Bio100 S12-01
Biology 100A survey course of biology
• The syllabus
• What will we study?
• How to earn an “A” in this class
• The history of biology
•The scientific method (lab)
1/12/11 11:55 AMPalomar College Life Sciences Department
Page 1 of 2http://www.palomar.edu/lifescience/default.htm
The Life Sciences Department is part of the Mathematics and the
Natural & Health Sciences Division
We are in the Natural Sciences Building
on the San Marcos campus of Palomar College,San Marcos, California 92069
Announcements
Prerequisite verification is now being enforced for these courses at the time ofregistration:
· Microbiology 200, Fundamentals of Microbiology · Zoology 200, Anatomy· Zoology 203, Physiology
Students will be blocked from enrollment unless their computer records indicatesuccessful completion of the prerequisite course work.
Students who have completed prerequisite course work at another institutionmust provide transcript evidence to the Evaluations Office within the Admissions& Records Office. This must be done before attempting to enroll in the course, atleast 2-3 days prior to their registration appointment date. “Prerequisite EvaluationRequest” forms are available in the Evaluations Office, SSC-40.
For more information, contact the Evaluations Office at 760-744-1150, x2165, or [email protected].
Premed Club
Field Courses
The Life Sciences Department offers three field courses each year: Catalina Island (spring break), Greater Yellowstone Ecosystem (summer), and Belize
(winter break). Click on the graphics below for more information.
Photo: Kristine Maloney
Online Courses
Biology 101, Dan Sourbeer, Instructor
Biology 114, Dan Sourbeer, Instructor
All Life Science Courses and Programs (These are PDF files from the 2009-2010 Catalog)
Biology
Staff Full-Time Faculty Richard Abistegui-DuBois - Physiology; General Biology; Molecules and Cells
Gary Alderson - Microbiology
Carey Carpenter - Anatomy; GYE Field Course
Ralph Ferges (Chair) - Physiology; A&P Jim Gilardi - Majors Biology; General Biology, Human Genetics; (onsabbatical for the fall 2010 term) Gene Gushansky - Anatomy; General Biology
Kimberly Marshall - General Biology; Molecules and Cells; Faculty advisor forthe Premed Club. Beth Pearson - Marine Biology; General Biology; Botany; Catalina and BelizeField Courses
Dan Sourbeer - Majors Biology; General Biology; Zoology; EcosystemBiology; GYE Field Course
Lesley Blankenship-Williams - General Biology; Microbiology Faculty Emeritus
Bob Ebert - Majors Biology, General Biology, Zoology, Human Genetics,Founder of the Premed Club.
Wayne Armstrong - Botany; proprietor of Wayne's Word, the best botany siteon the Web.
Adjunct Faculty for Fall 2010
Michael Burg - BIO 100: General Biology Barbara Durrant - ZOO 120: Animal BehaviorBob Ebert - BIO 200 Foundations I (Majors Bio)Bill Gaarde - BIO 105: Biology with a Human EmphasisBob Garrett - BIO 100: General Biology Rafael Gutierrez - ZOO 145: Anatomy and PhysiologyJohn Hakanson - BIO 100: General BiologyStacy Hull - BIO 102: Molecules and CellsTom Jensen - ZOO 120: Animal Behavior Bill Kloetzer - BIO 100: General Biology Ron Langlois - BIO 200 Foundations I (Majors Bio)Dan MacNeil - BIO 100: General Biology Michael Monahan - ZOO 145: Anatomy and PhysiologyRobert Mustard - BIO 201: Foundations II (Majors Bio)Melinda Ricatelli - BIO 100: General Biology Elmar Schmid - ZOO 145L: Anatomy and Physiology LabChris Tubbs - ZOO 120: Animal BehaviorGary Waayers - BIO 100: General BiologyRobyn Waayers - BIO 100: General Biology
Academic Department Assistant
Karen Buehler
Bio100 S12-01
http://www.palomar.edu/lifescience/
Bio100 S12-01
http://faculty.palomar.edu/wkloetzer/
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2010 Course Sites Are Not Here (Thursday, December 16, 2010)This Palomar Blackboard system houses course sites beginning with the Spring 2011 term. If for some reason you need access to older course sites, please visit the Old PalomarBlackboard system.
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1 of 1 1/13/11 2:33 PM
Bio100 S12-01
Bio100 S12-01
Sunday, January 15, 2012
Bio100 Calendar (Palomar College)Bio100 Calendar (Palomar College)Bio100 Calendar (Palomar College)
by William Kloetzer, Ph.D.
