2019 Annual

Cancer Treatment-Related Adverse Events Symposium

2019

OCTOBER 25-26

ROCKEFELLER RESEARCH LABORATORIES 430 East 67th StreetNew York, NY

MSK COURSE DIRECTOR

Mario E. Lacouture, MDMember, Memorial HospitalDermatology Service

ORGANIZING COMMITTEE

Douglas Johnson, MDMember, Department of MedicineVanderbilt University Medical Center

Shari B. Goldfarb, MDAssistant Attending,Breast Medicine ServiceMemorial Sloan Kettering Cancer Center

Jarushka Naidoo, MDAssistant Professor of OncologyAttending, Lung and ImmunotherapySidney Kimmel Cancer CenterJohns Hopkins University

COURSE FACULTY

Tim Ahles, PhDPsychologist, Behavioral Medicine ServiceMemorial Sloan Kettering Cancer Center

Andrei Barasch,DDS, PhD, DABOMAssistant Professor, Dentistry in Medicine Weill Cornell Medical Center

Laura Cappelli, MD MHSAssistant Professor of Medicine, Department of Medicine, Division of Clinical and Molecular RheumatologyJohns Hopkins Medical Center

Maria Castells, MDAssociate Professor, Harvard Medical SchoolDivision of Rheumatology, Immunology, and AllergyBrigham and Women’s Hospital

Kathryn Ciccolini, AGACNP-BCHematology/Oncology ServiceMount Sinai Hospital/ Ruttenberg Cancer Center

Robert Daly, MD, MBAAttending, Lung ServiceMemorial Sloan Kettering Cancer Center

James Flory, MDAssistant Professor, Department of Healthcare Policy and Research Weill Cornell Medical CollegeAssistant Attending, Endocrine ServiceMemorial Sloan Kettering Cancer Center

Monica Girotra, MDAssociate Clinical Member, Endocrinology Memorial Sloan Kettering Cancer CenterWeill Cornell Medical College

Ilya Glezerman, MDClinical Director, Nephrology Service Memorial Sloan Kettering Cancer Center

Richard J. Gralla, MDProfessor, Department of Medicine (Oncology)Director of Oncology Research for the North Bronx Healthcare NetworkAlbert Einstein College of Medicine

Korey Jaben, MDAssistant Attending, Ophthalmic Oncology ServiceAssistant Professor, Department of Healthcare Policy and ResearchMemorial Sloan Kettering Cancer Center

Dorothy Keefe, MDCEO Cancer Australia Clinical ProfessorUniversity of AdelaideAustralia

Bernice Kwong, MDClinical Associate Professor, Dermatology ServiceDirector, Supportive Dermato-Oncology ProgramDirector, Inpatient Dermatology Consult ServiceStanford Cancer Center

Charles Loprinzi, MDConsultant, Division of Medical Oncology, Department of OncologyMayo Clinic

Jun Mao, MDChief, Integrative Medicine ServiceMemorial Sloan Kettering Cancer Center

Javid Moslehi, MDDirector, Cardio-OncologyAssistant Professor of Medicine, Cardiovascular Service Vanderbilt University Medical Center

John Probasco MDMedical Director, Inpatient General Neurology ServiceAssociate Professor of NeurologyJohns Hopkins Hospital

Vickie Shannon, MDMember, PsychiatryProfessor, Department of Pulmonary Medicine,Division of Internal MedicineMD Anderson Cancer CenterDirector of Pulmonary Rehabilitation MD Anderson Cancer Center

Gerald Soff, MDChief, Hematology Service Co-Director, Hematology-Oncology FellowshipMemorial Sloan Kettering Cancer CenterProfessor of Clinical MedicineWeill Cornell Medical College

Anthony Yu, MDAssistant Attending, Cardiology Service Memorial Sloan Kettering Cancer Center

Michael L. Dougan, MD, PhDDirector of the Immunotherapy Mucosal

Inflammation Program, Division of GastroenterologyMassachusetts General Hospital

mskcc.org/AdverseEvents

OVERVIEW

SYMPOSIUM HIGHLIGHTS

• Therapy-related adverse events will affect the majority of cancer patients, resulting in increased cost, inconsistent dosing, and decreased quality of life.

