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Bio100 S12-01 Biology 100 A survey course of biology The syllabus What will we study? How to earn an “A” in this class The history of biology The scientific method (lab) The Life Sciences Department is part of the Mathematics and the Natural & Health Sciences Division We are in the Natural Sciences Building on the San Marcos campus of Palomar College, San Marcos, California 92069 Announcements Prerequisite verification is now being enforced for these courses at the time of registration: · · Zoology 200, Anatomy · Zoology 203, Physiology Students will be blocked from enrollment unless their computer records indicate successful completion of the prerequisite course work. Students who have completed prerequisite course work at another institution must provide transcript evidence to the Evaluations Office within the Admissions & Records Office. This must be done before attempting to enroll in the course, at least 2-3 days prior to their registration appointment date. “Prerequisite Evaluation Request” forms are available in the Evaluations Office, SSC-40. For more information, contact the Evaluations Office at 760-744-1150, x2165, or at [email protected] . Field Courses The Life Sciences Department offers three field courses each year: Catalina Island (spring break), Greater Yellowstone Ecosystem (summer), and Belize (winter break). Click on the graphics below for more information. Photo: Kristine Maloney Online Courses Biology 101, Dan Sourbeer, Instructor Biology 114, Dan Sourbeer, Instructor All Life Science Courses and Programs Staff - Anatomy; Field Course (Chair) - Physiology; A&P - Majors Biology; General Biology, Human Genetics; (on sabbatical for the fall 2010 term) Gene Gushansky - Anatomy; General Biology - General Biology; Molecules and Cells; Faculty advisor for the . Beth Pearson - Marine Biology; General Biology; Botany; Catalina and Belize Field Courses - Majors Biology; General Biology; Zoology; Ecosystem Biology; GYE Field Course - General Biology; Microbiology Faculty Emeritus - Majors Biology, General Biology, Zoology, Human Genetics, Founder of the . - Botany; proprietor of Wayne's Word, the best botany site on the Web. Adjunct Faculty for Fall 2010 Michael Burg - BIO 100: General Biology - ZOO 120: Animal Behavior - BIO 200 Foundations I (Majors Bio) - BIO 105: Biology with a Human Emphasis Bob Garrett - BIO 100: General Biology - ZOO 145: Anatomy and Physiology - BIO 100: General Biology - BIO 102: Molecules and Cells Tom Jensen - ZOO 120: Animal Behavior - BIO 100: General Biology - BIO 200 Foundations I (Majors Bio) - BIO 100: General Biology Michael Monahan - ZOO 145: Anatomy and Physiology Robert Mustard - BIO 201: Foundations II (Majors Bio) - BIO 100: General Biology - ZOO 145L: Anatomy and Physiology Lab Chris Tubbs - ZOO 120: Animal Behavior Gary Waayers - BIO 100: General Biology - BIO 100: General Biology Bio100 S12-01 http://www.palomar.edu/lifescience/ Bio100 S12-01 http://faculty.palomar.edu/wkloetzer/ Palomar College eServices | Blackboard | Directory | Contact | Safety Palomar Community College District 1140 West Mission Road, San Marcos, CA 92069-1487 Telephone: 1 760 744-1150 © 2010 Palomar Community College District. All rights reserved. Contact Information. Legal Notices. PCBbAp03 Change Text Size High Contrast Setting Username: Password: Login Have an account? Please enter your credentials and click the Login button below. Don't have an account? Please choose from the options below. View Course Catalog Preview as Guest System Announcements 2010 Course Sites Are Not Here (Thursday, December 16, 2010) This Palomar Blackboard system houses course sites beginning with the Spring 2011 term. If for some reason you need access to older course sites, please visit the Old Palomar Blackboard system. Bio100 S12-01 Bio100 S12-01 Sunday, January 15, 2012 Bio10 00 Cale endar (Palomar College) by Willi Date 17-Jan 19-Jan 24-Jan 26-Jan 31-Jan 2-Feb 7-Feb 9-Feb 14-Feb 16-Feb 21-Feb 23-Feb 28-Feb 1-Mar 6-Mar iam Kloe etzer, Ph.D. Lecture Lecture (10:15 - 11:35AM) Textbook Bio100 Notes Homework Test Lab (11:45AM - 2:35PM) Lab Quiz L01 Course overview; biology - past and present Ch 1 1. The Scientific Method L02 Chemistry 1 Ch 2 S02 1. The Scientific Method L03 Chemistry 2 2. Microscopy L04 Biochemistry 1 Ch 3 S04 2. Microscopy L05 Biochemistry 2 H1-3 Quiz 1 (L1-3) 3. Natural Selection LQuiz 1 L06 Cell biology Ch 4 S06 3. Natural Selection LQuiz 1 L07 Thermodynamics, enzymes and membranes Ch 5 S07 4. Diffusion, osmosis & dialysis L08 Cell metabolism and respiration Ch 6 S08 4. Diffusion, osmosis & dialysis L09 Photosynthesis Ch 7 S09 H4-6 Quiz 2 (L4-6) 5. Enzymes LQuiz 2 L10 Mitosis Ch 8 S10 5. Enzymes LQuiz 2 L11 Meiosis, Mendelian genetics 1 optional field trip? L12 Mendelian genetics 2 Ch 9 S12 optional field trip? L13 DNA replication, transcription, translation Ch 10 S13 H7-9 Quiz 3 (L7-9) 6. Photosynthesis & cell respiration LQuiz 3 L14 Regulation of gene expression, signaling Ch 11, 12 S14 6. Photosynthesis & cell respiration LQuiz 3 - - Exam 1 (L1-9) 7. Mitosis Bio100 S12-01 Quiz #1 (Jan 31) covers: Lectures L01 - L03 Textbook chapters 1, 2 Bio100 Notes S02 Homework H1 - 3 Quiz #2 (Feb 14) covers: Lectures L04 - 06 Textbook chapters 3, 4 Bio100 Notes S04, S06 Homework H4 - 6 Exam #1 (Mar 6) covers: Lectures L01 - 09 Textbook chapters 1 - 7 Bio100 Notes S02 - 09 Homework Lab quizzes 1 - 3 Quiz #3 (Feb 28) covers: Lectures L07 - 09 Textbook chapters 5 - 7 Bio100 Notes S07 - 09 Homework H7 - 9
Transcript

