69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013

Photographs courtesy of the Greater Boston Convention & Visitors Bureau

First Preliminary ProgramTransforming Reproductive Medicine Worldwide

OCTOBER 12 - 17, 2013

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Boston is more vibrant than ever! New green spaces are sprouting up all over, and a revitalized waterfront has added to the city’s already dynamic downtown neighborhoods. These developments are thanks in part to the city’s Big Dig project, which is now complete. Additionally, Logan International Airport’s recent upgrades are making it easier than ever to get in and out of the city, and new sights and attractions are providing more for everyone to see and do while in Boston.

Boston’s Waterfront has become an idyllic setting for watching sailboats and ferries glide in and out of the harbor and an excellent destination for classic New England seafood restaurants.

Boston’s Rose Kennedy Greenway consists of three parks and a total of 30 acres of beautiful, tree-lined corridors. Visitors will find more than 900 trees, public art, fountains and great places for exercise or contemplation. In the works for the Greenway are the Boston Museum Project, which will focus on the last 200 years of Boston history, and The New Center for Arts and Culture, which will present a variety of dance performances, films, music, lectures and art.

The new 44-mile Boston HarborWalk includes the downtown Boston waterfront and continues north and south along wharves, piers, museums, historic forts, bridges, beaches and shoreline from Chelsea Creek to the Neponset River. The HarborWalk also connects to new and existing trails: The Freedom Trail, the new Walk To The Sea, the Emerald Necklace, the Charles River Esplanade, the Rose Kennedy Greenway, and in the future, the South Bay Harbor Trail.

The one-mile Walk To The Sea is a Beacon Hill-to-the-waterfront marked walkway. Beginning at the Massachusetts State House, the visitor learns about the four centuries of maritime history from Beacon Hill to State Street to the 18th century Long Wharf.

Constructed from dirt excavated from the Big Dig’s extensive network of tunnels, Spectacle Island in Boston Harbor features a marina, visitor center, sandy beaches and five miles of walking trails that lead to the crest of a 157-foot hill offering panoramic views of the harbor and the city. Visitors are welcome from dawn to dusk during the summer months. Passenger ferry service is available from Boston.

Chinatown Park, a beautiful parcel of land in Chinatown, is populated by bamboo trees, azaleas, stones and a peaceful stream. The new park is situated at the south end of the Greenway and is the perfect place to experience the Chinese ideal of Feng Shui, followed by an authentic dim sum meal.

History around every corner, and so much more! Boston’s rich art, music and dance institutions, theatre and cultural attractions, distinguished dining and nightlife venues, world-class shopping and championship sports teams make it a unique place for travelers to visit. The city’s downtown neighborhoods offer endless unique experiences and its proximity to other must-see sites all around New England make it one of the country’s most diverse and exciting locales.

Here in Boston, visitors are never at a loss for things to do. The many museums, concert halls, theaters and nightclubs are always showcasing great talent and events. There’s the internationally acclaimed Museum of Fine Arts, the Museum of Science, New England Aquarium and the John F. Kennedy Presidential Library & Museum. Beyond the museum scene, there’s the world-famous Boston Symphony Orchestra and Boston Pops, local and pre-Broadway theater, distinctive dining, endless opportunities for shopping and sightseeing, and a year-round calendar of special events and celebrations.

Boston is home to a grand tradition of sporting excellence. This is where storied franchises such as the Red Sox (2004 and 2007 World Series Champions), the Celtics (2008 World Champions), the Bruins, and the New England Patriots (2001, 2003 and 2004 Super Bowl champions) all play their games. Visiting sports fans can’t help getting caught up in the enthusiasm.

In addition to everything within the city limits, some of Massachusetts’ most scenic and historic towns are just a short distance from the city center. There are sights to see at every turn. Cambridge is often referred to as “Boston’s Left Bank” with an atmosphere — and attitude — all its own. It’s the spirited, slightly mischievous side of Boston, just a bridge away on the other side of the Charles River. Packed with youthful vitality and international flair, it’s a city where Old World meets New Age in a mesmerizing blend of history and technology. As the East Coast’s leading hub for high tech and biotech, Cambridge has a creative, entrepreneurial spirit. It is also the birthplace of higher education in America. Harvard College was founded in 1636, and across town, Massachusetts Institute of Technology (MIT) is known as the epicenter of cyberculture. Both universities house renowned museum collections and tours that are open to the public. As a captivating, offbeat alternative to Boston’s urban center, the “squares” of Cambridge are charming neighborhoods rich in eclectic shopping, theaters, museums and historic sites. Cambridge also offers a tantalizing array of dining options for the visitor with a sophisticated palate.

Welcome to Boston!

Information on Boston provided by the Greater Boston Convention and Visitors Bureau

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NIGHT MUSEUMATTHE

OF SCIENCEBOSTON • MA

MIX, MINGLE& BE BLINDEDBY SCIENCE!

Wednesday, October 16, 20137:00 pm - 9:00 pm

Tickets $125

Explore Boston's Museum of Science Heavy hors d'oeuvres • Beer • Wine

Transportation will be provided.

Exciting events coming your way in 2013!

Make plans now to participate in the

4th annual ASRM 5k Run &1 mile Walk

Monday • October 14, 2013Boston, MA

Get a step ahead!

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IFFS/ASRM WELCOME

WELCOME TO BOSTON . . . . . . . . . . . 2

MUSEUM NIGHT . . . . . . . . . . . . . . . . 3

OPENING CEREMONY & NETWORKING EVENT . . . . . . . . . . . . . . 4

ASRM 5K RUN INFORMATION . . . . . . 4

IFFS/ASRM WELCOME . . . . . . . . . . . . 5

IFFS/ASRM CONJOINT MEETING PROGRAM PLANNING COMMITTEE . . . . . . . . . . . 6

IFFS OFFICERS ANDBOARD OF DIRECTORS . . . . . . . . . . . 7

ASRM OFFICERS ANDBOARD OF DIRECTORS . . . . . . . . . . . 7

IFFS/ASRM ANNUAL MEETINGPOLICIES & DISCLAIMERS . . . . . . . . . 8

REGISTRATION & MEETINGINFORMATION . . . . . . . . . . . . . . . . 9-11

HOUSING INFORMATION . . . . . . 12-13

DISCLOSURE STATEMENTS &CONFLICT OF INTEREST POLICY . . .14

POSTGRADUATE PROGRAM . . . . . . . . . . . . . . . . . . 15-30

FUTURE ASRM MEETING DATES . . . 30

NEEDS ASSESSMENT &LEARNING OBJECTIVES . . . . . . . . . 31

IFFS/ASRM 2013CONJOINT MEETING GRID . . . . . . . 32

SCIENTIFIC PROGRAMDAILY SCHEDULE . . . . . . . . . . . . . 33-38

MENOPAUSE DAY . . . . . . . . . . . . . . . 39

SURGERY DAY . . . . . . . . . . . . . . . . . . 40

CONTRACEPTION DAY . . . . . . . . . . . 41

SPOUSE/GUEST PROGRAM . . . . . . . 41

PLENARY SESSIONS . . . . . . . . . . 42-43

TRILOGIES . . . . . . . . . . . . . . . . . . . 44-49

ASRM MORNING SYMPOSIA . . . . . . . 50

ASRM AFTERNOONSYMPOSIA . . . . . . . . . . . . . . . . . . 51-52

INTERACTIVE SESSIONS . . . . . . 53-56

SMRU MINI-SYMPOSIA . . . . . . . . . . . 56

VIDEO SESSIONS . . . . . . . . . . . . . . . 56

WRITE THE NEXT CHAPTER CONTRIBUTION OPPORTUNITIES . . 59

INSIDEDear Colleagues, I write as President of the International Federation of Fertility Societies (IFFS) to invite you to our 21st World Congress to be held conjointly with the American Society for Reproductive Medicine (ASRM), one of our very senior member societies, in Boston on October 12-17, 2013. It is a pleasure for IFFS to thank Dr. Linda Giudice and the ASRM staff for their co-operation and help to IFFS over the past three years. Building on the strong foundation of the 2010 IFFS World Congress in Munich, our last Triennial Congress, features such as regional sessions and live surgery have been incorporated into the 2013 program. The Regional Sessions are planned and presented by IFFS member societies, most often in the language of their country. For those who are unfamiliar with IFFS, the Federation was

founded in 1951 with an educational mission. Each year IFFS conducts workshops in selected cities in underdeveloped countries, sponsors a Symposium in its International Series on topics of regional concern, and every three years holds a World Congress. Today more than 70 national societies from around the globe are members of the Federation. Our 2013 Program Chair, Dr. Basil Tarlatzis, and his colleagues, have crafted an exciting program for Boston using the trilogy structure, the hallmark of past IFFS World Congresses. So mark October 12 -17, 2013, in all your diaries and electronic devices now - you will never, never know how good Boston is if you never, never go!

Sincerely,

Dr. David Healy, FRANZCOG, FRCOG, Ph.D. IFFS President 2010 -2013

David Healy, M.D., Ph.D.IFFS President 2010-2013

As President-elect of the American Society for Reproductive Medicine (President 2012-2013), I enthusiastically welcome you to the 69th Annual Meeting of the ASRM conjoint with the 21st Meeting of the International Federation of Fertility Societies (IFFS) in Boston, Massachusetts, October 12-17, 2013. Serdar Bulun and the ASRM Scientific Program Committee along with Basil Tarlatzis and the IFFS Scientific Committee have put together a phenomenal program, along with Anuja Dokras for the Postgraduate Program and Steven Palter for the Video Program. As a conjoint meeting, we have extended the program by one day to accommodate additional interactive poster sessions, the traditional IFFS trilogies, and regional meetings for our international societies. The theme of our conjoint meeting is “Transforming Reproductive Medicine Worldwide,” and we have planned plenary lectures by international luminaries addressing state-of-the-art issues

in reproductive medicine and science. We shall continue to have roundtables, videos, interactive sessions, symposia, and the popular sessions focused on menopause and contraception. During the 2013 meeting, we also plan hands-on robotic and other surgical intensives, and to focus more broadly on global applications of infertility therapies and reproductive health in low resource settings. As a conjoint meeting, our U.S. and international members will join the membership of the IFFS in reaching out to specialists in reproductive medicine worldwide to learn from each other about issues that are unique in different parts of the world and those that are common to us all. This conjoint meeting provides an opportunity to learn the latest research in the oral and poster presentations and other venues. Our many special interest and professional groups within ASRM will be presenting data that can be considered by all. The Conjoint meeting of the IFFS/ASRM in Boston 2013 will provide an opportunity to learn, to see old friends, meet new friends, and see the world of reproductive medicine through a new lens. We are developing a social program for all in Boston, a vibrant city with great historical significance in the U.S. and globally. I look forward to seeing you in Boston in 2013, as we all participating in the process of “Transforming Reproductive Medicine Worldwide!”

Sincerely,

Linda C. Giudice, M.D., Ph.D.ASRM President 2012-2013

Linda C. Giudice, M.D., Ph.D.ASRM President 2012-2013

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IFFS/ASRM CONJOINT MEETINGPROGRAM PLANNING COMMITTEE

IFFS SCIENTIFIC COMMITTEEBasil Tarlatzis (Greece), Chair

Joe Leigh Simpson (USA), President ElectLiselotte Mettler (Germany), 2010 Chair Local SC

Linda Giudice (USA), 2013 Congress ChairSerdar Bulun (USA), 2013 Chair Local SCDhiraj Gada (India), 2016 Congress Chair

Narendra Malhotra (India), 2016 Chair Local SCRichard Kennedy (UK), Secretary General, ex officio member

Paul Devroey (Belgium), Director of Medical Education, ex officio memberDavid Healy, IFFS President

IFFS SCIENTIFIC COMMITTEE MEMBER SOCIETIES Brazilian Society of Human Reproduction Artur Dzik British Fertility Society Sue Avery Finnish Gynecological Association Antti Perheentupa Japan Society of Reproductive Medicine Minoru Irahara Fertility Society of Australia Cynthia Farquhar Korean Society for Reproductive Medicine Seok Hyun Kim

AmericanSocietyforReproductiveMedicine AlanDeCherney(exofficio) AmericanSocietyforReproductiveMedicine AndrewLaBarbera(exofficio) AmericanSocietyforReproductiveMedicine RobertRebar(exofficio)

ASRM SCIENTIFIC AND POSTGRADUATE PLANNING COMMITTEESLinda C. Giudice, M.D., M.S., M.Sc., Ph.D., ASRM President

Serdar E. Bulun, M.D., Scientific Program ChairLawrence C. Layman, M.D., Interactive Sessions Chair

Kurt T. Barnhart, M.D., Roundtable Program ChairAnuja Dokras, M.D., Ph.D., Postgraduate Program Chair

Lisa M. Halvorson, M.D., Postgraduate Program Co-ChairBradley J. Van Voorhis, M.D., Postgraduate Program Coordinating Chair

G. David Ball, Ph.D., Society for Assisted Reproductive Technology Program ChairKurt T. Barnhart, M.D., Society for Reproductive Endocrinology and Infertility Program Chair

Paul J. Turek, M.D., Society for Male Reproduction and Urology Program ChairGrace M. Janik, M.D., Society of Reproductive Surgeons Program Chair

Nidhi Desai, J.D., Legal Professional Group Program ChairClaudia Pascale, Ph.D., Mental Health Professional Group Program Chair

Deborah L. Jaffe, B.S.N., Nurses’ Professional Group Program ChairThomas G. Turner, M.S., Society of Reproductive Biologists and Technologists Program Chair

Joseph J. Travia, Jr., B.S., M.B.A., Association of Reproductive Managers Program ChairCatherine Racowsky, Ph.D., Ad Hoc Member

Marcelle I. Cedars, M.D., Ad Hoc MemberRobert E. Brannigan, M.D., Ad Hoc Member

Robert W. Rebar, M.D., ASRM Executive DirectorAndrew R. La Barbera, Ph.D., H.C.L.D., ASRM Scientific Director

C. Lee Hutchison, M.A., ASRM Scientific Program CoordinatorPenelope Fenton, M.A., ASRM Postgraduate Program Coordinator

ASRM VIDEO COMMITTEESteven F. Palter, M.D., Chair

Tien-cheng A. Chang, Ph.D.Tommaso Falcone, M.D. Emilio Fernandez, M.D.

Antonio R. Gargiulo, M.D.Arik Kahane, M.D.Philip S. Li, M.D.

Stephen R. Lindheim, M.D.

Marius Meintjes, D.V.M., Ph.D.Dana A. Ohl, M.D.

David L. Olive, M.D.Marc P. Portmann, M.T.

Togas Tulandi, M.D.Paul J. Turek, M.D.

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ASRM OFFICERS Linda C. Giudice, M.D., Ph.D., President

Richard H. Reindollar, M.D., President-Elect Dolores J. Lamb, Ph.D., H.C.L.D., Immediate Past President

Roger A. Lobo, M.D., Past President Catherine Racowsky, Ph.D., H.C.L.D., Secretary

Stuart S. Howards, M.D., Treasurer

ASRM BOARD OF DIRECTORS AND THEIR MEMBER SOCIETIESMarc Fritz, M.D.

Nancy Brackett, Ph.D.Marcelle I. Cedars, M.D.

Christos Coutifaris, M.D., Ph.D.Roger A. Lobo, M.D.

Dolores J. Lamb, Ph.D., H.C.L.D.Steven Nakajima, M.D. (SREI)

Grace Janik, M.D. (SRS) Grace Centola, Ph.D., , H.C.L.D. (SMRU) Thomas Turner, Jr., E.L.D., M.S. (SRBT)

David Ball, Ph.D., H.C.L.D. (SART)

ASRM EXECUTIVE DIRECTORRobert W. Rebar, M.D.

ASRM SCIENTIFIC DIRECTORAndrew R. La Barbera, Ph.D., H.C.L.D.

IFFS OFFICERS AND BOARD OF DIRECTORS 2010 - 2013

IFFS OFFICERSDavid Healy (Australia), President

Joe Leigh Simpson (USA), President ElectRichard Kennedy (UK), Secretary General

Gabriel de Candolle (Switzerland), Assistant Secretary GeneralEdgar Mocanu (Ireland), Treasurer

Mauricio Abrao (Brazil), Assistant TreasurerBasil Tarlatzis (Greece), Past President

Paul Devroey (Belgium), Director of Medical Education

IFFS BOARD OF DIRECTORS AND THEIR MEMBER SOCIETIES American Society for Reproductive Medicine G. David Adamson 2007-2016 Argentine Society for Reproductive Medicine Marcos Horton 2010-2019 Colombian Association of Fertility and Jose Ignacio Madero 2004-2013 Reproductive Medicine Fertility Society of Australia Ossie Petrucco 2004-2013 German Society of Reproductive Medicine Tina Buchholz 2004-2013 Indian Society of Assisted Reproduction Dhiraj Gada 2010-2019 Japan Society of Reproductive Medicine Minoru Irahara 2007-2016 Jordanian Society for Fertility and Genetics Mazen El-Zibdeh 2010-2019 Swedish Society of Obstetrics and Gynecology Pietro Gambadauro 2007-2016

ASRM OFFICERS AND BOARD OF DIRECTORS 2012 - 2013

IFFS/ASRM Annual Meeting Policies and DisclaimersCANCELLATION POLICYThe International Federation of Fertility Societies and the American Society for Reproductive Medicine reserve the right to cancel this activity due to unforeseen circumstances. In the event of such cancellation, the full enrollment fee will be returned to the registrant.

REFUND/NON-ATTENDANCE POLICYCancellations received before or by September 12th will receive a full refund minus a $50 processing fee. Cancellations received after September 12th will not be eligible for a refund.

ADA STATEMENTThe International Federation of Fertility Societies and the American Society for Reproductive Medicine fully comply with the legal requirements of the ADA and the rules and regulations thereof. Accommodations for Disabilities: Please notify the American Society for Reproductive Medicine, 1209 Montgomery Highway, Birmingham, Alabama, USA 35216, telephone 1-205-978-5000, a minimum of 10 working days in advance of the event if a reasonable accommodation for a disability is needed.

