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25 DIVISION OF CARDIOLOGY FACULTY LISTING

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25 DIVISION OF CARDIOLOGY FACULTY LISTING Robert H. Beekman, III, M.D., Division Director, Professor D. Woodrow Benson, M.D., Ph.D., Professor, Director Cardiovascular Genetics Randal P. Claytor, Adjunct Associate Professor Linda Cripe, M.D., Assistant Professor Stephen Daniels, M.D., Ph.D., Professor, Director, Preventive Cardiology, Associate Chair, Department of Pediatrics Catherine Dent, M.D., Assistant Professor Michael Epstein, M.D., Assistant Professor Jeanne James, M.D., Research Assistant Professor Thomas Kimball, M.D., Professor, Director, Echocardiography Timothy Knilans, M.D., Associate Professor, Director, Electrophysiology Richard Meyer, M.D., Professor Erik Michelfelder, M.D., Assistant Professor John Morrison, Ph.D., Research Associate Professor David Nelson, M.D., Ph.D., Assistant Professor, Co-director, Cardiac ICU Steven Schwartz, M.D., Assistant Professor, Co-director, Cardiac ICU David Shim, M.D., Assistant Professor, Director, Cardiac Cath Lab Robert Spicer, M.D., Professor, Medical Director of Heart Transplant Program Karen Uzark, R.N., Ph.D., Associate Professor, Director, Cardiac Process Improvement and Clinical Effectiveness Kathy Wright, D.V.M., Research Assistant Professor Left to right: (1 st row) T. Knilans, R. Beekman, J. James, (2 nd row) M. Epstein, R. Meyer, C. Dent, J. Morrison
Transcript

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DIVISION OF CARDIOLOGY

FACULTY LISTING

Robert H. Beekman, III, M.D., Division Director, ProfessorD. Woodrow Benson, M.D., Ph.D., Professor, Director Cardiovascular GeneticsRandal P. Claytor, Adjunct Associate ProfessorLinda Cripe, M.D., Assistant ProfessorStephen Daniels, M.D., Ph.D., Professor, Director, Preventive Cardiology, Associate Chair, Department of PediatricsCatherine Dent, M.D., Assistant ProfessorMichael Epstein, M.D., Assistant ProfessorJeanne James, M.D., Research Assistant ProfessorThomas Kimball, M.D., Professor, Director, EchocardiographyTimothy Knilans, M.D., Associate Professor, Director, ElectrophysiologyRichard Meyer, M.D., ProfessorErik Michelfelder, M.D., Assistant ProfessorJohn Morrison, Ph.D., Research Associate ProfessorDavid Nelson, M.D., Ph.D., Assistant Professor, Co-director, Cardiac ICUSteven Schwartz, M.D., Assistant Professor, Co-director, Cardiac ICUDavid Shim, M.D., Assistant Professor, Director, Cardiac Cath LabRobert Spicer, M.D., Professor, Medical Director of Heart Transplant ProgramKaren Uzark, R.N., Ph.D., Associate Professor, Director, Cardiac Process Improvement

and Clinical EffectivenessKathy Wright, D.V.M., Research Assistant Professor

Left to right: (1st row) T. Knilans, R. Beekman, J. James, (2nd row) M. Epstein, R. Meyer, C. Dent, J. Morrison

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OVERVIEW

The Division of Cardiology has three fundamental missions: 1) To advance pediatriccardiovascular medicine through clinical and laboratory research; 2) To train futureleaders in academic pediatric cardiology; and 3) To provide outstanding care to patientswith congenital or acquired cardiovascular disease, from the fetus through the youngadult.

The division supports active research programs in the clinical and basic sciences.Clinical research is underway in the key subspecialties of pediatric cardiology includingcardiac critical care, echocardiography, electrophysiology, genetic cardiology, heartfailure, interventional cardiology, outcomes research and preventive cardiology. Basicscience research is strengthened through an active collaboration with the Division ofMolecular Cardiovascular Biology. Investigations are underway to elucidate themolecular and genetic aspects of pediatric cardiovascular disease. Several facultymembers have joint appointments in Cardiology and Molecular Cardiovascular Biologyto facilitate the translation of basic science to the clinical arena and patient care.

