Roche internship in Medicinal CHemistry – RiCH – Dr. Matthias Nettekoven, RiCH program director
Therapeutic Modalities Medicinal Chemistry Pharma Research and Early Development
Roche Innovation Center Basel, Switzerland
A chance in a lifetime?
Dr. Matthias Nettekoven -my way to Roche-
Postdoc
Prof. S. V. Ley
Cambridge, England
Principal scientist in
Medicinal Chemistry
Program director for Roche
internship in Medicinal
Chemistry program
Basel, Switzerland
student – chemistry
Bonn, Germany
PhD student
Prof. H. Waldmann, MPI
Boehringer Ingelheim, Germany
Roche internship in Medicinal CHemistry -RiCH-
The next Roche internship in Medicinal CHemistry (RiCH), in Basel Switzerland starts on
1. September 2018 and will last 12 months (until end of August 2019)
You are a chemistry student in a University who in the 2018-2019 academic year will be in the penultimate or last
year of study or at the “Year in Industry” junction of your studies
You are highly a motivated student with a strong enthusiasm for Organic and Medicinal Chemistry
You have to apply through careers.roche.com until Friday, 6. October 2017
You have to provide your CV, a motivational letter and one academically relevant letter of recommendation
We will interview selected candidates either in person at their University or via Video-link (webex, skype,..). We
would like to get to know you and will ask technical and personal questions
Interviews will be performed during October 2017 and the decision will be communicated shortly afterwards
Basel / Switzerland @ the heart of Europe
Basel / Switzerland @ the heart of Europe
Basel and the river Rhine
Roche site in Basel Medicinal Chemistry building, Roche Basel
Roche internship in Medicinal CHemistry -RiCH- what is it about?
Unique in a special way – you will be part of one of the largest diverse groups of University interns in the
pharmaceutical industry and have the opportunity to widen your scientific network significantly
You will refine your skills which are required to become a successful professional scientist
Development of further key skills - you will receive a specially designed tuition program to greatly enhance
your scientific thinking /discussing ability and presentation skills
RiCH students work in chemistry laboratories within our project teams - you will be fully
integrated and be exposed to key elements of Modern Medicinal Chemistry & Drug Discovery @ Roche
Collaboration - you will work in a matrix organisation and interact with chemists, biologists, molecular design
scientists et al. and at the end of RiCH 2018 be able to define your next steps much more clearly
And we support you in this endeavour
Roche internship in Medicinal CHemistry -RiCH- a typical day @ Roche
08:30 11:00 12:00
13:00 15:00 15:30 17:30
Arrive at Roche and set-up
your reaction(s)
Reaction analysis via
LCMS & TLC
Perform reaction work-up
if complete
Lunch break
Purification of
crude material
Final analysis of
pure compound
Submission to
analytics / biology
Update ELN, assign NMRs, order
chemicals, produce powerpoints for group
meetings, read literature, plan reactions, . .
.
o Likely work later
o Set-up reactions
o Roche work
o Uni work
o Return home
Roche internship in Medicinal CHemistry -RiCH- the tuition program -to educate and to entertain-
The tuition program will make you more proficient, efficient and focussed in presenting and handling
discussions. It prepares you for the day that someone asks THE chemistry question.
We will meet every two weeks on Thursdays at 16.00h for 2h
We will have synthesis discussions, labletters, functional group chemistry discussion, . . .