EQUAL OPPORTUNITY STATEMENTThe International Federation of Fertility Societies and the American Society for Reproductive Medicine value and promote diversityamongitsmembers,officersandstaff.TheSocietiesprohibitdiscriminationtowardanymemberoremployeedueto race, color, religion, age, gender, sexual orientation, national origin, citizenship, disability, military status or other basis prohibited by law. IFFS and ASRM strive to achieve gender, racial and ethnic balance in hiring and governance. IFFS and ASRM maintain policies, procedures and personnel actions that conform to the letter and spirit of all laws and regulations pertainingtoequalopportunityandnondiscriminationinemployment,appointmentsandelectionstooffice.

DISCLAIMER STATEMENTThecontentandviewspresentedinthiseducationalactivityarethoseofthefaculty/authorsanddonotnecessarilyreflectthose of the International Federation of Fertility Societies and the American Society for Reproductive Medicine. This material is prepared based upon a review of multiple sources of information, but it is not exhaustive of the subject matter. Therefore, healthcare professionals and other individuals should review and consider other publications and materials on the subject matter before relying solely upon the information contained within this educational activity to make clinical decisions about individual patients.

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Registration & Meeting Information

8 Register online @ www.asrm.org and receive immediate confirmation!

! On-site in Boston, MA Choices may be limited on-site. Pre-registration is recommended.

On-Site Registration Desk: Boston Convention and Exposition Center

How to Register

Be Sure to Visit the Exhibit Hall

For the safety of your child and in order to maintain the scientific nature of the display, no children under the age of 16 (except infants under 6 months of age carried in arms at all times) will be allowed in the Exhibit Hall.

Strollers and infants in backpacks are not permitted in the Exhibit Hall or Poster Hall at anytime.

Friday, October 11 . . . . . . . . . . . 2:00 p.m. – 7:00 p.m.Saturday, October 12 . . . . . . . . . 7:00 a.m. – 7:00 p.m.Sunday, October 13 . . . . . . . . . . 7:00 a.m. – 7:00 p.m.Monday, October 14 . . . . . . . . . . 7:00 a.m. – 5:00 p.m.Tuesday, October 15 . . . . . . . . . 7:00 a.m. – 5:00 p.m.Wednesday, October 16 . . . . . . . . 7:00 a.m. – 5:00 p.m.Thursday, October 17 . . . . . . . . . 7:00 a.m. – 1:00 p.m.

Sunday, October 13 . . . . . . . . . 7:30 p.m.- 9:30 p.m.

Monday, October 14 . . . . . . . . . 9:00 a.m.- 5:00 p.m.

Tuesday, October 15 . . . . . . . . . 9:00 a.m.- 5:00 p.m.

Wednesday, October 16 . . . . . . 9:00 a.m.- 5:00 p.m.

Thursday, October 17 . . . . . . . . . . . . . . 9:00 a.m.- 12:00 p.m.

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Individual Registration for the 2013 IFFS/ASRM Annual Meeting opens April 30, 2012.

Group Registration for the 2013 IFFS/ASRM Annual Meetingopens April 30, 2012.

To register, visit:

www.asrm.organd click on “Annual Meeting” and

then “Register for 2013 Annual Meeting.”

Use your 2013 IFFS/ASRM First Program as a guide inregistering for the courses you wish to attend.

For questions, please call (866) 471-7224 or (703) 449-6418or email [email protected].

Register early to take advantage of discounted rates!Early Bird Deadline 7/12/2013 • Advanced Deadline 9/14/2013

Registration Information Book in the IFFS/ASRM Housing Block and

save $50 off Registration fees!

Cancellations received before or by September 12, 2013will receive a full refund minus a $50 processing fee.

Cancellations received after September 12, 2013will not be eligible for a refund.

CERTIFICATE OF ATTENDANCEProof of attendance is available on request from J. Spargo at the registration desk. Continuing Education Credit information is located in the front of the Postgraduate Course syllabi, and the Final Program and online.

ADMISSION BADGESNamebadgeswillbeissuedforthePostgraduateandScientificProgramsandarerequiredforadmission.Spouse/guestbadges will be issued and are required for admission to spouse/guest activities and the Exhibit Hall.

PHOTO/AUDIO/VIDEO RECORDINGPhotographing or audio/video recording of any session for personal or commercial purposes without permission is prohibited.

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Registration Information POSTGRADUATE COURSE REGISTRATION FEES

Early Bird Advanced Onsite By By After 7/11/2013 9/12/2013 9/12/2013

ASRM Member (Doctoral)

One 1-day course $320 $350 $380

Two 1-day courses $580 $640 $700

One 2-day course $540 $600 $660

ASRM Member (Non-Doctoral)

One 1-day course $220 $240 $260


One 2-day course $380 $420 $460

Non-ASRM Member (Doctoral)

One 1-day course $380 $420 $460


One 2-day course $650 $720 $790

Non- ASRM Member (Non-Doctoral)

One 1-day course $270 $300 $330


One 2-day course $450 $500 $550

Medical Resident-In-Training, Fellow, Team Member from your office/practiceOne 1-day course $220 $240 $260


One 2-day course $380 $420 $460

SRS Hands-on Postgraduate Courses $300 additional charge will apply

SCIENTIFIC PROGRAM REGISTRATION FEES

Early Bird Advanced Onsite By By After 7/11/2013 9/12/2013 9/12/2013

ASRM Member $595 $695 $795 (Doctoral)

ASRM Member $495 $545 $595 (Non-Doctoral)

ASRM Life Member $495 $545 $595

Fellow $495 $545 $595(proof of status letter from chair/dept. head required)

Non- ASRM Member $795 $895 $995(Doctoral)

Non- ASRM Member $495 $545 $595(Non-Doctoral)

Team Member from $495 $545 $595your Office/Practice

Medical $250 $250 $250Resident-In-Training

Full-time Student $250 $250 $250(Full-time medical students and full-time graduate students working toward first doctorate; Documentation required)

Developing Countries** $545 $620 $695

Spouse/Guest Program $100 $100 $100(Spouse/Guest registration includes Opening Reception, Exhibit Hall, Plenary Sessions & Hospitality)

TICKETED EVENTS

Roundtable Luncheons $50/dayYou may attend only one Roundtable Luncheon per day.

Women’s $30Council BreakfastWednesday, October 16, 2013 at 7:30 a.m.

Museum Night $125Wednesday, October 16, 2013 at 7:00 p.m.

**Individuals from the following countries will receive a discounted rate on registration: Afghanistan, Bangladesh, Benin, Burkina Faso, Burundi, Cambodia, Central African Republic, Chad, Comoros, Democratic Republic of the Congo, Eritrea, Ethiopia, Gambia, Guinea, Guinea-Bissau, Haiti, Kenya, Democratic Republic of Korea, Kyrgyz Republic, Liberia, Madagascar, Malawi, Mali, Mozambique, Myanmar, Nepal, Niger, Rwanda, Sierra Leone, Somalia, Tajikistan, Tanzania, Togo, Uganda and Zimbabwe

Morning Poster SessionsPoster Sessions will be held on Tuesday, Wednesday, and Thursday

mornings from 7:00 a.m. until 9:00 a.m.

Complimentary continental breakfast will be available.No reservation is required.

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Housing InformationBook in the IFFS/ASRM Housing Block and

SAVE $50 off Registration fees!To book housing for the 2013 IFFS/ASRM Annual Meeting, visit www.asrm.org

Click on “Annual Meeting” and then the appropriate housing link.For questions, please call (866) 471-7224 or (703) 449-6418 or

email [email protected]

1. Boston Park Plaza

$285.00 Single (1 person/1 bed)

$285.00 Double (2 people/1 bed)

$285.00 Double/Double(2 people/2 beds)

$305.00 Triple (3 people/2 beds)

$325.00 Quad (4 people/2 beds)

2. Boston Marriott Copley Place






3. Courtyard Boston Downtown/Tremont






4. Fairmont Copley Plaza






5. Hilton Boston Financial District






6. Hyatt Regency Boston






7. Omni Parker House Hotel






8. Renaissance Boston Waterfront






9. Seaport Hotel






10. Sheraton Boston



$299.00Double/Double(2 people/2 beds)



11. Westin Boston Waterfront(Headquarters Hotel)






12. Westin Copley Plaza






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Boston Hotel Map20

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Disclosure Statements/Conflict of Interest Policy

2013 IFFS/ASRM Conflict of Interest Policy for Invited SpeakersHonoraria

The following speakers may receivehonoraria and/or discounted or freeregistration:

•PlenarySpeakers•PostgraduateCourseFaculty•TrilogySpeakers•SymposiaSpeakers•InteractiveSessionSpeakers

The following speakers do not receive honoraria:

•RoundtablePresenters•AbstractPresenters•VideoPresenters

Disclosure StatementsPostgraduate Faculty, Symposia Speakers, Plenary Lecturers, Abstract Authors, Abstract Graders, Round-table Presenters, Video Presenters, and Interactive Speakers are required to disclose commercial relationships or other activities that might be perceived as potential conflictsofinterest.

Postgraduate course faculty disclosures will be listed in the course syllabi.

Symposium speakers’ disclosures will be presented in handout materials, as well as on slides.

Disclosures from speakers in the Plenary Sessions, Interactive Sessions, Roundtables, Videos and Symposia will be published in the Final Program.

Abstract authors’ disclosures will be published in the 2013 Program Supplement.

Each presenter should reveal his/her disclosure information during his/her presentation, preferably with the visual aid of a slide.

Roundtable presenters should provide a copy of their disclosure forms to the participants at their table.

As a provider of continuing medical education (CME) accredited by the Accreditation Council for Continuing Medical Education (ACCME), the American Society for Reproductive Medicine must ensure balance, independence,objectivityandscientificrigorinallitseducationalactivities.Allpresentersmustdisclosetothelearnersanycommercialorfinancialinterests and/or other relationships with manufacturers of pharmaceuticals, laboratory supplies and/or medical devices. All relationships, whether or not they directly apply to this CME event, must be disclosed. All non-FDA approvedusesofproductsmustbeclearlyidentified.Disclosuresmaybemade in the form of a slide, printed material, or oral statement.

The intent of this disclosure is not to prevent a speaker with a commercial or financialinterestfrommakingapresentation.TheintentistoassistASRMinresolvingconflictsofinterestandtoprovidelearnerswithinformationonwhich they can make their own judgments regarding any bias. Although ASRMreviewsandresolvespotentialconflictsofinterest,itremainsfortheaudience to determine whether the speaker’s interests or relationships may influencethepresentationwith regard to exposition or conclusion.

Disclosures will be revealed to the learners. For postgraduate courses, disclosure information will be provided in the syllabus. For other activities, where no syllabus or other similar printed material is available, disclosures must be made verbally to the audience by the speakers, preferably with the visual aid of a slide.

Forthosesituationswherethereisnopotentialforconflictofinterest,theportion of the form that so states should be completed. In those situations where a speaker does not complete a form or refuses to complete a form, the individual is ineligible to participate as a speaker in the CME activity.

Speakers should also reveal to the audience any “off label” uses (not approved by the FDA) of any drugs or products discussed.

Abstract authors’ disclosures are listed in the 2013 Program Supplement.

Speakers in the Symposia and Interactive, Video, Roundtable and Abstract

Sessions have also complied with ASRM policies and their disclosures are printed

in the ASRM Final Program. The speaker should reveal this information during

his/her presentation, preferably with the visual aid of a slide.

Continuing Medical Education andContinuing Education Credits will be available.

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46TH ANNUAL POSTGRADUATE

PROGRAM COMMITTEE

CHAIRAnuja Dokras, M.D., Ph.D.

CO-CHAIRLisa M. Halvorson, M.D., Ph.D.

COORDINATING CHAIRBradley J. Van Voorhis, M.D.

WEEKEND COURSESDates:

Saturday, October 12TH

Sunday, October 13ST

Hours:8:15 a.m.-5:00 p.m.

Lunch is from Noon-1:00 p.m.

Courses PG1-PG12 are one-day courses on Saturday.

Courses PG13-PG26 are one-day courses on Sunday.

Course PG27 is a two-day courseon Saturday and Sunday.

Postgraduate Course Syllabi will be posted

online in September 2013.

Printed copies will be distributed on-site.

Postgraduate ProgramOne-Day Courses

Saturday, October 12, 2013

GLOBAL APPROACHES TO PREVENTING INFECTIONSIN THE ART LABORATORY: FROM THEORY TO PRACTICE

Course PG1 (Saturday)

Developed in Cooperation with the International Federation of Fertility Societies

FACULTYDeborah J. Anderson, Ph.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONDifferent regions of the world have different infections in the population that impact the practice of assisted reproductive technologies. The challenge for laboratory and clinical staff of ART clinics is to prevent transmission of infectious agents to the mother or gestational carrier and to the offspring of ART procedures. The objective of this live course is to train all members of the professional ART team to implement clinical and laboratory procedures to reduce the risk of transmission of infectious agents.

ACGME CompetencyPatient care

LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Summarize the prevalence and characteristics of concern in different populations around the world.2. Design and implement practices to prevent infection in ART clinics in developed countries.3. Discuss implementation of procedures to prevent infection in ART clinics in developing countries.

CODING FOR REPRODUCTIVE MEDICINE PRACTICES 2013Course PG2 (Saturday)

Developed in Cooperation with the American Society for Reproductive Medicine Coding Committee

FACULTYJohn T. Queenan Jr., M.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONEveryreproductivemedicinepracticehasalegalandethicalobligationtofollowaspecificset of rules and regulations that determine how reimbursements are calculated. Failure to follow these rules can result in unfair practices to patients and/or legal consequences from government or third-party payers. The problem is those rules and regulations have become so complex that most people cannot understand them without receiving special training. This livecourse,designed forphysicians,practicemanagers,billers,officemanagers,sonographers, laboratory managers, and physician assistants, will include didactic lectures, panel discussions, case presentations and interactive question and answer sessions. The correct way to report diagnostic codes and select the appropriate procedure codes will be explained, with a focus on quality improvement and minimizing errors. Systems-based resources available to aid in improving patient billing accuracy will be addressed, as will information technology resources that provide participants with the ability to continue updating their knowledge of correct coding in the future. Special attention will be given to theupcomingchangesintheInternationalStatisticalClassificationofDiseasesandRelatedHealth Problems (ICD), 10th Revision.

ACGME CompetencySystems-based practiceLEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:

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46TH ANNUAL POSTGRADUATE PROGRAM

COMPLICATIONS OF ART: IN SEARCH OF A HAPPY ENDINGCourse PG3 (Saturday)

Developed in Cooperation with the Nurses’ Professional Group

FACULTYAngela Smith, N.P., ChairTamara M. Tobias, A.R.N.P., Co-Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONThe successful outcome of fertility treatment brings joy to many couples. Unfortunately, some treatments result in complications that present complex issues and require special management strategies. These may include ovarian hyperstimulation syndrome (OHSS), ectopicpregnancy,pregnancyloss,multiplepregnancyandtreatmentfailure.Thedecisiontousethird-partyreproductionmaybedifficultand other psychological complications such as depression, isolation and relationship strain may add additional obstacles. Healthcare providers must understand the problems that may occur, discuss treatment and management strategies, and recognize when referrals or other resources are needed. The factors that may prevent or reduce the risk of ovarian hyperstimulation syndrome and management strategies for ectopic and multifetal pregnancy will be addressed in this course. The psychological complications of pregnancy loss and treatment failure will be examined. In addition, the psychosocial issues of third-party reproduction, depression, isolation and relationship stressors will be explored. The goal of this live course is to increase the ability of nursing professionals to avoid potential complications of fertility treatment and to provide patients with strategies to navigate their fertility journeys.

ACGME CompetencyPractice-based learning and improvement

LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Discuss OHSS and various strategies to prevent this syndrome and the effectiveness of those strategies.2. Review the management and impact of an ectopic pregnancy.3.Exploretheemotionalinfluenceoftreatmentfailureandpregnancyloss.4. Explain the unique issues confronting multifetal pregnancies and current treatment strategies.5. Examine the psychological implications of third-party reproduction, depression, isolation and relationship stressors which may ensue from fertility treatment.

1. Demonstrate correct coding of diagnostic conditions that are typically encountered in the practice of reproductive endocrinology.2. Identify the correct Current Procedural Terminology (CPT) code for surgical procedures encountered in the practice of reproductive

endocrinology and list additional resources available to aid with correct coding procedures in the future.3. Summarize the rules and regulations required by third-party payers regarding documentation guidelines to verify that physician

services were rendered according to medical necessity and in accordance with the requirements of CPT. 4. Describetheproperstepsforsuccessfulverificationornegotiationofcoverageinobtainingthird-partypayercoverageforfertility

services.