The goal of the pediatric cardiology fellowship program is to provide excellent trainingexperiences to develop future academic leaders in the field of pediatric cardiology. Thecore three-year fellowship includes approximately 20 months of intense clinical rotationsto provide each fellow with an in-depth experience in general and subspecialty pediatriccardiology. Approximately 12-14 months are available to each fellow to pursue clinicalor basic research interests. The second year of fellowship begins with a two monthprotected “research launch” rotation designed to enable each fellow to get a rapideffective start on an academic career. During this rotation each fellow meets with theCardiology Research Council to ensure that each fellow receives strong guidance andmentoring in academic cardiology and career development. During the past two years, asa result of this new “research launch” experience, approximately 50% of our fellows havereceived American Heart Association fellowship grant awards. The fellowshipexperience also includes a large number of didactic teaching sessions, including a threemonth core curriculum lecture series which begins each July.

The Division of Cardiology provides comprehensive diagnostic and therapeutic care, onan inpatient and outpatient basis, for the fetus, newborn, child and young adult withcongenital or acquired cardiovascular disease. The Fetal Cardiology Program is amultidisciplinary approach to diagnostic and therapeutic planning for families whosefetus has suspected or identified congenital heart disease. The Inpatient CardiologyService consists of two pediatric interns, a cardiology fellow and attending faculty whotogether provide daily inpatient and consultative care throughout the medical center. TheCardiac Intensive Care Unit provides state-of-the-art care for patients with the mostcomplex congenital or acquired cardiovascular disease. The cardiac ICU team consists ofa cardiology fellow, cardiac intensivist, and well-trained cardiac-focused intensive carenurses. There is close collaboration with the Division of Critical Care Medicine, andthree of our cardiologists are also fully trained in pediatric critical care. Cutting edgeinpatient and outpatient care is also provided by the division’s subspecialty cardiology

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programs in echocardiography, electrophysiology, cardiac catheterization andintervention, genetic cardiology, heart failure and cardiac transplantation, and preventivecardiology. Twenty-five cardiology clinics are held at Cincinnati Children’s HospitalMedical Center weekly, and the division staffs approximately 150 satellite cardiologyclinics annually throughout the region.

HIGHLIGHTS

The division’s research activities continued to be strong during the past year. ThePreventive Cardiology Research Program led by Stephen Daniels, M.D., Ph.D., continuedto be highly successful. Substantial NIH grant funding supported investigation of theeffects of race on blood pressure in adolescent females, the effects of visceral adiposityon cardiovascular disease risk in females, and the epidemiology of body mass reboundfollowing weight loss. The Cardiovascular Genetics Research Program led by WoodyBenson, M.D., Ph.D., continued its pioneering work to uncover the genetic origins ofhuman congenital heart disease. Dr. Benson received NIH funding to support studies ofthe genetic and molecular origins of cardiovascular disease, and the genetic origin of AVconduction abnormalities in children. Research activity continued at a very high level inthe pediatric echocardiography program. Led by Tom Kimball, M.D., this program hasachieved national stature as a leader in the non-invasive assessment of ventricularfunction in children with acquired and congenital cardiovascular disease.

The cardiology clinical programs continued to provide a very high level care to childrenand young adults with the most complex cardiovascular disease. The Heart Center, amultidisciplinary clinical program unifying the efforts of cardiology, cardiothoracicsurgery and cardiac-focused nursing and patient services, provided the mechanism tosuccessfully achieve the goal of clinical excellence. This past year is particularly notablefor a high level of planning activity for near term creative growth and development of ourclinical programs. These include: 1) The conversion of our echo lab to an entirely digitalinfrastructure and network; 2) The establishment of a cardiology information network tomanage patient care and clinical research information digitally; 3) The expansion of ourcardiac catheterization program to two new all digital labs, to include a digital cardiacangiography network and archiving system; and 4) planning for a new cardiac inpatientward and stepdown unit to be housed in the new patient care building A. Importantfunctional changes will include incorporation of the cardiac ward nursing team into theHeart Center Program, and integration of the cardiac catheterization program into theinpatient ward facility. All of these clinical enhancements are expected to come on lineover the next 12 months.

