+ All Categories
Home > Documents > 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI...

2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI...

Date post: 19-Jul-2020
Category:
Upload: others
View: 3 times
Download: 0 times
Share this document with a friend
58
2016 APCBEES TAIPEI CONFERENCE - 1 - 2016 APCBEES TAIPEI CONFERENCE ABSTRACT November 12-14, 2016 Taipei, Taiwan Sponsored and Published by Indexed by www.cbees.org
Transcript
Page 1: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 1 -

2016 APCBEES TAIPEI CONFERENCE

ABSTRACT

November 12-14, 2016

Taipei, Taiwan

Sponsored and Published by

Indexed by

www.cbees.org

Page 2: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 2 -

Table of Contents

2016 APCBEES Taipei Conference Introductions 5

Presentation Instructions 7

Keynote Speaker Introductions 8

Brief Schedule for Conference 16

Detailed Schedule for Conference 17

Session 1

E0002: Industrialization of Lipid Nanoparticles: From Lab-Scale to Large-Scale Production Line

Caibiao Hu, Airui Qian and Qiang Xia

18

E0023: The Novel Potential Therapeutic Target for Liver Fibrosis - Intracellular Oxidative Stress

Sensor

Jing Liu and Pingsheng Chen

19

E0024: Establishment of a Murine Model of Chronic Cyclosporin a Nephrotoxicity via Gavage

without Low-Sodium Diet

Zhengyuan Cheng and Jing Liu

21

B1001: Selection of Oleaginous Yeasts with Lipid Accumulation by the Measurement of Sudan

Black B for Benefits of Biodiesel

Kusumawadee Thancharoen, Auttaporn Malasri, Walailak Leamsingkorn and Patchareeporn

Boonyalit

22

B3001: Mass Cultivation and Antifungal Activity of Microbial Agents for Farming

Kong-Min Kim, Ki Moon Bong, Jae-Hong Yoo, In Chul Park and Pyoung Il Kim

23

B3002: Statistical Optimization of Nutritional Medium Constituents for Carotenoid Production

by Rhodobacter Sphaeroides PS-24

Ki Moon Bong, Kong-Min Kim, Jae-Hong Yoo, In Chul Park and Pyoung Il Kim

24

Session 2

E0005: Algorithm for Segmentation and Reduction of Fractured Bones in Computer-Aided

Preoperative Surgery

Irwansyah Idram, Jiing-Yih Lai, Terence Essomba and Pei-Yuan Lee

25

E0012: A Novel Framework for Repeated Measurements in Diffusion Tensor Imaging

Mohammad Alipoor, Irene Y.H. Gu, Andrew Mehnert, Göran Starck and Stephan E. Maier

26

E0017: Tactile Sensor for Cardiovascular Catheters

Chao-Hsien Huang, Cheng-Hung Shih and Nai-Jun An

27

Page 3: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 3 -

E0019: Development of a Swordsmanship Machine Enabling the Inner and Outer Muscles to Be

Safely Trained While Having Fun

Kiyoshi Hoshino and Chuanhan Cheng

28

E0020: Hand Motion Capture for Medical Usage

Kiyoshi Hoshino, Sota Sugimura, Motomasa Tomida, Naoki Igo, Isao Kawano and Masahiko

Sumitan

29

E0021: Measurement of Rotational Eye Movement with Blue Light Irradiation

Kiyoshi Hoshino, Nayuta Ono, Motomasa Tomida and Naoki Igo

30

E0022: Measurement of Rotational Eye Movement with Blue Light Irradiation

Josimar Edinson Chire Saire and Yvan Tupac

31

Session 3

C0002: Prediction of the Vapor–Liquid Equilibrium of Formaldehyde–Water–Trioxane Ternary

System by the Conductor-like Screening Model for Real Solvents

Huihong Liu, Zhenmin Bai, Yansheng Liu, XuqiangGuo and Yu’eFu

32

C0004: Prediction of Vapor-Liquid Equilibrium Properties for the Mixture of Propylene+Propane

from the Combined Use of Peng-Robinson Equation of State and Cosmo-Rs Model

Xinyun Pu, Lehuan Wu and Yansheng Liu

33

C0005: Solvent Screening for Cyclopentane Purification Based on COSMO-RS

Lehuan Wu, Xinyun Pu and Yansheng Liu

34

C0007: Schiff Base Transition Metal Complexes for ROP of L-Lactide

S Mantri, H. C. Pradhan, T Maharana and Alekha Kumar Sutar

35

C0008: Polymer Supported Schiff Base Iron Complex for Epoxidation of Trans-Stilbene

N. Natha, H. C. Pradhanb, Tungabidya Maharana and A. K. Sutar

36

Poster Session

B0017: Classification of Cardiac Arrhythmias Using Ensemble Classifiers with Reduced Features

Zeynep Beyza Zileli and Niyazi Kilic

37

B0018: Design and Implementation of Software Based Audiometer System

Mehmet Cem Catalbas and Hasan Guler

38

E0001: Fluctuation Characteristics of NO2 Pollution over Yangtze River Delta during the Period

of Global Financial Crisis

Yin Du and Zhiqing Xie

39

E0003: Analysis of the FGOALS Simulation on East Asian Westerly Jet in CMIP5 during the

Meiyu Season

40

Page 4: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 4 -

Yin Du and Zhiqing Xie

E0007: Study on Ratcheting Behavior of Trabecular Bone with and without Marrow under Cyclic

Compression

Chao-lei Wei, Li-lan Gao and Chun-qiu Zhang

41

E0009: Mechanical Behavior of Articular Cartilage Soaked in Physiological Saline under Cyclic

Compressive Loading

Dong-dong Liu, Li-lan Gao and Xiao-yi Qin

42

E0010: Research on the Factors of Colonoscopy Screening Compliance in High-Risk Colorectal

Cancer Groups

MA Hong-mei and LU Jian-hong

43

E0011: Biocompatibility Evaluation of Organic Acid-Decellularized Based Methods on Porcine

Corneal Scaffold

Hung-Jun Lin, Ting-Wei Li, Ping-Lun Jiang, Chon-Ho Yen, Ching-Fu Tu, Ming-Thau Sheu,

Yi-You Huang and Der-Zen Liu

44

E0013: Numerical Simulation of the Adenoidectomy Preoperative and Postoperative Upper

Airway in Children with OSAHS

Gang Wang, Chi Yu and Jing Zhang

45

E0014: Analysis of Methicillin-resistant Staphylococcus Aureus Using Apriori, DBSCAN, and

K-means Algorithms

Min Young Lee and Taeseon Yoon

46

C3002: Development of Superhydrophobic Silk Fabrics using Alkaline Hydrolysis

Sujin Lee, Suhyun Lee and Chung Hee Park

47

C3003: Fabrication of Single-faced Superhydrophobic Polyester Fabric via Alkaline Hydrolysis

and Blade Coating

Kirim Kim, Seon Young Youn and Chung Hee Park

48

C3004: Superhydrophobicity of Nanostructured Conductive Fabric Treated with Cf4 Plasma and

Water Immersion Treatment

Sohyun Park, Hey-sang Kim, Kyungha Baik and Chung Hee Park

49

Conference Venue 50

APCBEES Forthcoming Conferences 51

Note 54

Feedback Information 57

Page 5: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 5 -

2016 APCBEES Taipei Conference

Introductions

Welcome to CBEES 2016 conferences in Taipei, Taiwan. The objective of the Taipei conferences is to provide a platform for researchers, engineers, academicians as well as industrial professionals from all over the world to present their research results and development activities in Chemical Science and Engineering, Agriculture and Biotechnology, Biomedical and Bioinformatics Engineering.

2016 5th International Conference on Chemical Science and Engineering (ICCSE 2016)

Paper publishing and index: ICCSE 2016 papers will be published the following journal:

International Journal of Chemical Engineering and Applications (IJCEA,

ISSN: 2010-0221) and will be included in the Engineering & Technology

Digital Library, and indexed by WorldCat, Google Scholar, Cross ref,

ProQuest.

Conference website and email: http://www.iccse.org/; [email protected].

2016 4th International Conference on Agriculture and Biotechnology (ICABT 2016)

Paper publishing and index: ICABT 2016 papers will be published in one of the following

journals:

Journal of Advanced Agricultural Technologies (JOAAT, ISSN:

2301-3737), and will be included in the Engineering & Technology Digital

Library, and indexed by Ulrich's Periodicals Directory, Google Scholar,

Engineering & Technology Digital Library, Crossref and Electronic

Journals Digital Library.

International Journal of Life Sciences Biotechnology and Pharma

Research (IJLBPR, ISSN:2250-3137), and will be included in the

Engineering & Technology Digital Library, and indexed by Embase (Under

elsevier), ProQuest, Google Scholar, Chemical Abstracts Services (CAS),

Indian Science, ICMJE(International Committee Medical Journal

Editors), HINARI(World Health Organization), and NYU(Health Sciences

Library).

Conference website and email: http://www.icabt.org/;[email protected].

Page 6: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 6 -

2016 3rd International Conference on Biomedical and Bioinformatics Engineering

(ICBBE 2016)

Paper publishing and index: ICBBE 2016 papers will be published in the following journal:

International Conference Proceedings Series by ACM, which will be archived in the ACM

Digital Library, and indexed by Ei Compendex and Scopus and submitted to be reviewed by

Thomson Reuters Conference Proceedings Citation Index (ISI Web of Science).

Conference website and email: http://www.icbbe.com/;[email protected].