• With increased survival and patients living longer on therapy, adverse events affecting quality of life and clinical outcome command attention.

• Lectures focused on immune-related adverse events will describe clinical presentation, diagnosis, and management strategies for the oncology healthcare provider.

• Up-to-date information will be presented on adverse event mechanisms and management from specialists in the most commonly affected organ systems.

• Practical strategies to maintain patients’ quality of life and dose intensity will be highlighted for the most frequently occurring events.

Live Simulcast Available - We are pleased to offer a live simulcast option for this symposium. CME and ABIM MOC credit is offered for the live simulcast.

Endorsed by the Multinational Association of Supportive Care in Cancer

Systemic anticancer therapies (cytotoxic chemotherapies, targeted therapies, immunotherapies) have resulted in remarkable improvements in patient survival. Despite this remarkable success, the majority of patients will develop toxicities of various organ systems, which may impact overall health and activities of daily living, resulting in inconsistent antineoplastic therapy, all of which may affect clinical outcome. Therefore, prevention and management of untoward events is critical for the maintenance of quality of life and the optimization of anticancer therapies.

Educational Objectives

• Recognize the clinical presentation and impact on quality of life of treatment-related adverse events

• Understand mechanisms and interventions to prevent and treat adverse events

• Discuss procedures and clinical tools to assess treatment-related toxicities in cancer patients

Target Audience

The target audience for this symposium includes MDs, PAs, NPs, RNs, Pharmacists, and other professionals treating cancer patients and their associated symptoms.

Registration & Breakfast 8:00 am

Cytotoxic and Targeted Therapies – Session IMODERATOR: Shari Goldfarb, MD

Welcome and Introduction: Importance of Adverse Events Mario E. Lacouture, MD

8:30 am

Keynote Lecture Menopausal Symptom Management in Breast Cancer Survivors Charles Loprinzi, MD

8:45 am

Nausea and Vomiting Richard J. Gralla, MD

9:15 am

Integrative Medicine in Oncology Jun Mao, MD

9:45 am

Break 10:15 am

VTE and Treatment-Related Coagulopathies Gerald A. Soff, MD

10:45 am

Cardiac ToxicitiesAnthony Yu, MD

11:15 am

Sexual Dysfunction in Women Shari Goldfarb, MD

11:45 am

Lunch 12:10 pm

Cytotoxic and Targeted Therapies – Session IIMODERATOR: Mario Lacouture, MD

Misery Loves Company AE Symptom Clusters Robert Daly, MD

1:00 pm

Hypersensitivity ReactionsMariana Castells, MD, PhD

1:30 pm

Ocular ToxicitiesKorey Jaben, MD

2:00 pm

Break 2:30 pm

Mucositis and Stomatitis Andrei Barasch, DDS, PhD, DABOM

3:00 pm

Treatment-Related Psychiatric and Cognitive Disorders Tim Ahles, PhD

3:30 pm

Dermatologic Toxicities from Cytotoxic and Targeted Agents Bernice Kwong, MD

4:00 pm

Immune Related Endocrine ToxicitiesMonica Girotra, MD

4:30 pm

Adverse Event Triage and Acute Evaluations Kathryn Ciccolini, AGANCP-BC, NP

5:00 pm

Panel DiscussionAll Faculty

5:15 pm

Adjourn 5:30 pm

Networking Reception Join the course faculty for a networking reception from 5:30 - 6:30 pm at Rockefeller Research Laboratories. Hors d’oeuvres and refreshments will be served.