CLINICAL DATA

Patient Encounters:Inpatient 2,568Outpatient 8,395

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TRAINING

Terrence Chun, M.D. PL V Cedars-Sinai Medical CenterWilliam Border, M.D. PL VI Baystate Medical CenterDavid Cooper, M.D. PL VI University of South FloridaDaniel Gruenstein, M.D. PL VI Children’s Hospital Medical CenterHolly Ippisch, M.D. PL IV Loma Linda University Children’sGerald Johnson, M.D. PL V Vanderbilt University Medical Ctr.Larry Markham, M.D. PL IV Albany Medical CenterChristopher McDermott, M.D. PL IV Univ. of Arkansas, Medical SciencesMark Zilberman, M.D. PL V Indiana University Medical Center

GRANTS, CONTRACTS & INDUSTRY AGREEMENTS

Grant and Contract Awards

Benson, W.

Genetic Mechanisms of Cardiac Disease in the Young

National Institutes of Health

K24 HL69712 06/15/01 - 05/31/06 $122,526/$612,630 Benson, W.

Genetic Origin of Structural and Functional Defects of Atrioventricular

Conduction in Humans

National Institutes of Health (Medical University of South Carolina subcontract)

P01 HD39946 06/28/01 – 04/30/06 $85,491/$440,658Benson, W.

Molecular Determinants of Pediatric Heart Disease

National Institutes of Health (Washington University subcontract)

P50 HL61006 03/01/01 - 12/31/03 $154,470/$439,487Border, W.

The Prevelance and Determinants of LV Diastolic Function in Hyoertensive

Children

American Heart Associate – Ohio Valley Affiliate

PF 0120186B 07/01/01 - 06/30/02 $37,000/$76,000

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Cooper, D.

Ventricular Resynchronization in Patients with Right Ventricular

Dysfunction and Abnormal Conduction after Congenital Heart Surgery

American Heart Associate – Ohio Valley Affiliate

PF 0120297B 07/01/01 - 06/30/02 $37,000/$76,000Daniels, S.

Visceral Adiposity and CVD Risk in Women

National Institutes of Health

R01 HL66430-02 03/05/01 – 02/28/06 $487,263/$2,251,463Daniels, S.

Fibromyalgia and TMD in Young Women-Multiracial Study

National Institutes of Health (University of California San Francisco subcontract)

R01 DE13487 09/25/99 – 08/31/02 $20,684/$103,622

Daniels, S.

The Epidemiology of Body Mass Index Rebound

National Institutes of Health

R01 HL64022 08/17/01 – 07/31/05 $465,926/$2,317,851

Daniels, S.

Genetic Epidemiology of Energy Metabolism in Black Girls

National Institutes of Health (University of Pittsburgh subcontract)

R01 HL66070 05/01/01 – 04/30/05 $172,686/$676,944

Morrison, J.

Longitudinal LDL-C Studies in Black and White Families

National Institutes of Health

R01 HL62394 07/01/00 – 06/30/04 $413,123/$1,674,525

Schroeder, V.

Effect of Methylpredrisolone on the Inflammatory Response FollowingCardiopulmonary BypassAmerican Heart Association - Ohio Affiliate, Inc.

0020320B 07/01/00 – 06/30/02 $35,000/$70,000

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Wright, K.

Developmental Changes in Chamber-Specific K+ Channels

American Heart Association - Ohio Affiliate, Inc.

0060335B 07/01/00 – 06/30/02 $35,000/$70,000

Current Year Direct $2,344,590

Industry ContractsDaniels, S.

Bristol-Myers Squibb Company $11,669

Daniels, S.

Knoll Pharmaceuticals $61,201Daniels, S.

Merck and Company, Inc. $9,322Daniels, S.

Warner-Lambert Company $8,640Epstein, M.

Baxter Healthcare Corporation $12,003

Knilans, T.

Wyeth-Ayerst Pharmaceuticals, Inc. $4,619

Nelson, D.

Baxter Healthcare Corporation $3,662Schwartz, S.

Sanofi-Synthelabo Inc. $5,544Shim, D.

General Electric $3,811Wright, K.

Procter and Gamble $4,935

Current Year Direct Receipts $125,406

TOTAL $2,469,996

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PUBLICATIONS

1. Moore JWM, Beekman RH, 3rd, Case CL, Danford DA, Klitzner TS, Mee RBB,Newberger JW, Washington RL. Guidelines for pediatric cardiovascular centers.Pediatrics 2002;109(3):544-9.

