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27748338 Breast Cancer Case Study

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    I N T R O D U C T I O N

    We acquire the strength of what we have overcome.

    Ralph Waldo Emerson

    So many women you know may have had breast cancer

    friends and neighbors, coworkers, relatives. It seems as if

    every time you turn around, breast cancer is being talked

    about in the newspaper or on TV. You may be fearful of

    developing breast cancer for the first time or of receiving a

    diagnosis after a mammogram or other testing. If youve had

    breast cancer, you may be fearful of a possible recurrence or

    even of the possibility that breast cancer could take your

    life.

    Breast cancer is an uncontrolled growth of breast cells.To better understand breast cancer, it helps to understand

    how any cancer can develop.

    Cancer develops when cells in a part of the body begin

    to grow out of control. Although there are many kinds of

    cancer, they all start because of out-of-control growth of

    abnormal cells. Normal body cells grow, divide, and die in an

    orderly fashion. During the early years of a person's life,

    normal cells divide more rapidly until the person becomes an

    adult. After that, cells in most parts of the body divideonly to replace worn-out or dying cells and to repair

    injuries.

    Because cancer cells continue to grow and divide, they

    are different from normal cells. Instead of dying, they

    outlive normal cells and continue to form new abnormal cells.

    Cancer cells develop because of damage to DNA. This substance

    is in every cell and directs all its activities. Most of the

    time when DNA becomes damaged the body is able to repair it.

    In cancer cells, the damaged DNA is not repaired. People can

    inherit damaged DNA, which accounts for inherited cancers.Many times though, a persons DNA becomes damaged by exposure

    to something in the environment, like smoking. Cancer cells

    can invade nearby healthy breast tissue and make their way

    into the underarm lymph nodes, small organs that filter out

    foreign substances in the body. If cancer cells get into the

    lymph nodes, they then have a pathway into other parts of the

    body. The breast cancers stage refers to how far the cancer

    cells have spread beyond the original tumor, A tumor can be

    benign (not dangerous to health) or malignant (has the

    potential to be dangerous).

    The term breast cancer refers to a malignant tumorthat has developed from cells in the breast. Usually breastcancer either begins in the cells of the lobules, which are

    the milk-producing glands, or the ducts, the passages that

    drain milk from the lobules to the nipple. Less commonly,

    breast cancer can begin in the stromal tissues, which include

    the fatty and fibrous connective tissues of the breast.

    Breast cancer is always caused by a genetic abnormality

    (a mistake in the genetic material). However, only 5-10% of

    cancers are due to an abnormality inherited from your mother

    or father. About 90% of breast cancers are due to genetic

    abnormalities that happen as a result of the aging processand the wear and tear of life in general.

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    Breast cancer is the second leading cause of cancer

    death in women, exceeded only by lung cancer. The chance that

    breast cancer will be responsible for a woman's death is

    about 1 in 35(about 3%). In 2008, about 40,480 women will die

    from breast cancer in the United States. Death rates from

    breast cancer have been declining since about 1990, with

    larger decreases in women younger than 50. These decreases

    are believed to be the result of earlier detection through

    screening and increased awareness, as well as improved

    treatment.

    The risk of developing most types of cancer can be

    reduced by changes in a person's lifestyle, for example, by

    quitting smoking and eating a better diet. The sooner a

    cancer is found and treatment begins, the better are the

    chances for living for many years.

    We have chosen the case because we want to broaden ourknowledge about Breast Cancer regarding to the nursing

    interventions and medical management. Cancer is the second

    leading cause of death and is a common case in the Surgical

    Ward of Baguio General Hospital and medical Center (BGHMC)

    that also prompted the group to research on the disease. The

    risk of developing most types of cancer can be reduced by

    changes in a person's lifestyle, for example, by quitting

    smoking and eating a better diet. The sooner a cancer is

    found and treatment begins, the better are the chances for

    living for many years.

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    P A T I E N T S P R O F I L E

    B i o g r a p h i c a l D a t a

    Patient X is 53 y/o, female, currently residing at

    Urdaneta City, Pangasinan was born on May 28, 1956 at Dagupan

    City, Benguet. She is married and was blessed with four

    children. She is currently living with her sister and her

    daughter here in Baguio due to her chemotherapy sessions at

    Baguio General Hospital and Medical Center.

    She is currently a housewife, managing the family and

    her only daughter. At present, source of income comes fromher husband working as a Computer Technician on a company.

    She was admitted last September 2008 at Baguio General

    Hospital and Medical Center (BGHMC) form MRM (modified

    Radical Mastectomy) with complaints of having pain in her

    right breast last December 2007.

    She attained a High school degree having the knowledge

    and ability to read and write. As for hobbies and interests,

    she certainly entertains herself by reading, cleaning and

    doing household chores and taking care of her family. Sheverbalized that the greatest gift from her is her only

    children.

    P r e s e n t I l l n e s s

    2 months Prior to Admission, patient complained, patient

    noted a mass before the incision area of the right breast.

    There was associated tenderness but no discharged.

    Consultation was sought and surgery was scheduled, hence

    admission.

    P a s t M e d i c a l H i s t o r y

    Patient X has no previous history of allergies. She had

    stated that she had previous records of hospitalization and

    operations. Last Operations were performed on September 2008.

    She underwent MRM (Modified Radical Mastectomy) and Status

    post a 6 cycle of Chemotherapy because of presence of tumor

    on her right breast. She has also a history of Hypertension.

    F a m i l y M e d i c a l H i s t o r y

    Patient X verbalized that she is the only one in the

    family that had cancer. She has stated that there were Family

    Medical Diseases known in their neither family nor hereditary

    sickness such as hypertension and most commonly in cancer.

    She declared that she had cancer due to an unhealthy

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    lifestyle established during her younger years. Her aunt had

    breast cancer and survived and her cousin died due to cancer.

    S o c i a l / E n v i r o n m e n t a l H i s t o r y

    Patient X is married and with four children. They are

    living in a bungalow type of house made of cement and wood

    just. Purchase of mineral water is their source of drinking

    water in the area. She also Garbage is collected on their

    area daily. She is fond of eating vegetables and fruits, less

    meat, and fish, and very selective on food. She dislikes and

    avoids eating salty foods; she is not very fond of eating

    sweets. She also stated that promotes drinking water,

    hydrating herself by drinking lots of water approximately 8-

    10 glasses a day, as she knows that it would be a benefit to

    her health. She also stated that she is a non-alcoholic and

    non-smoker.

    G y n e c o l o g i c a l H i s t o r y

    The patient was pregnant four times and delivered a

    four healthy children via Normal Spontaneous Delivery. During

    her pregnancy, she has a regular pre-natal check-up everymonth. She has a normal menstrual cycle (ranging from 3 to 4

    days every month). She has not undergone any abortion. She has

    no history of reproductive abnormalities.

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    P H Y S I C A L A S S E S S M E N T

    1 3 A R E A S O F A S S E S S M E N T

    A . P s y c h o s o c i a l S t a t u s

    Patient X is 53 y/o, female; currently residing at

    Urdaneta City, Pangasinan was born on March 18, 1956 at

    Baguio City, Benguet. She attained a High school degree

    having the knowledge and ability to read and write.

