AFAR Grant Recipients — 1981-2005

70 West 40th Street11th FloorNew York, NY 10018

The American Federation for Aging Research (AFAR) is a nonprofit organizationwhose mission is to support biomedical research on aging. We fulfill thismission by:

ä Supporting biomedical research that furthers our understanding of theaging process and its associated diseases and disorders;

ä Offering opportunities for scientists and physicians to exchange new ideasand knowledge about aging;

ä Building a cadre of early career scientists in aging research and in the practice of geriatric medicine; and

ä Promoting awareness among the general public about the importance ofaging research.

Since 1981, AFAR has awarded nearly $87 million to more than 2,100 early tomid-career investigators and students, with the goal of encouraging more ofthe nation’s scientists and physicians to enter and stay in the fields ofgerontology and geriatric medicine. These scientists are conducting cutting-edge research on aging and age-related diseases, such as Alzheimer’s, cancer,osteoporosis, diabetes and heart disease. Support for AFAR grants comes fromthe generous contributions of corporations, foundations and individuals. For more information about AFAR, please visit our organizational website,www.afar.org. For more information about aging research and staying healthyas you age, please visit our consumer websites, www.Infoaging.org andwww.HealthCompass.org.

Celebrating A Quarter Century

of Research

Letter from the Executive Director ............................1

2005 Selection Committees ....................................2

AFAR Research Grant ..............................................6

AFAR Affiliate Research Grant ................................16

AFAR/Glenn Breakthroughs in Gerontology (BIG) Award ....16

AFAR/Pfizer Innovations in Aging Research Award ............16

AFAR/Pfizer Research Grant ..............................................17

Paul Beeson Career Development Award in Aging Research ............................................................17

AFAR/Merck Junior Investigator Award in Geriatric Clinical Pharmacology........................................20

AFAR/Ellison Medical FoundationSenior Postdoctoral Fellows ............................................20

AFAR/Glenn Research Grant for Postdoctoral Fellows ........21

AFAR/Merck Research Scholarship in GeriatricPharmacology for Medical and Pharmacy Students ..........21

AFAR/Glenn Scholarship for Research in the Biology of Aging ....................................................22

AFAR/The John A. Hartford Foundation Academic FellowshipProgram in Geriatric Medicine and Geriatric Psychiatry ....27

Medical Student Summer Research Training in Aging Program ..............................................29

AFAR-Ohio Medical Student Summer Research Training inAging Program ................................................................37

AFAR/ISOA Program for Drug Discovery in Cognitive Declineand Alzheimer’s Disease ................................................38

AFAR/The Foundation for Fighting Blindness Joint Program for Career Development Awards in Support of Research onAge-Related Macular Degeneration ..................................38

AFAR/Hartford Gero-Physician-ScientistTraining Program ............................................................38

AFAR Milestones..............................................................39

Major Supporters of the 2005 Grant Programs

The AFAR Board of Directors

Anonymous Donor

The Atlantic Philanthropies

The Bedminster Fund

Cardinal Health Foundation

The Clarence and Anne Dillon Dunwalke Trust

The Cleveland Foundation

Community Health Foundation of Western & Central New York

Eisai Inc

The Ellison Medical Foundation

Lillian R. Gleitsman Foundation

The Glenn Foundation for Medical Research

The Partners of Goldman Sachs & Company

The John A. Hartford Foundation

William Randolph Hearst Foundation

Diana J. and C. A. Kalman

F. M. Kirby Foundation, Inc.

Merck Company Foundation

National Institute on Aging

The New York Community Trust

Diane Nixon

Pfizer Inc

The Richard and Hinda Rosenthal Foundation

Joseph L. K. Snyder Trust

The Starr Foundation

The Irving S. Wright Endowment

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Letter from the Executive Director25th Anniversary Grantee Directory

Stephanie Lederman

he American Federation for Aging Research (AFAR) is pleased to present its 25th anniversary grantee directory,

highlighting all of the recipients of AFAR research grants and AFAR-administered grants programs to date.

We are proud to have supported more than 2,100 early-career investigators and medical students — the best

and the brightest scientific minds in the nation — with funding of nearly $87 million. These grant recipients

have made major inroads in our understanding of how and why we age, leading to important discoveries

about how age-related diseases and disorders can be prevented or stalled.

From telomeres to stem cell research to the search for longevity genes, during the last 25 years, research

on aging has yielded substantial breakthroughs, helping to identify the rates of aging in species and the

susceptibility of disease, improving healthspan as well as lifespan.

We thank our esteemed review committee members and the many supporters who have made what we do

possible. A full listing of review committee members and supporters is contained in this directory.

A special acknowledgment and dedication of this publication goes to our dedicated board member Dorothy

Dillon Eweson, who died in June 2005. Dorothy was an early advocate for research in aging, supporting AFAR

programs that have enabled scientists to pursue and sustain careers in the field, including an endowed

lecture series that allows AFAR researchers to present their findings at annual scientific or medical specialty

association meetings. We are grateful for her longstanding commitment and generosity.

At a time of limited funding for research on aging coupled with a burgeoning aging population, AFAR’s

support is as critical as ever. As we celebrate 25 years of supporting great minds in science, we renew our

commitment to helping even more scientists gain a foothold in the area of aging research.

T

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AFAR ResearchCommitteeReviews grant proposals for theAFAR Research Grant, thePfizer/AFAR Innovations in AgingGrant, and the Ellison MedicalFoundation/AFAR SeniorPostdoctoral Research Program

RICHARD A. MILLER, M.D., Ph.D., ChairUniversity of MichiganAnn Arbor, Michigan

JUDD AIKEN, Ph.D.University of Wisconsin College of Agricultureand Life SciencesMadison, Wisconsin

ADAM ANTEBI, Ph.D.Baylor College of MedicineHouston, Texas

ANDRZEJ BARTKE, Ph.D.Southern Illinois UniversitySpringfield, Illinois

LAURA DUGAN, M.D.University of California, San DiegoSan Diego, California

JAY M. EDELBERG, M.D., Ph.D.Weill Medical College of Cornell UniversityNew York, New York

DAVID FINK, M.D.University of Michigan School of MedicineAnn Arbor, Michigan

SUZANNE GUENETTE, Ph.D.Massachusetts General Institute forNeurodegenerative DiseaseHarvard Medical SchoolBoston, Massachusetts

PATRICK R. HOF, M.D.Mount Sinai School of MedicineNew York, New York

PETER HORNSBY, Ph.D.University of Texas Health Science Center atSan AntonioSan Antonio, Texas

ROGER McCARTER, Ph.D.Pennsylvania State UniversityState College, Pennsylvania

DAVID G. MORGAN, Ph.D.University of South FloridaTampa, Florida

JAMES NELSON, Ph.D.University of Texas Health Science CenterSan Antonio, Texas

LAWRENCE RAISZ, M.D.University of Connecticut Health CenterFarmington, Connecticut

JOHN SEDIVY, Ph.D.Brown UniversityProvidence, Rhode Island

Glenn/AFARBreakthroughs inGerontology (BIG)Selection CommitteeRICHARD A. MILLER, M.D., Ph.D., ChairUniversity of MichiganAnn Arbor, Michigan

EDWARD KOO, M.D.University of California, San DiegoLa Jolla, California

GEORGE M. MARTIN, M.D.University of WashingtonSeattle, Washington

DAVID G. NICHOLLS, Ph.D.Buck Institute for Age ResearchNovato, California

JOHN SEDIVY, Ph.D.Brown UniversityProvidence, Rhode Island

MARC TATAR, Ph.D.Brown UniversityProvidence, Rhode Island

Program AdvisoryCommittee for theBeeson CareerDevelopment AwardMARY TINETTI, M.D., ChairYale University School of MedicineNew Haven, Connecticut

DAN BLAZER, M.D., Ph.D.Duke University Medical CenterDurham, North Carolina

HARVEY J. COHEN, M.D.Duke University Medical CenterDurham, North Carolina

LINDA P. FRIED, M.D., M.P.H.Johns Hopkins University Medical InstitutionsBaltimore, Maryland

WILLIAM R. HAZZARD, M.D.University of Washington School of MedicineSeattle, Washington

EDWARD KOO, M.D.University of California, San Diego La Jolla, California

LEWIS LIPSITZ, M.D.Harvard Medical SchoolBoston, Massachusetts

LINA OBEID, M.D.Medical University of South CarolinaCharleston, South Carolina

ALAN R. SHULDINER, M.D.University of Maryland School of MedicineBaltimore, Maryland

Merck/AFAR JuniorInvestigators inGeriatric ClinicalPharmacologyMARK BEERS, M.D., ChairMerck & Company, Inc.West Point, Pennsylvania

MEGHAN GERETY, M.D.University of Texas Health Science CenterSan Antonio, Texas

BRUCE POLLOCK, M.D., Ph.D.University of PittsburghPittsburgh, Pennsylvania

The Medical StudentSummer Training inAging ProgramPATRICIA BARRY, M.D., M.P.H., ChairMerck Institute of Aging and HealthWashington, D.C.

RONALD D. ADELMAN, M.D.Weill Medical College of Cornell UniversityNew York, New York

THOMAS A. CAVALIERI, D.O.UMDNJ-School of Osteopathic MedicineStratford, New Jersey

JAMES L. RUDOLPH, M.D.Harvard Medical SchoolBoston, Massachusetts

CRYSTAL SIMPSON, M.D., M.H.S.Johns Hopkins UniversityBaltimore, Maryland

ANITA WOODS, Ph.D.Baylor College of MedicineHouston, Texas

NATIONAL SCIENTIFICADVISORY COUNCIL(NSAC)Reviews grant proposals for theAFAR Research Grant, thePfizer/AFAR Innovations in AgingGrant, and the Ellison MedicalFoundation/AFAR SeniorPostdoctoral Research Program

CARMELA R. ABRAHAM, Ph.D.Boston University School of MedicineBoston, Massachusetts

ITAMAR ABRASS, M.D.University of WashingtonSeattle, Washington

AYOTUNDE ADEAGBO, Ph.D.University of LouisvilleLouisville, Kentucky

NEIL ALEXANDER, M.D.University of MichiganAnn Arbor, Michigan

KATRIN ANDREASSON, M.D.Johns Hopkins University School of MedicineBaltimore, Maryland

ROBERT ARKING, Ph.D.Wayne State UniversityDetroit, Michigan

NANCY L. BAENZIGER, Ph.D.Washington UniversitySt. Louis, Missouri

BEN A. BAHR, Ph.D.University of ConnecticutStorrs, Connecticut

NIR BARZILAI, M.D.Albert Einstein College of MedicineBronx, New York

JOHN BAUM, M.D.University of RochesterRochester, New York

GAL BITAN, Ph.D.David Geffen School of Medicine at UCLALos Angeles, California

ROBERT BLANK, M.D., Ph.D.University of Wisconsin Medical SchoolMadison, Wisconsin

VILHELM A. BOHR, M.D., Ph.D.National Institute on AgingNational Institutes of HealthBaltimore, Maryland

ROBERT A. BONOMO, M.D.Louise Stokes Cleveland VAMCCleveland, Ohio

ADELE BOSKEY, Ph.D.Hospital for Special SurgeryNew York, New York

2005 AFAR Selection Committees

AFAR’s committees are comprised of experts in aging research and relatedareas of research who volunteer their time and expertise to the AFARreview processes. Their dedication, enthusiasm and commitment is crucialto the success of AFAR’s grant programs.

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JOSEPH BRESSLER, Ph.D.Johns Hopkins University School of PublicHealthBaltimore, Maryland

JACOB A. BRODY, M.D.University of Illinois at ChicagoChicago, Illinois

SUSAN BROOKS, Ph.D.University of MichiganAnn Arbor, Michigan

HOLLY M. BROWN-BORG, Ph.D.University of North Dakota School of MedicineGrand Forks, North Dakota

JOHN N. BUCHHOLZ, Ph.D.Loma Linda University School of MedicineLoma Linda, California

JOCHEN BUCK, M.D., Ph.D.Weill Medical College of Cornell UniversityNew York, New York

JAMES BURKE, M.D., Ph.D.Duke University Medical CenterDurham, North Carolina

KATHERINE G. BUTLER, Ph.D.San Jose State UniversityMonterey, California

JAMES CAREY, Ph.D.University of California, DavisDavis, California

CATHY CARLSON, D.V.M., Ph.D.University of MinnesotaSt. Paul, Minnesota

MONICA J. CARSON, Ph.D.University of California, RiversideRiverside, California

MARY LOU CASPERS, Ph.D.University of Detroit MercyDetroit, Michigan

PRISCILLA CLARKSON, Ph.D.University of MassachusettsAmherst, Massachusetts

DENNIS O. CLEGG, Ph.D.University of California, Santa BarbaraSanta Barbara, California

HARVEY JAY COHEN, M.D.Duke University Medical CenterDurham, North Carolina

KEVIN CONLEY, Ph.D.University of Washington Medical CenterSeattle, Washington

VINCENT L. CRYNS, M.D.Northwestern University School of MedicineChicago, Illinois

ANA MARIA CUERVO, M.D., Ph.D.Albert Einstein College of MedicineBronx, New York

CHRISTINE CURCIO, Ph.D.University of Alabama School of MedicineBirmingham, Alabama

MARK D’ESPOSITO, M.D.University of California, BerkeleyBerkeley, California

WILLIAM DALE, M.D., Ph.D.University of ChicagoChicago, Illinois

KELVIN DAVIES, Ph.D.University of Southern CaliforniaLos Angeles, California

LUISA DiPIETRO, D.D.S., Ph.D.Loyola UniversityMaywood, Illinois

LINDA A. DOKAS, Ph.D.Medical College of OhioToledo, Ohio

EVAN DREYER, M.D., Ph.D.Glaucoma Cataract ConsultantsPittsburgh, Pennsylvania

MONICA DRISCOLL, Ph.D.Rutgers UniversityPiscataway, New Jersey

GUSTAVO DUQUE, M.D.McGill University Health CentreMontreal, Canada

CATHERINE DUBEAU, M.D.University of ChicagoChicago, Illinois

KAREN DUFF, Ph.D.Nathan Kline Institute/New York UniversityOrangeburg, New York

GUSTAVO DUQUE, M.D., Ph.D.McGill University Health CentreMontreal, Canada

STEVE ESTUS, Ph.D.University of Kentucky Medical CenterLexington, Kentucky

JIM R. FADEL, Ph.D.University of South Carolina School ofMedicineColumbia, South Carolina

JEFF C. FALCONE, Ph.D.University of Louisville Health Science CenterLouisville, Kentucky

MEL B. FEANY, M.D., Ph.D.Brigham and Women’s Hospital/HarvardUniversityBoston, Massachusetts

DEBORAH A. FERRINGTON, Ph.D.University of MinnesotaMinneapolis, Minnesota

ROGER FIELDING, Ph.D.Tufts UniversityBoston, Massachusetts

TRACY L. FITZGERALD, Ph.D.University of Maryland, College ParkCollege Park, Maryland

JEROME FLEG, M.D.National Heart, Lung, and Blood InstituteNational Institutes of HealthBethesda, Maryland

ROBERT FLOYD, Ph.D.University of Oklahoma Health Science CenterOklahoma City, Oklahoma

MARY KAY FRANCIS, Ph.D.Villanova UniversityVillanova, Pennsylvania

ROBERT R. FREEDMAN, Ph.D.Wayne State University School of MedicineDetroit, Michigan

SALLY FRENKEL, Ph.D.New York University Hospital for Joint DiseasesNew York, New York

MATTHEW P. FROSCH, M.D. Ph.D.Massachusetts General HospitalHarvard Medical SchoolCharlestown, Massachusetts

LORISE C. GAHRING, Ph.D.University of Utah School of MedicineSalt Lake City, Utah

DOUGLAS R. GALASKO, M.D.VA Medical CenterUniversity of California, San DiegoSan Diego, California

JAMES W. GAUBATZ, Ph.D.University of South AlabamaMobile, Alabama

DEBRA GEARHART, Ph.D.University of Georgia College of PharmacyAugusta, Georgia

GODFREY S. GETZ, M.D., Ph.D.The University of ChicagoChicago, Illinois

THOMAS M. GILL, M.D.Yale University School of MedicineNew Haven, Connecticut

TODD GOLDE, M.D., Ph.D.Mayo Medical SchoolJacksonville, Florida

JAMES S. GOODWIN, M.D.The University of Texas Medical BranchGalveston, Texas

ANDREA C. GORE, Ph.D.The University of Texas at AustinAustin, Texas

LUC E. GOSSELIN, Ph.D.University at Buffalo - SUNYBuffalo, New York

GUNNAR K. GOURAS, M.D.Weill Medical College of Cornell UniversityNew York, New York

LOTTA GRANHOLM-BENTLEY, Ph.D., D.D.S.Medical University of South CarolinaCharleston, South Carolina

SUZANNE GUENETTE, Ph.D.Massachusetts General Hospital/HarvardMedical SchoolCharlestown, Massachusetts

THEODORE J. HAHN, M.D.VA West Los Angeles Healthcare CenterUniversity of California, Los AngelesLos Angeles, California

ROGER HAJJAR, M.D.Massachusetts General Hospital/HarvardMedical SchoolCharlestown, Massachusetts

COURTNEY D. HALL, Ph.D., P.T.Emory University/Atlanta VAMCAtlanta, Georgia

JEFFREY M. HAUSDORFF, Ph.D.Tel-Aviv Sourasky Medical CenterTel Aviv, Israel

LAURA HAYNES, Ph.D.Trudeau InstituteSaranac Lake, New York

STEPHEN L. HELFAND, M.D.University of Connecticut Health CenterFarmington, Connecticut

BOB HELFERT, Ph.D.Southern Illinois University School of MedicineSpringfield, Illinois

