+ All Categories
Home > Documents > A novel approach using the enhanced-view totally ...A novel approach using the enhanced-view totally...

A novel approach using the enhanced-view totally ...A novel approach using the enhanced-view totally...

Date post: 30-Jan-2021
Category:
Upload: others
View: 4 times
Download: 0 times
Share this document with a friend
8
A novel approach using the enhanced-view totally extraperitoneal (eTEP) technique for laparoscopic retromuscular hernia repair Igor Belyansky 1 Jorge Daes 2,3 Victor Gheorghe Radu 4 Ramana Balasubramanian 5 H. Reza Zahiri 6 Adam S. Weltz 6 Udai S. Sibia 6 Adrian Park 6,7 Yuri Novitsky 8 Received: 21 March 2017 / Accepted: 22 August 2017 / Published online: 15 September 2017 Ó Springer Science+Business Media, LLC 2017 Abstract Background The enhanced-view totally extraperitoneal (eTEP) technique has been previously described for Laparoscopic Inguinal Hernia Repair. We present a novel application of the eTEP access technique for the repair of ventral and incisional hernias. Methods Retrospective review of consecutive laparoscopic retromuscular hernia repair cases utilizing the eTEP access approach from five hernia centers between August 2015 and October 2016 was conducted. Patient demographics, hernia characteristics, operative details, perioperative complications, and quality of life outcomes utilizing the Carolina’s Comfort Scale (CCS) were included in our data analysis. Results Seventy-nine patients with mean age of 54.9 years, mean BMI of 31.1 kg/m 2 , and median ASA of 2.0 were included in this analysis. Thirty-four percent of patients had a prior ventral or incisional hernia repair. Average mesh area of 634.4 cm 2 was used for an average defect area of 132.1 cm 2 . Mean operative time, blood loss, and length of hospital stay were 218.9 min, 52.6 mL, and 1.8 days, respectively. There was one conversion to intraperitoneal mesh placement and one conversion to open retromuscular mesh placement. Postoperative complica- tions consisted of seroma (n = 2) and trocar site dehis- cence (n = 1). Comparison of mean pre- and postoperative CCS scores found significant improvements in pain (68%, p \ 0.007) and movement limitations (87%, p \ 0.004) at 6-month follow-up. There were no readmissions within 30 days and one hernia recurrence at mean follow-up of 332 ± 122 days. Conclusions Our initial multicenter evaluation of the eTEP access technique for ventral and incisional hernias has found the approach feasible and effective. This novel approach offers flexible port set-up optimal for laparo- scopic closure of defects, along with wide mesh coverage in the retromuscular space with minimal transfascial fixation. Keywords Ventral and incisional hernia repair Á Abdominal wall reconstruction Á Retromuscular mesh placement Á Transversus abdominis release Á Enhanced- view totally extraperitoneal technique Presented at the SAGES 2017 Annual Meeting, March 22–25, 2017, Houston, Texas. & Adam S. Weltz [email protected] Igor Belyansky [email protected] 1 Department of Surgery, Anne Arundel Medical Center, 2000 Medical Parkway, Belcher Pavilion, Suite 106, Annapolis, MD 21401, USA 2 Department of Surgery, Clinica Bautista and Clinica Portoazul, Barranquilla, Colombia 3 Minimally Invasive Surgery Department, Clinica Portoazul, Barranquilla, Colombia 4 Surgical Department Life Memorial Hospital, Bucharest, Romania 5 Department of Comprehensive Hernia Surgery, Medica Superspecialty Hospital, Kolkata, India 6 Department of Surgery, Anne Arundel Medical Center, Annapolis, MD, USA 7 Johns Hopkins School of Medicine, Baltimore, MD, USA 8 Department of Surgery, University Hospital Cleveland Medical Center, Cleveland, OH, USA 123 Surg Endosc (2018) 32:1525–1532 https://doi.org/10.1007/s00464-017-5840-2 and Other Interventional Techniques
Transcript
  • A novel approach using the enhanced-view totally extraperitoneal(eTEP) technique for laparoscopic retromuscular hernia repair

    Igor Belyansky1 • Jorge Daes2,3 • Victor Gheorghe Radu4 • Ramana Balasubramanian5 •

    H. Reza Zahiri6 • Adam S. Weltz6 • Udai S. Sibia6 • Adrian Park6,7 •

    Yuri Novitsky8

    Received: 21 March 2017 / Accepted: 22 August 2017 / Published online: 15 September 2017

    � Springer Science+Business Media, LLC 2017

    Abstract

    Background The enhanced-view totally extraperitoneal

    (eTEP) technique has been previously described for

    Laparoscopic Inguinal Hernia Repair. We present a novel

    application of the eTEP access technique for the repair of

    ventral and incisional hernias.