Bio100 S12-01

Biology 100A survey course of biology

• The syllabus

• What will we study?

• How to earn an “A” in this class

• The history of biology

•The scientific method (lab)

1/12/11 11:55 AMPalomar College Life Sciences Department

Page 1 of 2http://www.palomar.edu/lifescience/default.htm

The Life Sciences Department is part of the Mathematics and the

Natural & Health Sciences Division

We are in the Natural Sciences Building

on the San Marcos campus of Palomar College,San Marcos, California 92069

Announcements

Prerequisite verification is now being enforced for these courses at the time ofregistration:

· Microbiology 200, Fundamentals of Microbiology · Zoology 200, Anatomy· Zoology 203, Physiology

Students will be blocked from enrollment unless their computer records indicatesuccessful completion of the prerequisite course work.

Students who have completed prerequisite course work at another institutionmust provide transcript evidence to the Evaluations Office within the Admissions& Records Office. This must be done before attempting to enroll in the course, atleast 2-3 days prior to their registration appointment date. “Prerequisite EvaluationRequest” forms are available in the Evaluations Office, SSC-40.

For more information, contact the Evaluations Office at 760-744-1150, x2165, or [email protected].

Premed Club

Field Courses

The Life Sciences Department offers three field courses each year: Catalina Island (spring break), Greater Yellowstone Ecosystem (summer), and Belize

(winter break). Click on the graphics below for more information.

