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CURRICULUM VITAE Henry J. Silverman, MD, MA (Philosophy) July 2011 Professor of Medicine The University of Maryland School of Medicine Division of Pulmonary and Critical Care Medicine 110 South Paca Street, 2 nd Floor Baltimore, Maryland 21201 E-mail: [email protected] Cell: 443.562.5143 EDUCATION B.S. 1974 Biomedical Engineering Rensselaer Polytechnic Institute Troy, New York M.S. 1974 Biomedical Engineering Rensselaer Polytechnic Institute Troy, New York M.D. 1978 Johns Hopkins School of Medicine Baltimore, Maryland Internship 1979 Baltimore City Hospital (Medicine) Baltimore, Maryland Residency 1981 Baltimore City Hospital (Medicine) Baltimore, Maryland Fellowship 1983 Johns Hopkins Hospital (Pulmonary Medicine) Baltimore, Maryland M.A. Bioethics 1995 Department of Philosophy Georgetown University, Washington D.C. 1
Transcript

CURRICULUM VITAE

Henry J. Silverman, MD, MA (Philosophy) July 2011Professor of MedicineThe University of Maryland School of MedicineDivision of Pulmonary and Critical Care Medicine110 South Paca Street, 2nd FloorBaltimore, Maryland 21201E-mail: [email protected]: 443.562.5143

EDUCATION

B.S. 1974 Biomedical EngineeringRensselaer Polytechnic InstituteTroy, New York

M.S. 1974 Biomedical EngineeringRensselaer Polytechnic Institute

Troy, New York

M.D. 1978 Johns Hopkins School of Medicine Baltimore, Maryland

Internship 1979 Baltimore City Hospital (Medicine) Baltimore, Maryland

Residency 1981 Baltimore City Hospital (Medicine) Baltimore, Maryland

Fellowship 1983 Johns Hopkins Hospital (Pulmonary Medicine) Baltimore, Maryland

M.A. Bioethics 1995 Department of Philosophy Georgetown University, Washington D.C.

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MAJOR ACADEMIC TASKS

6/83 – present Attending, Pulmonary & Critical Care

6/90 - present Chair, Ethical Advisory Committee University of Maryland Hospital Baltimore, Maryland

7/83 - 2001 Director of Medical Intensive Care Unit University of Maryland School of Medicine Baltimore, Maryland

1/85 - 6/97 Director of Fellowship Program University of Maryland School of Medicine Baltimore, Maryland

8/84 - 6/85 Acting Chief, Pulmonary Division University of Maryland School of Medicine Baltimore, Maryland

MAJOR RESEARCH INTERESTS Research Ethics/International Research Ethics End-of-Life/Advance Directives/Palliative Care/Professionalism/Humanism

Critical Care Acute Respiratory Distress Syndrome/Sepsis

CERTIFICATIONS American Board of Internal Medicine #79628

Pulmonary Subspecialty #79628 Critical Care Medicine #79628

LICENSUREMaryland #D22643

PROFESSIONAL MEMBERSHIPS 1993 Member, Kennedy Institute of Ethics 1993 Member, American Society for Bioethics and Humanities 1984 Member, Baltimore Critical Care Society 1984 Member, Maryland Lung Association 1985 Member, Society of Critical Care Medicine 1986 Fellow, American College of Chest Physicians

1987 Member, American Thoracic Society

HONORS/AWARDS

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6/01 Senior Medical Students2001 Humanism in Medicine AwardThe Healthcare Foundation of New Jersey

6/88 Senior Residents' Award for Teaching University of Maryland

EDITORIAL TASKS Mid-Atlantic Ethics Committee Newsletter: Contributing EditorThe Journal of Clinical Ethics: ReviewerThe Journal of Law, Medicine & Ethics: ReviewerJAMA: ReviewerCritical Care Medicine Journal: ReviewerChest Journal: ReviewerNew England Journal of Medicine: Reviewer

COMMITTEE ACTIVITIES - (Outside the University)1996 – 2005 Chair, Ethics Subcommittee, NIH ARDS Clinical Trials Network1999 - present Alpha One Foundation Medical and Scientific Advisory Committee, Member1996 - present Advisory Board, Baltimore Area Ethics Committee Network1998 - 2002 Chair, Genetics, Ethics, Psychosocial and Economics Writing Group, Joint

American Thoracic Society - European Respiratory Society Task Force for the Diagnosis and Management of Alpha 1 – Antitrypsin Deficiency.

1997 - 2002 Advisory Board, Office of the Attorney General’s Project on Care at the End of Life.

1995 - 1997 Director, Strengthening Healthcare Ethics Committees Outreach Program1995 - 1996 State of Maryland’s Work Group on Privacy and Confidentiality1992 - 1995 Co-Director, Maryland Ethics Committee Network1992 – 1996 Advisory Board, Certificate Program in Bioethics, Loyola College, Balt. MD 1992 - 1996 Ethics Committee, Society of Critical Care Medicine1991 - 1995 Professional Ethics Committee, State Medical Society1990 – 1994 President, Baltimore Critical Care Society1994 - 1995 Health Care Policy and Clinical Practice Committee, American Thoracic

Society1991 Program Committee - Patient Self-Determination Act, October 28, l991 -

School of Law, University of Maryland1990 Program Committee - Ethics Committee, June 25, 1990, School of Law,

University of Maryland1988 – 1990 Secretary/Treasurer, Baltimore Critical Care Medicine Society1992 Program Committee, American College of Chest Physicians, October, l9921989 - 1991 Chairman, Professional Educational Committee, American Lung Association1986 - 1993 Awards and Grants Committee, American Lung Association1986 - 1987 Nominating Committee, Maryland Thoracic Society1986 – 1987 Program Committee, 27th Scientific Session, MD Thoracic Society1985 - 1986 Program Committee, 26th Scientific Session, Maryland Thoracic SocietyRESEARCH ETHICS ACTIVITIES

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Training Programs

2004 – Present Program Director: Middle East Research Ethics Training Initiative (MERETI)Sponsored by Fogarty International Center/NIH

Member, Research Ethics Committees 2001- present Ad Hoc Reviewer, University of Maryland School of Medicine IRB2002 – present Member, Chesapeake Research Review, Inc. 1995 – 2005 Chair, Research Ethics Committee; NIH-sponsored ARDS Network Clinical

Trials Groups2003 – present Member, Maryland Medical Research Institute

Organizer/Presenter:Workshops/Conference in Research Ethics (International)1/10-1/13/2007 Research Ethics Workshop, Amman, Jordan. Sponsored by EMRO/WHO1/15- 1/18/2007 Research Ethics Workshop, Khartoum, Sudan Sponsored by EMRO/WHO12/11-12/14/2007 Research Ethics Workshop, Muscat, Oman Sponsored by EMRO/WHOMay 14, 2007 National Bioethics Committees, Cairo, Egypt Sponsored by EMRO/WHO and

UNESCOAugust 11, 2008 Research Ethics Training, Cairo, Egypt EMRO/WHOAugust 12-14, 2008 First Meeting for the Eastern Mediterranean and Arab Forum on Research

Ethics, Cairo, Egypt. January 2009 3-day Workshop in Research Ethics and GCP, Cairo, Egypt (Cairo

University, Theodur Bilharz Research Institute, and National Cancer Institute).

