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The Centre of Image Guided Innovation and Therapeutic Intervention (CIGITI) The Hospital for Sick Children University of Toronto, Canada A Bi manual Neuroendoscopic Robot for intraventricular and Skull Base Surgery James M. Drake FRCSC 11th SANS & 2nd APNS Annual Meeting Joint Conference Riyadh April 2017
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The Centre of Image Guided Innovation and

Therapeutic Intervention (CIGITI)

The Hospital for Sick Children

University of Toronto, Canada

A Bi manual Neuroendoscopic Robot for intraventricular and Skull Base Surgery

James M. Drake FRCSC

11th SANS & 2nd APNS Annual Meeting Joint Conference Riyadh April 2017

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Objectives

• Become familiar with the limitations of current neuro-endoscopic instrumentation and training

• Understand the currently available endoscopic simulators and their various advantages and uses.

• Discuss the potential role of robotic tools, informed by models, in advancing the range, efficacy, and outcomes of neuro-endoscopic procedures

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Pre OP Post Op

Computer and Robotic Assisted Resection Thalamic Astrocytoma

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Neurosurgery:1994, 34 (6) - p 1094-1097Instrumentation, Technique, and TechnologyISG Viewing Wand SystemDrake, James M.; Rutka, James T.; Hoffman, Harold J.

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Technical Challenges2-3

– Tools limited to co-axial motion (2-DOF)

– Flexible endoscopes:

• Able to pitch up and down at distal end

• Difficult to maneuver by hand

• Reduced image quality

– Bimanual instrumentation difficult:

• Tools do not meet at a common point

• Tools obstruct view or clash with each other

• Need holder or assistant to position endoscope

– Endoscopes lack stereoscopic vision

Karl Storz LOTTA

Aesculap MINOP InVent

Karl Storz Neuro-Fiberscope

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Technical Challenges2-3

• Difficult to address complex intraventricular pathology:

– Large, firm, vascular tumors

– Difficult-to-access location:

• Posterior third ventricle

• Temporal horn

– Multiple targets/procedures

• Combined pineal region tumor biopsy and ETV

• Choroid plexus cauterization

Schmidek & Sweet Operative Neurosurgical Techniques, 20124-5

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Small exophytic tumourPosterior third ventricle? Metastatic CerebellarPilocytic Astrocytoma

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6 yr old girl, intractable gelastic seizures, failed Gamma Knife treatment. Biggest challenge - “perfect” entry into ventricle – image guidance, ultrasound, etc

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Concentric Tube Robots• Telescoping, pre-curved, superelastic nitinol tubes that when rotated/translated

relative to each other allows precise control of robot shape and position10

• “Snake-like” navigation along complex 3D pathways

Eastwood et al. 201511

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Design Requirements

• Two arms, a camera and a suction device deployed through a 9-mm trocar

• High dexterity (>3DOF)

• Rated force: 0.5 N (required for brain tissue excision)

• Rated speed: 20 mm/sec and 12 rad/sec

• 40mm to 50mm reach

• Sub-millimeter accuracy

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Concentric-Tube Robot (CTR)

• Why?

– Optimum blend of dexterity and stiffness

– Simple to fabricate (miniaturize)

• Working principles

Each superelastic tube actuated by a linear as well as a rotary actuator

Aggregate shape controlled by tubes’ curvatures, stiffness and actuation

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System Overview

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Slave Device

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Linear potentiometer

Rotary potentiometer

Left inner tube carriage

Left outer tube carriage

Right outer tube carriage

Right inner tube carriage

trocar

Grasper actuator

Scissors actuator

1. Trocar2. camera3. Right arm4. Left arm

ID (mm) OD (mm) Curvature (1/mm)

Inner tube 0.94 1.37 0

Outer tube 1.95 2.41 1/80

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Interfacing

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QPID/QPIDe: PCIe-based Hardware-In-The-Loop (HIL) control boards ideal for control prototyping compatible with Matlab and Labview- High bandwidth- Optimized for real-time control- Analogue and digital input/outputs, built-in decoder for quadrature

encoders, 20MHz PWM

potentiometers

Analogue Input

Optical encoders

decoder

Analogue output

motor

Digital output

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Simulator

• Simulator implemented using VRML in Matlab

• Useful for evaluating controller

• Helpful in hardware debugging

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Teleoperation

• Position control (rather than rate control)

• master workspace > slave workspace

• Virtual fixture (reactive force barrier) needed to prevent moving into prohibited areas

• Damping added for stability

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Force barrier

Gravity compensation

damping

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Performance: Dexterity and Reachability

Reachability (reachable workspace)

Dexterity: the ability to move the tip in various directions at any given point

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Stiffness > 2.4 mNm2

i.e. deflection < 5mm for F=0.5 NTip’s rated linear velocity= 20mm/secTip’s rated angular velocity= 12 rad/sec

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Performance: Accuracy

- Tip positions within the workspace measured using NDI Aurora EM tracking system

- Sub-millimeter Sensor accuracy - 85% of data used for kinematic calibration

optimizing- Curvatures- Joint offsets- Registration error

- 15% used for validation

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Performance: Accuracy

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Left arm calibration residuals

Right arm calibration residuals

Left arm validation residuals

Right arm validation residuals

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The Dexter Duo: Demonstration

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2X

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Eastwood KW, Bodani VP, Drake JM. (2015). Three-Dimensional Simulation of Collision Free Paths for Combined Endoscopic Third Ventriculostomy and Pineal Region Tumor Biopsy: Implications for the Design Specifications of Future Flexible Endoscopic Instruments.Oper. Neurosurg.2015 In Press

H. Azimian, T. Looi, J. Drake,. (2015). The Dexter Duo: A Teleoperated Dual-Arm Robotic Neuroendoscope. IEEE Transactions on Mechatronics.

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Conclusions

• The limitations in tools for intraventricular endoscopy preclude the surgical resection of most intraventricular lesions.

• Dextrous robotic tools are a potential solution, but pose a number of technical challenges related to minaturization

• Shape memory alloys employed as concentric tubes manipulators are a viable and robust solution.

• Attachment of standardized endoscopic tools has been implemented.

• Such robotic devices will still require manufacture and testing to regulatory standards.

• Implementation will require significant training and evaluation in which physical models may play an important role.

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Conclusions

• Advances in this area will be particularly relevant to other areas of neurosurgery as well as other surgical specialties

• Demonstrating efficacy, in terms of improved clinical outcomes, will be critical, both for simulation training, and novel tools, to justify their investment and costs.


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