    Methods Retrospective review of consecutive laparoscopic

    retromuscular hernia repair cases utilizing the eTEP access

    approach from five hernia centers between August 2015

    and October 2016 was conducted. Patient demographics,

    hernia characteristics, operative details, perioperative

    complications, and quality of life outcomes utilizing the

    Carolina’s Comfort Scale (CCS) were included in our data

    analysis.

    Results Seventy-nine patients with mean age of 54.9 years,

    mean BMI of 31.1 kg/m2, and median ASA of 2.0 were

    included in this analysis. Thirty-four percent of patients

    had a prior ventral or incisional hernia repair. Average

    mesh area of 634.4 cm2 was used for an average defect

    area of 132.1 cm2. Mean operative time, blood loss, and

    length of hospital stay were 218.9 min, 52.6 mL, and

    1.8 days, respectively. There was one conversion to

    intraperitoneal mesh placement and one conversion to open

    retromuscular mesh placement. Postoperative complica-

    tions consisted of seroma (n = 2) and trocar site dehis-

    cence (n = 1). Comparison of mean pre- and postoperative

    CCS scores found significant improvements in pain (68%,

    p\ 0.007) and movement limitations (87%, p\ 0.004) at6-month follow-up. There were no readmissions within

    30 days and one hernia recurrence at mean follow-up of

    332 ± 122 days.

    Conclusions Our initial multicenter evaluation of the eTEP

    access technique for ventral and incisional hernias has

    found the approach feasible and effective. This novel

    approach offers flexible port set-up optimal for laparo-

    scopic closure of defects, along with wide mesh coverage

    in the retromuscular space with minimal transfascial

    fixation.

    Keywords Ventral and incisional hernia repair �Abdominal wall reconstruction � Retromuscular meshplacement � Transversus abdominis release � Enhanced-view totally extraperitoneal technique

    Presented at the SAGES 2017 Annual Meeting, March 22–25, 2017,

    Houston, Texas.

    & Adam S. [email protected]

    Igor Belyansky

    [email protected]

    1 Department of Surgery, Anne Arundel Medical Center, 2000

    Medical Parkway, Belcher Pavilion, Suite 106, Annapolis,

    MD 21401, USA

    2 Department of Surgery, Clinica Bautista and Clinica

    Portoazul, Barranquilla, Colombia

    3 Minimally Invasive Surgery Department, Clinica Portoazul,

    Barranquilla, Colombia

    4 Surgical Department Life Memorial Hospital, Bucharest,

    Romania

    5 Department of Comprehensive Hernia Surgery, Medica

    Superspecialty Hospital, Kolkata, India

    6 Department of Surgery, Anne Arundel Medical Center,

    Annapolis, MD, USA

    7 Johns Hopkins School of Medicine, Baltimore, MD, USA

    8 Department of Surgery, University Hospital Cleveland

    Medical Center, Cleveland, OH, USA

    123

    Surg Endosc (2018) 32:1525–1532

    https://doi.org/10.1007/s00464-017-5840-2

    and Other Interventional Techniques

    http://crossmark.crossref.org/dialog/?doi=10.1007/s00464-017-5840-2&domain=pdfhttp://crossmark.crossref.org/dialog/?doi=10.1007/s00464-017-5840-2&domain=pdfhttps://doi.org/10.1007/s00464-017-5840-2

  • Prior to 1993, ventral hernias were repaired exclusively

    through open approaches. Pioneers including LeBlanc,

    Booth, Heniford, Park, Ramshaw, and Voeller subse-

    quently described the laparoscopic approach to ventral

    hernia repair (LVHR), where a barrier mesh is placed in the

    intraperitoneal underlay position [1, 2]. This repair relies

    on wide mesh overlap, penetrating fixation with tacks and

    transabdominal stitches without defect closure. Soon the

    advantages of LVHR over the open approach became

    obvious, most notably, reduced wound complication rates

    and faster recovery. With further experience, some sur-

    geons began incorporating primary closure of the defect in

    LVHR [3]. The decision of whether to close the primary

    fascial defect at the time of hernia repair may still be

    debatable. However, defect closure is gaining support due

    to presumed restoration of the anatomy, physiology, and

    cosmesis of the abdominal wall [4, 5].