You will frequently present your contribution to the other students (pechakucha)
We have two poster sessions in the Medicinal chemistry department and you show your work
Additionally, you will regularly present your contribution in the individual project teams
Roche Internship in Medicinal Chemistry tuition program -to educate & to entertain-
31.08.17; B001-28 Welcome & apero 22.02.18; cafeteria B92 Poster session & Bergfest
07.09.17, B92/56 Basics @Roche, Matthias 01.03.18; B92/56 EQ rules for success
14.09.17; B92/56 The top 20, Thomas 15.03.18; B92/56 20/10/20
21.09.17; B92/56 Analytics & MDO @ Roche, Inken & Patrizio 30.03.18 Gruendonnerstag 1.4 / 2.4.18 Easter
27.09.17 two slots Fire fighting course 12.04.18; B92/56 LabLetter 2
28.09.17; B92/56 Special 20/10/20 26.04.18; B92/56 Functional groups group 1&2
05.10.17; B92/56 20/10/20 03.05.18; B92/56 Functional groups group 3&4
12.10.17; B92/56 Synthesis discussion, group 1&2 17.05.18; B92/56 20/10/20
26.10.17; B92/56 Synthesis discussion, group 3&4 10.05. Ascension day 20.5 / 21.5 Pentecost
09.11.17; B92/56 LabLetter 1 31.05.18; B92/56 MedChem vs process, group 1&2
23.11.17; B92/56 Functional groups group 1&2 14.06.18; B92/56 MedChem vs process, group 3&4
07.12.17; B92/56 Functional groups group 3&4 28.06.18; B92/56 LabLetter 3
11.01.18; B92/56 The top 20 refresher, Thomas 12.07.18; B92/56 20/10/20
25.01.18; B92/56 Synthesis discussion, group 1&2 26.07.18, cafeteria B92 Poster session & farewell party
08.02.18; B92/56 Synthesis discussion, group 3&4 02.08.18; B92/56 Tips & tricks
12.2.18 Rosenmontag 19.2.18 Basler Fasnacht 09.08.18; B92/56 chemistry quiz & feedback, Thomas
always: Thursday 4pm (duration: less then 90 min)
Roche internship in Medicinal CHemistry -RiCH- Is it only work?????
All RiCH students will life together in one appartment block with individual rooms, en-suite facilities, a
shared kitchen and meeting room. This is almost in the city center of Basel which makes commuting easy
Cost of living is high in Switzerland and you will receive a «decent» monthly salary
Many apéros / activities on site where students are 100% welcome
Frequent social events @ pRED, Basel site, MedChem (happy hours, skidays, summerparty, X-mas party, ...)
Roche Sports Club (Football, Badminton, scuba-diving, golf, ...)
Things to discover:
Basel is in the center of Europe & it’s an easyjet hub . . .
Switzerland and hiking / skiing goes together
Roche internship in Medicinal CHemistry -RiCH- some facts were you might wonder…
Do I need to speak German??
Is it daunting to move to Switzerland??
How do I know when to do what??
How many holiday days do I have?
Not necessarily, however learning a few simple German phrases can be helpful! Bitte, Danke, Ein Kaffee bitte . . .
We will support you with anything you will need. Work contract, ‘L permit’, bank account, Swiss SIM, health
insurance, Halbtax travelcard, …
Don’t worry - we have done it before!
23-25 days, may be taken however you like!
We will keep in touch with you and inform you ahead of time. If in question, be in contact!!
Roche internship in Medicinal CHemistry -RiCH- Career advice and support
You get a lot of support for how to prepare an impactful application (cover letter, cv, research
summary) for the next step in your career
Currently, every two years two students are selected to receive an EFMC-Roche studentship award
The internship program is NOT designed as a 1 year job interview
We encourage and support top students to continue to do a PhD
Roche internship in Medicinal CHemistry -RiCH- The five RiCH…
Dr Thomas Woltering
RiCH tutor
Vanessa Casonato
RiCH admin
Dr Matthias Nettekoven
RiCH program director
Dr Hayley Binch
Head of Medicinal Chemistry Basel
Dr Fionn O’Hara
RiCH tutor
Roche internship in Medicinal CHemistry -RiCH-
And now we ask RiCH 2016
September 2016
Your CV is the first impression you leave !
Think about how you can add value to Roche
Roche internship in Medicinal CHemistry -RiCH-
The next step is yours!
You apply with CV, cover letter and ONE academically relevant letter of support
Henni said: your motivation is key!!!
Doing now what patients need next