July 31, 2010 One day training for IRBs in Jordan: Sponsored by The Jordanian Association of Pharmaceutical Manufacturers (JAPM) and USAID

1/21-24/2011 3-day workshop in research ethics, Jizan University, Saudi Arabia

Data Safety Monitoring Board (DSMB)5/2006 – present: Member, DSMB: EASE™ Study: randomized, double-blind multi-center study to

evaluate the safety and effectiveness of the Exhale® Drug-Eluting Stent to improve pulmonary function for emphysema subjects with severe hyperinflation

6/2000 – present: Chair, DSMB: NIH Center for Alternative Medicine Research of Arthritis at the University of Maryland School of Medicine

1/94- 6/98: Member, DSMB: Cutter Biologicals: Double-Blind Placebo Controlled, Randomized Multi-center Study of the Safety and Efficacy of TNF MAb in Patients With Septic Shock

8/97 – 6/98: Member, DSMB: PPD Development 6/96 – 4/98: Member, DSMB: Cutter-Wallace Laboratories

Human Research Protection Accreditation Program2005 – present AAHRP – site surveyor2001 – 2005 NCQA Human Research Protection Program - Site Surveyor

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CAMPUS Committee Activities01/96 - 2002 Advisor, Master’s in Applied and Professional Ethics Program01/93 - 1997 Member, Steering Committee, Biomedical Ethics Center01/93 - present Post-Graduate Medical Education Committee07/90 - present Medical Executive Committee07/90 - present Chair, Ethical Advisory Committee01/87 - present Medicine Physician-Nursing Council Committee11/92 - 09/94 Impaired Medical Staff Committee10/86 - 09/93 Malpractice Committee07/86 - 09/93 Quality Assurance Committee06/87 - 06/90 ICU Planning Committee09/86 - 06/88 Alternate member, School of Medicine Council10/84 - 01/86 Group Practice Committee07/84 - 11/90 Medical Consultant, COPD Rehabilitation Program07/84 - 01/85 Member, Medical Board07/83 - 09/84 Member, Intensive Care Unit Quality Assurance Committee

TEACHING ACTIVITIESBasic Science:1992 - present Lecture on Lung Sounds

Sophomore Medical Students l983 - present Housestaff Morbidity and Mortality Conferences1986 - 1993 Lecture on Interstitial Lung Disease

Sophomore Medical Students l987 - 1993 Residents' Journal Club l983 - 1995 Lecture on Acute Respiratory Failure

Junior Medical Students1987 – 1994 Respiratory Physiology Course

Freshman Medical Students

Medical Ethics:1996 - 2003 Medicine & Literature (required course)

Component of Introduction to Clinical Practice Course1997 - 1998 Philosophy of Medicine Through Literature,

Graduate School Course, 3 Credits, MAPE 6011994 - present Ethics Curriculum - Medicine Housestaff1994 - present Medical Humanities Hour

Monthly Forum for the Staff of the University of Maryland Medical System1993 - present Junior Medical Student Case Discussions in Ethics

Monthly discussions of medical ethics cases with junior medical students1996 - 1998 Facilitator, Introduction to Clinical Practice Course (ICP), Freshmen Medical

Students1995 - 1996 Facilitator, Problem-Based Learning Course (PBL)

Freshmen/Sophomore Medical Students1989 – present Legal Issues in Health Care - University of Maryland Law School1997 - 1998 Small Discussion Group Leader, Intensive Bioethics Course - Kennedy

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Institute of Ethics, Georgetown University1995 Medical Ethics in Nursing - Towson State University, 3-credit Summer Course1993 - 1996 Health Care Ethics: Issues and Applications.

Ten-week bioethics course for health care providers - Loyola College1994 - 1995 Freshman Medical Student Selective:

Biweekly discussions of medical ethics cases 1992 - 1993 Sophomore Medical Student Elective: Cognitive and Humanistic Dimensions

in Medical Ethical Decision making"1991 - 1992 Ethics Seminar: Junior Medical Students1991 – 1993 Discussion Group Leader: Sophomore Medicine Ethics Course1991 – 1993 "Decisions Near the End of Life" Program - Hospital-wide ethics educational

program

GRANT SUPPORTPresent:2R25 TW007090-5A1: Fogarty International Center/NIHProject Title: Middle East Research Ethics Training Initiative (MERETI)Principal Investigator: SILVERMAN, HENRY J MD 20%Dates: 06/01/2011 – 5/31/2016; Amount: Total Costs: $1,250,000

3R25TW007090-04S3: Fogarty International Center/NIHTitle: Information and Communication Technology (ICT), Administrative SupplementPrincipal Investigator: Silverman, Henry JDates: 10/1/09 – 9/30/2011

Previous1 R25 TW007090-01: Fogarty International Center/NIHProject Title: International Research Bioethics Training Program: EgyptPrincipal Investigator: SILVERMAN, HENRY J MD 25%Dates: 09/03/04 – 6/30/08; Amount: Total Costs: $938,197

National Heart, Lung, and Blood Institute (NHLBI): Clinical Center for a Clinical Network for the Treatment of Adult Respiratory Distress Syndrome. Principal Investigator;Dates: 10/1994 - present; Amount: Total Costs: $883,540; Direct Costs: $799,001; Indirect Costs: $84,539.

R25 CA66940: National Institutes of HealthHospice Educational Program for the School of Medicine. Co-Investigator. 10% Salary Support

Southern Medical Association: "Regulation of Beta Receptors in Patients with Septic Shock". Ruben Penaranda, Principal Investigator; Henry J. Silverman, Clinical Advisor. Dates: 7/88-6/89; Amount: $2,500.

Southern Medical Association: "Myocardial Dysfunction in Septic Shock”. John Orens, Principal Investigator; Henry J. Silverman, Clinical Advisor. Dates: 7/89-6/90; Amount: $2,500.