Page 7: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 7 -

Presentation Instructions

Instructions for Oral Presentations

Devices Provided by the Conference Organizer:

Laptop Computer (MS Windows Operating System with MS PowerPoint and Adobe Acrobat

Reader)

Digital Projectors and Screen

Laser Sticks

Materials Provided by the Presenters:

PowerPoint or PDF Files (Files should be copied to the Conference laptop at the beginning of

each Session.)

Duration of each Presentation (Tentatively):

Regular Oral Presentation: about 12 Minutes of Presentation and 3 Minutes of Question and

Answer

Keynote Speech: about 25 Minutes of Presentation and 5 Minutes of Question and Answer

Instructions for Poster Presentation

Materials Provided by the Conference Organizer:

The place to put poster

Materials Provided by the Presenters:

Home-made Posters

Maximum poster size is A1

Load Capacity: Holds up to 0.5 kg

Best Presentation Award One Best Oral Presentation will be selected from each presentation session, and the

Certificate for Best Oral Presentation will be awarded at the end of each session on November

13, 2016.

Dress code Please wear formal clothes or national representative of clothing.

Page 8: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 8 -

Keynote Speaker Introductions

Keynote Speaker I

Prof. David Zhang

Hong Kong Polytechnic University, Hong Kong

Prof. David Zhang graduated in Computer Science from Peking University. He received his MSc in 1982

and his PhD in 1985 in Computer Science from the Harbin Institute of Technology (HIT), respectively.

From 1986 to 1988 he was a Postdoctoral Fellow at Tsinghua University and then an Associate Professor at

the Academia Sinica, Beijing. In 1994 he received his second PhD in Electrical and Computer Engineering

from the University of Waterloo, Ontario, Canada. He is a Chair Professor since 2005 at the Hong Kong

Polytechnic University where he is the Founding Director of the Biometrics Research Centre (UGC/CRC)

supported by the Hong Kong SAR Government in 1998. He also serves as Visiting Chair Professor in

Tsinghua University, and Adjunct Professor in Peking University, Shanghai Jiao Tong University, HIT, and

the University of Waterloo. He is Founder and Editor-in-Chief, International Journal of Image and Graphics

(IJIG); Founder and and Series Editor, Springer International Series on Biometrics (KISB); Organizer, the

1st International Conference on Biometrics Authentication (ICBA); Associate Editor of more than ten

international journals including IEEE Transactions and so on. So far, he has published over 10 monographs,

400 journal papers and 35 patents from USA/Japan/HK/China. According to Google Scholar, his papers

have got over 35,000 citations and H-index is 86. He was listed as a Highly Cited Researcher in

Engineering by Thomson Reuters in 2014 and in 2015, respectively. Professor Zhang is a Croucher Senior

Research Fellow, Distinguished Speaker of the IEEE Computer Society, and a Fellow of both IEEE and

IAPR.

Page 9: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 9 -

Topic: “Medical Biometrics”

Abstract: As one of the most powerful and reliable means of personal authentication, biometrics has been

an area of particular interest. In this talk, we will explore how biometrics technology could be also applied

to medical applications. By learning from the biometrics definition, medical biometrics could be

implemented by measuring different human being’s surface information, extracting all possible features as

their representations and making a correct final decision. As a case study, Traditional Chinese Medicine

(TCM) diagnosis methods, including looking/smelling/touching, are developed by using of medical

biometrics.

Page 10: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 10 -

Keynote Speaker II

Assoc. Prof. KUO-YUAN HWA

National Taipei University of Technology, Taiwan

Dr. Kuo-Yuan Hwa is an associate professor and the director of the Center for Biomedical Industries at the

National Taipei University of Technology. Dr. Hwagraduated and received her PhD from the School of

Medicine, the Johns Hopkins University. She is the president of the Medical Association for Indigenous

Peoples of Taiwan (MAIPT). Dr. Hwa’s scientific interests are: 1) nanotechnology and biosensor, 2) new

drug discovery for human diseases by proteomics and genomics approaches and 3) glycobiology, especially

on enzymes kinetics. She has published 85 conference and journal articles and 10 patents. She has served in

many national and international committees. Dr. Hwa has been invited as a speaker for many academic

research institutes and universities in China, Korea, Japan and USA. She has been invited as a reviewer, a

judge and an editor for international meetings and journals. In addition, one of her currently works is on

developing culturally inclusive health science educational program, with both indigenous and western

science knowledge for indigenous children.

Page 11: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 11 -

Topic: “Studies on Anticancer Activities of Quinoline Derivatives by Bioinformatics

Analysis”

Abstract: Chemotherapy has been commonly used for cancer treatment although many advanced

approaches have been used such as particle therapy, antibody therapy, and immune/cell therapy. However,

the newly advanced approaches require large investment for development and high cost to the patient.

The best outcome is still from chemotherapy, especially with the target therapy. By regulation or

interfering into specific pathways controlling cancer cell progression, the molecular targeted drugs may

dramatically improve the therapeutic effect. A series of quinoline derivatives with the fluoride side chain

had the excellent effect in inhibiting human breast cancer cells. The selection criteria was set for

maximum anti-tumor activity and minimum adverse effect to the normal non-transformed NIH-3T3 Cell.

We have use DNA-microarray and bioinformatics tools and database to analysis the anti-cancer mechanism

of the compounds. The mechanism studies show that the novel quanoline compounds indicated that the

anti-tumor activity was due to induction of cell death. The targeted pathway was identified as the

JAK-STAT pathway. We had also validated the analysis by performed Western and cellular assay on

apoptosis and on expression of selected gene expression.

Page 12: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 12 -

Keynote Speaker III

Assoc. Prof. Chuan-Hsiung Chang

National Yang Ming University (NYMU), Taiwan

Dr. Chuan-Hsiung Chang received his PhD in Molecular Biology from the University of Southern

California (USC) and did postdoctoral work on cancer genomics at the Cancer Research Institute,

University of California, San Francisco (UCSF). He then worked as a Research Fellow and the Department

Head of the Genomics Department at Industrial Technology Research Institute (ITRI), Taiwan. Dr. Chang is

currently an Associate Professor of the Center for Systems and Synthetic Biology and Institute of

Biomedical Informatics at the National Yang Ming University (NYMU), Taiwan. His multidisciplinary

research team is interested in applying both forward and reverse engineering approaches to characterize

whole genome blueprints and investigating their use in genome design and engineering. They have

developed comprehensive bioinformatics pipeline for computer aided analysis and design of whole

genomes to capture and to understand the underlying mechanisms behind multi-level and multi-scale

high-throughput experimental data of various organisms.

Professional Honors

n Zoller-Landfear Breast Cancer Scholar Award

n American Association for Cancer Research (AACR) Young Investigator Award

n International Synthetic Biology Competition:

iGEM Asia Advisory Board Member

iGEM Synthetic Biology Competition - Asia and World Championship Judge

Gold Medal and Grand Finalist Awards

Page 13: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 13 -

Topic: “To be added”

Page 14: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 14 -

Keynote Speaker IV

Assoc. Prof. Chi-wai KAN

Institute of Textiles and Clothing,

The Hong Kong Polytechnic University

Hung Hom, Kowloon, Hong Kong

Dr. Kan graduated from Hong Kong Polytechnic with a BSc in Textile Chemistry. He gained his PhD

degree from the Hong Kong Polytechnic University. He had worked in private and public sectors in the

area of textile evaluation and safety and health management for more than five years before joining the

Institute. His main duties in the Institute are in the area of teaching colouration and finishing. Dr. Kan's

research interests are also in the area of colouration and finishing.

Dr. Kan holds the professional qualification of Chartered Colourist, Chartered Textile Technologist and

Chartered Safety and Health Practitioner; also Fellowship of the Society of Dyers and Colourists and

Textile Institute, U.K. In addition, Dr. Kan is a member of Royal Society of Chemistry, Institution of

Occupational Safety and Health and Hong Kong Institution of Textile and Apparel.

Page 15: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 15 -

Topic: “Solvent-assisted Dyeing of Cotton with Reactive Dyes”

Abstract: The dyeability of cotton fabrics with reactive dye, in non-aqueous solvent medium of heptane and

octane was investigated using reverse-micellar approach comprising of poly(ethylene glycol)-based

surfactant. The reactive dye was satisfactorily encapsulated in the reverse micelle under the optimised

process parameters as measured by the colour yield. Dyeability of cotton fibre with reactive dye from the

reverse micellar solution was improved even in the absence of electrolytes. Optimisation of dyeing and

fixation process could be achieved in a one-bath reverse-micelle solution. Experimental results revealed

that dyeability in the alkane-assisted dyeing process is better than that in conventional water-based dyeing

without incorporation of electrolytes. The scanning electron microscopic (SEM) images showed no obvious

surface damage from heptane or octane but some microfibrils were noticed.