Date
17-Jan
19-Jan
24-Jan
26-Jan
31-Jan
2-Feb
7-Feb
9-Feb
14-Feb
16-Feb
21-Feb
23-Feb
28-Feb
1-Mar
6-Mar
8-Mar
13-Mar
15-Mar
20-Mar
22-Mar
27-Mar
29-Mar
3-Apr
5-Apr
10-Apr
12-Apr
17-Apr
19-Apr
24-Apr
26-Apr
1-May
3-May
8-May
10-May
15-May
17-May
by William Kloetzer, Ph.D.by William Kloetzer, Ph.D.
Lecture Lecture (10:15 - 11:35AM) TextbookBio100 Notes Homework Test Lab (11:45AM - 2:35PM) Lab Quiz
L01 Course overview; biology - past and present Ch 1 1. The Scientific Method
L02 Chemistry 1 Ch 2 S02 1. The Scientific Method
L03 Chemistry 2 2. Microscopy
L04 Biochemistry 1 Ch 3 S04 2. Microscopy
L05 Biochemistry 2 H1-3 Quiz 1 (L1-3) 3. Natural Selection LQuiz 1
L06 Cell biology Ch 4 S06 3. Natural Selection LQuiz 1
L07 Thermodynamics, enzymes and membranes Ch 5 S07 4. Diffusion, osmosis & dialysis
L08 Cell metabolism and respiration Ch 6 S08 4. Diffusion, osmosis & dialysis
L09 Photosynthesis Ch 7 S09 H4-6 Quiz 2 (L4-6) 5. Enzymes LQuiz 2
L10 Mitosis Ch 8 S10 5. Enzymes LQuiz 2
L11 Meiosis, Mendelian genetics 1 optional field trip?
L12 Mendelian genetics 2 Ch 9 S12 optional field trip?
L13 DNA replication, transcription, translation Ch 10 S13 H7-9 Quiz 3 (L7-9) 6. Photosynthesis & cell respiration LQuiz 3
L14 Regulation of gene expression, signaling Ch 11, 12 S14 6. Photosynthesis & cell respiration LQuiz 3
- - Exam 1 (L1-9) 7. Mitosis
L15 Disease and biotechnology 7. Mitosis
L16 Histology and pathology H10-13 Quiz 4 (L10-13) 8. Meiosis LQuiz 4
L17 Immunology S17 8. Meiosis LQuiz 4
Spring Break
Spring Break
L18 Virology S18 9. Genetics
L19 EvolutionCh 13, 14,
15 9. Genetics
L20 Prokaryotes Ch 16 S20 H14-18 Quiz 5 (L14-18) 10. Biotechnology LQuiz 5
L21 Protists S21 10. Biotechnology LQuiz 5
L22 Fungi and plants 1 Ch 17 S22 11. Bacteriology
L23 Plants 2 11. Bacteriology
L24 Lower invertebrates Ch 18 S24 H19-23 Quiz 6 (L19-23) 12. Protists and fungi LQuiz 6
L25 Worms and mollusks S25 12. Protists and fungi LQuiz 6
- - Exam 2 (L10-23) 13. Life cycle of plants
L26 Arthropods; organ systems 1 S26 13. Life cycle of plants
L27 Marine chordates, ecology 1 and organ systems 2 S27 14. Plant anatomy
L28 Amphibians, reptiles and organ systems 3 Ch 19 14. Plant anatomy
L29 Birds, mammals and ecology 2 Ch 34, 35 S29 Quiz 7 (L24-28) 15. Animals LQuiz 7
L30 Conservation biology Ch 37, 38 S30 H29-30 15. Animals LQuiz 7
- Optional review session
- Cumulative final exam (9:45 - 11:35AM) Final Exam
Bio100 S12-01
Quiz #1 (Jan 31) covers:
• Lectures L01 - L03
• Textbook chapters 1, 2
• Bio100 Notes S02
• Homework H1 - 3
Quiz #2 (Feb 14) covers:
• Lectures L04 - 06
• Textbook chapters 3, 4
• Bio100 Notes S04, S06
• Homework H4 - 6
Exam #1 (Mar 6) covers:
• Lectures L01 - 09
• Textbook chapters 1 - 7
• Bio100 Notes S02 - 09
• Homework
• Lab quizzes 1 - 3
Quiz #3 (Feb 28) covers:
• Lectures L07 - 09
• Textbook chapters 5 - 7
• Bio100 Notes S07 - 09
• Homework H7 - 9
Bio100 S12-01
How to earn an “A” in this course (part 1)
Plan to study 3 - 6 hrs/week: (3 credit hrs)(1-2 hrs study per week/credit hr)
1) “Scan” the textbook and lab book chapters before class
2) Print lecture slides (6/page); bring these to class
3) Use your lecture slide print-outs for taking notes in class
4) Read “Bio100 Notes”
Bio100 S12-01
How to earn an “A” in this course (part 2)
Plan to study 3 - 6 hrs/week: (3 credit hrs)(1-2 hrs study per week/credit hr)
5) Individual study tips
- read the textbook carefully
- review your notes and slides
- make flash cards
6) Form a study group with one or several classmates
7) Turn in homework assignments on time
8) Attend every lecture and lab session
Bio100 S12-01
Tentative extra credit field trips
explore Carlsbad tide pools (-1.5’ on Wed Feb 22 at 2:18PM)
or
attend a San Diego Oceans Foundation lecture (TBD)
or
tour (for free!) the San Diego Safari Park (TBD)
Bio100 S12-01
What are we going to study?