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Maryland Lung Association Grant: "Regulation of Beta Receptors in Canine Endotoxin Shock". Principal Investigator. Dates: 7/86-12/88; Amount: $35,000

PUBLICATIONSA. Thesis Dissertation:1. Silverman HJ. Plasma protein kinetics after hemorrhage and resuscitation with crystalloid

solutions. Master Thesis. Rensselaer Polytechnic Institute, 1974.

B. Refereed Journal Articles: 1. Silverman HJ, Haponik EF, Van Hook C. Hemodynamic changes in human anaphylaxis.

Am J of Med 1984; 76:341-344.

2. Rock P, Silverman HJ, Plump D, Zenon K, Michael J, Summer W. Naloxone does not increase mean arterial blood pressure in patients with septic shock. Crit Care Med 1985; 13:28-35.

3. Silverman HJ, Haponik EF. Pulsus paradoxus in pulmonary embolism. Crit Care Med 1986; 14:165-166.

4. Silverman HJ, Taylor WR, Smith PL, Lichtenstein L, Sobotka A, Bleecker ER. Prevention of antigen shock by Isoproterenol in an in vivo canine model. Am Rev Respir Dis 1986; 134:243-247.

5. Silverman HJ, Eppler J, Pitman AP, Patz D. Pulmonary artery wedge pressure measurements in patients on assisted ventilation. J Crit Care 1987; 2:115-120.

6. Silverman HJ, Taylor WR, Smith PL, Lichtenstein L, Sobotka A, Bleecker ER. Effects of antihistamines on the cardiopulmonary changes due to canine anaphylaxis. J Appl Physiol 1988; 64:210-217.

7. Oken H, Silverman HJ. Shortness of breath and chest pain in a 38-year old woman with a history of breast cancer. Hospital Physician 1988; 24:49-56.

8. Silverman HJ, Abrams J, Rubin LJ. Effects of Interleukin-2 on oxygen delivery and consumption in patients with advanced malignancy. Chest 1988; 94:816-821.

9. Panos RJ, Barr LF, Walsh TJ, Silverman HJ. Factors associated with fatal hemoptysis in cancer patients. Chest 1988; 94:1008-1013.

10. Silverman HJ, Haponik EF. Thorotrastoma with massive hemoptysis. Hospital Physician 1989; 25:25-28.

11. Nora R, Abrams JS, Tait NS, Hiponia D, Silverman HJ. Myocardial toxicity during recombinant interleukin-2 therapy. J Nat'l Cancer Institute 1989; 81:59-63.

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12. Bone RC, Slotman G, Maunder R, Silverman H, Hyers T, Kerstein M, Ursprung JJ and the Prostaglandin E1 Study Group. Randomized double blind, multi-center study of Prostaglandin E1 in patients with the adult respiratory distress syndrome. Chest 1989; 96:114-119.

13. Bone RC, Maunder R, Slotman G, Silverman HJ, Hyers TM, Kerstein MD, Ursprung JJ, and the Prostaglandin E1 Study Group. An early test of survival in patient with the adult respiratory distress syndrome. The PaO2/FIO2 ratio and its differential response to conventional therapy. Chest 1989; 96:849-851.

14. Silverman HJ, Slotman G, Bone RC, Maunder R, Hyers, TM, Kerstein MD, Ursprung JJ, and the Prostaglandin E1 Study Group. Effects of prostaglandin E1 on oxygen delivery and consumption in patients with the adult respiratory distress syndrome. Chest 1990; 98:405-410.

15. Silverman HJ, Lee NH, El-Faakahany EE. Effects of canine endotoxin shock on lymphocytic beta-adrenergic receptors. Circulatory Shock 1990; 32:392-306.

16. Silverman HJ. Lack of a relationship between induced changes in lactate levels. Chest 1991; 100:1013-1015.

17. Silverman HJ. Gastric tonometry: An index of splanchnic tissue oxygenation? Crit Care Med 1991; 19:1223-4.

18. Bone RC, Balk R, Slotman G, Maunder R, Silverman HJ, Hyers T, Kerstein M and the prostaglandin E1 study group. The adult respiratory distress syndrome: A manifestation of a systemic disease. Chest. 1992; 101:320-330.

19. Silverman HJ, Vinicky JK, Gasner MR. Advance directives: implications for critical care. Crit Care Med 1992; 20:1027-1031.

20. Silverman HJ, Tuma P. Gastric tonometry in septic patients: Effects of dobutamine infusions and packed red blood cell transfusions. Chest 1992; 102:184-188.

21. Silverman HJ. Deciding when to discuss or provide cardiopulmonary resuscitation. J Crit Care 1992; 7:129-135.

22. Slotman GJ, Kerstein MD, Bone RC, Silverman HJ, Maunder R, Hyers TM, Ursprung JJ and the prostaglandin E1 study group. The effects of prostaglandin E1 on non-pulmonary organ function during clinical acute respiratory failure. Journal of Trauma. 1992; 32:1-10.

23. Martin MA, Silverman HJ. Gram-negative sepsis and the adult respiratory distress syndrome. Clinical Infectious Disease 1992; 14:1213-1228.

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24. Silverman HJ, Penaranda R, Orens J, Lee NH. Evidence of myocardial beta-adrenergic desensitization in septic patients. Crit Care Med 1993; 21:31-39.

25. Silverman HJ, Fry ST, Armistead N. Nurses' perspectives on implementation of the Patient Self-Determination Act. Journal of Clinical Ethics 1994; 5:30-37.

26. Society of Critical Care Medicine Ethics Committee. Consensus statement on the triage of critically ill patients. JAMA l994; 271:1200-1203.

27. Silverman, HJ. Revitalizing a hospital ethics committee. HEC Forum 1994; 6:189-222.

28. Weg JG, Balk RA, Tharatt RS, Jenkinson SG, Shah JB, Zaccardelli D, et al. and the Exosurf ARDS Sepsis Study Group. Safety and potential efficacy of an aerosolized surfactant in human sepsis-induced adult respiratory distress syndrome. JAMA 1994; 272:1433-1438.

29. Silverman HJ, Tuma P, Schaeffer M, Singh B. Implementation of the Patient Self-Determination Act in a hospital setting: An initial evaluation. Arch Intern Med 1995; 155:502-510.

30. Abraham E, Wunderink R, Silverman HJ, et.al. Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. JAMA 1995; 273:934-941.

31. Travaline JM, Silverman HJ. Discussions with outpatients with chronic obstructive pulmonary disease regarding mechanical ventilation as life-sustaining therapy. Southern Med J l995; 88:1034-1038.