Join the conversation:#MSKadverseeventsCME

@MSKCME

OCTOBER 25FRIDAY

OCTOBER 26SATURDAY

mskcc.org/AdverseEvents

Breakfast 7:30 am

Immunotherapy-Related Adverse Events – Session IMODERATOR: Jarushka Naidoo, MBBCh

Welcome and Introduction: Multidisciplinary AE ManagementJarushka Naidoo, MBBCh

8:00 am

Immune-Related GI Adverse Events Michael L. Dougan, MD, PhD

8:25 am

Keynote Lecture Research on GI Toxicities, Past, Present and Future Dorothy Keefe, MD

8:50 am

Immune-Related Pulmonary Events Vickie Shannon, MD

9:20 am

Immune-Related Cardiac Events Javid Moslehi, MD

9:50 am

Panel Discussion All Faculty

10:15 am

Break 10:30 am

Immunotherapy-Related Adverse Events – Session IIMODERATOR: Douglas Johnson, MD

Severe Immune-Related Adverse Events Douglas Johnson, MD

11:00 am

Immune-Related Adverse Events - KidneyIlya Glezerman, MD

11:25 am

Immune-Related Neurologic Events John Probasco, MD

11:50 am

Immune-Related Dermatologic Toxicities Mario E. Lacouture, MD

12:15 pm

Immune-Related Rheumatic DisordersLaura Cappelli, MD MHS

12:35 pm

Hyperglycemia and Cushing Disease James Flory, MD

12:50 pm

Panel Discussion All Faculty

1:15 pm

Closing Remarks Mario Lacouture, MD

1:30 pm

Adjourn 1:45 pm

Live Simulcast Available We are pleased to offer a live simulcast option for this symposium. CME and ABIM MOC credit is offered for the live simulcast.

Registration Fees Early* General

Physicians (MDs, PhDs and DOs) $450 $500

Advanced Practice Providers $450 $500

Pharmacists, Nurses and Other Healthcare Providers $300 $350

Fellows and Residents $250 $300

Live Simulcast $650 $700

Industry Professionals** $825 $875

*Early registration rates expire September 13, 2019.**Industry professionals may attend MSK CME activities for their own education. Marketing, sales, and promotion of products and services is strictly prohibited at MSK CME activities.

Register online:

mskcc.org/AdverseEventsCourse registration includes continental breakfast, lunch, and refreshment breaks. Please contact cme@mskcc.org at least one week prior to the course if you have any special dietary requests or require any specific accommodations.

• MSK CME offers a discounted rate for MSK Alumni, MSK Cancer Alliance and Cancer Care Partners. If you are a member of one of these groups, please contact cme@mskcc.org for more information.

• MSK employee registration is complimentary. However, you must complete course registration in order to attend this course.

Symposium Location Memorial Sloan Kettering Cancer Center Rockefeller Research Laboratories430 East 67th StreetNew York, NY

AccommodationsMSK has negotiated special rates and amenities at select hotels in Manhattan. For information on hotels in the vicinity of MSK with discounted rates, visit: mskcc.org/cme

ContactMemorial Sloan Kettering Cancer CenterOffice of Continuing Medical Educationw: mskcc.org/cmee: cme@mskcc.org

Memorial Sloan Kettering Cancer Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

AMA Credit Designation StatementMemorial Sloan Kettering Cancer Center designates this live activity for a maximum of 12.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ABIM MOC Recognition StatementSuccessful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 12.50 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Faculty DisclosureIt is the policy of MSK to make every effort to insure balance, independence,objectivity, and scientific rigor in all continuing medical education activitieswhich it provides as an ACCME accredited provider. In accordance with ACCMEguidelines and standards, all faculty participating in an activity provided by MSKare expected to disclose any significant financial interest or other relationshipwith the manufacturer(s) of any commercial product(s) and/or provider(s) ofcommercial services which are discussed by the faculty members in aneducational presentation. As required by the ACCME, when an unlabeled use of a commercial product or an investigational use not yet approved for any purpose is discussed during an educational activity, MSK requires the speaker to disclose that the product is not labeled for the use under discussion or that the product is still investigational.

ACCREDITATION

REGISTRATION ROCKEFELLER RESEARCH LABORATORIES

2019 Annual

Cancer Treatment-Related Adverse Events Symposium