Molecular and Cellular Biology
EUKARYOTIC CELL
Membrane
Cytoplasm
Organelles
Nucleus (contains DNA) 1 !m
PROKARYOTIC CELL
DNA (no nucleus)
Membrane
bacterial cellhuman cell
• Chemistry
• Biochemistry
• Organelle structure and function
• Cell division
• How plant and animal cells
obtain energy
Bio100 S12-01
mitochondrion
chloroplast
What are we going to study?
How plant and animal cells obtain and use energy
Bio100 S12-01
What are we going to study?
Molecular genetics and biotechnology
• How cells read the genome
• Inherited & acquired gene mutations
• Molecular basis of disease
• Therapeutic drug discovery
• Vaccine development
Sperm cell
Nucleicontaining
DNA
Fertilized eggwith DNA fromboth parents
Embyro’s cells with copies of inherited DNA
Offspring with traitsinherited fromboth parents
Egg cell
DNA
Cell
Nucleotide
ACTATA
CC
G
G
TA
TA
Nucleus
Bio100 S12-01
What are we going to study?
Organization of Living Things
Prokaryote cells
• are usually smaller than eukaryotic cells
• lack membrane-bound organelles
• lack a nucleus
Bacteria Archaea
Prokaryotes
Protists Fungi Plants Animals
Eukaryotes
Bio100 S12-01
1
2
3
3.1
3.2
3.3
3.4
Bio100 S12-01
What are we going to study?
Evolution of living things
Bio100 S12-01
What are we going to study?
Evolution of living things
Multicellularity
True tissues
Radial symmetry
1
Sponges Cnidarians
Bio100 S12-01
Kingdom Animalia
Coelom from digestive tube
Echinoderms Chordates
4
Bilateral symmetry
No body cavity
Body cavities
PseudocoelomTrue coelom
Coelom from cell masses
2
3
Flatworms Roundworms AnnelidsMollusks Arthropods
Bio100 S12-01
MoleculeDNA
AtomOxygen atom
• Cell biology
• Molecular biology
• Biochemistry
• Chemistry
CellHeart muscle cell
Organism Zebra
Organ systemCirculatory system
OrganHeart
TissueHeart muscle
tissue
• Anatomy
• Physiology
• Genetics
• Developmental biology
• Histology
CommunityAll organisms in savanna
PopulationHerd of zebras
• Wildlife biology
• Marine biology
Ecosystem African savanna
• Conservation biology
• Ecology
What are we going to study?