2. Mendelsohn A, Shim D, Beekman RH, 3rd. Catheter interventions in congenitalheart disease. In: Topol EJ, Califf RM, editors. Textbook of cardiovascularmedicine. 2nd ed ed. Philadelphia: Lippincott Williams & Wilkins; 2002.

3. Goldmuntz E, Geiger E, Benson DW . NKX2.5 mutations in patients withtetralogy of fallot. Circulation 2001;104(21):2565-8.

4. Wang DW, Viswanathan PC, Balser JR, George AL, Jr., Benson DW. Clinical,genetic, and biophysical characterization of SCN5A mutations associated withatrioventricular conduction block. Circulation 2002;105(3):341-6.

5. Arad M, Benson DW, Perez-Atayde AR, McKenna WJ, Sparks EA, Kanter RJ,McGarry K, Seidman JG, Seidman CE. Constitutively active AMP kinasemutations cause glycogen storage disease mimicking hypertrophiccardiomyopathy. J Clin Invest 2002;109(3):357-62.

6. Benson DW. Genetic basis of distrubances of cardiac rhythm and conduction. In:Walsh EP, Saul JP, Triedman JK, editors. Cardiac arrhythmias in children andyoung adults with congenital heart disease. Philadelphia: Lippincott Williams &Wilkins; 2001. p. 23-32.

7. Benson DW , Law I. The electrocardiogram: preliminary interpretation. In:Finberg L, Kleinman RE, editors. Saunders manual of pediatric practice. 2nd eded. Philadelphia: W.B. Saunders; 2002. p. 696-699.

8. Claytor RP. Characteristics of excellent coaching. In: Patrick K, United States.Maternal and Child Health Bureau, National Center for Education in Maternal andChild Health (U.S.), editors. Bright futures in practice : physical activity.Arlington, VA: National Center for Education in Maternal and Child Health;2001. p. 196-198.

9. Kimm SY, Glynn NW, Aston CE, Poehlman ET, Daniels SR. Effects of race,cigarette smoking, and use of contraceptive medications on resting energyexpenditure in young women. Am J Epidemiol 2001;154(8):718-24.

10. Kay JD, Sinaiko AR, Daniels S R. Pediatric hypertension. Am Heart J2001;142(3):422-32.

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11. de Simone G, Devereux RB, Kimball TR, Roman MJ, Palmieri V, Celentano A,Daniels SR. Relation of heart rate to left ventricular dimensions in normotensive,normal-weight children, adolescents and adults. Ital Heart J 2001;2(8):599-604.

12. Daniels SR. Cardiovascular disease risk factors and atherosclerosis in childrenand adolescents. Curr Atheroscler Rep 2001;3(6):479-85.

13. Daniels SR. Repair of coarctation of the aorta and hypertension: does age matter?Lancet 2001;358(9276):89.

14. Sinaiko AR, Daniels SR. The use of short-acting nifedipine in children withhypertension: another example of the need for comprehensive drug testing inchildren. J Pediatr 2001;139(1):7-9.

15. Daniels SR. Cardiovascular sequelae of childhood hypertension. Am J Hypertens2002;15(2 Pt 2):61S-63S.

16. Kimm SY, Glynn NW, Aston CE, Damcott CM, Poehlman ET, Daniels SR,Ferrell RE. Racial differences in the relation between uncoupling protein genesand resting energy expenditure. Am J Clin Nutr 2002;75(4):714-9.

17. Amin RS, Kimball TR, Bean JA, Jeffries JL, Willging JP, Cotton RT, Witt SA,Glascock BJ, Daniels SR. Left Ventricular Hypertrophy and AbnormalVentricular Geometry in Children and Adolescents with Obstructive Sleep Apnea.Am J Respir Crit Care Med 2002;165(10):1395-1399.

18. Dent CL, Bowman AW, Scott MJ, Allen JS, Lisauskas JB, Janif M, Wickline SA,Kovacs SJ. Echocardiographic characterization of fundamental mechanisms ofabnormal diastolic filling in diabetic rats with a parameterized diastolic fillingformalism. J Am Soc Echocardiogr 2001;14(12):1166-72.

19. Dent CL. Pulmonary hypertension in children. In: Burg FD, Gellis SS, KaganBM, editors. Gellis & Kagan's current pediatric therapy 17. 17[th ] ed.Philadelphia: Saunders; 2002. p. 553-556.

