Nu.Me. - Nutrition and Metabolism8th International Mediterranean Meeting
OBESITY AND DIABETESEPIDEMIOLOGY and PATHOGENESIS
Italian, Japanese and Polish Meeting
PROMOTED BY
University Medical School of Gdańsk Academy of Physical Education of Gdańsk
Danzig (Poland) � May 25-27, 2016
IN COOPERATION WITH
Nagoya University
w w w . f o n d a z i o n e a d i . c o m
The Mediterranean Sea can be defined as an inland sea basin of theAtlantic Ocean, surrounded by Europe to the north, Africa to the south, andAsia to the east. Many consider the Mediterranean to be the most importantcenter in the development of human civilization because the entire history ofthe ancient world evolved and came to an end within its geographicboundaries: more civilizations rose and succeeded each other on its shoresand its islands than in any other part of the globe. The waters of theMediterranean have been a place of unity and of conflict between peoples,and the Mediterranean diet a point of contact and of mutual awareness.
For this reason the “Associazione Italiana di Dietetica e Nutrizione Clinica(ADI)” has considered it timely to open up to this area and to the collaborationbetween the scientific organizations and the experts in the countries that borderthis sea through the holding of an international meeting and the publication ofa scientific review that include the adjective Mediterranean in their title andthat deal with nutrition and metabolism. The first meeting was held in Brindisi,Italy, a logical choice for its geographic position between East and West, andthe interest it aroused encourages us to move ahead.
In a globalized world, the knowledge must be shared and compared; itcan not be limited to a single district. The choice of Danzig as the setting of the8th Meeting is motivated by its historical importance and by its scientifictradition in the fields of nutrition and metabolism. Danzig has a millennialhistory, it was one of the most important cities of the Hanseatic League andexperienced a wide autonomy as a city-state twice. The Medical University ofDanzig provides education to over 5000 students, PhD and postgraduatestudents. The presence of Japanese scientists and researchers emphasizes theimportance of this meeting.
WELCOME MESSAGE
3
The topics addressed will be those of diabetes and obesity, with specialattention given to the most fragile population groups. There is a clear tendencytoward an increase in both the incidence and prevalence of obesity anddiabetes in all the industrialized countries and in the technologicallydeveloping countries. The increased prevalence of type 2 diabetes in the worldhas lead the WHO to speak of a real “epidemic.” Terms such as globesity anddiabesity are now in common use, and the scientific world agrees inrecognizing that if immediate action is not taken there could be very serioushealth problems for millions of people in the next few years. Nutrigenomicsand nutrigenetics are innovative fields of research which should lead us tounderstand increasingly better in what way a food or, better still, particulareating habits, interfere in the functioning of the body at the molecularmetabolic level.
It is a great honor and pleasure for the “Associazione Italiana diDietetica e Nutrizione Clinica” and the “Fondazione ADI” to be able to sharethe experience and the project with the prestigious Medical University ofDanzig and the Nagoya University of Japan, which will make a substantialcontribution to the event‘s success.
Giuseppe FatatiPRESIDENT OF ADI FOUNDATION
4
ChairmenGiuseppe Fatati President of ADI Foundation (Italy)Seiichi Matsuo President of Nagoya University (Japan)Michal Wozniak Medical University of Danzig (Poland)
