents for Principal Investigators(Protocol Review Track) George F. Babcock, Kelly A. Fusco, Mary Lou James, Elizabeth Meek (USDA resource person), Susan Silk In late August 2014, OLAW, in concurrence with the USDA, published a guidance document that allows institutions to develop policies and guidance documents permitting principal investigators to make some changes to their approved IACUC protocols utilizing administrative and veterinary consultation rather than IACUC review. During this session, faculty and attendees will:• Review the recent guidance by walking through the document

• Share strategies for the process of developing policies and guidance documents and how to implement them

• Provide insight on strategies that can be used to change protocols while also meeting the

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documentation standard of the guidance document

• Discuss how to create standard operating procedures for common experimental procedures, including the pros and cons of having pre-approved procedures

• Address what level of detail regarding standard operating procedures should be included in the protocol (i.e., do regulatory agencies allow protocols to refer to a specific standard operating procedure or should they be fully incorporated into the protocol?)

C15 Burroughs

Training and Assessment for IACUC Members and Staff (Qualifications and Training Track) Candice (CeCe) Brotchie-Fine, Nicole DuffeeDuring this session, faculty and attendees will:• Review and explore basic IACUC functions (PHS IV.B.1-8 and AWR 2.31.c.1-8)

• Examine the role and day-to-day work of the IACUC with experienced experts in the field

• Describe ways to ensure the IACUC is qualified through training, expertise, and/or the experience of IACUC members, including through the use of webinars and professional meetings, the Guide Training Treasures, AWA, etc.

• Discuss opportunities for continuing education of IACUC members

• Explore IACUC reviewer process assessment tools (e.g., reviewer report cards, protocol review turnaround times, etc.)

• Share ideas for new member training and continuing education of current members

12:15-1:15 PM Galleria HallLunch

12:15-1:15 PM Grand Ballroom CDResearch Ethics Book Group Lunch and Book Signing with Author and Henry Spira Memorial Lecturer Frans B. M. de Waal, PhD Participate in a vibrant discussion of The Bonobo and the Atheist: In Search of Humanism Among the Primates by author and Henry Spira Memorial Lecturer Frans B. M. de Waal, PhD, a biologist and primatologist known for his work on the behavior and social intelligence of primates. Attendees will have the opportunity to hear from and participate in discussion with Professor de Waal about his book and his work, and he will be available to sign books during this time. Professor de Waal’s book is available in print and for the Kindle through Amazon.com and copies will be available for purchase onsite.

1:30-2:45 PM Grand Ballroom ABPanel IV: Virtual IACUC: This Meeting Is in Session! Moderator: Mary Jo Shepherd Panelists: John F. Bradfield, Patricia A. Brown, Carol Clarke, Tammy Dellovade, Michael J. Huerkamp, Natalie L. Mays, Leo E. Otterbein, Janet D. Stemwedel Be sure not to miss this real-time virtual IACUC meeting! Virtual agenda items will be made available to conference attendees prior to the “meeting,” and attendees will have the opportunity to electronically participate in the virtual committee voting process via text or web polling. Audience vote tallies will then be displayed and discussed in real time, and representatives from AAALAC, NIH OLAW, and/or USDA, APHIS will provide their perspective on each issue discussed by the virtual IACUC. Items on the agenda may include the use of master protocols, single vs. social housing criteria, inappropriate satellite housing, and animal health monitoring issues.

2:45-3:00 PM Grand Ballroom FoyerBreak Join us for coffee and cold drinks.

3:00-4:15 PM Didactic Sessions and Workshops Series D

D1 Burroughs

Current Approaches to Administering Anesthetics and Analgesics: What’s New? What Works? What Doesn’t? (Animal Well-Being and the 3Rs Track) Barbara A. Garibaldi, Gordon Roble During this session, faculty will:• Consider IACUC methods for handling the assessment of pain management

• Review current methods for managing pain in laboratory animals

• Discuss how to maintain a surgical plane of anesthesia in rodents

• Outline the challenges of providing analgesia for immunological studies

• Explore current thinking on peri-operative pain management

• Define the circumstances and acceptable approaches for approval of nonpharmaceutical grade compounds use in experimental animals

D2 Commonwealth Ballroom C

Breeding Schemes in Rats and Mice: How to Avoid Overcrowding (Animal Well-Being and the 3Rs Track) Virginia L. Godfrey, Michael J. Huerkamp Many institutions use trio breeding in mice even though cage populations routinely exceed


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numbers compatible with the Guide’s space recommendations. However, the Guide also supports the use of performance metrics that produce acceptable results. This approach requires thought and careful ongoing navigation. During this session, faculty and attendees will: • Discuss the use of the performance approach in rodent breeding

• Address what to do when overcrowding happens as a result of a defective or disregarded performance approach

• Share innovative approaches and (dis)incentives used by programs to ensure consistently acceptable performance outcomes in rodent breeding colony management

D3 Harbor Ballroom I

Communicating With the Public About Animal Research (Hot Topics, Trends, and Special Issues Track) Allyson J. Bennett, B. Taylor Bennett, Paula Clifford, Alan B. Dittrich, Elizabeth Hodge, Ann T. Turner In the last decade, surveys have shown that public support for biomedical research with animal models has fallen. During this session, faculty and attendees will:• Review available resources, including recent polling data, for educating the public in an effort to provide a balanced understanding of the pros and cons of research with animals

• Discuss how best to provide the facts about why animals are used in research, what kind of care is provided to the animals during a research study, and what the benefits are for both humans and animals from this type of research

• Address where this communication is taking place today and how people can get involved with the process

• Explore strategies for effective communication, and approaches that derail communication

D4 Commonwealth Ballroom B

Open Forum for Laboratory Animal Veterinarians (Communication and Advocacy Track) Carol Clarke (USDA resource person), Elizabeth Ford, Scott E. Perkins Laboratory animal veterinarians in the United States are in a unique position compared to many of their colleagues in other countries in that they have been granted a tremendous amount of responsibility and authority for managing their institutions’ animal care and use programs. During this session, faculty and attendees will:

• Discuss the challenges that arise for veterinarians in exercising their responsibilities and authority

• Review suggestions for coping effectively with challenges to that authority

D5 Hancock

Reproducibility in Preclinical Studies: Understanding the Problem and What Your IACUC Can Contribute to the Solution (Hot Topics, Trends, and Special Issues Track) Steven M. Niemi, Susan Silk, Caroline ZeissThis session will inform attendees about recent findings and underlying causes regarding poor reproducibility of animal research results in the United States and elsewhere. Emphasis will be on options for investigator training so IACUC-approved experiments are more likely to be reproduced when performed by other scientists. During this session, faculty will: • Review current ideas regarding failures in reproducibility

• Provide insight on how IACUCs can facilitate reproducibility of preclinical studies

• Share strategies for training investigators in conducting reproducible studies using animal models

D6 Commonwealth Ballroom A

Issues Surrounding Euthanasia (Hot Topics, Trends, and Special Issues Track) Debra L. Hickman, Kathleen R. Pritchett-CorningDuring this session, faculty will:• Present some of the issues surrounding euthanasia that have arisen since the release of the latest American Veterinary Medical Association (AVMA) Guidelines

• Discuss how the current AVMA Guidelines can be updated to reflect new knowledge in the field

D7 Harbor Ballroom II

Double Down on IACUC Documentation: Forms, Minutes, and Record Keeping (IACUC Administration/Management and Process Track) Rob W. Anderson, Doreen H. Bartlett, Deb A. Frolicher, Elizabeth Meek During this session, faculty will:• Encourage attendees to take a fresh look at the rationale, requirements, and systems for IACUC documentation

• Examine strategies for reducing paperwork for self-imposed regulatory burden

• Share ideas regarding the preparation of minutes that meet requirements and ensuring they are FOIA-ready

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• Review best practices for developing, maintaining, and implementing these documents, including how to involve the research community in their development

• Discuss how to create user-friendly, customer-focused forms, guidelines, and policies that really work

D8 Harbor Ballroom III

Maintaining a Vital IACUC (IACUC Administration/Management and Process Track)Ann Jernigan, Jennifer A. Perkins, Mary Jo ShepherdDuring this session, faculty and attendees will: • Review how to recruit and retain good IACUC members

• Share strategies on how to keep IACUC members engaged

• Discuss how to create/maintain a climate where problems can be solved in partnership with researchers

• Consider how to promote dialogue and cultivate an IACUC whose members are able to work together while representing their distinct roles and constituencies

D9 Douglass

What to Do When Your Post-Approval Monitoring (PAM) Process Identifies Problems With the IACUC (IACUC Administration/Management and Process Track) Colleen A. Cody, Jo Ann Henry Attention is often focused on the principal investigator and the research staff when the PAM process identifies issues with compliance or proficiency. However, what do you do when the PAM process identifies the IACUC as the area that needs improvement? During a comprehensive audit, issues can be revealed related to a protocol’s content or review process, the inspection of a location, or IACUC member training. In addition, the IACUC may become aware of compliance or animal welfare concerns when a researcher voices dissatisfaction with the animal care and use program. During this session, faculty will: • Discuss how all of the teams may be evaluated in a PAM audit, including IACUC members and others

• Review the similarities and differences between the groups to develop a comprehensive, integrated, and consistent approach to PAM, including ways to improve IACUC member training

D10 Carlton

IACUC Challenges When Investigators Use Large Animal Models (Not Your Average IACUC Track) Larry Chapin, Adam Shriver, Michael Smith The use of large farm animals in research presents challenges not encountered when working with the commonly used laboratory animal species. During this session, faculty and attendees will:• Address facility management consideration of using farm animals