Bio100 S12-01
popular topics in biology
• new biotech treatments for disease
• anti-viral vaccines
• biofuels
• global threats to biological diversity• climate change
• pollution
• conservation• local (e.g., California Marine Protected Areas)
• world wide (e.g., Africa wildlife reserves)
Bio100 S12-01
The history of biology: distinguished scientists“All living organisms are composed of cells”
Robert Hooke (1635 - 1703)
• microscopy: author of Micrographia; first used "cell" in biology
• Hooke’s law of elasticity(the watch spring)
• astronomy
• architect
Bio100 S12-01
The history of biology: distinguished scientists“All living organisms are composed of cells”
Anton van Leeuwenhoek (1632 - 1723)
• Described algae, bacteria and protozoa using a simple microscope
Bio100 S12-01
Views through a simple microscope as seenby Anton Van Leeuwenhoek
http://www.sciences.demon.co.uk/wav-spf.htm
spiral bacteria microspora cells (cyanophytes)
truffle human sperm
Bio100 S12-01
The history of biology: distinguished scientists“Taxonomy, evolution and heredity”
Carolus Linnaeus (Carl von Linné; 1707 - 1778)
• The binomial system of naming organisms
Kingdom (e.g., Animalia)
Phylum (e.g., Chordata)
Class (e.g., Mammals)
Order (e.g., Primates)
Family (e.g., Hominoidea)
Genus (e.g., Homo)
Species (e.g., H. sapiens)
Bio100 S12-01
The history of biology: distinguished scientists“Taxonomy, evolution and heredity”
Jean-Baptiste Lamarck (1744 - 1829)
• Pre-Darwin ideas on evolution:
- use or disuse causes structures to enlarge or shrink over
- several generations
- such changes are heritable
• Fossil evidence suggests that mollusks change over time
Bio100 S12-01
The history of biology: distinguished scientists“Taxonomy, evolution and heredity”
Charles Darwin (1809 - 1884)
• "On The Origin Of Species", 1859
Modern species evolved from ancestral forms
• Natural selection (the struggle for existence) is the principle mechanism for evolution
Bio100 S12-01
The history of biology: distinguished scientists“Taxonomy, evolution and heredity”
Gregor Mendel (1822 - 1884)
• Proposes basic laws of genetics based on propagation experiments with garden
pea plants
Bio100 S12-01
The history of biology: distinguished scientists“20th century scientists and biology milestones”
Jonas Salk (1914 - 1995)
• Develops a vaccine that protects against polio virus infection
• The Salk Institute
"Hope lies in dreams, in imagination and in the courage of
those who dare to make dreams into reality.”Bio100 S12-01
Bio100 S12-01
Distinguished 21st century scientists
Syndey Brenner, Robert Horvitz & John Sulston
• 2002 Nobel prize: for their discoveries concerning
“genetic regulation of organ development and
programmed cell death pathway”
• scientist at the Salk Institute
Bio100 S12-01
Distinguished 21st century scientists
Syndey Brenner - Salk Institute
Andrew Fire & Craig Mello
• 2006 Nobel prize: gene silencing by interference RNA
Bio100 S12-01
Distinguished 21st century scientists
Syndey Brenner - Salk Institute
Andrew Fire & Craig Mello
Mario Capecchi, Martin Evans & Oliver Smithies
Elizabeth Blackburn, Carol Greider and Jack Szostak
• 2009 Nobel prize - for the discovery of how chromosomes are
protected by telomeres and the enzyme telomerase
Bio100 S12-01
NEXT: Chemistry (L02)
• metric units
• elements, atoms, orbitals, the periodic table
• compounds, molecules, molecular bonds
• water: the ideal solvent
• pH and buffers
Bio100 S12-01
DEFINITIONS
Biology is the scientific study of life
Hypothesis: A tentative answer to a well-framed question
or an explanation for an observed phenomenon.
Theory: An explanation that is broad in scope, generates
new hypotheses, and is supported by a large body of
evidence.Bio100 S12-01
The process of science
Scientific method: A collection of techniques for
investigating phenomena and acquiring knowledge. It
is based on observable, empirical, measurable
evidence, and is subject to laws of reasoning.
Discovery-based science
Hypothesis-based science
Bio100 S12-01
Discovery-based science: a scientific method that emphasizes analysis of large volumes of experimental data with the goal of finding new patterns or correlations, leading to hypothesis formation and other scientific methodologies (a.k.a. data mining)
Hypothesis-based science: a tentative answer to a well-framed question or explanation for an observed phenomenon
Bio100 S12-01
Inductive reasoning: Generalizations based on a
large number of specif ic observations
(discovery-based science)
Deductive reasoning: Results predicted from a
generalization (hypothesis-based science)
Bio100 S12-01
Deductive reasoningObservations
Questions
Hypothesis # 1: Dead batteries
Prediction: Replacing batteries will fix problem
Test prediction
Test falsifies hypothesis
Hypothesis # 2: Burnt-out bulb
Prediction: Replacing bulb will fix problem
Test does not falsify hypothesis
Test prediction