32. Silverman HJ. How decisive are physician values in end-of-life decision-making? Crit Care Med 1996; 24:909-910.

33. Silverman HJ. Ethical considerations of ensuring an informed and autonomous consent in research involving critically ill patients. Amer J of Respir and Crit Care Med 1996; 154:582-86.

34. Silverman HJ, Lanken PN. Advance Directives: Are they fulfilling their purpose? Current Opinion in Critical Care 1996; 2:337-343.

35. Silverman HJ. The role of emotions in decisional competence, standards of competency and altruistic acts. The Journal of Clinical Ethics 1997; 8:170-175.

36. Khanna V, Silverman H, Schwartz J. Disclosure of Operating Practices By Managed Care Organizations to Consumers of Health Care: Obligations of Informed Consent. The Journal of Clinical Ethics 1998; 9:291-296.

37. Silverman HJ. Description of an ethics curriculum for a medicine residency program. Western Journal of Medicine 1999; 170:228-231.

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38. The Acute Respiratory Distress Syndrome Network. Ketoconazole for Early Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome. A Randomized Controlled Trial. JAMA. 2000; 283:1995-2002

39. The Acute Respiratory Distress Syndrome Network. Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome. N Engl J Med. 2000; 342:1301-8.

40. Silverman, HJ. Organizational Ethics in Health Care Organizations: Proactively Managing the Ethical Climate To Ensure Organizational Integrity. HEC Forum. 2000; 12:202-215.

41. Silverman HJ, Hull S, Sugarman J. Degree of variability among institutional review boards on approved research practices and informed consent in the context of a multi-center clinical trial. Critical Care Medicine. 2001; 29:235-241.

42. DeRenzo E, Silverman HJ, Hoffmann D, Schwartz J. Maryland’s Ethics Committee Legislation: A Leading Edge Model or A Step Into The Abyss. HEC Forum. 2001; 13:49-58.

43. Kallet RH, Corral W, Silverman JH, Luce JM. Implementation of a low tidal volume ventilation protocol for patients with acute lung injury or acute respiratory distress syndrome. Respir Care 2001; 46(10): 1024-1037.

44. The Acute Respiratory Distress Syndrome Clinical Trials Network. Randomized, placebo-controlled trial of lisofylline for early treatment of acute injury and acute respiratory distresssyndrome. Crit Care Med 2002; 30:1-6.

45. Silverman HJ. Symptom management in the intensive care unit: toward a more holistic approach. Crit Care Med. 2002; 30(4):936-7.

46. Tarzian A, Silverman HJ. Care Coordination and Utilization Review: Clinical Case Managers’ Perceptions of Dual Role Obligations. Journal of Clinical Ethics. 2002; 13:216-229.

47. ATS Alpha-1-Antitrypsin Deficiency Task Force. American Thoracic Society/European Respiratory Society Statement: Standards for the Diagnosis and Management of Individuals with Alpha-1 Antitrypsin Deficiency. Silverman HJ. Chair: Genetic Testing for Alpha-1 Antitrypsin Deficiency: Genetics, Psychosocial, Ethics, and Economics Issues. Am J Resp Crit Care Med. 2003; 168:818-900.

48. Silverman HJ, Luce JM, Schwartz J. Protecting Decisionally Impaired Subjects In Research:

The Need For A Multifaceted Approach. Am J Resp Crit Care Med. 2004; 169:10-14.

49. Miller FG, Silverman HJ. The Ethical Relevance of the Standard of Care in the Design of Clinical Trials. Am J Resp Crit Care Med. 2004; 169:562-564.

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50. Silverman HJ, Miller FG. Control Group Selection in Critical Care Randomized Controlled Trials Evaluating Interventional Strategies: An Ethical Assessment. Crit Care Med. 2004; 32:852-857.

51. Silverman HJ, Druml C, Lemaire F, Nelson R. The European Union Directive and theprotection of incapacitated subjects in research: an ethical analysis. Intensive Care Medicine. 2004; 9:1723-1729.

52. Ross DD, Shpritz D, Alexander CS, Carter K, Edelman MJ, Friedley N, Hemani A, Keay TJ, Roy SC, Silverman HJ, Tasker DJ, Timmel D, Schwartz J, Wolfsthal SD. Development of Required Postgraduate Palliative Care Training for Internal Medicine Residents and Medical Oncology Fellows. J Cancer Edu. 2004; 19:81-87.

53. Silverman HJ. The Acute Respiratory Distress Syndrome Network controversy: lessons and legacy. Current Opinion in Critical Care 2004; 10:560-564.

54. Silverman HJ. Withdrawal of feeding-tubes from incompetent patients: the Terri Schiavo case raises new issues regarding who decides in end-of-life decision making. Intensive Care Medicine. 2005; 31:480-1.

55. Silverman HJ, Luce JM, Lanken PN, Morris AH, Harabin AL, Oldmixon CF, Thompson BT, Bernard GR, for the NHLBI Acute Respiratory Distress Syndrome Clinical Trials Network. Recommendations for informed consent forms for critical care clinical trials. Crit Care Med. 2005; 33:867-82.

56. Silverman HJ. Enhancing research ethics capacity: implications for protection of research subjects, avoiding exploitation and achieving global health. Middle East Fertility Society Journal. 2005; 10:105-109.

57. Silverman HJ, Lemaire F. Ethics and Critical Care Research. Intensive Care Medicine. 2006; 32: 1697-705

58. Silverman, HJ, et.al. HRETIE 2005 Candidates and Faculty. Enhancing Research Ethics Committees In Egypt. Guidelines for Standard Operating Procedures. The Monitor. 2006; 20:49.

59. Khalil SS, Silverman HJ, Raafat M, El-Kamary S, El-Setouhy M. Attitudes, understanding, and concerns regarding medical research amongst Egyptians: a qualitative pilot study. BMC Med Ethics. 2007 Aug 29;8:9.

60. Ramahi I, Silverman H. CLINICAL RESEARCH LAW IN JORDAN: AN ETHICAL ANALYSIS. Dev World Bioeth. 2007, Dec. 12.

61. Abdur Rab M, Afzal M, Abou-Zeid A, Silverman H. Ethical practices for health research in the Eastern Mediterranean region of the World Health Organization: a retrospective data

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analysis. PLoS ONE. 2008 May 7;3(5):e2094

62. Abou-Zeid A, Afzal M, Silverman H. Capacity Mapping of the National Bioethics Committees in the Eastern Mediterranean Region. BMC Med Ethics. 2009 Jul 4;10:8

63. Kassem HS, Rab F, Abouzeid A, Silverman H. Beyond research ethics committees: acceptance by investigators and involvement of the community. Middle East Fertility Society Journal. 2009;14:1.