    As for now, she is currently a housewife, managing thefamily and her only daughter. At present, source of income

    comes from her husband working as a Computer Technician on a

    company. As for hobbies and interests, she certainly

    entertains herself by reading, cleaning and doing household

    chores and taking care of her family. She verbalized that the

    greatest gift from her is her only children.

    Under Erik Eriksons psychosocial development theory,

    the patient is under the stage of Generativity Versus

    Stagnation. She seems to have a good outlook in life.

    She was attentive in conversing with the health team

    members. She was cooperative to the nursing and medical

    interventions. She deals well with her watcher and visitors.

    They seem to have good relationship.

    B.M e n t a l S t a t u s a n d E m o t i o n a lS t a t u s

    The patient was conversant and was slightly oriented to

    date time, place, and people and to her present condition.

    During the duty, there were no observed mood swings and

    emotional changes. Her positive attitude was consistent all

    throughout. She answers questions and follow instructions

    appropriately.

    C . E n v i r o n m e n t a l S t a t u s

    The patient was admitted to Baguio General Hospital and

    Medical Center in Surgery East Ward of the Female Division on

    Bed 16. The ward has adequate lighting, good ventilation and

    warm temperature. It was maintained clean at all times by the

    cooperation of the Hospital Janitor, Staff Nurses and

    Watchers of each patient. The bed has no side rails. There

    are clean blankets and pillows for the patients use. There

    was a regular garbage collection in the hospital where in

    there is proper regulation. The garbage bins are placed on

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    the hallway of the ward which is managed by the Hospital

    Janitor.

    D . S e n s o ry S t a t u s

    1. Visual Status

    The patients pupils are equally rounded. There are no

    reduced accommodation to light changes when the penlight was

    directed to the eyes. Based on her age, she has diminished

    visual acuity nor reduction in visual field. She does not

    have difficulties in seeing far away objects and recognizing

    people, and does wear corrective devices such as eye glasses

    if needed. She has the capability to read due to good visual

    acuity.

    2. Auditory Status

    She has no difficulties in hearing soft voices upon

    seeing her conversing with her watcher in a whispering

    manner. She was able to determine from what direction the

    sound of the voices were coming from as observed when she

    turned her head towards the direction of the person she was

    talking to. There was no impacted cerumen upon inspection.

    The ears are symmetrical and in lined with the outer cantus

    of the eyes.

    3. Olfactory Status

    Air is felt in the nose when she exhaled. Nasal mucosais intact, smooth and moist pink upon inspection. She was

    able to discriminate foul odor as noted when she complained

    about the bad smell of the comfort room.

    4. Gustatory Status

    She is able to determine between different tastes such

    as sour, sweet, bitter, and salty. She could also taste anyflavor or dish served to her.

    5. Tactile Status

    She was able to perceive hotness. She was also able to

    perceive cold as noted when she asked the student nurse why

    the thermometer is cold. Pain was noted when she grimaced

    upon the administration of intravenous medications.

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    6. Language Perception and Formation

    The patient is fluent in Ilocano, Tagalog and in

    English. She can understand Ilocano, Tagalog and English

    language but fairly understandsother dialects. She verbalizes

    her needs.

    A . M o t o r S t a t u s

    Patient can move all her extremities very well. She has

    no limited movement from her bed and can barely stand on her

    own. She could ambulate around the ward and walks to the

    comfort room to refresh herself without no assistance.

    B . N u t r i t i o n a l S t a t u s

    During her hospitalization, The doctor advised her to

    take in foods that would boost her immune system, eating a

    balanced meal composing largely on fruits and vegetables and

    small amount of meat. She has a good appetite. Upon

    palpation, there is no abdominal tenderness.

    C . E l i m i n a t i o n S t a t u s

    During hospitalization, her urination ranges from 3-4

    times per day only. This must have been because she takes

    water at all.

    On the days that we handled her, she had not defecated

    during our 3-11 shift. She described her stool as brownish

    and depending on the foods colors that she intake in.

    D . F l u i d a n d E l e c t r o l y t e s t a t u s

    Before the hospitalization, Mrs. X drinks large amounts

    of water just about 8-10 glasses of water a day. She drinks

    water every after meal, as she knows that it would be a

    benefit to her health.

    During her hospitalization, she did drink much water.

    There was insertion of IV administration of D5LRS 1000 Liters

    regulated at 21 drops per minute (gtts/min).

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    E . C i r c u l a t o r y S t a t u s

    Her pulse rate ranges from 62-95 beats per minute which

    is within the normal limits. However, her blood pressure

    ranges from 100/60- 130/70 which also her normal BP. She hasa history of hypertension. Her capillary refill is about 2-3

    seconds which is normal.

    F . R e s p i r a t o r y S t a t u s

    Her respiration ranges from 16-22 breaths per minutes.

    She has no episodes of difficulty in breathing.

    G . T e m p e r a t u r e S t a t u s

    During her first day of hospitalization, she has no

    fever. Her temperature ranges from 36.9 37.2 degrees

    centigrade which is within normal range.

    H . I n t e g u m e n t a r y S t a t u s

    Skin was moist. Lips and buccal mucosa were not dry.

    There is normal Skin turgor which goes back normally. There

    were noted incision on the left breast due to her mastectomy

    operation last 2008 at Cagayan de Oro.

    I . C o m f o r t a n d R e s t S t a t u s

    During our shift, she was comfortable in sleeping butthere are episodes where she cannot sleep due to ward

    setting. The lights are on and the Noise surrounding the ward

    could irritate her disturbance of sleeping.

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    Band 0 . 0 0 - 0 . 0 5 1 . 0 0

    T O T A L 1 . 0 0

    Red Cell Count F 4 . 0 4 - 5 . 4 8 x

    1 0 1 2 / L

    Platelet Count 1 5 0 - 4 0 0 x 1 0 g / l M a r k e d l y

    i n c r e a s e d

    LE Cell Prep.

    Malarial Smear

    Bleeding Time 1 - 5 m i n u t e s

    Clotting Time 2 - 6 m i n u t e s

    Lee & white C.T 5 - 1 0 m i n u t e s

    P R O T H R O M B I N T I M E ( P T )

    Patient 1 0 - 1 4 s e c o n d s

    Control 1 0 . 8 - 1 3 . 8s e c o n d s

    INR

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    % Activity

    P A R T I A L P R O T H R O M B I N T I M E ( P T T )

    Patient 2 6 - 3 6 s e c o n d s

    Control 2 9 . 6 - 3 7 . 6

    s e c o n d s

    E R Y T H R O C Y T E S E D I M E N T A T I O N R A T E

    Wintrobe Method F 0 - 2 0 m m / H r

    Westergren Method A d u l t 0 - 1 0 m m / H r

    Retailocyte Count 0 . 5 - 1 . 5 %

    R E M A R K S :

    Midcells may include less frequently occurring and rare correlating to monotype, eosinophils, basophils,

    blast and other precursor.