• Review the unique safety and hazard concerns encountered when using farm animals

• Discuss IACUC and welfare considerations encountered when using farm animals

D11 Otis

Occupational and Environmental Health and Safety Programs (Program Oversight Track) John F. Bradfield, Dara Kraitchman, Eileen M. Morgan Occupational and environmental health and safety programs are integral to animal care and use programs and are mandated by the PHS policy and the Guide. During this session, faculty will:• Explain the essential concepts in the creation, management, and monitoring of occupational and environmental health and safety programs

• Address various occupational and environmental health and safety issues to illustrate how the hazard survey and risk assessment processes influence occupational and environmental health and safety program intensity and complexity

• Review methods for creating and maintaining effective IACUC interactions

• Examine the roles of the principal investigator (scientific staff) and/or expert consultants in the optimization of occupational and environmental health and safety programs

• Provide information on how to identify and appropriately handle and track chemical and novel agents used in animals in research, handle cages, and deal with the waste stream

D12 Stone

Connecting the Committees: IACUC and IBC (Program Oversight Track) Mégan Losh, Natalie L. Mays, Alison D. PohlThis session will review the potential value inherent in a good IACUC/IBC partnership. As


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some of the regulatory issues governing the use of animals and the use of recombinant DNA overlap, it is important for the IACUC and IBC to combine forces and have a strong relationship. During this session, faculty and attendees will:• Review the regulatory overlap between the IACUC and the IBC

• Identify particular points in the process that increase burdens and that have no corresponding gain in ethical and regulatory compliant care and use of animals

• Share strategies for how to maximize the relationship between the IACUC and the IBC, including how an effective partnership can benefit each committee, principal investigators, and the institution

• Explore best practices with regard to the management of compliance committees, including how to manage information swiftly and effectively

D13 Alcott

Responding to Catastrophes: What Do You Do When it’s Not in Your Plan?(Program Oversight Track) James D. Macy, Jr., Peter Morgan, Jennifer K. PulliumDespite the very best planning efforts, formal disaster planning only goes so far. Will your program demonstrate resilience and flexibility when faced with an unexpected catastrophe and/or adverse event that is not included in your disaster plan? Using recent case studies, this session will review experiences and strategies for how to cope with rare, unexpected, and improbable situations. During this session, faculty and attendees will:• Review how to prepare for and manage the lockdown of facilities and satellite facilities caused by catastrophes

• Share strategies for preparing for and dealing with pandemics not included in the formal disaster plan

• Discuss how to prepare for and handle facilities when they become crime scenes

• Suggest strategies and resources useful for engaging, recruiting, coaching, and comforting personnel during uncertain, rapidly changing conditions

• Gain insights on how to manage the flow of information, media relations, and public perception during catastrophes

D14 Grand Ballroom E

Ensuring Congruency Between Grants and Protocols: Who, How, and When? (Protocol Review Track)Patricia A. Brown, Tanise L. Jackson, Justin A. McNulty, Samuel Varghese In this session, faculty will:• Define the requirements for congruence among grants, contracts, and protocols

• Discuss the various mechanisms for developing and implementing a program to accomplish this congruency, as well as to perform comparative reviews

• Identify the roles and responsibilities of the institution, the principal investigator, and the IACUC in facilitating compliance with grant policy

• Review the grant policy requirements of the NIH, National Science Foundation, Department of Defense, and VA as they relate to research, teaching, and testing of vertebrate animals

D15 Faneuil

Changing the Culture to Improve Compliance(Qualifications and Training Track) Anne Clancy, Rivka L. Shoulson During this session, faculty will:• Discuss the value of educated staff to the IACUC’s mission and responsibilities

• Explore how thinking outside the box keeps compliance inside the box

• Outline other ways to expand this program through subcommittees, subject matter experts, etc.

• Provide information on how to build a program from the ground up

D16 Adams

Time to Connect: A Conversation with AAALAC International (A Conversation With…Track) Christian E. Newcomer AAALAC International is a voluntary accrediting organization that enhances the quality of research, teaching, and testing by promoting humane, responsible animal care and use. It provides advice and independent assessments to participating institutions and accredits those that meet or exceed applicable standards. This interactive session will provide an opportunity for attendees to:• Ask questions of AAALAC International representatives

• Participate in an open discussion about issues relevant to AAALAC International stakeholders

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The USDA Animal Care Inspection Guide Revisions (Hot Topics, Trends, and Special Issues Track) In late February 2015, the USDA released a revised version of the inspection guidance used by USDA inspectors and the regulated community. During this session, faculty and attendees will:• Review the changes to the guide• Discuss the process for implementing these

changes during inspection, IACUC review, and in research facility annual reports

• Explore the Office of Inspector General (OIG) audit process and how the changes address the OIG audit recommendations

• Share strategies for how inspectors and those in the field can use the guidance to enhance the inspection process

• Review how the USDA guidance process works and how to provide feedback to USDA to help improve the process

4:15-4:30 PM Break


2015 IACUC Conference Town Hall MeetingModerators: F. Claire Hankenson, Christian E. Newcomer Do you still have a nagging question regarding animal care and use, the regulations, and/or IACUCs? Do you need further clarification on a topic? Did questions arise for you during the conference that you’d like to get addressed or did a topic come up in sessions you need more insight on? If so, join us for this closing general session where the conference co-chairs will review questions submitted by conference attendees throughout the meeting and have veterans in the field answer these questions and/or provide their insight. Attendees can submit questions starting on March 18 at 7:00 AM through March 20 at 12:15 PM via two question boxes stationed at the PRIM&R Help Desk. The co-chairs will review questions before the session and choose those that will be of interest to the larger group. Please note that, due to time, all questions might not be answered.

5:45-6:45 PM Grand Ballroom FoyerClosing Reception Join us for fond farewells and to make plans for the 2016 IACUC Conference. Light refreshments will be served.


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AEric Allen, CIP, CPIA Associate Director of Consulting Services, HRP Consulting Group, Inc. B7.Tim Allen, MS Technical Information Specialist, Animal Welfare Information Center, USDA, APHIS, Animal Care. A1. Rob W. Anderson, BS, LATG, CPIA Director of IACUC Office, University of Cincinnati. B3, D7. Michelle Aparicio, BS, CPIA Manager, IACUC and IBC, Research Compliance, North Shore-LIJ Health System, The Feinstein Institute for Medical Research. C9.Marc T. Avey, PhD Post-Doctoral Fellow, Ottawa Hospital Research Institute. C1. Chieko Azuma, DVM, PhD, DACVR, CPIA Specialist, IACUC/IBC, University of Massachusetts Medical School; Diplomate, American College of Veterinary Radiology (Radiation Oncology). A12.

BGeorge F. Babcock, PhD Professor; IACUC Chair, Department of Surgery, University of Cincinnati College of Medicine; Deputy Director of Research, Shiners Hospitals for Children. B4, C14. Philippe Baneux, DVM, DipECLAM Director; Attending Veterinarian, Center for Animal Resources and Education, Cornell University. B12.Szczepan Baran, VMD, MS Head, Innovative Animal Technologies and Training, Novartis Institutes for Biomedical Research, Inc. A13.Doreen H. Bartlett Senior Assurance Officer, OLAW, NIH. B17, D7.Allyson J. Bennett, PhD Assistant Professor, Psychology, University of Wisconsin—Madison. B3, D3. B. Taylor Bennett, DVM, PhD, DACLAM, DACAW Management Consultant and Senior Scientific Advisor, National Association for Biomedical Research. A4, B5, Panel III, C5, D3.Colleen Bennett, MS Manager, Oversight and Outreach for Animal Research, Wake Forest Medical Center, Wake Forest University School of Medicine. B15. Valerie K. Bergdall, DVM, DACLAM Director, University Laboratory Animal Resources; Attending Veterinarian; Professor, Clinical Veterinary Preventive Medicine, The Ohio State University. Panel I, A11, C2.Terry L. Blasdel, DVM IACUC Veterinarian, Division of Research, University of Houston. B6. John F. Bradfield, DVM, PhD, DACLAM Veterinarian; Senior Director, AAALAC International. IACUC 101, A5, Panel IV, D11.Natalie A. Bratcher, MS 3Rs Scientist; Alternatives Coordinator/Global Animal Welfare Coordinator, AbbVie, Inc. C1.Candice (CeCe) Brotchie-Fine, MA, CPIA Manager, Animal Welfare Compliance; IACUC Chair; Animal Welfare Officer, Novartis Institutes for Biomedical Research, Inc. C15. Linda N. Brovarney, BS, RVT, RLATG, CMAR, CPIA IACUC Director, University of California, San Francisco. C10. Marcy Brown, BS, MA, CPIA Animal Welfare Regulatory Compliance Lead, Pfizer Worldwide Research and Development. EIA, B8, C3.Patricia A. Brown, VMD, MS, DACLAM Director, OLAW, NIH. A7, B3, C6, Panel IV, D14. John A. Bryan, II, DVM, MS Public Service Assistant; Wildlife Veterinarian, University of Georgia College of Veterinary Medicine. B10, C8. Charles P. “Bud” Burnett, Jr., MHA, MSW, CPIA Executive Director, Division of Laboratory Animal Resources, University of Pittsburgh; President-Elect, Board of Directors, Three Rivers Branch AALAS. A14.