Page 16: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 16 -

Brief Schedule for Conference

Day 1

November 12, 2016 (Saturday)

Venue: 卡博廰 (Room No.203)

Arrival Registration, Committee Meeting & Free Talk

Arrival Registration

Arrival Registration 10:00~16:00

Committee Meeting & Free Talk 14:00~16:00

Day 2

November 13, 2016 (Sunday) 08:30~17:30

Venue: 西特廰 (Room No.204)

Keynote Speeches & Conference Presentations

Morning Conference

Opening Remarks 08:30~08:35

Keynote Speech I 08:35~09:05

(Prof. David Zhang, Hong Kong Polytechnic University, Hong Kong)

Topic: “Medical Biometrics”

Keynote Speech II 09:05~09:35

(Assoc. Prof. KUO-YUAN HWA, National Taipei University of Technology, Taiwan)

Topic: “Studies on Anticancer Activities of Quinoline Derivatives by Bioinformatics Analysis”

Keynote Speech III 09:35~10:05

(Assoc. Prof. Chuan-Hsiung Chang, National Yang Ming University (NYMU), Taiwan)

“To be added”

Coffee Break & Photo Taking 10:05~10:30

Keynote Speech IV 10:30~11:00

(Assoc. Prof. Chi-wai KAN, Hong Kong Polytechnic University, Hong Kong)

Topic: “Solvent-assisted Dyeing of Cotton with Reactive Dyes”

Session 1: 11:00~12:30

6 presentations-Topic: “Agriculture and Biotechnology”

Lunch 12:30~13:30 Venue: Restaurant

Afternoon Conference

Session 2: 13:30~15:15

7 presentations-Topic: “Bioinformatics and Computational Biology”

Coffee Break 15:15~15:30

Session 3: 15:30~16:45

5 presentations-Topic: “Chemical Engineering and Technology”

Poster Session: 8:30~17:30

13 presentations

Dinner 18:00 Venue: Restaurant

Tips: Please arrive at the conference room 10 minutes before the session begins to upload PPT into the laptop.

Page 17: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 17 -

Detailed Schedule for Conference

November 12, 2016 (Saturday)

Venue: 卡博廰 (Room No.203)

10:00-16:00 Arrival Registration

14:00-16:00 Committee Meeting & Free Talk

Note:(1) The registration can also be done at any time during the conference.

(2) The organizer doesn’t provide accommodation, and we suggest you make an early reservation.

(3) One best oral presentation will be selected from each oral presentation session, and the Certificate

for Best Oral Presentation will be awarded at the end of each session on November 13, 2016.

Morning, November 13, 2016 (Sunday)

Venue: 西特廰 (Room No.204)

08:30~08:35

Opening Remarks

Assoc. Prof. KUO-YUAN HWA

Incheon National University, Republic of Korea

National Taipei University of Technology, Taiwan

08:35~09:05

Keynote Speech I

Prof. David Zhang

Hong Kong Polytechnic University, Hong Kong

Topic: “Medical Biometrics”

09:05~09:35

Keynote Speech II

Assoc. Prof. KUO-YUAN HWA

National Taipei University of Technology, Taiwan

Topic: “Studies on Anticancer Activities of Quinoline Derivatives by

Bioinformatics Analysis”

09:35~10:05

Keynote Speech III

Assoc. Prof. Chuan-Hsiung Chang

National Yang Ming University (NYMU), Taiwan

Topic: “To be added”

10:05~10:30

Coffee Break & Photo Taking

10:30~11:00

Keynote Speech IV

Assoc. Prof. Chi-wai KAN

Hong Kong Polytechnic University, Hong Kong

Topic: “Solvent-assisted Dyeing of Cotton with Reactive Dyes”

Page 18: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 18 -

Let’s move to the Sessions!

Session 1

Tips: The schedule for each presentation is for reference only. In case of missing your presentation,

we strongly suggest that you attend the whole session.

Moring, November 13, 2016 (Sunday)

Time: 11:00~12:30

Venue: 西特廰 (Room No.204)

Session 1: 6 presentations-Topic: “Agriculture and Biotechnology”

Session Chair: Assoc. Prof. KUO-YUAN HWA

E0002 Presentation 1 (11:00~11:15)

Industrialization of Lipid Nanoparticles: From Lab-Scale to Large-Scale Production Line

Caibiao Hu, Airui Qian, and Qiang Xia

Southeast University, China

Abstract—This work aimed at developing a large-scale modular production line, which

referred to coenzyme Q10 loaded-NLC as well as its continuous and scalable emulsification

and homogenization process. The production line exhibited good control over the

emulsification and homogenization process and enabled the particle size of NLC below 210

nm at a throughput of 25 kg/h (for lipid solution at a flow rate of 0.4 kg/min). Among the

several process parameters investigated, the size of the NLC was mainly influenced by the

pre-emulsification temperature, homogenization pressure and homogenization, and suitable

emulsification temperature (70 °C), homogenization pressure (600, 800 bar), homogenization

cycle (3, 4 cycles) resulted in relatively smaller particles. These results proved that coenzyme

Q10, a model active, had been successfully loaded into the NLC. Meanwhile, the large-scale

production line can be effectively applied for continuous and modular production of NLC.

The line had modern networking features-essential in the Internet age-and a modular design

that was easily modified and upgraded. In addition, the long-term stability over 6 month was

monitored at 30 ◦C and at 40 ◦C to assess a potential effect of the lab scale and large scale on

stability. All batches at room temperature and below were stable, only a negligible increase in

size was observed.

Page 19: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 19 -

Moring, November 13, 2016 (Sunday)

Time: 11:00~12:30

Venue: 西特廰 (Room No.204)

Session 1: 6 presentations-Topic: “Agriculture and Biotechnology”

Session Chair: Assoc. Prof. KUO-YUAN HWA

E0023 Presentation 2 (11:15~11:30)

The Novel Potential Therapeutic Target for Liver Fibrosis - Intracellular Oxidative Stress

Sensor

Jing Liu and Pingsheng Chen

Southeast University, China

Abstract—Background and Aim Liver fibrosis is a common pathological process resulting

from chronic liver damage, and oxidative stress is involved in this process. The intracellular

oxidative stress sensor Keap1 (Kelch-like ECH-associated protein 1) negatively regulates

Nrf2 (Nuclear factor-erythroid2 p45-related factor 2) which activates cellular antioxidant

response against oxidative stress. In this article, we use the small hairpin RNA (shRNA) to

silence oxidative stress sensor with the hope to explore a novel therapeutic target for liver

fibrosis.

Methods Four pairs of Keap1shRNA (named as Plvx/GFP/puro-Keap1-1781,1894,1934,2097)

and a pair of negative control shRNA were designed, then were respectively transfected into a

mouse liver cell(AML12) in order to choose the target sequence whose expression was lower

than others by qRT-PCR. Keap1shRNA transfected cells were exposed to 1% hypoxia for

various time points up to 48 hours. Subsequently, the expression of Keap1, Nrf2, collagen

I(col1a1), collagenIII(col1a3), transforming growth factor-(TGF-1), and vascular

endothelial growth factor -A(VEGF-A), insulin-like growth factor 1 (IGF-1)were analyzed

either by Western blot or qRT-PCR.

Next, the Enzyme-linked immunosorbent assay (ELISA) was employed to determine the

COL1A1, COL1A3 levels in supernatant of transfected cells. The analysis of apoptosis were

assessed using flow cytometry and caspased 8 protein expression, the Lipid Peroxidation and

antioxidant Enzymes activity were carried out by MDA and GSH assay and the lactate

dehydrogenase (LDH) assays were performed to evaluate the potential cellular activity.

Results The target pair Keap1-1781 was selected and the rate of this gene/GAPDH expression

was 0.38±0.09, which is the lowest expression compared with the others (P<0.05). The

silencing of Keap1 gene increased Nrf2 protein and mRNA expression under hypoxic

conditions, western blot indicated that col1a1, col1a3, TGF-1, VEGF-A, IGF-1 expression

Page 20: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 20 -

decreased as well (P<0.05). ELISA also revealed the decreased col1a1, col1a3 expression in

transfected cells compared with the negative control, which is consistent with western blot

results. In addition, transfection of the Keap1shRNA displayed higher cellular activity,

antioxidant effect and reduced hypoxia-induced cell apoptosis.

Conclusion Taken together, our results indicate that silencing of Keap1 significantly

attenuated liver fibrosis progression through the decreased hepatocyte oxidative stress,

offering a new treatment perspectives for liver fibrosis.

Page 21: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 21 -

Moring, November 13, 2016 (Sunday)

Time: 11:00~12:30

Venue: 西特廰 (Room No.204)

Session 1: 6 presentations-Topic: “Agriculture and Biotechnology”

Session Chair: Assoc. Prof. KUO-YUAN HWA

E0024 Presentation 3 (11:30~11:45)

Establishment of a Murine Model of Chronic Cyclosporin a Nephrotoxicity via Gavage

without Low-Sodium Diet

Zhengyuan Cheng and Jing Liu

Southeast University, China

Abstract—Bcakground Previous studies have created a murine model of chronic cyclosporin

A(CsA) nephrotoxicity almost via the subcutaneous injection of CsA combined with a

low-sodium(0.01%Na) diet. This study aimed to establish this model by gavage

administration of CsA and furosemide in the absence of a low-sodium diet. Methods Mice

were randomized into six groups, and were administered either: 1) CsA + furosemide; 2) CsA;

3) furosemide; 4) sunflower oil; 5) distilled water; or 6) no treatment. The body weight was

recorded every 7 days and on Day 14 and Day 28, a subset of mice were sacrificed , from

which blood and kidney samples were obtained. The renal function was determined by

profiling serum albumin (ALB), creatinine (Scr), and blood urea nitrogen (BUN). The gross

morphology of kidney was observed, and micro-specimens were stained with

Hematoxylin-Eosin (H&E), Masson-trichrome (Masson), and Periodic Acid-Schiff (PAS) for

assessment of kidney pathology. Finally, kidney microsections were stained with an antibody

targeting the Vimentin protein, which was subsequently visualized. Results The kidneys of

mice administered CsA and furosemide manifested obvious signs of fibrosis, and blood

profiles indicated abnormal renal function. Various histopathological stains revealed notable

interstitial inflammatory-cell infiltration, collagen deposition, and afferent arteriolar sclerosis

relative to other treatments. Immunohistochemistry alluded to fibroblast proliferation.