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Developed in Cooperation with the Society of Reproductive Biologists and Technologists

FACULTYMarybeth Gerrity, Ph.D., M.B.A., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONCryopreservation of reproductive cells and tissues has been practiced for more than half a century. However, lack of consensus on best practices has led to variable cryopreservation success rates that may hamper clinical utilization. While human sperm has been cryopreservedfordecades,techniquessuchasoocytevitrificationarerelativelyrecenttechnologybreakthroughs.Thelearningcurveforsome of these techniques can be steep and best practices for how to determine a laboratory’s competence to perform the procedures are still evolving. As the types of patients who are candidates for cryopreservation procedures expand beyond fertility patients to include those with chronic diseases, it may not be feasible to mount multiple attempts at cryopreservation. Optimizing outcomes from the outset will be critical. Review of the Society for Assisted Reproductive Technology (SART) outcome statistics indicate the outcomes with cryopreservation of embryos vary by center, and strategies for assessing the cause of the variability must be developed before the technique is offered to patients who may have only one chance for a successful outcome (e.g., cancer patients). At the same time, long-term storage of these frozen cells and tissues presents challenges to long-term success. Cells formerly stored for several years may now be stored for decades. As frozen egg banks become more common, the lessons learned from years of sperm banking should not be lost and good tissue-banking practices must be implemented. Finally, experimental techniques that broaden the types of tissues that can be cryopreserved are in use at some centers. Knowledge of these methods, including their strengths, weaknesses and limitations, is essential in determining if they are safeandefficaciousandreadytomoveintowidespreaduseorshouldbereservedforspecializedcenters.Thislivecourseforlaboratoryclinicians will cover current cryopreservation techniques and their application outside of infertility treatment, instituting competency-based training in laboratories, and issues of long-term storage of cells and tissues.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Describe the scope of the clinical use of cryopreservation of reproductive tissues and cells outside of infertility treatment.2. Assess the best methods for cryopreservation according to tissue type, including factors that can limit success.3. Design a plan for competency-based training that can be instituted for each cell or tissue type. 4.Discusstheuniquetechnical,financial,logisticalandregulatorychallengesoflong-termstorageofreproductivecellsand tissues.5. Compare and contrast the practice of long-term banking of anonymous sperm donors with that of egg donors and answer the question, “What can egg banks learn from sperm banks?”

CRYOPRESERVATION OF REPRODUCTIVE CELLS AND TISSUES:REAL WORLD APPROACHES AND LABORATORY PEARLS


A SIMPLIFIED RISK-FREE IVF WITHOUT COMPROMISING OUTCOMECourse PG5 (Saturday)

Developed in Cooperation with the Middle East Fertility Society

FACULTYMohamed Aboulghar, M.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONThe success of in vitro fertilization (IVF) is affected by patients’ reproductive status, the stimulation protocol and the quality of gametes and embryos. These parameters can vary greatly among IVF clinics. It is necessary to optimize the clinical and laboratory procedures to ensure the highest quality embryos. This live course for physicians, nurses and laboratory staff of IVF clinics is designed to highlight the latest medical evidence in assisted reproductive technology. The course will describe how to simplify the IVF procedure beginning with stimulation protocols. The faculty will address minimal monitoring, newer options for triggering ovulation, assuring safety of IVF by prevention of ovarian hyperstimulation syndrome (OHSS) and multiple pregnancy, and simplifying the laboratory and freezing procedures without reducing the pregnancy rate.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Perform natural- and clomiphene-cycle IVF.2. Describe the soft protocols for ovarian stimulation in IVF.3. Explore newer options for triggering ovulation with minimum risk.4. Avoid OHSS in performing IVF.5.Discussthebenefitsandrisksofsingle-embryotransferandcryopreservation.

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BRIDGING THE GAP BETWEEN SCIENCE AND CLINICAL CARE INENDOMETRIOSIS-RELATED INFERTILITY


Developed in Cooperation with the Endometriosis Special Interest Group

FACULTYHugh S. Taylor, M.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONEndometriosis is a highly prevalent disease. However, there are many gaps in physicians’ competence to diagnose patients with endometriosis. This disease places a tremendous burden on society, both economically and related to quality of life. The principal manifestations of this disease, which causes both infertility and chronic pain, mandate that all general gynecologists and subspecialists be involved in the care of these patients. This live course is designed to improve physicians’ competence in the medical and surgical management of endometriosis. Topics to be discussed include: pathophysiology of endometriosis-associated pain syndromes; pathophysiology of endometriosis-associated infertility; choosing an appropriate medical or surgical therapy; technical aspects of surgical approaches; in vitro fertilization (IVF) approaches, including pre-IVF optimization; and new genetic etiologies of endometriosis. Coherent summaries with key learning points will be provided and reinforced during the session of case reports.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Discuss clinical implications of the pathophysiology of endometriosis in patients with infertility.2. Explain the new genetic etiologies for endometriosis and ways to identify those at risk.3. Describe the options for managing endometriosis before an IVF cycle.4. Summarize the optimal approach for an IVF cycle in a woman with endometriosis.

Developed in Cooperation with the American Institute of Ultrasound in Medicine and the Imaging in Reproductive Medicine Special Interest Group

FACULTYLaurel A. Stadtmauer, M.D., Ph.D., ChairTodd Deutch, M.D., Co-Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONUltrasound has become the most widely used and important tool in diagnosis and treatment of infertility. Ultrasound and ultrasound-guided procedures have become integral components not just of assisted reproductive technology (ART), but also in the day-to-day practice of reproductive medicine, infertility and gynecology. 3-D ultrasound allows better imaging, as well as more accurate volume rendering. It has become the gold standard for the diagnosis of uterine anomalies, and may assist in more accurate follicular monitoring measurements. In 2009, new practice guidelines for ultrasound in reproductive medicine were published by the American Institute of Ultrasound in Medicine (AIUM) and in collaboration with the American Society for Reproductive Medicine (ASRM). Surveys of members of the Society for Reproductive Endocrinology and Infertility, the Imaging Special Interest Group and ASRM have revealed a strong desire for CME credits in ultrasonography that would prepare reproductive medicine professionals and gynecologists for accreditation by AIUM. In addition, there is an interest in training and credentialing reproductive nurses and nurse practitioners to perform limited ultrasounds in theoffice. This live one-day course, designed to meet the needs of physicians and other healthcare providers who use gynecologic sonography, will fulfillCMErequirements forAIUMcredentialing.Theobjectiveof thiscourse is toprovideacomprehensivesurveyof theuseofultrasonography in the female pelvis for physicians, nurses and ultrasonographers actively involved in reproductive medicine, infertility and gynecology. This course will emphasize the use of ultrasound in maximizing ART success and including follicular monitoring with 3-D sonographic automatic volume calculation, assessment of the uterine lining during retrieval and embryo transfer in an evidence-based manner. Newer technologies, such as 3-D ultrasound, Doppler and the use of CT- and MRI-guided procedures, will also be discussed, along with cost-effective current or potential applications. Participants will be encouraged to actively take part in case presentations and discussions of controversies. Practical applications of the technology will be addressed along with case presentations, and participants will have the opportunity to manipulate 3-D images.

ULTRASOUND IMAGING IN ARTCourse PG7 (Saturday)

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LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Summarize the appropriate use of ultrasonography in the evaluation of infertility, uterine abnormalities and the pathology of the reproductive tract.2.Describetheproperassessmentofearlypregnancyandlistfindingsonearlypregnancyassessmentsthatareassociated with poor outcome.3.Discusstheimportanceof3-Dultrasonographyinreproductivemedicine,andtheimportanceofDopplerblood-flow assessment in reproductive medicine and gynecology.4. Evaluate the use of fallopian tube patency with ultrasound.5. Critically evaluate how ultrasound can maximize the success of ART.

CRITERIA FOR WORLD-CLASS PERFORMANCE EXCELLENCECourse PG8 (Saturday)


Developed in Cooperation with the Association of Reproductive Managers

FACULTY Joseph J. Travia, Jr., B.S., M.B.A., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONReproductive medicine facilities are confronted with more challenges than ever before from patients expecting world-class service and results. With slower annual growth and a competing global economy, being good is no longer an option; patients want the best. Patients are well informed through social media and other Internet resources, and their expectations for good outcomes continue to rise. Their initial selection of a clinic will be based on cutting-edge technology and published results. If patients remain with their initial selection, thatdecisionwillbebasedonthelevelofservicetheyreceivedduringtheirfirstvisit.Scientificbreakthroughscontinuetoprovidenewopportunities for meeting the needs of assisted reproductive technology (ART) patients world-wide. This live course is designed for practitioners wanting to create a world-class experience for their patients through performance excellence at every level of their organization. From creative leadership, strategic planning, patient focus, measurement, analysis and knowledge managementtoworkenvironmentandemployeeengagement,thiscoursewillenableeveryparticipanttocontributesignificantlytotheirpractice's reach for excellence.

ACGME CompetencySystems-based practice

LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Formulate the critical logistics of strategic planning and implementation, with a focus on patient recruitment and retention.2. Convert strategic objectives into action plans, along with key action plan indicators to measure competency and performance results in the practice.3. Provide a world-class work environment that promotes creative leadership and employee engagement.4. Determine the best, most competitive healthcare service offerings for the practice, and the most effective patient and stakeholder communication vehicles to market those opportunities.5. Measure, analyze, review and improve performance at all levels of the organization through the information already available in clinical, laboratory, and operations databases.

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THE ART OF GENETICS: REPRODUCTIVE GENETICS IN THE ART SETTINGCourse PG9 (Saturday)


Developed in Cooperation with the Genetic Counseling Special Interest Group

FACULTYJill M. Fischer, M.S., C.G.C., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONReproductive genetics is an increasing part of the assisted reproductive technology (ART) practice. Daily, ART centers use genetic information when couples undergo ethnicity screening, when donors are screened and chosen for recipient couples, to determine the cause of infertility or recurrent pregnancy loss, and when utilizing preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD). However, the application of genetic information and genetic testing is often limited due to lack of knowledge by the medical providers in the ART practice. Education of these medical providers is incomplete and most ART centers do not have a genetic counselor on staff. This livecourseserves toprovidebasic tocomplexgenetic information tohelpsuchpracticesstart tofill thiseducationgapandcompetently apply genetic information to improve patient care. The course will provide both basic genetics education and review of real timeapplication.Thefacultywilladdresscurrentknowledgeofthegeneticcausesofmaleinfertilitynotlimitedtocysticfibrosisandgeneticcauses of female infertility, including the latest research on and testing for fragile X syndrome. As high throughput carrier testing options become more readily available, current American Society for Reproductive Medicine (ASRM), American College of Obstetricians and Gynecologists (ACOG) and American College of Medical Genetics (ACMG) carrier testing guidelines will be outlined and the application of such testing discussed. Current PGS/PGD test techniques and applications will be examined. Overall, this course should educate the ART medical professionals on current genetic information and test options so they can improve patient care in their practices.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Explain genetic inheritance patterns, risk assessment and ethnicity screening.2. Describe genetic and chromosomal causes of male and female infertility and infertility test options.3.Definegeneticandchromosomaltestoptionsforrecurrentpregnancy-losspatients.4. Outline donor carrier screening guidelines by ASRM, ACOG and ACMG and their application to current practice.5. Evaluate the value of high throughput carrier screening in the ART setting and review current test techniques and applications of PGD.

Developed in Cooperation with the Mental Health Professional Group

FACULTYAndrea Mechanick Braverman, Ph.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONThe idea of Mommy and Daddy and baby makes three as depicted in the 1950s “Leave it to Beaver” representation of the family has been put into rerun by the new American family of “Modern Family” and “Two and a Half Men.” Many of the new families are made possible only by assisted reproductive technology (ART). Single mothers by choice and single fathers by choice are emerging as “choice” families. Co-in vitro fertilization (IVF) with lesbian partners sharing the genetic and gestational contribution to their children is now a common procedure. On the horizon are families where Mom freezes her eggs in her 20s or 30s but is now ready to fertilize an egg and get pregnant in her 40s and 50s. This live course will increase mental health professionals’ understanding of the many new ART families. This course will provide participants with the current research and theories explaining the needs and challenges for these families. Utilizing an interactive format of a mock trial, participants will have the opportunity to hear “testimony” and be “the jury” to identify the issues and concerns of these ART families. This course will equip mental health professionals in providing competent understanding and sensitivity to the ever-expanding All-American family.

ACGME CompetencyInterpersonal and communication skills

LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Describe the different types of families made possible by ART.2. Discuss the current literature on the new ART families.3. Explain the challenges to providers in counseling these new ART families.

NEW FAMILIES ON TRIALCourse PG10 (Saturday)

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Developed in Cooperation with the Society for Assisted Reproductive Technology

FACULTYJames M. Goldfarb, M.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONThird-party reproduction, particularly oocyte donation (OD) and gestational surrogacy (GS), has received much professional and public attention recently. Both of these procedures have been utilized since the mid-1980s, but as they have evolved, the medical, legal and psychological/ethical complexities have all increased. It is imperative that individuals involved with these procedures be aware of all the complex issues involved. Embryo donation (ED) and sperm donor insemination (DI) have attracted less attention and are medically not ascomplexasODandGS.However,they,too,areassociatedwithsignificantlegalandpsychological/ethicalissues. This live course, designed for medical professionals involved in assisted reproductive technology (ART), examines the medical, legal and psychological/ethical issues involved in OD and GS, and to a lesser extent, ED and DI. Medical topics to be discussed include: safety considerations and inclusion/exclusion criteria for egg and sperm donors and gestational surrogates, number of embryos to transfer in egg and embryo donor and gestational surrogate cycles, and role of oocyte cryopreservation in OD cycles. Legal topics will include: model legislation by the American Bar Association, variation in regulation of third-party reproduction in different states, new legislative proposals to regulate third-party reproduction, informed consent and legal pitfalls. Psychological/ethical issues will include: egg donor and gestational surrogate payment, participant coercion, shared egg donation, divulging to offspring, and psychological aspects and screening tools of third-party reproduction.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Explain the legal issues regarding OD, GS, ED and DI, particularly regarding state legislative efforts to regulate third-party reproduction.2. Discuss issues with egg donation, including establishment of a national egg donor registry, differences between anonymous and directed egg donation, and guidelines for payment of egg donors.3. Summarize the status of cross-border reproductive care as it relates to OD and GS.

ENDOMETRIUM AND EMBRYO CROSS-TALK:HOW TO PREDICT AND ACHIEVE IMPLANTATION SUCCESS


Developed in Cooperation with the European Society of Human Reproduction and Embryology

FACULTYAntonis Makrigiannakis, M.D., Ph.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONDuring implantation, the cross-talk between the embryo and the endometrium remains largely unknown. Local and systemic players interact for the achievement of human pregnancy. Impaired implantation is currently considered the most important limiting factor for the establishment of viable pregnancies in assisted reproduction. It is expected that elucidating the molecular background of the process will enable accurate diagnosis and effective treatment of implantation failure and/or miscarriages. The purpose of this live course for embryologists and clinical reproductive medicine specialists is to identify factors that predict implantation success and investigate potential treatment modalities to manage implantation failure and/or miscarriages.

ACGME CompetencyMedical knowledge

LEARNING OBJECTIVES At the conclusion of this course, participants should be able to: 1. Summarize the physiology and pathophysiology of implantation.2. Describe local and systemic factors leading to miscarriages and/or implantation failure.3. Discuss the challenges of predicting and achieving implantation success.

THIRD PARTY REPRODUCTION IN THE UNITED STATES:LEGAL, MEDICAL AND PSYCHOLOGICAL/ETHICAL ASPECTS


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PCOS: CARING FOR A WOMAN OVER HER LIFETIMECourse PG13 (Sunday)


Developed in Cooperation with the Society for Reproductive Endocrinology and Infertility

FACULTYKurt T. Barnhart, M.D., M.S.C.E., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONPolycystic ovary syndrome (PCOS) is the most common endocrine disorder in females of reproductive age and is highly prevalent. The etiology of this heterogeneous condition remains obscure and its phenotype expression varies. PCOS affects many aspects of a woman’s life and this live course will supply the reproductive endocrinologist and general gynecologist with the latest information on PCOS in order to provide up-to-date recommendations for patient care. Topics to be covered will include how PCOS affects reproductive health over a woman’s lifespan, hirsutism and acne, contraception, fertility, menstrual cycle abnormalities, quality of life, ethnicity, pregnancy complications,long-termmetabolicandcardiovascularhealthand,finally,cancerrisk.InformationwillincludematerialfromThe Consensus on Women’s Health Aspects of Polycystic Ovary Syndrome.

ACGME CompetencyPractice-based learning and improvement

LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Contrast the signs and symptoms of PCOS in women of different ages and ethnicities. 2. Interpret how aspects of the phenotype of PCOS correlate with risk factors for insulin resistance, diabetes mellitus (DM) type II and cardiovascular health. 3. Develop a practical approach to testing for precursors of DM and cardiovascular disease in women with PCOS.4. Distinguish the medical and reproductive needs of a women with PCOS based on where she is in her lifetime.

One-Day CoursesSunday, October 13, 2013

CROSSING BORDERS AND OTHER HOT LEGAL ISSUES FOR THEHEALTHCARE PROVIDER AND LEGAL PRACTITIONER

Course PG14 (Sunday)

Developed in Cooperation with the Legal Professional Group

FACULTYNidhi Desai, J.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONThe involvement of third parties in assisted reproduction as gamete and embryo donors and as gestational carriers has produced a plethora of legal issues for the reproductive healthcare professional. Confronted with the complicated relationships among intended parents, gamete donors and gestational surrogates, the medical team often does not appreciate the legal implications of treating patients from different countries. While medical practitioners should not offer legal advice, awareness of the legal complexities and possible landmines their patients may encounter with respect to immigration, contract enfoceability and parentage will help better serve practices and patients. Recognition of those arrangements that require a partnership of legal and medical experts is essential in the creation of legally-secure families. The medical practitioner often has a lack of understanding of legal issues related to developments in new technologies and the interaction of the laws of various jurisdictions when treating or advising international clients. This live course will provide guidance to the healthcare practitioner and lawyer advising patients who are traveling from other countries as well as those patients traveling out of the United States for treatment. Topics will include treatment, parentage, immigration, and contract enforceability given the intersection of multiple jurisdictions. The course will further explore current hot topics in assisted reproductive technology such as egg freezing and international regulations. This presentation is designed to review commonly-encountered situations that are subject to legal scrutiny, define the legal issues and potential pitfalls, provide practical solutions to roadblocks in assistedreproductivetechnologyarrangementsandexplorethelegalsignificanceoftreatingclientsfromothercountries.Thevariousspeakerswillfurtheraddressissuesemergingasaresultofnewertechnologybasedonlegalprecedentandprinciples.Eachpresenterwillfieldquestions from attendees that will allow for discussion of particular clinical conundrums, with the opportunity to develop usable solutions forclinicalpractice.Thisprogramwillfeatureapracticalapproachtohelplawyersandphysiciansbetterfieldsituationsastheyarise.