CDavid G. Cannon, CPIA IACUC Director, University of Alabama at Birmingham. B14.Darin S. Carroll, MS, PhD Acting Branch Chief, Poxvirus and Rabies Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention Keynote, March 19, Panel II.Rachel Castillo Animal Welfare Officer, Novartis Institutes for Biomedical Research, Inc. C12.Larry Chapin Research Assistant II, Department of Animal Science, Michigan State University. D10.Mark S. Christensen, MA Chair, Department of Philosophy; Associate Professor, Lourdes University; Unaffiliated/Nonscientist IACUC Member. C4.Anne Clancy, PhD Director, Animal Welfare Assurance, Massachusetts General Hospital. D15.Carol Clarke, DVM, DACLAM Research Program Manager, USDA, APHIS, Animal Care. A5, C9, Panel IV, D4. Paula Clifford, MLA, CVT, RLATG Executive Director, Pennsylvania Society for Biomedical Research; VP Operations, Animal Care Training Services. C12, D3.Colleen A. Cody, BS, CPIA Training and Compliance Program, New England Primate Research Center, Harvard Medical School. C4, D9.Jeremy T.H. Coleman, MS, PhD Wildlife Biologist; National White-Nose Syndrome Coordinator; Northeast Regional Wildlife Disease Coordinator, US Fish and Wildlife Service. Panel II.


faculty

DTammy Dellovade, PhD Head of Translational and Biomarker Research, Neurology Department, EMD Serono Research and Development Institute. B4, Panel IV.Frans B. M. de Waal, PhD Charles Howard Candler Professor of Primate Behavior, Psychology Department, Emory University; Director, Living Links Center, Yerkes National Primate Center. Henry Spira Memorial Lecture, Research Ethics Book Group Lunch.Alan B. Dittrich, PhD President, Massachusetts Society for Medical Research. D3. Nicole Duffee, DVM, PhD Director, Education and Scientific Affairs, AALAS. C15.

FMichael T. Fallon, DVM, PhD, DACLAM, CPIA Chief Veterinary Medical Officer, Office of Research and Development, VA. A15.Elizabeth Ford, DVM, MPVM, DACLAM Senior Director, The Scripps Research Institute. C13, D4.Brian Frederick, MS Assistant Operations Manager/Animal Specialist, Department of Systems Biology, Harvard Medical School; IACUC Member, Harvard Medical Area. A9.Deb A. Frolicher, BS, CPIA Director, IACUC Office, The Scripps Research Institute. EIA, A11, C7, D7.Kelly A. Fusco, CPIA Assistant Director, Compliance and Reporting, IACUC Office, Yale University. C14.

GBarbara A. Garibaldi, DVM, DACLAM Director, Animal Research Facility, Beth Israel Deaconess Medical Center. A1, B15, D1.Robert M. Gibbens, DVM Director, Animal Welfare Operations, USDA, APHIS, Animal Care. B5, C6, D17. Paula S. Gladue, VMD Veterinary Medical Officer, USDA, APHIS, Animal Care. B3.Virginia L. Godfrey, DVM, PhD Associate Director for Laboratory Services, Division of Laboratory Animal Medicine, University of North Carolina at Chapel Hill. D2. Elizabeth Goldentyer, DVM Director, Animal Welfare Field Operations, USDA, APHIS, Animal Care. A4, B17, C5, D17. Jamie Gothro, RVT, LATG, CMAR, CPIA Animal Welfare Officer/IACUC Administrator, VA San Diego Healthcare System. C9.Tina Grove, DVM, MS, DACLAM Staff Veterinarian, Laboratory Animal Resources, Princeton University. B6.

HF. Claire Hankenson, DVM, MS, DACLAM Director, Campus Animal Resources; Attending Veterinarian; Professor, Laboratory Animal Medicine, Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University. B2, Town Hall Meeting. Susan Harper, DVM, MS, DACLAM, DACVPM Veterinary Medical Officer, Office of Research Oversight, VA. A15.Emily Hearne, MS IACUC Training and Compliance Manager, Office of Animal Care and Use, University of North Carolina at Chapel Hill. B9.Tracy M. Heenan, DVM, CPIA Director, Office of Animal Care and Use; Associate Professor, University of North Carolina at Chapel Hill. B13.Lara A. Helwig, DVM, DACLAM Associate Director of Animal Care, Brown University. B13.Jo Ann Henry, LATG, CPIA Regulatory Compliance Coordinator, New York University Langone Medical Center, School of Medicine. D9.Debra L. Hickman, DVM, MS, DACLAM, DACAW Director, Laboratory Animal Resource Center; Associate Research Professor, Indiana University. D6. Elizabeth Hodge Director of Media, Foundation for Biomedical Research Media, Foundation for Biomedical Research. D3. Melinda B. Hollander, MS, CPIA IACUC Administrator; Animal Compliance and Training Officer, West Virginia University. Panel I, A7, B16.Alice Huang, PhD, CPIA Staff Scientist and Deputy for IACUC Guidance, Office of the Chief Veterinary Medical Officer, Office of Research and Development, VA. A15.Michael J. Huerkamp, DVM, DACLAM Director, Division of Animal Resources; Professor, Pathology and Laboratory Medicine; Attending Veterinarian, Emory University. Panel IV, D2.

JTanise L. Jackson, DVM, DACLAM, CPIA Director, Animal Welfare and Research Integrity, Florida A&M University. C10, D14.Mary Lou James, BA, LATG, CPIA Consultant, Regulatory Compliance; Research Animal Welfare, President, IACUC 101TM Series. IACUC 101, A6, C14.Donna Matthews Jarrell, DVM, DACLAM Attending Veterinarian; Director, Center for Comparative Medicine, Massachusetts General Hospital. A10, B7. Ann Jernigan, DVM, PhD, Dipl ACVCP Senior Vice President, Worldwide Comparative Medicine, Pfizer Worldwide Research and Development. C12, D8.


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KDara Kraitchman, VMD, PhD, FACC Cardiovascular Interventional Section Head, Division of MR Research; Professor, Department of Radiology, Johns Hopkins School of Medicine. A3, D11.

LChristian Lawrence Aquatic Resources Program, Boston Children’s Hospital. A9.David Lee-Parritz, DVM, DACLAM Director, Laboratory Animal Medicine Service; Clinical Professor and Chair, Department of Environmental and Population Health, Tufts University School of Veterinary Medicine. A2, B12.Jori K. Leszczynski, DVM, DACLAM Director for the Office of Laboratory Animal Resources; Assistant Professor, Department of Pathology, University of Colorado Denver. A14, Panel III, C5.Sally E. Light, BA, CPIA IACUC Administrator, Michigan State University. Panel I, B12, C3. Jennifer Lofgren, DVM, MS, DACLAM Clinical Assistant Professor, University of Michigan Medical School. A2.Mégan Losh, MPA, CPIA Manager; School of Medicine IACUC, Office of Research Compliance, Office of Vice President for Research, Indiana University. B14, D12. David J. Lyons, BA, PhD Director, Animal Care and Use Program, Wake Forest University School of Medicine. B15, Panel III, C5.

M James D. Macy, Jr., DVM Professor, Comparative Medicine; Vice Chairman, Clinical Affairs, Comparative Medicine; Attending Veterinarian; Director, Yale Animal Resources Center, Yale University. C2, D13. Nancy Figler Marks, DVM, MS, DACLAM IACUC Office Director; Veterinarian, University of Iowa. A12. Natalie L. Mays, BA, LATG, CPIA Director of the IACUC and IBC, New York University Langone Medical Center. B7, Panel IV, D12. Monte Matthews, BA, CPIA Director, Animal Care Services, University of Oregon. IACUC 101, A6.Justin A. McNulty, CPIA, MLAS, RLATG IACUC and IBC Senior Program Coordinator, University of Texas at Austin. B11, D14. Letty V. Medina, DVM, DACLAM Associate Director, Animal Welfare and Compliance, AbbVie, Inc. C1. Elizabeth Meek, DVM, MPH Assistant Regional Director, Western Office, USDA, APHIS, Animal Care. A7, B9,C14, D7.David K. Meyerholz, DVM, PhD, DACVP, DACVM Director, Division of Comparative Pathology; Associate Professor, Department of Pathology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa. Keynote, March 19 (afternoon). Eileen M. Morgan, BS Director, Division of Assurances, OLAW, NIH. B11, C9, D11. Peter Morgan, BA, LATG Associate Director, Vivarium Operations Laboratory Animal Services, Novartis Institutes for Biomedical Research, Inc. D13. Joanne Morris, DVM, DACLAM Clinical Veterinarian, Center for Comparative Medicine, Massachusetts General Hospital. A8. Brent C. Morse, DVM, DACLAM Animal Welfare Program Specialist, Division of Compliance Oversight, OLAW, NIH. A5, B17, C10. Rachel A. Murray, MS, CPIA, RLATG Research Compliance Specialist, Cincinnati Children’s Hospital Medical Center. B8.

NChristina Nascimento, CPIA, MS IACUC Manager, Office of Research Compliance, Brigham and Women’s Hospital. A10, C11.Christian E. Newcomer, VMD, MS, DACLAM Executive Director, AAALAC International. A11, D16, Town Hall Meeting.Sarah Newman, PhD Training Coordinator, Research Animal Resources Center, University of Wisconsin Madison. B16.Steven M. Niemi, DVM Director, Office of Animal Resources, Harvard University. A11, C3, D5.

OLeo E. Otterbein, PhD Associate Professor of Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center. Panel I, Panel IV.