    While the LVHR repair has lasted more than two

    decades, it has not been without limitations. These

    include rare but serious complications such as adhesive

    bowel obstruction, mesh erosion, and enterocutaneous

    fistula from direct contact between the mesh and

    intraperitoneal viscera [6, 7]. To address this, the trans-

    abdominal preperitoneal (TAPP) approach to ventral and

    incisional hernias has been described [8]. This technique

    has the difficulty of elevating and closing thin peritoneal

    flaps, a laparoscopic technique that is challenging to

    reproduce even in the most experienced hands. Belyansky

    et al. recently described laparoscopic Transversus Abdo-

    minis Release (l-TAR), a reconstructive technique

    restoring the linea alba with retromuscular mesh rein-

    forcement. Similarly to TAPP repairs, l-TAR prevents

    direct mesh contact with viscera [9]. Despite early suc-

    cess, we found the intracorporeal closure of the defects

    challenging with traditional port placement lateral to

    linea semilunaris.

    The enhanced-view totally extraperitoneal (eTEP)

    technique has been previously described for laparoscopic

    inguinal hernia repair [10, 11]. The salient features of this

    technique are rapid and facile creation of extraperitoneal

    domain, large operative space, flexible port set-up, and

    improved tolerance of pneumoperitoneum. It was designed

    to facilitate learning and mastering of the procedure for the

    novel surgeon and for complex cases such as large

    inguinoscrotal, sliding, or incarcerated inguinal hernias, as

    well as obese or post-bariatric patients and those with

    previous pelvic surgeries or a short distance between

    umbilicus and pubic tubercle [10, 11].

    This study aims to present a novel application of the

    Enhanced-view Totally Extraperitoenal access technique

    for the repair of ventral and incisional hernias.

    Methods

    Study design

    Institutional review board approval was obtained to per-

    form a retrospective review of electronic medical records

    in order to identify all patients who underwent laparoscopic

    eTEP repair of their ventral or incisional abdominal wall

    hernias between August 2015 and October 2016. Five

    hernia centers participated in this study: Anne Arundel

    Medical Center in Annapolis, Maryland (n = 50);

    University Hospital Cleveland Medical Center in Cleve-

    land, Ohio (n = 8); Clinica Bautista and Clinica Portoazul

    in Colombia, South America (n = 4); Life Memorial

    Hospital in Bucharest, Romania (n = 6); and Medica

    Superspecialty Hospital, Kolkata, India (n = 11).

    Patient demographics, hernia characteristics, and peri-

    operative and postoperative data were analyzed. Main

    outcomes measured included perioperative complications,

    length of stay, 30-day readmissions, and hernia recur-

    rences. Wound and systemic complications included ser-

    oma, hematoma, cellulitis, abscess, skin necrosis, wound

    dehiscence and mesh infection, ileus ([5 days post-sur-gery), urinary tract infection (UTI), acute renal insuffi-

    ciency (ARI), venous thromboembolism (VTE), respiratory

    complications (atelectasis, pneumonia, etc.), myocardial

    infarction (MI), and congestive heart failure (CHF), as well

    as perioperative complications.

    CCS surveys were routinely prospectively collected for

    hernia patients at Anne Arundel Medical Center. The other

    centers had not incorporated CCS surveys into their prac-

    tice. Subset analysis was performed to assess quality of life

    (QOL) outcomes utilizing the Carolinas Comfort Scale

    (CCS) for all patients from Anne Arundel Medical Center

    [12]. The CCS is a validated hernia-specific survey that

    utilizes a 0–5 scale to assess pain, mesh sensation, and

    limitations in mobility. A significant score in any of the

    three measured CCS parameters has been previously

    defined as C2 out of 5 [13] and was used for our analysis.

    Preoperative workup/patient selection

    The preoperative workup for all hernia patients is stan-

    dardized at our centers beginning with a detailed history,

    physical examination, and biochemical studies to assess

    their baseline health. Specific to this patient population,

    defect location and size, prior or current wound compli-

    cations, presence of ostomy, excess skin, and contour

    abnormalities are part of the physical exam and are con-

    sidered in selection of the proper operative approach for the

    patient.

    1526 Surg Endosc (2018) 32:1525–1532

    123

  • Given frequent incidence of recurrent hernias, special

    effort and attention is paid to review of prior medical and

    surgical records to gain a thorough understanding of their

    previous interventions, anatomy, and the presence of any

    mesh or fixation devices. All patients undergo a computed

    tomography (CT) study of their abdomen and pelvis for

    preoperative hernia measurement and operative planning.

    Patients with previous incision extending from xiphoid

    process to the pubic bone are a relative contraindication to

    eTEP access technique and are typically addressed with

    transabdominal laparoscopic approach. Those with loss of

    domain and dystrophic or ulcerated skin are also consid-

    ered to have a relative contraindication for eTEP access

    approach. Patients with active mesh infection and fistula

    presence have an absolute contraindication to eTEP and

    MIS intervention. All other patients are considered candi-

    dates for the eTEP access retromuscular approach with or

    without TAR.