20. Love BA, Barrett KS, Alexander ME, Bevilacqua LM, Epstein MR, TriedmanJK, Walsh EP, Berul CI. Supraventricular arrhythmias in children and youngadults with implantable cardioverter defibrillators. J Cardiovasc Electrophysiol2001;12(10):1097-101.

21. Sohal DS, Nghiem M, Crackower MA, Witt SA, Kimball TR , Tymitz KM,Penninger JM, Molkentin JD. Temporally regulated and tissue-specific genemanipulations in the adult and embryonic heart using a tamoxifen-inducible Creprotein. Circ Res 2001;89(1):20-5.

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22. Mitsnefes MM, Schwartz SM, Daniels SR, Kimball TR, Khoury P, Strife CF.Changes in left ventricular mass index in children and adolescents after renaltransplantation. Pediatr Transplant 2001;5(4):279-84.

23. Silber JH, Cnaan A, Clark BJ, Paridon SM, Chin AJ, Rychik J, Hogarty AN,Cohen MI, Barber G, Rutkowsky M, Kimball TR, Delaat C, Steinherz LJ, ZhaoH, Tartaglione MR. Design and baseline characteristics for the ACE InhibitorAfter Anthracycline (AAA) study of cardiac dysfunction in long-term pediatriccancer survivors. Am Heart J 2001;142(4):577-85.

24. Schultz Jel J, Witt SA, Glascock BJ, Nieman ML, Reiser PJ, Nix SL, KimballTR, Doetschman T. TGF-beta1 mediates the hypertrophic cardiomyocyte growthinduced by angiotensin II. J Clin Invest 2002;109(6):787-96.

25. Bueno OF, Wilkins BJ, Tymitz KM, Glascock BJ, Kimball TR, Lorenz JN,Molkentin JD. Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice. Proc Natl Acad Sci U S A 2002;99(7):4586-91.

26. Steinberg LA, Knilans TK. Costs and utility of tests in the evaluation of thepediatric patients with syncope. Prog Pediatr Cardiol. 2001;13(2):139-149.

27. Wenstrup RJ, Meyer RA , Lyle JS, Hoechstetter L, Rose PS, Levy HP,Francomano CA. Prevalence of aortic root dilation in the Ehlers-Danlossyndrome. Genet Med 2002;4(3):112-7.

28. Michel fe lder EC , Khoury P, Witt SA, Glascock BJ, Kimball TR.Noncircumferential myofiber function: impact on early diastolic filling inchildren. J Am Soc Echocardiogr 2001;14(11):1065-9.

29. Michelfelder EC, Shim D. Kawasaki Disease: Current Therapeutic Perspectives.2002;4(4):341-350.

30. Michelfelder EC, Kimball TR, Pearl JM, Manning PB, Beekman RH, 3rd. Effectof superior cavopulmonary anastomosis on the rate of tricuspid annulus dilation inhypoplastic left heart syndrome. Am J Cardiol 2002;89(1):96-8.

31. Morrison JA, Sprecher DL, Biro FM, Apperson-Hansen C, Dipaola LM. Serumtestosterone associates with lower high-density lipoprotein cholesterol in blackand white males, 10 to 15 years of age, through lowered apolipoprotein AI andAII concentrations. Metabolism 2002;51(4):432-7.

32. Morrison JA , Cottingham EM, Barton BA. Metformin for weight loss inpediatric patients taking psychotropic drugs. Am J Psychiatry 2002;159(4):655-7.

33. Shore S, Nelson DP, Pearl JM, Manning PB, Wong H, Shanley TP, Keyser T,Schwartz SM. Usefulness of corticosteroid therapy in decreasing epinephrine

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requirements in critically ill infants with congenital heart disease. Am J Cardiol2001;88(5):591-4.

34. Schwartz SM, Duffy JY, Pearl JM, Nelson DP. Cellular and molecular aspects ofmyocardial dysfunction. Crit Care Med 2001;29(10 Suppl):S214-9.

35. Nelson DP, Wechsler SB, Miura T, Stagg A, Newburger JW, Mayer JE, Jr.,Neufeld EJ. Myocardial immediate early gene activation after cardiopulmonarybypass with cardiac ischemia-reperfusion. Ann Thorac Surg 2002;73(1):156-62.