Conclusions Based on the above, a murine model of CCN was established by administering

CsA to mice and furosemide over 28 days by gavage.

Page 22: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 22 -

Moring, November 13, 2016 (Sunday)

Time: 11:00~12:30

Venue: 西特廰 (Room No.204)

Session 1: 6 presentations-Topic: “Agriculture and Biotechnology”

Session Chair: Assoc. Prof. KUO-YUAN HWA

B1001 Presentation 4 (11:45~12:00)

Selection of Oleaginous Yeasts with Lipid Accumulation by the Measurement of Sudan Black

B for Benefits of Biodiesel

Kusumawadee Thancharoen, Auttaporn Malasri, Walailak Leamsingkorn and

Patchareeporn Boonyalit

Rajabhat MahaSarakham University/Department of Biology, MahaSarakham, Thailand

Abstract—Microbial lipids possess significant potential which can be explored for biodiesel

production. This study attempted to screened oleaginous yeasts and selected the strain that

accumulated the largest quantity of lipid for lipid production from glucose. Among the 24

yeast strains isolated from Canteen Wastewater, 10 oleaginous yeasts were selected by Sudan

Black B test. Sudan Black B staining revealed the presence of lipid inclusion bodies in the

cells during cultivation under nitrogen-limiting conditions. Total oleaginous strains that

accumulated quantities of lipid higher than 20% of their biomass when cultivated in glucose.

It was found that accumulated the CTWY07 highest lipid content, up to 71.59% of its

biomass (4.904 g/L lipid and 6.85 g/L biomass) , while CTWY17 grew the fastest by

shaking flask cultivation in glucose. The results show that the isolated yeasts could be

promising candidates for biodiesel production.

Page 23: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 23 -

Moring, November 13, 2016 (Sunday)

Time: 11:00~12:30

Venue: 西特廰 (Room No.204)

Session 1: 6 presentations-Topic: “Agriculture and Biotechnology”

Session Chair: Assoc. Prof. KUO-YUAN HWA

B3001 Presentation 5 (12:00~12:15)

Mass Cultivation and Antifungal Activity of Microbial Agents for Farming

Kong-Min Kim, Ki Moon Bong, Jae-Hong Yoo, In Chul Park and Pyoung Il Kim

Bio Control Research Institute, Jeonnam Bioindustry Foundation

Abstract—Effective microorganisms are utilized to promote crop growth, soil improvement,

immune activity and pest control in the agricultural fields. In this study, we examined the

optimal culture conditions for mass production of two microbial strains such as Bacillus sp.,

and Pseudomonas sp.. These microorganisms were kindly provided by Korean Agriculture

Culture Collection (KACC), Rural Development Administration (RDA), Republic of Korea.

It was established to the optimal culture conditions such as media compositions, pH range and

incubation periods. Bacillus strain was cultured in 500 L fermenter as follows; soy peptone 5

g, sucrose 20 g per liter, pH 6.8. After incubation for 24 h, Bacillus strain was developed the

vegetative cells to the endospores (2 ⅹ 109 cfu/ml). The optimal culture conditions of

Pseudomonas strain were also determined as follows; soy peptone 20 g, glucose 5 g, NaCl 5 g,

K2HPO4 2.5 g, LiCl 2.5 g per liter, pH 6.5 and incubation period 38 h. After cultivation of

two bacterial cells, the cell free supernatants exhibited antifungal activity against five plant

pathogenic fungi. Finally, the antifungal lipopeptides produced by bacterial cells were

identified using LC-MS instruments.

Page 24: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 24 -

Moring, November 13, 2016 (Sunday)

Time: 11:00~12:30

Venue: 西特廰 (Room No.204)

Session 1: 6 presentations-Topic: “Agriculture and Biotechnology”

Session Chair: Assoc. Prof. KUO-YUAN HWA

B3002 Presentation 6 (12:15~12:30)

Statistical optimization of nutritional medium constituents for carotenoid production by

Rhodobacter sphaeroides PS-24

Ki Moon Bong, Kong-Min Kim, Jae-Hong Yoo, In Chul Park and Pyoung Il Kim

Bio Control Research Institute, Jeonnam Bioindustry Foundation

Abstract—Response Surface Methodology (RSM), combining Plackett–Burman design with

Box-Behnken experimental design, was applied to optimize the concentrations of different

nutrient components in liquid fermentative medium for carotenoids production by

Rhodobacter sphaeroides PS-24. Nine nutrient ingredients containing yeast extract, K2HPO4,

MgSO4, sodium acetate, NaCl, mono-sodium glutamate, Na2CO3, NH4Cl and CaCl2 were

finally selected to optimize the medium composition based on their statistically significant

and positive effects on carotenoid yield. Box-Behnken design was used for further

optimization of those selected nutrient component in order to increase carotenoid production.

By stepwise analysis the data obtained from Box-Behnken, the secondary order coefficient

model was set up to identify the relationship between the carotenoid productivity and these

nutrient ingredients. The important factors having influence on optimal medium constituents

and culture condition for carotenoid production by Rhodobacter sphaeroides PS-24 were

identified as follows: yeast extract 10.45 g/L, sodium acetate 0.75 g/L, NH4Cl 1.75 g/L and

the other components of fermentative medium were kept the same as modified Van niel’s

medium (NaCl 2.5 g/L, K2HPO4 2 g/L, MgSO4 0.5, monosodium glutamate 7.5 g/L,

Na2CO3 2.2 g/L, CaCl2 0.01 g/L). Maximum carotenoid yield of 18.05 mg/L was produced

by confirmatory experiment in the optimum medium after 36 h fermentation.

Lunch

12:30~13:30 Restaurant

Page 25: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 25 -

Session 2

Tips: The schedule for each presentation is for reference only. In case of missing your presentation,

we strongly suggest that you attend the whole session.

Afternoon, November 13, 2016 (Sunday)

Time: 13:30~15:15

Venue: 西特廰 (Room No.204)

Session 2: 7 presentations-Topic: “Bioinformatics and Computational

Biology”

Session Chair: Prof. David Zhang

E0005 Presentation 1 (13:30~13:45)

Algorithm for Segmentation and Reduction of Fractured Bones in Computer-Aided

Preoperative Surgery

Irwansyah Idram, Jiing-Yih Lai, Terence Essomba and Pei-Yuan Lee

National Central University, Taiwan

Abstract—CT images have extensively been used for the diagnosis of serious bone injuries,

such as comminuted fracture, and for the preoperative planning of orthopedic surgery. In

order to enhance the use of CT images in preoperative planning, it is necessary to develop a

3D modeling and simulation tools to acquire more information regarding the real surgery.

Bone segmentation and reduction are two important simulation tools in computer-aided

preoperative surgery. By improving both algorithms can affect to the feasibility of 3D

preoperative planning for fractured bones and provide more valuable information prior to

decision making. We provide a technique to model, segment and recover fractured bone from

CT images. A multi-region segmentation algorithm is proposed to reduce processing time

and get efficiency. A manual and a semi-automatic bone reduction algorithm are proposed to

deal with different kinds of fractured bone cases. Two semi-automatic bone reduction

algorithms, multi-point and mirror positioning, are proposed to improve the efficiency of

manual reduction. The manual reduction is still necessary to deal with cases which cannot be

caught by the semi-automatic algorithms. Several realistic examples by using real patients’

CT images are provided to illustrate the feasibility of the proposed method.

Page 26: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 26 -

Afternoon, November 13, 2016 (Sunday)

Time: 13:30~15:15

Venue: 西特廰 (Room No.204)

Session 2: 7 presentations-Topic: “Bioinformatics and Computational

Biology”

Session Chair: Prof. David Zhang

E0012 Presentation 2 (13:45~14:00)

A Novel Framework for Repeated Measurements in Diffusion Tensor Imaging

Mohammad Alipoor, Irene Y.H. Gu, Andrew Mehnert, Göran Starck and Stephan E. Maier

Chalmers University of Technology, Sweden

Abstract—In the context of diffusion tensor imaging (DTI), the utility of making repeated

measurements in each diffusion sensitizing direction has been the subject of numerous studies.

One can estimate the true signal value using either the raw complex-valued data or the

real-valued magnitude signal. While conventional methods focus on the former strategy, this

paper proposes a new framework for acquiring/processing repeated measurements based on

the latter strategy. The aim is to enhance the DTI processing pipeline by adding a diffusion

signal estimator (DSE). This permits us to exploit the knowledge of the noise distribution to

estimate the true signal value in each direction. An extensive study of the proposed

framework, including theoretical analysis, experiments with synthetic data, performance

evaluation and comparisons is presented.

Our results show that the precision of estimated diffusion parameters is dependent on the

number of available samples and the manner in which the DSE accounts for noise. The

proposed framework improves the precision in estimation of diffusion parameters given a

sufficient number of unique measurements. This encourages future work with rich real

datasets and downstream applications.

Page 27: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 27 -

Afternoon, November 13, 2016 (Sunday)

Time: 13:30~15:15

Venue: 西特廰 (Room No.204)

Session 2: 7 presentations-Topic: “Bioinformatics and Computational

Biology”

Session Chair: Prof. David Zhang

E0017 Presentation 3 (14:00~14:15)

Tactile Sensor for Cardiovascular Catheters

Chao-Hsien Huang, Cheng-Hung Shih and Nai-Jun An

Metal Industries Research & Development Centre, Taiwan

Abstract—Tactile sensor are widely used in different biomedical purposes. For more safe

operation during cardiovascular surgery, the force signal feedback for doctor is very important.

