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6 the Respiratory System

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    Anatomy of the Larynx

    Thyrohyoidmembrane

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    Cartilages of the Larynx

    Hyaline cartilage:

    1 thyroid cartilage 1cricoid cartilage

    2 arytenoid cartilage

    Fibroelastic cartilage:- the epiglottis

    Thyrohyoidmembrane

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    The Thyroid Cartilage

    Laminae are separated, v-shape notch known as thyroidnotch

    Upper part lined with

    stratified squamous epithelium,

    lower part with

    ciliated columnar epitheliumThyrohyoidmembrane

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    The Cricoid Cartilage

    This lies below thyroid cartilage

    Shaped like ring, circling the larynx with a narrow partanteriorly, broad part posteriorly

    Broad part articulates with

    arytenoid cartilages,

    inferior cornu of

    thyroid cartilage

    lined with ciliatedcolumnar epithelium

    Thyrohyoidmembrane

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    The arytenoid cartilages:

    Two roughly pyramid shaped

    situated on top of broad part of cricoid cartilage

    give attachment to vocal cords & muscles

    lined with ciliated columnar epithelium

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    The Epiglottis

    Leaf shaped fibroelastic cartilage

    Attached to the inner surface of the anterior wall of

    thyroid cartilage, below thyroid notch

    Covered with stratified squamos epithelium

    Larynx is likened to a box and

    epiglottis as a lid

    So it closes of larynx during

    swallowing & protect the lungs

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    Interior of the larynx:

    Vocal cords are two pale folds of mucousmembrane from the inner side of thyroid cartilage

    anteriorly to the arytenoid cartilages posteriorly.

    Muscles controlling the vocal cords are

    Relaxed Contracted

    Vocal cords open

    (Abducted)

    Vocal cords stretched out

    (Adducted)

    Pitch of the sound is low Pitch of the sound is high

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    The Glottis

    Vocal cord

    abducted

    Vocal cord

    adducted

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    Functions:

    Production of sound:

    1. Voice depends upon the length and tightness of vocal cord

    2. Volume of the voice depends upon the force with which cords

    vibrate

    greater the force of expired air

    more cords vibrate and the louder sound emitted3. Tone is depending upon the shape of the mouth, position

    of tongue, lips, facial muscles and air in Para nasal sinuses

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    Speech: This occurs during expiration when the sounds

    produced by the vocal cords are manipulated by the

    tongue, cheeks and lips

    Protection of the lower respiratory tract: During

    swallowing, larynx moves upwards, and epiglottis closes

    over the larynx.

    Passageway of air: between pharynx and trachea

    Humidifying, filtering and warming

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    What is the structure ofairways outside the lungs?

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    Gross Anatomy of the Lungs

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    The Lungs Two lungs, cone shaped having an

    apex, base, costal surface & medialsurface

    The Apex : rounded, rises into the rootof the neck, about 25 mm (1 inch)above the clavicle

    structures associated: first rib, blood

    vessels & nerves in root of the neck

    The Base: concave in shape.

    closely associated with the thoracic

    (superior) surface of the diaphragm

    Position and associated structures:

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    The Costal surface: Surface is convex.

    closely associated with cartilages, the ribs and

    the intercostals muscles

    The Medial surface: Surface is concave & has

    roughly triangular shaped area called hilum atthe level of 5th, 6th & 7th thoracic vertebrae

    Structures which form root of the lung enter &

    leave at the hilum, include

    primary bronchus,

    -pulmonary artery supplying

    the lung & two pulmonary veins draining it,

    - bronchial artery & veins, and

    -the lymphatic and

    -nerve supply

    Area betn the lungs is the mediastinum occupied by the heart, great vessel, trachea,

    right and left bronchi, oesophagus, lymph nodes, lymph vessels and nerves

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    The Right Lung:

    Has 3 lobes: superior, middle, and inferior

    separated by horizontal and oblique fissures

    Organization of the Lungs:

    The Left Lung: It is smaller as the heart is situated left of the midline

    Has 2 lobes:

    superior and inferior

    are separated by an oblique fissure

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    Pleura and Pleural Cavity:

    Pleura consists of a closed sac of serous membrane which contain

    small amount of serous fluid

    Lung is invaginated into this sac so that it forms two layers:

    One adheres to the lung and other to the wall of thoracic cage

    The Visceral Pleura: adherent to the lung

    The Parietal Pleura: adherent to the inside of the chest wall &

    the thoracic surface of the diaphragm

    The Pleural cavity: Two layers of pleura are separated by only

    a thin film of serous fluid,

    1.which allows them to glide over each other

    2. prevent friction between them during breathing

    Serous fluid is secreted by the epithelial cells of the serous membrane

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    Interior of the Lung:

    composed of the bronchi and smaller air passages, alveoli, connective

    tissue, blood vessels, lymph vessels, nerves.