JANET HENDERSON, Ph.D.Centre for Bone & Periodontal ResearchMontreal, Quebec

BRIAN HERMAN, Ph.D.University of Texas Health Science CenterSan Antonio, Texas

AHMAD HEYDARI, Ph.D.Wayne State UniversityDetroit, Michigan

FUKI HISAMA, M.D.Yale University School of MedicineNew Haven, Connecticut

PATRICK R. HOF, M.D.Mount Sinai School of MedicineNew York, New York

SHAWN HOLT, Ph.D.Medical College of Virginia at VCURichmond, Virginia

ERIC W. HOWARD, Ph.D.University of Oklahoma Health Science CenterOklahoma City, Oklahoma

KAREN HUBBARD, Ph.D.The City College of New YorkNew York, New York

MICHAEL L. HUTTON, Ph.D.Mayo Medical SchoolJacksonville, Florida

DONALD K. INGRAM, Ph.D.National Institute on AgingNational Institutes of HealthBaltimore, Maryland

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BRAD JOHNSON, M.D., Ph.D.University of PennsylvaniaPhiladelphia, Pennsylvania

THOMAS E. JOHNSON, Ph.D.University of ColoradoBoulder, Colorado

THOMAS JONES, M.D., M.P.H.Merck & Co., Inc.West Point, Pennsylvania

EVAN KELLER, D.V.M., Ph.D.University of MichiganAnn Arbor, Michigan

JEFF KELLER, Ph.D.University of Kentucky, LexingtonLexington, Kentucky

ANNE KENNY, M.D.University of Connecticut Health CenterFarmington, Connecticut

STUART KIM, Ph.D.Stanford UniversityStanford, California

WENDY KOHRT, Ph.D.University of Colorado Health Science CenterDenver, Colorado

CATHERINE M. KOTZ, Ph.D.Veterans Affairs Medical Center/University ofMinnesotaMinneapolis, Minnesota

DORA KOVACS, Ph.D.Massachusetts General Hospital/HarvardMedical SchoolBoston, Massachusetts

BRUCE S. KRISTAL, Ph.D.Burke Medical Research InstituteWhite Plains, New York

HARLAN KRUMHOLZ, M.D.Yale University School of MedicineNew Haven, Connecticut

GEORGE A. KUCHEL, M.D.University of Connecticut Health CenterFarmington, Connecticut

DONALD M. KUHN, Ph.D.Wayne State UniversityDetroit, Michigan

WALTER A. KUKULL, Ph.D.University of WashingtonSeattle, Washington

ALBERT LA SPADA, M.D., Ph.D., FACMGUniversity of WashingtonSeattle, Washington

JAMES J. LAH, M.D., Ph.D.Emory UniversityAtlanta, Georgia

PAMELA LARSEN, Ph.D.University of Texas Health Science CenterSan Antonio, Texas

PHONG T. LE, Ph.D.Loyola University Medical CenterMaywood, Illinois

WILLIAM LEE, Ph.D.The David Axelrod InstituteAlbany, New York

ALLAN I. LEVEY, M.D., Ph.D.Emory UniversityAtlanta, Georgia

RICHARD Z. LIN, M.D.State University of New York, Stony BrookStony Brook, New York

ROBERT D. LINDEMAN, M.D.The University of New MexicoAlbuquerque, New Mexico

GORDON LITHGOW, Ph.D.The Buck Institute for Age ResearchNovato, California

GUOSONG LIU, M.D., Ph.D.MIT/Picower Center for Learning & MemoryCambridge, Massachusetts

RICHARD F. LOESER, Jr., M.D.Wake Forest University School of MedicineWinston-Salem, North Carolina

VALTER D. LONGO, Ph.D.University of Southern CaliforniaLos Angeles, California

KENNETH W. LYLES, M.D.Duke University Medical CenterDurham, North Carolina

FERNANDO MACIAN, M.D., Ph.D.Albert Einstein College of MedicineBronx, New York

ROBERT MARCINIAK, M.D., Ph.D.University of Texas Health Science CenterSan Antonio, Texas

GEORGE M. MARTIN, M.D.University of Washington School of MedicineSeattle, Washington

MARK MATTSON, Ph.D.National Institutes for HealthNational Institute of AgingBaltimore, Maryland

SKYE McDOUGALL, Ph.D.West Los Angeles VAMC GRECCLos Angeles, California

RAVI MISRA, Ph.D.Medical College of WisconsinMilwaukee, Wisconsin

CHARLES V. MOBBS, M.D.Mount Sinai School of MedicineNew York, New York

SUMATHY MOHAN, Ph.D.University of Texas Health Science Center atSan AntonioSan Antonio, Texas

ROBERT D. MOIR, Ph.D.Massachusetts General Hospital/HarvardMedical SchoolCharlestown, Massachusetts

SHIN MURAKAMI, Ph.D.University of Louisville Medical SchoolLouisville, Kentucky

MOHAN NATARAJAN, Ph.D.University of Texas Health Science CenterSan Antonio, Texas

BIJAYA NAYAK, Ph.D.University of Texas Health Science CenterSan Antonio, Texas

DAVID G. NICHOLLS, Ph.D.Buck Institute for Age ResearchNovato, California

LAURA NIKLASON, M.D., Ph.D.Duke UniversityDurham, North Carolina

MARIANA NIKOLOVA-KARAKASHIAN, Ph.D.University of KentuckyLexington, Kentucky

HERNANDO OMBAO, Ph.D.University of IllinoisChampaign, Illinois

JUNKO OSHIMA, M.D., Ph.D.University of WashingtonSeattle, Washington

ADAM PACK, Ph.D.Utica College of Syracuse UniversityUtica, New York

MARCO PAHOR, M.D.University of Florida College of MedicineGainesville, Florida

DAVID PAIK, M.D.Columbia UniversityNew York, New York

OLIVIA M. PEREIRA-SMITH, Ph.D.University of Texas Health Science CenterSan Antonio, Texas

GEORGE PERRY, Ph.D.Case Western Reserve UniversityCleveland, Ohio

ROBERT B. PETERSEN, Ph.D.Case Western Reserve UniversityCleveland, Ohio

ERIC PETERSON, M.D., M.P.H.Duke Clinical Research InstituteDurham, North Carolina

PETER POMPEI, M.D.Stanford University Medical CenterStanford, California

DOMENICO PRATICO, M.D.University of PennsylvaniaPhiladelphia, Pennsylvania

DANIEL PROMISLOW, Ph.D.University of GeorgiaAthens, Georgia

LeBRIS QUINN, Ph.D.VA Puget Sound Health Care SystemTacoma, Washington

JACOB RABER, Ph.D.Oregon Health & Science UniversityPortland, Oregon

JOE RAMSDELL, M.D.University of California, San DiegoSan Diego, California

THOMAS RANDO, M.D., Ph.D.Stanford University/VAPACSPalo Alto, California

MAHENDRA RAO, M.D., Ph.D.National Institute on AgingNational Institutes of HealthBaltimore, Maryland

JANE RECKELHOFF, Ph.D.University of Mississippi Medical CenterJackson, Mississippi

P. HEMACHANDRA REDDY, Ph.D.Oregon Health and Sciences UniversityBeaverton, Oregon

JOANNE ROBBINS, Ph.D.William S. Middleton VA HospitalUniversity of Wisconsin, MadisonMadison, Wisconsin

JACK ROGERS, Ph.D.Harvard Medical SchoolCharlestown, Massachusetts

SCOTT W. ROGERS, Ph.D.University of UtahSalt Lake City, Utah

MICHAEL ROSE, Ph.D.University of California, IrvineIrvine, California

JOYCE A. RUBENSTEIN, Ph.D.Long Island University - CW Post CampusManhasset Hills, New York

BART RYPMA, Ph.D.Rutgers UniversityNewark, New Jersey

KATHRYN L. SANDBERG, Ph.D.Georgetown University Medical CenterWashington, DC

JULIE SANDELL, Ph.D.Boston University School of MedicineBoston, Massachusetts

NANETTE SANTORO, M.D.Albert Einstein College of MedicineBronx, New York

MARTIN F. SARTER, Ph.D.University of MichiganAnn Arbor, Michigan

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RALPH H. SAUNDERS, D.D.S.The University of RochesterRochester, New York

DOUGLAS L. SCHMUCKER, Ph.D.University of California at San FranciscoSan Francisco, California

MICHAEL SEIDMAN, Ph.D.National Institute on AgingNational Institutes of HealthBaltimore, Maryland

YONG SHEN, M.D., Ph.D.Sun Health Research InstituteSun City, Arizona

BARBARA SHUKITT-HALE, Ph.D.Tufts UniversityBoston, Massachusetts

ALAN R. SHULDINER, M.D.University of Maryland, BaltimoreBaltimore, Maryland

FELIPE SIERRA, Ph.D.National Institute of AgingNational Institutes of HealthBaltimore, Maryland

RAM SIHAG, Ph.D.Food and Drug AdministrationBethesda, Maryland

DAVID A. SINCLAIR, Ph.D.Harvard Medical SchoolBoston, Massachusetts

DAN F. SPANDAU, Ph.D.Indiana University School of MedicineIndianapolis, Indiana

JANET R. SPARROW, Ph.D.Columbia UniversityNew York, New York

JOSEPH W. STARNES, Ph.D.University of Texas, AustinAustin, Texas

JOHN R. STRATTON, M.D.University of WashingtonSeattle, Washington

WARREN J. STRITTMATTER, M.D.Duke University Medical CenterDurham, North Carolina

JANET S. SUNNESS, M.D.Johns Hopkins Wilmer InstituteBaltimore, Maryland

MARK SUPIANO, M.D.University of MichiganAnn Arbor, Michigan

BETSY M. SUTHERLAND, Ph.D.Brookhaven National LaboratoryUpton, New York

PHILLIP D. SWANSON, M.D., Ph.D.University of WashingtonSeattle, Washington

KAREN L. SWISSHELM, Ph.D.University of WashingtonSeattle, Washington

GEORGE E. TAFFET, M.D.Baylor College of MedicineHouston, Texas

MARC TATAR, Ph.D.Brown UniversityProvidence, Rhode Island

DENNIS D. TAUB, Ph.D.National Institute on AgingNational Institutes of HealthBaltimore, Maryland

J. ANDREW TAYLOR, Ph.D.Spaulding Rehabilitation HospitalHarvard Medical SchoolBoston, Massachusetts

DARRYL G. THELEN, Ph.D.University of Wisconsin, MadisonMadison, Wisconsin

D. PAUL THOMAS, Ph.D.University of WyomingLaramie, Wyoming

LA DORA THOMPSON, Ph.D.University of MinnesotaMinneapolis, Minnesota

JONATHAN L. TILLY, Ph.D.Massachusetts General HospitalHarvard UniversityBoston, Massachusetts

NIKOLAI TIMCHENKO, Ph.D.Baylor College of MedicineHouston, Texas

JOHN G. TOWER, Ph.D.University of Southern CaliforniaLos Angeles, California

BRUCE R. TROEN, M.D.University of Miami School of MedicineMiami, Florida

DEAN A. TROYER, M.D.University of Texas Health Science CenterSan Antonio, Texas

DENNIS A. TURNER, M.D.Duke University Medical CenterDurham, North Carolina

R. SCOTT TURNER, M.D. Ph.D.University of MichiganAnn Arbor, Michigan

HOLLY VAN REMMEN, Ph.D.University of Texas Health Science CenterSan Antonio, Texas

GARY VAN ZANT, Ph.D.University of KentuckyLexington, Kentucky

INEZ VINCENT, Ph.D.University of WashingtonSeattle, Washington

B.J. WAGNER, Ph.D.UMDNJ-New Jersey Medical SchoolNewark, New Jersey

WALTER F. WARD, Ph.D.University of Texas Health Science CenterSan Antonio, Texas

GORDON WARREN, Ph.D.Georgia State UniversityAtlanta, Georgia

BABETTE WEKSLER, M.D.Weill Medical School of Cornell UniversityNew York, New York

FLETCHER WHITE, Ph.D.Loyola University Medical CenterMaywood, Illinois

DAVID L. WILSON, Ph.D.University of MiamiCoral Gables, Florida

GLENN L. WILSON, Ph.D.University of South AlabamaMobile, Alabama

DANIEL E. WOLLMAN, M.D., Ph.D.Center for Comprehensive CareShelton, Connecticut

PHILIP C. WONG, Ph.D.The Johns Hopkins University School ofMedicineBaltimore, Maryland

DIANA WOODRUFF-PAK, Ph.D.Temple University/Albert Einstein MedicalCenterPhiladelphia, Pennsylvania

WEIMING XIA, Ph.D.Harvard Institute of MedicineBoston, Massachusetts

DEAN T. YAMAGUCHI, M.D., Ph.D.VA Greater Los Angeles Healthcare SystemLos Angeles, California

RIQIANG YAN, Ph.D.The Cleveland Clinic FoundationCleveland, Ohio

RAYMOND YUNG, M.D.University of MichiganAnn Arbor, Michigan

MARCO ZARBIN, M.D., Ph.D.New Jersey Medical SchoolNewark, New Jersey

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2005 GranteesRajendra S. Apte, M.D., Ph.D.Washington UniversityAging and the Immune System: Implicationsfor Ocular Angiogenesis

Stanley Thomas Carmichael, M.D., Ph.D.David Geffen School of Medicine at theUniversity of California, Los AngelesMolecular Profile of Neuronal Regenerationin the Aged Brain after Stroke

Christopher J. Chang, Ph.D.University of California, BerkeleyMolecular Imaging Probes for Age-relatedOxidative Stress and Damage

Jim R. Fadel, Ph.D.University of South Carolina School ofMedicineOrexin Regulation of the Basal ForebrainCholinergic System in Aged Rats

Insoo Kang, M.D.Yale University School of MedicineThe Effect of Aging on IL-7-mediated CD8+T-cell Survival

Radhakrishnan Nagarajan, Ph.D.University of Arkansas for Medical SciencesModeling Changes in Myogenic ProgenitorPotential with Age

Olav Rueppell, Ph.D.University of North Carolina, GreensboroMitosis and Apoptosis in Relation to Lifespanin the Honey Bee (Apis Mellifera L.)

Hongbing Wang, Ph.D.Michigan State Universityß-Amyloid Precurson Protein-mediatedSignaling Through FE65

Tian Wang, Ph.D.Yale University School of MedicineThe Effect of Aging on Gamma Delta T-cellResponse to Nile Virus Infection in MouseModel

2004 GranteesGal Bitan, Ph.D.Brigham and Women’s Hospital/HarvardMedical SchoolDevelopment of Amyloid ß-ProteinOligomerization Inhibitors

Bo-Chin Chiu, Ph.D.University of MichiganEffect of Aging on Early Events ofPulmonary Innate Immune Response toMycobacterial Antigen Challenge in MouseModels

Wolfgang B. Liedtke, M.D., Ph.D.Duke University Medical CenterMolecular Pathogenesis of OsmoticDysregulation by the Nervous System inAging Mammals

Jianyuan Luo, Ph.D.University of Massachusetts Medical SchoolNegative Regulation of p53 Pathway byMammalian Sir2 Antagonize p53 DependentCell Senescence Induced by Oxidative Stress

Barbara McCreadie, Ph.D.University of MichiganAge-related Response to Trabecular BoneMicrodamage

M. Paul Murphy, Ph.D.Mayo Clinic College of Medicine, JacksonvilleRegulation of ß-Secretase by CNBP

Radhika H. Muzumdar, M.D.Albert Einstein College of MedicineRole of Declining IGF-1 in the MetabolicSyndrome of Aging

Peter Penzes, Ph.D.Northwestern UniversityRegulation of Structural Plasticity ofExcitatory Synapses

Pere Puigserver, Ph.D.Johns Hopkins University School of MedicineMolecular Mechanisms for TranscriptionalRegulation of Glucose Homeostatis Linkedto Aging

Patrick M. Sullivan, Ph.D.Duke University Medical CenterEffective Aging on Brain ApoE-dependent,Lipid Metabolism

Kaoru Tominaga, Ph.D.University of Texas Health Science Center atSan AntonioAnalysis of MORF4 Functions In Vitro and InVivo Model Systems

Zoltan Ungvari, M.D., Ph.D.New York Medical CollegeCardiovascular Protective Effects of Anti-TNFa/TACE Treatment in Aging

David N. Zacks, M.D., Ph.D.University of Michigan Kellogg Eye CenterApoptosis in Photoreceptor Cell Death

2003 GranteesDouglas E. Faunce, Ph.D.Loyola University Medical CenterA Role for Natural Killer T-cells in Age-relat-ed Immune Dysfunction

Gonzalo G. Garcia, Ph.D.University of MichiganEffects of Surface Glycosylation in the Age-related Decline of T-cell function

Ming Guo, M.D., Ph.D.David Geffen School of Medicine at theUniversity of California, Los AngelesIdentifying Regulators of Gamma SecretaseImplicated in Alzheimer’s Disease

Daniel G. Herrera, M.D., Ph.D.Weill Medical College of Cornell UniversityEffects of Alcoholism on Neurogenesis inthe Aged Brain

Elizabeth Jonas, M.D.Yale University School of MedicineEnhancement of Synaptic Function by aBCL-2 Family Protein

David E. Kang, Ph.D.University of California, San DiegoRole of Presenilin in Phosphorylation of Tau

Brian K. Kennedy, Ph.D.University of WashingtonGenome-wide Identification of Yeast AgingGenes

Christine Maric, Ph.D.Georgetown University Medical CenterEstrogen Modulation of the Renin-Angiotensin System in the Pathogenesis ofAge-related Progressive Renal Disease

Kelly L. Tremblay, Ph.D.University of WashingtonAging and the Neural Representation ofSpeech-Sounds: Effects of Hearing AidAmplification and Auditory Training

Edwin J. Weeber, Ph.D.Vanderbilt University Medical CenterThe Role of ApoE Receptors inHippocampal-dependent Synaptic Function

Gang Yu, Ph.D.University of Texas Southwestern MedicalCenterDissecting Molecular Interactions of PEN-2in the ß-Secretase Complex

2002 GranteesMary L. Bouxsein, Ph.D.Beth Israel Deaconess Medical CenterThe Role of ß-Arrestin2 in Regulating theEffects of PTH in Bone

Francesco S. Celi, M.D.University of Maryland, BaltimoreType-2 Deiodinase Mutations and InsulinResistance in the Old Order of Amish

Linda L. Chao, Ph.D.University of California, SanFrancisco/Veterans Affairs Medical CenterfMRI of Attention and Inhibitory Control inNormal Aging

Paola Fabrizio, Ph.D.University of Southern CaliforniaThe Role of Evolutionary Conserved Proteinsin Yeast Longevity

Thomas J. Gould, Ph.D.Temple UniversityInvestigation of Age-related Changes inMolecular Substrates of Learning inTransgenic Mice

Mark Hoffman, Ph.D.Oregon State UniversityReflex Modulation during Manipulation ofthe Sensory Systems

Xudong Huang, Ph.D.Massachusetts General HospitalHomocysteine, Oxidative Stress andMitochondria-dependent Neuronal Apoptosisin Alzheimer’s Disease

Mark Laubach, Ph.D.The John B. Pierce LaboratoryNeurophysiological Correlates of Aging onReaction Time Performance

Yi-Ju Li, Ph.D.Duke University Medical CenterIdentification of Novel Age-at-Onset Geneson Chromosome 10 in Alzheimer’s Disease

Philippe Marambaud, Ph.D.Mount Sinai School of MedicineRole of the Presenilin-1/ß-secretaseCleavage of E-Cadherin in AdherensJunction Functions

David J. Moser, Ph.D.University of Iowa Carver College of MedicineEffects of Endothelial DysfunctionCerebrovascular Disease, Cognition andDepression

Susan R. Opalenik, Ph.D.Vanderbilt UniversityStem Cells in Age-impaired Wound Healing

Giovanni Paternostro, M.D., Ph.D.Burnham InstituteGenetic Analysis of Cardiac Aging inDrosophila

Qitao Ran, Ph.D.University of Texas Health Science Center atSan AntonioWill Reduced Level of PHGPx (GPx4) inBrain Facilitate the Formation of AmyloidPlaques?