    Operative technique

    After induction of general anesthesia and intubation, Foley

    catheter is routinely placed and bilateral upper extremities

    are tucked at patient’s sides. The OR table is flexed as

    demonstrated in Fig. 1. The eTEP access approach relies

    on initiating the dissection in one of the retrorectus spaces

    and then crossing over to contralateral retrorectus space,

    thus connecting the two spaces. The decision where to

    crossover as well as initial port set-up depends on the

    defect location and described in the sections that follow.

    Upper midline defects

    When dealing with upper midline defects, we prefer to

    perform the crossover below the level of the umbilicus,

    developing preperitoneal and retromuscular space that has

    not been previously violated. Figure 2 demonstrates the

    port position for upper midline defects. The first incision is

    made just 2 cm bellow a horizontal line drawn through

    umbilicus and just medial to linea semilunaris. The anterior

    rectus sheath is identified and incised sharply. Single-site

    balloon dissector is used to develop the retrorectus space in

    cephalad and caudal directions. It is critical to avoid over-

    inflation which may rupture the linea semilunaris and

    consequently injure rectus abdominis muscle. Once the

    space of Retzius is developed, ports #2 and 3 are placed

    under direct vision in the lower abdomen. A 30-degree

    scope is placed through port #3 and we then proceed with

    the retrorectus dissection heading in the cephalad direction

    (Fig. 3). Bilateral posterior rectus sheathes are identified

    and released from caudal to cephalad direction thus con-

    necting retrorectus spaces (Fig. 4).

    Fig. 1 Proper flexion of OR table

    Fig. 2 Port position for upper midline defects

    Fig. 3 Dissection heading in cephalad direction

    Surg Endosc (2018) 32:1525–1532 1527

    123

  • Lower midline defects

    For a right-handed surgeon, we found that lower midline

    defects are easier to address by initiating the dissection in

    the upper portion of left retrorectus space. Figure 5

    demonstrates the typical port position that we chose to use

    for this approach. Balloon dissector is used at port 1

    position to develop left retrorectus space, under direct

    vision ports 2 is placed into the developed space, and port 3

    can be optional. Blunt dissection in the left retrorectus

    space is performed in caudal direction and pubis is iden-

    tified. Considering that upper midline has not been previ-

    ously violated, above the level of umbilicus, medial aspect

    of left posterior rectus sheath is incised and preperitoneal

    space is entered, just superficial to Falciform ligament

    (Fig. 6). Right posterior rectus sheath is identified and

    medial aspect of it is incised and released from cephalad to

    caudal direction (Fig. 7) followed by blunt dissection in the

    right retrorectus space. Port 4 is then placed under direct

    vision through the upper aspect of right rectus abdominis

    muscle; this then becomes the camera port. The retrorectus

    dissection is carried out in the caudal direction completing

    bilateral release of posterior rectus sheathes. When

    encountering the hernia sac, we try to sharply dissect the

    distal attachments of the sac, thus mobilizing it down.

    Alternatively, the sac can be sharply entered and laparo-

    scopic adhesiolysis is performed as needed.

    For more challenging defects that require large mesh

    placement, the TAR procedure is added [9, 14]. The

    incorporation of TAR was found beneficial in cases with

    wide ([10 cm) defect, tension on the posterior layer, nar-row retrorectus space (\5 cm), or when dealing with a

    Fig. 4 Connecting retrorectus spaces

    Fig. 5 Port placement for lower midline defects

    Fig. 6 Medial aspect of left posterior rectus sheath is incised andpreperitoneal space is entered, just superficial to Falciform ligament

    Fig. 7 Right posterior rectus sheath is identified and medial aspect ofit is incised and released from cephalad to caudal direction

    1528 Surg Endosc (2018) 32:1525–1532

    123

  • poorly compliant abdominal wall. Any defects in posterior

    layer are closed with 2-0 absorbable suture. The abdominal

    wall defect is primarily closed using 0 barbed suture in

    running fashion, while pneumoperitoneum is dropped to

    8 mm Hg (Fig. 8).

    Finally, the developed retrorectus/preperitoneal space is

    measured for appropriate mesh size selection. Our prefer-

    ence is medium weight macroporous polypropylene mesh,

    deployed through our 12-mm trocar. Mesh is positioned to

    widely cover the developed space. Mesh can be secured

    with several transfascial sutures, tacks, or 10 mL fibrin

    sealant glue. In our more recent experience, some of us

    have migrated to no fixation. Pneumoperitoneum is

    released under direct vision assuring that the mesh is laying

    flat between the posterior and anterior layers.