Photo: Kristine Maloney

Online Courses

Biology 101, Dan Sourbeer, Instructor

Biology 114, Dan Sourbeer, Instructor

All Life Science Courses and Programs (These are PDF files from the 2009-2010 Catalog)

Biology

Staff Full-Time Faculty Richard Abistegui-DuBois - Physiology; General Biology; Molecules and Cells

Gary Alderson - Microbiology

Carey Carpenter - Anatomy; GYE Field Course

Ralph Ferges (Chair) - Physiology; A&P Jim Gilardi - Majors Biology; General Biology, Human Genetics; (onsabbatical for the fall 2010 term) Gene Gushansky - Anatomy; General Biology

Kimberly Marshall - General Biology; Molecules and Cells; Faculty advisor forthe Premed Club. Beth Pearson - Marine Biology; General Biology; Botany; Catalina and BelizeField Courses

Dan Sourbeer - Majors Biology; General Biology; Zoology; EcosystemBiology; GYE Field Course

Lesley Blankenship-Williams - General Biology; Microbiology Faculty Emeritus

Bob Ebert - Majors Biology, General Biology, Zoology, Human Genetics,Founder of the Premed Club.

Wayne Armstrong - Botany; proprietor of Wayne's Word, the best botany siteon the Web.

Adjunct Faculty for Fall 2010

Michael Burg - BIO 100: General Biology Barbara Durrant - ZOO 120: Animal BehaviorBob Ebert - BIO 200 Foundations I (Majors Bio)Bill Gaarde - BIO 105: Biology with a Human EmphasisBob Garrett - BIO 100: General Biology Rafael Gutierrez - ZOO 145: Anatomy and PhysiologyJohn Hakanson - BIO 100: General BiologyStacy Hull - BIO 102: Molecules and CellsTom Jensen - ZOO 120: Animal Behavior Bill Kloetzer - BIO 100: General Biology Ron Langlois - BIO 200 Foundations I (Majors Bio)Dan MacNeil - BIO 100: General Biology Michael Monahan - ZOO 145: Anatomy and PhysiologyRobert Mustard - BIO 201: Foundations II (Majors Bio)Melinda Ricatelli - BIO 100: General Biology Elmar Schmid - ZOO 145L: Anatomy and Physiology LabChris Tubbs - ZOO 120: Animal BehaviorGary Waayers - BIO 100: General BiologyRobyn Waayers - BIO 100: General Biology

Academic Department Assistant

Karen Buehler

Bio100 S12-01

http://www.palomar.edu/lifescience/

Bio100 S12-01

http://faculty.palomar.edu/wkloetzer/

Palomar College eServices | Blackboard | Directory | Contact | Safety

Palomar Community College District 1140 West Mission Road, San Marcos, CA 92069-1487 Telephone: 1 760 744-1150

© 2010 Palomar Community College District. All rights reserved. Contact Information. Legal Notices. PCBbAp03

Change Text Size High Contrast Setting

Username:

Password:

Login

Have an account?

Please enter your credentials and click the Login button below.

Don't have an account?

Please choose from the options below.

View Course Catalog

Preview as Guest

System Announcements

2010 Course Sites Are Not Here (Thursday, December 16, 2010)This Palomar Blackboard system houses course sites beginning with the Spring 2011 term. If for some reason you need access to older course sites, please visit the Old PalomarBlackboard system.

Blackboard Learn https://learn.palomar.edu/

1 of 1 1/13/11 2:33 PM

Bio100 S12-01

Bio100 S12-01

Sunday, January 15, 2012

Bio100 Calendar (Palomar College)Bio100 Calendar (Palomar College)Bio100 Calendar (Palomar College)

by William Kloetzer, Ph.D.

Date

17-Jan

19-Jan

24-Jan

26-Jan

31-Jan

2-Feb

7-Feb

9-Feb

14-Feb

16-Feb

21-Feb

23-Feb

28-Feb

1-Mar

6-Mar

8-Mar

13-Mar

15-Mar

20-Mar

22-Mar

27-Mar

29-Mar

3-Apr

5-Apr

10-Apr

12-Apr

17-Apr

19-Apr

24-Apr

26-Apr

1-May

3-May

8-May

10-May

15-May

17-May

by William Kloetzer, Ph.D.by William Kloetzer, Ph.D.