P. Hemachandra Reddy, Ph.D.Oregon Health and Science UniversityMolecular Analysis of Synaptopodin Gene: APossible Genetic Link with Late-onsetAlzheimer’s Disease

Molly Shores, M.D.Veterans Affairs Puget Sound Health CareSystemThe Effect of Testosterone Treatment onDepressive Symptoms and Quality of Life inOlder Men with Age-associatedHypogonadism and SubsyndromalDepression

Adrian M. Timmers, Ph.D.University of FloridaAccumulation of Age-pigment in RetinalPigment Epithelium and Age-related MacularDegeneration

AFAR Research GrantOne- to two-year awards to junior faculty (M.D.’s and Ph.D.’s) to conductresearch that will serve as the basis for longer term research efforts.Sponsored by Individuals, Corporations and Foundations.

* Institution affiliation at time of award listed

7

Heidi A. Tissenbaum, Ph.D.University of Massachusetts Medical SchoolGenetic and Molecular Analysis ofMechanisms Controlling Life Span in C. elegans

2001 GranteesChristy S. Carter, Ph.D.Wake Forest School of MedicinePhysical Ability in Aged and Dwarf(dw/dw)Rats: Isolating Growth Hormone Effects

John P. Case, M.D.Rush-Presbyterian-St. Luke’s Medical CenterRelationship between Dynamic JointLoading, Bone Mineral Density, andRadiographic Predictors of EarlyOsteoarthritis in the Elderly

Atanu Duttaroy, Ph.D.Howard UniversityGenomic Regions Involved in ManganeseSuperoxide Dismutase Regulation inDrosophila

Peter Erhardt, M.D., Ph.D.Boston Biomedical Research InstituteRegulation of Cardiomyocyte Survival byMDM2

Karen Furie, M.D., M.P.H.Spaulding Rehabilitation HospitalApolipoprotein E Genotype and FunctionalRecovery Following Rehabilitation afterIschemic Stroke

ZhongMao Guo, M.D., Ph.D.Meharry Medical CollegeDoes Calorie Restriction RetardAtherosclerosis in Transgenic Mice?

David F. Jarrard, M.D.University of WisconsinGenomic Imprinting Alterations inSenescence

Dawn A. Lowe, Ph.D.University of MinnesotaMolecular Mechanism of Age-relatedDeclines in Muscle Contractility

Gianni F. Maddalozzo, Ph.D.Oregon State UniversityThe Separate and Combined Effect ofEstrogen Replacement Therapy (ERT) andResistance Training on the Musculoskeletaland Nervous System in EarlyPostmenopausal Women

Robert Moir, Ph.D.Massachusetts General HospitalLRP-mediated Uptake of Redox Modified ADAssociated Proteins

Laura E. Niklason, M.D., Ph.D.Duke University Medical CenterTelomerase in Engineered Vascular Tissues

Claudia A. Orengo, M.D., Ph.D.Baylor College of MedicineTestosterone Augmentation in DepressedMen with Partial Response to Anti-depres-sant Therapy

Maricarmen Planas-Silva, Ph.D.Penn State University College of MedicineEstrogen Receptor Expression and Functionin the Aging Mammary Gland

Troy T. Rohn, Ph.D.Boise State UniversityThe Role of Caspase-8 in MediatingNeuronal Cell Death Associated withAlzheimer’s Disease: A Potential TherapeuticTarget

Patricia W. Slattum, Pharm.D., Ph.D.Virginia Commonwealth UniversityAge-related Differences in the Sensitivityand Development of Acute Tolerance toEthanol in Humans

Sundar Srinivasan, Ph.D.University of WashingtonRest-inserted Loading: Examination of aNovel Osteogenic Stimulus for the AgedSkeleton

Mei Sun, Ph.D.West Roxbury Veterans AffairsHospital/Harvard Medical SchoolDeveloping Gene Therapy for Parkinson’sDisease Using Helper Virus-free HSV-1Vectors

Ruben G. Vidal, Ph.D.Indiana University School of MedicineThe BRI Gene Family and Familial Britishand Danish Dementia

Suresh Viswanathan, M.S., Ph.D.Indiana University School of OptometryIdentifying the Retinal Loci of Age-relatedChanges in Rod-mediated Visual Function

Beverly M. Yashar, M.S., Ph.D.University of MichiganMolecular Genetics Studies of Age-relatedMacular Degeneration

Clare E. Yellowley, Ph.D.Penn State University College of MedicineInteractions of Age and Ovariectomy onBone Cell Mechanosensitivity: Recovery byPTH Administration

2000 GranteesJames A. Carson, Ph.D.University of South CarolinaSerum Response Factor’s Role in AgedSkeletal Muscle’s Blunted RemodelingResponse to Chronic Stretch

Qin Mary Chen, Ph.D.University of ArizonaMolecular Mechanisms of Oxidative StressResponse in Cardiomyocytes

Charleen T. Chu, M.D., Ph.D.University of PittsburghSuperoxide and Nitric Oxide in aParkinsonian Mouse Model

Ana Maria Cuervo, M.D., Ph.D.Albert Einstein College of MedicineChanges in the Lysosomal Receptor forChaperone-mediated Autophagy with Age

Esther Dupont-Versteegden, Ph.D.Donald W. Reynolds Center on Aging at theUniversity of Arkansas Medical SchoolThe Role of Calcineurin in Age-associatedMuscle Atrophy

David A. Goukassian, M.D., Ph.D.Boston University School of MedicineThe Effect of Aging on DNA Repair andMutation Rate: Modulation by DNAOligonucletide Therapy

Claudia Gravekamp, Ph.D.Cancer Therapy and Research CenterA Syngeneic Mouse Tumor Model toDevelop Cancer Vaccines for the Elderly

Qing Guo, Ph.D.Northeastern Ohio Universities School ofMedicineInhibiting Aberrant Processing ofAlzheimer’s ß-Amyloid Precursor Protein byBlocking Par-4 Activity: Novel TherapeuticImplications in the Treatment of Alzheimer’sDisease

Paul S. Hees, Ph.D.Johns Hopkins Bayview Medical CenterReversal of Age-related Myocardial Stiffnessin Rats

Shurong Huang, Ph.D.Palo Alto Institute of Molecular MedicineRegulation of Replicative Senescence by theWRN Gene

Jennifer I. Luebke, Ph.D.Boston University School of MedicineFunctional Consequences of CholinergicDegeneration in Aged Rhesus Monkeys

Allen Mandir, M.D., Ph.D.Johns Hopkins UniversityAging & Parkinson’s Disease: MPTP Modelsof Neurotoxicity

Michael J. McEachern, Ph.D.University of GeorgiaGenomic Screen for Telomere Mutants

Timothy P. O’Connor, Ph.D.City College of the City University of New YorkAging of Gut Function and Metabolism in aLong-lived Rodent, the Naked Mole-Rat

Riccardo Perfetti, M.D., Ph.D.Cedars-Sinai Medical CenterAge-dependent Decline of Pancreatic IsletCell Function is Reversed by HormonalTreatment

Suzana Petanceska, Ph.D.Nathan Kline InstituteModeling the Role of Microglia in aßDeposition: Effect of Estrogen

David A. Sinclair, Ph.D.Harvard Medical SchoolA Molecular Role for Werner and Sgs1Helicases in Telomere Maintenance andPremature Aging

Nina J. Solenski, M.D.University of Virginia Health SystemThe Role of Mitochondria in Hypoxia-induced Cell Death

Aziz M. Ulug, Ph.D.Weill Medical College of Cornell UniversityThe Diagnosis and Management of NormalPressure Hydrocephalus in the Elderly UsingMRDTI

Demetri Vassilatis, Ph.D.Baylor College of MedicineCaenorhabditis elegans as a Model forParkinson’s Disease

Robert West, Ph.D.University of Notre DameThe Neural Foundation of Age-relatedDeclines in Prospective Memory

Asma Zaidi, Ph.D.University of KansasAge-related Alterations in the PlasmaMembrane Ca2+-ATPase: Role of OxidativeStress and Ceramide Signaling

1999 GranteesAyotunde S.O. Adeagbo, Ph.D.University of LouisvilleThe Aging Factor in Potassium Cycling andBlood Vessel Relaxation

Nancy J.O. Birkmeyer, Ph.D.Dartmouth UniversityA National Study of Aortic ValveReplacement in the Elderly

William J. Bowers, Ph.D.University of Rochester School of Medicine &DentistryImproved HSV Amplicon Vectors for Long-term Treatment of Parkinson’s Disease

Holly M. Brown-Borg, Ph.D.University of North DakotaAnti-oxidative Mechanisms and DamageResistance in a Mouse Model of DelayedAging

Michelle C. Carlson, Ph.D.Johns Hopkins UniversityRegular Mental Activity and CognitiveFunction in Older Adults

Monique M. Cherrier, Ph.D.University of WashingtonAndrogen Effects on Cognition in HealthyOlder Men

Jeff C. Falcone, Ph.D.University of LouisvilleVascular Myogenic Responses and Aging:Orthostatic Hypotension or Hypertension?

Deborah A. Ferrington, Ph.D.University of MinnesotaThe Role of the Proteasome ProteolyticPathway in Muscle Plasticity with Aging

Lee Goodglick, Ph.D.University of California, Los AngelesIdentification of an Antigen Associated withthe Pathogenesis of Giant Cell Arteritis

Jean X. Jiang, Ph.D.University of Texas Health Sciences Center atSan AntonioEstrogen and Intercellular Communication inBone Osteocytes

8

Ming-Tao Jiang, Ph.D.University of Wisconsin-MadisonProperties of Calcium Release Channels andTheir Regulation by ß-adrenergicStimulation in the Aged Rat Heart

Nori Kasahara, M.D., Ph.D.University of Southern CaliforniaInvestigating the Role of Klotho as aHumoral Factor Implicated in Age-relatedDisease Pathogenesis

Cathy Kotz, Ph.D.University of MinnesotaEffect of Age on Orexin-containing NeuralPathways

John Larson, Ph.D.University of Illinois at ChicagoNeurobiology of Aging in the MouseOlfactory System

Carl W. Luchies, Ph.D.University of KansasAge Effects on Postural ControlMechanisms: The Upper Extremities

Mathew Maurer, M.D.Columbia UniversityOrthostatic Hypotension and Falls inNursing Home Residents: Is Diastolic BloodPressure Changes More Predictive thanChanges in Systolic Blood Pressure?

Craig Neville, Ph.D.Massachusetts General HospitalMitigation of the Effects of Sarcopenia

David C. Paik, M.D.Columbia UniversityThe Non-enzymatic Nitration of Collagen inHuman Vascular Aging

Emily D. Richardson, Ph.D.University of Colorado, BoulderVisual Attention Training for At-risk OlderDrivers: A Pilot Intervention

Bart Rypma, Ph.D.University of PennsylvaniaNeural Correlates of Age-related Differencesin Working Memory

Stuart N. Seidman, M.D.Columbia UniversityTestosterone and Depression in Men

Caryl E. Sortwell, Ph.D.Rush-Presbyterian-St. Luke’s Medical CenterTrophic Inhibition of Apoptosis inMesencephalic Grafts to Aged Rats

Michael J. Toth, Ph.D.University of VermontSkeletal Muscle Protein Metabolism in HeartFailure Patients

Scott D. Webster, Ph.D.University of California, IrvineAmyloid Phagocytosis in Microglial:Contributions to Alzheimer’s Pathogenesis

1998 GranteesStacey M. Anderson, M.D.University of VirginiaAltered Regulation of Human GrowthHormone Secretion in PostmenopausalEstrogen Deficiency

Katrin Andreasson, M.D.Johns Hopkins University School of MedicineFunction of Cyclooxygenases in NeuronalInjury

Ben A. Bahr, Ph.D.University of Connecticut School of PharmacyInfluences of Aging Processes on GlutamateReceptor Modification and Regulation in aModel System

Partha P. Banerjee, Ph.D.Johns Hopkins University School of Hygiene &Public HealthRoles of Androgen and Estrogen in Age-dependent Development of ProstaticIntraepithelial Neoplasia and ProstateCancer in Brown Norway Rat

Alexandra L. Basolo, Ph.D.University of Nebraska-LincolnPleiotropic Effects of a Gene DeterminingAge and Size at Sexual Maturation

Maria L. Burgess, Ph.D.University of IllinoisIntergrin Expression and Second Signalingin the Adaptation of Cardiac Fibroblasts toAdvancing Age

Noel Y. Calingasan, D.V.M., Ph.D.Burke Medical Research InstituteA Test of How Aging Alters the Interactionbetween Oxidative Stress and NutritionalDeficit

Susana T.L. Chung, Ph.D.Indiana UniversityOptimizing Peripheral Reading Speed inOlder Americans with Age-relatedMaculopathy

Nicola S. Clayton, Ph.D.University of California, DavisThe Role of Brain Estrogens in Age-inducedMemory Loss: A New Animal Model

Igor M. Dozmorov, Ph.D.University of MichiganAntagonistic Interactions Among T-cellSubsets and Age-associatedImmunodeficiency

Narayanasamy Elango, Ph.D.University of Texas Health Science Center atSan AntonioDifferentiation of Bone Marrow OsteoblastProgenitor Cells: Analysis of GeneticDeterminants of Age-related Bone Loss

Andrea C. Gore, Ph.D.Mount Sinai School of MedicineNeuroendocrine Control of ReproductiveAging

Lynn Harrison, Ph.D.Louisiana State University Medical CenterInvestigation into the Role of Nuclear andMitochondrial DNA Damage in CellularSenescence

Kristine Krajnak, Ph.D.University of KentuckyEffects of Aging and Estrogen on 5HTNeural Activity and its Regulation ofActivity/Rest Rhythms

Valter D. Longo, Ph.D.University of Southern CaliforniaIdentification of Chronological LongevityAssurance Genes in Yeast

Lisa M. Miller, Ph.D.Albert Einstein Center for SynchrotronBiosciencesUnderstanding the Chemical Composition ofOsteoarthritic Bone

Thomas J. Montine, M.D., Ph.D.Vanderbilt UniversityLipid Peroxidation and APOE in Alzheimer’sDisease

Susumu Mori, Ph.D.Johns Hopkins UniversityBrain Fiber Tracking in Alzheimer’s Diseaseby Magnetic Resonance Imaging

Shin Murakami, Ph.D.University of Colorado, BoulderMolecular Mechanisms for Regulation ofLifespan and Increased Resistance toEnvironmental Stresses in C. elegans

Daniel A. Peterson, Ph.D.Salk Institute for Biological StudiesPrevention of Neuronal Cell Death in theEntorhinal Cortex

Blanka Rogina, Ph.D.University of Connecticut Health CenterCloning Two Genes with Different Regulationof Expression during Aging

Edward M. Schwarz, Ph.D.University of RochesterGene Therapy for Arthritis in the hTNF ß-Transgenic Mouse

Mary Seeger, Ph.D.Rockefeller Universityß-Secretase Cleavage of Alzheimer AmyloidPrecursor Protein in Yeast

Christian Sell, Ph.D.Allegheny University of the Health SciencesThe Role of Phosphatidylinositol 3-kinase inCellular Senescence

Jie Shen, Ph.D.Harvard UniversityFunctional Characterization of Presenilin-1Wild-type and Mutant Alleles in Mice

Pamela E. Souza, Ph.D.University of WashingtonUse of New Hearing Aid ProcessingStrategies by Elderly Adults

Mary A. Whooley, M.D.University of California, San FranciscoEstrogen Therapy and Depression in ElderlyWomen

1997 GranteesRobert D. Blank, M.D., Ph.D.The Hospital for Special SurgeryGenetics of Bone Mineral Content andQuality in Inbred Mice: Analysis of theHcB/Dem Recombinant Cogenic Strain Set

Cheong-Hee Chang, Ph.D.University of MichiganRegulation of IL-4 Production and its Rolein Aging

Robert F. Clark, Ph.D.Meharry Medical CollegeCharacterization of the Drosophila PresenilinGene

Lisa Tabor Connor, Ph.D.Boston University School of MedicineModulators of Lexical Retrieval Failure inOld Age

