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2/5/15Objective: How does DNA replication occur?
Do Now:http://www.youtube.com/watch?v=qy8dk5iS1f0
. Write the missing strand:ACTTGCTG
Template
DNA Replication• DNA replication: DNA makes a copy of itself
What does “to replicate” mean?If you start with one strand of DNA, how many strands will you end up with?
When• During what process does DNA replication
occur?
This occurs during cell division (mitosis)– Regeneration– Growth– Repair
DNA as a Template
Template Strand: Original strand of DNAComplementary Strand: New strand of DNA
ATTCGGTA
Template Strand
-T-A-A-G-C-C-A-T
Complimentary Strand
A closer look at DNA replication…
ATATCGCGCGCGCGCGCGCGTATA
A TA TC GC GC GC GC GC GC GC GT AT A
ATATCGCGCGCGCGCGCGCGTATA
ATATCGCGCGCGCGCGCGCGTATA
Recall…What are the 2
functions of enzymes?
DNA Helicase: An enzyme that “unwinds” or “unzips” the DNA strand
Recall…What are the 2
functions of enzymes?
DNA Polymerase: An enzyme that attaches the complimentary base pairs to the template strand
DNA Simulation
ATCTG
www.youtube.com/watch?v=rpwjZX_z5rg
http://www.youtube.com/watch?v=hfZ8o9D1tus
Turn and Talk
• With the person sitting next to you. In your notesheet under “How DNA replication occurs” write the steps of DNA replication, remembering what we did in the simulation to help you.
Summary
• Describe how DNA is replicated