Lecture Lecture (10:15 - 11:35AM) TextbookBio100 Notes Homework Test Lab (11:45AM - 2:35PM) Lab Quiz

L01 Course overview; biology - past and present Ch 1 1. The Scientific Method

L02 Chemistry 1 Ch 2 S02 1. The Scientific Method

L03 Chemistry 2 2. Microscopy

L04 Biochemistry 1 Ch 3 S04 2. Microscopy

L05 Biochemistry 2 H1-3 Quiz 1 (L1-3) 3. Natural Selection LQuiz 1

L06 Cell biology Ch 4 S06 3. Natural Selection LQuiz 1

L07 Thermodynamics, enzymes and membranes Ch 5 S07 4. Diffusion, osmosis & dialysis

L08 Cell metabolism and respiration Ch 6 S08 4. Diffusion, osmosis & dialysis

L09 Photosynthesis Ch 7 S09 H4-6 Quiz 2 (L4-6) 5. Enzymes LQuiz 2

L10 Mitosis Ch 8 S10 5. Enzymes LQuiz 2

L11 Meiosis, Mendelian genetics 1 optional field trip?

L12 Mendelian genetics 2 Ch 9 S12 optional field trip?

L13 DNA replication, transcription, translation Ch 10 S13 H7-9 Quiz 3 (L7-9) 6. Photosynthesis & cell respiration LQuiz 3

L14 Regulation of gene expression, signaling Ch 11, 12 S14 6. Photosynthesis & cell respiration LQuiz 3

- - Exam 1 (L1-9) 7. Mitosis

L15 Disease and biotechnology 7. Mitosis

L16 Histology and pathology H10-13 Quiz 4 (L10-13) 8. Meiosis LQuiz 4

L17 Immunology S17 8. Meiosis LQuiz 4

Spring Break

Spring Break

L18 Virology S18 9. Genetics

L19 EvolutionCh 13, 14,

15 9. Genetics

L20 Prokaryotes Ch 16 S20 H14-18 Quiz 5 (L14-18) 10. Biotechnology LQuiz 5

L21 Protists S21 10. Biotechnology LQuiz 5

L22 Fungi and plants 1 Ch 17 S22 11. Bacteriology

L23 Plants 2 11. Bacteriology

L24 Lower invertebrates Ch 18 S24 H19-23 Quiz 6 (L19-23) 12. Protists and fungi LQuiz 6

L25 Worms and mollusks S25 12. Protists and fungi LQuiz 6

- - Exam 2 (L10-23) 13. Life cycle of plants

L26 Arthropods; organ systems 1 S26 13. Life cycle of plants

L27 Marine chordates, ecology 1 and organ systems 2 S27 14. Plant anatomy

L28 Amphibians, reptiles and organ systems 3 Ch 19 14. Plant anatomy

L29 Birds, mammals and ecology 2 Ch 34, 35 S29 Quiz 7 (L24-28) 15. Animals LQuiz 7

L30 Conservation biology Ch 37, 38 S30 H29-30 15. Animals LQuiz 7

- Optional review session

- Cumulative final exam (9:45 - 11:35AM) Final Exam

Bio100 S12-01

Quiz #1 (Jan 31) covers:

• Lectures L01 - L03

• Textbook chapters 1, 2

• Bio100 Notes S02

• Homework H1 - 3

Quiz #2 (Feb 14) covers:

• Lectures L04 - 06

• Textbook chapters 3, 4

• Bio100 Notes S04, S06

• Homework H4 - 6

Exam #1 (Mar 6) covers:

• Lectures L01 - 09

• Textbook chapters 1 - 7

• Bio100 Notes S02 - 09

• Homework

• Lab quizzes 1 - 3

Quiz #3 (Feb 28) covers:

• Lectures L07 - 09

• Textbook chapters 5 - 7

• Bio100 Notes S07 - 09

• Homework H7 - 9

Bio100 S12-01

How to earn an “A” in this course (part 1)

Plan to study 3 - 6 hrs/week: (3 credit hrs)(1-2 hrs study per week/credit hr)

1) “Scan” the textbook and lab book chapters before class

2) Print lecture slides (6/page); bring these to class

3) Use your lecture slide print-outs for taking notes in class

4) Read “Bio100 Notes”

Bio100 S12-01

How to earn an “A” in this course (part 2)