36. Pearl JM, Nelson D P, Schwartz SM, Manning PB. First-stage palliation forhypoplastic left heart syndrome in the twenty-first century. Ann Thorac Surg2002;73(1):331-9; discussion 339-40.

37. Pearl JM, Nelson DP, Raake JL, Manning PB, Schwartz SM, Koons L, ShanleyTP, Wong HR, Duffy JY. Inhaled nitric oxide increases endothelin-1 levels: apotential cause of rebound pulmonary hypertension. Crit Care Med2002;30(1):89-93.

38. Hoffman TM, Wernovsky G, Atz AM, Bailey JM, Akbary A, Kocsis JF, NelsonDP, Chang AC, Kulik TJ, Spray TL, Wessel DL. Prophylactic intravenous use ofmilrinone after cardiac operation in pediatrics (PRIMACORP) study. ProphylacticIntravenous Use of Milrinone After Cardiac Operation in Pediatrics. Am Heart J2002;143(1):15-21.

39. Chu G, Carr AN, Young KB, Lester JW, Yatani A, Sanbe A, Colbert MC,Schwartz SM, Frank KF, Lampe PD, Robbins J, Molkentin JD, Kranias EG.Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenicmodel of heart failure. Cardiovasc Res 2002;54(1):105-16.

40. Varni JW, Seid M, Knight TS, Uzark K, Szer IS. The PedsQL 4.0 Generic CoreScales: sensitivity, responsiveness, and impact on clinical decision-making. JBehav Med 2002;25(2):175-93.

NATIONAL HONORS AND NATIONAL COMMITTEE PARTICIPATION

Beekman, RH: Pediatric Chair, Annual Scientific Sessions Program Committee,American College of Cardiology; Member, Congenital Heart Disease and PediatricCardiology Committee, American College of Cardiology; President, Society of PediatricCardiology, Training Program Directors; Member, Executive Committee, Section ofCardiology, American Academy of Pediatrics; Member, Board of Trustees, CincinnatiDivision of Ohio Affiliate, American Heart Association; Cardiac Standards Committee,Bureau for Children with Medical Handicaps, Ohio Department of Health; InauguralArthur J. Moss Lecturer Department of Pediatrics, UCLA School of Medicine, LosAngeles; Faculty, Pediatric Cardiac Catheterization Update 2002 ACC Heart House,

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Bethesda, MD; Pediatric Cardiology Highlights: ACC 2002 American College ofCardiology, Atlanta; Moderator: Controversies in Pediatric Cardiology, AmericanCollege of Cardiology, Atlanta; Co-Chair: Marfan Syndrome-State of the Art in 2002American College of Cardiology, Atlanta

Benson, DW: Best Doctors in America 2001-2002

Claytor, RP: Presentations, “Exercise Programming for a Pediatric Weight ManagementProgram: Children are Not Adults” American College of Sports Medicine, Health andFitness Summit, Las Vegas, NV; Aerobic fitness is related to fasting insulin in obesechildren, American College of Sports Medicine Annual Meetings, Baltimore, MD;Obese children exhibit similar improvements in submaximal cardiovascular function withand without improvements in Vo2max. American College of Sports Medicine AnnualMeetings, Baltimore, MD; Improved submaximal cardiovascular responses to exercise inchildren undergoing a weight management program, American College of SportsMedicine Annual Meetings, Baltimore, MD; Modified maximal cycle ergometer testprotocol for patients with univentricular hearts after Fontan palliation, American Collegeof Sports Medicine Annual Meetings, Baltimore, MD; Member in American College ofSports Medicine; MI west Region American College of Sports Medicine; Society ofBehavioral Medicine; North American Society of Pediatric Exercise Medicine; SteeringCommittee Member, Bright Futures in Practice: Physical Activity, Maternal and ChildHealth Bureau, Health Resources Services Administration, U.S. Department of Healthand Human Services; Research Grant Review Committee - Minority BiomedicalResearch Support Program; National Institutes of Health-National Institute of GeneralMedical Services (NIH-NIGMS); Manuscript Review - Journal Applied Physiology,Medicine and Science in Sport Exercise, Research Quarterly; Physiology and Behavior,and Journal of Pediatrics

Cripe, L: Member International Society of Heart and Lung Transplantation andAmerican Heart Association; Fellow, American Academy of Pediatrics; Family FriendlyCommittee, Children's Hospital Medical Center

