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Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination...

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Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang Wang, Yinwei Ho, Tinisha McDonald, Tessa L. Holyoake, WenYong Chen, Ravi Bhatia Cancer Cell Volume 21, Issue 2, Pages 266-281 (February 2012) DOI: 10.1016/j.ccr.2011.12.020 Copyright © 2012 Elsevier Inc. Terms and Conditions

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Page 1: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib

Ling Li, Lisheng Wang, Liang Li, Zhiqiang Wang, Yinwei Ho, Tinisha McDonald, Tessa L. Holyoake, WenYong Chen, Ravi Bhatia

Cancer Cell Volume 21, Issue 2, Pages 266-281 (February 2012)

DOI: 10.1016/j.ccr.2011.12.020

Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

Page 2: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Figure 1

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

Page 3: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Figure 2

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

Page 4: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Figure 3

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

Page 5: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Figure 4

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

Page 6: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Figure 5

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

Page 7: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Figure 6

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

Page 8: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Figure 7

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

Page 9: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Figure 8

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

Page 10: Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib Ling Li, Lisheng Wang, Liang Li, Zhiqiang.

Cancer Cell 2012 21, 266-281DOI: (10.1016/j.ccr.2011.12.020) Copyright © 2012 Elsevier Inc. Terms and Conditions

http://www.elsevier.com/termsandconditions

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