PValerie Parkison, MS IACUC/IBC Regulatory Director, Tufts University. C6.Jennifer A. Perkins, MA, CPIA Director, Office of Animal Research Oversight, University of California, Los Angeles. A12, D8. Scott E. Perkins, VMD, MPH, DACLAM Senior Director, Division of Laboratory Animal Medicine, Tufts University. B2, D4. Angela J. Phillips, RVT, LAT, CPIA Protocol Consultant, The Ohio State University. B14. Marky Pitts, CPIA IACUC Advisor; PRIM&R Representative; AAALAC International Board of Trustees. IACUC 101, A6.Alison D. Pohl, MS, RLATG, CPIA Research Compliance Monitor; IACUC Administrator, University of Connecticut Health Center. D12.Felicia Ponce, CPIA, CMAR, RLATG IACUC Coordinator I, Texas Biomedical Research Institute. B8.


faculty

Patricia A. Preisig, PhD Professor, Internal Medicine and Cellular and Molecular Physiology; IACUC Chair, Yale University. A14.Kathleen R. Pritchett-Corning, DVM Senior Clinical Veterinarian, Faculty of Arts and Sciences, Harvard University. B1, D6. Stacy Pritt, MS, DVM, MBA, CPIA, DACAW Director, IACUC, University of Texas Southwestern Medical Center at Dallas. A9.Gina R. Prochilo-Cawston, MS, CPIA, PMP Senior Research Compliance Specialist, Office of Compliance and Business Conduct, Beth Israel Deaconess Medical Center. C1. Jennifer K. Pullium, MVB, DACLAM Director, Division of Laboratory Animal Resources; Associate Professor, Pathology, New York University Langone Medical Center, School of Medicine. D13.

RJon D. Reuter, DVM, MPVM, DACLAM Senior Staff Scientist; Attending Veterinarian; Senior Director of Animal Resources, Salk Institute for Biological Studies; Visiting Scholar, University of California, San Diego. A13, B6, C11.Joan T. Richerson, MS, DVM, MS, DACLAM, CPIA Assistant Chief Veterinary Medical Officer, Office of the Chief Veterinary Medical Officer, Office of Research and Development, VA. A15.Gordon Roble, DVM, DACLAM Clinical Veterinarian; Research Assistant Professor, New York University School of Medicine. D1.Kenneth M. Rosen, PhD Director of Research; Principal Scientist, BioAxone BioSciences, Inc. A3.

SRebecca Saez, PhD, CPIA Compliance and Training Coordinator, Columbia University. C7. Mary Jo Shepherd, DVM, CPIA Executive Director of the Office of the IACUC, Columbia University. EIA, B9, C6, Panel IV, D8.Rivka L. Shoulson, DVM, MPH Chief of Quality Assurance and Training; Clinical Veterinarian, Columbia University Medical Center. D15. Adam Shriver, PhD Postdoctoral Fellow, Department of Medical Ethics and Health Policy, University of Pennsylvania School of Medicine. C13, D10.Robert S. Sikes, PhD Professor of Biology, Behavioral and Evolutionary Ecology; Director, Basic Animal Services Unit, University of Arkansas at Little Rock; Chair, Animal Care and Use Committee; President-Elect, American Society of Mammalogists. A8, Panel II, B10, C8.Susan Silk, MS Director, Division of Policy and Education, OLAW, NIH. IACUC 101, B17, C14, D5.William Singleton, DVM, DACLAM Training Consultant, Animal Care Training Services. A13.David K. Skelly, PhD Professor of Ecology, School of Forestry and Environmental Studies, Yale University; Director, Peabody Museum of Natural History. Panel II. Michael Smith, DVM Veterinarian, USDA, APHIS, Animal Care. A6, B13, D10.Margaret D. Snyder, PhD Office of Extramural Research FOIA and Privacy Coordinator, NIH. A4, C5.Janet D. Stemwedel, PhD Associate Professor, Department of Philosophy, San José State University. C13, Panel IV.

TVenita B. Thornton, DVM, MPH Senior Assurance Officer, OLAW, NIH. B13.Joseph D. Thulin, DVM, MS, DACLAM Director, Biomedical Resource Center, Medical College of Wisconsin. A11.Tanya Tims, DVM Supervisory Veterinary Medical Officer, USDA, APHIS, Animal Care. IACUC 101, B17, D17.Ann T. Turner, PhD, FASAE, CAE Executive Director AALAS and the AALAS Foundation; IACUC Member, University of Tennessee Health Sciences Center. D3.

VSamuel Varghese, PhD Director of IACUC and IBC, Office of Research, University of Massachusetts Medical School. D14.Mary Ann Vasbinder, DVM, DACLAM Head, Corporate 3Rs and Training Strategy, GlaxoSmithKline. C1.

WSandra L. Wilkins, LVT, RLATG, CPIA IACUC Research Liaison, Animal Care Program, Michigan State University. C11.Sabune Joane Winkler, JD Director, Regulatory Affairs Operations, Harvard School of Public Health. B11.Axel V. Wolff, MS, DVM Director, Division of Compliance Oversight, OLAW, NIH. A4, B9, C5.

ZCaroline Zeiss, PhD, BVSc, DACVP, DACLAM Professor, Comparative Medicine, Yale University School of Medicine. D5.


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Plenary and Keynote Biographiesfa

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B. Taylor Bennett, DVM, PhD, DACLAM, DACAW, currently serves as the senior scientific advisor for National Association for Biomedical Research. He spent 36 years at the University of Illinois at Chicago overseeing their animal care and use program. The last 10 of those years he served as the associate vice chancellor for research resources and, in that role, he was responsible for 14 campus-wide core research support services. Dr. Bennett obtained his Doctor of Veterinary Medicine degree from Auburn University and his PhD from the University of Illinois Medical School. Dr. Bennett has been active in a variety of professional organizations and currently serves on the Board of Directors of the Scientist Center for Animal Welfare and as chair of the Board of the ASLAP Foundation. Dr. Bennett is a member of the 2015 IACUC Conference Planning Committee.

Valerie K. Bergdall, DVM, DACLAM, serves as the attending veterinarian and a professor in clinical veterinary preventive medicine at The Ohio State University (OSU). Dr. Bergdall became the director of the centralized biomedical animal facilities at OSU in 2007, and currently oversees a staff of six veterinarians and approximately 75 animal care staff. She received her veterinary degree at Purdue University, completed a residency in laboratory animal medicine at the University of Michigan, and joined OSU in 1994. Dr. Bergdall is actively engaged in a Working Group of ACLAM Diplomates addressing the regulatory burden associated with the animal care and use program, and co-authored a recent editorial in The FASEB Journal on this subject. Her firsthand experience in dealing with fallout from the “Age of Enforcement” and a public institution’s response to this scrutiny lend insight into the development of self-imposed regulatory burden. In addition, she serves as an AAALAC ad hoc consultant, and study section grant reviewer for NIH’s STOD division. In her spare time, she can be found rollerblading at the local metro parks or walking her golden retriever—both at the same time just did not work!

John F. Bradfield, PhD, DVM, DACLAM, is a veterinarian and the senior director of AAALAC International. In his current role at AAALAC International, Dr. Bradfield is responsible for education and outreach activities. Dr. Bradfield has many years’ experience with the accreditation process including as an ad hoc consultant, 10 years’ service as a council member of AAALAC International, and as council president. He has served as director of the division of laboratory animal medicine and attending veterinarian at the University of North Carolina at Chapel Hill, and also as chair of the department of comparative medicine at The Brody School of Medicine at East Carolina University in Greenville, NC. He has extensive experience in academic laboratory animal medicine, managing animal programs, and working with animal care and use committees. Prior to his career in laboratory animal medicine, Dr. Bradfield was a large animal practitioner. Dr. Bradfield earned his PhD in experimental pathology and has authored scholarly publications in various areas of laboratory animal medicine, wound healing, and vascular and platelet biology.

Patricia A. Brown, VMD, MS, DACLAM, currently serves as the director of OLAW at NIH. OLAW oversees the use of animals in NIH-supported biomedical and behavioral research by providing guidance on and interpretation of the US PHS Policy on Humane Care and Use of Laboratory Animals (PHS Policy); monitoring

compliance with the PHS Policy; evaluating all allegations or indications of noncompliance with federal animal welfare requirements; and supporting educational programs that further the humane care and use of research animals. She received her Bachelor of Science in animal science from The Pennsylvania State University and her veterinary degree from the University of Pennsylvania. She served in the US Air Force for eight years and, while on active duty, earned a Master of Science in laboratory animal medicine from the Pennsylvania State Milton S. Hershey Medical Center. Dr. Brown joined the NIH in 1986, and has since served in clinical and management positions in the Veterinary Resources Branch, the National Cancer Institute, and the Office of Animal Care and Use, before joining OLAW in 2006 as the director.

Darin S. Carroll, MS, PhD, is the acting branch chief at the poxvirus and rabies branch in the division of high-consequence pathogens and pathology at Centers for Disease Control and Prevention. His primary area of interest is the ecology and evolution of zoonotic diseases with mammalian hosts. He has participated in disease outbreak and surveillance investigations of arenaviruses, hantaviruses, Ebola, monkeypox, and Nipah virus. His research emphasis is on increasing the knowledge of the ecology and evolution of viral zoonoses and their associated hosts in order to better predict outbreaks and identify means of decreasing human exposure risks. Dr. Carroll earned his PhD in biology from Texas Tech University.

Carol Clarke, DVM, DACLAM, is the research program manager at the USDA, APHIS, Animal Care. Dr. Clarke received her bachelor’s degree in the natural sciences from The Johns Hopkins University and her DVM from the Tuskegee University School of Veterinary Medicine. After receiving her DVM, Dr. Clarke practiced small animal medicine in New York City, NY, for 13 years before entering the laboratory animal medicine training program at SmithKline Beecham Pharmaceuticals. Upon completion of the program, she joined the NIH in 1998 as the primate facility veterinarian for the Veterinary Resources Program. In 2001, she accepted a position with the Comparative Medicine Branch of the National Institute of Allergy and Infectious Diseases (NIAID) and became a Diplomate of ACLAM in 2005. During her 10 years with NIAID, she served as IACUC coordinator, vice chair of the rodent gnotobiotic committee, and chief of shared and central facility operations. In addition, she prepared all USDA, OLAW, and AAALAC annual reports. Dr. Clarke accepted a position with USDA in 2011. Dr. Clarke is a member of the 2015 IACUC Conference Planning Committee.