64. Wazaify M, Khalil SS, Silverman HJ. Expression of therapeutic misconception amongst Egyptians: A qualitative pilot study. BMC Med Ethics. 2009 Jun 30;10:7

65. Silverman H, Ahmed B, Ajeilat S, Al-Fadil S, Al-Amad S, El-Dessouky H, El-Gendy I, El-Guindi M, El-Nimeiri M, Muzaffar R, Saleh A. Curriculum Guide for Research Ethics Workshops for Countries in the Middle East. Dev World Bioeth. 2009 Aug18

66. Abou-Zeid A, Silverman HJ, Shehata M, et.al. Collection, Storage, and Use of Blood Samples for Future Research: HJViews of Egyptian Patients Expressed in a Cross-Sectional Survey. J Med Ethics. 2010 Sep;36(9):539-47. Epub 2010 Jul 26.

67. Sleem H, El-Kamary SS, Silverman HJ. Identifying structures, processes, resources and needs of research ethics committees in Egypt. BMC Med Ethics. 2010 Jun 28;11:12.

68. Riyami AA, Jaju D, Jaju S, Silverman HJ. The Adequacy of Informed Consent Forms in Genetic Research Performed in Oman: A Pilot Study. Dev World Bioeth. 2011 Jan 25. doi: 10.1111/j.1471-8847.2010.00293.

69. Sleem H, Abdelhai RA, Al-Abdallat I, Al-Naif M, Gabr HM, Kehil ET, Sadiq BB, Yousri R, Elsayed D, Sulaiman S, Silverman H. Development of an accessible self-assessment tool for research ethics committees in developing countries. J Empir Res Hum Res Ethics. 2010 Sep;5(3):85-96.

70. Silverman HJ. Protecting Vulnerable Research Subjects in Critical Care Trials: Enhancing the Informed Consent Process and Recommendations for Safeguards. Annals of Intensive Care 2011, 1:8 doi:10.1186/2110-5820-1-8. Published: 13 April 2011

71. El-Dessouky HF, Abdel-Aziz AM, Ibrahim C, Malini M, Reham Abul Fadl R, Silverman H. Knowledge, Awareness, and Attitudes about Research Ethics among Dental Faculty in the Middle East: A Pilot Study. International Journal of Dentistry, 2011), Article ID 694759, 13 pagesdoi:10.1155/2011/694759.

C. Non-Refereed Publications

Book Chapters:

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1. Silverman HJ, Gross JY. Preoperative Care of the Pulmonary Patient. In: Wolfstahl S, ed Perioperative Care, 1989.

2. Silverman HJ. Myocardial Dysfunction in Sepsis. In: Vincent JL, ed. Update in Intensive Care and Emergency Medicine, Vol. 10, 1990.

3. Silverman HJ. Pharmacologic Approach to the Pulmonary Patient. In: Pharmacologic Approach to the Critically Ill Patient. (ed) Bart Chernow. Williams & Wilkens, Baltimore, MD. 1994.

4. Silverman HJ. How Should Death Be Defined in the Intensive Care Unit? In: Ethics in Critical Care. (ed) James Orlowski. University Publishing Group, Hagerstown, MD, 1999.

Articles:

1. Silverman HJ, Mendoza J, Rubin LJ. Management of pulmonary hypertension. Drug Therapy 1986;16:57-68.

2. Silverman HJ. Letting Go. Maryland in Baltimore 1989; 3:18.

3. Silverman HJ. Better Way to Decide on Death. Baltimore Sun, July 5, 1990.

4. Vinicky JK, Silverman HJ. Ethics post-Cruzan: Asking hard questions on who shall live and who shall die. Clinician Reviews 1991; 1(1):90-100.

5. Silverman HJ, Vinicky JK. Advanced directives: The living will and durable power of attorney for health care. Clinician Reviews 1991; 1(3):79-93.

6. Vinicky JK, Silverman HJ. The patient's value history. Clinician Reviews 1991; 1(5):73.87.

7. Silverman HJ, Vinicky JK. The debate of assisted suicide and euthanasia. Clinician Reviews 1991; 1(7):67-78.

8. Silverman HJ. Elements of Informed Consent. Clinician Reviews 1992; 2(2): 115-127.

9. Silverman HJ. The debate on assisted suicide and active euthanasia. Health Care Ethics l994; 1:1-4.

10. Silverman HJ. Brain death: A new definition of death? Health Care Ethics l994; 2:1-3.

11. Silverman HJ. What is informed consent? Health Care Ethics l994; 3:1-4.

12. Silverman HJ. Health Care Decisions Act. Health Care Ethics 1994; 4:1-4.

13. Silverman HJ. Lack of an effect of blood transfusion on oxygen consumption. The Journal of Critical Illness 1994; 9:747-8.

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14. Silverman, HJ. Human embryo research. What are appropriate guidelines? Health Care Ethics l994; 5:1-3.

15. Silverman, HJ. Do patients want to make their own medical decisions? Health Care Ethics 1995; 1:1-3.

16. Silverman, HJ. The ethics of DNR orders in the operating room. Health Care Ethics 1995; 2:1-3.

17. Silverman, HJ. Summer reading list in ethics. Health Care Ethics 1995; 3:1-4.

18. Silverman, HJ. Privacy of health data in the information age. Health Care Ethics 1996; 1:1..

19. Silverman HJ. Cardiopulmonary problems in the office: Bronchodilators. Emergency Medicine 1996; 28:99.

20. Silverman HJ. Advance Directives: Are they fulfilling their purpose? Health Care Ethics Newsletter 1996; 2:1-4.

21. Silverman HJ. An introduction to managed care. Health Care Ethics Newsletter 1996; 3:1-4.

22. Silverman HJ. Dying in the hospital - what are the problems? Health Care Ethics Newsletter 1996; 4:1-4.

23. Silverman HJ. New rules for allocating liver transplants. Health Care Ethics 1997; 1:1-4.

24. Silverman HJ. U.S. Supreme Court to rule on physician-assisted suicide. Health Care Ethics 1997; 2:1-4.

Letters to Editor: 1. Rock P, Silverman HJ, Michael J. Naloxone therapy of septic shock. Crit Care Med 1985;

13:876-877.