    Blood Type: O

    Rh: Positive

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    I M P L I C A T I O N :

    Chemotherapy affects production of white blood cells in the bone marrow. Normally white blood cells

    help fight off infection. After chemotherapy, if your white blood cells are low, you are more likely to get

    infections. Any infection can also worsen more quickly a trivial infection could become life threatening

    within hours if it isnt treated.

    When your white blood cell count is at its lowest you can feel very tired (fatigued). Some people also

    say they feel depressed. This can be really hard to deal with and make you wonder if you really want to go

    on with your treatment. Try to hang in there. Things should improve and you will start to feel better again

    before your next treatment, as your blood counts rise. Unfortunately, they'll go down again after each

    treatment. But once your treatment is finished your blood cell counts will remain at normal levels.

    13

    http://www.cancerhelp.org.uk/help/default.asp?page=10267http://www.cancerhelp.org.uk/help/default.asp?page=13395http://www.cancerhelp.org.uk/help/default.asp?page=10267http://www.cancerhelp.org.uk/help/default.asp?page=13395
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    A N A T O M Y A N D P H Y S I O L O G Y

    T h e B r e a s t s

    In order to understand breast cancer, it helps to have

    some basic knowledge about the normal structure of the

    breasts. The female breast is made up mainly of lobules

    (milk-producing glands), ducts (tiny tubes that carry the

    milk from the lobules to the nipple), and stroma (fatty

    tissue and connective tissue surrounding the ducts and

    lobules, blood vessels, and lymphatic vessels).

    Most breast cancers begin in the cells that line the

    ducts (ductal cancers). Some begin in the cells that line the

    lobules (lobular cancers), while a small number start in

    other tissues.

    T h e L y m p h a t i c s y s t e m

    The lymph system is important to understand because it

    is one of the ways in which breast cancers can spread. This

    system has several parts. Lymph nodes are small, bean-shaped

    collections of immune system cells (cells that are important

    in fighting infections) that are connected by lymphatic

    vessels. Lymphatic vessels are like small veins, except that

    they carry a clear fluid called lymph (instead of blood) away

    from the breast. Lymph contains tissue fluid and waste

    products, as well as immune system cells.

    Breast cancer cells can enter lymphatic vessels and

    begin to grow in lymph nodes. Most lymphatic vessels in the

    breast connect to lymph nodes under the arm (axillary nodes).

    Some lymphatic vessels connect to lymph nodes inside the

    chest (internal mammary nodes) and those either above or

    below the collarbone (supraclavicular or infraclavicular

    nodes).

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    Knowing if the cancer cells have spread to lymph nodes

    is important because if it has, there is a higher chance that

    the cells could have also gotten into the bloodstream and

    spread (metastasized) to other sites in the body.

    The more lymph nodes that have breast cancer, the more

    likely it is that the cancer may be found in other organs as

    well. This is important to know because it could affect your

    treatment plan. Still, not all women with cancer cells in

    their lymph nodes develop metastases, and in some cases a

    woman can have negative lymph nodes and later develop

    metastases.

    F i b r o c y s t i c c h a n g e s

    Most lumps turn out to be fibrocystic changes. The term

    "fibrocystic" refers to fibrosis and cysts. Fibrosis is the

    formation of fibrous (scar-like) tissue, and cysts are fluid-

    filled sacs.

    Fibrocystic changes can cause breast swelling and pain.

    This often happens just before a woman's menstrual period is

    about to begin. Her breasts may feel lumpy and, sometimes, she

    may notice a clear or slightly cloudy nipple discharge.

    B e n i g n B r e a s t L u m p s

    Benign breast tumors such as fibroadenomas or

    intraductal papillomas are abnormal growths, but they are not

    cancerous and do not spread outside of the breast to other

    organs.They are not life threatening. Still, some benign

    breast conditions are important because women with these

    conditions have a higher risk of developing breast cancer.

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    P A T H O P H Y S I O L O G Y O F T H E D I S E A S E

    17

    Predisposing

    Factors:

    Age

    Gender

    ETIOLOGY:

    Unknown

    Precipitating Factors:

    exposure toradiation andcertain chemicals

    having a siblingwith leukemia

    HTLV-1 virus genetic

    abnormalities

    Somatic mutations in

    the DNA

    Activate oncogene/

    deactivate tumor-

    supppresor gene

    Malignant transformation

    of lymphoid stem cells

    Uncontrolled proliferation

    of lymphoblast in the bone

    marrow

    s/sx:

    bone pain

    Treatment:

    Analgesic

    Lymphoblast replace the

    normal marrow elements

    Diagnostic

    Test:

    BM aspiration

    Treatment:

    RemissionInductionTherapy

    ConsolidationandMaintenanceTherapy

    BM

    Decreased productionof normal blood cells

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    P A T H O P H Y S I O L O G Y O F T H E

    D I S E A S E

    Breast cancer may be classified pathologically asnoninvasive (in situ) or invasive (infiltrating). The

    noninvasive carcinomas are generally thought to be

    antecedents of invasive carcinoma.

    Intraductal carcinoma (ductal carcinoma in situ) is the

    most common noninvasive carcinoma among elderly women. It is

    generally multicentric, and

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    Acquired gene mutations

    Most DNA mutations related to breast cancer, however,

    occur in single breast cells during a woman's life rather

    than having been inherited. These acquired mutations ofoncogenes and/or tumor suppressor genes may result from other

    factors, such as radiation or cancer(22 of 121) causing

    chemicals. But so far, the causes of most acquired mutations

    that could lead to breast cancer remain unknown. Most breast

    cancers have several gene mutations that are acquired.

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    N U R S I N G C A R E A N D

    M A N A G E M E N T

    L I S T O F I D E N T I F I E D P R O B L E M S

    A C T U A L P R O B L E M S

    1. hair loss leading to disturbed body image

    2. easy bruising or bleeding (due to low blood platelet

    counts)

    3. fatigue (due to low red blood cell counts and other

    reasons)

    4. loss of appetite

    P O T E N T I A L P R O B L E M S

    1. nausea and vomiting

    2. increased chance of infections (due to low white blood

    cell counts)

    3. mouth sores

    P R I O R I T I Z E D P R O B L E M S

    1. Fatigue (due to low red blood cell counts and otherreasons)

    Fatigue is a common health complaint. It is, however,

    one of the hardest terms to define, and a symptom of

    many different conditions.

    Fatigue, also known as weariness, tiredness, exhaustion,

    or lethargy, is generally defined as a feeling of lack

    of energy. Fatigue is not the same as drowsiness, but

    the desire to sleep may accompany fatigue. Apathy is a

    feeling of indifference that may accompany fatigue or

    exist independently.

    2. Hair Loss Leading Disturbed Body Image

    Some medicines can cause hair loss. This type of hair

    loss improves when you stop taking the medicine.Medicines that can cause hair loss include blood

    thinners (also called anticoagulants), medicines used

    for gout, medicines used in chemotherapy to treat

    cancer, vitamin A (if too much is taken), birth control

    pills and antidepressants.