Jeremy T.H. Coleman, MS, PhD, is a wildlife biologist with the US Fish and Wildlife Service (USFWS), stationed at the Northeast Regional Office in Hadley, MA. Dr. Coleman is also the national white-nose syndrome coordinator and the Northeast regional wildlife disease coordinator for USFWS. He received a BA in anthropology from Colgate University, and a MS and PhD in wildlife science from the department of natural resources at Cornell University. Dr. Coleman’s research interests are largely in organismal and applied ecology, including animal behavior and wildlife disease, and in wildlife conservation.


faculty

Frans B. M. de Waal, PhD, is a Dutch/American biologist and primatologist known for his work on the behavior and social intelligence of primates. He is the Charles Howard Candler Professor in the psychology department of Emory University, and director of the Living Links Center at the Yerkes National Primate Center. His first book, Chimpanzee Politics (1982), compared the schmoozing and scheming of chimpanzees involved in power struggles with that of human politicians. Dr. de Waal’s scientific work has been published in hundreds of technical articles in journals such as Science, Nature, and Scientific American, as well as outlets specialized in animal behavior. His popular books have been translated into many languages, making him one of the world’s most visible primatologists. His most recent books include: The Age of Empathy (Harmony, 2009) and The Bonobo and the Atheist (Norton, 2013). Dr. de Waal has been elected to the National Academy of Sciences, the American Academy of Arts and Sciences, and the Royal Dutch Academy of Sciences. In 2007, he was selected by Time as one of “The Worlds’ 100 Most Influential People Today,” and, in 2011, was selected by Discover as among “47 (all time) Great Minds of Science.”

Tammy Dellovade, PhD, is the head of translational and biomarker research in the neurology department at EMD Serono Research and Development Institute. Dr. Dellovade has extensive experience building and leading in vivo pharmacology teams to support development of small molecule and protein/peptide therapeutics in the area of neurology and neurodegeneration. Her leadership experience includes establishing and managing animal facilities, as well as serving as an IACUC chair. Prior to joining EMD Serono in 2009, Dr. Dellovade held positions at Merck Research Laboratories, Curis, Inc., and Wyeth Pharmaceuticals. She earned her PhD degree in biology from the University of Virginia.

F. Claire Hankenson, DVM, MS, DACLAM, is the director within Campus Animal Resources and the attending veterinarian at Mich-igan State University. In addition, she is a professor of laboratory animal medicine in the department of pathobiology and diagnostic investigation at the College of Veterinary Medicine. Dr. Hankenson obtained her veterinary degree from Purdue University. Following veterinary school, she completed her laboratory animal medicine residency and graduate work (MS, Microbiology) at the University of Washington, Seattle. She became a Diplomate of ACLAM in 2002. Dr. Hankenson’s current position combines administrative service, regulatory input, clinical effort, and collaborative research. Her own research studies involve investigations of refinements in the care and use of laboratory rodents, particularly blood sampling, tail biopsy evaluations, and humane endpoints. Dr. Hankenson has been active on committees within AALAS since 2002, serves on the Executive Board for ACLAM, and is an ad hoc consultant to AAALAC, International. Dr. Hankenson is co-chair of the 2015 IACUC Conference Planning Committee.

Melinda B. Hollander, MS, CPIA, is the IACUC administrator and animal compliance and training officer at West Virginia University, and is currently co-chair of the Kuali Coeus IACUC sub-committee at the Kuali Coeus Foundation. In her role as the IACUC administrator, Ms. Hollander manages the review and approval process for animal use protocols, conducts pre-reviews of animal use protocols, communicates with external agencies, and assists researchers with completion of their animal use protocols. In

addition, in her role as the animal training and compliance officer, she coordinates all animal-related training and ensures compliance with all relevant regulations. Ms. Hollander received bachelor’s and master’s degrees in kinesiology and physiology, respectively, from the University of Wisconsin—Madison. She has also received her CPIA certification. Prior to her role as the IACUC administrator and animal compliance and training officer, Ms. Hollander established and ran the Animal Models and Imaging Facility at West Virginia University. This role afforded her experience as an animal user, which is of great benefit in her current role when dealing with researchers. Ms. Hollander a member of the 2015 IACUC Conference Planning Committee.

Michael J. Huerkamp, DVM, DACLAM, is currently the director of the division of animal resources at Emory University where he holds the academic rank of professor in the department of pathology and laboratory medicine, and where he serves as attending veterinarian. Dr. Huerkamp is a 1984 graduate of the College of Veterinary Medicine at The Ohio State University and a Diplomate of ACLAM. He has gained extensive research support, animal resources program management, and IACUC experience at Emory University and through affiliation with several other institutions, and he serves as an ad hoc specialist for AAALAC International.

Jori K. Leszczynski, DVM, DACLAM, is the director of the office of laboratory animal resources and a veterinarian at the University of Colorado Denver, and an assistant professor in the department of pathology in the School of Medicine. Dr. Leszczynski attended The Ohio State University for her bachelor’s and veterinary degrees, performed her residency in laboratory animal medicine at the University of Illinois at Chicago, and became a Diplomate of ACLAM in 2004. In 2002, Dr. Leszczynski became assistant director of the biological resources unit at the Cleveland Clinic Foundation, and was named associate director in 2004. In 2006, she became the director and attending veterinarian of the Biological Resources Center at National Jewish Health and, in 2009, she moved to her current position. In 2013, Dr. Leszczynski was named the interim director and attending veterinarian at the University of Colorado Boulder to oversee a complete reorganization of their animal program, as well as to assist them with addressing regulatory compliance issues. Dr. Leszczynski has served on several committees for ACLAM and ASLAP, where she served on their Board of Directors. She served as president of AALAS’ Mile High Branch in 2009, and she currently is on AALAS’ Institute for Laboratory Animal Management Committee. Dr. Leszczynski is a member of the 2015 IACUC Conference Planning Committee.

Sally E. Light, BA, CPIA, has been the IACUC administrator at Michigan State University (MSU) since 2005. Previously, she was the administrator for the Office of Clinical Research in the College of Veterinary Medicine and an administrator at the Diagnostic Center for Population and Animal Health at MSU. Ms. Light received her bachelor’s degree from Pennsylvania State University. She has published in Lab Animal, facilitated workshops at PRIM&R conferences, and presented at Big Ten IACUC Conferences and IACUC Administrator’s Best Practices on IACUC Issues. In addition to serving on MSU committees, she is a Kuali Coeus Community IACUC subcommittee subject matter expert.


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David J. Lyons, PhD, is director of the Wake Forest Animal Welfare Program and the IACUC. As Wake Forest’s first full-time director, he partnered with leadership to advance an overall quality assurance program and create a paperless committee review process. He also co-authored the training tool, An IACUC Member’s Guide to Animal Facility Inspections, housed at the NIH’s Office of Research Integrity. He received his BS from Pennsylvania State University in molecular and cellular biology, and completed his PhD in behavioral neuroscience at Boston University. After a post-doctoral fellowship at Harvard Medical School, he conducted research investigating the neural basis of substance abuse in animals at the Wake Forest School of Medicine. In 2001, he left the laboratory and became an administrator in the Office of Research at Wake Forest School of Medicine. Between 2001 and 2007, he wore different hats as a grants administrator, interim director of industry relations, and strategic planner, prior to taking on his current role in animal research oversight.

Natalie L. Mays, BA, LATG, CPIA, is the director of the office of the IACUC and IBC at New York University Langone Medical Center (NYULMC). In this position, she is responsible for the administrative management of the IACUC and IBC. Prior to joining the team at NYULMC, Ms. Mays was the IACUC director at Columbia University and Columbia University Medical Center. She has served on IACUCs since early 1988 in various capacities, including in the role of regulatory compliance and training coordinator. Ms. Mays received her bachelor’s degree in microbiology from Miami University in Oxford, OH, is a graduate of AALAS’ Institute for Laboratory Animal Management program, obtained a LATG from AALAS and CPIA certification from PRIM&R. She has been active in AALAS at the local and national levels serving on various committees. She is a member of PRIM&R’s Diversity Advisory Group and the 2015 IACUC Conference Planning Committee.

David K. Meyerholz, DVM, PhD, DACVP, DACVM, is a boarded veterinary pathologist and microbiologist (virologist) who serves as director of the division of comparative pathology and associate professor in the department of pathology at the University of Iowa Roy J. and Lucille A. Carver College of Medicine. His scientific interests are centered on lung diseases, especially that of cystic fibrosis. He has served as lead pathologist and key investigator in the study of novel cystic fibrosis animal models that were developed at the University of Iowa over the past eight years. He has over 100 papers published, including in the leading translational journals (e.g., Nature Medicine, Science Translational Medicine, etc.), and recently co-authored a review on the development of early cystic fibrosis lung disease in The New England Journal of Medicine. He is particularly interested in phenotypic analyses and pathologic studies on the cystic fibrosis model tissues, and translating these findings to understand the human condition.