Timothy E. Curran, Ph.D.Case Western Reserve UniversityEvent-related Potentials of SensoryUnderload

Adriana Ferreira, M.D., Ph.D.Northwestern UniversityRegulation of Neuronal Kinase Activity by ß-Amyloid

Roger A. Fielding, Ph.D.Boston UniversityA Comparison of Progressive ResistanceTraining and High Velocity Muscle PowerTraining on Changes in Muscle Strength,Histology and Function in Frail OlderWomen

Mary Kay Francis, Ph.D.Allegheny University of the Health SciencesEPC-1 Expression and Aging: Effect onProliferation

Katsutoshi Furukawa, M.D., Ph.D.University of KentuckyFunctions of Presenilin Mutations in IonHomeostasis of Neuronal Cells

Jeffrey M. Hausdorff, Ph.D., MSMEBeth Israel Deaconess Medical Center/HarvardMedical SchoolFall Risk Assessment: A Prospective Studyof the Relationship between Gait Instabilityand Falls in the Elderly

Chun Huang, Ph.D.Hawaii Osteoporosis FoundationThe Impact of Osteoporotic Fractures onPhysical Function and Quality of Life Amongthe Elderly

Michael Jakowec, Ph.D.Parkinson’s InstituteThe Molecular Mechanisms UnderlyingEnhanced Sensitivity to MPTP in OldSquirrel Monkeys

9

Dean Kellogg, Jr., M.D., Ph.D.University of Texas Health Science Center atSan AntonioEffects of Reproductive System Aging onEndothelial Mechanisms of Vasoconstrictionand Vasodilation in Women

Daniel E. Lieberman, Ph.D.Rutgers UniversityEffects of Age and Exercise on Cortical BoneGrowth and Porosity

Ravindra P. Misra, Ph.D.Medical College of WisconsinMolecular Mechanism of Cell Activation byCalcium-containing Crystals

Mariana N. Nikolova-Karakashian, Ph.D.Emory UniversitySphingolipid Metabolism and Signaling inAged Male Rats: Relation to InflammatoryResponse and Regulation of Cell Growth

Sergey V. Nuzhdin, Ph.D.University of California, DavisThe Genetic Basis of Modification ofLifespan by an Individual’s Life History inDrosophila melanogaster

Junko Oshima, M.D., Ph.D.University of WashingtonConsequences of Werner Helicase GeneMutations on Expression of its mRNA andProtein

Joseph P. Pierce, Ph.D.Cornell University Medical CollegeNeuroanatomical Alterations in HippocampalPathways Associated with Learning andMemory Deficits in Aged Rats

Domenico Pratico, M.D.University of PennsylvaniaIsoprostanes, Oxidative Damage andAlzheimer’s Disease

Tracy G. Ram, Ph.D.Washington State University School ofBiological ScienceParacrine Action of Heregulins in the AgedMammary Gland

Cynthia Sites, M.D.University of VermontHormone Replacement Therapy andMetabolic Cardiovascular Risk

Nikolai Timchenko, Ph.D.Baylor College of MedicineStudies of the Molecular Basis for Loss ofRegenerative Capacity with Age-effect ofAging on C/EBP Alpha Mediated Control ofLiver Proliferation

Qi-hui Zhai, M.D., M.Sc.Medical College of OhioTumor Necrosis Factor in Cerebral Ischemiain Aged Rat

1996 GranteesNamanjeet Ahluwalia, Ph.D.Pennsylvania State UniversityPlasma Transferrin Receptors in the Elderlyas a Biomarker for Iron Deficiency:Establishing Normative Range and Cut-off

Dora Monica Berman, Ph.D.University of Maryland, BaltimoreCellular Mechanisms Underlying VisceralObesity in Postmenopausal Women: Effectsof Weight Loss

Diane M. Biskobing, M.D.Emory UniversityPrevention of Bone Resorption ThroughInhibition of Osteoclast Activity

Abraham Brown, Ph.D.Burke Medical Research InstituteRequirement for Membrane Association inthe Processing of Alzheimer’s PrecursorProtein by ß-secretase

Mary Patricia Corr, M.D.University of California, San DiegoCD1-mediated Regulation of T-cell EffectorFunction Using Gene Therapy

Rebecca L.W. Corwin, Ph.D.Pennsylvania State UniversityInfluence of Serotonin on Nutritional Statusin Aging

Matthew P. Frosch, M.D., Ph.D.Harvard Medical SchoolTransgenic Mouse Models for Early-OnsetAlzheimer’s Disease

Marc J. Glucksman, Ph.D.Mount Sinai School of MedicineFunctional Analyses of ß-Secretase(EP2415) in Alzheimer’s Disease

Patrick R. Hof, M.D., Ph.D.Mount Sinai School of MedicineRetinal Ganglion Cell Vulnerability in a Non-human Primate Model of Glaucoma

Karen Hubbard, Ph.D.City College of City University of New YorkPost-transcriptional Processing in CellularAging

Gursurinder P. Kaur, Ph.D.Temple University School of MedicineGenetics of Cell Senescence: Mapping ofCellular Senescence Genes on HumanChromosomes

Ichiro Kawachi, M.D., Ph.D.Harvard University School of Public HealthSocial Networks and Healthy Aging: AProspective Study

Evan T. Keller, D.V.M., Ph.D.East Virginia Medical SchoolAndrogen’s Effect on Interleukin-6Expression in Bone Cell Lines: Developing aMolecular Model for Osteoporosis

Virginia B. Kraus, M.D., Ph.D.Duke University Medical CenterRegulation of Metalloproteinases inOsteoarthritis

William T. Lee, Ph.D.David Axelrod InstituteThe Relationship between Memory TLymphocytes and Aging

Xipu Liu, M.D., Ph.D.Allegheny University of the Health SciencesRPE-controlled Choriocapillary EndothelialApoptosis: Relevance of ChoriocapillaryAtrophy in Age-related MacularDegeneration

Laura J. Mauro, Ph.D.University of Minnesota Medical SchoolParathyroid Hormone Regulation of a BoneTyrosine Phosphatase

Daniel Promislow, Ph.D.University of GeorgiaThe Effect of Retroviral-like Elements onAge-specific Mortality Rates

Jack T. Rogers, Ph.D.Harvard Medical SchoolAmyloid Precursor Protein mRNATranslation by Interleukin-1 and Alzheimer’sDisease

William A. Sather, Ph.D.University of Colorado Health Sciences CenterMolecular Composition of Neuronal CalciumChannels during Aging

Biao Shi, Ph.D.University of California, DavisAltered PI/PKC Signaling Pathway in AgedHuman Keratinocytes

Teresa Sobreviela, M.D., Ph.D.Rush-Presbyterian-St. Luke’s Medical CenterNGF Transport and trk Expression in AgedRat Towards a Novel Therapy for Age-relat-ed Cognitive Decline

Hinrich Staecker, M.D., Ph.D.Albert Einstein College of MedicinePrevention of the Loss of Auditory Neuronsin a Mouse Model of Presbycusis (C57B1)Strain by Neurotrophin-3 (NT-3Administration to the Inner Ear via a ViralVector [HSV Nt31ac])

Wenn H. Sun, Ph.D.Northwestern UniversityMolecular Mechanisms of Age-associatedInterleukin-6 Dysregulation in Post-menopausal Osteoporosis

Mark Tatar, Ph.D.University of MinnesotaMapping Genes for Mortality withTransposable Element Markers in Drosophilamelanogaster

Darryl G. Thelen, Ph.D.Hope CollegeMechanisms of Balance Recovery duringFalls: Age Effects

Huaxi Xu, Ph.D.Rockefeller UniversityRegulation of Alzheimer ß-AmyloidMetabolism by Signal Transduction

1995 GranteesJohn M. Abrams, Ph.D.University of Texas Southwestern MedicalCenterApoptosis and Aging in Drosophila

Michael E.T.I. Boerrigter, Ph.D.Harvard Medical SchoolDNA Repair and Mutations in Relation toAging in a New LacZ Plasmid-basedTransgenic Mouse Model

Richard M. Cawthon, M.D., Ph.D.University of UtahGenetic Variation at Antioxidant Loci, AgeUpon Diagnosis of First Tumor, and HumanLongevity

Beth Ann Derfus, M.D.Medical College of WisconsinPrevention of the Destructive CalciumCrystal Arhritides of Aging

Mark D’Esposito, M.D.University of PennsylvaniaWorking Memory in Normal Human Aging

Tekum Fonong, Ph.D.University of Maryland, BaltimoreLow Levels of Energy Expenditure in OlderAfrican-American Women: A PredisposingFactor in the Development of Obesity?

Sally R. Frenkel, Ph.D.New York University School of MedicineThe Effects of Nitric Oxide on Cartilage InVitro and In Vivo: Implications for Arthritis

Luc E. Gosselin, Ph.D.State University of New York at BuffaloAge-associated Susceptibility to MuscleInjury: Relationship to Muscle Stiffness andCollagen Cross-linking

Shelley L. Halpain, Ph.D.University of VirginiaAging and Neural Plasticity: Regulation ofCytoskeletal Proteins

Stephen L. Helfand, M.D.University of Connecticut Health CenterControl of Gene Expression during Aging

Jody L. Jensen, Ph.D.University of OregonBiomechanical Correlates of Age-relatedChanges in the Neural Control of Balance

Richard S. Jones, Ph.D.Southern Methodist UniversityTelomere Organization and Aging

Kathleen K. Kaysinger, Ph.D.Carolinas Medical CenterInteractions of Aging and Estrogen onOsteoblast Function

Lei Li, Ph.D.University of Texas M.D. Anderson CancerCenterAnalysis of Nucleotide Excision RepairDefect in Hutchinson-Gilford Progeria

R. Lee Mosley, Ph.D.University of Michigan Medical CenterFrequency and Expansionary Potential ofPost-thymic T Stem Cells from Aged Mice

10

Karen Diane Parfitt, Ph.D.Pomona CollegeChanges with Aging in Cyclic AMP-depend-ent Synaptic Transmission and SynapticPlasticity in Rat Hippocampus

Jharna Ray, Ph.D.Cornell UniversityAge-related Alteration in Retinal PigmentEpithelial Metabolism - Significance to Age-related Macular Degeneration

G. William Rebeck, Ph.D.Harvard Medical SchoolAnalysis for ApoE Mutations Affecting theRisk of Alzheimer’s Disease

Michael Sierks, Ph.D.University of Maryland, BaltimoreArtificial Antibodies for Diagnosis andTreatment of Alzheimer’s Disease

John R. Silber, Ph.D.University of WashingtonConsequences of Age-dependent Loss of theDNA Repair Protein O6-Methylguanine-DNAMethlytransferase in Human Brain

Mark A. Smith, Ph.D.Case Western Reserve UniversityMarkers of Oxidative Stress in Aging andNeurodegenerative Disease

J. Andrew Taylor, Ph.D.Harvard Medical SchoolEffect of Age and Hypertension onBaroreflex-mediated Autonomic Outflow

Guochuan Tsai, M.D., Ph.D.Harvard Medical SchoolA Pilot Study of D-cycloserine in Alzheimer’sDisease

Christopher H. van Dyck, M.D.Yale University School of MedicineMotor Correlates of Striatal DopamineTransporter Binding with [123I] ß-CITSPECT in Older Adults

Holly Van Remmen, Ph.D.University of Texas Health Science Center atSan AntonioProduction of Transgenic MiceOverexpressing Catalase and SuperoxideDismutase: A Model to Test the Free RadicalTheory of Aging

Richard E. White, Ph.D.Wright State University School of MedicineFemale Sex Hormones Prevent Age-inducedCardiovascular Dysfunction

1994 GranteesNir Barzilai, M.D.Albert Einstein College of MedicineAging Effects on Peripheral and HepaticGlucose Metabolism

Bysani Chandrasekar, D.V.M., Ph.D.University of Texas Health Science Center atSan AntonioModulation of Age-associated Loss inKidney Function by Calorie Restriction

Jonathan Day, Ph.D.Pennsylvania State UniversityPlasticity in the Aging Rat Hippocampus

Kottarappat Dileepan, Ph.D.University of Kansas Medical CenterProtective Effects of Heparin on VascularEndothelium

Pamela Fink, Ph.D.University of WashingtonT-cell Receptor Repertoire in CD4-CD8-Peripheral T-cells from Aged Mice

Lorise Gahring, Ph.D.University of UtahAge-related Changes in InflammatoryCytokine Expression in the Brain

Pamela Ann Gayheart, Ph.D.Medical College of PennsylvaniaThe Effects of Myocardial Ischemia on theCardiac Sympathetic Nervous System of theAging Heart

Garth Hall, Ph.D.University of PennsylvaniaPhosphorylation of Tau Protein in IdentifiedLamprey Neurons: A Cellular Model for theCytopathology of Alzheimer’s Disease

Ahmad Heydari, Ph.D.University of Texas Health Science Center atSan AntonioDoes Caloric Restriction Alter Transcriptionof Specific Genes at the Level ofTranscription Factors?

Eric Howard, Ph.D.University of Oklahoma Health Sciences CenterMatrix Metalloproteinases in Bone StromalCells

David Hurley, Ph.D.Tulane UniversityGrowth Hormone Releasing HormoneTranscriptional Regulation in Aging

Mary King, M.D.University of Connecticut Health CenterDo Postural Stability Limits Predict DynamicBalance Responses?

Qian Li, Ph.D.University of California, San FranciscoEffects of Aging on Voltage-dependent IonChannels in Myocardial Cells

Brian Richard MacDonald, M.B., CHB,Ph.D.Hospital of the University of PennsylvaniaA Cellular and Molecular Analysis ofOsteoblast Differentiation

Susan Marengo, Ph.D.Case Western Reserve University School ofMedicineStimulation of Growth of the ProstaticStroma by the Prostatic Epithelium: APossible Role for a Paracrine Pathway in theDevelopment of BPH

Daniel McCarty, M.D.Medical College of WisconsinA Quantitative Approach to InorganicPyrophosphate Metabolism

Skye McDougall, Ph.D.University of California, Los AngelesThe Role of TWIST in Controlling Type IICollagen Gene Expression in Chondrocytesand the Development of Osteoarthritis

Todd Morgan, Ph.D.Research University of Southern CaliforniaTGF-B1 and the Microglial Response toAging

Ramagopal Mudumbi, Ph.D.Veterans Affairs Medical Center, BoiseAging & Vascular Pharmacology ofAdenosine

Lauren Nathan, M.D.David Geffen School of Medicine at theUniversity of California, Los AngelesThe Effects of Conjugated Equine Estrogenson Coronary Blood Flow

Usha Ponnappan, Ph.D.University of Arkansas for Medical SciencesAging and Immune Function Role ofTranscription Factor NFKB

Marko Radic, Ph.D.Medical College of PennsylvaniaMolecular Basis for the Declining AntibodyResponse in Aging

May J. Reed, M.D.University of WashingtonAging, Caloric Restriction and WoundRepair

Chandar Singaram, M.B.University of Wisconsin-MadisonPathogenesis of Esophageal Dysmotility inthe Elderly

Charles Soparkar, M.D., Ph.D.Baylor College of MedicineEnhancing the Vascularization of OrbitalBone Substitutes: A Model for the Study ofChanges in Angiogenesis and Aging

Eugenia Spanoupolou, Ph.D.Rockefeller UniversityAge-related Loss of Immunoglobin Diversity& the Role of RAG-1 in the Bone MarrowLymphocytes of Elder Mice

Pericles Stavropoulos, Ph.D.Boston UniversitySynthesis of CuZnSOD Mimics as PotentialProbes of Age-related Oxidative Damage

Giulio Taglialatela, Ph.D.University of Texas Medical BranchNeurotrophins Rescue of Apoptotic NeuralCells

W. Robert Taylor, M.D., Ph.D.Veterans Affairs Medical Center, DecaturMechanisms of Age-related Impairment ofEndothelial Function

Jonathan Tilly, Ph.D.Johns Hopkins UniversityThe Molecular Basis of Female ReproductiveAging & Menopause

Elias Traboulsi, M.D.Johns Hopkins UniversityMapping the Gene(s) for Chronic OpenAngle Glaucoma (COAG)

Yaotang Wu, Ph.DChildren’s Hospital, Harvard Medical SchoolSolid State NMR Study of OsteoporoticBone

Donna Zimmaro Bliss, R.N., Ph.D.University of MinnesotaDietary Fiber Therapy for Fecal Incontinence

1993 GranteesDiana Bigelow, Ph.D.University of KansasEffects of Protein & Lipid Oxidation onIntracellular Calcium Regulation

Gregory Boyarsky, Ph.D.University of Texas Medical BranchRegulation of Intracellular pH in SingleSenescent Vascular Smooth Muscle

Judy Brunso-Bechtold, Ph.D.Bowman Gray School of Medicine atWake Forest UniversityEffects of Dietary Restriction onCerebovascular and Neural Aging

Mary Lou Caspers, Ph.D.University of Detroit-MercyInfluence of Estrogen on High AffinityCholine Uptake during Aging

Kathryn Clark, Ph.D.University of MichiganRegulation of Cytochrome c with OxidaseGene Expression in Aging Skeletal Muscle

Lucian Del Priore, M.D., Ph.D.Washington University School of MedicineTransplantation of Retinal PigmentEpithelium

Michele Didier, Ph.D.McLean HospitalMolecular Characterization of GlutamateReceptor Subunits in Neurodegeneration

Meika A. Fang, M.D.Veterans Affairs Medical Center, West LosAngelesThe Role of EGR-1 in Prostaglandin E2Mediated Signal Transduction andProliferation of Osteoblastic Cells

Thomas C. Foster, Jr., Ph.D.University of VirginiaNeurobehavioral Relations of the SenescentHippocampus

Barry Gumbiner, M.D.University of RochesterInsulin Signal Transduction in Aging

Eun-soo Han, Ph.D.University of Texas Health Science Center atSan AntonioEstrogen-dependent Gene Expression in theAging Brain

Robert H. Helfert, Ph.D.Southern Illinois University School of MedicineAlterations in the Synaptic Organization of theInferior Colliculus of Aging Fischer 344 Rats

Pamela L. Larsen, Ph.D.University of Missouri, ColumbiaA Molecular Genetic Approach to EfficientLife Maintenance

11

Edward J. Lesnefsky, M.D.Case Western Reserve UniversityIschemic Injury in the Aging Heart

Victoria Lundblad, Ph.D.Baylor College of MedicineCharacterization of an Alternate Pathway forTelomere Maintenance and its Role inCellular Senescence

Marco Marcelli, M.D.Baylor College of MedicineEstablishment of an Experimental Model toStudy the Development of HormoneUnresponsive Prostate Cancer

Geraldine M. McCarthy, M.D.Medical College of WisconsinCalcium-containing Crystal DepositionArthritis and Aging

Laurie McCauley, Ph.D., DDSUniversity of MichiganAging and Parathyroid Hormone (PTH)Function: Effects of Estrogen on PTHReceptors in Bone

Daniel Muller, M.D.University of WisconsinAging Calorie Restriction and the ImmuneResponse to Viral Infection

Mohammad A. Pahlavani, Ph.D.University of Texas Health Science Center atSan AntonioDoes Caloric Restriction and/orDehydroepiandrosterone Therapy Alter theAge-related Decline in HSP 70 Expression inLymphocytes?