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46TH ANNUAL POSTGRADUATE PROGRAMLEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Explain problematic issues arising out of cross-border care.2.Constructspecificstepsforclinicstotaketoprotecttheirprogramsandpatients.3. Discuss some of the emerging legal challenges brought on by newer assisted reproductive technologies.4. Formulate practical methods of dealing with these emerging issues.

LEIOMYOMATA: CLINICAL UPDATES, RESEARCH DEVELOPMENTS ANDDISPARITIES IN DISEASE, OUTCOMES AND ACCESS TO CARE


Developed in Cooperation with the Fibroid Special Interest Group and the Health Disparities Special Interest Group

FACULTYGloria Richard-Davis, M.D., ChairAyman Al-Hendy, M.D., Ph.D., Co-Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONUterineleiomyomata(fibroids),benignestrogen-dependenttumorsoftheuterinewall,areacommoncauseofacuteandchronicpelvicpaininwomen.Uterinefibroidsaffect40-80%ofwomenofreproductiveageandaretheleadingindicationforhysterectomyinAfrican-American women. More than 600,000 hysterectomies were done in the United States in 2000 because of leiomyomata. At a mean cost of$8billionperyear,African-Americanwomenareparticularlyaffectedastheprevalenceofuterinefibroidsisaboutthreetimeshigherinthat ethnic group compared with Caucasians. Currently there is no effective medical treatment for this common disease, and the impact ofuterinefibroidsonfertilityremainscontroversial.Treatmentoptionsforthemanagementoffibroidshavelargelyfocusedonsurgicaloptions with few focusing on reproductive-sparing procedures. Healthcare providers show no agreement on the best management option, partiallybecauseoftheirlackofcurrentevidence-basedknowledge(includingthecause),ofuterinefibroids.Thislivecourse,designedforgynecologists,willprovideaclearandmeaningfuloverviewoftheproblem,discusscurrentfibroidtreatmentoptionsandtheireffecton fertility, and probe the future of these treatments.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Explainthedevelopmentaloriginofuterinefibroids.2. Describe non-surgical, reproductive-sparing approach for treatment of uterine leiomyomata. 3.SummarizethescientificdataonwhyuterineleiomyomataaremorecommoninAfricanAmericans.4. Discuss the role of myomectomy in the outcomes of assisted reproductive technologies.

CRYOBIOLOGY, CRYOPHYSICS AND QUALITY CONTROL CONCERNS OFGAMETE, EMBRYO AND TISSUE VITRIFICATION


Developed in Cooperation with the Society of Reproductive Biologists and Technologists

FACULTYCharles L. Bormann, Ph.D., ChairMarybeth Gerrity, Ph.D., M.B.A., Co-Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONThepresentationofvitrification(VTF)toinvitrofertilization(IVF)laboratoriesandpracticesisoftenunscientificandchaotic.Themajorityof demonstration and training in VTF techniques has come through workshops sponsored by industry, which are inherently biased toward the media and storage vessels that the company presenting the training has developed. With increasing pressures to conform to human cells, tissue and tissue products (HCT/P) and current good tissue practice (CGTP) standards, set forth by the Food and Drug Administration (FDA), most laboratories are compelled to use devices that are FDA-approved or pending FDA approval. There is great concern surrounding the “technical signature” of using a published VTF method, questioning the simplicity, reliability and repeatability of a given technique. There are growing concerns over the safety of VTF solutions used, cryo-security, and accepting VTF eggs/embryos in unfamiliar VTF devices. We are entering a new era of cryobiology where we are faced with serious quality control challenges. Alternative approaches presented in this live demonstration and hands-on workshop can offer universal uniformity in safety, simplicity, sterility, security and success. To by-pass commercial propaganda and technical signature issues, a hands-on demonstration and workshop of three simple, practical devices currently in use will be used to emphasize the quality control nightmare we will be facing if alternative universal technique(s) are not adopted. Selection of these devices (0.25 mL straw, Hemi straw, and microSecure) for demonstration was based on proven simplicity, low cost, safety and effectiveness of each device without vested commercial interest. This course will provide a solid background in the theories and basic science that has led to the current state of VTF in human systems. We will evaluate the various VTF methods by rating the pros and cons after hands-on experience. We will demonstrate good tissue practices (GTPs) and discuss quality control concerns.

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46TH ANNUAL POSTGRADUATE PROGRAMACGME CompetencyPatient care

LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Participate in the cryobiological/cryophysical principles behind VTF technology via a “hands-on” workshop and contrast VTF to standard slow-freeze preservation.2. Evaluate, demonstrate and practice various non-commercial VTF methods that have been developed and applied, and assess the pros and cons in establishing a VTF program.3.DemonstratelaboratoryGTPsandqualitycontrolconcernsofVTF,andshowhowtheyinfluenceintra-andinter-laboratory success within the methods and devices used in the hands-on workshop.4. Discuss overall quality management in striving to develop a standard global VTF technique (that minimizes “technical signature”) by participating in the use of various VTF techniques.

MODERN MANAGEMENT OF POLYCYSTIC OVARY SYNDROME IN ADOLESCENTSCourse PG17 (Sunday)

Developed in Cooperation with the Pediatric and Adolescent Gynecology Special Interest Group

FACULTYJennifer E. Dietrich, M.S., M.Sc., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONPolycysticovarysyndrome(PCOS)affectsanestimated5-7%ofwomenofreproductiveage.Trueestimatesaredifficult todefineinadolescents, but have been postulated to be higher. Because PCOS is associated with comorbidities such as diabetes mellitus type II, hypertension, non-alcoholic steatosis and obesity as well as other health problems, it is critical to establish an early diagnosis to avoid significanthealthproblemslaterinlife.Thislivecoursedesignedforclinicianswhocareforadolescentfemaleswillcovercurrentscientificpapersandnewareasofresearchthat focus on adolescent needs and screening. Through a lecture/audience participation format, participants will discuss early warning signs such as precocious adrenarche that help providers determine the best time to screen adolescents for PCOS, which should result in improved patient lifelong health.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1.ConfidentlyperformanevaluationforPCOSonanadolescentfemale.2. Differentiate adult criteria from adolescent criteria in making the diagnosis of PCOS.3. Detect early warning signs indicating a possible diagnosis of PCOS in the adolescent and evaluate the need for early screening and early intervention.4. Discuss the available treatment options for adolescents with PCOS.

EARLY LIFE TOXICANT EXPOSURES AND ADULT REPRODUCTIVE DISORDERS:A POTENTIAL ROLE FOR NUTRITIONAL INTERVENTION IN BOTH SEXES


Developed in Cooperation with the Environment and Reproduction Special Interest Group and the Nutrition Special Interest Group

FACULTYKevin G. Osteen, Ph.D., H.C.L.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONFetal programming is a normal component of developmental processes leading to appropriate organ system function in adults. However, early life programming processes can be negatively impacted by various environmental factors, including maternal stress, poor nutrition andexposuretovarioustoxicants.Emergingevidenceimpliesthatdisruptionoffetalandneonatalprogrammingmaysignificantlyaffectan individual’s risk of adult disease, including reproductive failure. This concept, known as Developmental Origins of Health and Disease (DOHaD), requires clinical providers of reproductive medicine to examine the potential role of fetal/neonatal programming on adult pathology affecting fertility. This live course will present experimental evidence and clinical observations linking developmental toxicant exposure to reproductive disorders.Additionally, the faculty will discuss the significance of epigenetic programming on the heritability of toxicant-associateddisordersandwilldescribe the influenceofnutritionon reducing the impactofaprevious toxicantexposure.Finally, thiscoursewillpresent the emerging evidence that environmental toxicant exposure of animals and humans impacts adult reproductive function for multiplegenerationsandwillprovidespecificrecommendationsforproviderstooptimizepatientcareinfertilityclinics.

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46TH ANNUAL POSTGRADUATE PROGRAMACGME CompetencyMedical knowledge

LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Evaluate the evidence implicating environmental toxicant exposure at different stages of life to disruption of adult reproductive tract function and development of disease.2.Listspecifictoxicants,theirroutesofexposureandmechanismsofactionwhichmaynegativelyimpactreproductive processes in humans.3. Describe the DOHaD hypothesis and its relevance to reproductive medicine.4. Discuss how nutrition may modify the negative impact of a prior toxicant exposure and improve reproductive outcomes.5. Develop improved strategies for ascertaining a couple’s exposure history relevant to infertility treatment.

ULTRASOUND IMAGING IN REPRODUCTIVE MEDICINE: A PRACTICAL APPROACHCourse PG19 (Sunday)

Developed in Cooperation with the American Institute of Ultrasound in Medicine and the Imaging in Reproductive Medicine Special Interest Group

FACULTYLaurel A. Stadtmauer, M.D., Ph.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONUltrasound and ultrasound-guided procedures have become integral components, not just of assisted reproductive technology (ART), but also in the day-to-day practice of reproductive medicine, infertility and gynecology. In 2009, new practice guidelines for ultrasound in reproductive medicine were published by the American Institute of Ultrasound in Medicine (AIUM) and in collaboration with the American Society for Reproductive Medicine (ASRM). Surveys of members of the Society for Reproductive Endocrinology and Infertility, the Imaging Special Interest Group and ASRM have revealed a strong desire for CME credits in ultrasonography that would prepare reproductive medicine professionals and gynecologists for accreditation by the AIUM. In addition, there is an interest in training and credentialing reproductivenursesandnursepractitionerstoperformlimitedultrasoundsintheoffice. The objective of this course is to provide comprehensive survey of the use of ultrasonography in the female pelvis for physicians and other healthcare providers who use gynecologic ultrasonography. A practical problem-solving approach will be implemented with case presentations. The faculty will critically review the application of ultrasonography to the infertility evaluation, diagnosis, treatments and complications as a way to maximize ART success. Ultrasound has helped in the early pregnancy evaluation and monitoring as well as inassessingpregnancycomplications.Manyothergynecologicfindingsonultrasoundsuchascongenitaluterineanomalies,ovarianmasses, tubal disease and other uterine pathologies will be discussed along with their impact on fertility and the decision for surgery. A variety of reproductive problems throughout the reproductive lifespan, from puberty through menopause, will be addressed from an ultrasound perspective. Newer technologies with current or potential applications, such as 3-dimensional (3-D) ultrasound, Doppler, and cost-effective use of CT- and MRI-guided procedures will also be covered. There will be interactive discussion of cases and controversies, andparticipantswillalsohave theopportunity to learnpracticalapplicationsandmanipulate3-D images.Thiscoursewill fulfillCMErequirements for AIUM credentialing.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Summarize the appropriate use of ultrasonography in the evaluation of infertility, uterine abnormalities and the pathology of the reproductive tract.2.Describetheproperassessmentofearlypregnancyandlistfindingsonearlypregnancyassessmentsthatareassociated with poor outcome.3.Discusstheimportanceof3-Dultrasonographyinreproductivemedicine,andtheimportanceofDopplerbloodflow assessment in reproductive medicine and gynecology.4. Evaluate patients with pelvic pain, abnormal bleeding and adnexal masses using a practical approach.5. Evaluate when surgical intervention is needed, when cancer is suspected and when imaging procedures can be performed to treat abnormalities on ultrasound.

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GLOBAL FAMILY PLANNING: THE KEY TO ACHIEVING MILLENNIUM DEVELOPMENT GOALSCourse PG20 (Sunday)


Developed in Cooperation with the Contraception Special Interest Group

FACULTYAlison Edelman, M.D., M.P.H., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONUnintended pregnancies continue to be at epidemic levels in the United States and worldwide. Unsafe abortion continues to be one of the top killers of women worldwide. The use of long-acting, reversible and permanent contraceptive methods prevent both pregnancies and abortions. One important barrier to contraceptive use is lack of knowledge and hands-on experience among healthcare providers on “best practices” for contraceptive care. In addition, providers lack the skills for safe abortion care including postabortion and miscarriage management. TheContraceptionSpecialInterestGroupdeterminedthatapostgraduatecoursewithahands-oncomponentwouldbenefitreproductiveendocrinologists, general obstetrician-gynecologists, general internists, family medicine providers, and nurse practitioners. The topics to be covered in this live course include: achieving millennium development goals (MDG) in the current world situation; family planning and the environment; postpartum/postabortion contraception; transcervical and minilaparotomy sterilization; natural family planning; medical management of spontaneous abortions, postabortion care, and safe abortion care; manual vacuum aspiration (MVA) from biopsies, retained placentas, to abortions; resources for the clinician; medical eligibility criteria from the World Health Organization and the Centers for Disease Control; and novel, developing contraception methods. The hands-on component will allow participants to improve clinical skills in postpartum/postabortion intrauterine device (ppIUD) insertion, Essure/Adiana, MVA, transcervical and minilaparotomy permanent contraception, and dilatation and evacuation.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Analyze the current world situation, MDG goals and environmental issues related to population and family planning and recommend resources that aid the clinician in the provision of contraceptive care. 2. Explain family-planning methods with the greatest impact for reducing maternal morbidity and mortality (use of ppIUD, permanent contraception, and novel methods being developed).3. Apply the acquired skills to perform ppIUD insertion and transcervical and minilaparotomy permanent contraception.4. Describe safe and standardized regimens for the medical management of incomplete abortion, miscarriage or undesired pregnancy.5. Describe and demonstrate the use of manual vacuum aspirator for gynecologic, obstetric and family planning indications.

SAFE IN VITRO FERTILIZATIONCourse PG21 (Sunday)

Developed in Cooperation with the Society for Assisted Reproductive Technology

FACULTYValerie L. Baker, M.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONAlthough assisted reproductive technology (ART) is a widely-used treatment that often leads to the birth of healthy children without serious maternal complications, concerns have been raised about increased risk of certain adverse outcomes for both the mother and the offspring. ART has been associated with higher rates of compromised fetal growth, preterm delivery, maternal complications such as preeclampsia, and possibly congenital anomalies and epigenetic disorders. Some risks of adverse outcomes associated with ART are likely attributable to the underlying infertility. However, it is important for clinicians to be aware of ART risks that may be associated with the treatment itself. Some adverse outcomes associated with ART may be attributable to multiple gestation, laboratory practices, or the unphysiologic maternal state in which pregnancy typically begins with ART.ThislivecoursewillequipclinicianstobetterinformpatientsabouttherisksandbenefitsofvariousaspectsofART.Facultywillproviderecommendations on how to mitigate the risks, including optimization of ovulation induction, and maximize the safety of ART. Other topics coveredincludeanup-to-dateunderstandingofthebenefitsandrisksofvariouslaboratoryproceduresandARTtreatmentforpatientswith medical problems.


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46TH ANNUAL POSTGRADUATE PROGRAMLEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Choose individualized ovulation stimulation protocols with consideration given to both potential short-term and long-term consequences for the mother and fetus.2.Explaintherisksandbenefitsoflaboratorypracticessuchasextendedculture,embryobiopsyatdifferentstages,oocytecryopreservationandopenversusclosedvitrification.3. Provide recommendations that will reduce the risk of multiple gestation while still maintaining a high live-birth rate.4. Advise patients at increased risk of pregnancy complications.

THE SIGNIFICANCE, IMPLICATIONS AND HERITABILITY OF MALE INFERTILITY AS A DISEASECourse PG22 (Sunday)

Developed in Cooperation with the Society for Male Reproduction and Urology

FACULTYPaul J. Turek, M.D., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONTheclinicalsignificanceofthemalefactorinfertilityevaluationhasbeenunderestimatedtodate.Giventhewell-describedassociationsbetween male infertility and a) underlying concurrent medical conditions, b) genetic anomalies, c) environmental exposures and d) future cancers,malefactorinfertilityisclearlyadiseaseofclinicalandepidemiologicalsignificance.However,itisestimatedthatlessthanonein four infertile males in the United States receives the recommended male factor evaluation as part of the couple infertility assessment. Educatingcliniciansabouttheimplicationsofmalefactorinfertilityisthefirststepinchangingclinicalbehaviorthatincorporatesthemalefactor evaluation into every couple’s assessment. Through a thorough discussion of our current understanding of the medical, genetic and epidemiologic issues associated with male factor infertility, this course seeks to raise awareness and change practice patterns of clinicians who care for infertile couples. By emphasizing that male infertility is a window into both current and future health of the individual (i.e., is a biomarker of health), this course will: improve clinicians’ level of understanding and knowledge of relevant lifestyle issues and behaviors that are associated with infertility, help clinicians precisely identify those individuals at risk for genetic infertility, and enable clinicians to better educate their patients regarding the health risks associated with a male infertility diagnosis. It is our hope that this course will enlighten clinicians, laboratory technicians and researchers alike of the full impact of male infertility on the health, quality of life and longevity of affected individuals.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Describe three metabolic or hormonal disorders that are associated with male factor infertility.2.ListtheclinicalcriteriathatdefinemenatriskforgeneticinfertilityduetoYchromosomedeletionsorkaryotypeanomalies.3. Delineate four lifestyle, occupational or exposure risk factors linked to male factor infertility.4. List two cancers that are more likely to occur in infertile men than otherwise healthy men AFTER a diagnosis of male factor infertility.5. Explain two genetic or medical conditions in offspring that are associated with severe male factor infertility or older paternal age.