Plan to study 3 - 6 hrs/week: (3 credit hrs)(1-2 hrs study per week/credit hr)

5) Individual study tips

- read the textbook carefully

- review your notes and slides

- make flash cards

6) Form a study group with one or several classmates

7) Turn in homework assignments on time

8) Attend every lecture and lab session

Bio100 S12-01

Tentative extra credit field trips

explore Carlsbad tide pools (-1.5’ on Wed Feb 22 at 2:18PM)

or

attend a San Diego Oceans Foundation lecture (TBD)

or

tour (for free!) the San Diego Safari Park (TBD)

Bio100 S12-01

What are we going to study?

Molecular and Cellular Biology

EUKARYOTIC CELL

Membrane

Cytoplasm

Organelles

Nucleus (contains DNA) 1 !m

PROKARYOTIC CELL

DNA (no nucleus)

Membrane

bacterial cellhuman cell

• Chemistry

• Biochemistry

• Organelle structure and function

• Cell division

• How plant and animal cells

obtain energy

Bio100 S12-01

mitochondrion

chloroplast

What are we going to study?

How plant and animal cells obtain and use energy

Bio100 S12-01

What are we going to study?

Molecular genetics and biotechnology

• How cells read the genome

• Inherited & acquired gene mutations

• Molecular basis of disease

• Therapeutic drug discovery

• Vaccine development

Sperm cell

Nucleicontaining

DNA

Fertilized eggwith DNA fromboth parents

Embyro’s cells with copies of inherited DNA

Offspring with traitsinherited fromboth parents

Egg cell

DNA

Cell

Nucleotide

ACTATA

CC

G

G

TA

TA

Nucleus

Bio100 S12-01

What are we going to study?

Organization of Living Things

Prokaryote cells

• are usually smaller than eukaryotic cells

• lack membrane-bound organelles

• lack a nucleus

Bacteria Archaea

Prokaryotes

Protists Fungi Plants Animals

Eukaryotes

Bio100 S12-01

1

2

3

3.1

3.2

3.3

3.4

Bio100 S12-01

What are we going to study?

Evolution of living things

Bio100 S12-01

What are we going to study?

Evolution of living things

Multicellularity

True tissues

Radial symmetry

1

Sponges Cnidarians

Bio100 S12-01

Kingdom Animalia

Coelom from digestive tube

Echinoderms Chordates

4

Bilateral symmetry

No body cavity

Body cavities

PseudocoelomTrue coelom

Coelom from cell masses

2

3

Flatworms Roundworms AnnelidsMollusks Arthropods

Bio100 S12-01

MoleculeDNA

AtomOxygen atom

• Cell biology

• Molecular biology

• Biochemistry

• Chemistry

CellHeart muscle cell

Organism Zebra

Organ systemCirculatory system

OrganHeart

TissueHeart muscle

tissue

• Anatomy

• Physiology

• Genetics

• Developmental biology

• Histology

CommunityAll organisms in savanna

PopulationHerd of zebras

• Wildlife biology

• Marine biology

Ecosystem African savanna

• Conservation biology

• Ecology

What are we going to study?

Bio100 S12-01

popular topics in biology

• new biotech treatments for disease

• anti-viral vaccines

• biofuels

• global threats to biological diversity• climate change

• pollution

• conservation• local (e.g., California Marine Protected Areas)

• world wide (e.g., Africa wildlife reserves)

Bio100 S12-01

The history of biology: distinguished scientists“All living organisms are composed of cells”

Robert Hooke (1635 - 1703)

• microscopy: author of Micrographia; first used "cell" in biology

• Hooke’s law of elasticity(the watch spring)

• astronomy

• architect

Bio100 S12-01

The history of biology: distinguished scientists“All living organisms are composed of cells”

Anton van Leeuwenhoek (1632 - 1723)

• Described algae, bacteria and protozoa using a simple microscope

Bio100 S12-01

Views through a simple microscope as seenby Anton Van Leeuwenhoek

http://www.sciences.demon.co.uk/wav-spf.htm

spiral bacteria microspora cells (cyanophytes)

truffle human sperm

Bio100 S12-01

The history of biology: distinguished scientists“Taxonomy, evolution and heredity”