David Roth, Ph.D.University of Colorado Molecular Mechanisms for AlteredAdrenergic Responses during Aging: Effectsof Chronic Dynamic Exercise on CardiacSignal Transduction

Alan R. Shuldiner, M.D.Johns Hopkins UniversityDuplication Scanning of Chromosome21g22 in Alzheimer’s Disease

Luis Felipe Sierra, Ph.D.Medical College of PennsylvaniaTesting the Role of Cysteine Proteinases inthe Process of Aging

Ray Thweatt, Ph.D.University of Arkansas for Medical SciencesCharacterization of Novel GenesOverexpressed in Senescent HumanFibroblasts

Wilma Wasco, Ph.D.Massachusetts General HospitalAnalysis and Expression of Human AmyloidPrecursor-like Protein 2 (APLP2) GeneTranscripts in Alzheimer’s Disease andNormal Brains

Huachen Wei, Ph.D.University of Alabama, BirminghamOxidative DNA Damage and Cerebral Aging

David Wilson, Ph.D.University of MiamiCan Aging and Mortality be Reduced byBlocking the Function of Particular GenesLate in Life?

Jeffrey Zachwieja, Ph.D.Washington University School of MedicineRole of Glutamine in Skeletal Muscle ProteinSynthesis: Is There an Age-related Effect?

Michael Zagorski, Ph.D.Case Western Reserve UniversitySequence Specific pKa Measurements of theAmyloid ß-Peptide Found in Alzheimer’sDisease

1992 GranteesNancy L. Baenziger, Ph.D.Washington University School of MedicineRelationship of Bradykinin ReceptorExpression to Cellular Senescence in an InVitro Model of Aging

Neil C. Binkley, M.D.University of Wisconsin-MadisonEffect of Interleukin-6 on Bone of Middle-aged and Old Rhesus Monkeys

John N. Buchholz, Ph.D.University of California, Irvine College ofMedicineEffect of Age on Control of NorepinephrineRelease

Jorge A. Busciglio, Ph.D.Children’s Hospital, BostonA Human Cortical Culture System as aModel for Alzheimer’s Disease

Joseph M. Capasso, Ph.D.New York Medical CollegeMechanical Cell Death Contributes to theDevelopment of Heart Failure in the Aged

Dean E. Dluzen, Ph.D.Northeastern Ohio UniversitiesAge-related Changes in Olfactory BulbNoradrenergic System: Implications ofNeurochemical Correlates of OlfactoryMemory-recognition Processes

Nejat K. Egilmez, Ph.D.McClellan Memorial Veterans Affairs HospitalIdentification and Characterization of Genesthat Modulate Lifespan in Caenorhabditiselegans

Mona M. Everett, Ph.D.University of Texas Health Science Center atSan AntonioTGF-ß Family Proteins and Cultured BoneMarrow Stromal Cells from Mature andAging Rats

Ronaldo P. Ferraris, Ph.D.University of Medicine & Dentistry of NewJerseyEffect of Age on Site Density of Intestinal D-glucose Transporters

Nestor F. Gonzalez-Cadavid, Ph.D.Harbor/University of California, Los AngelesMedical CenterThe Role of Aging in Erectile Dysfunction:Assessment of the Nitric Oxide Cascade inthe Aged Rat Penis

Marcia N. Gordon, Ph.D.University of Southern CaliforniaMicroglial Responses to Injury in Aging Brain

Joyce B. Harp, M.D.Emory University School of MedicineThe Renin-Angiotensin System in AdiposeTissue from Aging SpontaneouslyHypertensive Rats

Stephen L. Helfand, M.D.University of Connecticut Health CenterRegulation of Gene Expression during Aging

Lenore Holte, Ph.D.Syracuse UniversityThe Effects of Aging on Multi-frequencyTympanograms

Joel Horwitz, Ph.D.Medical College of PennsylvaniaPhosphatidylcholine Hydrolysis in the AgingRat

Bradley T. Hyman, M.D., Ph.D.Massachusetts General HospitalAre Nitric Oxide Synthase Neurons Sparedin Alzheimer’s Disease?

Philip E. Keeting, Ph.D.West Virginia UniversitySteroid Hormone Effects on HumanOsteoblastic Cell Interleukin-1 Production

Regina A. Kreisle, M.D., Ph.D.Purdue UniversityInvestigation of Age-related Changes inAngiogenesis Using an IntradermalAngiogenesis Assay in Mice

Bruce S. Kristal, Ph.D.University of Texas Health Science Center atSan AntonioOxidant-induced Repression ofMitochondrial Transcription: Testing thePredictions of the Free Radical and FreeRadical/Glycation Theories of Aging

Annette T. Lee, Ph.D.Picower Institute for Medical ResearchAge-related DNA Mutations of the Integrated1acI Gene in Transgenic Mice

Kathy Magnusson, D.V.M., Ph.D.Colorado State UniversityAge-related Changes in the Function ofExcitatory Amino Acid Receptors

Margaret K. McLaughlin, Ph.D.Children’s Hospital Medical Center, CincinnatiInteraction between Age and OvarianHormones on Resistance Artery Function

Estela E. Medrano, Ph.D.University of Cincinnati College of MedicineCellular, Biochemical and MolecularCharacterization of the Aging Melanocyte fromHuman Adult Skin: A Preliminary Approach

Keith C. Meyer, M.D.University of WisconsinImmunologic Changes in the Aging HumanLung

Dorabeth Parsons, Ph.D.University of ColoradoHormonal and Cellular Response to HeavyResistance Exercise in the Elderly

Kathryn V. Porrello, Ph.D.Doheny Eye InstituteRetinal Cytoskeletal Alterations in Aging andin Alzheimer’s Disease

Karen M. Prestwood, M.D.University of Connecticut Health CenterThe Relationships of Bone Turnover andBone Loss in Women 70 Years and Older

Julio A. Rimarachin, M.D.Cornell University Medical CollegeAge-related Arterial Intimal Hyperplasia

Ann K. Rosenthal, M.D.Medical College of WisconsinAging, TGF ß and CPPD Crystal DepositionDisease

Alan R. Salkind, M.D.University of Mississippi Medical CenterHuman Aging and Leukocyte Senescence

David R. Sell, Ph.D.Case Western Reserve UniversityPentosidine as a Biomarker for CellularAging of Human Skin Fibroblasts in Culture

Ram K. Sihag, Ph.D.Harvard Medical SchoolRole of Phosphorylation in the Dynamics ofBrain Spectrin in Aging Neurons

Julie K. Staley, Ph.D.University of Miami School of MedicineCharacterization of the Galanin Receptor inthe Human Brain Throughout the Lifespanand in Dementia

Henri Tiedge, Ph.D.Mount Sinai School of MedicineDendritic Protein Synthesis in the Aging RatBrain

Danny F. Watson, M.D., Ph.D.Wayne State University School of MedicineCytoskeletal Proteins of the Aging Brain

Jacek M. Witkowski, M.D., Ph.D.University of MichiganNew Subsets of T-cells in Old Mice -Differential Expression of P-glycoprotein

1991 GranteesStephen E. Alway, Ph.D.Ohio State UniversityEffects of Aging on Regulation of Overload-induced New Muscle Fiber Formation andMyosin Expression

Mariann Blum, Ph.D.Mount Sinai School of MedicineThe Role of EGF and bFGF Gene Expressionin the Maintenance and Neurodegenerationof Mesostriatal Dopamine Neurons

Patsy M. Brannon, Ph.D.University of ArizonaAging, Malnutrition and Pancreatic Function

Edith A. Burns, M.D.Sinai-Samaritan Medical CenterThe Role of T-cell and Accessory Cell-derived Cytokines in the Decreased SpecificHumoral Immune Response of Aging

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Sherry Bursztajn, Ph.D.Mailman Research Center, BostonExpression of Calcium-activated NeutralProteases in an Age-related Model of SpinalCord Degeneration

Greg D. Cartee, Ph.D.University of Wisconsin-MadisonMechanisms of Altered Glucose Metabolismwith Chronic Growth Hormone Treatment inMature, Middle-aged and Old Rats

Jane Reichert Clements, Ph.D.Texas A & M UniversityAge-related Changes in Excitatory AminoAcid Neurotransmission within theSubstantia Nigra

Robert A. Colvin, Ph.D.Ohio University College of Osteopathic MedicineNa/Ca Exchange and Brain Aging

Perry L. Colvin, Jr., M.D.Bowman Gray School of Medicine at WakeForest UniversityAcclimation to Dietary Cholesterol in Macacafascicularis

Robert E. Corin, Ph.D.College of Staten Island, City University of NewYorkCloning of GH-induced AntiproliferativeGenes during Terminal Differentiation

Isabelle (Reveillaud) Draper, Ph.D.Linus Pauling Institute, Palo AltoDevelopment of Transgenic Animals forAging Research: Introduction of AntioxidantGenes in Drosophila

Catherine E. DuBeau, M.D.Harvard Medical SchoolA Simplified Diagnostic Strategy for BenignProstatic Hypertrophy in Elderly Men

Janet M. Dubinsky, Ph.D.University of Texas Health Science Center atSan AntonioRole of Intracellular Calcium Levels inTrophic Factor-dependent Survival of CentralCholinergic Neurons

John Fox, Ph.D.Tulane University Medical CenterRegulation of Parathyroid Hormone in AgingRats

Ruby Ghadially, Ph.D.University of California, San FranciscoFunctional and Structural Alterations inAged Epidermis

Mark D. Grabiner, Ph.D.The Cleveland ClinicRelationship between Trunk Biomechanicsand Falling Behavior in the Elderly

Brenda Hall, Ph.D.Mount Sinai Medical CenterStudy of Frequency of Somatic Mutation inV Gene Encoding Autoantibodies duringAging

Marilyn Hartman, Ph.D.University of North CarolinaAge Differences in Selective Attention andMemory

Monte V. Hobbs, Ph.D.Scripps Clinic, La JollaSubsets of CD4+ T-cells in Aging Mice

Laura J. Jenski, Ph.D.Indiana UniversityOmega-3 Fatty Acids in Plasma andMitochondrial Membranes of Aging T-lymphocytes

Rodrigo O. Kuljis, M.D.University of IowaCytochemical Substrate of the VisualImpairment in Aging and in Alzheimer’sDisease

Anat A. Lev, Ph.D.Massachusetts General HospitalCloning of Ciliary Neurotrophic Factor andCharacterization of its Role in Aging andAge-related Disorders of the HumanNervous System

Alice C. Levine, M.D.Mount Sinai Medical CenterIn Vitro Studies on the Pathogenesis ofBenign Prostate Hyperplasia

Richard J. McCormick, Ph.D.University of WyomingMyocardial Collagen Gene Expression andExtracellular Matrix Characteristics of theRat Heart: Effects of Aging and ExerciseTraining

Charles V. Mobbs, Ph.D.Rockefeller UniversityA Neuroendocrine Mechanism PotentiallyMediating Effects of Dietary Restriction andGlucose on Age-correlated Pathologies

Douglas C. Powers, M.D.Saint Louis University School of Medicine Age-related Changes in Lymphocyte Adhesion

Mitch O. Rotenberg, Ph.D.Medical College of PennsylvaniaIsolation of cDNAs Encoding Human,Senescence-specific Anti-proliferativeFactors: A Novel Approach

Janet Rubin, M.D.Emory University School of MedicineEffects of Time-varying Electric Fields onBone Resorption and Formation

Joseph A. Schauerte, Ph.D.University of MichiganRole of Charge-transfer in Ligand Bindingand Chemical Oxidation

Andrew J. Silver, M.D.Saint Louis University School of MedicineAn Animal Model of Age-related Hypodipsia

Thomas M. Skeehan, M.D.Penn State Milton S. Hershey Medical CenterMechanisms of Anesthetic-inducedMyocardial Depression in Senescence: InVitro and Ex Vivo Studies

Dan F. Spandau, Ph.D.Indiana University School of MedicineAnti-oncogene Expression during TerminalDifferentiation and Cellular Senescence

Timothy L. Denton, Ph.D.Andrus Gerontology Center at the University ofSouthern CaliforniaExpression of BDNF in the Aging Brain

Henry J. Donahue, Ph.D.Stony Brook Health Sciences Center, StateUniversity of New YorkAge-related Changes in Bone Cell SignalTransduction

Kevin Flurkey, Ph.D.Boston University School of MedicineThe Cellular Basis for Age-related Change inActivation of Helper T Lymphocytes

Changiz Geula, Ph.D.Beth Israel Hospital, BostonEffects of Aging on the MorphometricParameters of Cholinergic Neurons of theNucleus Basalis of Meynert in Man

F. Michael Gloth, III, M.D.Johns Hopkins University School of MedicineVitamin D Deficiency in Homebound Elderly

Steven R. Hager, Ph.D.Medical College of WisconsinCellular Mechanisms of Age-related InsulinResistance in Rat Muscle and Adipose Tissue

Seigo Izumo, M.D.Beth Israel Hospital, BostonMolecular Mechanisms of MyocardialSenescence: Role of Proto-oncogeneExpression

Li Li Ji, Ph.D.University of IllinoisAging and Antioxidant Enzymes: Adaptationto Chronic Exercise

Mirtha Kelijman, M.D.Saint Louis University School of MedicineSpontaneous Secretion of Growth Hormonein Aging Humans

Madeleine A. Kirchberger, Ph.D.Mount Sinai Medical CenterIs Increased Phosphoprotein PhosphotaseActivity a Possible Factor in DecreasedResponsiveness to ß Adrenergic Hormonesin Senescent Myocarium?

G. Gopal Krishna, M.D.Temple University School of MedicineEffect of Potassium Depletion on BloodPressure in Elderly

Robin J. Leach, Ph.D.University of Texas Health Science Center atSan AntonioRegulation of the Estrogen Receptor in anOsteoblast-like Osteosarcoma: A Model forOsteoporosis

Ruth Medina, Ph.D.Harvard Medical SchoolSystems for Degrading Abnormal Proteinsin Brain in Alzheimer’s Disease

Mervyn Monteiro, Ph.D.University of MarylandA Biochemical and Immunological Study ofNeurofilaments in Aging

Rama K. Nemani, Ph.D.Saint Louis University School of MedicineDecreased Renal Production of BiologicallyActive Vitamin D with Age

Janet S. Sunness, M.D.Johns Hopkins University School of MedicineRetinal Sensitivity Change as a Marker forDeveloping Subretinal New Vessel Membranesin Age-related Macular Degeneration

John P. Walsh, Ph.D.University of Southern CaliforniaAge-dependence of the ElectrophysiologicalResponse to Excitotoxity in the BasalForebrain

Christina Wang, M.D.Cedars-Sinai Medical CenterThe Effect of Aging on the Role of InsulinGrowth Factor I in TesticularSteroidogenesis in the Rat

Funmei Yang, Ph.D.University of Texas Health Science Center atSan AntonioMolecular Basis for the Age-modulatedCeruloplasmin Expression in Kidney

Judith I. Yannariello-Brown, Ph.D.University of Texas Medical BranchEffects of Aging on Circulating HyaluronateLevels and Liver Endothelial CellHyaluronate Receptor Function

Cho-yau Yeung, Ph.D.University of Illinois College of MedicineTransgenic Animal Models of Alzheimer’sDisease

1990 GranteesSid P. Bacon, Ph.D.Arizona State UniversityDetection of Amplitude Modulation in theElderly

Bula Bhattacharyya, Ph.D.University of IowaAge-related Alteration of NeuromuscularTransmission: Effect of Halothane

Paula Bickford-Wimer, Ph.D.University of Colorado Health Sciences CenterCerebellar Involvement in Age-relatedImpairments in Motor Learning

Gabriel H. Brandeis, M.D.Harvard Medical SchoolA Simplified Diagnostic Test forIncontinence in Frail Elderly Men

Judith Campisi, Ph.D.Boston University School of MedicineCellular Aging and Proto-oncogeneExpression

Ming L. Chen, Ph.D.Saint Louis University School of MedicineAge-related Changes in the Regulation ofRenal Ca-binding Protein by Vitamin D

Barbara A. Clark, M.D.Harvard Medical SchoolMechanisms of Secretion andPathophysiologic Consequences of ElevatedAtrial Natriuretic Peptide in the Elderly

David C. Dale, M.D.University of WashingtonHematopoietic Progenitors and Aging:Proliferative Response to HematopoieticGrowth Factors

13

Carol J. Phelps, Ph.D.Tulane University Medical CenterCatecholaminergic Neuron Plasticity in theAged Rat Brain

Raymond M. Quock, Ph.D.University of Illinois College of MedicineOpioid Analgesia and Brain OpoidRadioligand Binding in Senescent Rats

Jane F. Reckelhoff, Ph.D.University of Mississippi Medical CenterMechanisms of Age-dependent Change inRenal Protein Turnover in the Rat

