Page 1
Page 1 of 5SWGDRUG.org/monographs.htmLatest Revision: 5/12/2017
6-Methoxy MethyloneThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
1. GENERAL INFORMATION
IUPAC Name: 1-(6-methoxy-2H-1,3-benzodioxol-5-yl)-2-(methylamino)propan-1-one
CAS#: Not Available
Synonyms: Not Available
Source: DEA Reference Material Collection
Appearance: Tan powder
UVmax(nm): Not Determined
2. CHEMICAL AND PHYSICAL DATA
2.1 CHEMICAL DATA
Form Chemical Formula Molecular Weight Melting Point (oC)
Base C12H15NO4 237.25 Not Determined
HCl C12H15NO4 HCl 273.71 Not Determined
152.2
O
O
O
O
CH3
CH3
NHCH3
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Page 2 of 5SWGDRUG.org/monographs.htmLatest Revision: 5/12/2017
6-Methoxy MethyloneThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
3. QUALITATIVE DATA
3.1 NUCLEAR MAGNETIC RESONANCE
Sample Preparation: Dilute analyte to ~5 mg/mL in D2O containing TMS for 0 ppm reference and dimethylsulfone as quantitative internal standard.
Instrument: 400 MHz NMR spectrometerParameters: Spectral width: at least containing -3 ppm through 13 ppm
Pulse angle: 90o
Delay between pulses: 45 seconds1HNMR: 6-Methoxy Methylone HCl; Lot# 0472654-6; D2O; 400MHz
7 6 5 4 3 2 1 0
0
1
2
3
4
5
6
7
8
9
10
3331211
Dimethylsulfone
TSP
HDO
7.375
1
6.875
1
6.100
2
4.000 3.950
3
5.000
1
1.575
3
2.800 2.750
3
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Page 3 of 5SWGDRUG.org/monographs.htmLatest Revision: 5/12/2017
6-Methoxy MethyloneThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
3.2 GAS CHROMATOGRAPHY/MASS SPECTROMETRY
Sample Preparation: Dilute analyte ~3 mg/mL in CHCl3 base extracted with NaOH.
Instrument: Agilent gas chromatograph operated in split mode with MS detectorColumn: DB-5 MS (or equivalent); 15m x 0.25 mm x 0.25mCarrier Gas: Helium at 1.5 mL/minTemperatures: Injector: 280oC
MSD transfer line: 280oCMS Source: 250oCMS Quad: 150oCOven program:
1) 100oC initial temperature for 1.0 min2) Ramp to 280oC at 12 oC/min3) Hold final temperature for 9.0 min
Injection Parameters:MS Parameters:
Retention Time:
Split Ratio = 25:1, 1 L injected Mass scan range: 30-550 amu Threshold: 150Tune file: stune.uAcquisition mode: scan8.54 min
EI Mass Spectrum: 6-Methoxy Methylone HCl; Lot# 0472654-6
m/z240220200180160140120100806040
[x 1
06 ]In
tens
ity
1
2
3
4
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
208
208
208
208
208
208
208
208
208
208
208
208
208
208
208
208
208
208
208
208
208
208
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
19017
917
917
917
917
917
917
917
917
917
917
917
917
917
917
917
917
917
917
917
917
917
9
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
939393 9393939393 9393939393 9393939393 93939393787878 7878787878 7878787878 7878787878 78787878
656565 6565656565 6565656565 6565656565 65656565585858 5858585858 5858585858 5858585858 58585858
424242 4242424242 4242424242 4242424242 42424242EI+
[x 1
04 ]In
tens
ity 237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
237
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
222
22220
820
820
820
820
820
820
820
820
820
820
820
820
820
820
820
820
820
820
820
820
820
8
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
190
179
179
179
179
179
179
179
179
179
179
179
179
179
179
179
179
179
179
179
179
179
179
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
164
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
152
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
137
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
121
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107
107939393 9393939393 9393939393 9393939393 93939393787878 7878787878 7878787878 7878787878 78787878656565 6565656565 6565656565 6565656565 65656565585858 5858585858 5858585858 5858585858 58585858424242 4242424242 4242424242 4242424242 42424242
EI+
Page 4
1700 1600 1500 1400 1300 1200 1100 1000 900 800 700 Wavenumber (cm-1) Latest Revision: 5/12/2017 SWGDRUG.org/monographs.htm Page 4 of 5
6-Methoxy MethyloneThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
3.3 INFRARED SPECTROSCOPY (FTIR)
Insrument: FTIR with diamond ATR attachment (1 bounce)Scan Parameters: Number of scans: 32
Number of background scans: 32Resolution: 4 cm-1
Sample gain: 1Aperture: 150
FTIR ATR (Diamond 1 Bounce): 6-Methoxy Methylone HCl; Lot# 0472654-6