Local Organizing CommitteeJedrzej Antosiewicz Medical University of Danzig (Poland)Jan Kaczor University School of Physical Education and Sport
Danzig (Poland)Sylwia Malgorzewicz Medical University of Danzig (Poland)Ryszard Smolenski Medical University of Danzig (Poland)Michal Zmijewski Medical University of Danzig (Poland)
Honorary CommitteeLech Wałęsa Nobel Prize Laureate, Former President of Poland Paweł Adamowicz Mayor of the City of Danzig (Poland)Michinari Hamaguchi President of Japan Science and Technology Agency (Japan)Seiichi Matsuo President of Nagoya University (Japan)Jerzy Duszynsk President of Polish Academy of Science (Poland) Janusz Moryś President of Medical University of Danzig (Poland)Waldemar Moska President of University School of Physical Education
and Sport (Poland)Masahide Takahashi Dean of the School of Medicine and Graduate School
of Medicine (Japan) Antonio Caretto President of ADI, Brindisi (Italy)Lucio Lucchin Past President of ADI, Bozen (Italy)
Scientific CommitteeMichal Wozniak Medical University of Danzig (Poland)Jedrzej Antosiewicz Medical University of Danzig (Poland)Giuseppe Fatati President of ADI Foundation (Italy)
Enrico Bertoli Scientific Coordinator ADI Foundation (Italy)Sylwia Malgorzewicz Medical University of Danzig (Poland)Santo Morabito Piemonte Hospital, Messina (Italy) Ryszard Smolenski Medical University of Danzig (Poland)Maria Rita Spreghini Pediatric Bambin Gesù Hospital Rome (Italy)Yoshio Yamauchi School of Medicine and Graduate School of Medicine
Nagoya University (Japan)Wielslaw Ziolkowski University School of Physical Education and Sport
Danzig (Poland)Michal Zmijewski Medical University of Danzig (Poland)
CONTACTSOrganizing Secretariat
Via Angelo da Orvieto, 36 05018 Orvieto (TR) ItalyPhone +39 0763 39 17 51/52Fax +39 0763 34 48 [email protected]
COMMITTEES AND CONTACTS
5
18:00 Opening Ceremony Key note speach
19:30 Welcome reception
THURSDAYMay
26th 2016
08:00 - 09:00 Conference registration
08:30 - 10:40 I Session MARCO POLO SYMPOSIUM Biologically active food components in traditional Italian, Japanese and Polish diet
10:40 - 11:00 Coffee break
11:00 - 13:30 II Session Obesity and Diabetes: epidemiology, pathogenesis and management
13:30 - 14:30 Buffet Lunch
14:30 - 15:45 III Session Nutrigenomics and nutrigenetics. The new paradigma for optiminising health and preventing diseases
15:45 - 17:30 IV Session Vitamin D3 and natural derivatives in health and diseases
20:00 Gala Dinner
FRIDAYMay
27th 2016
PROGRAMME OVERVIEWWEDNESDAY
May25th 2016
08:30 - 10:40 V Session Target functional diet components in ageing and human pathology
10:40 - 11:00 Coffee break
11:10 - 13:05 VI Session Obesity and Diabetes. New and old therapy
13:05 - 13:15 Closing remarks
13:15 - 14:15 Buffet Lunch
13:45 - 17:30 Prof. Jerzy Popinigis Satellite Symposium in memory of Prof. Jerzy Popinigis
6
Jędrzej ANTOSIEWICZ Danzig (Poland)
Marcello ARCA Rome (Italy)
Carmela BAGNATO Matera (Italy)
Agnieszka BARTOSZEK Danzig (Poland)
Maurizio BATTINO Ancona (Italy)
Enrico BERTOLI Ancona (Italy)
Ewa BRYL Danzig (Poland)
Francesco CAPPELLO Palermo (Italy)
Maria Grazia CARBONELLI Rome (Italy)
Antonio CARETTO Brindisi (Italy)
Katarzyna DULIAN Danzig (Poland)
Giancarlo FALCIONI Camerino (Italy)
Giuseppe FATATI Terni (Italy)
Gianna FERRETTI Ancona (Italy)
Damian FLIS Danzig (Poland)
Maria Antonia FUSCO Rome (Italy)
Magdalena GÓRSKA Danzig (Poland)
Tomoya HIROSAWA Nagoya (Japan)
Jan KACZOR Danzig (Poland)
Katarzyna KACZOR Danzig (Poland)
Mateusz KARNIA Danzig (Poland)
Ito KATSUKI Nagoya (Japan)
Narcyz KNAP Danzig (Poland)
Szymon KOWALSKI Danzig (Poland)
Alicja KUBAN-JANKOWSKA Danzig (Poland)
Sergio LEOTTA Rome (Italy)
Dagmara LUBOWIECKA Danzig (Poland)
Lucio LUCCHIN Bozen (Italy)
Monica LUKASZEWICZ Danzig (Poland)
Claudio MACCA Brescia (Italy)