    Results

    Seventy-nine patients (n = 34 Male, n = 45 Female) with

    mean age 54.9 years, mean BMI 31.1 kg/m2, and median

    ASA score 2.0 were included in this review. Thirty-four

    percent of patients had prior ventral or incisional hernia

    repairs. The most frequent comorbidities in our patients

    were hypertension (46%) and diabetes (19%). Table 1 is a

    complete summary of relevant patient demographics.

    Primary operations performed were eTEP access Rives

    Stoppa Repair n = 38 (48%) and eTEP access TAR

    n = 41 (52%). A variety of mesh fixation techniques were

    utilized, with fibrin glue used in the majority of cases

    (75%) to secure the mesh to the posterior fascial layer.

    Mean operative time, intraoperative blood loss, and LOS

    for the entire cohort were 218.9 min, 52.6 mL, and

    1.8 days, respectively (Table 2). Mean defect width, area,

    and LOS were also broken down for both Rives Stoppa and

    TAR cases (Table 3).

    Table 4 lists complications. Intraoperative complica-

    tions included one muscle rupture during initial balloon

    dissection requiring conversion to LVHR procedure and

    Fig. 8 Abdominal wall defect is primarily closed using 0 barbedsuture in running fashion under conditions of reduced

    pneumoperitoneum

    Table 1 Patient demographics

    Variable eTEP approach

    N 79

    Age (years) 54.9 ± 13.9

    Body mass index (kg/m2) 31.1 ± 6.0

    ASA score 2.3 ± 0.6

    Prior incisional hernia repair 34%

    Gender (male/female) 43%/57%

    Hypertension 46.0%

    Diabetes mellitus 19.0%

    Hyperlipidemia 14.0%

    Active smoker 6.0%

    Coronary artery disease 4.0%

    COPD 4.0%

    History of stroke/CVA 3.0%

    History of myocardial infarction 3.0%

    Congestive heart failure 3.0%

    Immunocompromised 1.0%

    Alcoholism 1.0%

    ASA American Society for Anesthesiologists

    Table 2 Perioperative data

    Variable eTEP approach

    Surgical procedure

    Rives Stoppa n = 38 (48.0%)

    TAR n = 41 (52.0%)

    Mean surgical time (mins) 218.9 ± 111.2

    Mean estimated blood loss (mL) 52.6 ± 39.5

    Mean defect area (cm2) 132.1 ± 134.2

    Mean mesh area (cm2) 634.4 ± 319.7

    Median defect area (cm2) 100

    Mean LOS (days) 1.8 ± 1.8

    Mesh fixation

    None 7.0%

    Fibrin glue alone 75.0%

    Tacks 1.0%

    Suture 9.0%

    Fibrin glue and suture 4.0%

    Fibrin glue and tacks 1.0%

    Suture and tacks 3.0%

    Surg Endosc (2018) 32:1525–1532 1529

    123

  • one conversion to open transversus abdominis release to

    facilitate excision of a suspicious bone fragment in a

    patient with a recurrent incisional hernia and prior history

    of bowel obstructions.

    The incidence of 30-day wound-related complications

    was 3.8%. There were no non-wound-related complica-

    tions. Two patients presented with retromuscular seromas

    within 30 days of their index operation, one managed with

    observation and one required percutaneous drainage by

    interventional radiology. Another patient presented with

    wound dehiscence of a trocar site requiring local wound

    care. There were no readmissions or reoperations at a mean

    follow-up of 322 ± 122 days. There was one recurrence in

    a TAR patient that was diagnosed at 1-year follow-up.

    More than half of our patients reported pain (58.5%) and

    movement limitations (46.3%) prior to surgery according

    to CCS data analysis. Comparison of mean pre- and post-

    operative CCS scores (Table 5) found significant

    improvements in pain (60%, p\ 0.002) and movementlimitations (66%, p\ 0.004) at 1-month follow-up. At6-month follow-up, 68% of patients reported complete

    resolution of their pain (p\ 0.007) and 87% had completeresolution of their movement limitations (p\ 0.004). Nopatients reported significant mesh sensation at their

    6-month follow-up visit.

    Discussion

    While continuing to confer the benefits of minimally

    invasive surgery to patients, the eTEP access VHR tech-

    nique offers use of retromuscular space and allows for

    complete exclusion of mesh from the peritoneal cavity,

    thus avoiding direct contact between mesh and visceral

    contents. Furthermore, penetrating transfascial fixation has

    been minimized as wide-size mesh is sandwiched in

    between posterior and anterior layers of the abdominal

    wall. Primary defect closure has been routinely performed

    in this case series and has been facilitated by the medial

    trocar placement achieved with eTEP access.