Therefore, the tactile sensor is one of potential technique to guiding the catheter when the

contact parttouch the blood vessel. In this study, we change the tactile sensor using

pressure-based mechanism to force-based mechanism, which improving the signal resolution

at higher contact angle between catheter and blood vessel. The prototype of assembled tactile

sensor are designed and fabricated, and the mechanical and electrical performance of

compressible diaphragm are evaluated.

Page 28: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 28 -

Afternoon, November 13, 2016 (Sunday)

Time: 13:30~15:15

Venue: 西特廰 (Room No.204)

Session 2: 7 presentations-Topic: “Bioinformatics and Computational

Biology”

Session Chair: Prof. David Zhang

E0019 Presentation 4 (14:15~14:30)

Development Of a Swordsmanship Machine Enabling the Inner and Outer Muscles to Be

Safely Trained While Having Fun

Kiyoshi Hoshino and Chuanhan Cheng

University of Tsukuba, Japan

Abstract—The objective of the study is to design and develop a “swordsmanship machine”

characterized in that it has easiness to play the game, safety, and entertainment, aiming at, first,

understanding and promotion of martial arts such as Japanese Kendo and close quarter

combat with short bamboo sword “Tankendo”; and secondly, training of the inner and outer

muscles while having fun to enhance health and prevent, in particular, the elder from tripping

and falling down. The mechanism of arms/shoulders of the machine that we introduce in the

present paper is composed of five-bar closed link mechanism for the upper limb motions, as

well as four-bar link mechanism for the wrist motion, respectively. These linkages give the

machine high damping properties, good positioning accuracy, and high rigidity of the entire

structure.

Page 29: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 29 -

Afternoon, November 13, 2016 (Sunday)

Time: 13:30~15:15

Venue: 西特廰 (Room No.204)

Session 2: 7 presentations-Topic: “Bioinformatics and Computational

Biology”

Session Chair: Prof. David Zhang

E0020 Presentation 5 (14:30~14:45)

Hand Motion Capture for Medical Usage

Kiyoshi Hoshino, Sota Sugimura, Motomasa Tomida, Naoki Igo, Isao Kawano and Masahiko

Sumitan

University of Tsukuba, Japan

Abstract—The authors propose, not a non-contact devise which our research group has been

developing, but a compact wearable device which allows for estimation of the hand pose

(hand motion capture) of the subject. The devise has a miniature wireless RGB camera on the

back side of user’s hand, rather than the palm side. Attachment of the small camera on the

back side of the hand may make it possible to minimize the restraint on the subject’s motions

during motion capture. The conventional techniques attach the camera on the palm side of the

hand for the reason that the images of fingertips always need to be captured by the camera

before any other parts of the hand. In contrast, our image processing algorism, the authors

propose here, is capable of estimating the hand pose with no need for capturing first the

fingertips. Our system allows doing hand and finger motion capture without his psychological

burden and physical constraints in clinical diagnosis.

Page 30: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 30 -

Afternoon, November 13, 2016 (Sunday)

Time: 13:30~15:15

Venue: 西特廰 (Room No.204)

Session 2: 7 presentations-Topic: “Bioinformatics and Computational

Biology”

Session Chair: Prof. David Zhang

E0021 Presentation 6 (14:45~15:00)

Measurement of Rotational Eye Movement with Blue Light Irradiation

Kiyoshi Hoshino, Nayuta Ono, Motomasa Tomida and Naoki Igo

University of Tsukuba, Japan

Abstract—It is difficult to measure rotational eye movement constantly from ”almost black

eyeball image” acquired under the condition that the brightness of an image content being

watched by a user is very low or the condition that almost no light is irradiated from its

surrounding environment. To solve this problem, turning our attention to the “conjunctival

blood vessel ends” located on the periphery of the iris, which are not affected by the changes

in pupil diameter, as well as small “blue LED light” irradiation as auxiliary light, the authors

developed a new method for measuring rotational eye movement at high accuracy by

enhancing the contrast in the image of the vessels on the white of the eyeball. This paper

proposes the above-mentioned new method to enable a measuring system, which is not

subject to the changes in pupil diameter and eyelid closure, and has been compactly-designed

in terms of both software and hardware with a miniature camera. In our evaluation experiment,

the images of rotational eye movements were captured, and data on the vessel end positions

were obtained by both visual measurement and this system to evaluate the estimated error and

processing speed. The result suggests that our proposed system is capable of measuring

rotational eye movement with an average of estimated errors equal to or lower than 0.24

degrees, even with almost black eyeball image.

Page 31: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 31 -

Afternoon, November 13, 2016 (Sunday)

Time: 13:30~15:15

Venue: 西特廰 (Room No.204)

Session 2: 7 presentations-Topic: “Bioinformatics and Computational

Biology”

Session Chair: Prof. David Zhang

E0022 Presentation 7 (15:00~15:15)

Measurement of Rotational Eye Movement with Blue Light Irradiation

Josimar Edinson Chire Saire and Yvan Tupac

Research Center in Computer Science Universidad Católica San Pablo

Abstract—The Evolutionary Algorithms have main features like: population, evolutionary

operations (crossover, mate, mutation and others). Most of them are based on randomness and

fol low a criteria using tness like selector. The FP-AK-QIEAR uses probability density

function according to best of initial population to sample new population and uses rewarding

criteria to sample around the best of every iteration using cumulative density function

estimated for Akima interpolation, it was used for mono-objective problems showing good

results. The proposal uses the algorithm FP-AK-QIEAR and add Pareto dominance to

experiment with multiobjective problems. The performed experiments use some benchmark

functions from the literature and initial results shows a promissory way for the algorithm.

15:15-15:30 Coffee Break

Page 32: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 32 -

Session 3

Tips: The schedule for each presentation is for reference only. In case of missing your presentation,

we strongly suggest that you attend the whole session.

Afternoon, November 13, 2016 (Sunday)

Time: 15:30~17:30

Venue: 西特廰 (Room No.204)

Session 3: 8 presentations-Topic: “Chemical Engineering and Technology”

Session Chair: Assoc. Prof. Chi-wai KAN

C0002 Presentation 1 (15:30~15:45)

Prediction of the Vapor–Liquid Equilibrium of Formaldehyde–Water–Trioxane Ternary

System by the Conductor-like Screening Model for Real solvents

Huihong Liu, Zhenmin Bai, Yansheng Liu, XuqiangGuo and Yu’eFu

China University of Petroleum (Beijing)/ China Bluechemical Ltd., CNOOC, China

Abstract—In this study, a thermodynamic model was combined with the conductor-like

screening model for real solvents (COSMO-RS), coupled with chemical reaction equilibrium

and mass balance, for describing the phase behavior and complex chemical equilibrium in the

ternary system of formaldehyde–water–trioxane at temperatures between 413 K. New

approach for the prediction of vapor-liquid equilibrium of the binary system (TOX + W) and

the ternary system (FA+W+TOX) is compared with experimental data and UNIFAC method.

The calculated vapor–liquid equilibrium (VLE) result shows good agreement with the

experimental data. The COSMO-RS model has proven to be an accurate and effective method

for predicting the activity coefficient, and also more reasonable for predicting the

thermodynamic properties of formaldehyde–water–methanol reactive fluids.

Page 33: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 33 -

Afternoon, November 13, 2016 (Sunday)

Time: 15:30~17:30

Venue: 西特廰 (Room No.204)

Session 3: 8 presentations-Topic: “Chemical Engineering and Technology”

Session Chair: Assoc. Prof. Chi-wai KAN

C0004 Presentation 2 (15:45~16:00)

Prediction of Vapor-Liquid Equilibrium Properties for the Mixture of Propylene+Propane

from the Combined Use of Peng-Robinson Equation of State and Cosmo-Rs Model

Xinyun Pu, Lehuan Wu and Yansheng Liu

China University of Petroleum (Beijing), China

Abstract—In this research, the prediction of vapor-liquid equilibrium (VLE) of the binary

mixture of propylene+propane from the combined use of the Peng-Robinson equation of state

(PR-EOS) and the COSMO-RS model is examined. Following the Van der Waals mixing rule

(VdW), the average deviations in both the pressure and vapor phase composition from the

method are no more than 0.32% and 0.57%, respectively. Based on the results, it has been

shown that PR-EOS+VdW+COSMO-RS is a promising approach for propylene+propane

VLE predictions over a wide range of temperatures. This method introduces only one

adjustable parameter. Assuming the adjustable parameter as a function of temperature, this

method is used as a straight forward process without any iteration to estimate VLE data.

Page 34: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 34 -

Afternoon, November 13, 2016 (Sunday)

Time: 15:30~17:30

Venue: 西特廰 (Room No.204)

Session 3: 8 presentations-Topic: “Chemical Engineering and Technology”

Session Chair: Assoc. Prof. Chi-wai KAN

C0005 Presentation 3 (16:00~16:15)

Solvent Screening for Cyclopentane Purification Based on COSMO-RS

Lehuan Wu, Xinyun Pu and Yansheng Liu

China University of Petroleum (Beijing), China

Abstract—Separation of cyclopentane has an important significance in environmental

protection and resource utilization. This work is intended to serve as a rapid way to screen

mixed solvent for extractive distillation of cyclopentane using the COSMO-RS method.

IDACs and VLE data of different binary systems were compared with computational results.

Then the performance of mixed solvent was studied by the COSMO-RS method, including

the influences of the solvent-to-feed ratio and the basic solvent and cosolvent ratio on the

relative volatility. Finally, the mixed solvent was validated to be effective by the experiments.