Sylwia MALGORZEWICZ Danzig (Poland)
Elisabetta MANFROI Terni (Italy)
Antonella MARINO GAMMAZZA Palermo (Italy)
Karolina NISKA Danzig (Poland)
Ryszard OLINSKI BYDGOSZCZ (Poland)
Amilcare PARISI Terni (Italy)
Stefano PINTUS Cagliari (Italy)
Alfonso SANTELIA Milan (Italy)
Tomasz SMOLENSKI Warsaw (Poland)
Patrizio TATTI Rome (Italy)
Claudio TUBILI Rome (Italy)
Takashi WAKABAYASHI Nagoya (Japan)
Edyta WERNIO Danzig (Poland)
Jacek WITKOWSKI Danzig (Poland)
Angelika WÓJTOWICZ Danzig (Poland)
Michal WOZNIAK Danzig (Poland)
Roksana WYSZKOWSKA Danzig (Poland)
Yoshio YAMAUCHI Nagoya (Japan)
Ewelina ZIELINSKA Danzig (Poland)
Ewa ZIEMANN Danzig (Poland)
Wiesław ZIÓŁKOWSKI Danzig (Poland)
Michal ZMIJEWSKI Danzig (Poland)
INVITED SPEAKERS
7
SCIENTIFIC PROGRAMMEArtus CourtWEDNESDAY, MAY 25th, 2016
18.00 Opening of the MeetingWelcome by the Authorities
18.30 Key note speachGiuseppe Fatati, Michal Wozniak
19.30 WELCOME RECEPTION
Hall of Medical University of DanzigTHURSDAY, MAY 26th, 2016I SESSIONMarco Polo SymposiumBIOLOGICALLY ACTIVE FOOD COMPONENTS IN TRADITIONAL ITALIAN, JAPANESE AND POLISH DIET MODERATORS: Enrico Bertoli, Jędrzej Antosiewicz
08.00 Conference Registration
08.30 Traditional Italian DietAntonio Caretto
08.55 Traditional active food components of Japanese diet in health and longevity Tomoya Hirosawa
09.20 Healthcare administration of the young leaders' programIto Katsuki
09.45 Sopot as possible smallest Okinawa near Baltic seaMichal Wozniak
10.00 Dietary nucleic acids. A neglected nutrient?Agnieszka Bartoszek
10.15 Legumes: nutritional and healthy properties Gianna Ferretti
10.40 COFFEE BREAK
II SESSIONOBESITY AND DIABETES: EPIDEMIOLOGY,PATHOGENESIS AND MANAGEMENTMODERATORS: Stefano Pintus, Sylwia Małgorzewicz
11.00 Italian realitySergio Leotta
11.25 Alterations of intestinal lipoprotein metabolism in diabetes mellitus and metabolic syndromeMarcello Arca
11.50 The association between albuminuria reduction and renal or cardiovascular protectionSylwia Małgorzewicz
8
12.15 Alpha lipoic acid as nutriceuticalMonika Łukaszewicz
12.40 TechnologyClaudio Tubili
13.05 Discussion
13.30 BUFFET LUNCH
III SESSION NUTRIGENOMICS AND NUTRIGENETICS: THE NEW PARADIGMA FOR OPTIMISING HEALTHAND PREVENTING DISEASESMODERATORS: Lucio Lucchin, Wiesław Ziółkowski
14.30 Nutrigenomics and tasteElisabetta Manfroi
14.55 Novel epigenetic marks of human DNARyszard Olinski Bydgoszcz
15.20 Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling: induction of the lipogenic pathway by a melanoma antigenYoshio Yamauchi
IV SESSIONVITAMIN D3 AND NATURAL DERIVATIVES IN HEALTH AND DISEASESMODERATORS: Maria Grazia Carbonelli, Claudio Tubili, Narcyz Knap
15.45 Bariatric surgery and Vitamin D3Stefano Pintus
16.10 Vitamin D deficiency in health and diseaseMichal Zmijewski
16.35 Nucleotides in metabolic regulationTomasz Smolenski
17.00 Discussion
17.30 Final remarks
20.00 GALA DINNER
SCIENTIFIC PROGRAMME
9
Hall of Medical University of DanzigFRIDAY, MAY 27th, 2016
V SESSIONTARGET FUNCTIONAL DIET COMPONENTS IN AGEING AND HUMAN PATHOLOGY MODERATORS: M. Antonia Fusco, Michał Żmijewski
08.30 Italian functional dietCarmela Bagnato
08.55 Human immune subsystem in ageing; influence of microbiome and dietJacek Witkowski
09.20 Functional diet and human pathologyEwa Bryl
09.45 The healthy effects of polyphenols: which strategy behind antioxidant capacityMaurizio Battino
10.10 Anticancer activity of oleuropein, the component of olive oil, inseparate and combined treatment of main pediatric malignancieswith potent chemotherapeutics - 2 methoxyestradiol and fulvestrantMagdalena Górska
10.25 Dietary components: chicoric, chlorogenic and caffeic acids decrease the activity of protein tyrosine phosphatases - potentialtargets in infectious diseases, diabetes and cancerAlicja Kuban-Jankowska
