Date post: | 27-Dec-2014 |
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A Day in the Life of a Clinical Laboratory Animal Veterinarian
Research Opportunities Fun Facts
Provide for the health and well-being of animals used in research and testing
Laboratory Animal Medicine
Study of biology and disease in animal models to improve human and animal health
Comparative Medicine Research
Research Clinical Medicine Pathology and
Diagnostics Surgery Teaching and
Training Administration Diverse and
interesting jobs
Research
SurgeryPathology
Clinical Medicine
No two days are the same! Multiple components to a clinician’s job
Veterinary Care Husbandry Oversight Model Development/Refinement Investigator Collaboration/Support Training Compliance
Protocol Review Post-Approval Monitoring Training
Wide variety of species
Herd Health Preventative Medicine
Dog/Cat NHP Rodent
Outbreak Management Research Outcomes vs. Treatment Options
Will a treated animal still be a useful research model?
Model related disease vs. spontaneous disease
You are the “Expert”! Wide variety of species Regulatory Component
Cage size – USDA, The Guide for Care and Use of Laboratory Animals
Changing/Sanitization frequency Animal Wellbeing Diet Bedding Types Breeding Concerns All must be kept in the context of the
research they are supporting!!!!!!!
“Hey Doc, I want to study heart disease in… Mouse Rat PigHow do I do it?”
“Hey Doc, I have this mouse that gets heart disease, but it doesn’t show the signs I need it to. Any thoughts?”
How can you help? This is where you can really help
investigators by standing in the hallway and talking to them. Communication is the KEY!
Alternatives to animal models How can you help?
3 (4) R’s Reduce the number of animals used Refine methods Replace animal models with other systems (Respect)
Model Development/Refinement Model Support
Surgical Model Development (VAP placement) Specialized Veterinary Needs (DMD) Technical Support/Training
Breeding Colony Problems Training
PI and their staff Graduate students Veterinary students Public at large
Animal Care and Use Committee (ACUC) Animal Use Protocols
Pre-review
Animal Care Quality Assurance Post-Approval Monitoring Compliance Animal welfare concerns
Best cure for most compliance issues is an ounce of prevention (lots of communication and training!)
Coupling of interests Veterinary medicine Research
Post-DVM programs devoted to training in research and veterinary specialties Examples of research-oriented specialties
American College of Laboratory Animal Medicine (ACLAM)
American College of Veterinary Pathology (ACVP) High demand / good pay Variety of career opportunities
Develop hypotheses Perform investigations Observe and interpret outcomes Establish conclusions Prepare grants and manuscripts Become experts in their fields
Peter Doherty, DVM, PhD
Nobel Laureate, 1996
Basic Clinical / Applied
Veterinary Questions Human Health Questions
Primary Investigators Collaborative Scientists
TranslationalResearch
}
}One HealthOne Medicine
One health initiativehttp://onehealthinitiative.com/index.php
Technology development for organ transplantation
Examples of Comparative Medicine Research
Development for mouse models of cancer metastasis
Example of Micro-CT Image Data
Volume rendering of Micro-CT image
data.
CTI-Concorde LLCMicroCAT II™
Micro-CTMicro-CT Coronal
Section
Day 21 Day 27 Day 35 Day 43
Progression of a Tibial Metastasis
0.75 mm 1.4 mm 2.3 mm
?
Day 27
0.75 mm
Day 21
Progression of a Tibial Metastasis
Anywhere biomedical research is performed Universities Pharmaceutical
companies Biotech companies Government All over the country / world Travel!
Great!!! Future stil bright
0-5 years experience (ACLAM) Ave (2005) = $71,000(non-dipl)-$96,000(dipl) Highest = $150,000 (dipl)
Ave = $133,803 (ACLAM) Consulting to supplement
Ave = $16,698 Residency Salaries
Start at $36,996 Post DVM/PhD training (SERCA)
Up to $75,000
http://www.aclam.org/print/2005SalarySurveyFinal.pdf
Independent and Collaborative Research
Improving human and animal life
Veterinary Care Development and refinement of
animal models Development of alternatives to
animals
Externships / electives Comparative Medicine Clubs Student member of
ASLAP, ACVP, etc Meeting opportunities
Talk to Comparative Medicine Scientists and Laboratory Animal Veterinarians
Post-DVM training programs
What? 3-12 weeks Summer research programs Flexible Many are paid!!!!!
Where? Academia – training programs Biotech & pharmaceutical
companies NIH, USDA Primate centers
How to find? Visit the web
http://cvm.msu.edu/research/summer-research-program-1/merck-merial-veterinary-scholars/merck-merial-veterinary-scholars-national-and-canadian-research-opportunities-for-veterinary-students
Research “Residency”
hands on no internship
required Various
combinations Each program
has it’s strengths
Advantages Perspective to
research Comparative Clinician scientist Research teams
Coupling of interests
Dedicated funding sources for training
Disadvantages? Time well spent!
Visit the web Talk to Comparative Medicine Scientists
and Laboratory Animal Veterinarians Do an externship!!!!!!
DVM Graduate training (MS, PhD, postdoc)
Residency
Research
Research
Combined programs (DVM/PhD)
Combined programs (resident/grad)
Practice
Exciting careers Great job market Neat toys Great
environment
Questions?