Christian E. Newcomer, VMD, MS, DACLAM, joined AAALAC International as the executive director in 2008, and had participated in AAALAC’s peer review activities since 1983. He is a 1977 graduate of the School of Veterinary Medicine at the University of Pennsylvania. Following a year in a large animal internship at The Pennsylvania State University (1977-78), he entered post-doctoral training in laboratory animal medicine at the University of Michigan (1978-81) and became board certified as a Diplomate in ACLAM in 1982. Prior to his appointment at AAALAC International, he held academic and leadership positions in laboratory animal medicine at the Massachusetts Institute of Technology (1981-87), Tufts-New England Medical Center (1987-1994), University of North Carolina at Chapel Hill (1994-2001), the Veterinary Resources Program at the NIH (2001-2003), and The Johns Hopkins University (2003-2008). He is a past-president of the ACLAM (1996) and of AALAS (2008). He has also authored articles and spoken widely on many topics to promote the quality of care of research animal subjects. Dr. Newcomer is a member of PRIM&R’s Board of Directors, and co-chair of the 2015 IACUC Conference Planning Committee.

Leo E. Otterbein, PhD, is currently an associate professor at Harvard Medical School, and is a member of the department of surgery and The Transplant Institute at Beth Israel Deaconess Medical Center (BIDMC), where he has been since 2004. He trained at The Johns Hopkins University and Yale University between 1996 and 2001 before accepting his first faculty position at the University of Pittsburgh School of Medicine in 2001. Dr. Otterbein runs a basic research laboratory and is funded by the NIH with an interest on innate immunity and oxidative stress. His research pioneered the use of carbon monoxide for medical benefit when administered at low concentrations, and his work directly led to clinical trials in organ transplant recipients. He is the BIDMC IACUC chairman and site miner for the Boston-based Center for the Integration of Medicine and Innovative Technology and Boston Biomedical Innovation Center. He has spent over a decade as a reviewer for the NIH, the American Heart Association, and numerous international agencies, and has more than 100 publications in high impact journals.

Mary Jo Shepherd, DVM, CPIA, is currently the executive director of the office of the IACUC at Columbia University. In this position she administers two IACUCs for a large animal care and use program. She has served on IACUCs since early 1988 and was a member of five IACUCs for a number of years while serving as attending veterinarian for a privately owned medical device testing laboratory. She has spent more than eight years working in the pharmaceutical industry. Dr. Shepherd is involved with PRIM&R, has been active in AALAS at the local and national levels, and currently serves on AALAS’ Editorial Review Board. She has been actively involved in the planning of the New Jersey Association for Biomedical Research’s annual IACUC conference for more than 11 years, and was also on the Americans for Medical Progress Board of Directors for five years. Dr. Shepherd was a recipient of PRIM&R’s 2012 Distinguished Service Award, and is a member of the 2015 IACUC Conference Planning Committee.


faculty

Robert S. Sikes, PhD, is a professor of biology and director of the basic animal services unit at the University of Arkansas at Little Rock. He currently serves as vice president of the American Society of Mammalogists and is president-elect, and he chairs the animal care and use committee for that organization. His background and research experience are exclusively with wild vertebrates, both in the field and in captivity. Professor Sikes is a member of the 2015 IACUC Conference Planning Committee.

David K. Skelly, PhD, is director of the Peabody Museum of Natural History and professor of ecology at the School of Forestry and Environmental Studies at Yale University. Prior to assuming the Museum directorship, he served for five years as associate dean for research in forestry. He also holds an adjunct appointment in the department of ecology and evolutionary biology. Professor Skelly is a field biologist whose research focuses primarily on the ecology and development of amphibians. He has authored more than 80 papers, and his work on the effects of water pollution on the development of frogs in suburban environments has received wide attention in the national media. Professor Skelly has held a Guggenheim Fellowship and is a fellow of the American Association for the Advancement of Science. He has been awarded the Forestry School’s annual prize for teaching excellence on four occasions. Professor Skelly received his BA from Middlebury College, his PhD in biology from the University of Michigan, and he held postdoctoral fellowships at the University of Wollongong, Australia, and the University of Washington before joining Yale’s faculty in 1996.

Janet D. Stemwedel, PhD, is an associate professor of philosophy at San José State University (SJSU). Her teaching and research focus on philosophy of science and ethical issues in scientific research. Dr. Stemwedel has served as the non-scientist member of SJSU’s IACUC since 2007, and became director of the SJSU Center on Ethics in 2013. She also writes about the ethics of animal research on the popular blogs Doing Good Science (blogs.scientificamerican.com/doing-good-science/) and Adventures in Ethics and Science (ethicsandscience.scientopia.org/). She received a bachelor’s degree in chemistry and philosophy from Wellesley College (1989), and doctorates in physical chemistry (1994) and philosophy (2001) from Stanford University. Dr. Stemwedel is a member of the 2015 IACUC Conference Planning Committee.

Recognition






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Posters Selected for Presentation

PRIM&R is pleased to present the IACUC Conference Poster Presentation Program at the 2015 IACUC Conference. Seventeen posters* were selected for display throughout the conference. Posters are on display in the Commonwealth Foyer at the Westin Boston Waterfront Hotel, and may also be accessed via the conference website. Many thanks are owed to the Planning Committee for their work in coordinating the Poster Presentation Program.

1. A Global Approach to Building a Positive Reinforcement Training Program for Research Animals Donna Church; Melissa Dragon; Jay Fortner; Claudine Fredette; Kristen Giordano; Lauren Kelley; Zoltan Nagy; Stella Rapa; Susan Rubino; Ronelle Savoie; Brett Sylvester; LaWanda Thompson Pfizer, Inc.

2. A Survey of Animal User Training Programs Across Academia, Industry, and Medical Centers Gina Prochilo-Cawston, MS, CPIA, PMP Beth Israel Deaconess Medical CenterCarolyn Brown, CPIA Boston UniversityDotty Paquin, MBA, BS, CMAR, LATG, CVT Pfizer, Inc.

3. Association of Primate Veterinarians Nonhuman Primate Housing Survey B.Taylor Bennett, DVM, PhD, DACLAM, DACAWNational Association for Biomedical Research

4. Continuing Education for IACUC Members Amy F. Kilpatrick, BA, RLATG, CVT; Alison Hayward, DVM CBSET, Inc.

5. Current and Prospective Status for Scientific Research on Fish Welfare in Egypt Khadiga Gaafar; Kareem Morsy; Sohair Fahmy; Abeer Badr; Amel Soliman; Rewaida Abdel-Gaber; Ibrahim Abdelkader; Kohar Garo Varjabedian; Mervat Zaghloul; Hoda Saady; Abdel-Base Aref; Fathy Abdel-Ghaffar; Sayed Fahim; Ahmed AfifiCairo University

6. Development of a Novel Collaborative China Animal Ethics CommitteeSherry Vaughn, DVM; Yibo Kong; Terri L. Vandegiessen, BS, CPIA; Torrie L. Condet, BS, MS; John Hallberg, DVM, PhD; JinAn Huang, DVM, PhD; Yibo Kong, DVM, MS; Cheng Song, DVM, PhD; Wei Wang, DVM, PhD; Zhenqin Wang, DVM, MS; Guicai Xu, DVM, MS Zoetis

7. Establishing an Agricultural Animal Care and Use Committee: All Hands on Deck!Kristen M. Brennan, PhD; Ryan Samuel, PhD; Jeannine Osborn, CPIA; Matthew Simpson; Kenneth Dickey, DVM; Kate Jacques, PhD Alltech Inc.

8. Evaluation of Electronic Database Solutions for IACUC Operations Sally Thompson-Iritani; Elliott Walker; Virginia Thomas; Laury Istvan University of Washington

9. From AAALAC Trends to a Complete Occupational Health and Safety Program Elizabeth Rivera, DVM; Idia V. Rodriguez, DVM; Frances Candelas, BS, BVTUniversity of Puerto Rico, Medical Sciences Campus

10. Implementing an Animal Welfare Quality Monitoring Program for Third Parties Toni Albanese Bristol-Myers SquibbKimberly Frazier, MS; Sherry Vaughn, DVMZoetis

11. Post-Approval Monitoring: Making it StickMichelle Martin, BES, RVT, RLAT; Emi Yano, PMP, B.Ed; Rhain Louis, BSc, MScUniversity of Toronto

12. Postural Movements of Rabbits in Variable Height Caging Curtis Schondelmeyer; Laura Fontaine; N. Reynolds; K. Yip; Amy SchadeToxikon Corporation

13. “Readiness Rounds”: Involving the Technical Staff in Post Approval Monitoring Josh Folden, RALAT, BS; Marcy Brown, BS, MA, CPIA Pfizer, Inc.

14. Scripting the Way for Rodent Procedure Recordkeeping Compliance Erica Armstrong, BS, CPIA; Daphne Molnar, MBA, CPIA, CMAR Vanderbilt University

15. Table Topics: A No-Cost IACUC Member Continuing Education Program Candice (CeCe) Brotchie-Fine, MA, CPIA Novartis Institutes for Biomedical Research

16. The Road to Success: Rolling Out Electronic Animal Study Protocol SoftwarePaul Mireles, RLATG, CPIA; Mandy Kozlowski, BA, CPIA; Jesse Funk; Russell Greene, BS Northwestern University

17. TESS: Tools to Enhance Surgical Success Colleen Bennett, MS; David J. Lyons, PhD Wake Forest School of Medicine PRIM&R is pleased to feature this poster in a breakout session during the conference: B15 (workshop): Poster Presentation: Tools for Enhancing Surgical Success (TESS) on March 19 from 4:00 to 5:15 PM. Please see the conference schedule for more information.

*Please note, the inclusion of posters featuring commercial products should not be considered an endorsement by PRIM&R.

