A B
C
0
50
100
150
200
FB
G (
mg
/dl)
**
PPAR2LacZ
IB: PPAR
WA
T
Wei
gh
t (g
)
0
0.1
0.2
0.3
0.4
0.5**
Bo
dy
Wei
gh
t
C
han
ge
(g
)
*
0
0.5
1.0
1.5
Uno et al. Figure S1
D E*
Reni
n m
RNA
0
0.5
1.0
1.5
AGT
mRN
A
*
0.5
1.0
1.5
0
KK KK-Ay0
10
20
30
40
50 N S N SB
od
y W
eig
ht
(g)
Uno et al. Figure S2
S100
CGRP
vehicle capsaicin
Uno et al. Figure S3
S100
CGRP
vehicle capsaicin
Uno et al. Figure S4
WA
T W
eig
ht
(g)
0
0.1
0.2
0.3
0.4
N S N S
0
0.1
0.2
0.3
Uno et al. Figure S5
F
D
WA
T w
eig
ht
(g)
0
0.1
0.2
0.3
0.4
**
AFs
p27
mRN
A
PPAR2LacZ
C
FAS
mRN
A
0
1
2
3
**B
SREB
P1c
mRN
A
EU
CP1
mRN
A*
0
1
2
*
0
1
2
Uno et al. Figure S6
G*
0
1
1.5
0.5
Reni
n m
RNA
FB
G (
mg
/dl)
0
50
100
150
200
**
**
0
50
100
150
Fsp
27 m
RN
A
KK-AyKK0
1
2
3
4
**
DIONC
** **
0
5
10
15
Uno et al. Figure S7