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TRAINING PEOPLE IN LOW-COST INFERTILITY AND ART TREATMENTCourse PG23 (Sunday)

Developed in Cooperation with the International Federation of Fertility Societies

FACULTYIan D. Cooke, M.B., FRCOG, F.Med.Sci., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONAccess to infertility diagnosis and treatment is extremely poor in the developing world. There are too few clinics or private doctors interested in and competent to manage infertility problems, no adequate referral systems, and few trained staff. National health services provide few treatmentsasmanycountriesstrugglewithmajordisease,suchashumanimmunodeficiencyvirus(HIV),malariaandtuberculosis(TB).Available private services are usually too costly for the average patient and can result in catastrophic expense. The most common cause of infertility in developing nations is tubal obstruction from infection, either chlamydia, gonorrhea or postpartum or postabortion sepsis, where the only realistic management plan includes in vitro fertilization (IVF). However, public health education on reproduction is minimal and infertility is surrounded by fear and superstition and compounded by local religious attitudes. Treatment options are not widely known and sophisticated methods, such as assisted reproductive technology (ART), are not available. Management of infertility needs to be conducted within a framework of adequate reproductive health services, so that preparation for pregnancy, the pregnancy and the delivery are competently managed, in places where skilled attendance at delivery may not be standard practice. Health professionals, either nationals of low resource economies or altruistic academics from developed countries, wanting to implement infertility treatments and ART in the developing world must understand the problems and acquire the competence to approach theminwaysthatarecost-effectivefortheirregionandnotsimplyattempttotransfersystemsdevelopedformore-affluentenvironments. This live course will describe how to develop assisted-conception services in low-resource environments. Discussion will cover how tofindsuitablelaboratoryspace,providerobustequipmentandmaintainitinworkingorder,maintainlabrecordswithaviewtoqualitycontrol, trouble shoot, and use the laboratory data to develop the service. Identifying potential patients, patient screening, meeting with both partners, and treatment prior to ART will be emphasized as well as the principles of preparation for pregnancy and obstetric care. The indications for intra-uterine insemination (IUI) and IVF (and the need for intra-cytoplasmic sperm injection [ICSI]) will be elaborated in thecontextofeducationaboutreproductivebiology,pathologyandspecifictreatmentforthecoupleandtheimplicationsforpublichealtheducation. Minimal ovarian stimulation will be discussed in the context of avoiding hyperstimulation and multifetal pregnancy. The critical role of ultrasound will be presented with technical details of appropriate apparatus and the skill requirements and methods for acquiring them will be presented. The role of various staff members will be elaborated and include quality standards.Finally,anappraisalofthefinancialviabilityofdevelopinganassisted-conceptionclinicandtheuseofdataobtainedfromsuchaclinicwillbedetailed.Datacanbereportedtonationalandinternationalregistriesandusedtoattractpatientsandinfluencepolicyrelatedtoservice provision at a national level, thus helping to extend local health service to a greater proportion of the population in accordance withtheWorldHealthOrganizationrubricofappropriately-stratifiedhealthcare.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Explain the rationale for providing assisted-conception services in low-resource environments.2. Develop a clinic offering suitable ART services and competently manage patients in such a setting.3.Specifythestepsrequiredforfinancialviabilityandforqualitydataretentionandreporting.4. Develop educational programs suitable for patients, the general public and health service administrators.

29

46TH ANNUAL POSTGRADUATE PROGRAMPGD IMPACT ON ART EFFICIENCY WITH INTRODUCTION OF

MICROARRAY TECHNOLOGY FOR 24 CHROMOSOME ANEUPLOIDY TESTINGCourse PG24 (Sunday)

Developed in Cooperation with the Preimplantation Genetic Diagnosis Special Interest Group

FACULTYAnver Kuliev, M.D., Ph.D., ChairSantiago Munné, Ph.D., Co-Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONAtleast50%ofoocytesandembryosfrominvitrofertilization(IVF)patientsofadvancedreproductiveagearechromosomallyabnormal,contributingsignificantlytoinfertilityandpregnancyloss.Becauseofthepresentcontroversyontheimpactofpreimplantationgenetictesting (PGT) for aneuploidies on the improvement of assisted reproductive technology (ART), there is a need for the development of efficientandrobustmethodsforpreselectionofaneuploidy-freeembryosfortransfer.Theavailablemethodsbasedonmorphologicalcriteriaarenotsufficientforselectionofembryoswiththehighestdevelopmentalpotential.Thepreviousmethodsforaneuploidytestingwerebasedonthefluorescenceinsituhybridization(FISH)technique,whichhasanimportantlimitationofnotdetectingabnormalitiesofall the chromosomes. In addition, the procedure is predominantly applied at the cleavage stage, which is compromised by the high risk of mosaicism that may contribute to false positive and false negative results. This live course is aimed at increasing the knowledge and competence of fertility specialists and laboratory professionals, but will also be of interest to a wider audience, taking into consideration the recent controversy regarding preimplantation aneuploidy testing. Faculty will introduce microarray technology, which tests for all 24 chromosomes, and the application of this technology to different biopsy materials, including polar bodies, blastomeres and blastocysts. Participants will analyze the different platforms for 24 chromosome aneuploidy testing and review data on the clinical outcome of the application of this methodology.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Evaluate the contribution of the FISH technique to the false positive and false negative results and the impact on the clinical outcome data.2. Describe the practical application of preimplantation 24 chromosome testing to PGD for chromosomal disorders.3. Explain the importance of selection of the optimal biopsy procedure for the highest accuracy of preimplantation 24 chromosome aneuploidy testing.4. Discusstheexpectedefficiencyof24chromosomeaneuploidytesting,dependingonthetypeofmicroarraytechnique used and the differences of the applied biopsy procedures.

MANAGING MENOPAUSE...WITH FINGERS ON THE PULSE AND EYES ON THE FUTURECourse PG25 (Sunday)

Developed in Cooperation with the Menopause Special Interest Group

FACULTYLubna Pal, M.B.B.S., M.S., Chair

NEEDS ASSESSMENT AND COURSE DESCRIPTIONMenopausal management has transformed over the past decade, with an obvious shift from a relatively liberal use of exogenous hormones in the pre-Women’s Health Initiative era, to a more cautious stance regarding the place of menopausal hormone therapy in the management of menopause-related symptoms. Concerns regarding long-term implications of menopausal hormone therapy appear to underlie this change in clinical practice. Although today’s clinicians are sensitized to the unique needs of an individual menopausal woman, and are better aware of the expanding spectrum of therapeutic options, the management paradigms still remain ambiguous for manyandthedichotomyoffindingsfromobservationalstudiesandrandomizedtrialscontinuetoconfusepatientsandprovidersalike.Easyaccessto“proverbial”and“anecdotal”informationviatheInternethasmagnifiedthecomplexityofclinician-patientdiscussionsandfrequentlyinfluencespatientchoicesanddecisionsrelatedtomenopausemanagement.Earlydiagnosisandadvancesinthefieldofoncologyarecontributingtoincreasingnumbersofrelativelyyoungcancersurvivorswhoareexperiencingprematureovarianinsufficiencyafterchemo-radiationtherapy.Clinicalevidencesuggeststhatthehealthburdenattributableto premature cessation of ovarian function in this population may not be adequately appreciated or addressed. It is thus essential for clinicians who care for young female cancer survivors to understand the needs and concerns relating to iatrogenic menopause in this unique population. Today’s targeted approach to clinical practice may restrict a clinician’s ability to explore an individual patient’s non-verbalized concerns, an aspect that is of particular relevance for women transgressing the spectrum of peri and early menopause. In addition to being cognizant of climacteric symptoms and the available strategies for symptom control, providers should also be prepared to treat the needs of perimenopausalandearlymenopausalwomen,includingpreventivecare,riskquantificationandriskreduction,andcontraceptiveandprocreative preferences. The future of menopausal management, driven by concepts of selective estrogen receptor modulators (SERMs), tissueselectiveestrogencomplexes(TSECs)andstemcelltherapy,promisesadynamicterrainthatislikelytoredefinehowwecareforthe perimenopausal and menopausal woman.

30

46TH ANNUAL POSTGRADUATE PROGRAM The decision to offer a particular management strategy is dictated by the patient’s clinical presentation and a thorough evaluation of the individualizedriskversusbenefitprofile.Largegapsexistbetweenpatientexpectationsandprovidercompetencytohelpguidepatientdecision making. Consistent with the literature, surveys conducted by the American Society for Reproductive Medicine (ASRM) in 2009 and2011membersidentifiedpersonalpracticegapsinthetreatmentofmenopause-relatedissues,andrequestededucationalactivitiestospecificallyaddresstheirunderstandingofindividualizedtreatmentapproaches.Thegoalofthislivecourseistoofferacriticalreviewof evidence-based recommendations that will give clinicians the skill set to provide comprehensive, competent care to women making the transition into menopause.


LEARNING OBJECTIVESAt the conclusion of this course, participants should be able to:1. Individualize risk assessment and recommend risk reduction strategies for peri and postmenopausal women, and develop optimal, individualized management strategies of contraceptive and procreative needs in the perimenopausal population.2.Compareandcontrasttheefficacy,safetyandsideeffectsofavailabletherapies(hormonalandnon-hormonal)for common menopausal disorders, and design treatment plans for women with diverse disease states and of different ages with menopausal symptoms and/or osteoporosis. 3. Distinguish the unique needs and risks of women experiencing unnatural menopause (premature, surgical or following chemo-radiation), and develop individualized management strategies.4. Explain emerging concepts in menopausal medicine (e.g., SERMs, TSECs and stem cell).

HYSTEROSCOPYCourse PG26 (Sunday)

Developed in Cooperation with the Society of Reproductive Surgeons

FACULTYSteven F. Palter, M.D., Chair

FUTURE ASRM ANNUAL MEETINGS

October 18-22, 2014Honolulu, HI

Hawaii Convention Center

October 17-21, 2015Baltimore, MD

Baltimore Convention Center

Developed in Cooperation with the American Association of Bioanalysts

FACULTYTammie Schalue, Ph.D., H.C.L.D., E.L.D., Chair

CLINICAL EMBRYOLOGY AND ANDROLOGY FOR PHYSICIANSCourse PG27 (Saturday & Sunday)

Two-Day CourseSaturday, October 12, 2013 - Sunday, October 13, 2013

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IFFS/ASRM 2013 Scientific ProgramNeeds Assessment and Description

Thefieldofreproductivemedicineisevolvingrapidlywithadvancesreflectingthemulticulturalcontributionsoftheglobalcommunityofhealthcareprofessionals.TheIFFSScientificCommitteeandtheASRMScientificProgramCommitteese-lected as their theme for the 2013 conjoint meeting “Transforming Reproductive Medicine Worldwide” to emphasize inter-nationalcollaborativeeffortstoimproveeverypatient’sabilitytofulfillhisorherreproductivedestiny.Reproductivehealth-care is challenged globally by technology, ethics, clinical skill, social customs, religious beliefs, emotions, legal restrictions and cost. Clinicians, scientists and allied health professionals must improve their ability to navigate these uncharted ter-ritoriesinordertoprovideoptimalcarefortheirpatients.Theeducationalactivitiesofthe2013postgraduateandscientificprogramsaredesignedtoenhancethemedicalandscientificknowledge,clinicalandlaboratorycompetenceandprofes-sional performance of the healthcare team in helping patients achieve their goals with regards to reproduction. The program committees have designed postgraduate courses, plenary lectures, symposia, interactive sessions, debates, roundtable discussions and oral and poster free-communication sessions to provide participants with a variety of formats and venues to teach and learn, discuss and debate, and give and receive new information, insight and skill. New to ASRM will be the popular IFFS trilogy format in which three speakers discuss the basic, translational and clinical aspectsofaparticulartopic.Theeducationalandprogramcommitteeshaveidentifiededucationalneedsthroughgapanalyses for education in the areas of male and female infertility, assisted reproductive technology, andrology, endome-triosis, reproductive perturbations by environmental toxicants, sexuality, menopause, contraception, gamete and embryo biology,polycysticovarysyndrome,fibroids,regenerativemedicineandstemcellbiology,andaccesstoreproductivecare in low-resource regions. Experts from around the world will present the most recent cutting-edge evidence regarding diagnosis and treatment of reproductive problems. The 2013 IFFS/ASRM conjoint meeting will provide abundant educational opportunities for reproductive endocrinolo-gists, gynecologists, urologists, family practitioners, internists, embryologists, andrologists, nurses, psychologists, social workers,geneticists,andpracticemanagers.Boththepostgraduateandscientificprogramswillincludementored,hands-on training for those reproductive surgeons wishing to enhance their skills in minimally invasive and robotic surgery. The goalisforeveryprofessionalinthefieldofreproductivemedicineandbiologytoleavethemeetingasabetterpractitionerstimulated to make new discoveries that will advance reproductive healthcare.

Learning Objectives

Attheconclusionofthepostgraduateandscientificprograms,participantsshouldbeableto:

1. Compare and contrast clinical approaches to fertility care in resource-rich and low-resource regions.2. Summarizethelatestscientificadvancesinthebiologyofgameteandembryodevelopment,fibroids,endometrio-

sis, stem cells and polycystic ovary syndrome.3. Discuss optimal methods for producing, culturing, assessing, selecting and cryopreserving human embryos.4. Design evidence-based interventions to treat male reproductive disorders.5. Implement protocols for preimplantation genetic testing to prevent propagation of genetic diseases in assisted

reproductive technologies.6. Counselinfertilepatientsregardingthecosts,bothemotionalandfinancial,ofusingthelatestmedicaltherapies

to build a family.7. Assist postmenopausal women in coping with vasomotor symptoms, bone loss, mood disorders and sleep distur-

bances.8. Recommendthemostappropriatecontraceptivemethodsforpatientsindifferentphysiological,culturalandfinan-

cial circumstances.

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12:00 pm - 5:00 pm • Poster Set-up

5:00 pm - 5:45 pm • Members’ Meetings

6:30 PM • Opening Ceremony and Opening Reception in Exhibit Hall

7:00 am - 12:00 pm • Poster Set-up

7:00 am - 9:00 am IFFS Regional MeetingsJapan Society for Reproductive Medicine (JSRM) - Recent Progress and New Trends of ART in Japan

7:00 am - 9:00 am IFFS Regional MeetingsItalian Society of Fertility - Factors InfluencingEmbryosImplantationandtheirUse in Clinical Practice

7:00 am - 9:00 am IFFS Regional MeetingsTurkish German Gynecological Education and Research Foundation - Implantation Problems in an IVF Patient

7:00 am - 9:00 amHands-on Robotic Surgery Intensive

8:00 am - 9:00 am • Members’ Meetings

9:00 - 9:45 am • Plenary Lecture 1Endowed by a 1987 grant from Ortho Women’s Health

American Society for Reproductive Medicine President’s Guest Lecture Chromosome Ends: Why We Care About Them Elizabeth H. Blackburn, Ph.D. University of California, San Francisco

9:45 am - 10:30 am • Plenary Lecture 2International Federation of Fertility Societies - DeWatteville Lecture To Be Determined

10:30 am - 11:15 amSurgical Instrument Demonstration

10:30 am - 11:15 am • Breaks/Exhibits

11:15 am - 12:45 pmScientific Program Prize Paper Abstract Session 1

11:15 am - 12:45 pmMenopause Day SymposiumFocus on Psychological Well-being in Aging Women Lubna Pal, M.B.B.S., M.Sc. (Chair) Yale University

JoAnn E. Manson, M.D., M.P.H. Harvard School of Public Health

Nanette F. Santoro, M.D. University of Colorado, Denver

Marcelle I. Cedars, M.D. University of California San Francisco Center for Reproductive Health

11:15 am - 12:45 pm • TrilogyEndometriosisGenetics and Epigenetics of Endometriosis Grant Montgomery, M.D. Queensland Institute of Medical Research

Clinical Applications of Stem Cells Hugh S. Taylor, M.D. Yale University

The Management of Pelvic Pain with Infertility Mauricio S. Abrao, M.D. São Paulo University

11:15 am - 12:45 pm • TrilogyFemale Fertility PreservationFundamentals of Cryobiology Claus Yding Andersen, M.Sc., D.M.Sc. University Hospital of Copenhagen

Contemporary Approaches to Ovarian Tissue and Oocyte Cryopreservation To Be Determined

Clinical Application of Fertility Preservation Mitchell P. Rosen, M.D. University of California San Francisco Center for Reproductive Health

11:15 am - 12:45 pm • TrilogyContraceptionMale Contraception Regine L. Sitruk-Ware, M.D. The Population Council

Evaluation of New Approaches to Female Contraception Narendra Malhotra, M.D. Malhotra Hospitals

Global Perspectives on Contraception To Be Determined

11:15 am - 12:45 pm • TrilogyART in the Developing WorldAccess to Reproductive Medicine in the Developing World Willem Ombelet, M.D., Ph.D. University of Genk

Cost Effective Protocol in IVF Korula George, M.D. Bangalore Baptist Hospital

Innovative Laboratory Practice for Developing Countries To Be Determined

11:15 am - 12:45 pm • SymposiumAssociation of Reproductive Managers SymposiumDelivery of Outstanding Service: What We Can Learn from Corporate America Joseph J. Travia, Jr., B.S., M.B.A. (Chair) IntegraMed

11:15 am - 12:45 pm • SymposiumMental Health Professional Group SymposiumChallenges and Controversies in Providing Fertility Preservation to Cancer Patients Elizabeth A. Grill, Psy.D. (Chair) The Center for Reproductive Medicine and Infertility

Melissa B. Brisman, J.D. Surrogate Fund Management, LLC

Glenn L. Schattman, M.D. Weill Medical College of Cornell University

11:15 am - 12:45 pm • SymposiumNurses’ Professional Group Symposium Research and the Nurse Cynthia F. Willson, B.S.N. (Chair) Pacific Fertility

Patricia Herschberger, Ph.D. University of Illinois at Chicago

Monica R. Benson, B.S.N., R.N. Reproductive Medicine Associates of New Jersey

11:15 am - 12:45 pmSociety of Reproductive Surgeons TelesurgeryComplex Endometriosis Surgery

1:00 pm - 2:45 pm • Surgical TutorialInteractive Video: Tubal and Adnexal Surgery To Be Determined

12:45 pm - 2:30 pm • Lunch Break

1:00 pm - 2:00 pmSurgery Day DebatePros and Cons of Robotics in Benign Gynecology Jeffrey M. Goldberg, M.D. (Chair) Cleveland Clinic

1:00 pm - 2:00 pm Interactive SessionMenopause Day Interactive Session Cognitive Issues and Sleep Concerns: Hormones, Aging, or Both? Melissa Wellons, M.D. (Chair) University of Alabama at Birmingham

Pauline Maki, Ph.D. University of Illinois at Chicago

Hadine Joffe, M.D., M.Sc. Harvard Medical School

2013 Scientific Program Daily ScheduleSunday, October 13, 2013

Monday, October 14, 2013

Continued on Next Page...