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Supporters & Exhibitors


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PRIM&R thanks our Supporters and Exhibitors!While onsite at the conference, please be sure to visit with our Supporters and Exhibitors in the Commonwealth and Grand Ballroom Foyers during the following hours:

Wednesday, March 185:00-6:30 PM

Thursday, March 197:00 AM-6:30 PM

Friday, March 207:00 AM-3:00 PM

Supporters & Exhibitors: Concourse Level

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Table Organization

1 IRBNet2 Lovelace Respiratory Research Institute3 NTM, Inc.4 CITI Program5 InfoEd Global6 iMedRIS Data Corporation7, 8 Key Solutions, Inc.9, 10 a-tune software, Inc.11 Questx12, 13 Huron Consulting Group14, 15 TOPAZ Technologies, LLC16 The BeFreegle Foundation17 AALAS18 AAALAC International19 USDA, APHIS, Animal Care20 CPIA® Program21 PRIM&R

Supporters and Exhibitors: Concourse Level


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a-tune software, Inc. 512.243.8539 | www.a-tune.comTables: 9 and 10a-tune’s software medical research suite, tick@lab, provides compliance management for IACUCs, IRBs, and IBCs. Applications are available for protocol management, transgenic breeding, capacity planning, task management, accounting, facility management, and vet records. User defined templates accommodate collection of specific data for your institution. A Data Mart allows reporting and integration. PRIM&R thanks a-tune software, Inc. for supporting this year’s conference pens on March 19.

Huron Consulting Group 312.583.8700 | www.huronconsultinggroup.comTables: 12 and 13At Huron, we help our clients create the best animal care and use programs. Huron is the only provider combining the industry’s leading IACUC regulatory and process experts with the #1 IACUC enterprise software solution, Click® IACUC. Working with Huron, your research organization will improve principal investigator satisfaction, strengthen compliance, and increase organizational efficiency. PRIM&R thanks Huron Consulting Group for supporting the chair massages at the Welcome Reception in the Grand Ballroom Foyer and Grand Ballroom AB on March 19 from 5:15 to 6:30 PM.

TOPAZ Technologies, LLC 512.249.8080 | www.topazti.comTables: 14 and 15TOPAZ Technologies, LLC provides animal and clinical research software solutions for the medical research industry. With more than 35 years in the industry, TOPAZ is an established leader in delivering software-based solutions for complex regulatory environments. PRIM&R thanks TOPAZ Technologies, LLC for supporting the morning coffee break in the Grand Ballroom Foyer on March 19 from 10:15 to10:45 AM.

Bronze Supporters

Key Solutions, Inc.510.456.4500 | www.keyusa.com Tables: 7 and 8Key Solutions, Inc. is the leader in providing integrated, comprehensive software products and services to universities, hospitals, pharmaceutical companies, biotech firms, government facilities, and independent institutes worldwide. Our software solutions streamline and automate research administration and compliance processes, grants management, and conflict of interest management for our customers. Founded and based in Silicon Valley, Key Solutions continuously strives to advance discovery as an effective partner to the life science and research communities. PRIM&R thanks Key Solutions, Inc., for supporting the Common Ground Networking Lunch on March 19 from 12:15 to 1:30 PM.

Pfizer Inc: Working Together for a Healthier World®

212.733.2323 | www.pfizer.com At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety, and value in the discovery, development, and manufacture of health care products. Our global portfolio includes medicines and vaccines, as well as many of the world’s best-known consumer healthcare products. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments, and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world’s premier innovative biopharmaceutical companies, we collaborate with healthcare providers, governments and local communities to support and expand access to reliable, affordable healthcare around the world. For more than 150 years, Pfizer has worked to make a difference for all who rely on us. PRIM&R thanks Pfizer for supporting this year’s Institutional Capacity Building Scholarship Program. More information can be found on page 8.

Gold Supporters

Supporters & Exhibitors


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Exhibitors

AAALAC International 301.696.9626 | www.aaalac.orgTable: 18AAALAC International promotes the humane treatment of animals in science, research, and education through voluntary assessment, accreditation, and education programs. More than 900 institutions in 40 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use.

AALAS 901.754.8620 | www.aalas.orgTable: 17AALAS offers resources and services for the IACUC community including the AALAS Learning Library (www.aalaslearninglibrary.org) with the most comprehensive offering of online courses (more than 190) specific to the care and use of laboratory animals. IACUC Central (www.aalas.org/IACUC) is an information resource for IACUCs everywhere.

The BeFreegle Foundation 845.656.6235 | www.befreeglefoundation.orgTable: 16The BeFreegle Foundation is a unique nonprofit organization dedicated to providing sanctuary and rehabilitation to dogs that are retiring from research. The BeFreegle Foundation is committed to helping former research dogs become beloved companion animals through fostering each dog in a home environment until they are ready to be adopted. BeFreegle Foundation offers education, outreach, and foster and adoption of these dogs through both the private and public sectors via fundraising, merchandising, and participation in public events.

The Collaborative Institutional Training Initiative (CITI) Program at the University of Miami 305.243.7970 | www.citiprogram.orgTable: 4The CITI Program is a provider of web-based research ethics and compliance education. Our materials cover regulatory and ethical considerations for animal care and use, biosafety and biosecurity, conflicts of interest, export control, good clinical practice, good laboratory practice, human subjects research, information privacy and security, and responsible conduct of research.

CPIA® Program617.423.4112 | www.primr.org/certification/cpiaTable: 20The purpose of CPIA certification is to improve the quality of animal care and use programs nationwide by promoting ethical practices and advanced knowledge of IACUC administration. The CPIA credential constitutes formal recognition of an IACUC professional’s broad knowledge of IACUC functions and expertise about animal care and use programs.

iMedRIS Data Corporation909.798.9100 | www.imedris.comTable: 6iRIS, by iMedRIS Data Corporation, is an integrated research information software, offering applications such as IACUC and Assistant-Animal Facility Software (ARC). The IACUC software leads the way for inclusive animal trail reporting. ARC Assistant manages and maintains animal ordering, processing, breeding, per diem, and cage censuses. IACUC and ARC together enable researchers to manage their entire IACUC protocol cycle. iRIS also offers grants management, conflicts of interest, IRB management, and data collection.


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InfoEd Global800.727.6427 | www.infoedglobal.comTable: 5InfoEd Global would like to welcome you to PRIM&R’s 2015 IACUC Conference. There are many new and exciting things happening in the world around us in eRA. We supply world-class Enterprise Software to manage research electronically from cradle to grave. We hope to get the chance to meet all of you; please stop by our table during the conference.

IRBNet, A WIRB-Copernicus Group Company617.758.4202 | www.irbnet.orgTable: 1IRBNet is the leading compliance and research oversight solution for institutions. Founded in 2001 with an NIH Enhancement Grant, IRBNet supports more than 2,600 research sites and review boards and more than 160,000 research professionals in the successful, efficient, and integrated management of research involving humans, animals, and recombinant DNA.

Lovelace Respiratory Research Institute505.348.9400 | www.lrri.orgTable: 2Lovelace Respiratory Research Institute, a pre-clinical research institute with more than 60 years’ experience, is a leading provider in software solutions. The Animal Management Systems has been developed in a real work, pre-clinical environment focusing on compliance and operational efficiencies to better service the science.

NTM, Inc.888.eSirius | www.ntmcs.com Table: 3Headquartered in the Silicon Valley region of California, NTM, Inc. has been developing and marketing IACUC and research facility software solutions since 1995. 2013 marked the release of the latest version, eSirius3G, which includes Veterinary Care Management, Real-Time Animal Inventory Management, and IBC applications.

Questx800.558.5913 | www.questxsolutions.comTable: 11Questx delivers a comprehensive research management software that enables users to maximize resource efficacy and potential while maintaining facility best practices and adherence to industry protocols. Questx provides professional products and services tailored to the unique needs of the vivarium, and presents tools and support essential to reach your goals.

USDA, APHIS, Animal Care301.851.3751 | www.aphis.usda.govTable: 19USDA Animal Care is responsible for upholding and enforcing the AWA. The AWA and its associated regulations require that federally established standards of care and treatment be provided for certain warm-blooded animals bred for commercial sale, used in research, transported commercially, or exhibited to the public.



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Board of Directors

Officers

Alexander M. CapronChair

University of Southern California

Walter L. StrausTreasurer

Merck & Co., Inc.

Susan S. FishSecretary

Boston University

Elisa A. HurleyPRIM&R Ex officio

Barbara StanleyColumbia University

Susan Z. KornetskyVice Chair

Boston Children’s Hospital

Members

P. Pearl O’RourkePartners HealthCare

Ada Sue SelwitzUniversity of Kentucky

A. Cornelius BakerOffice of the US

Global AIDS Coordinator

David A. Borasky, Jr.Copernicus Group IRB

Joseph J. ByrneTufts University

Emeritus

Robert J. LevineYale University

Karen M. HansenFred Hutchinson Cancer

Research Center

Christine GradyNIH

Serves in Personal Capacity

Bruce G. GordonUniversity of Nebraska

Medical Center

Christian E. NewcomerAAALAC International

Hugh H. TilsonUniversity of North

Carolina at Chapel Hill

Jeremy SugarmanThe Johns Hopkins

University

Cynthia A. GómezSan Francisco State

University

Barbara E. BiererBrigham and Women’s Hospital;

Harvard Medical School

Heather H. PierceAssociation of American

Medical Colleges

David H. StraussColumbia University

Moira A. KeaneUniversity of Minnesota

Retired

Tanise L. JacksonFlorida Agricultural andMechanical University


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Staff

Sarvenaz AsasyConference

Assistant

Avery AvrakotosEducation and Policy Manager

Joanna CardinalAssistant Director for Membership and IT

Operations

Mariellen DiemandAssociate Director for Conferences

Mason DrastalRegistration and

Operations Assistant

Anne MeadeSenior Manager for Website and

Social Media

Alysa PerryMeeting Planner

Elisa A. HurleyExecutive Director

Jen Levine-FriedStaff Accountant

Meredith ElkinsDirector of Marketing and

Communications

Megan FrameMembership Manager

Caroline SlymonExecutive Coordinator

Marley ThrasherDirector of Education

and Professional Development

Maeve LuthinProfessional Development

Manager

Kimberly Hensle LowranceManaging Director

Alexandra ShlimovichWebinar and

Publications Specialist

Jose Pablo Salas RojasProgram Coordinator



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PRIM&R would like to thank our member volunteers who serve on our standing committees. In doing so, they generously share their time and energy with PRIM&R to the greater good of the research ethics community. Their contributions are critical to fulfilling our mission of advancing the highest ethical standards in the conduct of research through education, membership services, professional certification, public policy initiatives, and community building.