2. Nora R, Belani C, Silverman HJ, Abrams J. Immunotherapy of advanced cancer. New Engl J Med 1987; 316:275.

3. Silverman HJ. Response to: Must we always use CPR. N Engl J Med 1988; 318:1273.

4. Silverman HJ. Living wills and the terminally ill. Baltimore Sun, Nov. 14, 1988.

5. Silverman HJ. Cruzan Case: The right to die. Baltimore Sun, Dec. 21, 1989.

6. Silverman HJ. Equivocal definitions of sepsis and septic shock. Crit Care Med 1990; 18:1048.

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7. Silverman HJ. Medical vs. Moral. The New York Times, January 31, 1991.

8. Silverman HJ. Response to: Is informed consent always necessary for randomized, controlled trials. N Engl J Med 1999; 341:449.

D. Abstracts

1. Silverman HJ, Taylor WR, Smith PL, Lichtenstein L, Sobotka A, Bleecker ER. Prevention of anaphylactic shock by isoproterenol in an in vivo canine model of anaphylaxis. The Physiologist 1982; 25:307.

2. Silverman HJ, Smith PL, Lichtenstein L, Sobotka A, Bleecker ER. Effects of anti-histamine agents on immunologic and physiologic alterations during canine anaphylaxis. Fed Proc 1982; 41:1134.

3. Taylor WR, Silverman HJ, Wise RA, Permutt S, Smith PL, Bleecker ER. Cardiovascular mechanisms of anaphylactic shock. The Physiologist 1982; 25:307.

4. Taylor WR, Silverman HJ, Wise RA, Permutt S, Smith PL, Bleecker ER. Circulatory mechanisms during anaphylactic shock. Clin Research 1982; 30:679A.

5. Rock P, Silverman HJ, Plump D, Zenon K, Michael J, Smith P, Summer W. Naloxone does not increase mean arterial blood pressure in patients with septic shock. Chest 1983; 84:344.

6. Oken H, Silverman HJ. Hemoptysis: An unusual cause in a young male. American College of Physicians, Second Annual Associates Meeting, Maryland region, May, 1984.

7. Silverman HJ, Eppler J, Pitman AP, Patz D. Measurements of pulmonary capillary wedge pressure from graphic and digital recorders. Chest 1984; 86:335.

8. Panos RJ, Barr LF, Walsh TJ, Silverman HJ. Pulmonary exsanguination in cancer patients. Am Rev Respir Dis 1987; 135:A38.

9. Silverman HJ, Lee NH, Pier K, El-Fakahany E. Regulation of beta-adrenergic receptors in canine endotoxin shock. Am Rev Respir Dis 1987; 135:A114.

10. Silverman HJ, Abrams J, Rubin LJ. Relationship between oxygen consumption and oxygen delivery in patients given Interleukin-2. Am Rev Resp Dis 1987; 135:A213.

11. Bascom R, Albin RJ, Silverman HJ. Increased non-specific airways reactivity following accidental inhalation of chlorine gas. Am Rev Respir Dis 1987; 135:A235.

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12. Rubin LJ, Silverman HJ, Mendoza J. Measurement of right ventricular ejection fraction by thermodilution technique in chronic pulmonary hypertension. Am Rev Respir Dis 1987; 135:A351.

13. Nora R, Abrams J, Silverman HJ. Myocardial Infarction (MI) in patients receiving high dose recombinant Interleukin-2 (RIL2). Proc Am Soc Clin Onc 1987; 6:245.

14. Silverman HJ, Penaranda R, Orens J, Lee N, El-Fakahany EE. Deterioration of the beta-adrenergic receptor complex in human septic shock. Am Rev Resp Dis 1989; 139:A290.

15. Silverman HJ, Penaranda R, Orens J, Lee N, El-Fakahany EE. Deterioration of the beta-adrenergic receptor complex in human septic shock. Crit Care Med. 1989; 17:S155.

16. Silverman HJ. Optimal hemoglobin value in patients with septic shock. The 5th World Congress on Intensive and Critical Care Medicine. 1989; Kyoto, Japan.

17. Travaline JM, Silverman HJ. Discussions with COPD outpatients regarding mechanical ventilation. Chest 1991; 100:78S.

18. Reines HD, Silverman HJ, Hurst J, Warren J, Williams J, Rotello L, Horton J, Pattishall E. Effects of two concentrations of nebulized surfactant (Exosurf) in sepsis-induced adult respiratory distress syndrome (ARDS). Crit Care Med. 1992; 20:S61.

19. Thurm CA, Silverman HJ. Prognostic value of gastric intramucosal pH in medical intensive care unit patients. Amer Rev Resp Dis 1993; 147:A150.

20. Silverman HJ, Tuma P, Caracci L, Armistead N, Roahen S. Patient Self-Determination Act: Effects on patients' awareness, knowledge, and discussions concerning advance directives. Amer Rev Resp Dis. 1993; 147:A49.

21. Silverman HJ, Tuma P, Caracci L, Armistead N, Roahen S. Patients' reactions and behavior towards implementation of the Patient Self-Determination Act. Crit Care Med. 1993; 21:S220.

22. Wherry J, Wenzel R, Abraham E, Allred R, Balk R, Bone R, Levy H, Nasraway S, Perl T, Silverman H, Wunderink R. A controlled randomized double blind clinical trial of monoclonal antibody to human tumor necrosis factor in patients with sepsis syndrome. Presented at ACCP, Orlando, Florida. October, 1993.

23. Wherry J, Wenzel R, Wunderink R, Silverman H, Perl T, Nasraway S. et al. Monoclonal antibody to human tumor necrosis factor (TNF Mab): multicenter efficacy and safety study in patients with the sepsis syndrome. Presented at the 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, New Orleans, Louisiana, 17-20 October l993, Abstract #696:246.

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24. Babin J, Silverman H. The use of external cooling devices on patients with true fevers. Presented at Greater Washington Area Chapter of the American Association of Critical Care Nurses. September 1993

25. Silverman HJ. Sepsis and the Adult Respiratory Distress Syndrome (ARDS). Shock, 1995; 3:4.

26. Silverman HJ, Hull SC, Sugarman J. Degree of Variability Among Institutional Review Boards (IRBs) on Approved Research Practices and Informed Consnet (IC) Forms: A Case Study of A NIH-Sponsored Multi-Center ARDS Clinical Trial. Respiratory and Critical Care Medicine. 1999; 159:A916.

27. DeRenzo E, Hoffmann D, Schwartz J, Silverman HJ. Maryland’s Ethics Committee Legislation: A Leading Edge Model or A Step Into The Abyss. Presented at the 2nd Annual American Society for Bioethics and Humanities, October 28-31, 1999.