    As anticipated, our study supports the protective role

    of the minimally invasive techniques as compared to

    operative morbidity seen with traditional open hernia

    repair. It is difficult to determine the actual number of

    cases that would have undergone open Rives Stoppa or

    TAR procedures in the past prior to eTEP access

    implementation in our practice. Specifically considering

    that the average width of our eTEP access TAR cases

    Table 3 RS and TAR

    Variable eTEP approach

    RS mean defect width (cm) 6.2 ± 3.7

    RS mean defect area (cm2) 70.1 ± 43.3

    TAR mean defect width (cm) 11.1 ± 7.6

    TAR mean defect area (cm2) 205.3 ± 164.6

    Mean LOS (days)—RS 1.0 ± 0.7

    Mean LOS (days)—TAR 2.7 ± 1.3

    RS Rives Stoppa, TAR transversus abdominis release, LOS length of

    stay

    Table 4 Complications

    Variable eTEP approach

    Wound-related complications n = 3 (3.8%)

    Seroma 2.5%

    Wound dehiscence 1.3%

    Surgical site infection 0.0%

    Hematoma 0.0%

    Deep abscess 0.0%

    Non-wound-related complications n = 0 (0%)

    Stroke 0.0%

    Pneumonia 0.0%

    UTI 0.0%

    Myocardial infarction 0.0%

    CHF 0.0%

    Intraoperative complications n = 2 (2.5%)

    30-day readmissions n = 0%

    Hernia recurrence n = 1 (1.3%)

    Table 5 Quality of Life survey information using the Carolina Comfort Scale

    Variable Before surgery % symptomatic at 1 month p value % symptomatic at 6 months p value

    N 41 (51.9%) 38 (48.1%) 16 (20.3%)

    Sensation of mesh –

    Pain 58.5% 23.7% 0.002 18.0% 0.007

    Movement limitation 46.3% 15.8% 0.004 6.3% 0.004

    1530 Surg Endosc (2018) 32:1525–1532

    123

  • was 11.7 cm, historically in this subgroup we would have

    reconstructed the linea alba via an open approach. Studies

    from other institutions report complication rates of

    20–30% after open AWR surgery [15, 16]; these findings

    have been confirmed at our center as well [17]. These

    invasive methods would translate to greater LOS and data

    from our institutions show open AWR patients spent a

    mean of 5 days in the hospital [17]. Several other large

    series show hospital length of stay for complex open

    ventral and incisional hernia repair patients ranging from

    5 to 10 days [18, 19]. The mean LOS for our eTEP

    patients was 1.8 days; when broken down by Rives

    Stoppa technique and TAR, our mean LOS was 1.0 and

    2.7 days, respectively, highlighting benefits for patients

    and the current cost-containment environment of health

    care for both of these procedures.

    Chronic pain and movement limitations are among the

    main complaints of hernia patients, promoting a cycle of

    inactivity, weight gain, and progressive loss of function.

    Six months after eTEP access VHR, most patients in our

    series showed significant relief from pain and movement

    limitation. Utilizing the same methodology, Colavita et al.

    have previously used CCS to report on QOL outcomes in

    patients that underwent ventral hernia repairs. The mean

    defect area and percent of patients with prior ventral hernia

    repair in their study were 89.4 cm2 and 21.7%, respec-

    tively. They reported that 57% of their patients had clini-

    cally significant pain prior to surgery, and at 4 weeks after

    LVHR, 56% of patients continued to report clinically sig-

    nificant symptoms. After 6 months of follow-up, that

    number went down to 25% [13]. In our cohort of patients,

    we observed similar degree of symptomatic patients in the

    preoperative setting, with 58.5% of patients having sig-

    nificant pain prior to surgical intervention. Following our

    cohort at 1 months and at 6 months, only 23.7 and 18.8%

    of patients, respectively, reported some pain symptoms.

    Although there is lack of direct patient comparison

    between the two study groups, we believe that we are

    observing less pain in the immediate postoperative period

    because mesh placement in the retromuscular space has

    enabled us to minimize the aggressive use of penetrating

    fixation. The relationship of penetrating fixation to chronic

    pain is well established [20–24]. When performing a

    retromuscular repair, Weltz et al. have recently described

    that transfascial fixation of mesh is 12-fold more likely to

    result in chronic pain at 6 months as compared to non-

    penetrating fixation with Tisseel fibrin glue [17]. Perhaps

    one of the biggest benefits of the eTEP access approach is

    the use of retromuscular space for placement of large

    macroporous mesh, thus nearly eliminating penetrating

    fixation in our cohort.