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2013 Scientific Program Daily Schedule


1:00 pm - 2:00 pm • Interactive SessionEnvironment and Reproduction Special Interest Group Interactive Session Reproductive Health Issues in the Environment Susan H. Benoff, Ph.D. (Chair) North Shore-Long Island Jewish Research Institute

1:00 pm - 2:00 pm • Interactive SessionAndrogen Excess Special Interest Group Interactive SessionHirsutism Treatment Frank Gonzalez, M.D. (Chair) Indiana University School of Medicine

Daniel A. Dumesic, M.D. University of California, Los Angeles

1:00 pm - 2:00 pm • Interactive SessionNurses’ Professional Group and the Mental Health Professional Group Interactive SessionNursing and Mental Health Care for the Infertile Male Dana A. Ohl, M.D. (Chair) University of Michigan

Susanne Quallich, N.P. University of Michigan

William D. Petok, Ph.D. Private Practice, Baltimore

1:00 pm - 2:00 pm • Interactive SessionSociety for Assisted Reproductive Technology Interactive SessionMultiplePregnancies:RisksandBenefits Glenn L. Schattman, M.D. (Chair) Weill Medical College of Cornell University

Eric S. Surrey, M.D. Colorado Center for Reproductive Medicine

1:00 pm - 2:00 pm • Interactive SessionRegenerative Medicine and Stem Cell Biology Special Interest Group Interactive SessionBiology of Male Germ Cell Differentiation Sherman J. Silber, M.D. (Chair) Infertility Center of St. Louis

Ans M. M. van Pelt, Ph.D. University of Amsterdam

Sjoerd Repping, M.D. University of Amsterdam

1:00 pm - 2:00 pm • Interactive SessionSociety for Male Reproduction and Urology Interactive SessionAdvanced Paternal Age: Cause for Concern? Paul J. Turek, M.D. (Chair) Turek Clinic

Rebecca Z. Sokol, M.D., M.P.H. Keck School of Medicine - University of Southern California

1:00 pm - 2:00 pmRoundtable Luncheons

2:30 pm - 3:15 pm • Plenary Lecture 3Endowed by a 1999 grant from Ethicon Endo-Surgery, Inc.

Society of Reproductive Surgeons LectureModern Hysteroscopy Keith B. Isaacson, M.D. Newton Wellesley Hospital

3:15 pm - 4:00 pm • Breaks/Exhibits

3:15 pm - 6:00 pmIFFS General Assembly

4:00 pm – 6:00 pmFree Communication/Oral Abstract Sessions

4:00 pm - 6:00 pmMenopause Day SymposiumAging and Sexuality Sandra A. Carson, M.D. (Chair) Women and Infants Hospital

4:00 pm - 6:00 pm • SymposiumSurgery Day SymposiumCongenital Müllerian Anomalies Samantha M. Pfeifer, M.D. (Chair) University of Pennsylvania

Sara Y. Brucker, M.D. Turbingen University Hospital

Marjan Attaran, M.D. Cleveland Clinic

Assia A. Stepanian, M.D. Center for Women’s Core and Reproductive Surgery

4:00 pm - 6:00 pm • SymposiumUterine Function and Dysfunction Hilary O.D. Critchley, M.D. (Chair) University of Edinburgh

4:00 pm - 6:00 pm • SymposiumLifestyle Factors and Reproductive Health: What Matters? Stacey A. Missmer, D.Sc. (Chair) Harvard Medical School

4:00 pm - 6:00 pm • SymposiumEmpiric Medical Therapy for the Infertile Male: A Critical Assessment Edmund S. Sabanegh, M.D. (Chair) Cleveland Clinic

4:00 pm - 6:00 pm • SymposiumChinese Society of Reproductive Medicine SymposiumFemale Fertility Preservation in China Zi-Jiang Chen, M.D. (Chair) Shandong Provincial Hospital, Shandong University

Xiang Wang Huashan Hospital

Jie Qiao, M.D., Ph.D. Peking University Third Hospital

Zi-Jiang Chen, M.D. Shandong Provincial Hospital, Shandong University

4:00 pm - 6:00 pm • SymposiumEndowed by a 2011 Gift from the Asia-Pacific Biomedical Research Foundation

KY Cha Symposium in Stem Cell Technology and Reproductive Medicine - Uterine Stem Cells Carlos A. Simon, M.D., Ph.D. (Chair) Fundacion IVI, University of Valencia

Erin F. Wolff, M.D. National Institutes of Health

Robert J. Casper, M.D. Toronto Centre for Advanced Reproductive Technology

4:00 pm - 6:00 pm • SymposiumMexican Association of Reproductive Medicine Symposium To Be Determined 5:30 pm - 6:00 pmSociety for Male Reproduction and Urology MinisymposiumHow to Get a Walrus Pregnant: A Proven Recipe Holley Muraco, B.S. Vallejo Six Flags Discovery Kingdom

6:00 pm - 7:00 pm • Members' Meetings

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7:00 am - 9:00 amPoster Abstract Session Continental Breakfast

7:00 am - 9:00 amIFFS Regional MeetingsIndian Society for Assisted Reproduction

7:00 am - 9:00 am IFFS Regional MeetingsPolish Gynaecological Association Section of Fertility and SterilityReproductive Law and Art

9:00 am- 9:45 am • Plenary Lecture 4International Federation of Fertility Societies Jean Cohen Lecture To Be Determined

9:45 am - 10:30 am • Plenary Lecture 5Endowed by a 2011 Gift from Camran Nezhat, M.D.

Camran Nezhat, M.D. LectureSmall RNAs, Stem Cells, and Self-Renewal Haifin Lin, Ph.D. (Chair) Yale Stem Cell Center


11:15 am - 12:45 pm • TrilogyAdhesions and Reproductive SurgeryPathophysiology and Prevention of Adhesions Michael P. Diamond, M.D. Wayne State University

Decision Making in Reproductive Surgery Luk Rombauts, Ph.D. World Endometriosis Research Foundation

New Technologies in Reproductive Surgery To Be Determined

11:15 am - 12:45 pm • TrilogyEndometrial ReceptivityScience of Implantation Jan Brosens, M.D., Ph.D. Imperial College

Trophoblasts and Implantation Christos Coutifaris, M.D., Ph.D. University of Pennsylvania

Hormonal Conditioning of the Endometrium Claire Bourgain, M.D. Vrije Universiteit Brussel

11:15 am - 12:45 pm • TrilogyObesity and ReproductionPathophysiological Effects of Obesity on Reproduction To Be Determined

Reproductive Outcomes After Bariatric Surgery To Be Determined

Weight Management to Improve Outcomes in Infertility To Be Determined

11:15 am - 12:45 pm • TrilogyPremature Ovarian Failure and PerimenopauseGenetic Studies in POF and Early Menopause Joe Leigh Simpson, M.D. March of Dimes

Health Risks in POF and Early Menopause Bart C. Fauser, M.D., Ph.D. University Medical Center, Utrecht

Reproductive Aging and Fertility Therapy Marcelle I. Cedars, M.D. University of California San Francisco Center for Reproductive Health

11:15 am - 12:45 pm • SymposiumContraception Day Special Session IUDs in Nulliparous Women Rebecca H. Allen, M.D. (Chair) Brown University

Katharine O’Connell White, M.D., M.P.H. Tufts University School of Medicine

11:15 am - 12:45 pm • SymposiumAssociation of Reproductive Managers SymposiumThe Integration of Mental Health Professionals in the REI Practice Andrea M. Braverman, Ph.D. (Chair) Braverman Center for Health Journeys

11:15 am - 12:45 pm • SymposiumMental Health Professional Group SymposiumWhat’s Good for the Goose Should Also be Good for the Gander: A Medical and Psychological Discussion of Differences in Donor Oocyte and Donor Sperm Screening, Compensation, and Matching Linda D. Applegarth, Ed.D. (Chair) Weill Medical College of Cornell University

Rene Almeling, Ph.D. Yale University

Alice H. Ruby, M.P.H. The Sperm Bank of California

11:15 am - 12:45 pm • SymposiumNurses’ Professional Group and the Society of Reproductive Biologists and Technologists Joint Symposium A Review of Multi-Cell Embryo and Blastocyst Grading Systems: Stages, Methods, and Timing of their Cryopreservation Carli W. Chapman, M.S. (Chair) The Rinehart Center for Reproductive Medicine

Catherine Racowsky, Ph.D. Brigham and Women’s Hospital ART Center

Barry R. Behr, Ph.D. Stanford Fertility and Reproductive Medicine Center

Holly A. Hughes, B.S.N. Brigham and Women’s Hospital ART Center

11:15 am - 12:45 pmScientific Program Prize Paper Abstract Session 2

11:15 am - 12:45 pm ASRM Video Session 1


1:00 pm - 2:00 pm • Interactive SessionFertility Preservation Special Interest Group Interactive SessionOvarian Stimulation Protocols in the Cancer Population Lynn M. Westphal, M.D. (Chair) Stanford University IVF/ART Program

Nicole L. Noyes, M.D. New York University School of Medicine

1:00 pm - 2:00 pm • Interactive SessionSociety of Reproductive Biologists and Technologists and the Society for Male Reproduction and Urology Interactive SessionMerits of the WHO 5th Edition Semen Analysis Parameters and their Predictive Value for IVF Success. Thomas G. Turner, M.S. (Chair) Texas Fertility Center/Austin IVF

Kristen Ivani, Ph.D. Reproductive Science Center

1:00 pm - 2:00 pm • Interactive SessionPediatric and Adolescent Gynecology Special Interest Group Interactive SessionSexual Abuse of Children/Adolescents Michael J. Heard, M.D. (Chair) Heard Clinic

1:00 pm - 2:00 pm • Interactive SessionChinese Special Interest Group Interactive SessionNatural Cycle and Minimal Stimulation IVF and IVM Ri-Cheng Chian, Ph.D. (Chair) McGill University

Frank D. Yelian, M.D., Ph.D. Life IVF Center



Tuesday, October 15, 2013

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1:00 pm - 2:00 pm • Interactive SessionSociety for Male Reproduction and Urology Interactive SessionPhysiologic Sperm Selection for ICSI: What Is It and Why Do It? Denny Sakkas, Ph.D. (Chair) Yale University IVF Program

Gianpiero Palermo, M.D., Ph.D. Weill Cornell Medical College

Erma Z. Drobnis, Ph.D. University of Missouri-Columbia

1:00 pm - 2:00 pm • Interactive SessionImaging in Reproductive Medicine Special Interest Group Interactive SessionTo Doppler or Not to Doppler for Adnexal Masses Elizabeth E. Puscheck, M.D. (Chair) Wayne State University School Of Medicine

1:00 pm - 2:00 pm • Interactive SessionSociety of Reproductive Surgeons Interactive SessionManagement of Ectopic Pregnancy Togus Tulandi, M.D. (Chair) McGill University

Kurt T. Barnhart, M.D. University of Pennsylvania


2:30 pm - 3:15 pm • Plenary Lecture 6Endowed by a 1992 grant from Wyeth

American Society for Reproductive Medicine/International Federation of Fertility Societies Plenary Joint Lecture Hormone Therapy During Menopause and Its Relation to Breast Cancer and Bone Health Richard J. Santen, M.D. University of Virginia Health System

2:30 pm - 3:15 pmContraception Day Keynote LectureHigh Hopes versus Harsh Realities:The Public-Health Impact of Emergency Contraceptive Pills James Trussell, M.D. Princeton University


4:00 pm - 6:00 pmFree Communication/Oral Abstract Sessions

4:00 pm - 6:00 pm • SymposiumEndometriosis Robert N. Taylor, M.D., Ph.D. (Chair) Emory University

4:00 pm - 6:00 pm • SymposiumPolycystic Ovary Syndrome (PCOS) Richard S. Legro, M.D. (Chair) Pennsylvania State University

4:00 pm - 6:00 pm • SymposiumHealth Policy and ART Alan H. DeCherney, M.D. (Chair) National Institutes of Health

4:00 pm - 6:00 pm • SymposiumAsiaPacificInitiativeonReproductionSymposiumStrategies for Implantation Disorder in ART Bruno Lunenfeld, M.D., Ph.D. (Chair) Prof Emeritus Bar Ilan University, National University of Singapore

Yoshiharu Morimoto, M.D. Center for Reproductive Medicine & Infertility

Robert J. Norman, M.D. University of Adelaide

Andon Hestiantoro, M.D. Division of Reproductive Immunoendocrinology

4:00 pm - 6:00 pm • SymposiumEndowed by 2010 Gifts from EMD Serono, Inc., and the TALOFA Foundation

Howard and Georgeanna Jones Symposium on ARTThe Gamete and Infertility Marco Conti, M.D. (Chair) University of California, San Francisco

4:00 pm - 6:00 pm • SymposiumIndian Society of Assisted Reproduction SymposiumOptimizing ART Results: Step By Step Hrishikesh D. Pai, M.D. (Chair) Lilavati Hospital

Rishma Dhillion Pai, M.D. Lilavati Hospital

Jaideep Malhotra, M. D. Malhotra Hospitals

Nandita P. Palshetkar, M.D. Lilavati Hospital

4:00 pm - 6:00 pm • SymposiumMiddle East Fertility Society Symposium High Dose Gonadotropin Stimulation for IVF: Is it Necessary and Does it have a Negative Effect or Outcome? Suheil J. Muasher, M.D. (Chair) Duke University

Johnny T. Awwad, M.D. American University of Beirut

Fady I. Sharara, M.D. Virginia Center for Reproductive Medicine

5:30 pm - 6:00 pmSociety for Male Reproduction and Urology MinisymposiumCan Sperm Contribute to Poor Embryo Quality? The Role of Sperm RNA Steven Krawetz, Ph.D. Wayne State University


7:00 am - 9:00 am Poster Abstract Session Continental Breakfast

7:00 am - 9:00 am IFFS Regional MeetingsTurkish German Gynecological Education and Research Foundation Endometriosis Related Pain: From Pathophysiology to the New Treatment Options

7:00 am - 9:00 am IFFS Regional MeetingsThe Philippine Society of Reproductive Endocrinology and Infertility (PSREI)REI in the Phillipine Setting

9:00 am - 9:45 am • Plenary Lecture 7American Urological Association Bruce Stewart Memorial Lecture To Be Determined

9:45 am - 10:30 am • Plenary Lecture 8Society for the Study of Reproduction Exchange Lecture To Be Determined


11:15 am - 12:45 pm • TrilogyFibroidsThe Science of Fibroids (Pathobiology of Uterine Fibroids) Erica E. Marsh, M.D. Feinberg School of Medicine, Northwestern University

Natural History of Fibroids Suresh Nair, M.D. Gynecology Consultants Clinic & Surgery

Treatment Options Michal Mara, M.D. Centre for Gynaecological Endoscopy and Minimally Invasive Surgery

11:15 am - 12:45 pm • TrilogyPreimplantation Genetic DiagnosisMeiotic Errors and Polar Body Diagnosis Anver Kuliev, M.D. Reproductive Genetics Institute

Array CGH Dagan Wells, Ph.D. Reprogenetics-UK

Does PGD Improve Live Birth Rates? Luca Gianaroli, M.D. Società Italiana Studi di Medicina della Riproduzione

Wednesday, October 16, 2013

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11:15 am - 12:45 pm • TrilogyMultiple Pregnancy (Evidence-based Practice)Embryo Selection Arne Sunde, M.D. St. Olav’s Hospital

Single-Blastocyst Transfer Osamu Ishihara, M.D., Ph.D. Saitama Medical University

Economics in the Development of Embryo Transfer Policies G. David Adamson, M.D. Fertility Physicians of Northern California

11:15 am - 12:45 pm • TrilogySafety in ARTTowards an Ovarian Hyperstimulation Syndrome-free Clinic Edgar V. Mocanu, M.D. Hari Unit Rotunda Hospital

Laboratory Procedures Confounding Safety Analysis Markus Montag, M.D. University of Bonn

The Outcomes for Children Following Infertility Management Richard Kennedy, M.D. University Hospital

11:15 am - 12:45 pm • SymposiumAssociation of Reproductive Managers SymposiumThe Best Defense is a Strong Offense: Prevention Rita Gruber, B.A. (Chair) Reproductive Medicine Associates of New Jersey

11:15 am - 12:45 pm • SymposiumMental Health Professional Group SymposiumDevelopments in Egg Freezing: Medical, Psychological and Ethical Perspectives Julianne E. Zweifel, Ph.D. (Chair) University of Wisconsin

Lisa Schuman, L.C.S.W. Reproductive Medicine Associates of New York

Alan B. Copperman, M.D. Reproductive Medicine Associates of New York

Andrea M. Braverman, M.D. Braverman Center for Health Journeys

11:15 am - 12:45 pm • SymposiumNurses’ Professional Group Symposium Risk Management for Nurses: Don’t Make it Risky Jeanette Rodriquez, M.S., R.N.C. (Chair) Cornell University

Margaret Swain, R.N., J.D. Private Practice, Baltimore

Sharon G. Edwards, R.N. Boston IVF

11:15 am - 12:45 pmScientific Program Prize Paper Session 3

11:15 am - 12:45 pmASRM Video Session 2


1:00 pm - 2:00 pm • Interactive SessionRegenerative Medicine and Stem Cell Biology Special Interest Group Interactive SessionProperties of Spermatogonial Stem Cells To Be Determined

1:00 pm - 2:00 pm • Interactive SessionNutrition Special Interest Group Interactive SessionInteractive Roles of Nutrition and Medicine and the Importance of Taking Into Account a Patient’s Nutritional Status Prior to Medical Management of Disease Kaylon L. Bruner-Tran, Ph.D. (Chair) Vanderbilt University Medical Center