    Body image is the attitude a person has about the actual

    or perceived structure or function of all or part of his

    or her body. This attitude is dynamic and is altered

    through interaction with other persons and situations

    21

    http://www.emedicinehealth.com/script/main/art.asp?articlekey=5610http://www.emedicinehealth.com/script/main/art.asp?articlekey=26114http://www.emedicinehealth.com/script/main/art.asp?articlekey=4138http://www.emedicinehealth.com/script/main/art.asp?articlekey=59135http://www.emedicinehealth.com/script/main/art.asp?articlekey=5610http://www.emedicinehealth.com/script/main/art.asp?articlekey=26114http://www.emedicinehealth.com/script/main/art.asp?articlekey=4138http://www.emedicinehealth.com/script/main/art.asp?articlekey=59135
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    and influenced by age and developmental level. As an

    important part of ones self-concept, body image

    disturbance can have profound impact on how individuals

    view their overall selves.

    3. loss of appetite

    A decreased appetite is when you have a reduced desire

    to eat. This occurs despite the body's basic caloric

    (energy) needs.

    Any illness can affect a previously hearty appetite. If

    the illness is treatable, the appetite should return

    when the condition is cured.

    Loss of appetite can cause unintentional weight loss.

    Depression in the elderly is a common cause of weightloss that is not explained by other factors.

    22

    http://www.nlm.nih.gov/medlineplus/ency/article/003107.htmhttp://www.nlm.nih.gov/medlineplus/ency/article/003107.htm
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    N U R S I N G C A R E P L A N S

    ACTUAL

    ASSESSMENT EXPLANATION OF

    THE PROBLEM

    PLANNING IMPLEMENATION RATIONALE EVALUATION

    S> Medyonanghihina pa ako

    O> Appears weak

    Slow

    Movements

    noted

    Good Skin

    Turgor

    Coherent and

    Conversant

    Needs

    assistance in

    performing

    ADLs

    A> Activity

    Intolerance

    Related to

    Weakness

    The length ofChemotherapy

    treatment depends

    on whether the

    cancer shrinks,

    how much it

    shrinks, and how a

    woman tolerates

    length of

    treatment. Some of

    the most common

    possible side

    effect is fatigue

    (due to low red

    blood cell counts

    and other reasons)

    STO> After 8 hoursof Nursing

    Intervention the

    patient will be

    able to identify

    techniques to

    enhance activity

    tolerance such as:

    - gradual increase

    in activity level

    as tolerated

    - rest in between

    activities

    LTO> After 8 days

    of Nursing

    Intervention, the

    DX> Monitor VitalSigns and Record

    Assess

    Ability to

    ambulate

    Assess

    capillary

    Refill

    Assess skin

    turgor.

    TX> Promote

    Adequate Rest

    Assist withactivities

    Anticipate

    For baselinedata.

    To determine

    activity

    intolerance

    To determine

    circulatory

    problems.

    To determine

    hydration.

    To enhance

    ability to

    participate

    with

    activities

    To protect

    client frominjury

    To promote

    STO> Goal is metif the patient

    will be able to

    identify

    techniques to

    enhance activity

    tolerance such as:

    - gradual increase

    in activity level

    as tolerated

    - rest in between

    activities

    LTO> Goal is met

    if the patient

    will be able to

    report an increase

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    patient will be

    able to report an

    increase in

    activity

    intolerance.

    Needs

    EDX> Encourage

    expression of

    feelings

    Suggest Use

    of Relaxation

    Techniques

    such as

    visualization

    and guided

    imagery.

    wellness

    To determine

    contributing

    factors

    To Enhance

    Ability to

    participate

    in activities

    in activity

    intolerance.

    25

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    27

    ASSESSMENT EXPLANATION

    OF THE

    PROBLEM

    PLANNING IMPLEMENATION RATIONALE EVALUATION

    S> Nakakahiya

    makakalbo ako

    O>

    Coherent andConversant

    Submits self

    to Nursing

    Procedure and

    Care done

    A> Disturbed

    Body Image

    realted to

    illness

    treatment.

    The length of

    Chemotherapy

    treatment depends

    on whether the

    cancer shrinks,how much it

    shrinks, and how a

    woman tolerates

    length of

    treatment. Some of

    the most common

    possible side

    effect is hair

    loss.

    STO> After 8

    hours of Nursing

    Intervention the

    patient will be

    able to verbalizeunderstanding of

    body changes

    LTO> After 1 day

    of Nursing

    Intervention, the

    patient will be

    able to verbalize

    acceptance of

    self in situation

    in the effects of

    therapeutic

    regimen.

    DX> Monitor vital

    signs and record

    Determine

    patients

    perception of

    cancer and

    cancer

    treatments.

    TX> Ask for

    patient for verbal

    feedback, and

    correct

    misconception

    about individuals

    type of cancer and

    treatment.

    Provide

    anticipatory

    guidance with

    patient

    regarding

    treatment

    Protocol,

    length of

    For baseline

    data

    Aids in

    identification

    of ideas,attitudes and

    fears,

    misconception

    Misconceptions

    about cancer may

    be more

    disturbing than

    facts and can

    interfere with

    treatments/

    delay healing.

    Accurate and

    concise

    information

    helps dispel

    fears andanxiety, helps

    clarify the

    expected

    routine.

    STO> Goal is met

    if patient will

    be able to

    verbalize

    understanding ofbody changes.

    LTO> Goal is met

    if patient will

    be able to

    verbalize

    acceptance of

    self in situation

    in the effects of

    therapeutic

    regimen.

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    30

    ASSESSMENT EXPLANATION

    OF THE

    PROBLEM

    PLANNING IMPLEMENATION RATIONALE EVALUATION

    S>

    O> Coherent and

    Conversant

    Submits selfto Nursing

    Procedure and

    Care done

    A>Risk for

    Infection

    related to

    inadequate

    secondary

    defenses and

    immunosuppress

    ion secondary

    to dose-

    limiting side

    effect of

    chemotherapy.

    This can often

    have a major

    effect on the

    immune system and

    may reduce thebody's defenses

    against infection

    for some months,

    both during and

    after treatment.

    This is because

    chemotherapy

    reduces the

    production of

    white blood cells

    by the bone

    marrow. People

    having

    chemotherapy are

    particularly at

    risk of picking upinfections between

    714 days after

    the chemotherapy,

    when the level of

    STO> After 8

    hours of Nursing

    Intervention the

    patient will be

    able to verbalizeunderstanding of

    Having cancer or

    treatment for cancer

    can weaken your

    immune system. This

    makes it more likely

    that you will pick

    up an infection and

    develop a fever.

    LTO> After 1 day

    of Nursing

    Intervention, the

    patient will be

    able to

    demonstrate proper

    aseptic techniques

    preventing further

    infection such as

    DX> Monitor Vital

    Signs and record.

    Monitor

    Temperature

    TX> Assess all

    systems for signs

    and symptoms of

    infection on a

    continual basis.

    Promote

    For baseline

    Data.

    Temperature

    elevation may

    occur becauseof various

    factors such

    as

    chemotherapy

    side effects.