Scott W. Rogers, Ph.D.Salk Institute for Biological Studies, San DiegoExcitotoxicity in RAT 2 Fibroblasts StablyExpressing a cDNA Encoding a Member ofthe Glutamate Receptor Family

Martin Sarter, Ph.D.Ohio State UniversityDisinhibition of Cortical Cholinergic Activityand Attenuation of Age-related AttentionalImpairments

Jacob J. Steinberg, M.D.Albert Einstein College of MedicineAlteration of DNA Binding Sites and Proteinsin Aging

Bruce R. Troen, M.D.University of MichiganRegulation of Expression of Cathepsin L

Alan Tucker, Ph.D.Colorado State UniversityThe Effects of Aging and Exercise onVascular Reactivity in the Isolated PerfusedRat Hindlimb

David S. Ucker, Ph.D.Medical Biology Institute, La JollaSusceptibility of T-cells to Activation-drivenCell Death: Aging-associated Changes andAutoimmunity

Molly S. Weiler, Ph.D.University of Wisconsin School of PharmacyMuscarinic Modulation of NeostriatalAcetylcholine Release during Senescence

William V. Williams, M.D.University of PennsylvaniaAutoimmunity and Aging: CyrokineInvolvement in the Development ofRheumatoid Sinovitis

John Ding-e Young, M.D. Ph.D.Rockefeller UniversityMolecular Mechanisms of Programmed CellDeath (Apoptosis)

1989 GranteesKevin J. Anderson, Ph.D.University of FloridaExcitotoxicity and NMDA Receptors in theAged Brain

John Aronson, Ph.D.Wistar InstituteEnhancer Sensitive Cell Lines for AgingStudies

Stephen Baumann, Ph.D.University of Texas Medical BranchThe Use of Magneto-encephalography toDetect Mild Alzheimer’s Disease

Xandra O. Breakefield, Ph.D.Eunice Kennedy Shriver Center, BostonAge-related Regulation of MonamineOxidase

Karen P. Briski, Ph.D.Washington State UniversityImmunologic and Biologic Potencies ofProlactin Hormonal Forms Synthesized byYoung and Old Rat Pituitary Glands

Donald M. Caspary, Ph.D.Southern Illinois University School of MedicineAge-related Changes in a Central AuditoryStructure: A Key to Presbycusis

William T. Cefalu, M.D.Bowman Gray School of Medicine at WakeForest UniversityThe Role of the Aging Process on InsulinReceptor Recycling In Vivo

Terriann Crisp, Ph.D.Northeastern Ohio UniversitiesAge-related Changes in Spinal Opiate-induced Analgesia

Susan Ettinger, Ph.D.Cornell University Medical CollegeAge-associated Chromosomal Fragility inHuman Lymphocytes

Donna D. Flynn, Ph.D.University of Miami School of MedicineAge-altered M-1 Muscarinic Receptor Function

Joseph A. Gascho, M.D.Penn State Milton S. Hershey Medical CenterThe Effects of Aging on the VenodilatoryResponse to Nitroglycerine

Gabriel Gold, M.D.Mount Sinai Medical CenterInfluence of Age on Basal and ExerciseStimulated Atrial Natriuretic Hormone

Reuben Gonzales, Ph.D.University of TexasEffects of Aging on Glutamate ReceptorFunction

Susan Greenspan, M.D.Harvard Medical SchoolThe Role of Newly Discovered CoenzymePQQ in Age-related Dopamine Regulation

Sharon K. Inouye, M.D.Yale University School of MedicineAcute Confusional State in the HospitalizedElderly: Incidence, Risk Factors andComplications

S. Michal Jazwinski, Ph.D.Louisiana State University Medical CenterThe ß-Amyloid Gene of Yeast

Donald A. Jurivich, D.O.Northwestern University Medical CenterSignal Transduction during Heat Shock andSenescence

Frances M. Leslie, Ph.D.University of California, IrvineNeurotransmitter Correlates of SenescentMemory Decline

Scott L. Mader, M.D.Case Western Reserve UniversityEffect of Aging on Adrenergic Physiology inCultured Vascular Smooth Muscle Cells

Jeffrey N. Masters, Ph.D.University of Southern CaliforniaGlucocorticoids and the Aging Hippocampus

Roger B. McDonald, Ph.D.University of California, DavisEffect of Age and Gender on the NeuralControl of Pancreatic Function

Michael J. Meldrum, Ph.D.University of Florida College of PharmacyAlterations in Glutamate Release in Aging

Russell L. Moore, Ph. D.Penn State Milton S. Hershey Medical CenterAdaptation of Senescent Myocardium toTraining

William C. Orr, Ph.D.Southern Methodist UniversityThe Effects of Glutathione Peroxidase onAging in Transgenic Drosophila

Horace M. Perry, M.D.Saint Louis University School of MedicineInvolutional Osteoporosis, Osteoblast andOsteoclast Activity

John W. Rachow, M.D., Ph.D.University of Iowa College of MedicineThe Role of Matrix Vesicle Function inHerteroptic Ossification Following HipArthroplasty

Richard L. Riley, Ph.D.University of Miami School of MedicineRegulation of ß Lineage ImmunocyteDevelopment in Aging

Eugene L. Roberts, Jr., Ph.D.University of Miami School of MedicineIncreased Vulnerability of Aged Brain toAnoxia

Dorrie E. Rosenblatt, M.D., Ph.D.University of MichiganProtease Nexin I Binding: A BiochemicalMarker for Alzheimer’s Disease?

Robert D. Shaw, M.D.Veterans Affairs Medical Center, Northport, NYProlactin Rejuvenation of Aged MurineMucosal Immunity

J. David Sweatt, Ph.D.Baylor College of MedicineCholinergic and Noradrenergic Mechanismsin the Hippocampus: Possible MolecularLocus for Aging-related MemoryDysfunction

Mitchell S. Turker, Ph.D.University of Kentucky School of MedicineAn In Vitro Analysis of a MammalianHibernation Factor

Randall J. Urban, M.D.University of Virginia School of MedicineSex Steroidal Mechanisms Modulating FSHElevations in Healthy Men

Roy B. Verdery, M.D., Ph.D.Bowman Gray School of Medicine at WakeForest UniversityRole of Lipoproteins in Production of TumorNecrosis by Monocyte-Macrophage

Bryant Villeponteau, Ph.D.University of MichiganGenetic Markers of Aging andImmortalization

Hoau-yan Wang, Ph.D.Medical College of PennsylvaniaThe Effect of Age on Human Protein Kinase C

Zahra F. Zakeri, Ph.D.University of Medicine & Dentistry of NewJerseyStress Proteins and Stress Response inAging Tissues

1988 GranteesIna J. Amber, M.D.University of UtahEffects of Age on the Activation and CytoxicEffector Mechanisms of Macrophages

Rosemarie M. Booze-Aron, Ph.D.University of Kentucky Medical CenterInitiation and Maintenance of Neural Growthin Aging: Role of NGF

Connie W. Bales, Ph.D.Duke University Medical CenterVitamin D Metabolism: A Function of KidneyDonor Age

Margaret M. Baumann, M.D.Harvard Medical SchoolCellular Mechanisms of Incontinence in theElderly

Elizabeth S. Boylan, Ph.D.Queens College, City University of New YorkThe Control of Metastisis by Dietary Fat inAged Rats

Anne M. Cataldo, Ph.D.McLean HospitalMolecular Mechanisms of NeuronalProteolysis during Normal Aging and Late-onset Neurodegenerative Disease

James R. Connor, Ph.D.Pennsylvania State UniversityAluminum Access to the Brain: The Role ofthe Transferrin Receptor

Nazneen Dewji, Ph.D.University of California, San Diego School ofMedicineMolecular Studies of Disorders ofAccelerated Aging

Peter D. Gorevic, M.D.State University of New York, Stony BrookAmyloid and Aging: Abnormalities in theProcessing of Autologous Proteins

Marilyn Gossman, Ph.D.University of Alabama, BirminghamRelationship of Strength, Muscle Length,Balance, and Gait Characteristics to Fallingin Elderly Women

14

Ernest R. Greene, Ph.D.Lovelace Medical FoundationAge-related Differences in Human RegionalBlood Flow

Margaret T. Hessen, M.D.Medical College of PennsylvaniaRole of Lymphokines in DecreasedLymphoproliferative Response of the Elderlyand Relation to Morbidity and Mortality

Martin I. Horowitz, Ph.D.New York Medical CollegeGlycation of Histones in the Aging Brain

Mark D. Johnson, Ph.D.Medical College of PennsylvaniaStimulus Response Coupling in the AgingVasculature

Judith A. Kiritsy-Roy, Ph.D.University of MichiganRole of Opioid Peptides & CorticotrophinReleasing Hormone to ModulateSympathetic Outflow & CardiovascularFunction during Aging Process of Rats

Daniel A. Kirschner, Ph.D.Boston Children’s Hospitalß-Amyloid of Alzheimer’s Disease: Assemblyand Stability

Dalane W. Kitzman, M.D.Duke University Medical CenterAge Relationships in Central & PeripheralCardiovascular Function during Rest andExercise in Normal Subjects

Gary Kochersberger, M.D.Buffalo Veterans Affairs Medical CenterThe Metabolic Effects of CalciumSupplementation in the Elderly

Deborah C. Mash, Ph.D.University of Miami School of MedicineAge-altered Neurotransmitter ReceptorArchitectonics

Vincent M. Monnier, M.D.Case Western Reserve UniversityStructure, Elucidation and Role of aBiological Marker for Aging

Robert W. Rees-Jones, M.D.Columbia UniversityCorrection of In Vitro Growth Defects ofWerner’s Syndrome Fibroblasts by GeneTransfer

Anthony C. Santucci, Ph.D.Bronx Veterans Affairs Medical CenterAn Examination of NGF’s Efficacy in Aged Rats

Jay S. Schneider, Ph.D.Hahnemann UniversityThe Effects of Age on Dopamine SystemRegeneration in a Rodent Model ofParkinsonism

Thomas Sorger, Ph.D.Wistar InstituteModulation of Human Vascular SmoothMuscle Cell Responses to Monocyte Factorsby n-3 Fatty Acids and DHEA

Andrea L. Spiering, Ph.D.Baylor College of MedicineEscape from Senescence: The SUSM-1 CellLine as a Model System

Gretchen H. Stein, Ph.D.University of ColoradoExpression of a Senescence-related Geneduring Cellular Aging

Michael K. Stock, Ph.D.Oregon Health & Science UniversityEffect of Prenatal Oxygen Exposure onGrowth, Metabolism, Aging and Longevityof Drosophila

Joyce S. Tenover, M.D., Ph.D.Harborview Medical Center, SeattleEffects of Testosterone Replacement inElderly Men

Nancy G. Weiland, Ph.D.University of MarylandNMDAS and GABA Receptors in AgingFemales

1987 GranteesVincent J. Aloyo, Ph.D.Medical College of PennsylvaniaAge-related Alteration of HypothalamicSerotonin Stimulus-secretion Coupling

Jeffrey Aron, M.D.Mount Zion Hospital, San FranciscoPhysiological Determinants of RestingEnergy Expenditure in the Elderly

Carol A. Barnes, Ph.D.University of ColoradoEffects of Aging on Sensory-motorInformation Processing Capabilities ofMammalian Association Cortex

Jerry G. Blaivas, M.D.Columbia University College of Physicians andSurgeonsUrodynamics of Aging

Terrence F. Blaschke, M.D.Stanford University Medical Centerß Blocker vs. Calcium Channel Blocker:Relative Incidence of Cognitive Dysfunctionand Depression in Elderly Patients

John F. Disterhoft, Ph.D.Northwestern University Medical SchoolMechanisms of Age-related Memory Deficits

Linda A. Dokas, Ph.D.Medical College of OhioNeurochemical Correlates of HippocampalAging

David N. Ernst, Ph.D.Scripps Clinic, San DiegoSynthesis and Activity of Interleukin-2 inAged Mice

James W. Gaubatz, Ph.D.University of South AlabamaDNA Repair of Proto-oncogenes during Aging

Alfred I. Geller, Ph.D.Massachusetts General HospitalStudies on Alzheimer’s Disease and LongTerm Memory Loss in the Hippocampus, InVivo, Using HSV-1 Vectors

Dick Greene, Ph.D.New Mexico Highlands UniversityAging and Human Regional Blood Flow

Margaret A. Griffin, M.D.Pettis Memorial Veterans Affairs HospitalA T-cell Biomarker of Cellular Aging

Jerome H. Herman, M.D.University of Cincinnati College of MedicineHealing of Osteoarthritic Cartilage byNd:YAG Laser Radiation

Andrew K.S. Ho, Ph.D.University of Illinois College of MedicineMolecular Mechanisms of MuscarinicAcetylcholine Receptor in Aging

Anne L. Hoff, Ph.D.State University of New York, Stony BrookThe Effects of Tricyclic AntidepressantMedication on Cognitive Functioning in theAged

Laura L. Mays Hoopes, Ph.D.Occidental CollegeDecreased DNA Methylation Capacity inAging Mouse Liver

Jeffrey N. Joyce, Ph.D.University of PennsylvaniaNeurotransmitter Alterations in Aged Striatum

Donald A. Kleinsek, Ph.D.Baylor College of MedicineGene Expression Studies of Cellular Aging InVitro

Melinda A. Lee, M.D.Oregon Health and Science UniversityRegulation of Hematopoiesis by MarrowStromal Cells: Age-related Changes

Timothy A. McCaffrey, Ph.D.Cornell University Medical CollegeAge and Smooth Muscle Proliferation:Potential Influence of PDGF-like Factors

David G. Morgan, Ph.D.University of Southern CaliforniaGene Expression in Alzheimer’s Disease

Jay S. Pepose, M.D.Washington University School of MedicineImmunological Studies of Age-relatedMacular Degeneration

K. Murali Krishna Rao, M.D.Duke University Medical CenterMechanisms of Cellular Senescence inLymphocytes and Neutrophils

Jo Anne Robbins, Ph.D.University of WisconsinSelected Aspects of Oral-pharyngealSwallowing in Normal Aging Adults

Steven H. Robison, Ph.D.University of VermontCharacterization of the DNA Repair Defect inFamilial Alzheimer’s Disease

Miriam Schweber, Ph.D.Boston University School of MedicineChromosome 21 DNA Determinations onAge-associated Dementias

Thomas B. Shea, Ph.D.Mailman Research Center, BostonInduction of Axonal Atrophy in CulturedNeuron Cells

Joe E. Springer, Ph.D.Hahnemann UniversityTransplantation of NGF-rich Tissue ProvidesTrophic Support for Damaged CholinergicNeurons

Einar Stefansson, M.D., Ph.D.Duke University Medical CenterSurgical Relocation of the Macula: A Treatmentfor Age-related Macular Degeneration

Trygve O. Tollefsbol, Ph.D.Duke University Medical CenterRNA Processing and Enzyme Induction inAging Using Cloned cDNA Probes

Nihal Tumer, Ph.D.Medical College of PennsylvaniaAge-related Changes in the Effect ofCirculating Catecholamines on the CardiacAdrenergic Neuroeffector Junction

Cheryl A. Walters, M.D.Cornell University Medical CollegeAge-related Antibody Kinetics of PolyvalentPneumococcal Vaccine

1986 GranteesGary Aston-Jones, Ph.D.New York UniversityPhysiological Properties of Cholinergic andNoradrenergic Cortical Afferent Neurons inBehaving Primates: Changes with Old Age

Cynthia M. Beall, Ph.D.Case Western Reserve UniversityAge and Adaptation to High Altitude Hypoxia

Paul E. Bendheim, M.D.New York State Institute for Basic ResearchScrapie as a Model for Alzheimer’s Disease:Purification & Characterization of a PutativeAmyloid Precursor Protein

Jesse M. Cedarbaum, M.D.Burke Rehabilitation Center, White PlainsEarly Signs of Cognitive Impairment inParkinson’s Disease and Normal Aging

Christopher K. Daniels, Ph.D.University of California, San Francisco Schoolof MedicineRegulation of the Intestinal ImmuneResponse in the Aged Rat

Ralph Dawson, Jr., Ph.D.University Florida College of PharmacyExcitotoxic Amino Acids and Neuronal Lossin the Aging Brain

Lawrence K. Duffy, Ph.D.University of AlaskaMonoclonal Antibodies to Age-relatedAbnormal Proteins

John Ellis, Ph.D.University of VermontSelective Regulation of CNS MuscarinicReceptors: Implications for Aging Research

Roger P. Farrar, Ph.D.University of TexasEffects of Exercise Upon Age-inducedDeficits in Neuronal Calcium Transport

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Paul G. FitzGerald, Ph.D.University of California, Davis School ofMedicineThe Role of Molecular & Cellular Aging inOcular Lens Opacification and Cataract

Ari Gafni, Ph.D.University of MichiganFunctional Interactions Among Enzymes inAging Muscles

James W. Gaubatz, Ph.D.University of South AlabamaDNA Damage during Aging of PostmitoticCells

Ronald H. Goldstein, M.D.Boston University School of MedicineActivation of Aged Vascular Smooth MuscleCells

Laura L. Mays Hoopes, Ph.D.Occidental CollegeMethylation of Single Copy Genes duringAging

Thomas E. Johnson, Ph.D.University of ColoradoMolecular Cloning of a Major GeneSpecifying Length of Life

Harvey S. Levin, Ph.D.University of Texas Medical BranchEvaluation & Outcome of SenescentForgetfulness

Michael J. Lichtenstein, M.D.Vanderbilt UniversityA Controlled Trial of an Exercise Program toImprove the Balance of Elderly Women

Victoria N. Luine, Ph.D.Hunter College, City University of New YorkEndocrine Influences on Aging of theForebrain Cholinergic System

Steven S. Matsuyama, Ph.D.West Los Angeles Veterans Affairs MedicalCenterMicrotubules & Alzheimer’s Disease