Dian Shepperson-Mills, M.A. Endometriosis and Fertility Clinic

1:00 pm - 2:00 pm • Interactive SessionSociety of Reproductive Surgeons Interactive SessionTo Be Determined Peter Chan, M.D. (Chair) McGill University

1:00 pm - 2:00 pm • Interactive SessionHealth Disparities Special Interest Group Interactive SessionBiological, Social and Environmental Disparities in Reproduction Gloria Richard-Davis, M.D. (Chair) Meharry Medical College

Ayman Al-Hendy, M.D., Ph.D. Meharry Medical College

Victor Y. Fujimoto, M.D. University of California, San Francisco

1:00 pm - 2:00 pm • Interactive SessionContraception Special Interest Group Interactive SessionHormonal Contraception and Thrombosis Risk: A Debate Michael A. Thomas, M.D. (Chair) Center for Reproductive Health

1:00 pm - 2:00 pm • Interactive SessionNurses’ Professional Group Interactive SessionCurrent Trends with Endometriosis Management Tamara M. Tobias, N.P. (Chair) Seattle Reproductive Medicine

Paul C. Lin, M.D. Seattle Reproductive Medicine


2:30 pm - 3:15 pm • Plenary Lecture 9Endowed by a 1990 grant from TAP Pharmaceutical

Herbert H. Thomas LectureThe Effect of ART and IVF on Epigenetic Programming in the Embryo Renee A. Reijo Pera, Ph.D. Stanford University


3:15 pm - 6:00 pmIFFS General Assembly

4:00 pm - 6:00 pmFree Communication/Oral Abstract Sessions

4:00 pm - 6:00 pm • SymposiumEuropean Society for Human Reproduction and Embryology Symposium To Be Determined

4:00 pm - 6:00 pm • SymposiumLatin American Association for Reproductive Medicine Symposium To Be Determined

4:00 pm - 6:00 pm • SymposiumFertility Preservation Teresa K. Woodruff, Ph.D. (Chair) Northwestern University

Kutluk Oktay, M.D. New York Medical College

Johan E. Smitz, M.D. Laboratory for Hormonology and Clinical Chemistry

4:00 pm - 6:00 pm • SymposiumAssessment of Embryo and Blastocyst Quality Barry R. Behr, Ph.D. (Chair) Stanford Fertility and Reproductive Medicine Center

4:00 pm - 6:00 pm • SymposiumKen Ryan Ethics SymposiumMoving Innovations to Practice To Be Determined

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4:00 pm - 6:00 pm • Symposium Physiology of the Oocyte and Embryo: From Reproductive Biology to Reproductive MedicineA Celebration of Professor John D. Biggers Catherine Racowsky, Ph.D. (Chair) Brigham and Women’s Hospital ART Center

John Eppig, Ph.D. Jackson Laboratory

David Whittingham, Ph.D. St. George’s, University of London

Ginny Papaioannou, Ph.D. Columbia University

Jay Baltz, Ph.D. Ottawa Hospital Research Institute

5:30 pm - 6:00 pmSociety for Male Reproduction and Urology MinisymposiumWhere Are We With Germ Line (Sperm and Eggs) Stem Cells? Amander Clark, Ph.D. University of California, Los Angeles


7:00 pm - 11:00 pm • IFFS/ASRM GalaMuseum Night at the Museum of Science

7:00 am - 9:00 amPoster Abstract Session Continental Breakfast

7:00 am - 9:00 am IFFS Regional MeetingsAsociación LatinoAmericana de Medicina Reproductive (ALMER) and Sociedad Argentina de Medicina Reproductiva (SAMeR)Men and ART, What is New?

7:00 am - 9:00 am IFFS Regional MeetingsArab Associations of OBGYN Societies Pan Arab Fertility Meeting

9:00 am - 9:45 am • Plenary Lecture 10Endowed by a 1990 grant from Astra-Zeneca

Stem Cells in Endometrium and Endometriosis Hugh S. Taylor, M.D. Yale University School of Medicine

9:45 am - 10:30 amASRM Members’ Meeting


11:15 am - 12:45 pm • TrilogyToxicants and ReproductionThe Testis Jorma Toppari, M.D., Ph.D. University of Turku

The Ovary Robert F. Casper, M.D. Toronto Centre for Advanced Reproductive Technology

Toxicants in Pregnancy and Neonatal Outcome Tracey Woodruff, M.D., M.P.H. University of California, San Francisco

11:15 am - 12:45 pm • TrilogyContemporary Approaches to PCOS Management (PCOS Update)Genetics of PCOS Zi-Jiang Chen, M.D. Shandong Provincial Hospital, Shandong University

Global Differences in Presentation of PCOS Fahrettin Kelestimur, M.D. Erciyes University Medical School

Management of PCOS Basil C. Tarlatzis, M.D., Ph.D. University of Thessaloniki

11:15 am - 12:45 pm • TrilogyOptimizing ART Outcomes / Evidence-based MedicineChasing the Holy Grail of Pregnancy Rates - at the Expense of Safety? Paul Devroey, M.D., Ph.D. UZ Brussel

Systemic Reviews: Building Blocks for the Best Practice of ART Cynthia Farquhar, M.D., M.P.H. Auckland Gynaecology Group

Translating Evidence into Practice Sudhindra M. Bhattacharya, M.B.B.S. KPC Medical College

11:15 am - 12:45 pm • IFFS Surveillance

11:15 am - 12:45 pmAAGL Film Festival Video Session

12:45 pm - 1:00 pm • Break

1:00 pm - 1:45 pm • Plenary Lecture 11Endowed by a 1992 grant from EMD Serono, Inc.

Mechanisms of Energy Expenditure in Embryos Kelle H. Moley, M.D. Washington University

1:45 pm - 2:30 pmSummary of MeetingAwards/Closing Ceremony

2013 Scientific Program Daily ScheduleThursday, October 17, 2013

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MENOPAUSE DAY MONDAY, OCTOBER 14, 2013

11:15 am - 12:45 pmMenopause Day Symposium - Focus on Psychological Well-being in Aging Women

Lubna Pal, M.B.B.S., M.Sc. (Chair) Yale University



Marcelle I. Cedars, M.D. University of California San Francisco Center for Reproductive Health

1:00 pm - 2:00 pmMenopause Day Interactive Session - Cognitive Issues and Sleep Concerns:

Hormones, Aging, or Both?Melissa Wellons, M.D. (Chair)

University of Alabama at BirminghamPauline Maki, Ph.D.

University of Illinois at ChicagoHadine Joffe, M.D., M.Sc. Harvard Medical School

4:00 pm - 6:00 pmMenopause Day Symposium - Aging and Sexuality

Sandra A. Carson, M.D. (Chair) Women and Infants Hospital

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SURGERY DAY MONDAY, OCTOBER 14, 2013

7:00 am - 9:00 amHands-on Robotic Surgery Intensive

11:15 am - 12:45 pmSociety of Reproductive Surgeons Telesurgery

Complex Endometriosis Surgery

1:00 pm - 2:45 pmSurgical Tutorial

Interactive Video: Tubal and Adnexal Surgery

1:00 pm - 2:00 pmSurgery Day Debate

Pros and Cons of Robotics in Benign GynecologyJeffrey M. Goldberg, M.D. (Chair)

Cleveland Clinic

2:30 pm - 3:15 pmPlenary Lecture 3

Society of Reproductive Surgeons Lecture - Modern HysteroscopyKeith B. Isaacson, M.D.

Newton Wellesley Hospital

4:00 pm - 6:00 pmSymposium

Surgery Day Symposium - Congenital Müllerian AnomaliesSamantha M. Pfeifer, M.D. (Chair)

University of PennsylvaniaSara Y. Brucker, M.D.

Turbingen University HospitalMarjan Attaran, M.D.

Cleveland ClinicAssia A. Stepanian, M.D.

Center for Women’s Core and Reproductive Surgery

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CONTRACEPTION DAY TUESDAY, OCTOBER 15, 2013

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11:15 am - 12:45 pm • SymposiumContraception Day Special Session

IUDs in Nulliparous WomenRebecca H. Allen, M.D. (Chair)

Brown UniversityKatharine O’Connell White, M.D., M.P.H.

Tufts University School of Medicine

2:30 pm - 3:15 pm • Contraception Day Keynote LectureHigh Hopes versus Harsh Realities:

The Public-Health Impact of Emergency Contraceptive PillsJames Trussell, M.D.Princeton University

Check in at www.asrm.orgfor upcoming

2013Spouse/Guest Program

Announcements!

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Plenary Sessions

9:00 - 9:45 am • Plenary Lecture 1Endowed by a 1987 grant from Ortho Women’s Health

American Society for Reproductive Medicine President’s Guest LectureChromosome Ends: Why We Care About Them

Elizabeth H. Blackburn, Ph.D.University of California, San Francisco

9:45 am - 10:30 am • Plenary Lecture 2International Federation of Fertility Societies

DeWatteville LectureTo Be Determined

2:30 pm - 3:15 pm • Plenary Lecture 3Endowed by a 1999 grant from Ethicon Endo-Surgery, Inc.

Society of Reproductive Surgeons LectureModern HysteroscopyKeith B. Isaacson, M.D.

Newton Wellesley Hospital

9:00 am- 9:45 am • Plenary Lecture 4International Federation of Fertility Societies

Jean Cohen LectureTo Be Determined

9:45 am - 10:30 am • Plenary Lecture 5Endowed by a 2011 Gift from Camran Nezhat, M.D.

Camran Nezhat, M.D., LectureSmall RNAs, Stem Cells, and Self-Renewal

HaifinLin,Ph.D.(Chair) Yale Stem Cell Center

2:30 pm - 3:15 pm • Plenary Lecture 6Endowed by a 1992 grant from Wyeth

American Society for Reproductive Medicine/International Federation of Fertility Societies Joint Plenary Lecture

Hormone Therapy During Menopause and Its Relation to Breast Cancer and Bone HealthRichard J. Santen, M.D.

University of Virginia Health System



43


Plenary Sessions

9:00 am - 9:45 am • Plenary Lecture 7American Urological Association Bruce Stewart Memorial Lecture

To Be Determined

9:45 am - 10:30 am • Plenary Lecture 8Society for the Study of Reproduction Exchange Lecture

To Be Determined

2:30 pm - 3:15 pm • Plenary Lecture 9Endowed by a 1990 grant from TAP Pharmaceutical

Herbert H. Thomas LectureThe Effect of ART and IVF on Epigenetic Programming in the Embryo

Renee A. Reijo Pera, Ph.D.Stanford University

Thursday, October 17, 2013

9:00 am - 9:45 am • Plenary Lecture 10Endowed by a 1990 grant from Astra-Zeneca

Stem Cells in Endometrium and EndometriosisHugh S. Taylor, M.D.

Yale University School of Medicine

1:00 pm - 1:45 pm • Plenary Lecture 11Endowed by a 1992 grant from EMD Serono, Inc.

Mechanisms of Energy Expenditure in EmbryosKelle H. Moley, M.D.

Washington University

44

Trilogies

Endometriosis11:15 am - 12:45 pm

Genetics and Epigenetics of EndometriosisGrant Montgomery, M.D.

Queensland Institute of Medical Research

Clinical Applications of Stem CellsHugh S. Taylor, M.D.

Yale University

The Management of Pelvic Pain with InfertilityMauricio S. Abrao, M.D. São Paulo University

Female Fertility Preservation11:15 am - 12:45 pm

Fundamentals of CryobiologyClaus Yding Andersen, M.Sc., D.M.Sc.

University Hospital of Copenhagen

Contemporary Approaches to Ovarian Tissue and Oocyte CryopreservationJacques G. Donnez, M.D.

Université Catholique de Lourain

Clinical Application of Fertility PreservationMitchell P. Rosen, M.D.

University of California San Francisco Center for Reproductive Health

Contraception11:15 am - 12:45 pm

Male ContraceptionRegine L. Sitruk-Ware, M.D.

The Population Council

Evaluation of New Approaches to Female ContraceptionNarendra Malhotra, M.D.

Malhotra Hospitals

Global Perspectives on ContraceptionTo Be Determined


45

Trilogies

ART in the Developing World11:15 am - 12:45 pm

Access to Reproductive Medicine in the Developing WorldWillem Ombelet, M.D., Ph.D.

University of Genk

Cost Effective Protocol in IVFKorula George, M.D.

Bangalore Baptist Hospital

Innovative Laboratory Practice for Developing CountriesTo Be Determined

Adhesions and Reproductive Surgery11:15 am - 12:45 pm

Pathophysiology and Prevention of AdhesionsMichael P. Diamond, M.D.Wayne State University

Decision Making in Reproductive SurgeryLuk Rombauts, Ph.D.

World Endometriosis Research Foundation

New Technologies in Reproductive SurgeryTo Be Determined

Endometrial Receptivity11:15 am - 12:45 pm

Science of ImplantationJan Brosens, M.D., Ph.D.

Imperial College

Trophoblasts and ImplantationChristos Coutifaris, M.D., Ph.D.

University of Pennsylvania

Hormonal Conditioning of the EndometriumClaire Bourgain, M.D.

Vrije Universiteit Brussel



46

Trilogies

Obesity and Reproduction11:15 am - 12:45 pm

Pathophysiological Effects of Obesity on ReproductionTo Be Determined

Reproductive Outcomes After Bariatric SurgeryTo Be Determined

Weight Management to Improve Outcomes in InfertilityLisa Moran, Ph.D.

University of Adelaide

Premature Ovarian Failure and Perimenopause11:15 am - 12:45 pm

Genetic Studies in POF and Early MenopauseJoe Leigh Simpson, M.D.

March of Dimes

Health Risks in POF and Early MenopauseBart C. Fauser, M.D., Ph.D.

University Medical Center, Utrecht

Reproductive Aging and Fertility TherapyMarcelle I. Cedars, M.D.

University of California San Francisco Center for Reproductive Health


47

Trilogies

Fibroids11:15 am - 12:45 pm

The Science of Fibroids (Pathobiology of Uterine Fibroids)Erica E. Marsh, M.D.

Feinberg School of Medicine, Northwestern University

Natural History of FibroidsSuresh Nair, M.D.

Gynecology Consultants Clinic & Surgery

Treatment OptionsMichal Mara, M.D.

Centre for Gynaecological Endoscopy and Minimally Invasive Surgery

Preimplantation Genetic Diagnosis11:15 am - 12:45 pm

Meiotic Errors and Polar Body DiagnosisAnver Kuliev, M.D.

Reproductive Genetics Institute

Array CGHDagan Wells, Ph.D. Reprogenetics-UK

Does PGD Improve Live Birth Rates?Luca Gianaroli, M.D.

Società Italiana Studi di Medicina della Riproduzione

Multiple Pregnancy (Evidence-based Practice)11:15 am - 12:45 pm

Embryo SelectionArne Sunde, M.D.St. Olav’s Hospital

Single-Blastocyst TransferOsamu Ishihara, M.D., Ph.D. Saitama Medical University

Economics in the Development of Embryo Transfer PoliciesG. David Adamson, M.D.

Fertility Physicians of Northern California


48

Trilogies

Safety in ART11:15 am - 12:45 pm

Towards an Ovarian Hyperstimulation Syndrome-free ClinicEdgar V. Mocanu, M.D.

Hari Unit Rotunda Hospital

Laboratory Procedures Confounding Safety AnalysisMarkus Montag, M.D.

University of Bonn

The Outcomes for Children Following Infertility ManagementRichard Kennedy, M.D.

University Hospital

Toxicants and Reproduction11:15 am - 12:45 pm

The TestisJorma Toppari, M.D., Ph.D.

University of Turku

The OvaryRobert F. Casper, M.D.

Toronto Centre for Advanced Reproductive Technology

Toxicants in Pregnancy and Neonatal OutcomeTracey Woodruff, M.D., M.P.H.

University of California, San Francisco

Contemporary Approaches to PCOS Management (PCOS Update)11:15 am - 12:45 pm

Genetics of PCOSZi-Jiang Chen, M.D.

Shandong Provincial Hospital, Shandong University

Global Differences in Presentation of PCOSFahrettin Kelestimur, M.D.

Erciyes University Medical School

Management of PCOSBasil C. Tarlatzis, M.D., Ph.D.

University of Thessaloniki



49

Trilogies

Optimizing ART Outcomes / Evidence-based Medicine11:15 am - 12:45 pm

Chasing the Holy Grail of Pregnancy Rates - at the Expense of Safety?Paul Devroey, M.D., Ph.D.

UZ Brussel

Systemic Reviews: Building Blocks for the Best Practice of ARTCynthia Farquhar, M.D., M.P.H. Auckland Gynaecology Group

Translating Evidence into PracticeSudhindra M. Bhattacharya, M.B.B.S.

KPC Medical College


50

ASRM Morning SymposiaMonday

October 14, 2013Tuesday

October 15, 2013

11:15 am - 12:45 pmContraception Day Special Session

IUDs in Nulliparous WomenRebecca H. Allen, M.D. (Chair)

Brown University

Katharine O’Connell White, M.D., M.P.H.