    Early

    recognition

    and

    intervention

    may prevent

    progression

    to more

    serious

    situation.

    Limits

    fatigue, yetencourages

    sufficient

    movement to

    prevent

    STO> Goal is met

    if patient will

    be able to

    verbalize

    understanding ofHaving cancer or

    treatment for cancer

    can weaken your

    immune system. This

    makes it more likely

    that you will pick

    up an infection and

    develop a fever.

    LTO> Goal is met

    if patient will be

    able to

    demonstrate proper

    aseptic techniques

    preventing further

    infection such as

    proper hand

    washing.

    http://www.cancerbackup.org.uk/Treatments/Chemotherapyhttp://www.cancerhelp.org.uk/help/default.asp?page=118http://www.cancerhelp.org.uk/help/default.asp?page=118http://www.cancerbackup.org.uk/Treatments/Chemotherapyhttp://www.cancerhelp.org.uk/help/default.asp?page=118http://www.cancerhelp.org.uk/help/default.asp?page=118
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    D R U G S T U D Y

    32

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    33

    Generic name/brand name/

    classification

    Action and Indication Route/Dosage/Date prescribe Nursing consideration

    tamoxifen citrate(ta mox' i fen)

    Apo-Tamox (CAN),

    Nolvadex, Novo-Tamoxifen

    (CAN), Tamofen (CAN),

    Tamone (CAN)

    Pregnancy Category D

    Drug class

    Antiestrogen

    Therapeutic actions

    Potent antiestrogenic effects:

    competes with estrogen for binding

    sites in target tissues, such as

    the breast.

    Indications

    Adjunct with cytotoxic

    chemotherapy following radical

    or modified radical mastectomy

    to delay recurrence of

    surgically curable breast

    cancer in postmenopausal women

    or women >50 y with positive

    axillary nodes

    Treatment of advanced,

    metastatic breast cancer in

    women and men; alternative to

    oophorectomy or ovarian

    radiation in premenopausal

    women Preventative therapy for women

    at high risk for breast cancer

    Unlabeled uses: treatment of

    Dosage

    Available Forms: Tablets--10,

    20 mg

    Adult

    Breast cancer:

    20---40 mg/d PO for 5 y.

    Reduction in breast cancer

    incidence:

    20 mg/d PO for 5 y.

    Pharmacokinetics

    Metabolism: Hepatic, T1/2:

    7---14 d

    Distribution: Crosses

    placenta; enters breast

    milk

    Excretion: Feces

    Take the drug

    twice a day, in

    the morning and

    evening.

    The following

    side effects may

    occur: bone pain;

    hot flashes

    (staying in cool

    temperatures may

    help); nausea,

    vomiting (small,

    frequent meals

    may help); weight

    gain; menstrual

    irregularities;

    dizziness,

    headache, light-

    headedness (use

    caution if

    driving or

    performing tasks

    that require

    alertness).

    This drug can

    cause serious

    fetal harm and

    must not be taken

    during pregnancy.

    Ro

    ut

    e

    On

    se

    t

    Pe

    akOr

    al

    Va

    ri

    es

    4-

    --

    7

    h

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    35

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    S U M M A R Y O F F I N D I N G S

    Vital Signs were assessed and properly documented. The

    patient was on IVF of D5NSS 1L, it was regulated and

    monitored. IVF flow rate and patency on site were checked.

    The significant others was encouraged to converse with the

    patient and instructed to maintain bed rest. The significant

    others was endorsed to increase fluid intake. The diet as

    tolerated was encouraged promoting vegetables and fruits in

    giving vitamins and minerals that could support the bodys

    defenses. Medications were prepared to the patient Treatment

    for these symptoms are a standard fluid rehydration therapy

    in order to maintain blood pressure. If circulatory failure

    is not reversed, death may follow. Rapport was established

    and integrated with the significant others. Safety was

    ensured with the close monitoring on the patient.

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    C O N C L U S I O N

    If a newly diagnosed Breast cancer patient asked you to

    define cancer, could you tell her that she has still hope? We

    all have heard the word "cancer" many times, however very few

    people understand the disease and how it develops.

    Cancer is a complex group of over 100 different types of

    cancer. Cancer can affect just about every organ in the human

    body.

    All cancers are different, and require different

    treatment. What may be effective for prostate cancer,

    probably will not be for bladder cancer. Diagnosing cancer

    will vary as well, depending on the organ affected.

    End-of-Life Issues

    Palliative care, which provides physical, emotional, and

    spiritual relief, must be provided with attempts for curative

    therapy and becomes the exclusive goal when cure cannot be

    expected at all stages of breast cancer, treatment needs to

    be modified for life expectancy. For patients with metastatic

    disease for which cure is not attainable, the physician

    should clarify the goals of care through frequent, clear

    discussions with the patient and, when appropriate, the

    family.

    All should recognize that cognitive impairment alone

    does not exclude the patient from participating in decision

    making, because some patients with impaired cognition are

    able to understand, explain the consequences of, and voice an

    opinion about certain treatment options. Pain from bony

    metastases should be treated as described above with

    nonsteroidal anti-inflammatory drugs, pamidronate, local

    radiation, and strontium 89 rather than with opioids if

    possible. Palliative chemotherapy may be useful when the

    tumor invades vital organs.

    37

    http://cancer.about.com/od/cancerlistaz/a/typesofcancers.htmhttp://cancer.about.com/od/cancerlistaz/a/typesofcancers.htmhttp://cancer.about.com/od/treatmentoptions/a/options.htmhttp://cancer.about.com/od/prostatecancer/http://cancer.about.com/od/bladdercancer/http://cancer.about.com/od/cancerlistaz/a/typesofcancers.htmhttp://cancer.about.com/od/cancerlistaz/a/typesofcancers.htmhttp://cancer.about.com/od/treatmentoptions/a/options.htmhttp://cancer.about.com/od/prostatecancer/http://cancer.about.com/od/bladdercancer/
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    R E C O M M E N D A T I O N

    Health care providers should:

    a. Should continuously monitor the vital signs of the

    patient.

    b. Observe the patient to avoid development of

    complications.

    c. Promote safety of the patient.

    d. Educate patient and significant others about the

    disease, and

    e. Explain the procedure done to the patient. The

    evaluation and diagnosis of Breast Cancer is based on

    the presenting symptoms and history combined with a

    focused physical assessment, imaging studies, and

    possibly a functional study of the breast.

    Significant others should:

    a. Actively cooperate in the rendering of care for the

    patient.

    b. Be sensitive to the needs.

    c. In addition, every effort is made to retrieve andanalyze breast has passed spontaneously or retrieved

    through aggressive interventions.

    d. Cooperate with the health care providers in the

    implementation of her Health Care programs.

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    A P P E N D I C E S

    S t a g e s o f B r e a s t C a n c e r

    Stage Definition

    Stage0

    Cancer cells remain inside the breast duct, withoutinvasion into normal adjacent breast tissue.

    StageI

    Cancer is 2 centimeters or less and is confined to thebreast (lymph nodes are clear).