    Pulmonary blood supply: pulmonary artery divides into two, one

    branch conveying deoxygenated blood to each lung

    Within the lungs,

    Walls of the alveoli and capillaries each consist of only one layer offlattened epithelial cells

    Exchange of gases between air in the alveoli and blood in the

    capillaries takes place across this two very fine membranes

    The Pulmonary capillaries join up and become two pulmonary veins

    in each lung,

    Which leave the lungs at hilum and convey oxygenated blood to the

    left atrium of the heart

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    Relationship between Lungs and Heart

    Figure 238

    i i

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    Refers to 2 integrated processes:

    external respiration

    internal respiration

    External Respiration

    Includes all processes involved in exchanging O2 and CO2 with

    the environment

    Internal Respiration

    Also called cellular respiration

    Involves the uptake of O2 and production of CO2 within individual

    cells

    Respiration

    Inflation and deflation of the lungs with each breath ensures that

    regular exchange of gases

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    Muscles of respiration:

    In normal breathing,

    Intercostal muscles and diaphragm

    During difficult or deep breathing,

    They are assisted by the muscles of neck, shoulders and abdomen

    Intercostal muscles:11 pairs of muscles that occupy the spaces between the 12 pairs of ribs

    Arranged in two layers,External And Internal Intercostal Muscle

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    The first rib is fixed, therefore, when intercostal muscles contract

    they pull all the ribs towards first rib

    Bcoz of the shape they move outward, when pulled upward

    In this way thoracic cavity enlarged anteriorly, posteriorly and

    laterally

    Intercostal muscles are stimulated to contract by intercostal nerves

    Diaphragm

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    Diaphragm

    Dome shaped structure separating the thoracic and abdominal cavities

    forms the floor of the thoracic cavity and roof of the abdominal cavity

    It consist of central tendon from which muscle fibres radiate to be attached tothe lower ribs and sternum

    It is supplied by the Phrenic nerves

    When the muscle of diaphragm,

    Relaxed Contracts

    central tendon is at the level

    8th thoracic vertebra 9th thoracic vertebra

    (muscle fibre shortens, central

    tendon pulled downwards)

    Enlar in the thoracic cavit

    decreases pressure in the thoracic cavity

    and increases it in the abdominal and

    pelvic cavities

    Intercostal muscles & diaphragm

    contract simultaneously ensure

    enlargement from all side

    Cycle of respiration:

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    Cycle of respiration:

    This occur 12 to 15 times per minute and consists of three phases:

    Inspiration Expiration Pause

    I i i i f h i i i d

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    Inspiration: capacity of thoracic cavity increased

    by simultaneous contraction of both muscles

    Parietal pleura moves with the walls of thoraxand the diaphragm

    Reduces pressure in the pleural cavity than atmospheric pressure

    Visceral pleura follows parietal pleura &

    pulling lung with it

    Stretches the lungs & the pressure within alveoli fall down

    in order to equalize atm. & alveolar pressure

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    Expiration: Relaxation of the both muscles results in

    Downward and inward movement of rib cage &

    elastic recoil of lungs

    Pressure inside the lungs exceeds that in the

    atmosphere

    And therefore air is expelled

    Inspiration Expiration

    active process passive process

    Requires expenditure of energy not require

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    Blood flow

    to alveolus

    Blood flow

    from alveolus

    PO2 100 mm Hg

    PCO2 40 mmHg

    Atmospheric Air

    PO2 40 mm Hg

    PCO2 44 mmHg

    PO2 100 mm Hg

    PCO2 40 mmHg

    Blood Capillary

    Pulmonary

    Artery

    Pulmonary

    Vein

    Fig. External Respiration : Exchange of gases between alveolar air

    and capillary blood

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    CO2

    O2

    Diffusion of Co2

    Blood Flow

    Diffusion of O2

    Cells

    Tissue fluid

    Venous end of

    capillary

    Fig. Internal respiration : exchange of gases betn capillary and tissues

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    Transport of gases in the blood stream:

    Transport of blood oxygen and Carbon dioxide necessary for

    internal respiration

    Oxygen: present with heamoglobin 98.5%

    present in plasma water 1.5 %

    Dissociates from these

    Factors of dissociation: increased CO2 level in tissue fluid,

    raised temp., 2,3- diphosphoglycerate present in RBC

    In active tissues increased production of CO2 and heat

    leads to increase release of oxygen

    Carbon dioxide: waste product of metabollism

    1. In the form of bicarbonate ions in the plasma 70 %

    2. In the plasma 7%, 23 % heamoglobin

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    Control of respiration

    The respiratory center

    Chemoreceptors

    Peripheral receptors

    Heiring-Breur reflex

    Other factors: singing, speeking,

    laughing, crying, sneezing and other

    environmental factors


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