    The multi-institutional nature of our study supports that

    eTEP access VHR is a reproducible technique among

    experienced laparoscopic surgeons. As discussed in our

    methodology, five centers participated in this study from

    four different continents across the globe. The sharing of

    expert insight, imaging, and educational videos among

    centers has afforded a unique partnership that has aimed to

    not only rapidly advance the science and surgical care of

    complex hernia patients but also to improve their out-

    comes. While these observations are experiential not

    experimental at this point, they do offer potential pathways

    to expedite safe technical adoption of this approach.

    There are several important limitations to this study

    that bear emphasis. This is a retrospective review of 79

    patients that have undergone an eTEP access laparoscopic

    approach to AWR. This review did not perform any direct

    comparison of our eTEP cohort to our historic laparo-

    scopic VHR or open AWR patients. Thus, it is difficult to

    determine how many of the patients in our cohort would

    have undergone lap VHR or open approach if operated

    prior to introduction of eTEP access technique to our

    practice. Also consideration should be given that not all

    complex hernia cases can be addressed with eTEP access

    technique and certainly as described in our methods sec-

    tion some complex cases are still addressed via open

    approach. Thus, based on this early experience it is dif-

    ficult to truly scale the importance of this minimally

    invasive reconstructive approach. In addition, inherent to

    all studies that rely on any retrospective data collection is

    the possibility of recall bias. We attempted to counter this

    by collecting all of our CCS scores prospectively at

    specific time intervals to gain a more comprehensive

    perspective of outcomes for our patients. However,

    another limitation of our study was that only one center

    (AAMC) participated in QOL assessment which limits the

    generalizability of outcomes in this study. Finally, this

    case series is work representative of surgeons with

    advanced laparoscopic training and results may not be

    translatable to the general population of hernia surgeons.

    To determine the true applicability, reproducibility, and

    benefits of eTEP access in AWR patients, randomized

    multicenter prospective studies are needed.

    Conclusions

    Our initial multicenter evaluation of the eTEP access

    technique for ventral and incisional hernias demonstrated

    the approach to be safe and feasible when performed in

    ventral and incisional hernia cases. This novel approach

    offers an extraperitoneal suture closure of defects, wide

    sublay mesh coverage with minimal penetrating fixation

    during the repair of ventral and incisional hernias. While

    long-term follow-up is needed to confirm applicability and

    efficacy of eTEP access VHR, we believe this approach

    Surg Endosc (2018) 32:1525–1532 1531

    123

  • offers an important addition to armamentarium of hernia

    surgeons.

    Financial support No financial support was received for this study

    Compliance with ethical standards

    Disclosures Dr. Belyansky is a consultant for Lifecell corporation,Intuitive Surgical, Covidien Medtronic, and Bard Davol. Dr. Daes is a

    consultant for Winner, Medtronic, and Bard. Dr. Novitsky is a con-

    sultant for Cooper Surgical, Intuitive Surgical, and Bard. Dr. Park is a

    consultant for Stryker. Dr’s Zahiri, Weltz, Sibia, Balasubramanian,

    and Radu declare that they have no relevant conflicts of interest or

    financial ties to disclose.

    Ethical approval All authors certify that they accept responsibilityas an author and have contributed to the concept, data gathering,

    analysis, manuscript drafting, and give their final approval.