    Stage

    IIA

    No tumor can be found in the breast, but cancer cellsare found in the axillary lymph nodes (the lymph nodesunder the arm)ORthe tumor measures 2 centimeters or smaller and has

    spread to the axillary lymph nodesORthe tumor is larger than 2 but no larger than 5centimeters and has not spread to the axillary lymphnodes.

    StageIIB

    The tumor is larger than 2 but no larger than 5centimeters and has spread to the axillary lymph nodesORthe tumor is larger than 5 centimeters but has notspread to the axillary lymph nodes.

    StageIIIA

    No tumor is found in the breast. Cancer is found in

    axillary lymph nodes that are sticking together or toother structures, or cancer may be found in lymph nodesnear the breastboneORthe tumor is any size. Cancer has spread to theaxillary lymph nodes, which are sticking together or toother structures, or cancer may be found in lymph nodesnear the breastbone.

    StageIIIB

    The tumor may be any size and has spread to the chestwall and/or skin of the breastAND

    may have spread to axillary lymph nodes that areclumped together or sticking to other structures, orcancer may have spread to lymph nodes near thebreastbone.

    Inflammatory breast cancer is considered at least stageIIIB.

    Stage

    IIIC

    There may either be no sign of cancer in the breast ora tumor may be any size and may have spread to thechest wall and/or the skin of the breastAND

    the cancer has spread to lymph nodes either above orbelow the collarboneANDthe cancer may have spread to axillary lymph nodes orto lymph nodes near the breastbone.

    StageIV

    The cancer has spread or metastasized to otherparts of the body.

    39

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    B r e a s t C a n c e r R i s k F a c t o r s

    A risk factor is anything that increases your risk of

    developing breast cancer. Many of the most important risk

    factors for breast cancer are beyond your control, such as

    age, family history, and medical history. However, there are

    some risk factors you can control, such as weight, physicalactivity, and alcohol consumption.

    Be sure to talk with your doctor about all of your

    possible risk factors for breast cancer. There may be steps

    you can take to lower your risk of breast cancer, and your

    doctor can help you come up with a plan. Your doctor also

    needs to be aware of any other risk factors beyond your

    control, so that he or she has an accurate understanding of

    your level of breast cancer risk. This can influence

    recommendations about breast cancer screening what tests to

    have and when to start having them.

    I . R i s k f a c t o r s y o u c a n c o n t r o l

    Weight. Being overweight is associated with increased risk ofbreast cancer, especially for women after menopause. Fat

    tissue is the bodys main source of estrogen after menopause,

    when the ovaries stop producing the hormone. Having more fat

    tissue means having higher estrogen levels, which can

    increase breast cancer risk.

    Diet. Diet is a suspected risk factor for many types ofcancer, including breast cancer, but studies have yet to show

    for sure which types of foods increase risk. Its a good idea

    to restrict sources of red meat and other animal fats

    (including dairy fat in cheese, milk, and ice cream), because

    they may contain hormones, other growth factors, antibiotics,

    and pesticides. Some researchers believe that eating too much

    cholesterol and other fats are risk factors for cancer, and

    studies show that eating a lot of red and/or processed meats

    is associated with a higher risk of breast cancer. A low-fat

    diet rich in fruits and vegetables is generally recommended.

    For more information, visit our page on healthy eating to

    reduce cancer risk in the Nutrition section.

    Exercise. Evidence is growing that exercise can reduce breastcancer risk. The American Cancer Society recommends engaging

    in 45-60 minutes of physical exercise 5 or more days a week.

    Alcohol consumption. Studies have shown that breast cancerrisk increases with the amount of alcohol a woman drinks.

    Alcohol can limit your livers ability to control blood

    levels of the hormone estrogen, which in turn can increase

    risk.

    Smoking. Smoking is associated with a small increase inbreast cancer risk.

    Exposure to estrogen. Because the female hormone estrogenstimulates breast cell growth, exposure to estrogen over long

    periods of time, without any breaks, can increase the risk of

    breast cancer. Some of these risk factors are under your

    control, such as:

    taking combined hormone replacement therapy (estrogen

    and progesterone; HRT) for several years or more, or

    taking estrogen alone for more than 10 years

    being overweight

    regularly drinking alcohol

    Recent oral contraceptive use. Using oral contraceptives(birth control pills) appears to slightly increase a womans

    40

    http://www.breastcancer.org/tips/nutrition/nutrition_bc/reduce_risk.jsphttp://www.breastcancer.org/tips/nutrition/nutrition_bc/reduce_risk.jsphttp://www.breastcancer.org/tips/nutrition/nutrition_bc/reduce_risk.jsphttp://www.breastcancer.org/tips/nutrition/nutrition_bc/reduce_risk.jsp
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    risk for breast cancer, but only for a limited period of

    time. Women who stopped using oral contraceptives more than

    10 years ago do not appear to have any increased breast

    cancer risk.

    Stress and anxiety. There is no clear proof that stress and

    anxiety can increase breast cancer risk. However, anythingyou can do to reduce your stress and to enhance your comfort,

    joy, and satisfaction can have a major effect on your quality

    of life. So-called mindful measures (such as meditation,

    yoga, visualization exercises, and prayer) may be valuable

    additions to your daily or weekly routine. Some research

    suggests that these practices can strengthen the immune

    system.

    I . R i s k f a c t o r s y o u c a n tc o n t r o l

    Gender. Being a woman is the most significant risk factor fordeveloping breast cancer. Although men can get breast cancer,too, womens breast cells are constantly changing and

    growing, mainly due to the activity of the female hormones

    estrogen and progesterone. This activity puts them at much

    greater risk for breast cancer.

    Age. Simply growing older is the second biggest risk factorfor breast cancer. From age 30 to 39, the risk is 1 in 233,

    or .43%. That jumps to 1 in 27, or almost 4%, by the time you

    are in your 60s.

    Family history of breast cancer. If you have a first-degree

    relative (mother, daughter, sister) who has had breastcancer, or you have multiple relatives affected by breast or

    ovarian cancer (especially before they turned age 50), you

    could be at higher risk of getting breast cancer.

    Personal history of breast cancer. If you have already beendiagnosed with breast cancer, your risk of developing it

    again, either in the same breast or the other breast, is

    higher than if you never had the disease.

    Race. White women are slightly more likely to develop breastcancer than are African American women. Asian, Hispanic, and

    Native American women have a lower risk of developing anddying from breast cancer.

    Radiation therapy to the chest. Having radiation therapy tothe chest area as a child or young adult as treatment for

    another cancer significantly increases breast cancer risk.

    The increase in risk seems to be highest if the radiation was

    given while the breasts were still developing (during the

    teen years).

    Breast cellular changes. Unusual changes in breast cellsfound during a breast biopsy (removal of suspicious tissue

    for examination under a microscope) can be a risk factor for

    developing breast cancer. These changes include overgrowth ofcells (called hyperplasia) or abnormal (atypical) appearance.