10.40 COFFEE BREAK
VI SESSIONOBESITY AND DIABETES. NEW AND OLD THERAPYMODERATORS: Claudio Macca, Jacek Witkowski
11.00 Ketogenic DietAlfonso Santelia
11.25 Beneficial components of Polish dietEdyta Wernio
11.50 Whole-body cryostimulation as an effective method of reducinglow-grade inflammation in obese menEwa Ziemann
12.15 Metabolic surgeryAmilcare Parisi
12.40 Early insulinization in type 2 diabetes: is it worthwhile?Patrizio Tatti
13.05 Closing Remarks
13.15 BUFFET LUNCH
SCIENTIFIC PROGRAMME
10
SCIENTIFIC PROGRAMME
15.25 Discussion
15.40 Polyphenols of olive oil as potential anticancer agentsRoksana Wyszkowska
15.50 Prooxidative mechanism of action of peracetic acid in cellular model of acute pancreatitisDagmara Lubowiecka
16.00 Biological effects of metal nanoparticles on prokaryotic and eukaryotic cells Karolina Niska
16.10 Role of inducible nitric oxide synthase in silver nanoparticles - induced toxicityEwelina ZieliŃska
16.20 Assessment of cytotoxic activity newly synthesized coordinationcompounds of vanadyl (VO2+) to pancreatic duct cancer cellsSzymon Kowalski
16.40 Discussion
17.00 A neuroprotective effect of feruleic acidYoung leaders’ presentation
17.30 Conclusions
13.45 Professor Popinigis Memorial Hall Opening Ceremony
14.00 Introduction in Memory of Prof. Jerzy PopinigisTakashi Wakabayashi
14.15 Hepatoprotective effects of Lactobacillus fermentum in mice: a new approach for alcohol use disorders treatmentAntonella Marino Gammazza
14.35 The effect of vitamin D supplementation on oxidative stress in pathologically altered human skeletal muscleKatarzyna Dulian
14.45 The mitochondria protection under exercise condition- the new possible mechanismDamian Flis
14.55 Antitumor activity of newly synthesized N- substituted ebselen derivatives-role of Akt kinaseKatarzyna Kaczor
15.05 Changes in iron metabolism in prostate cancer cells inducedby anticancer compoundsAngelika Wójtowicz
15.15 Chronic psychological stress induces oxidative stress in skeletal muscle in ratsMateusz Karnia
PROF. JERZY POPINIGIS SATELLITE SYMPOSIUMMODERATORS: Giancarlo Falcioni, Francesco Cappello, Jan Kaczor
11
GENERAL INFORMATIONCONFERENCE VENUES
• Wednesday May 25th 2016 Artus Court - Opening Ceremony
The Artus Court is a building in the centre of Danzig whichwas once used to be the meeting place of merchants anda centre of social life. Today it is a branch of the DanzigHistory Museum.
• Thursday May 26th - Friday May 27th 2016Hall of Medical University of Danzig
The Medical University of Danzig is the largest medicalacademic institution in northern Poland. It educates morethan 5000 undergraduate and postgraduate students infour faculties.
CITY OF DANZIGDanzig lies on the Baltic Sea and it is the historical capital ofPomerania. Between the World Wars, the Free City of Danzigwas in a customs union with Poland and was located be-tween German East and Prussia and it was the "Polish cor-ridor" to the sea. Danzig has been part of modern Polandsince 1945.The city was the birthplace of the Solidarity movementwhich, under the leadership of Lech Wałęsa, played amajor role in bringing an end to Communist rule acrossCentral Europe.Most tourist attractions are located along or near Ulica Długa(Long Street) and Długi Targ (Long Market), a pedestrianthoroughfare surrounded by buildings reconstructed inhistorical style.
HOW TO GET TO DANZIGLech Walesa Airport is situated 15 km away from the citycenter. Although it is small, almost all major Europeanairlines serve the airport.www.airport.gdansk.pl
TRANSFER SERVICE The Organizing Secretariat will organize airport transfers bybus (from/to Danzig airport and the hotel). A detailedtimetable will be provided.
CONGRESS LANGUAGEThe conference language is English.
