8
ADULT OXYGENATORS CATALOGUE
ADULT OXYGENATORSCATALOGUE
Clinical flexibility
Optimized priming
High performance gas exchange
Low contact surface
Low GME activity
Easy to set up and debubble
A solution for every need
BLOOD\BODY FLUID CONTACT LAYER
ALKALINE CHAINS SPREAD ACROSS THE SURFACE YELDING A STABLE COATING THROUGH HYDROPHOBIC INTERACTIONS
LAYER OF HYDRATATION AROUND PC - WITH A COATED SUBSTRATETHE BLOOD THEREFORE “SEES” A LAYER OF WATER
ZWITTERIONIC PC GROUPS EXPRESSED OUTWARDS FROM THE SURFACE
FOREIGN SURFACE
FOREIGN SURFACE
PHOSPHORYLCHOLINE COATING
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THE pATH Of biOCOMpATibiLiTy
phosphorylcoline or pC is the predominant lipid headgroup found in the outer layer of cell membranes. pC has a natural affinity for water and binds water tightly around itself. As a result, the outer layer of the cell membrane does not promote clot formation (thrombosis).
•lowthrombogenicpotential•lowinflammatoryresponse•stable•resistanttobacterialadhesion•resistanttoproteindeposition
OXyGENATOR MODULE TECHNiCAL fEATURES
cardioplegiablood outlet
arterialblood outlet
purgingline
H.E. water in/out
venous blood inlet
ALONE OXYGENATOR MODULE TECHNICAL CHARACTERISTICSPriming volume: 190 mlContact surface area: 1,35 m2
Max blood flow rate: 7,0 l/minInnovative Heat Exchanger Heat Exchanger surface area: 0.08 m2
H.E. Performance Factor η = 0.64 (@ 4 l/min)Coating: PC phosphorylcholine
AMG OXYGENATOR MODULE TECHNICAL CHARACTERISTICSPriming volume: 220 mlContact surface area: 1,81 m2
Max blood flow rate: 8,0 l/minInnovative Heat Exchanger Heat Exchanger surface area: 0.08 m2
H.E. Performance Factor: η = 0.64 (@ 4 l/min)Coating: PC phosphorylcholine
dPB vs Qb
O2T vs Qb
100,0
200,0
150,0
0,0
50,0
300,0
250,0
400,0
350,0
1 2 3 4 5 6 70,50,0
Qb (lpm)
Qb (lpm)
O2T
(cc/
min
)
AA
MI S
tan
dar
d C
on
dit
ion
s
CO2T vs Qb
100,0
200,0
150,0
0,0
50,0
300,0
250,0
400,0
350,0
1 2 3 4 5 6 70,50,0
AA
MI S
tan
dar
d C
on
dit
ion
s
CO2T
(cc/
min
)
dPB
(mm
Hg)
Qb (lpm)
100,0
200,0
150,0
0,0
50,0
300,0
250,0
350,0
1 2 3 4 5 6 70,50,0
AA
MI S
tan
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d C
on
dit
ion
s
H.E. Performance Factor vs Qb(Water Flow 10 l/min)
Qb (lpm)
0,20
0,40
0,30
0,0
0,10
0,60
0,90
1,00
0,50
0,80
0,70
1 2 3 4 5 6 7 80,50,0
AA
MI S
tan
dar
d C
on
dit
ion
s
Perf
orm
ance
Fac
tor
dPB vs Qb
O2T vs Qb
100,0
200,0
150,0
0,0
50,0
300,0
450,0
250,0
400,0
350,0
1 2 3 4 5 6 7 80,50,0
Qb (lpm)
Qb (lpm)
O2T
(cc/
min
)
AA
MI S
tan
dar
d C
on
dit
ion
s
CO2T vs Qb
100,0
200,0
150,0
0,0
50,0
300,0
250,0
400,0
350,0
1 2 3 4 5 6 7 80,50,0
AA
MI S
tan
dar
d C
on
dit
ion
s
CO2T
(cc/
min
)
dPB
(mm
Hg)
Qb (lpm)
100,0
200,0
150,0
0,0
50,0
300,0
250,0
350,0
1 2 3 4 5 6 7 80,50,0
AA
MI S
tan
dar
d C
on
dit
ion
s
H.E. Performance Factor vs Qb(Water Flow 10 l/min)
Qb (lpm)
0,20
0,40
0,30
0,0
0,10
0,60
0,90
1,00
0,50
0,80
0,70
1 2 3 4 5 6 7 80,50,0
AA
MI S
tan
dar
d C
on
dit
ion
s
Perf
orm
ance
Fac
tor
SINGLE VENOUS HARDSHELL RESERVOIR
Conical dispenser to reduce suckers’
microembolic activity
TECHNICAL CHARACTERISTICS
Max volume capacity 4600 ml (approx)Max operating level 4500 ml (approx)Min. operating level 200 ml (approx)Venous filter pore Size: 80 μmCardiotomy filter pore Size: 40 μmCardiotomy reservoir ready for vacuum(equipped with over-under safety valve)
Connectors: 6 x 1/4” 1 x pOS Lock 1 x 3/8” 2 x Luer Lock
1 x pOS Lock - Luer Lock
1 x Unfiltered Luer Lock
•Clinical flexibility
•Low contact surface
•Agile pC Coating
•High volume Capacity
•Low GME activity
•Easy-to-use holder
DUAL CHAMBER VENOUS RESERVOIRLIPIDS AND LEUCOCYTES REDUCER
• Despiteimprovementsincardiopulmonarybypass(CPB) brain injury remains a significant sequela of cardiac surgery.•Cardiopulmonarybypassisassociatedwithaninflammatory reaction that involves activation of plasma proteins and cells. •Activationofleukocytes,inparticularneutrophils, directly contributes to issue and organ injury.