27. Silverman HJ, Tarzian A. Perceptions of Clinical Case Managers in a Tertiary Care Hospital: Combining Discharge Planning with Insurers’ Reimbursement Practices. Presented at the 2nd Annual American Society for Bioethics and Humanities, October 28-31, 1999.

28. Morris A, Silverman H, Shanholtz C, Brower R, Thompson T, Bernard G. Experimental Design and Ethical Issues for Non-Blinded ICU Randomized Controlled Clinical Trials. ATS 2003. Seattle. 99th International Conference.

MAJOR INVITED LECTURES - Basic Science

9/83 Adult Respiratory Distress Syndrome, Grand Rounds; Hartford Memorial Hospital, Havre de Grace, Maryland

10/83 Clinical-Pathological Conference, Mercy Hospital, Baltimore, Maryland.

11/84 Chronic Obstructive Pulmonary Disease, Grand Rounds; Hartford Memorial Hospital, Havre de Grace, Maryland.

12/84 Chronic Obstructive Pulmonary Disease, Howard County Hospital, Columbia, Maryland.

1/85 Asthma, Grand Rounds, Doctor's Hospital of Prince Georges County, Maryland.

1/85 Controversies in the Pulmonary Therapy for Acute Atelectasis and Pneumonia, Baltimore Critical Care Medicine Society, Baltimore, Maryland.

2/85 Laser Bronchoscopy, Pulmonary Grand Rounds, Johns Hopkins Hospital; Baltimore, Maryland.

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3/85 Mixed Venous Determinations in Critically Ill Patients, Nursing Grand Rounds, University of Maryland, Baltimore, Maryland.

5/85 Efficacy and Safety of Naloxone in Septic Shock, Journal Club at Greater Baltimore Medical Center; Baltimore, MD.

2/86 Treatment of Asthma in the ICU Setting, Medical Grand Rounds, Maryland General Hospital, Baltimore, Maryland.

4/86 YAG Laser to the Tracheobronchial Tree, Program of Continuing Education, University of Maryland, Baltimore, Maryland.

4/86 Pneumonia in the ICU, Grand Rounds, Washington County Hospital, Washington, D.C.

4/86 YAG Laser to the Tracheobronchial Tree, University of Maryland YAG Laser Course, Baltimore, Maryland.

4/88 Emergency Room Management of Asthma - Current Concepts, Dean's Conference, University of Maryland, Baltimore, MD.

6/88 Acute Respiratory Failure, Community College of Baltimore, Baltimore, Maryland.

6/88 Pulmonary Artery Catheterization, Washington Hospital Center, Grand Rounds, Washington, D.C.

11/88 Workshop: Problems in Pulmonary Disease. Medical Perioperative Management Course, University of Maryland, Baltimore, Maryland.

4/89 Emergency Room Treatment of Asthma. Union Hospital of Cecil County, Maryland.

8/89 Prostaglandin E1 in the Adult Respiratory Distress Syndrome. Shinshu University, Matsumoto, Japan.

3/90 Could Prostaglandins Prevent ARDS and MOF? International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium.

3/90 Myocardial Dysfunction. International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium.

3/90 ARDS in the 1990's. Critical Care Conference Guys Hospital, London, England.

10/90 Desensitization of Beta-Receptors in Sepsis. Critical Care Conference, Erasme Hospital, Brussels, Belgium.

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11/90 Oxygen Transport in Sepsis. Grand Rounds, Georgetown University, Washington, D.C.

12/90 Septic Shock in the ICU. Grand Rounds, Maryland General Hospital, Baltimore, Maryland.

1/91 Desensitization of beta-receptors. Walter Reed Hospital, Bethesda, Maryland

1/91 Improving Survival in Septic Shock. Grand Rounds, Howard University, Washington, D.C.

3/91 Treatment of Septic Shock. Conference - New Trends in Critical Care - Danville Memorial Hospital, Danville, Virginia

4/91 Septic Shock - New Trends. Grand Rounds, Newport News General Hospital, Newport News, Virginia

5/91 Treatment of Septic Shock. Grand Rounds, Prince Georges Hospital, Prince Georges, Maryland

10/91 Oxygen Transport in Sepsis. Grand Rounds, Washington Hospital Center, Washington D.C.

11/91 Oxygen Delivery and Oxygen Consumption in Septic Patients. Grand Rounds: The Chinese University of Hong Kong, Hong Kong.

11/92 Critical Care for the Cardiologist. American Heart Association, 1992 Annual Meeting, New Orleans, Louisiana

11/92 Gastric Tonometry in the ICU. Pulmonary/Critical Care Division, LSU, New Orleans, Louisiana.

12/92 Treatment of Sepsis and Septic Shock. Southern Maryland Hospital, Clinton, Maryland

3/93 Gastric Tonometry in Critical Ill Patients. Pulmonary/Critical Care Division, St. Johns Mercy Medical Center, St. Louis, Missouri.

5/93 Oxygen Delivery in Septic Patients. Grands Rounds, New England Medical Center, Boston, Massachusetts.

11/93 Myocardial Depression in Sepsis. Walter Reed Hospital, Bethesda, Maryland.11/93 Regional Oxygenation. A Symposium on ICU Monitoring Techniques. American

College of Chest Physicians, 1993 Annual Meeting, Orlando, Florida.5/94 Gastric Tonometry. Visiting Professor, Winthrop-University Hospital Mineola, Long

Island, New York

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5/95 Sepsis and ARDS. Fifth Vienna Shock Forum May 7-11, 1995, Ludwig-Boltzman Institute for Experimental and Clinical Traumatology

MAJOR INVITED LECTURES - Ethics

2/89 Ethical Issues in Critical Care. Faith Presbyterian Church, Baltimore, Maryland.

4/89 Taking Treatment Away: Legal and Ethical Perspectives. President's Colloquium, University of Maryland.

5/89 Ethics in Medicine. AMA Regional Conference. Uniform Services Medical School, Bethesda, Maryland.

8/89 Pulling the Plug. Phlebotomy Society. Baltimore, Maryland.

3/90 Who Decides Who Shall Live, Who Shall Die. Maryland Society of Social Work Directors, Baltimore, Maryland.

3/90 Hospital Standards as Related to Terminal Illnesses. Hemlock Society of Maryland, Baltimore, Maryland

3/92 Survey of the attitudes and beliefs of a hospital staff concerning medical ethical decisionmaking. University of Maryland Bioethics Group.

3/92 Medical Decisionmaking. Panel Discussion; Health Law Section of the Maryland Bar Association; Baltimore, Maryland.

3/93 Hospital Ethics Committees. Grand Rounds. Miners Memorial MedicalCenter, Coaldale, Pennsylvania.