12
HOTEL ACCOMMODATIONThe Organizing secretariat has pre-booked rooms at aspecial rate at
HOTEL MERCUREDANZIG STARE MIASTO ul. Jana Heweliusza 2280-890 Danzig - POLSKA PHONE: +48 58 321 00 53E-mail: [email protected] | accorhotels.com
REGISTRATION FEESYou are kindly requested to register before April 15th 2016.The conference fees are in Euros and must be paid in advance Please pre-register on line at www.viva-voce.it
BEFORE 15 APRIL 2016 AFTER 15 APRIL 2016
ALL DELEGATES EUR 200 EUR 250Trainees/students * EUR 100 EUR 150Accompanying person EUR 100 EUR 150
VAT INCLUDED FOR ALL POLISH DELEGATESITALIAN DELEGATES WITHOUT VAT (privates)
VAT 22% EXCLUDED FORITALIAN COMPANIES ITALIAN DELEGATES WITH VAT (privates)
Single room1 overnight EUR 90Double room1 overnight EUR 110
All rates are per room, inclusive of breakfast and taxes
*A copy of the student card or a certificate by the chairper-son of the department is requested. Please send this infor-mation via e-mail to the Organizing Secretariat
The registration fee includes:Welcome reception of 25 May Access to the scientific sessionsCertificate of attendanceTwo lunches (on 26 & 27 May)Coffee breaksConference kitTransfer services (from/to the airport and the conference venues) Gala dinner of 26 May (only on invitation) Traditional dinner of 27 May The accompanying person fee includes:Welcome reception of 25 MayGuided sightseeing tours of Thursday and Friday Two lunches (on 26 & 27 May)Museum ticketsTransfer services (from/to the airport and the conference venues)Gala dinner of 26 May (only on invitation) Traditional dinner of 27 May
PAYMENTConference fee and hotel accommodation can be paid by:
• Bank transfer to Crediumbria(ref. International NuMe Meeting 2016) IBAN IT55 V070 7525 7010 0000 0900 082Swift code BIC ICRAITRRTVØ• Credit Card (Only Visa - Eurocard - Mastercard)If payment is made by bank transfer, please attach a copyof bank receipt.PAYMENT IS POSSIBLE ONLY IN EURO
GENERAL INFORMATION
Artus Court
13
CANCELLATIONSAll cancellations must be sent to the Organizing Secretariatby e-mail. Payments will be reimbursed if the cancellation isreceived before April 22nd 2016. No reimbursement will begiven if the cancellation is received after April 22nd
ACCOMPANYING PERSONPROGRAMME Sightseeing ToursTHURSDAY May 26th 2016 Departure at 9:00 from the hotel for the excursion to theCastle of the Teutonic Order in Malbork.Guided sightseeing visit to the Castle, inscribed on the worldHeritage List by the World Heritage. This 13th century for-tified monastery belonging to the Teutonic Order was sub-stantially enlarged and embellished after 1309, when theseat of the Grand Master moved here from Venice. A partic-ularly fine example of a medieval brick castle, it later fell intodecay, but was meticulously restored in the 19th and early20th centuries. Following severe damage in the Second WorldWar it was once again restored, using the detailed docu-mentation prepared by earlier conservators.Lunch will be served at a place near the walls of the Castle.The return is scheduled at 5 pm. More detailed information will be provided at the conference.FRIDAY May 27th 2016In the morning guided visit to the Amber Museum, locatedin a listed 14th century Gothic building, used to be a key ele-ment of the medieval fortifications. This is the Fore Gate Com-plex of Długa Street (the so called Danzig Barbican) located inthe Old Town at the crossroads of the major tourist routes.
GENERAL INFORMATION
Castle of the Teutonic Order in Malbork
14
Lunch will be served in a typical restaurant. In the afternoon excursion to the centre of Danzig and tothe main monuments situated along Długa Street and DługiTarg. The Main Town area is the largest Gothic style city onthe Polish territory, represents a historic centre of Danzig. Itsmajority is surrounded by partially retained city walls, bas-tions and gates. This part of the city, including the Old Sub-urb occupies over 115 hectares of land. The Main City grewalong the river Motława and all streets, including Długa andDługi Targ, for centures called the Royal Route, are sloping to-wards the river. The most precious examples of the archi-tecture include mainly: St. Mary’s Church, The Main City Hall,The Artus Court, The Arsenal. More detailed information willbe provided at the conference.
GALA DINNEROn Thursday May 26 at 20:00 there will be a Gala Dinnerat the Danzig ZOO restaurant with traditional Polishdishes. A transfer service will be provided.
GUIDED TOUR FOR DELEGATESOn Friday May 27th in the afternoon, the organizers are plan-ning to offer a guided visit to major sites of interest of Danzig.
PRACTICAL INFORMATIONClimateDanzig has a temperate climate. In May average tempera-tures range from 15 to 20 C. Spring starts in March and is ini-tially cold and windy, later becoming pleasantly warm andoften very sunny. CurrencyThe local currency is Złoty (PLN) exchange rate in Euros is1,00PLN = 0,2275 EUR
Via Angelo da Orvieto, 3605018 Orvieto (TR) Italy
Phone +39 0763 39 17 51/2Fax +39 0763 34 48 80
i n f o @ v i v a - v o c e . i tw w w . v i v a - v o c e . i t
Organizing Secretariat