John E. Pintar, Ph.D.Columbia University College of Physicians andSurgeonsGrowth Factor Gene Expression in AgingRats

Martin P. Schweizer, Ph.D.University of VermontStudies of Cerebral Metabolism in the AgingRat Using NMR In Vivo

Harry B. Skinner, M.D., Ph.D.University of California, San FranciscoFinite Element Studies of the Below-kneeProsthesis

Nancy W. Stead, M.D.Medical College of GeorgiaDefective Mononuclear Cell Support ofErythropoiesis in Elderly

H. Lee Sweeney, Ph.D.University of TexasAging-related Alterations in CardiacContractile Protein Expression and Function

Trygve O. Tollefsbol, Ph.D.Duke University Medical CenterExpression of Enzyme Inductive Defects inImpaired Immunity of the Aged

Larry E. Tune, M.D.Johns Hopkins HospitalRegional Cerebral Glucose Metabolism &Response to Physostigmine in DementiaIllnesses

Steven Waller, Ph.D.University of South Dakota School of MedicineNicotinic Cholinergic Binding in PostmortemBrains of Demented Patients

Sharon E. Washington, M.D.Ohio State University HospitalIntestinal Physiology and EndocrineFunction with and without the Effect ofSomatostatin during Post-prandialHypotension in the Elderly

Steven G. Younkin, M.D., Ph.D.Case Western Reserve UniversityThe Basal Forebrain Cholinergic System inAging and Alzheimer’s Disease

Elizabeth M. Zelinski, Ph.D.University of Southern CaliforniaValidation of a Test Assessing Self-percep-tions of Memory in the Elderly

1985 GranteesJoshua E. Adler, M.D., Ph.D.Cornell University Medical CollegeAged Neurons: Deficits in Neural Plasticityat the Molecular Level

Michael J. Belman, M.D.City of Hope National Medical CenterExercise Intensity and Training Response inthe Elderly

Michael A. Casey, Ph.D.University of AlabamaAging in the Auditory System: The LateralSuperior Olivary Nucleus

Ian Creese, Ph.D.University of California, San DiegoRegulation of Dopamine Receptor TurnoverRates in Aging

Felix Friedberg, Ph.D.Howard University College of MedicineCalmodulin mRNA in Various Parts of theBrain in Aging

Naomi Kay Fukagawa, M.D., Ph.D.Massachusetts Institute of TechnologyGlucose and Fatty Acid Metabolism inAging: Effects of High-carbohydrate, High-fiber Diets and Brief Starvation

Ari Gafni, Ph.D.University of MichiganReversal of Age-related Effects in MuscleEnzymes

Raj Kumar, Ph.D.University of IllinoisC-Kinase in Senescence

Kasmierz Malinowski, Ph.D.Columbia University College of Physicians andSurgeonsAge-related Formation of AbnormalProteins: Investigation of Lens Tissue

Charles A. Marotta, M.D., Ph.D.Harvard Medical SchoolMolecular Studies on the Aging andAlzheimer’s Disease Brain

Richard A. Miller, M.D., Ph.D.Boston University School of MedicineAge-related Retardation in Stages of TLymphocyte Activation

Catherine Mytilineou, Ph.D.Mount Sinai School of MedicineTissue Culture Studies on the Aging ofCentral Nervous System CatecholamineNeurons

Howard J. Normile, Ph.D.Lafayette Clinic, DetroitRelation between Serotonin, Memory &Aging

James J. O’Leary, M.D., Ph.D.University of MinnesotaT-cell Surface Antigen Expression in Aging Man

Richard D. Olson, Ph.D.University of Washington School of MedicineMyocardial Function and Aging: Role ofOxygen Free Radicals and the GlutathionePathway

Norman W. Pedigo, Jr., Ph.D.University of KentuckyRegulation of Brain Muscarinic ReceptorSubtypes in Aging

Chandan Prasad, Ph.D.Louisiana State University School of MedicineCyclo (His-Pro) and Neuroleptic-inducedAnimal Model of Tardive Dyskinesia

William J. Rhead, M.D., Ph.D.University of Iowa College of MedicineThe Molecular Biology of Aging and LipidMetabolism in Human Fibroblasts

Mark Rosenthal, M.D.University of New MexicoDoes the Dawn Phenomenon Exist inNormal Elderly Subjects?

Henry Rothschild, M.D., Ph.D.Louisiana State University Medical CenterMolecular Biology of Aging

Daniel Rudman, M.D.Chicago Medical SchoolRenal Effects of Human Growth HormoneTherapy in Elderly, Hyposmatotropic Men

R.S. Sohal, Ph.D.Southern Methodist UniversityRelationship between DNA-repair,DNA-transcription and Aging

Marilyn L. Thoman, Ph.D.Scripps Clinic, San DiegoRestoration of Immune Function in the Agedwith Interleukin 2

Richard F. Thompson, Ph.D.Stanford UniversityCerebellar Mechanisms in Age Differences inAcquisition and Retention of the ClassicallyConditioned Eyelid Response in Rabbits

1984 GranteesItamar B. Abrass, M.D.Harborview Medical Center, SeattleMechanisms of Age-related Changes in ß-Receptor

Richard C. Adelman, Ph.D.University of MichiganMolecular Heterogeneity of Somatostatinduring Aging

Stephen P. Baker, Ph.D.University of FloridaAge-related Changes in the CardiacCholinergic System

Douglas E. Brash, Ph.D.Yale University School of MedicineConstruction of Chimeras between Long-and Short-lived Murien Species

Ellen Buchweitz-Milton, Ph.D.Rutgers Medical SchoolAged Brain Perfused Capillary Morphometry& O2 Consumption

Jeffrey A. Chesky, Ph.D.Sangamon State UniversityEffects of Aging upon Myocardial Adaptationto Exercise

Ursula C. Drager, M.D.Harvard Medical SchoolNeurofilament Abnormalities in DamagedNerve Cells

Andrew P. Goldberg, M.D.Johns Hopkins University School of MedicineAdiposity, Physical Fitness and MetabolicFunction during Aging

Margaret L. Heidrick, Ph.D.University of NebraskaChanges with Age in the T-lymphocytePlasma Membrane

Victoria P. Knutson, Ph.D.University of Texas Health Science Center atHoustonEffects of Aging on Insulin Receptor andGlucose Metabolism

Douglas L. Schmucker, Ph.D.University of California, San Francisco Schoolof MedicineEffects of Aging on the Liver Mixed FunctionOxidase System

R.S. Sohal, Ph.D.Southern Methodist UniversityRelationship between DNA Strand Breaksand Aging

William E. Sonntag, Ph.D.Bowman Gray School of Medicine at WakeForest UniversityRegulation of Growth Hormone and ProteinSynthesis with Age

AFAR/Glenn Breakthroughsin Gerontology (BIG) Award

Two-year awards to provide timely support to pilot research programsthat may be of relatively high risk but offer significant promise of yield-ing transforming discoveries in the fundamental biology of aging. Thisprogram, sponsored by the Glenn Foundation for Medical Research,began in 2005.

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Joseph W. Starnes, Ph.D.University of PennsylvaniaExercise and Diet on Bioenergetics in theAging Rat

Linda Taylor, Ph.D.Boston University Medical CenterChanges in Endothelial Cell ProstacyclinSynthesis with Age

Marilyn L. Thoman, Ph.D.Scripps Clinic, San DiegoRestoration of Immune Function in the Agedwith Lymphokines

George C. Webster, Ph.D.Florida Institute of TechnologyControl of Gene Expression as a Factor inSenescence

1983 GranteesCynthia M. Beall, Ph.D.Case Western Reserve UniversityLifelong High Physical Activity Level and theAging Process

W. Ted Brown, M.D., Ph.D.New York State Institute for Basic ResearchBiochemical Studies of Werner Syndrome asa Model of Aging

Arthur Cherkin, Ph.D.David Geffen School of Medicine at theUniversity of California, Los AngelesSenile Dementia: Combination Drug Therapyand Toxicity

Fulton T. Crews, Ph.D.University of Florida School of MedicineInteraction of Acetylcholine, PeptideNeurotransmitters and Membrane Propertiesduring Aging

John Ellis, Ph.D.University of VermontCentral and Peripheral MuscarinicCholinergic Receptors

William B. Ershler, M.D.University of VermontThymic Transplantation of Immunescence

Caleb E. Finch, Ph.D.University of Southern CaliforniaAging and Monoamine Receptors in theHuman Brain

Phillip K. Fulkerson, M.D.Ohio State UniversityCrystal Analysis of Mineral Deposits inSenile Aortic Stenosis

Paula B. Goldberg, Ph.D.Medical College of PennsylvaniaPsychotropp/Antiarrythmic DrugInteractions in Aging

Michael Klagsbrun, Ph.D.Children’s Hospital, BostonRole of Cartilage-derived Growth Factor inOsteoarthritis

Linda J. Kraus, Ph.D.Boston University School of MedicineImmune and Neuroendocrine RegulatoryInteractions in Alzheimer’s Disease and Aging

Robert J. Luchi, M.D.Baylor College of MedicineLeft Ventricular Function in Patients 70 Years or Older

Kenneth L. Minaker, M.D.Harvard Medical SchoolMechanism of Age-related Loss of LeanBody Mass

John T. Pinto, Ph.D.Sloan-Kettering InstitutePsychoactive Drugs and Vitamin B2Metabolism in Aging

Marcus M. Reidenberg, M.D.Cornell University Medical CollegePolyamine Accumulation in the Elderly

Douglas L. Schmucker, Ph.DUniversity of California, San Francisco Schoolof MedicineEffects of Aging on Hepatobilliary Functions

David Soifer, Ph.D.New York Institute for Basic Research inDevelopmental DisabilitiesMonoclonal Antibodies for the Study ofAlzheimer’s Disease

Robert E. Till, Ph.D.University of North DakotaEffects of Vasopressin on Age Differences inMemory

Richard F. Walker, Ph.D.University of Kentucky College of MedicineA Pacemaker for Aging in the FemaleReproductive System

Diana S. Woodruff-Pak, Ph.D.Stanford UniversityBrain Correlates of Memory in Old Age

1982 GranteesEdward D. Bird, M.D.Harvard Medical SchoolMonoamines in CSF and Postmortem Brainin Alzheimer’s Disease

Dennis E. Buetow, Ph.D.University of IllinoisQ-tRNAs and Aging

Joseph T. Coyle, M.D.Johns Hopkins University School of MedicineCortical Cholinergic Lesion: Model forAlzheimer’s Disease

John M. Lowenstein, Ph.D.Brandeis UniversityMolecular Species of MembranePhospholipids in the Aging Rat

Peter V. Rabins, M.D.Johns Hopkins University School of MedicineThe Dementia of Depression: CAT ScanCorrelates

2005 RecipientsKatrin Andreasson, M.D.Johns Hopkins University School of MedicineFunction of the PGE2EP Receptors in theDevelopment of Alzheimer’s Disease

Steven Artandi, M.D., Ph.D.Stanford UniversityActivation of Epidermal Stem Cells byTelomerase

Anne Brunet, Ph.D.Stanford UniversityRole of FOXO Transcription Factors inMammalian Longevity

Fen-Biao Gao, Ph.D.J. David Gladstone Institutes at the Universityof California, San FranciscoIdentification of Genetic Pathways ThatReduce aß Toxicity on Neuronal Structures

Adam Antebi, Ph.D.Baylor College of MedicinePurification of a lipophilic hormone regulat-ing C. elegans diapause and aging

Scott D. Pletcher, Ph.D.Baylor College of MedicineGenetic mechanisms of enhanced immunefunction and delayed functional senescencein Drosophila melanogaster

AFAR/Pfizer Innovations in Aging Research Award

Two-year awards for promising junior faculty scientists who wish to starthighly innovative projects focused on the basic biology of aging and itsrelationship to human disease. Sponsored by Pfizer Inc. This program wasactive from 2004 to 2005.

AFAR Affiliate Research Grant Program

2005 GranteesAFAR-OhioErik D. Andrulis, Ph.D.Case Western Reserve UniversityMechanisms of mRNA Turnover duringAging

AFAR-SoutheastPaul Holzheimer, M.D.Emory UniversityInvestigating the Structural and FunctionalNeuroanatomy of Late-life Depression

Anna Moore, Ph.D.Emory UniversitySubcortical Function: Contributions toHemispheric Asymmetry Reduction in OlderAdults

Dan Sorescu, M.D.Emory UniversityThe Role of Nox4 in Cardiac Senescence

AFAR-Upstate New YorkVera Gorbunova, Ph.D.University of RochesterChanges in the Levels of DNA Double-strand Break Repair Proteins during Agingand Cellular Senescence

2004 GranteesAFAR-SoutheastLing Li, D.V.M., Ph.D.University of Alabama at BirminghamStatins for Enhancing Learning and Memoryin Normal Aging

AFAR-Upstate New YorkHeinrich Jasper, Ph.D.University of Rochester Medical CenterRegulatory Interactions between JNK andInsulin Signaling in the Control of Lifespan

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Adam Gazzaley, M.D., Ph.D.University of California, BerkeleyCognitive Aging: Elucidating the RelationshipBetween Structure Function and Behavior

Michael S. Grotewiel, Ph.D.Virginia Commonwealth UniversityGenetic Dissection of Functional Senescencein Drosophila

Jiyan Ma, Ph.D.Ohio State University Research FoundationThe Role of Ubiquitinated Prion Protein inNeurodegeneration

David K. Simon, M.D., Ph.D.Harvard Medical SchoolMitochondrial DNA Repair and Parkinson’sDisease

Zhiming Suo, M.D.Midwest Biomedical Research FoundationG protein Coupled Receptor Kinase-5Deficiency, Muscarinic NeurotransmissionDysfunction and NeurofibrillaryDegeneration In vitro

2004 RecipientsZheng-yi Chen, Ph.D.Massachusetts General HospitalHair Cell Regeneration Through Cell Division

Jay M. Edelberg, M.D., Ph.D.Weill Medical College of Cornell UniversityCardiac Myocyte Derivation from AgingBone Marrow Cells

Biao Zheng, M.D., Ph.D.Baylor College of MedicineOvercoming Age-associated ImmuneDeficiency by Immune Complex Vaccination

2000 Age-relatedNeurodegenerativeDiseasesAzad Bonni, M.D., Ph.D.Harvard Medical SchoolNeurotrophin Regulation of Amyloid ß-inducedNeuronal Degeneration and Cell Death

Frank M. LaFerla, Ph.D.University of California, IrvineMolecular Determinants of Presenilins inIntracellular Calcium Signaling Pathways

James Lah, M.D., Ph.D.Emory UniversityNormal and Abnormal Function ofPresenilin-1 in Endosomes

Glenn C. Telling, Ph.D.University of Kentucky Medical CenterIn Vitro Studies of Human Prions

1999 CardiovascularDiseases and Aging Vincent L. Cryns, M.D.Northwestern University Medical SchoolRole of Mitochondrial Injury in IschemicMyocardial Cell Death and Myocardial Aging

Jay M. Edelberg, M.D., Ph.D.Weill Medical College of Cornell UniversityMolecular Enhancement of SenescentCardiac Chronotropy

Roger J. Hajjar, M.D.Harvard Medical SchoolRestoration of Diastolic Function in theSenescent Heart by Gene Transfer

Domenico Pratico, M.D.University of PennsylvaniaIn Vivo Isoform-specific Effects ofApolipoprotein E on AdvancedAtherosclerosis

2003 Metabolic Controland Late Life DiseasesYih-Woei C. Fridell, Ph.D.University of Connecticut Health CenterMitochondrial Uncoupling and Aging

Mary J. Kelley, Ph.D.Oregon Health and Science UniversityIntegrin Sensing in Late-onset Glaucoma

Kevin R. Short, Ph.D.Mayo Clinic, RochesterAge Effects on Mitochondria: From Gene toFunction in Different Tissues

Hong Yang, M.D.Meharry Medical CollegeAge-related Increase in the Sensitivity ofEndothelial Cells to Oxidized Lipids: TheRole of Reactive Oxygen Species

2002 Immunologyand AgingChristopher B. Forsyth, Ph.D.Rush-Presbyterian-St. Luke’s Medical CenterEffect of Aging on Integrin Regulation ofMMP-13 in Human Chondrocytes

Lap Ho, Ph.D.Mount Sinai School of MedicineCharacterizing the Influence of ImmuneInflammatory Activities in the ClinicalProgression of Alzheimer’s DiseaseDementia

Laura Anne Vogel, Ph.D.Illinois State UniversityGeneration of Memory Responses by Agedß-lymphocytes

2001 Hormonesand AgingAnne R. Cappola, M.D.University of MarylandAndrogens, Myostatin, and Sarcopenia inOlder Women

Naibedya Chattopadhyay, Ph.D.Brigham & Women’s HospitalAnabolic Actions of Ca2+-sensing Receptorin Osteoblastic Cells

Karyn M. Frick, Ph.D.Yale UniversityEstrogen Replacement in Middle-agedFemale Mice: Implications for the Treatmentof Menopausal Women

Joseph M. Zmuda, Ph.D.University of PittsburghMolecular Epidemiology of Sex SteroidMetabolism Genes and Bone Mass in Afro-Caribbean Men

Paul Beeson Career DevelopmentAwards in Aging Research Program

(formerly the Paul Beeson Physician Faculty Scholars in Aging Research Program)

Three-to five-year awards to sustain and promote the research careers ofclinically trained individuals who are pursuing research careers in aging.The program is a collaboration between AFAR, the National Institute onAging (NIA), The John A. Hartford Foundation, The Atlantic Philanthropies,The Starr Foundation, the NIH Office of Dietary Supplements and theAlliance for Aging Research. The Commonwealth Fund was a previouspartner in this program.