    Exposure to estrogen. Because the female hormone estrogenstimulates breast cell growth, exposure to estrogen over long

    periods of time, without any breaks, can increase the risk of

    breast cancer. Some of these risk factors are not under your

    control, such as:

    starting menstruation (monthly periods) at a young age

    (before age 12)

    going through menopause (end of monthly cycles) at a

    late age (after 55)

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    exposure to estrogens in the environment (such as

    hormones in meat or pesticides such as DDT, which

    produce estrogen-like substances when broken down by the

    body)

    Pregnancy and breastfeeding. Pregnancy and breastfeeding

    reduce the overall number of menstrual cycles in a womanslifetime, and this appears to reduce future breast cancer

    risk. Women who have never had a full-term pregnancy, or had

    their first full-term pregnancy after age 30, have an

    increased risk of breast cancer. For women who do have

    children, breastfeeding may slightly lower their breast

    cancer risk, especially if they continue breastfeeding for 1

    1/2 to 2 years. For many women, however, breastfeeding for

    this long is neither possible nor practical.

    DES exposure. Women who took a medication calleddiethylstilbestrol (DES), used to prevent miscarriage from

    the 1940s through the 1960s, have a slightly increased riskof breast cancer. Women whose mothers took DES during

    pregnancy may have a higher risk of breast cancer as well.

    For more detailed information about risk factors for breast

    cancer, visit our Lower Your Risk section.

    S y m p t o m s & D i a g n o s i s

    Breast cancer symptoms vary widely from lumps to

    swelling to skin changes and many breast cancers have no

    obvious symptoms at all. Symptoms that are similar to thoseof breast cancer may be the result of non-cancerous

    conditions like infection or a cyst.

    Breast self-exam should be part of your monthly health care

    routine, and you should visit your doctor if you experience

    breast changes.

    Mammogram.

    If you're over 40 or at a high risk for the

    disease, you should also have an annual mammogram.

    Physical Exam by a doctor. The earlier breast cancer is found

    and diagnosed, the better your chances of beating it.

    The actual process of diagnosis can take weeks and involve

    many different kinds of tests. Waiting for results can feel

    like a lifetime. The uncertainty stinks. But once you

    understand your own unique big picture, you can make better

    decisions. You and your doctors can formulate a treatment

    plan tailored just for you.

    R i s k o f D e v e l o p i n g B r e a s t

    C a n c e r

    The term risk is used to refer to a number or

    percentage that describes how likely a certain event is to

    occur. When we talk about factors that can increase or

    decrease the risk of developing breast cancer, either for the

    first time or as a recurrence, we often talk about two

    different types of risk: absolute risk and relative risk.

    42

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    I . A b s o l u t e r i s k

    Absolute risk is used to describe an individualslikelihood of developing breast cancer. It is based on thenumber of people who will develop breast cancer within a

    certain time period. Absolute risk also can be stated as a

    percentage.

    The absolute risk of developing breast cancer during a

    particular decade of life is lower than 1 in 8. The younger

    you are, the lower the risk. For example:

    From age 30 to 39, absolute risk is 1 in 233, or 0.43%. This

    means that 1 in 233 women in this age group can expect to

    develop breast cancer. Put another way, your odds of

    developing breast cancer if you are in this age range are 1 in

    233.

    From age 40 to 49, absolute risk is 1 in 69, or 1.4%.

    From age 50 to 59, absolute risk is 1 in 38, or 2.6%.

    From age 60 to 69, absolute risk is 1 in 27, or 3.7%.

    I . R e l a t i v e r i s k

    Relative risk is a number or percentage that comparesone groups risk of developing breast cancer to anothers.This is the type of risk frequently reported by research

    studies, which often compare groups of women with different

    characteristics or behaviors to determine whether one group

    has a higher or lower risk of breast cancer than the other

    (either as a first-time diagnosis or recurrence).

    E n d - o f - L i f e I s s u e s

    Palliative care, which provides physical, emotional, and

    spiritual relief, must be provided with attempts for curative

    therapy and becomes the exclusive goal when cure cannot be

    expected. At all stages of breast cancer, treatment needs to

    be modified for life expectancy.

    For patients with metastatic disease for which cure is

    not attainable, the physician should clarify the goals of

    care through frequent, clear discussions with the patientand, when appropriate, the family. All should recognize that

    cognitive impairment alone does not exclude the patient from

    participating in decision making, because some patients with

    impaired cognition are able to understand, explain the

    consequences of, and voice an opinion about certain treatment

    options.

    Pain from bony metastases should be treated as described

    above with nonsteroidal anti-inflammatory drugs, pamidronate,

    local radiation, and strontium 89 rather than with opioids if

    possible. Palliative chemotherapy may be useful when the

    tumor invades vital organs.

    C h e m o t h e r a p y

    Chemotherapy is treatment with cancer-killing drugs that may

    be given intravenously (injected into a vein) or by mouth.

    The drugs travel through the bloodstream to reach cancer

    cells in most parts of the body. The chemotherapy is given in

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    cycles, with each period of treatment followed by a recovery

    period. Treatment usually lasts for several months.

    W h e n i s c h e m o t h e r a p y u s e d ?There are several situations in which chemotherapy may be

    recommended.

    Adjuvant chemotherapy: Systemic therapy given to patientsafter surgery who have no evidence of cancer spread is called

    adjuvant therapy. When used as adjuvant therapy after

    breast-conserving surgery or mastectomy, chemotherapy reduces

    the risk of breast cancer coming back. Even in the early

    stages of the disease, cancer cells may break away from the

    primary breast tumor and spread through the bloodstream.

    These cells don't cause symptoms, they don't show up on

    imaging tests, and they can't be felt during a physical exam.

    But if they are allowed to grow, they can establish new

    tumors in other places in the body. The goal of adjuvantchemotherapy is to kill undetected cells that have traveled

    from the breast.

    Neoadjuvant chemotherapy: Chemotherapy given before surgeryis called neoadjuvant therapy. The major benefit of

    neoadjuvant chemotherapy is that it can shrink large cancers

    so that they are small enough to be removed by lumpectomy

    instead of mastectomy. Another possible advantage of

    neoadjuvant chemotherapy is that doctors can see how the

    cancer responds to chemotherapy. If the tumor does not

    shrink, your doctor may try different chemotherapy drugs.So far, it's not clear that neoadjuvant chemotherapy improves

    survival, but it seems to be at least as effective as

    adjuvant therapy after surgery.

    Chemotherapy for advanced breast cancer: Chemotherapy canalso be used as the main treatment for women whose cancer has

    already spread outside the breast and underarm area at the

    time it is diagnosed, or if it spreads after initial

    treatments. The length of treatment depends on whether the

    cancer shrinks, how much it shrinks, and how a woman tolerates

    length of treatment. Some of the most common possible sideeffects include:

    hair loss

    mouth sores

    loss of appetite

    nausea and vomiting

    increased chance of infections (due to low white blood cell

    counts)

    easy bruising or bleeding (due to low blood platelet counts)

    fatigue (due to low red blood cell counts and other reasons)

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    D E F I N I T I O N O F T E R M S

    B r e a s t c a n c e r g e n e r a l t e r m s

    It is important to understand some of the key words used todescribe breast cancer.