Daniels, SR: Co-chair, Committee 1A, Southeast Consortium Research Peer ReviewCommittee, American Heart Association; Chairman, Atherosclerosis Hypertension andObesity in Youth (AHOY) Committee, American Heart Association; Chairman, ProgramCommittee for the Council on Nutrition, Physical Activity & Metabolism, AmericanHeart Association; Member of Steering Committee for Council on Nutrition, PhysicalActivity & Metabolism, American Heart Association; Member of Steering Committee forCouncil on Epidemiology, American Heart Association; Member, Population ScienceCommittee, American Heart Association; Reviewer of grant proposals, MedicalEducation Research Fund, National Board of Medical Examiners; USMLE Step 2Interdisciplinary Review Committee; USMLE Step 1 Biostatistics Task Force;Epidemiology and Disease Control Study Section-1, National Institutes of Health,Bethesda, MD; Special Emphasis Panel, Mentored Patient-Oriented Research CareerDevelopment Award (K23) and Midcareer Investigator Award in Patient-OrientedResearch (K24), National Heart, Lung, and Blood Institute, National Institutes of Health,

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Bethesda, MD; Member, NHLBI Task Force on Prevention of Cardiovascular Disease,National Institutes of Health, Bethesda, MD; Visiting Lecturer, Distinguished LectureSeries, The Cleveland Clinic Educational Foundation, "Integrated Cardiovascular HealthPromotion in Children"; Moderator, Abstract Session, Diabetes and CardiovascularDisease (Lipid/Nutrition) American Heart Association Scientific Sessions 2001,Anaheim, CA; Moderator, Abstract Session, Obesity and Cardiovascular Risk(Epidemiology) American Heart Association Scientific Sessions 2001, Anaheim, CA;Speaker, Obesity and its Complications in Adolescents, Prevention VIII: Obesity, AWorldwide Epidemic Related to Heart Disease and Stroke, American Heart Association

Epstein, M: Invited Speaker, “ICD Troubleshooting” in “Pacemakers and ICDs inChildren”, Mini Course at 22nd Annual Scientific Sessions of the North American Societyof Pacing and Electrophysiology (NASPE), Boston, MA; Member, Guidelines forTraining in Pediatric Clinical Cardiac Electrophysiology Subcommittee; Society forPediatric Cardiology Training Program Directors. Invited Speaker, “Prevention andTreatment of Arrhythmias after Fontan Surgery”, Brown-Bag Lunchtime Panel atAmerican College of Cardiology 51st Annual Scientific Sessions, Atlanta, GA; InvitedSpeaker, “ Single vs. Dual Chamber Pacing Selection” in “Device Therapy in the Smalland Young Patient”, Clinical Tutorial at 23rd Annual Scientific Sessions of the NorthAmerican Society of Pacing and Electrophysiology (NASPE), San Diego, CA; Member,Guidelines for Training in Pediatric Clinical Cardiac Electrophysiology Subcommittee;Society for Pediatric Cardiology Training Program Directors. Manuscript Reviews: TheAmerican Journal of Cardiology; The Journal of Cardiovascular Electrophysiology;Journal of Pediatrics

Kimball, T: Abstract Reviewer, American Heart Association Annual Scientific Sessions;Reviewer, Intersocietal Commission for the Accreditation of EchocardiographyLaboratories; Member, Sonographer Training and Education Committee, AmericanSociety of Echocardiography; Chairperson, Council of Pediatric Echocardiography,American Society of Echocardiography; Member, American College ofCardiology/American Heart Association/American Society of EchocardiographyCommittee to Update Guidelines for the Clinical Application of Echocardiography; PeerReview Grant Committee, Ohio and Southeastern Affiliates, American HeartAssociation; Member, Task Force on Training Pediatric Noninvasive Cardiac Imaging,Society of Pediatric Cardiology Training Program Directors; Member, American Societyof Echocardiography Board of Directors; Member, Guidelines and Standards Committee,American Society of Echocardiography; Member, Nominating, Bylaws and EthicsCommittee, American Society of Echocardiography