Wavenumber (cm-1)3500 3000 2500 2000 1500
%Tr
ansm
ittan
ce
48
56
64
72
29692969296929692969296929692969296929692969296929692969296929692969296929692969296929692909290929092909290929092909290929092909290929092909290929092909290929092909290929092909
27532753275327532753275327532753275327532753275327532753275327532753275327532753275327532716271627162716271627162716271627162716271627162716271627162716271627162716271627162716 1651
165116511651165116511651165116511651165116511651165116511651165116511651165116511651
1619161916191619161916191619161916191619161916191619161916191619161916191619161916191619
1505150515051505150515051505150515051505150515051505150515051505150515051505150515051505 1483
148314831483148314831483148314831483148314831483148314831483148314831483148314831483 1423
142314231423142314231423142314231423142314231423142314231423142314231423142314231423
1373137313731373137313731373137313731373137313731373137313731373137313731373137313731373
12631263126312631263126312631263126312631263126312631263126312631263126312631263126312631235123512351235123512351235123512351235123512351235123512351235123512351235123512351235
1200120012001200120012001200120012001200120012001200120012001200120012001200120012001200
1119111911191119111911191119111911191119111911191119111911191119111911191119111911191119
1034103410341034103410341034103410341034103410341034103410341034103410341034103410341034
1009100910091009100910091009100910091009100910091009100910091009100910091009100910091009
917917917917917917917917917917917917917917917917917917917917917917 897
897897897897897897897897897897897897897897897897897897897897897
827827827827827827827827827827827827827827827827827827827827827827
771771771771771771771771771771771771771771771771771771771771771771
738738738738738738738738738738738738738738738738738738738738738738
644644644644644644644644644644644644644644644644644644644644644644
615615615615615615615615615615615615615615615615615615615615615615
479479479479479479479479479479479479479479479479479479479479479479
%Tr
ansm
ittan
ce
48
56
64
72
1651165116511651165116511651165116511651165116511651165116511651165116511651165116511651
1619161916191619161916191619161916191619161916191619161916191619161916191619161916191619
1505150515051505150515051505150515051505150515051505150515051505150515051505150515051505 1483
148314831483148314831483148314831483148314831483148314831483148314831483148314831483 1423
142314231423142314231423142314231423142314231423142314231423142314231423142314231423
1373137313731373137313731373137313731373137313731373137313731373137313731373137313731373
12631263126312631263126312631263126312631263126312631263126312631263126312631263126312631235123512351235123512351235123512351235123512351235123512351235123512351235123512351235
1200120012001200120012001200120012001200120012001200120012001200120012001200120012001200
1169116911691169116911691169116911691169116911691169116911691169116911691169116911691169
1119111911191119111911191119111911191119111911191119111911191119111911191119111911191119
1084108410841084108410841084108410841084108410841084108410841084108410841084108410841084
1034103410341034103410341034103410341034103410341034103410341034103410341034103410341034
1009100910091009100910091009100910091009100910091009100910091009100910091009100910091009
917917917917917917917917917917917917917917917917917917917917917917 897
897897897897897897897897897897897897897897897897897897897897897
847847847847847847847847847847847847847847847847847847847847847847 827
827827827827827827827827827827827827827827827827827827827827827
771771771771771771771771771771771771771771771771771771771771771771
738738738738738738738738738738738738738738738738738738738738738738
644644644644644644644644644644644644644644644644644644644644644644
615615615615615615615615615615615615615615615615615615615615615615
479479479479479479479479479479479479479479479479479479479479479479
446446446446446446446446446446446446446446446446446446446446446446
Page 5
Page 5 of 5SWGDRUG.org/monographs.htmLatest Revision: 5/12/2017
6-Methoxy MethyloneThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
http://forendex.southernforensic.org/index.php/detail/index/1012
4. ADDITIONAL RESOURCES
No Literature Available as of 12/2016