Carolus Linnaeus (Carl von Linné; 1707 - 1778)

• The binomial system of naming organisms

Kingdom (e.g., Animalia)

Phylum (e.g., Chordata)

Class (e.g., Mammals)

Order (e.g., Primates)

Family (e.g., Hominoidea)

Genus (e.g., Homo)

Species (e.g., H. sapiens)

Bio100 S12-01

The history of biology: distinguished scientists“Taxonomy, evolution and heredity”

Jean-Baptiste Lamarck (1744 - 1829)

• Pre-Darwin ideas on evolution:

- use or disuse causes structures to enlarge or shrink over

- several generations

- such changes are heritable

• Fossil evidence suggests that mollusks change over time

Bio100 S12-01

The history of biology: distinguished scientists“Taxonomy, evolution and heredity”

Charles Darwin (1809 - 1884)

• "On The Origin Of Species", 1859

Modern species evolved from ancestral forms

• Natural selection (the struggle for existence) is the principle mechanism for evolution

Bio100 S12-01

The history of biology: distinguished scientists“Taxonomy, evolution and heredity”

Gregor Mendel (1822 - 1884)

• Proposes basic laws of genetics based on propagation experiments with garden

pea plants

Bio100 S12-01

The history of biology: distinguished scientists“20th century scientists and biology milestones”

Jonas Salk (1914 - 1995)

• Develops a vaccine that protects against polio virus infection

• The Salk Institute

"Hope lies in dreams, in imagination and in the courage of

those who dare to make dreams into reality.”Bio100 S12-01

Bio100 S12-01

Distinguished 21st century scientists

Syndey Brenner, Robert Horvitz & John Sulston

• 2002 Nobel prize: for their discoveries concerning

“genetic regulation of organ development and

programmed cell death pathway”

• scientist at the Salk Institute

Bio100 S12-01

Distinguished 21st century scientists

Syndey Brenner - Salk Institute

Andrew Fire & Craig Mello

• 2006 Nobel prize: gene silencing by interference RNA

Bio100 S12-01

Distinguished 21st century scientists

Syndey Brenner - Salk Institute

Andrew Fire & Craig Mello

Mario Capecchi, Martin Evans & Oliver Smithies

Elizabeth Blackburn, Carol Greider and Jack Szostak

• 2009 Nobel prize - for the discovery of how chromosomes are

protected by telomeres and the enzyme telomerase

Bio100 S12-01

NEXT: Chemistry (L02)

• metric units

• elements, atoms, orbitals, the periodic table

• compounds, molecules, molecular bonds

• water: the ideal solvent

• pH and buffers

Bio100 S12-01

DEFINITIONS

Biology is the scientific study of life

Hypothesis: A tentative answer to a well-framed question

or an explanation for an observed phenomenon.

Theory: An explanation that is broad in scope, generates

new hypotheses, and is supported by a large body of

evidence.Bio100 S12-01

The process of science

Scientific method: A collection of techniques for

investigating phenomena and acquiring knowledge. It

is based on observable, empirical, measurable

evidence, and is subject to laws of reasoning.

Discovery-based science

Hypothesis-based science

Bio100 S12-01

Discovery-based science: a scientific method that emphasizes analysis of large volumes of experimental data with the goal of finding new patterns or correlations, leading to hypothesis formation and other scientific methodologies (a.k.a. data mining)

Hypothesis-based science: a tentative answer to a well-framed question or explanation for an observed phenomenon

Bio100 S12-01

Inductive reasoning: Generalizations based on a

large number of specif ic observations

(discovery-based science)

Deductive reasoning: Results predicted from a

generalization (hypothesis-based science)

Bio100 S12-01

Deductive reasoningObservations

Questions

Hypothesis # 1: Dead batteries

Prediction: Replacing batteries will fix problem

Test prediction

Test falsifies hypothesis

Hypothesis # 2: Burnt-out bulb

Prediction: Replacing bulb will fix problem

Test does not falsify hypothesis

Test prediction


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