Page 35: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 35 -

Afternoon, November 13, 2016 (Sunday)

Time: 15:30~17:30

Venue: 西特廰 (Room No.204)

Session 3: 8 presentations-Topic: “Chemical Engineering and Technology”

Session Chair: Assoc. Prof. Chi-wai KAN

C0007 Presentation 4 (16:15~16:30)

Schiff Base Transition Metal Complexes for ROP of L-Lactide

S Mantri, H. C. Pradhan, T Maharana

and Alekha Kumar Sutar

Ravenshaw University, India

Abstract—A Series of Schiff base transition metal complexes have been synthesized and its

reactivity for the ring-opening polymerization (ROP) of lactide has been studied. These metal

complexes were synthesized by the reactions of metal salt solution with one molar equivalent

of bulky Schiff-base ligand in methanol under nitrogen atmosphere. These complexes have

been tested as initiators for the ring-opening polymerization of lactide with variation of

concentration, time, solvent, etc. The transition metal complexes allow controlled

ring-opening polymerization as shown by the linear relationship between the percentage

conversion and the number-average molecular weight.

Page 36: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 36 -

Afternoon, November 13, 2016 (Sunday)

Time: 15:30~17:30

Venue: 西特廰 (Room No.204)

Session 3: 8 presentations-Topic: “Chemical Engineering and Technology”

Session Chair: Assoc. Prof. Chi-wai KAN

C0008 Presentation 5 (16:30~16:45)

Polymer Supported Schiff base Iron Complex for Epoxidation of trans-Stilbene

N. Natha, H. C. Pradhanb, Tungabidya Maharana and A. K. Sutar

National Institute of Technology, Raipur, India

Abstract—In the present investigation, the novel recyclable polystyrene anchored iron

complex supported by –ONN Schiff base is synthesized. This polymer anchored iron complex

is prepared by the reactions of metal solution with one molar equivalent of polystrene

supported Schiff-base ligands in methanol under nitrogen atmosphere. In contrast with other

polymer-supported catalysts, the greatest advantage of this catalyst system was that the cost of

the catalyst was remarkably low and recycled up to six times, due to the easily accessible

materials and the simple synthetic route. The higher efficiency of complexation of metal ions

on the polymer anchored Schiff base than unsupported analogue was another advantages of

this catalyst system. The structural study reveal that iron(III) complex is octahedral in

geometry. The catalytic activities of polystyrene supported iron complex toward the

epoxidation of trans-Stilbene is investigated. Experimental results indicate that the reactivity

of iron complex is dramatically affected by the polymer support and the rate of trans-Stilbene

conversion was 4.27 x 10-7 moledm-3s-1 and obeys first order kinetics. The efficiency of

supported catalysts remained almost constant upto six recycles.

Page 37: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 37 -

Poster Session

Tips: The poster session will last from 8:30 to 17:30. Please provide your home-made poster to the

conference specialist in advance before the conference beginning.

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

B0017 (8:30~17:30)

Classification of Cardiac Arrhythmias Using Ensemble Classifiers with Reduced Features

Zeynep Beyza Zileli and Niyazi Kilic

Istanbul University, Turkey

Abstract—Ensemble learning algorithms are one of the most popular pattern classification

methods. In this study, electrocardiogram (ECG) records are investigated to classify them as

arrhythmia or normal sinus. Various classifiers such as REPTree, K- Nearest Neighbour

Classifier (k-NN) and support vector machines (SVM) are performed as base learners of

ensemble learning algorithms. At the same time, adaboost, bagging and random subspaces

(RSS) ensemble learning algorithms are utilized and compared each other. Besides, random

subset filter are used for reduced dimension of data. When obtained results with reduced

features are examined, the highest percentage of accuracy achieved without the using of

ensemble algorithm (individual classifier) is obtained with the support vector machine as

78.68%. While the support vector machines are used with random subspace method, accuracy

has been observed as 85.29 %. These results show that ensemble classifiers are more useful

than individual classifiers to classify cardiac arrhythmias.

Page 38: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 38 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

B0018 (8:30~17:30)

Design and Implementation of Software Based Audiometer System

Mehmet Cem Catalbas and Hasan Guler

Firat University, Turkey

Abstract—This paper proposes design and implementation of software based audiometer

using LabVIEW. In this study, basic definition and test procedure of audiometer are explained.

The implementation of audiometer is realized by LabVIEW. The most preferred clinical

audiometer method (Modified Hughson-Westlake) is selected for study. The test procedure

and audiometer implementation are explained by structure of binary case system. The ambient

noise level is determined by decibel meter used in calibration. Besides, audiometer calibration

process is performed for successful and realistic results. The calibration process is

implemented by polynomial fitting. Furthermore, configurable white noise is used for

minimizing interference between active and passive sound channel on duration of audiometer

test. As a result, this paper achieves implementing a pure tone audiometer based LabVIEW

with channel masking.

Page 39: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 39 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

E0001 (8:30~17:30)

Fluctuation Characteristics of NO2 Pollution over Yangtze River Delta during the Period of

Global Financial Crisis

Yin Du and Zhiqing Xie

Nanjing University of Information Science & Technology (NUIST), China

Abstract—Using the NO2 density data from the Ozone Monitoring Instrument (OMI) and

ground-based observations, the effects of industrial fluctuations due to the financial crisis on

local NO2 pollution are quantitatively assessed. The results are as follows. (1) The global

financial crisis caused distinct V-shaped fluctuations from May2007 to Dec2009 and the

largest anomalies of more than 1.5 times the standard deviations at the height of the crisis

period of Nov2008 to Feb2009, for major industrial products, thermal generating capacity,

electricity consumption, and tropospheric NO2 densities. (2) Among all industrial sectors, the

thermal power sector was mainly responsible for fluctuations in local NO2 pollution during

the crisis period. Especially, in the Yangtze River Delta, the thermal power sector has the

greatest share of coal consumption, namely 65.96%. Since electricity is mainly obtained from

local coal-burning thermal plants without NOx-processing equipment, installing

NOx-removal devices for all thermal power plants is at present an important, feasible way of

controlling local NOx pollution.

Page 40: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 40 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

E0003 (8:30~17:30)

Analysis of the FGOALS Simulation on East Asian Westerly Jet in CMIP5 during the Meiyu

Season

Yin Du and Zhiqing Xie

Nanjing University of Information Science & Technology (NUIST), China

Abstract—Based on the Coupled Model Inter-comparison Project (CMIP5) coordinated

experiments simulated by the IAP Flexible Global Ocean-Atmosphere-Land System Model

(FGOALS), the properties of the East Asian Westerly Jet (EAWJ) during the Meiyu season

have been investigated with the using statistical analysis, kinetic and thermodynamic methods.

FGOALS can well capture the land and sea patterns of the EAWJ during the Meiyu period,

which is that patterns of the EAWJ mainly core divided by the borderline of 120°E.

Comparison with the NCEP/NCAR reanalysis, the EAWJ simulated by the FGOALS model

during the Meiyu period exists some biases, which are caused due to weaken of the simulated

meridional temperature gradient at the middle and upper troposphere and decrease of the

Tibetan Plateau heating, then lead to the corresponding south Asian high weaken. The

position and intensity of the EAWJ in the early summer is closely associated with the spatial

distribution and intensity of heavy precipitation in the middle and lower reaches of the

Yangtze River. The position of the simulated EAWJ is obviously more northward and

westward, and its intensity is greatly weaker, insulted that the Meiyu precipitation amount

becomes less, especially in the lower reach of the Yangtze River.

Page 41: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 41 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

E0007 (8:30~17:30)

Study on Ratcheting Behavior of Trabecular Bone with and without Marrow under Cyclic

Compression

Chao-lei Wei, Li-lan Gao and Chun-qiu Zhang

Tianjin University of Technology, China

Abstract—One of the major functions of bone is to provide structural support. So it is

important to study its mechanical behavior. The aim of this study was to investigate the

ratcheting behaviors of trabecular bone under cyclic compression and the effect of marrow on

the ratcheting strain of trabecular bone. So a series of tests were conducted for the rectangular

trabecular bone samples. It is found that the initial ratcheting strain of trabecular under cyclic

compressive load increases rapidly, and then its increasing rate keeps on a small value. The

relationship between the reduction of marrow and the evolution of mechanical properties of

trabecular bone was obtained and the microscopic deformation of tissue was observed with

the help of the optimized digital image correlation (DIC) technique. It was found that the

marrow can enhance the mechanical strength of trabecular bone to a large extent.

Simultaneously, the ratcheting strain of trabecular bone along its depth was basically same.

Page 42: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 42 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

E0009 (8:30~17:30)

Mechanical Behavior of Articular Cartilage Soaked in Physiological Saline under Cyclic

Compressive Loading

Dong-dong Liu, Li-lan Gao and Xiao-yi Qin

Tianjin University of Technology, China

Abstract—The ratcheting deformation of articular cartilage can be produced due to the

repeated accumulations of compressive strain. The aim of this study was to investigate the

ratcheting behavior of articular cartilage under cyclic compression. A series of cyclic

compressive tests with different stress amplitudes and stress rates were conducted for pig knee

articular cartilage, which was soaked in physiological saline. It is found that the ratcheting

strain increases with rising of stress amplitude, while it decreases with rising of stress rate.

The initial ratcheting strain of articular cartilage under cyclic compressive load increases

rapidly, and then it exhibits a relatively stable status. The change of Young’s modulus for

cartilage is the same as evolution of ratcheting strain. Simultaneously, the optimized digital

image correlation(DIC) technique was applied to study the ratcheting behavior of different

layers for cartilage of online soaked under cyclic compression. It is found that the ratcheting

behavior of cartilage is dependent on its depth. These results can provide the basis for disease

treatment of clinical cartilage and cartilage defect repair.