Knilans, T: Drug Use Evaluation Subcommittee, Children's Hospital Medical CenterMember & Co-Chair; Medication Safety Subcommittee, Children’s Hospital MedicalCenter; Pharmacy and Therapeutic Committee, Children’s Hospital Medical Center;Reviewer for Journal of Pediatrics, Journal of American College of Cardiology,Circulation; Memberships - Academy of Medicine, Cincinnati, Ohio; AmericanAssociation for the Advancement of Science; American College of Cardiology; FellowAmerican Medical Association; Ohio State Medical Association; North American

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Society of Pacing and Electrophysiology; Regular Member Pediatric ElectrophysiologySociety

Meyer, R: National Institute on Aging of the National Institutes of Health, Member ofthe Consortium for Inherited Connective Tissue Disorders

Michelfelder, E: Member, Fetal Therapeutics Team, Cincinnati Children’s HospitalMedical Center/Good Samaritan Hospital; Faculty presenter, “Valvular Insufficiency inthe Functional Single Ventricle,” 13th Annual Scientific Sessions of the American Societyof Echocardiography, Orlando, FL; Invited speaker, “Color Doppler M-ModeAssessment of Diastolic Function in Children”, Society of Pediatric EchocardiographySemi-Annual Meeting, Orlando, FL

Morrison, J: Reviewer, Metabolism, European Journal of Clinical Nutrition, Pediatrics,Journal of Pediatrics, Public Health Reports, and Annals of Epidemiology

Nelson, D: An Overview of Research in the Cardiac Intensive Care Setting – FourthInternational Symposium on Pediatric Cardiac Intensive Care, Miami, FL: Low CardiacOutput Syndrome after Congenital Heart Surgery; Medical Center Grand Rounds,University of Tuzla Medical Center, Tuzla, Bosnia: Low Cardiac Output Syndrome afterCongenital Heart Surgery; Croatian Medical Society, Zagreb, Croatia; Regulation ofBypass-related Inflammation; American College of Cardiology 51st Annual ScientificSession Atlanta, Ga.; 28th Annual Meeting, Congress of the European Society forPediatric and Neonatal Intensive Care, Mainz, Germany

Schwartz, S: American College of Cardiology 51st Annual Scientific Session, Atlanta,Ga. Ventricular Hypertrophy in Children: Is It Compensatory?

Shim, D: Member, American College of Cardiology; Member, Council onCardiovascular Disease in the Young of the American Heart Association; Member,Society for Cardiac Angiography and Interventions; Department of CardiologyRepresentative CHMC/SBI Quality Assurance Committee for Radiation ProducingDevices; Reviewer eHealth Clinical Content Advisory Group; Physician RepresentativeProfessional Business Service (PBS) steering committee; Advisory Editor PediatricCardiology. Editorial Board, Pediatric Cardiology, TheHeart.org

Spicer, R: Medical Society of UNOS and OPTN. Designated primary transplantphysician for the heart transplant program at Cincinnati Children’s Hospital

Uzark K: American Academy of Nursing (Fellow); American Nurses Association;National Association of Pediatric Nurse Associates and Practitioners; Council onCardiovascular Nursing, American Heart Association; Council on CardiovascularDisease in the Young, American Heart Association; Member, Pediatric CardiovascularNursing Committee, American Heart Association; Officer, Society of PediatricCardiology Nurses; Presenter, St. Luke, St Elizabeth, American Heart Association OhioValley Affiliate Covington, KY; Presenter, Cardiovascular Nursing Update-HeartDisease in Infants and Children National Conference of Neonatal Nursing, Anaheim, CA.

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Where Are They Now? Outcomes of Congenital Heart Disease. Also Cyanotic DefectsBypassing the Lungs

Wright, K: American College of Veterinary Internal Medicine (Cardiology); AmericanCollege of Veterinary Internal Medicine (Internal Medicine); North American Society forPacing and Electrophysiology; Pediatric Electrophysiologic Society; CouncilMembership, Cardiovascular Disease in the Young, American Heart Association;American College of Veterinary Internal Medicine, Specialty of Cardiology; CouncilMembership, Women in Cardiology, American Heart Association; American College ofVeterinary Internal Medicine, Specialty of Internal Medicine; American VeterinaryMedical Association; P.D. Cain Award, American Heart Association, Ohio ValleyAffiliate; Invited speaker at the 2001 American College of Veterinary Internal MedicineConference: “Monophasic Action Potentials: Principles, Methods, Uses”


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