Tufts University School of Medicine

11:15 am - 12:45 pmAssociation of Reproductive

Managers SymposiumThe Integration of Mental Health Professionals in the REI PracticeAndrea M. Braverman, Ph.D. (Chair)

Braverman Center for Health Journeys

11:15 am - 12:45 pmMental Health Professional Group

SymposiumWhat’s Good for the Goose Should

Also be Good for the Gander: A Medical and Psychological Discussion of Differences in

Donor Oocyte and Donor Sperm Screening, Compensation, and

MatchingLinda D. Applegarth, Ed.D. (Chair) Weill Medical College of Cornell University

Rene Almeling, Ph.D.Yale University

Alice H. Ruby, M.P.H. The Sperm Bank of California

11:15 am - 12:45 pmNurses’ Professional Group and

the Society of Reproductive Biologists and Technologists Joint Symposium A Review of Multi-Cell Embryo and Blastocyst Grading Systems: Stages, Methods, and Timing of their Cryopreservation

Carli W. Chapman, M.S. (Chair) The Rinehart Center for Reproductive Medicine

Catherine Racowsky, Ph.D.Brigham and Women’s Hospital ART Center

Barry R. Behr, Ph.D. (Chair) Stanford Fertility and Reproductive Medicine

Center

Holly A. Hughes, B.S.N. Brigham and Women’s Hospital ART Center

11:15 am - 12:45 pmMenopause Day Symposium

Focus on Psychological Well-being in Aging Women

Lubna Pal, M.B.B.S., M.Sc. (Chair) Yale University



Marcelle I. Cedars, M.D. University of California

San Francisco Center for Reproductive Health


Managers SymposiumDelivery of Outstanding Service:

What We Can Learn fromCorporate America

Joseph J. Travia, Jr., B.S., M.B.A. (Chair)

IntegraMed

11:15 am - 12:45 pmMental Health Professional

Group SymposiumChallenges and Controversies in Providing Fertility Preservation to

Cancer PatientsElizabeth A. Grill, Psy.D. (Chair)

The Center for Reproductive Medicine and Infertility

Melissa B. Brisman, J.D.Surrogate Fund Management, LLC

Glenn L. Schattman, M.D. Weill Medical College of

Cornell University

11:15 am - 12:45 pmNurses’ Professional Group

SymposiumResearch and the Nurse

Cynthia F. Willson, B.S.N. (Chair) Pacific Fertility

Patricia Herschberger, Ph.D.University of Illinois at Chicago

Monica R. Benson, B.S.N., R.N. Reproductive Medicine Associates of

New Jersey


Managers SymposiumThe Best Defense is a Strong

Offense: PreventionRita Gruber, B.A. (Chair)

Reproductive Medicine Associates of New Jersey

11:15 am - 12:45 pmMental Health Professional Group

SymposiumDevelopments in Egg Freezing:

Medical, Psychological and Ethical Perspectives

Julianne E. Zweifel, Ph.D. (Chair) University of Wisconsin

Lisa Schuman, L.C.S.W.Reproductive Medicine Associates of

New York

Alan B. Copperman, M.D.Reproductive Medicine Associates of

New York

Andrea M. Braverman, M.D.Braverman Center for Health Journeys

11:15 am - 12:45 pmNurses’ Professional Group

SymposiumRisk Management for Nurses:

Don’t Make it RiskyJeanette Rodriquez, M.S., R.N.C.

(Chair) Cornell University

Margaret Swain, R.N., J.D.Private Practice, Baltimore

Sharon G. Edwards, R.N. Boston IVF

Wednesday,October 16, 2013

51

ASRM Afternoon Symposia

4:00 pm - 6:00 pmMenopause Day Symposium

Aging and SexualitySandra A. Carson, M.D. (Chair)

Women and Infants Hospital

4:00 pm - 6:00 pmSurgery Day Symposium

Congenital Müllerian AnomaliesSamantha M. Pfeifer, M.D. (Chair)

University of Pennsylvania

Sara Y. Brucker, M.D.Turbingen University Hospital

Marjan Attaran, M.D. Cleveland Clinic

Assia A. Stepanian, M.D.Center for Women’s Core and

Reproductive Surgery

4:00 pm - 6:00 pmUterine Function and DysfunctionHilary O.D. Critchley, M.D. (Chair)

University of Edinburgh

4:00 pm - 6:00 pmLifestyle Factors and Reproductive

Health: What Matters?Stacey A. Missmer, D.Sc. (Chair)

Harvard Medical School

4:00 pm - 6:00 pmEmpiric Medical Therapy for the

Infertile Male: A Critical AssessmentEdmund S. Sabanegh, M.D. (Chair)

Cleveland Clinic

4:00 pm - 6:00 pmChinese Society of Reproductive

Medicine SymposiumFemale Fertility Preservation

in ChinaZi-Jiang Chen, M.D. (Chair)

Shandong Provincial Hospital, Shandong University

Xiang WangHuashan Hospital

Jie Qiao, M.D., Ph.D. Peking University Third Hospital

4:00 pm - 6:00 pmSymposium

EndometriosisRobert N. Taylor, M.D., Ph.D. (Chair)

Emory University

4:00 pm - 6:00 pmPolycystic Ovary Syndrome (PCOS)

Richard S. Legro, M.D. (Chair) Pennsylvania State University

4:00 pm - 6:00 pmHealth Policy and ART

Alan H. DeCherney, M.D. (Chair) National Institutes of Health

4:00 pm - 6:00 pmAsia Pacific Initiative on

Reproduction Symposium Strategies for Implantation

Disorder in ARTBruno Lunenfeld, M.D., Ph.D. (Chair)

Prof Emeritus Bar Ilan University, National University of Singapore

Yoshiharu Morimoto, M.D.Center for Reproductive Medicine

& Infertility

Robert J. Norman, M.D. University of Adelaide

Andon Hestiantoro, M.D. Division of Reproductive Immunoendocrinology

4:00 pm - 6:00 pmEndowed by 2010 Gifts from EMD Serono, Inc.,

and the TALOFA Foundation

Howard and Georgeanna Jones Symposium on ART

The Gamete and InfertilityMarco Conti, M.D. (Chair)


4:00 pm - 6:00 pmIndian Society of Assisted Reproduction Symposium

Optimizing ART Results: Step By Step

Hrishikesh D. Pai, M.D. (Chair) Lilavati Hospital

Rishma Dhillion Pai, M.D.Lilavati Hospital

Jaideep Malhotra, M. D. Malhotra Hospitals

MondayOctober 14, 2013

TuesdayOctober 15, 2013

4:00 pm - 6:00 pmEndowed by a 2011 Gift from the Asia-Pacific

Biomedical Research Foundation

KY Cha Symposium in Stem Cell Technology and Reproductive

MedicineUterine Stem Cells

Carlos A. Simon, M.D., Ph.D. (Chair) Fundacion IVI, University of Valencia

Erin F. Wolff, M.D.National Institutes of Health

Robert J. Casper, M.D. Toronto Centre for Advanced Reproductive

Technology

4:00 pm - 6:00 pmMexican Association of

Reproductive Medicine SymposiumTo Be Determined


52

4:00 pm - 6:00 pmMiddle East Fertility Society

SymposiumHigh Dose Gonadotropin

Stimulation for IVF: Is it Necessary and Does it have a Negative Effect

or Outcome?Suheil J. Muasher, M.D. (Chair)

Duke University

Johnny T. Awwad, M.D.American University of Beirut

Fady I. Sharara, M.D.Virginia Center for Reproductive Medicine

ASRM Afternoon Symposia

4:00 pm - 6:00 pmEuropean Society for Human

Reproduction and Embryology Symposium

To Be Determined

4:00 pm - 6:00 pmLatin American Association for

Reproductive Medicine Symposium To Be Determined

4:00 pm - 6:00 pmFertility Preservation

Teresa K. Woodruff, Ph.D. (Chair) Northwestern University

Johan E. Smitz, M.D.Laboratory for Hormonology and Clinical

Chemistry

4:00 pm - 6:00 pmAssessment of Embryo and

Blastocyst QualityBarry R. Behr, Ph.D. (Chair)

Stanford Fertility and Reproductive Medicine Center

4:00 pm - 6:00 pmKen Ryan Ethics Symposium

Moving Innovations to PracticeTo Be Determined

4:00 pm - 6:00 pmPhysiology of the Oocyte and Embryo: From Reproductive

Biology to Reproductive MedicineA Celebration of

Professor John D. BiggersCatherine Racowsky, Ph.D. (Chair)Brigham and Women’s Hospital ART Center

John Eppig, Ph.D.Jackson Laboratory

David Whittingham, Ph.D.St. George’s, University of London

Ginny Papaioannou, Ph.D.Columbia University

Jay Baltz, Ph.D.Ottawa Hospital Research Institute

WednesdayOctober 16, 2013

53

Interactive Sessions

Menopause Day Interactive SessionCognitive Issues and Sleep Concerns: Hormones, Aging, or Both?

Melissa Wellons, M.D. (Chair) University of Alabama at Birmingham

Pauline Maki, Ph.D. University of Illinois at Chicago

Hadine Joffe, M.D., M.Sc. Harvard Medical School

Environment and Reproduction Special Interest Group Interactive SessionReproductive Health Issues in the Environment

Susan H. Benoff, Ph.D. (Chair) North Shore-Long Island Jewish Research Institute

Androgen Excess Special Interest Group Interactive SessionHirsutism Treatment

Frank Gonzalez, M.D. (Chair) Indiana University School of Medicine

Daniel A. Dumesic, M.D.University of California, Los Angeles

Nurses’ Professional Group and the Mental Health Professional Group Interactive SessionNursing and Mental Health Care for the Infertile Male

Dana A. Ohl, M.D. (Chair) University of MichiganSusanne Quallich, N.P.University of Michigan

William D. Petok, Ph.D. Private Practice, Baltimore

Society for Assisted Reproductive Technology Interactive SessionMultiple Pregnancies: Risks and Benefits

Glenn L. Schattman, M.D. (Chair) Weill Medical College of Cornell University

Eric S. Surrey, M.D.Colorado Center for Reproductive Medicine

Regenerative Medicine and Stem Cell Biology Special Interest Group Interactive SessionBiology of Male Germ Cell Differentiation

Sherman J. Silber, M.D. (Chair) Infertility Center of St. LouisAns M. M. van Pelt, Ph.D.University of Amsterdam

Sjoerd Repping, M.D. University of Amsterdam

Monday, October 14, 2013 g 1:00 pm - 2:00 pm

54

Fertility Preservation Special Interest Group Interactive SessionOvarian Stimulation Protocols in the Cancer Population

Lynn M. Westphal, M.D. (Chair) Stanford University IVF/ART Program

Nicole L. Noyes, M.D.New York University School of Medicine

Society of Reproductive Biologists and Technologists andthe Society for Male Reproduction and Urology Interactive Session

Merits of the WHO 5th Edition Semen Analysis Parametersand their Predictive Value for IVF Success.

Thomas G. Turner, M.S. (Chair) Texas Fertility Center/Austin IVF

Kristen Ivani, Ph.D.Reproductive Science Center

Pediatric and Adolescent Gynecology Special Interest Group Interactive SessionSexual Abuse of Children/Adolescents

Michael J. Heard, M.D. (Chair) Heard Clinic

Chinese Special Interest Group Interactive SessionNatural Cycle and Minimal Stimulation IVF and IVM

Ri-Cheng Chian, Ph.D. (Chair) McGill University

Frank D. Yelian, M.D., Ph.D.Life IVF Center

Society for Male Reproduction and Urology Interactive SessionPhysiologic Sperm Selection for ICSI: What Is It and Why Do It?

Denny Sakkas, Ph.D. (Chair) Yale University IVF Program

Gianpiero Palermo, M.D., Ph.D.Weill Cornell Medical College

Erma Z. Drobnis, Ph.D. University of Missouri-Columbia


Society for Male Reproduction and Urology Interactive SessionAdvanced Paternal Age: Cause for Concern?

Paul J. Turek, M.D. (Chair) Turek Clinic

Rebecca Z. Sokol, M.D., M.P.H.Keck School of Medicine - University of Southern California

Monday, October 14, 2013 g 1:00 pm - 2:00 pm

Tuesday, October 15, 2013 g 1:00 pm - 2:00 pm

55

Regenerative Medicine and Stem Cell Biology Special Interest Group Interactive SessionProperties of Spermatogonial Stem Cells

To Be Determined

Nutrition Special Interest Group Interactive SessionInteractive Roles of Nutrition and Medicine and the Importance of Taking

Into Account a Patient’s Nutritional Status Prior to Medical Management of DiseaseKaylon L. Bruner-Tran, Ph.D. (Chair) Vanderbilt University Medical Center

Dian Shepperson-Mills, M.A.Endometriosis and Fertility Clinic

Society of Reproductive Surgeons Interactive SessionTo Be Determined

Peter Chan, M.D. (Chair) McGill University

Health Disparities Special Interest Group Interactive SessionBiological, Social and Environmental Disparities in Reproduction

Gloria Richard-Davis, M.D. (Chair) Meharry Medical College

Ayman Al-Hendy, M.D., Ph.D.Meharry Medical CollegeVictor Y. Fujimoto, M.D.


Contraception Special Interest Group Interactive SessionHormonal Contraception and Thrombosis Risk: A Debate

Michael A. Thomas, M.D. (Chair) University of Cincinnati


Imaging in Reproductive Medicine Special Interest Group Interactive SessionTo Doppler or Not to Doppler for Adnexal Masses

Elizabeth E. Puscheck, M.D. (Chair) Wayne State University School Of Medicine

Society of Reproductive Surgeons Interactive SessionManagement of Ectopic Pregnancy

Togus Tulandi, M.D. (Chair) McGill University

Kurt T. Barnhart, M.D.University of Pennsylvania

Tuesday, October 15, 2013 g 1:00 pm - 2:00 pm

Wednesday, October 16, 2013 g 1:00 pm - 2:00 pm

56


Nurses’ Professional Group Interactive SessionCurrent Trends with Endometriosis Management

Tamara M. Tobias, N.P. (Chair) Seattle Reproductive Medicine

Paul C. Lin, M.D.Seattle Reproductive Medicine

Wednesday, October 16, 2013 g 1:00 pm - 2:00 pm

SOCIETY FOR MALE REPRODUCTION AND UROLOGYMINISYMPOSIA

Monday, October 14, 20135:30 pm - 6:00 pm

How to Get a Walrus Pregnant: A Proven Recipe

Holley Muraco, B.S.Vallejo Six Flags Discovery Kingdom

Tuesday, October 15, 20135:30 pm - 6:00 pm

Can Sperm Contribute to Poor Embryo Quality?

The Role of Sperm RNASteven Krawetz, Ph.D.Wayne State University

Wednesday, October 16, 20135:30 pm - 6:00 pm

Where Are We With Germ Line (Sperm and Eggs) Stem

Cells?Amander Clark, Ph.D.

University of California, Los Angeles

VIDEO SESSIONSTuesday, October 15, 2013

11:15 am - 12:45 pmASRM Video Session 1

Wednesday, October 16, 201311:15 am - 12:45 pm

ASRM Video Session 2

Thursday, October 17, 201311:15 am - 12:45 pm

AAGL Film Festival Video Session

SAVE THE DATES & JOIN US!A joint meeting of the

European Society of HumanReproduction and Embryology

and the American Society for Reproductive Medicine

March 6-10, 2013Atlantis, Paradise Island, Bahamas

Registration and program details availablein July 2012 at www.asrm.org

THE BEST OF ESHRE & ASRM

News and Education

• Access to cutting-edge research in the Society’s peer-reviewed journals, Fertilityand Sterility and the Journal of Assisted Reproduction and Genetics

• Electronic bulletins from our Washington D.C. offi ce that help you stay up to date on the latest reproductive health policy news

• Access to printable Practice Guidelines and Ethics Statements

Professional Development and Recognition

• Opportunities for continuing medical education in-person and online

• Input into shaping policies and protocols through Affi liated Societies, Special Interest Groups, and Professional Groups

• Networking opportunities including online listservs and small group meetings

• Eligibility to receive ASRM research grants and awards

Specials and Discounts

• Savings of at least $200 at the ASRM Annual Meeting

• Discounts on CME, CE, and PEER credits through ASRM eLearn™

• Promotional rates on products and services for ASRM members only

Online Resources for Members Only

• A one-stop ASRM member profi le to help you track meetings, activities, learning, and fi nancial transactions

• Full access to the ASRM Membership Directory

• Access to ASRM’s Career Center to help you fi nd qualifi ed job candidates while enjoying member discounts on job postings—or to help you fi nd that perfect job!

• Full text access to ASRM journals and newsletters online

• Answers to CPT coding questions at the Coding Corner

Thousands of doctors, nurses, and other professionals in the fi eld of reproductive medicine are enjoying the benefi ts of ASRM membership.

If you want to advance your career with the latest news, continuing education, discounts, and networking opportunities, here are some of the reasons you should join:

15 Reasons to Join ASRM Today

Join ASRM today!

• Visit us online at www.asrm.org.• Phone us at + 1-205-978-5000.• Email us at [email protected].• Or visit us at the ASRM booth during our Annual Meeting or

at other selected meetings throughout the year.

59

Free print and online subscriptions to Fertility and Sterility Up to $578Member discount on ASRM eLearn™ Up to $200Member discount on ASRM Annual Meeting Scientifi c Program Up to $275Member discount on ASRM Annual Meeting Postgraduate Courses Up to $80 per courseMember discount rate for posting positions on the ASRM Career Center Up to $113 per postingTotal Value More than $1,000 annually

ASRM Membership Pays for Itself!

Membership also offers savings on patient forms and booklets, ASRM-branded keepsakes, and much more. Given all this value, ASRM membership is an easy fi nancial decision to make.

With the savings and benefi ts ASRM members receive, it’s only a matter of time before your membership pays for itself. Member discounts on meetings, subscriptions, and continuing education credits can add up to more than $1,000 a year.

Join online at www.asrm.org.

Advancing reproductive medicine througheducation, research and advocacy

Write the Next Chapter

Our Fund Development Initiative is a great

opportunity for you to step up and become a

donor and a Champion for the American Society for

Reproductive Medicine. As remarkable as the advances in

reproductive medicine have been over the last 68 years, we

believe the Next Chapter has the potential to yield even

more innovation.

American Society for Reproductive Medicine

For more information onWriting the Next Chapter

funding opportunities, please contact:

Pam NagelASRM Director of Society Advancement

1209 Montgomery HighwayBirmingham, AL 35216

205-978-5000 Ext 121 • [email protected]

60

AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE1209 MONTGOMERY HIGHWAYBIRMINGHAM, AL 35216-2809

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69th American Society for Reproductive Medicine (ASRM) Annual Meeting 2013

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