Page 43: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 43 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

E0010 (8:30~17:30)

Research on the Factors of Colonoscopy Screening Compliance in High-Risk Colorectal

Cancer Groups

MA Hong-mei and LU Jian-hong

Tianjin People’s Hospital, China

Abstract—At present, the colonoscopy rate of colorectal cancer in urban residents is low. In

order to acknowledge colonoscopy screening compliance of colorectal cancer high-risk of

urban community residents and its influencing factors is for the purpose of targeted nursing

intervention to improve compliance, to provide basis for colorectal cancer screening. The

authors take colorectal cancer screening high-risk groups sample from community in Tianjin

as the research object, according to whether be willing to accept endoscopic check, put them

into the case group and the control group. Designed the general questionnaire colorectal

cancer screening and colonoscopy cognitive questionnaire and refusing colonoscopy

questionnaire for patients at high risk of colorectal cancer, using Delphi method to get final

questionnaire, to get the influence factors of colorectal cancer high-risk patients receiving

endoscopic check. Through the data analysis, we draw that only whether of health care

between groups in all of the characteristics has statistically significant difference (P < 0.05),

and others like gender, marriage, culture degree, family income, etc. has no statistical

difference (P > 0. 05).Two groups has significant statistical difference in the colonoscopy

cognitive (P < 0.05).At the same time, busy work and no time are the major causes of refusing

to colonoscopy, with constituent ratio at 35%. After discussion, we consider that increasing

cognitive of colorectal cancer screening colonoscopy and targeted to intervention of refusing

colonoscopy related factors, could improve the colonoscopy screening compliance in patients

with high risk of colorectal cancer, so as to improve the compliance of the screening work.

Page 44: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 44 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

E0011 (8:30~17:30)

Biocompatibility Evaluation of Organic Acid-Decellularized Based Methods on Porcine

Corneal Scaffold

Hung-Jun Lin, Ting-Wei Li, Ping-Lun Jiang, Chon-Ho Yen, Ching-Fu Tu, Ming-Thau Sheu,

Yi-You Huang and Der-Zen Liu

National Taiwan University, Taiwan

Abstract—Cornea disease is one of the main reasons of blindness, and the major treatment is

allogeneic corneal transplant. Due to lack of supplements of donor corneas, it’s urgent to

develop bioengineered corneal scaffolds to make recovery of the version. Decellularized

corneal xenograft scaffolds are thought to be great transplant substitutes for their natural ECM

and biologic factors, and porcine is one of the greatest animal resources for its similar

biological characteristics to human. The aim of this study was to establish organic

acid-decellularized porcine corneal scaffolds, and to recellularize corneal keratocytes into

decellularized scaffolds. The corneas were dissected from porcine, and then soaked in formic

acid, acetic acid or critic acid solutions at 25℃ for 72h on an orbital shaker. After

decellularized procedure, the corneal scaffolds were washed by PBS until pH value to 7. The

cells removal efficacy was examined by Qubit DNA assay, and ECM reservation was

examined by GAGs and Collagen assay. The results showed over 90% porcine cells was

eliminated after decellularized procedure. Compared with native corneas, the decellularized

corneal scaffolds had similar GAGs and Collagen contents. The SEM images confirmed the

decellularized corneal scaffolds remained uniform parallel microstructure, and showed porous

structure which might be beneficial for further keratocytes recellularization. After UV light

sterilization, the decellularized corneal scaffolds were seeded with keratocytes, SIRC cells for

1 weeks. MTT assay demonstrated keratocytes well proliferated on the decellular corneal

scaffolds. Taken together, these results showed the organic acid-decellularized based

decellularized corneal scaffolds had great potential to be corneal transplantation substitutes.

Page 45: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 45 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

E0013 (8:30~17:30)

Numerical Simulation of the Adenoidectomy Preoperative and Postoperative Upper Airway in

Children with OSAHS

Gang Wang, Chi Yu and Jing Zhang

Dalian University, China

Abstract—Obstructive sleep apnea hypopnea syndrome (OSAHS) is a highly prevalent and

potentially risky disease. Hypertrophic adenoids are a fundamental cause of pediatric

secretory otitis media, sinusitis and snoring. And then the nostril jams and eustachian tube

swallow mouth oppression is the main factor of adenoid hypertrophy. The present study takes

computational fluid dynamics (CFD) approach to assessing postoperative effect in children

with OSAHS undergoing adenoidectomy by comparison of the flow field characteristics

between postoperative with preoperative upper airway. The computational fluid dynamics

models were constructed using raw data from preoperative and postoperative computed

tomogram images of three children with OSAHS. The surgical operation altered the abnormal

anatomy of the upper airway. The whole upper airway resistance decreased significantly. It is

shown that the airflow patterns in postoperative nasopharyngeal airway are significantly

different from preoperative subjects.

Page 46: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 46 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

E0014 (8:30~17:30)

Analysis of Methicillin-resistant Staphylococcus Aureus Using Apriori, DBSCAN, and

K-means Algorithms

Min Young Lee and Taeseon Yoon

Hankuk Academy of Foreign Studies, Republic of Korea

Abstract—Known as the most virulent “super-bacteria,” methicillin-resistant staphylococcus

aureus (MRSA) is a bacterium that has developed a multi-resistance to standard types of

antibiotics, including the penicillins and cephalosporins. Such difficulty to treat with

antibiotics exposes MRSA patients to a severe danger—even to death—especially those who

possess weakened immune systems. In attempts to create effective antibiotics for MRSA,

previous researches have focused on proteins in localized areas of the genome. This research,

however, aims to suggest a new angle of MRSA by analyzing the entire genome through

bioinformatics. The research utilizes three data mining techniques: Apriori algorithm,

DBSCAN algorithm, and K-means algorithm. Apriori algorithm shows that Leucine is

predominant in the genome, a characteristic similar to pathogens that cause malaria, dengue,

and lung cancer. DBSCAN algorithm and K-means algorithm provide a surprising result:

while MRSA genome may seem like a lump of leucine, it actually consists of two separate

parts, with a ratio of 7 to 3. This result suggests that each region may have evolved differently

from the original strain of MRSA, or, only one of the two regions may account for the

multi-resistance of MRSA, while the other serving another purpose.

Page 47: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 47 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

C3002 (8:30~17:30)

Development of Superhydrophobic Silk Fabrics using Alkaline Hydrolysis

Sujin Lee, Suhyun Lee and Chung Hee Park

Seoul National University, South Korea

Abstract—This research was carried out in order to develop silk fabrics with dual scale

surface roughness and that show hydrophobicity and self-cleaning properties, employing

alkaline treatment process, the current conventional silk degumming method. Surface

roughness of 100% raw silk fabric was controlled by varying the degumming temperature and

time in a 0.1 M NaOH solution to adjust the extent of sericin dissolution. Hydrophobization

was carried out by depositing n-dodecyltrimethoxysilane (DTMS) through the chemical vapor

deposition (CVD) method. The surface morphology, surface chemical composition, weight

loss, tensile strength, luster, and color change were evaluated, and the surface wettability was

evaluated by water contact angles and shedding angles.

As the temperature and time of alkaline treatment increased, the weight loss increased, and

the tensile strength decreased, particularly at higher temperatures and longer times. It was

observed that the sericin on the fiber surface dissolved in the alkaline solution and formed

nanoclusters. Owing to this nanoscale roughness on the fabric surface through alkaline

treatment, contact angle increased from 0° to 152° after hydrophobic coating, and shedding

angle decreased from 90° to 15°, which indicated outstanding superhydrophobicity. Therefore,

condition for developing a self-cleaning silk fabric, maintaining physical properties such as

tensile strength, luster and color, while exhibiting outstanding superhydrophobicity.

This research has a great significance in the successful development of a silk fabric that

shows self-cleaning properties with minimum damage to its appearance, which was the

concerned obstacle for its processing, leading to a new way for the development of functional

silk fabrics in the future.

Page 48: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 48 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

C3003 (8:30~17:30) Fabrication of Single-faced Superhydrophobic Polyester Fabric Via Alkaline Hydrolysis and Blade Coating

Kirim Kim, Seon Young Youn and Chung Hee Park Seoul National University, South Korea

Abstract—The purpose of this study was to develop a single-faced superhydrophobic

polyester fabric with improved breathability and self-cleaning properties by using the

conventional alkaline hydrolysis and a blade coating. Alkaline hydrolysis using dilute NaOH

aqueous solution was used to form the micro and nano dual scale roughness on the surface of

fiber. The surface roughness was implemented by controlling the alkaline treatment time and

temperature, and the optimal conditions of the alkaline treatment were selected in

consideration of the surface roughness and the rate of tensile strength loss. Customized

composite foam coating emulsions were prepared by adjusting the volume concentration of

the fluoropolymer using a thickener with controlled viscosity. Experimental variables, such as

alkaline treatment time and temperature, were investigated to find the optimal conditions of

the alkaline treatment. Chemical and morphological changes, such as fiber surface, thickness,

weight, diameter, and tensile properties, were investigated. Then, the contact angle (CA) and

shedding angle (SHA) for each side of the hydrophobized PET were measured to find the

optimal conditions of single-faced superhydrophobicity. The washing durability test were also

examined.