4/93 Starting An Ethics Committee. Garrett Memorial Hospital, Garrett County, Maryland.

9/93 Implementing the Maryland Health Care Decisions Act. The Law and Health Care Program of the University of Maryland School of Law.

10/93 Advance Directives. Grand Rounds. York Hospital, York, Pennsylvania.

11/93 Decisionmaking for Incompetent Patients. Grand Rounds. Mercy Hospital. Baltimore, Maryland.

1/94 Health Care Reform and Rationing. Lecture Series: Beth Tefiloh Synagogue

4/94 Decisionmaking from an Ethical Viewpoint. Sinai Hospital Symposium: Decision making from a Pastoral and Ethical Viewpoint. Baltimore, Maryland.

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4/94 An Initial Evaluation of the PSDA Program in Bioethics: College of Medicine, Iowa University, Iowa

5/94 Health Care Decisions Act: New Rights and Responsibilities. 196th Annual Meeting of the Medical and Chirurgical Faculty of Maryland. Hagerstown, Maryland

5/94 Ethical Dimensions of Medical Decision-Making. 11th Annual Therapeutic Update, Upper Chesapeake Health Group.

5/94 Implementation of the Patient Self-Determination Act, Visiting Professor, Winthrop-University Hospital Mineola, Long Island, New York

10/94 Maryland Health Care Decisions Act. Anne Arundel General Hospital, Annapolis, Maryland

10/94 Effects of the Patient Self-Determination Act. Symposium on the PSDA, Washington Hospital Center Washington, D.C.

1/95 Ethics in Health Care: Theory and Practice. VAMC, Washington, D.C.

2/95 Last Weeks of Life - How Much is Enough? Grand Rounds, Pennsylvania Hospital, Pennsylvania

6/95 Should Rationing Be Based on Age? Grand Rounds, Bon Secours Hospital, Baltimore, Maryland.

10/95 The Ethics of Age-Based Rationing. Laurel General Hospital, Laurel, MD

2/96 Is Age-Based Rationing in the ICU Appropriate? Society of Critical Care Medicine. Annual Meeting. New Orleans, LA. Feb 5-9, 1996.

4/96 The Last Weeks of Life: How Much is Enough? Special Topics in Critical Care. UMMS. April 23, 1996.

5/96 How I See this Case: I’m not ready to lose her yet. Ethics Consultation 1996: The State of the Art. Society of Bioethics Consultation. West Virginia University. May 17, 1996.

10/96 Withholding or Withdrawal of Life-Sustaining Therapy. American College of Chest Physicians. World Meeting. San Francisco. October, 1996.

11/96 The Unbearable Rightness of Rationing. A Debate on Cardiovascular Care in the United States. Managed Care, Ethical Issues and Health Care Reform. Chief Medical Residents’ Conference. Tucson, Arizona

2/97 Patient’s Rights and Organizational Ethics: Joint Commission Standards and Emerging Responsibilities. The Baltimore Area Ethics Network. Feb. 20, 1997.

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2/97 Pros and Cons of Physician-Assisted Suicide, Moderator. AMA-MSS Sectional Conference. University of Maryland School of Medicine. Baltimore, Maryland. February 22, 1997.

2/97 The Ethics of Age-Based Rationing, Grand Rounds Franklin Square Hospital, Baltimore, MD

5/97 Physician Assisted Suicide or an Alternative Method. Panel Discussion. St. Joseph Medical Center. Baltimore, MD

3/98 Ethics Committees and Models of Consultation. Contemporary Challenges & Controversies For Nurses: The Interface of Ethics, Law and Policy. Baltimore, MD

3/98 What’s New in End-of-Life Decision Making? Keynote Speaker. Ethics Conference. Charles County Community College. La Plata, Maryland.

4/98 Clinical Year in Review: Ethics in Pulmonary and Critical Care. 1998 American Thoracic Society/American Lung Association International Conference. Chicago, Ill.

1/99 Ethics in Critical Care: Year in Review. 1999 Society of Critical Care Medicine Annual Conference. San Francisco.

3/00 Discussions with Seriously Ill Patients: What are the guiding principles, the barriers, and practical approaches. Visiting Professor. Cleveland Clinic

4/00 Ethical, Legal, and Social Implications of Genetic Testing. Panel Discussion. Alpha-1 Association’s Education Conference. Charlotte, N.C.

4/01 Ethics & Clinical Trials: What are the Current Concerns? Clinical Trials Management Workshop. Sponsored by Trial Builder and University of Maryland School of NursingBaltimore, MD

6/01 Targeting Appropriate Populations for Alpha-1 Genetic Testing. Conference on Alpha-1: The Challenge of a Genetic Condition. Airlie Center, Virginia

10/01 Sponsor Responsibilities In Developing Countries After A Study Concludes. Janssen International Research Ethics Program. Titusville, N.J.

3/02: Visiting Professor: North Shore University Hospital: Protecting Human Subjects in Research

5/02 Protecting Human Subjects in Critical Care Clinical Research. Presented at a Symposium entitled “Building the Critical Care Clinical Research Laboratory”. American Thoracic Society International Meeting. Atlanta, Ga.

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10/04 State Laws in the USA. Presented at: Experts Conference on Ethics in Research. European Society Of Intensive Care Medicine. Amsterdam, The Netherlands, October 4-8, 2003.

11/03 Protecting Decisionally Impaired Subjects in Research: the Need for a Multifaceted Approach. Presented at: The Ethical Conduct of Clinical Research Involving Critically Ill Subjects in North American. Washington, DC, November 21-22, 2003

3/04 Egypt Conference on Ethical Aspects of Clinical Research In Developing Countries. “Case on Risks and Benefits” Cairo, Egypt. March 16-18, 2004.

3/04 Visiting Professor. The University of North Carolina at Chapel Hill. “Protecting Human Subjects in Research”

12/04 Advance course in Research Ethics. Zanzibar: December 1-3, 2004“Case on Informed Consent” Zanzibar: December 1-3, 2004

11/06 “United States Malpractice Litigation: “Wrong Solution to a Just Cause?” presented at the Journée d'Ethique Médicale Maurice RAPIN Conference: “Is the Patient the All Powerful?” Paris, France. November 18, 2006.

8/2008 “First Meeting of the Eastern Mediterranean and Arab Region in Research Ethics”“Research Ethics in the EMRO Region”, Cairo, Egypt. August 8, 2008

1/2011 Visiting Professor. Jizan University, Saudi Arabia.“Medical Ethics. January 22, 2011.

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