supernatantseparator level
CARDIOTOMYTECHNICAL CHARACTERISTICS
•Capacity(activatedbloodsection): 1800 ml (approx)•Twostepslipid-leukocytesdepletion:•Multilayercascadefiltration (for lipids and leukocytes) •Supernatantseparator (lipids only)
Cardiotomy ready for vacuum (equipped with over-under safety valve)
Connectors: 2 x 1/4” 1 x 3/8” 2 x Luer Lock 1 x pOS Lock - Luer Lock 1 x 1/4” Cell Saver outlet Line
LIP
IDS
RE
DU
CT
ION
[%
]
00
10
20
30
40
50
60
70
5 10 15 20 25 30 35 40 45 50 55 60 65
LAB
TEST
TIME (min)
00
10
20
30
40
50
60
70
5 10 15 20 25 30 35 40 45 50 55 60 65
WB
Cs
RE
DU
CT
ION
[%
]
LAB
TEST
TIME (min)
VENOUS RESERVOIRTECHNICAL CHARACTERISTICS
Capacity (non activated blood section): 3200 ml (approx)filter pore Size: 80 μmReady for vacuum (equipped with over-under safety valve)Connectors: 2 x 1/4” 1 x 3/8” 2 x Luer Lock 1 x pOS Lock - 1/4” 1 x Luer Lock unfiltered 1 x 1/4” Dedicated intracavitary port
Conical dispenser to reduce suckers’ microembolic activity
The diffuse brain damage (DBD) after cardiac operation is reported as a frequency within a range of between 20% and 80%.karl Gunnar Engstrom. The embolic potential of liquid fat in pericaldial suction blood, and its elimination. Perfusion 2003; 18:69-74
Current estimates indicate that > 50% of patients who undergo to CPB have neurological or neuropsychological deficits during the first week after surgery, 10% to 30% have long-term or permanent deficits, and 1% to 5% experience severe disability or die.William R. Brown et al. Longer duration of cardiopulmonary bypass is associated with greater numbers of cerebral microemboli. Stroke2000; 31:707-713
The scavenging of pericardial suction blood is a potential mayor source of lipid emboli during cardiopulmonary by pass. Robert F. Brooker et al. Cardiotomy Suction: a Major Source of Brain Lipid Emboli during Cardiopulmonary bypass. Ann Thorac Surg 1998; 65: 1651-5
Lipid particles in the side range of 10 μm to were characterized in shed mediastinal blood, until 300,000 particles per milliliter of blood were found.Atli Eyjolfsson, Henrik Jonsson et al. Charatcterization of Lipid Particles in Shed Mediastinal Blood. Ann Thorac Surg 2008; 85: 978-81
Embolization of lipids is not a phenomenon restricted to the brain, but affected other organs which kidneys1, spleen1 and lung2.1 Henrik Jonsson et al. Differential Distribution of Lipid Microemboli After Cardiac Surgery. Ann Thorac Surgery 2006; 81: 643-9 2 AJ de Vries et al. The rationale for fat filtration during cardiac surgery. Perfusion 2002; 17: 29-33
Activation of the systemic inflammatory response during CPB has been a mayor problem for clinicians because of the potenzial deleterious effect on organs such as the heart, brain, lung, kidneys. one strategy may be the use of leukocyte-depleting filters. Oliver Warren et al. The effect of various leukocyte fitration strategyes in cardiac surgery. Eur J Cardiothorac Surg 2007; 31: 665-676 Shalini Boodram et al. Use of Leukocyte-depleting Filters During Cardiac Surgery with Cardiopulmonary bypass: A Review. JECT 2008; 40: 27-42
*REMOWELL REFERENCES
A.L.ONE (1.35 m2)AG5000 (N° 3 pcs/pack)
(full Coated pC)
SKIPPER EU5007 (N° 2 pcs/pack)
(Oxy Module pC Coating only) REMOWELL AG5015 (N° 1 pcs/pack)
(full Coated pC)SKIPPERAG5007 (N° 2 pcs/pack)
(full Coated pC)
AMG MODULE(1.81 m2)AG5012 (N° 3 pcs/pack)
(full Coated pC)
AMG Single ChamberAG5011 (N° 2 pcs/pack)
(full Coated pC)
AMG Leuko-Lipid AG5025 (N° 1 pcs/pack)
(full Coated pC)
EU2331 (N° 1 pcs/pack) Holder (Oxy Gas Module + Reservoir)
EU2054/P (N° 1 pcs/pack) Holder for A.L.ONE/AMG gas module
ORDERING GUIDE
Distribuito daDistributed byDistribuè parVertriebDistribuido por
Prodotto daManufactured byFabriquè parHerstellerFabricado por
Eurosets s.r.l.Strada Statale 12, n°14341036 Medolla (MO) ItalyTel: +39 0535 660311Fax: +39 0535 51248E-mail: [email protected]
Rev. 12 / 2017
© Copyright 2017 by Eurosets S.r.l. - Catalogue, products, pictures may differentiate from the actual product appearance. Specifications are subject to change without prior notice.
SiNGLE VENOUS HARDSHELL RESERVOiRRE
SERV
OIR
OXYGENATOR MODULE
DUAL CHAMbER VENOUS RESERVOiRLipiDS AND LEUCOCyTES REDUCER
COMBINE