As the alkaline treatment time and temperature increased, the finely formed nano roughness

was developed, which was effective to fabricate the superhydrophobic surface. Meanwhile,

the low viscosity of the foam emulsion was desirable to maintain the surface roughness. In

this study, a PET fabric with extreme asymmetric wettability was achieved: a face side

showing excellent superhydrophobicity and a back side achieving hydrophilicity due to e

chemical etching. The face side exhibited a CA of 162.8° and a SHA of 5.6°, while the back

side showed hydrophilicity such that it was completely absorbed on the surface within 109

seconds. The optimal condition of the single-faced superhydrphobic PET was as follows: The

PET was treated at alkaline temperatures at 70°C for 60 minutes and hydrophobized with a

composite foam with a volume ratio of fluoropolymer to thickener of 40 : 2. In this study,

conventional polyester alkaline hydrolysis was used to develop a single-faced

superhydrophobic PET by using low concentrations of the NaOH solutions, which minimized

the tensile strength loss and enhanced the breathability and wearer comfort at the same time.

This technology presents the possibility of industrial-scale manufacturing to generate proper

micro-nano surface roughness to create superhydrophobic PET by replacing the typical

technology of nano-particle applications with many side effects.

Page 49: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 49 -

November 13, 2016 (Sunday)

Time: 8:30~17:30

Venue: 西特廰 (Room No.204)

C3004 (8:30~17:30)

Superhydrophobicity of Nanostructured Conductive Fabric Treated with Cf4 Plasma and

Water Immersion Treatment

Sohyun Park, Hey-sang Kim, Kyungha Baik and Chung Hee Park

Seoul National University, South Korea

Abstract—Wearable device, a textile-based components integrated by various electrical

materials, is easy of losing their smart functions by water. It is important that a textile-based

components of wearable device has anti-wettability by Superhydrophobic finishing for a wide

range of applications. If superhydrophobic finishing was applied to wearable devices to give it

anti-wettability, wearable devices would be used at more various fields. Therefore,

superhydrophobic surface with nano-scale clusters covered with hydrophobic layer on

metal-coated conductive fabrics was developed through plasma and water immersion

treatment in this study.

Superhydrophobic surface and electrically conductive nickel-copper coated fabric was

prepared by following three treatments: 1) plasma treatment, 2) water immersion to occur

fluorination reaction with plasma treated surface, and 3) plasma enhanced chemical vapor

deposition of hexamethyldisiloxane (O[Si(CH3)3]2; HMDSO) of nikel-copper coated fiber.

The treated fabrics had static contact angles (CA) of 159.5° and the shedding angle (SA) of

3.6°. The incorporation of CF4 etching and subsequent water immersion considerably

improved surface roughness by forming nano-scale clusters. In water, a catalytic reaction of

fluorine ions on metal coated surfaces improved surface roughness by forming clusters on the

fiber surface. The treated fabrics maintained its original electric resistance which is in the

range of 0.025─0.041 Ω. It was interesting to note that the modification of surface

morphology has little impact on the samples’ intrinsic conductivity. These multi-functional

fabrics would be relevant for smart textiles of wearable device which require water repellent

or self-cleaning and electro-conductive properties.

Dinner

18:00 Restaurant

Page 50: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 50 -

Conference Venue

GIS TAIPEI TECH Convention Center, Taiwan

(集思北科大會議中心)

http://www.meeting.com.tw/index.php/contact-us/796-contact-ntnu

TEL ( 電話): (02) 2741-7655, FAX(傳真): (02) 2741-8699

Address (地址): 億光大樓 2~3樓 (Sec. 3, Zhongxiao E. Rd., Taipei 10608 Taiwan, 台北市忠孝東路三

段 193巷旁) E-mail (信箱): [email protected]

Map to the venue place

Recommend Hotels (Close to the venue):

凱統飯店(KDM HOTEL): 106 台北市大安區忠孝東路三段 8號 (No. 8, Section 3, ZhongXiao East

Road, Da'an District, 106 Taipei, Taiwan)

美麗信花園酒店(THE MIRAMAR GARDEN TAIPEI): 104 台北市中山區市民大道三段 83 (No. 83,

Civic Boulevard, Zhongshan District, 104 Taipei, Taiwan)

台北神旺大飯店(SAN WANT HOTEL): 106 台北市大安區忠孝東路四段 172號 (No. 172, Section 4,

Zhong Xiao East Road, Da'an District, 106 Taipei, Taiwan)

Page 51: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 51 -

APCBEES Forthcoming Conferences

http://www.cbees.org/events/

CONFERENCE INFORMATION PUBLICATION

January 21-23, 2017, Bangkok, Thailand

ICBBB 2017

2017 7th International Conference on

Bioscience, Biochemistry and

Bioinformatics (ICBBB 2017)

http://www.icbbb.org/

International Conference Proceedings Series by

ACM (Indexing: Ei Compendex and Scopus )

February 08-10, 2017, Frankfurt, Germany

ICCCP 2017

2017 7th International Conference on

Chemistry and Chemical Process (ICCCP

2017)

http://www.icccp.org/

International Journal of Chemical Engineering and

Applications (IJCEA ISSN: 2010-0221)

February 25-27, 2017, Hanoi, Vietnam

ICFES 2017

2017 3rd International Conference on Food

and Environmental Sciences (ICFES 2017))

http://www.icfes.org/

International Journal of Food Engineering (IJFE,

ISSN:2301-3664)

or

International Proceedings of Chemical, Biological

and Environmental Engineering (IPCBEE, ISSN:

2010-4618)

March 13-15, 2017, Prague, Czech Republic

ICCBS 2017

2017 4th International Conference on

Chemical and Biological Sciences

(ICCBS 2017)

http://www.iccbs.org/

International Journal of Chemical Engineering and

Applications (IJCEA, ISSN:2010-0221)

or

International Journal of Bioscience, Biochemistry

and Bioinformatics (IJBBB, ISSN: 2010-3638)

or

International Journal of Pharma Medicine and

Biological Sciences (IJPMBS, ISSN: 2278-5221)

Page 52: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 52 -

March 28-30, 2017, Osaka, Japan

ICCFE 2017

2017 4th International Conference on

Chemical and Food Engineering (ICCFE

2017)

http://www.iccfe.org/

International Journal of Chemical Engineering and

Applications (IJCEA ISSN: 2010-0221)

or

International Journal of Food Engineering (IJFE,

ISSN: 2301-3664),

April 11-13, 2017, Seoul, South Korea

ICPPS 2017

2017 2nd International Conference on

Pharmacy and Pharmaceutical Science

(ICPPS 2017)

http://www.icpps.org/

International Journal of Pharmacy and

Pharmaceutical Sciences (IJPPS, ISSN 0975 - 1491)

(Indexing: Scopus)

April 21-23, 2017, Hong Kong

ICBET 2017

2017 7th International Conference on

Biomedical Engineering and Technology

(ICBET 2017)

http://www.icbet.org/

International Journal of Pharma Medicine and

Biological Sciences (IJPMBS, ISSN: 2278-5221)

or

International Journal of Bioscience, Biochemistry

and Bioinformatics (IJBBB, ISSN: 2010-3638)

April 24-26, 2017, Kuala Lumpur, Malaysia

ICFEB 2017

2017 8th International Conference on Food

Engineering and Biotechnology (ICFEB

2017)

http://www.icfeb.org/

International Journal of Food Engineering (IJFE,

ISSN: 2301-3664)

or

International Journal of Life Sciences

Biotechnology and Pharma Research (IJLBPR,

ISSN:2250-3137)

May 10-12, 2017, Budapest, Hungary

ICFAE 2017

2017 3rd International Conference on Food

and Agricultural Engineering (ICFAE 2017)

http://www.icfae.org/

Journal of Advanced Agricultural Technologies

(JOAAT, ISSN:2301-3737)

or

International Journal of Food Engineering (IJFE,

ISSN: 2301-3664)

Page 53: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 53 -

May 25-27, 2017, Beijing, China

ICCPE 2017

2017 6th International Conference on

Chemical and Process Engineering (ICCPE

2017)

http://www.iccpe.org/

International Journal of Chemical Engineering and

Applications (IJCEA, ISSN: 2010-0221)

Welcome to participate in APCBEES upcoming conferences.

Good news! To join in APCBEES member is free now. If you are interested, please check the

information on the website: http://www.cbees.org/membership/. Any question regarding to

membership, please feel free to contact [email protected].

Page 54: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 54 -

Note

Page 55: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 55 -

Note

Page 56: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 56 -

Note

Page 57: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 57 -

Feedback Information (Please fill this form and return it to conference specialist during the conference days.)

Personal Information

Conference Name and Paper

ID

Full Name

E-mail Address

Area of Research

Affiliation

Please indicate your overall satisfaction with this conference with “”

Very

Satisfied

Somewhat

Satisfied

Neutral Somewhat

Dissatisfied

Very

Dissatisfied

Conference Content

Presentation and Paper Value

Registration Process

Venue

Food and Beverage

Are You A Member of

APCBEES

YesNo

(If “No”, you may apply membership from

http://www.cbees.org/member.htm )

Do You Willing to Receive

APCBEES Future

Conferences Information Via

E-mail

YesNo

Where did you get the

conference information?

Would you please specify the

main reason for attending this

conference?

Did the conference fulfill your

reason for attending?

Yes– Absolutely Yes- But not to my full extent No

(If “No”, please tell us the main reason)

Page 58: 2016 APCBEES TAIPEI CONFERENCE ABSTRACTicabt.org/history/program-2016.pdf · 2016 APCBEES TAIPEI CONFERENCE - 6 - 2016 3rd International Conference on Biomedical and Bioinformatics

2016 APCBEES TAIPEI CONFERENCE

- 58 -

Would you please list the top

3 to 5 universities in your

city?

Other Field of Interest

Any Other

Suggestions/Comments

Thank you for taking time to participate in this conference evaluation. Your

comments will enable us to execute future conferences better and tailor them to

your needs!


Recommended