    CarcinomaThis is a term used to describe a cancer that begins in

    the lining layer (epithelial cells) of

    organs such as the breast. Nearly all breast cancers are

    carcinomas (either ductal carcinomas or lobular carcinomas).

    AdenocarcinomaIs a type of carcinoma that starts in glandular tissue

    (tissue that makes and secretes a substance). The ducts andlobules of the breast are glandular tissue (they make breast

    milk), so cancers starting in these areas are sometimes

    called adenocarcinomas.

    Carcinoma in situThis term is used for the early stage of cancer, when it

    is confined to the layer of cells where it began. In breast

    cancer, in situ means that the cancer cells remain confined

    to ducts (ductal carcinoma in situ) or lobules (lobular

    carcinoma in situ). They have not invaded into deeper

    tissues in the breast or spread to other organs in the body,

    and are sometimes referred to as non-invasive breast cancers.

    Invasive (infiltrating) carcinomaAn invasive cancer is one that has already grown beyond

    the layer of cells where it started(as opposed to carcinoma

    in situ). Most breast cancers are invasive carcinomas either

    invasive ductal carcinoma or invasive lobular carcinoma.

    SarcomaSarcomas are cancers that start from connective tissues

    such as muscle tissue, fat tissue, or blood vessels. Sarcomas

    of the breast are rare.

    Triple-negative breast cancerThis term is used to describe breast cancers (usually

    invasive ductal carcinomas) whose cells lack estrogen

    receptors and progesterone receptors. Breast cancers with

    these characteristics tend to occur more often in younger

    women and in African-American women, and they tend to grow

    and spread more quickly than most other types of breast

    cancer. Because the tumor cells lack these receptors, neither

    hormone therapy nor drugs that target HER2 are effective

    against these cancers (although chemotherapy may be useful ifneeded).

    Mixed tumorsMixed tumors are those that contain a variety of cell

    types, such as invasive ductal cancer combined with invasive

    lobular breast cancer. In this situation, the tumor is

    treated as if it were an invasive ductal cancer.

    Medullary carcinomaThis special type of infiltrating breast cancer has a

    rather well defined boundary between tumor tissue and normaltissue. It also has some other special features, including

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    the large size of the cancer cells and the presence of immune

    system cells at the edges of the tumor. Medullary carcinoma

    accounts for about 3% to 5% of breast cancers. The outlook

    (prognosis) for this kind of breast cancer is generally

    better than for the more common types of invasive breast

    cancer. Most cancer specialists think that true medullary

    cancer is very rare, and that cancers that are called

    medullary cancer should be treated as the usual invasive

    ductal breast cancer.

    Metaplastic carcinomaIs a very rare type of invasive ductal cancer. These

    tumors include cells that are normally not found in the

    breast, such as cells that look like skin cells (squamous

    cells) or cells that make bone. These tumors are treated like

    invasive ductal cancer.

    Mucinous carcinomaAlso known as colloid carcinoma, this rare type of

    invasive breast cancer is formed by mucus-producing cancer

    cells. The prognosis for mucinous carcinoma is usually better

    than for the more common types of invasive breast cancer.

    Paget disease of the nippleThis type of breast cancer starts in the breast ducts

    and spreads to the skin of the nipple and then to the areola,

    the dark circle around the nipple. It is rare, accounting for

    only about 1% of all cases of breast cancer. The skin of the

    nipple and areola often appears crusted, scaly, and red, withareas of bleeding or oozing. The woman may notice burning or

    itching.

    Paget disease is almost always associated with either

    ductal carcinoma in situ (DCIS) or, more often, with

    infiltrating ductal carcinoma. If no lump can be felt in the

    breast tissue and the biopsy shows DCIS but no invasive

    cancer, the prognosis is excellent.

    Tubular carcinoma

    Tubular carcinomas are another special type of invasiveductal breast carcinoma. They are called tubular because of

    the way the cells are arranged when seen under the

    microscope. Tubular carcinomas account for about 2% of all

    breast cancers and tend to have a better prognosis than most

    other infiltrating ductal or lobular carcinomas.

    Papillary carcinomaThe cells of these cancers tend to be arranged in small,

    finger-like projections when viewed under the microscope.

    These cancers are most often considered to be a subtype of

    ductal carcinoma in situ (DCIS), and are treated as such. Inrare cases they are invasive, in which case they are treated

    like invasive ductal carcinoma, although the outlook is

    likely to be better. These cancers tend to be diagnosed in

    older women, and they make up no more than 1% or 2% of all

    breast cancers.

    Adenoid cystic carcinoma (adenocystic carcinoma)These cancers have both glandular (adenoid) and

    cylinder-like (cystic) features when seen under the

    microscope. They make up less than 1% of breast cancers. They

    rarely spread to the lymph nodes or distant areas, and

    they tend to have a very good prognosis.

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    Phyllodes tumorThis very rare breast tumor develops in the stroma

    (connective tissue) of the breast, in contrast to carcinomas,

    which develop in the ducts or lobules. Other names for these

    tumors include phylloides tumorand cystosarcoma phyllodes.

    These tumors are usually benign but on rare occasions may be

    malignant. Benign phyllodes tumors are treated by removing

    the mass along with a margin of normal breast tissue. A

    malignant phyllodes tumor is treated by removing it along

    with a wider margin of normal tissue, or by mastectomy. While

    surgery is often all that is needed, these cancers may not

    respond as well to the other treatments used for invasive

    ductal or lobular breast cancer.

    AngiosarcomaThis is a form of cancer that starts from cells that

    line blood vessels or lymph vessels. It rarely occurs in the

    breasts. When it does, it is usually seen as a complicationof radiation to the breast. It tends to develop about 5 to 10

    years after radiation treatment. However, this is an

    extremely rare complication of breast radiation therapy.

    Angiosarcoma can also occur in the arm of women who develop

    lymphedema as a result of lymph node surgery or radiation

    therapy to treat breast cancer. These cancers tend to grow

    and spread quickly. Treatment is generally the same as for

    other sarcomas.

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    B I B L I O G R A P H Y

    Huether, S.E., McCance K.L., (2004). Understanding Pathophysiology

    3rd edition. USA: Mosby

    Doenges, M E., Moorehouse, M.F., (2002). Nursing Care Plans:

    Guidelines for individualizing patient cares 6th edition.

    Philadelphia USA: Davis company

    Lee, E.C., Banasik, J., (2005). Pathophysiology 3rd edition.

    Philippines: Elsevier Saunders

    Lemone, P., Burke, K., (2004). Medical-surgical Nursing: Critical

    Thinking in Client Care 3

    rd

    edition. USA: Pearson

    Schilling, J.A., Kelly, W.J., et al (2007). Nursing Drug Handbook

    27th edition. Philippines: Lippincott William and Wilkins.

    Smeltzer, S.C., Bare, B.G., Hinkle, J.L., and Cheever, K.H. (2008).

    Brunner and Suddarths Textbook of Medical-Surgical Nursing 11th

    edition. Philippines: Lippincott Williams and Wilkins.


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