EDUCATION COMMITTEEThe Education Committee sets broad educational goals to further PRIM&R’s mission and uphold its core values through: (1) determining and prioritizing the educational needs of its membership; (2) monitoring trends in the field to recommend and develop appropriate educational opportunities; and (3) evaluating educational activities to determine whether the educational goals are being met.

Ada Sue Selwitz, MA (Chair)Emily E. Anderson, PhD, MPHRebecca D. Armstrong, DVM, PhDM. Jeremy Corsmo, MPH, CIPJonathan M. Green, MDKaren M. HansenSusan Z. Kornetsky, MPHRobert J. Levine, MDChristian E. Newcomer, VMD, MS, DACLAM

KNOWLEDGE CENTER ADVISORY GROUPThe Knowledge Center Advisory Group is charged with guiding the development of the Knowledge Center (www.primr.org/knowledgecenter). This group contributes to goal setting and strategic planning for the site. Advisory group members also participate in the development of new resources. Through its work, the group is an integral part of PRIM&R’s continued efforts to provide human subjects protections and animal care and use professionals with the resources they need to do their jobs effectively and efficiently.

Lois Brako, PhD (Chair)Hila Berger, MPH, CIPMelissa A. Epstein, PhD, CIPAmy Neuman, MPHKaarkuzhali Babu Krishnamurthy, MDMichael Leary, MA, CIPGina Prochilo-Cawston, MS, CPIA, PMPLauren Solberg, JD, MTSMatt Zembrzuski, MEd

MEMBERSHIP COMMITTEEPRIM&R’s Membership Committee works to strengthen the membership community by improving the reach of member benefits and volunteer opportunities. The Membership Committee reviews applications for PRIM&R’s Regional Connections Program, conduct outreach to welcome new members to PRIM&R’s community, and evaluate membership initiatives. These efforts, as well as their thoughtful group discussions, allow the Membership Committee to reach broader audiences and cultivate new leadership from within the PRIM&R community.

Susan S. Fish, PharmD, MPH (Co-Chair)David G. Cannon, CPIA (Co-Chair)Carol Bienstock, CIP Karen M. HansenJoy Jurnack, RN, CCRC, CIPGreg E. Manship, D.Bioethics, MDiv, CIPMaribel MartinezKelly O’Keefe, MPHLaWanda Holland Thompson, PhDSteven Ziemba, PhD, FACHE, CIP, CCRC

DIVERSITY ADVISORY GROUPThe Diversity Advisory Group’s goal is to examine the issue of diversity as it pertains to PRIM&R’s membership. Specifically, the Diversity Advisory Group makes recommendations to the staff and the PRIM&R Board of Directors regarding strategies and/or activities designed to ensure that we are maximizing our outreach to diverse populations (including diversity of gender, age, ethnicity, race, geography, professional position, and institutional affiliation) and that PRIM&R is generally fostering an environment where different communities, professions, and ideas can flourish.

Eric Mah, MHS, CIP (Chair)Eric Allen, CIP, CPIADonna H. Eaton, RN, MSN, MHAMelissa A. Epstein, PhD, CIPSusan S. Fish, PharmD, MPH William Freeman, MD, MPH, CIPDorotha Love Hall, PhD, MPA, CIPDonna Matthews Jarrell, DVM, DACLAMNatalie L. Mays, BA, LATG, CPIARoberto L. Veloso, JD

Thank You to Our 2015 Committee Members


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Mr. Spira was a frequent participant at PRIM&R’s meetings, active both at the podium and in dialogue with the scientific community on issues related to animal welfare. He emphasized the necessity of working across ideological lines and communicating with individuals and organizations that hold opposing points of view. In a 1997 film about his life, Mr. Spira stated: “If there are going to be alternatives to the use of animals, it’s the people in the research community who will be developing alternatives. If you’re going to get the regulatory agencies to change their requirements, it’s going to be animal researchers who are the ones who are going to do it... these are the folks that you need if you’re going to be serious about change…”

In this spirit, and in Mr. Spira’s memory, PRIM&R is proud to present the 14th annual Henry Spira Memorial Lecture:

Primate Social IntelligenceDelivered by Frans B. M. de Waal, PhD Friday, March 20, 8:15-9:00 AM Grand Ballroom AB

Frans B. M. de Waal, PhD, is a Dutch/American biologist and primatologist known for his work on the behavior and social intelligence of primates. He is the Charles Howard Candler Professor of Primate Behavior in the psychology department of Emory University, and the director of the Living Links Center at the Yerkes National Primate Center in Atlanta, GA. His first book, Chimpanzee Politics: Power and Sex Among Apes (1982), compared the “schmoozing and scheming” of chimpanzees involved in power struggles with that of human politicians.

Dr. de Waal’s scientific work has been published in hundreds of technical articles in journals such as Science, Nature, and Scientific American, as well as publications specialized in animal behavior. His popular books have been translated into many languages, making him one of the world’s most visible primatologists.

His most recent books are The Age of Empathy (2009) and The Bonobo and the Atheist: In Search of Humanism Among the Primates (2013). Dr. de Waal has been elected to the National Academy of Sciences, the American Academy of Arts and Sciences, and the Royal Dutch Academy of Sciences. In 2007, he was selected by Time as one of “The World’s 100 Most Influential People Today” and, in 2011, was listed by Discover among the “47 (All-Time) Great Minds of Science.”

Through his work, Dr. de Waal challenges our understanding of human morality and raises questions about what constitutes ethical research with chimpanzees and other primates. This, along with his dedication to communicating the importance of research to the public, makes him an appropriate and fitting choice to present the Henry Spira Memorial Lecture.

Dr. de Waal will read from and sign his book titled The Bonobo and the Atheist: In Search of Humanism Among the Primates at the Research Ethics Book Group Lunch on Friday, March 20, 12:15-1:15 PM in Grand Ballroom CD. Please note, pre-registration for this special lunch was required; if you did not register but would like to attend, please visit the Help Desk.

Since his death in 1998, Henry Spira, a passionate and effective social justice advocate, animal rights activist, and an uncommonly wise and grounded individual, has been recognized at PRIM&R’s IACUC Conference through the Henry Spira Memorial Lecture. PRIM&R hosts this lecture both to honor his memory and to commemorate his ability to bring together the scientific and animal rights communities.

Henry Spira Memorial Lecture


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Tuesday, March 17 • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • 12:00-5:00 PM Essentials of IACUC Administration Harbor Ballroom II

Wednesday, March 18 • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • 8:00 AM-5:00 PM Essentials of IACUC Administration Harbor Ballroom II

8:00 AM-5:00 PM IACUC 101TM: “The Basics” Grand Ballroom AB

5:00-6:30 PM Pre-Conference Programs Networking Reception Grand Ballroom Foyer

Thursday, March 19 • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • 7:00-8:00 AM Continental Breakfast to Welcome First-Time Attendees (pre-registration required) Grand Ballroom CD


8:15-9:00 AM Keynote Address: Darin S. Carroll Grand Ballroom AB

9:00-10:15 AM Panel I: Structuring Your IACUC for Efficiency and to Facilitate Research Grand Ballroom AB


10:45 AM-12:00 PM Didactic Sessions and Workshops Series A See schedule for room locations

12:15-1:30 PM Common Ground Networking Lunch Galleria Hall

1:45-2:30 PM Keynote Address: David K. Meyerholz Grand Ballroom AB

2:30-3:45 PM Panel II: Studies of Animals When They Are the Targeted Beneficiaries Grand Ballroom AB


4:00-5:15 PM Didactic Sessions and Workshops Series B See schedule for room locations

5:15-6:30 PM 2015 IACUC Conference Welcome Reception Grand Ballroom AB & Grand Ballroom Foyer

Friday, March 20 • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •7:00-8:00 AM CPIA® Networking Continental Breakfast (pre-registration required) Grand Ballroom CD


8:15-9:00 AM Henry Spira Memorial Lecture: Frans B. M. de Waal Grand Ballroom AB

9:00-10:15 AM Panel III: Fallout from FOIA Grand Ballroom AB


10:45 AM-12:00 PM Didactic Sessions and Workshops Series C See schedule for room locations

12:15-1:15 PM Lunch Galleria Hall

12:15-1:15 PM Research Ethics Book Group Lunch and Book Signing with Author and

Henry Spira Memorial Lecturer Frans B. M. de Waal, PhD (pre-registration required) Grand Ballroom CD

1:30-2:45 PM Panel IV: Virtual IACUC: This Meeting Is in Session! Grand Ballroom AB


3:00-4:15 PM Didactic Sessions and Workshops Series D See schedule for room locations

4:15-4:30 PM Break

4:30-5:45 PM 2015 IACUC Conference Town Hall Meeting Grand Ballroom AB

5:45-6:45 PM Closing Reception Grand Ballroom Foyer

Schedule at a GlanceP

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