    References

    1. LeBlanc KA, Booth WV (1993) Laparoscopic repair of incisional

    abdominal hernias using expanded polytetrafluoroethylene: pre-

    liminary findings. Surg Laparosc Endosc 3:39–41

    2. Heniford BT, Park A, Ramshaw BJ et al (2003) Laparoscopic

    repair of ventral hernias: nine years’ experience with 850 con-

    secutive hernias. Ann Surg 238:391–399

    3. Orenstein SB, Dumeer JL, Monteagudo J et al (2011) Outcomes

    of laparoscopic ventral hernia repair with routine defect closure

    using ‘‘shoelacing’’ technique. Surg Endosc 25(5):1452–1457

    4. Earle D, Roth JS, Saber A et al (2016) SAGES guidelines for

    laparoscopic ventral hernia repair. SAGES Guidelines Commit-

    tee. Surg Endosc 30(8):3163–3183

    5. Tandon A, Pathak S, Lyons NJ et al (2016) Meta-analysis of

    closure of the fascial defect during laparoscopic incisional and

    ventral hernia repair. Br J Surg 103(12):1598–1607. doi:10.1002/

    bjs.10268

    6. Wake BL, McCormack K, Fraser C et al (2005) Transabdominal

    preperitoneal (TAPP) vs totally extraperitoneal (TEP) laparo-

    scopic techniques for inguinal hernia repair. Cochrane Database

    Syst Rev. doi:10.1089/lap.2008.0212

    7. Leibl BJ, Jager C, Kraft B et al (2005) Laparoscopic hernia repair

    TAPP or/and TEP? Langenbecks Arch Surg 390:77–82

    8. Prasad P, Tantia O, Patle NM (2011) Laparoscopic ventral hernia

    repair: a comparative study of transabdominal preperitoneal

    versus intraperitoneal onlay mesh repair. J Laparoendosc Adv

    Surg Tech A. 21(6):477–483

    9. Belyansky I, Zahiri HR, Park A (2016) Laparoscopic transversus

    abdominis release, a novel minimally invasive approach to

    complex abdominal wall reconstruction. Surg Innovation

    23(2):134–141

    10. Daes J (2012) The enhanced view–totally extraperitoneal tech-

    nique for repair of inguinal hernia. Surg Endosc 26(4):1187–1189

    11. Daes J (2016) The extended-view totally extraperitoneal e-TEP

    technique for inguinal hernia repair. In: Novitsky YW (ed) Hernia

    surgery, current principles. Springer, NewYork, pp 467–472

    12. Heniford BT, Walters AL, Lincourt AE et al (2008) Comparison

    of generic versus specific quality-of-life scales for mesh hernia

    repairs. J Am Coll Surg 206(4):638–644

    13. Colavita PD, Tsirline VB, Belyansky I et al (2012) Prospective,

    long-term comparison of quality of life in laparoscopic versus

    open ventral hernia repair. Ann Surg 256(5):714–722

    14. Novitsky YW, Elliott HL, Orenstein SB et al (2012) Transversus

    abdominis muscle release: a novel approach to posterior com-

    ponent separation during complex abdominal wall reconstruction.

    Am J Surg 204(5):709–716

    15. Novitsky YW, Fayezizadeh M, Majumder A et al (2016) Out-

    comes of Posterior Component Separation With Transversus

    Abdominis Muscle Release and Synthetic Mesh Sublay Rein-

    forcement. Ann Surg 264(2):226–232

    16. Berry MF, Paisley S, Low DW et al (2007) Repair of large

    complex recurrent incisional hernias with retromuscular mesh

    and panniculectomy. Am J Surg 194(2):199–204

    17. Weltz AS, Sibia US, Zahiri HR et al (2017) Operative outcomes

    after open abdominal wall reconstruction with retromuscular

    mesh fixation using fibrin glue versus transfascial sutures. Am

    Surg 8:503–515

    18. Novitsky YW, Porter JR, Rucho ZC et al (2006) Open preperi-

    toneal retrofascial mesh repair for multiply recurrent ventral

    incisional hernias. J Am Coll Surg 203:283–289

    19. Giurgius M, Bendure L, Davenport DL et al (2012) The endo-

    scopic component separation technique for hernia repair results in

    reduced morbidity compared to the open component separation

    technique. Hernia 16:47–51

    20. Iqbal CW, Pham TH, Joseph A et al (2007) Long-term outcome

    of 254 complex incisional hernia repairs using the modified

    Rives-Stoppa technique. World J Surg 31:2398–2404

    21. Hanna EM, Byrd JF, Moskowitz M et al (2014) Outcomes of a

    prospective multi-center trial of a second-generation composite

    mesh for open ventral hernia repair. Hernia 18(1):81–89

    22. Vermeulen J, Alwayn I, Stassen LP (2003) Prolonged abdominal

    wall pain caused by transfascial sutures used in the laparoscopic

    repair of incisional hernia. Surg Endosc 17(9):1497

    23. LeBlanc KA (2007) Laparoscopic incisional hernia repair: are

    transfascial sutures necessary? A review of the literature. Surg

    Endosc 21(4):508–513

    24. Brill JB, Turner PL (2011) Long-term outcomes with transfascial

    sutures versus tacks in laparoscopic ventral hernia repair: a

    review. Am Surg 77(4):458–465

    1532 Surg Endosc (2018) 32:1525–1532

    123

    http://dx.doi.org/10.1002/bjs.10268http://dx.doi.org/10.1002/bjs.10268http://dx.doi.org/10.1089/lap.2008.0212

    A novel approach using the enhanced-view totally extraperitoneal (eTEP) technique for laparoscopic retromuscular hernia repairAbstractBackgroundMethodsResultsConclusions

    MethodsStudy designPreoperative workup/patient selectionOperative techniqueUpper midline defectsLower midline defects

    ResultsDiscussionConclusionsReferences


Recommended