2005 ScholarsLiana G. Apostolova, M.D.University of California, Los AngelesStructural MRI Outcome Predictors in MCI

Malaz A. Boustani, M.D., M.P.H.Indiana University School of MedicineEnhancing Care for Hospitalized Older Adultswith CI

Jennifer S. Brach, Ph.D.University of PittsburghGait Variability: Epidemiology, Assessment &Management

Arleen F. Brown, M.D., Ph.D.University of California, Los AngelesNeighborhoods and the Management ofChronic Conditions

Cynthia M. Carlsson, M.D.University of Wisconsin Medicine SchoolEffect of Statins on Pathobiology ofAlzheimer’s Disease

Daniel R. Goldstein, M.D.Yale UniversityStrategies to Enhance Immunity in Aging

Wendolyn S. Gozansky, M.D., M.P.H.University of Colorado Health Sciences Centerat DenverCortisol Metabolism & Central AdiposityAfter Menopause

Leanne Groban, M.D.Wake Forest University School of MedicineGrowth, Angiotensin II, and Cardiac Aging

Arti Hurria, M.D.Memorial Sloan-Kettering Cancer CenterCan Geriatric Assessment Predict OncologyOutcomes?

Pearl H. Seo, M.D., M.P.H.Duke University Medical CenterPPARgamma: Biomarker for Breast Cancerin Older Women

Dellara F. Terry, M.D., M.P.H.Boston University School of MedicineCentenarian Offspring and Vascular DiseaseResistance

2004 ScholarsSandy Chang, M.D., Ph.D.M.D. Anderson Cancer Center at the Universityof TexasTelomere-induced Genomic Instability inPremature Aging

AFAR/Pfizer Research GrantOne- to two-year award provided support for junior faculty (M.D.’s andPh.D.’s) who demonstrated a commitment to the field of aging andaddressed specific areas of research that relate to the care of an aging population. Sponsored by Pfizer Inc. This program was active from 1999 to 2003.

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Cathleen S. Colon-Emeric, M.D.Duke University Medical CenterEvidence-based Medicine in the SkilledNursing Facility

William Dale, M.D., Ph.D.University of ChicagoEmotions in Medical Decision-making inOlder Adults

Lee E. Goldstein, M.D., Ph.D.Brigham and Women’s Hospital/HarvardMedical SchoolAlzheimer’s Disease Beta-amyloid in theLens

Cary P. Gross, M.D.Yale UniversityThe Impact of Comorbidity on Older CancerPatients

John J. Lehman, M.D.Washington UniversityMitochondrial Control by PGC-1a in Youngand Aging Heart

Andrew P. Lieberman, M.D., Ph.D.University of MichiganModifiers of Polyglutamine Toxicity

Atul Malhotra, M.D., Ph.D.Brigham Women’s Hospital/Harvard MedicalSchoolAging Influence on the Development ofSleep Apnea

Marcin Sadowski, M.D., Ph.D.New York University School of MedicineBlocking APOE/aß Binding as a Novel ADTherapy

Catherine A. Sarkisian, M.D., M.S.P.H.University of California, Los Angeles School ofMedicineIntervention to Raise Octogenarians’Walking Levels

Clemens R. Scherzer, M.D.Brigham & Women’s Hospital/Harvard MedicalSchoolGenomic and Genetic Analysis ofParkinson’s Disease

Lisa C. Silbert, M.D.Oregon Health and Science UniversityWhite Matter Change and CNS Process inthe Elderly

Joe Verghese, M.D.Albert Einstein College of MedicineLatent Mobility Abnormalities and Disability

2003 ScholarsMeredith Hawkins, M.D.Albert Einstein College of MedicineThe Role of Nutrient Excess in Mediating theInsulin Resistance of Aging

Michael C. Irizarry, M.D.Massachusetts General Hospital -East/Harvard Medical SchoolBeta-secretase and Alzheimer’s Risk withAging

Robert A. Marciniak, M.D., Ph.D.University of Texas Health Science Center atSan AntonioOxidative Stress and Telomere Maintenance:In Vitro and In Vivo Studies

Laura E. Niklason, M.D., Ph.D.Duke University School of MedicineLifespan Extension of Vascular Cells forTissue Engineering

Michael A. Schwarzschild, M.D., Ph.D.Harvard Medical SchoolSorting Out Clues to Parkinson’s Disease:Caffeine, Postmenopausal Estrogen andAddiction

Jurgen Ünützer, M.D., M.P.H.University of California, Los AngelesNeuropsychiatric InstituteImproving Care for Chronic Pain and LateLife Depression

2001 ScholarsAsa Abeliovich, M.D., Ph.D.Columbia University College of Physicians &SurgeonsMolecular Analysis of the Familial ParkinsonDisease Genes Parkin and Alpha-synuclein

Katrin Andreasson, M.D.Johns Hopkins University School of MedicineMechanisms of Cyclooxygenase-2-depend-ent Neuronal Injury in Aging andNeurodegenerative Disease

Eric A. Coleman, M.D., M.P.H.University of Colorado Health Sciences CenterReducing Care Fragmentation Across Sitesof Geriatric Care

Jay M. Edelberg, M.D., Ph.D.Weill Medical College of Cornell UniversityRestoration of Senescent CardiacAngiogenic Activity by Bone MarrowTransplantation

Wesley Ely, M.D., M.P.H., F.C.C.P.Vanderbilt University School of MedicineThe Role of Delirium and Psychoactive DrugUse on Outcomes Following MechanicalVentilation in Older Persons

Roger J. Hajjar, M.D.Harvard Medical SchoolTargeting Signaling Pathways in AgingHearts by Gene Transfer

James A. Mastrianni, M.D., Ph.D.University of Chicago School of MedicineAging and the Misfolded Protein: PrionDisease as a Model for Disaggregating theAggregate

Michael C. Naski, M.D., Ph.D.University of Texas Health Science Center atSan AntonioMatrix Homeostasis and Gene Expression inAging Cartilage

M. Carrington Reid, Ph.D., M.D.Yale University School of MedicineDetermining the Impact of Back Pain onPhysical and Social Disability Among OlderAdults

Mary Whooley, M.D.University of California School of Medicine,San FranciscoMechanisms of Association BetweenDepression and Poor Health Outcomes inOlder Patients

Kristine Yaffe, M.D.University of California School of Medicine,San FranciscoDeterminants of Cognitive Change and itsOutcomes in African-American and WhiteElders

2000 ScholarsBrock Beamer, M.D.Johns Hopkins University School of MedicineGenetic Variation in PPAR-y and RXRd:Effects on Body Composition andMetabolism in Older Adults

Gunnar K. Gouras, M.D.Weill Medical College of Cornell UniversityNeuronal A-beta Accumulation: Aging andOxidative Stress

Mary Beth Hamel, M.D., M.P.H.Harvard Medical SchoolDecision-making and Outcomes for ElderlyPatients with Surgical Problems

Joshua M. Hare, M.D.John Hopkins University School of MedicineThe Role of Nitric Oxide in Aging-relatedCardiovascular Adaptions

Fuki M. Hisama, M.D.Yale School of MedicineThe Molecular Basis of Aging in WernerSyndrome

Jason H. Karlawish, M.D.University of Pennsylvania School of MedicineCaregiver and Patient Preferences for theTreatment of Alzheimer’s Disease

Jean S. Kutner, M.D., M.S.P.H.University of Colorado Health Sciences CenterSymptom Management at the End of Life:Decreasing Distress and Improving Qualityof Life

Brett Lauring, M.D., Ph.D.Columbia University College of Physicians &SurgeonsAn In Vitro Assay for Gamma SecretaseProcessing of the Amyloid Precursor Protein

Frank S. Lee, M.D., Ph.D.University of Pennsylvania School of MedicineProtein Kinases and Alzheimer’s Disease

R. Sean Morrison, M.D.Mount Sinai School of MedicineInterventions to Improve Pain Outcomes

Scott A. Small, M.D.Columbia University College of Physicians &SurgeonsFunctional Imaging of the HippocampalFormation in Age-related Memory Decline

Kenneth Langa, M.D., Ph.D.University of MichiganLong-term Outcomes of Caring for aDisabled Spouse

Sarah H. Lisanby, M.D.Columbia University College of Physicians andSurgeonsBrain Stimulation and PharmacologicalStrategies to Reduce the Cognitive SideEffects of ECT in Geriatric Depression

Jack M. Parent, M.D.University of MichiganStimulation of Endogenous Neural StemCells to Promote Recovery after Stroke

Henry L. Paulson, M.D., Ph.D.University of IowaRNA interference (RNAi) as Novel Therapyfor Age-related Disease

Elizabeth A. Phelan, M.D.University of WashingtonImproving Primary Care of Older Adults

Wendy S. Post, M.D.Johns Hopkins University School of MedicineVascular Properties and Genetics Associatedwith Longevity in the Amish

Norman Sharpless, M.D.University of North Carolina at Chapel HillThe Role of the Tumor Suppressor P16ink4a in Mammalian Aging

Michael G. Shlipak, M.D., M.P.H.University of California, San FranciscoPreventing Heart Failure in Elderly Personswith Chronic Renal Insufficiency

Reisa A. Sperling, M.D., M.M.Sc.Brigham & Women’s Hospital/Harvard MedicalSchoolInvestigating the Neural Underpinnings ofMemory Impairment in Aging and EarlyAlzheimer’s Disease

2002 ScholarsDavid J. Casarett, M.D.University of Pennsylvania School of MedicineImproving Decision-making about End-of-life Care and Promoting Earlier Referral toHospice

James E. Galvin, M.D.Washington University School of MedicineIn Vitro and In Vivo Models ofSynucleinopathies

Brad Johnson, M.D., Ph.D.University of Pennsylvania School of MedicineFunctions of the Werner Syndrome Familyof Proteins in Telomerase-deficient Mice andYeast

Albert R. La Spada, M.D., Ph.D.University of Washington School of MedicineDevelopment of Therapies for PolyglutamineNeurodegeneration and Related Disorders

Michael T. Lin, M.D.Weill Medical College of Cornell UniversityMitochondrial DNA Mutations in Aging andAlzheimer’s Disease

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1999 ScholarsKenneth E. Covinsky, M.D., M.P.H.University of California, San FranciscoOutcomes of Frail Nursing Home-eligibleElders Living in the Community

Matthew P. Frosch, M.D., Ph.D.Harvard Medical SchoolEstrogen, Aging and Alzheimer’s DiseaseMechanisms and Model Systems

Daniel T. Laskowitz, M.D.Duke University Medical CenterApolipoprotein E, Microglial Activation, andNeurodegenerative Disease

Dale Leitman, M.D., Ph.D.University of California, San FranciscoRole of Coactivators in Estrogen Repressionof Gene Transcription

Richard Z. Lin, M.D.University of Texas Health Science Center atSan AntonioThe Role of Oxidative Stress in Aging Effectson Vascular Smooth Muscle Cell Growthand Signal Transduction

David R. Lynch, M.D., Ph.D.University of PennsylvaniaExcitotoxicity in NeurodegenerativeDisorders: New Understanding from NMDAReceptor Subtypes

Edward R. Marcantonio, M.D., S.M.Harvard Medical SchoolReducing Delirium in Post-acute Care: An Interventional Trial

Mitchell S. Nobler, M.D.Columbia University College of Physicians &SurgeonsSerotonin and PET Neuroimaging in NormalAging and Geriatric Depression.

Anne Louise Oaklander, M.D., Ph.D.Harvard Medical SchoolCellular Mechanisms of Chronic NeuropathicPain

Thomas A. Rando, M.D., Ph.D.Stanford University School of MedicineMechanisms of Age-related Muscle Atrophy:The Role of Cellular Antioxidant Defenses

1998 ScholarsHelene Benveniste, M.D., Ph.D.Duke University Medical CenterIn Vivo Magnetic Resonance Microscopyand Alzheimer’s Disease: Defining andStaging the Progression of Alzheimer’sPathology in Transgenic MiceOverexpressing Beta Amyloid Protein

Laura L. Dugan, M.D.Washington University School of MedicineMechanisms of Neuroprotection by C60Derivatives: Relevance to Oxidative StressDuring Aging

Terri R. Fried, M.D.Yale University School of MedicineA Longitudinal Study of Terminally IllPatient’s Preference for Care

Anne M. Kenny, M.D.University of Connecticut Health CenterMechanisms of Bone Loss in Older Menwith Low Testosterone Levels

Alison A. Moore, M.D., M.P.H.University of California, Los Angeles School ofMedicineScreening for Harmful and HazardousDrinking in Older Persons

Thomas T. Perls, M.D., M.P.H.Harvard Medical SchoolThe Genetics of Longevity

Eric D. Peterson, M.D., M.P.H.Duke University Medical CenterToward a Rational Use of Revascularizationin the Aged

Scott Turner, M.D., Ph.D.University of Michigan Medical SchoolThe Role of X11& in Amyloid PrecursorProtein

Jeremy D. Walston, M.D.Johns Hopkins University School of MedicineMolecular Etiologies of Age-related Changesin Body Composition

Raymond Yung, M.D.University of Michigan Medical SchoolLymphocyte Homing in Aging

1997 ScholarsNir Barzilai, M.D.Albert Einstein College of MedicineThe Effect of Age-dependent Increase inVisceral Fat on Insulin Action and Secretion

Michele Bellantoni, M.D.Johns Hopkins University School of MedicineGrowth Hormone and Sex Steroid Effects onBone in Older Women

James R. Burke, M.D., Ph.D.Duke University Medical CenterPolyglutamine Proteins as a Model Systemfor Studying Protein Aggregation and CellDeath in Aging and NeurodegenerativeDisease

Mark D’Esposito, M.D.University of Pennsylvania School of MedicineFunctional Neuroimaging Studies ofWorking Memory in Normal Human Aging

Thomas M. Gill, M.D.Yale University School of MedicineIdentifying the Events that PrecipitateFunctional Dependence Among Community-living Elderly Persons

Bernard F. Godley, M.D., Ph.D.University of Texas Medical BranchThe Role of Oxidative Damage and Repair inAge-related Macular Degeneration

Todd E. Golde, M.D., Ph.D.Mayo Clinic Medical School, JacksonvilleProteolytic Generation of the Amyloid BetaPeptide in Alzheimer’s Disease

Helen Hoenig, M.D., M.P.H.Duke University Medical CenterAn Investigation of the Physical Costs andthe Quality of Life Benefits of Wheelchairsfor Older Persons

Elan D. Louis, M.D., M.S.Columbia University College of Physicians andSurgeonsFunctional Correlates of Essential Tremor

Charles A. Thornton, M.D.University of Rochester School of Medicine andDentistryPathophysiology of Myotonic Dystrophy, aProgeroid Syndrome

1996 ScholarsChristopher M. Callahan, M.D.Indiana University School of MedicineThe Use of Percutaneous EndoscopicGastrostomy Among Older Adults in aCommunity Setting

Robert W. Doms, M.D., Ph.D.University of Pennsylvania School of MedicinePresinilin 1, APP, and Alzheimer’s Disease

Murali Doraiswamy, M.D.Duke University Medical CenterApolipoprotein E Type 4 Allele and CerebralMetabolism in Relatives at Risk for FamilialAlzheimer’s Disease

Harlan M. Krumholz, M.D.Yale University School of MedicineClinical Spectrum, Treatment and Outcomeof Elderly Congestive Heart Failure Patients

Makau Lee, M.D., Ph.D.University of Mississippi Medical CenterStudies on Aging, Dietary Restriction andGastric Mucosal Defense

Richard F. Loeser, M.D.Rush Medical CollegeGrowth Factors and Aging in Cartilage

Karen M. Prestwood, M.D.University of Connecticut Health CenterBone Turnover and the Response toEstrogen in Older Caucasian, Hispanic andAfrican-American Postmenopausal Women

May J. Reed, M.D.University of Washington School of MedicineAngio-genesis, the Extra-cellular Matrix, andWound Repair in Aging

Robert Glenn Smith, M.D., Ph.D.Baylor College of MedicineRole of Voltage-gated Calcium Channel AutoAntibodies in Motoneuron Injury in ALS

1995 ScholarsAshley I. Bush, M.D., D.P.M., Ph.D.Harvard Medical SchoolZinc Exposure as a Risk Factor forAlzheimer’s Disease

Ted M. Dawson, M.D., Ph.D.Johns Hopkins University School of MedicineGene Therapy for Neurologic Disorders

David M. Holtzman, M.D.Washington University School of MedicineMolecular and Cellular Factors that Play aRole in Maintaining Neuronal Form andFunction in the Normal Aging CNS and HowThey May Be Altered in AD

Edward H. Koo, M.D.University of California, San Diego School ofMedicineThe Mechanism of Amyloid ß-protein (aß)Production from the Amyloid PrecursorProtein (APP) in Neurons

Mark S. Lachs, M.D., M.P.H.Weill Medicine College of Cornell UniversityThe Morbidity and Mortality of Elder Abuse

Frank M. Longo, M.D., Ph.D.University of California, San Francisco Schoolof MedicineNew Strategies for TreatingNeurodegenerative Disease

Richard A. Marottoli, M.D., M.P.H.Yale University School of MedicineDevelopment of a Strategy for IdentifyingWhich Older Drivers are at Risk for Crashesand Moving Violations

Lina M. Obeid, M.D.Medical University of South CarolinaRole of Ceramide in Inducing the SenescentPhenotype through Activating a GrowthSuppressor Pathway and by Inhibiting aMitogenic Pathway

Peter Reaven, M.D.University of California, San Diego School ofMedicineThe Relationship of Aging and AntioxidantDefense Systems to Atherosclerosis

Alan R. Shuldiner, M.D.University of Maryland School of MedicineGenetics of Diabetes and Obesity in theElderly

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2005 InvestigatorsMuralindhar Beeram, M.D.University of Texas Health Science Center atSan Antonio

Steven M. Handler, M.D.University of Pittsburgh School of Medicine

2004InvestigatorsOumitana Kajkenova, M.D.University of Arkansas for Medical Sciences

Josh F. Peterson, M.D., M.P.H.Vanderbilt University

2003InvestigatorsJoseph V. Agostini, M.D.Yale University School of Medicine

Robert G. Riekse, M.D.Seattle Institute for Biomedical & ClinicalResearch

2002InvestigatorsCynthia M. Carlsson, M.D.Madison Veterans Affairs Geriatric Research,Education and Clinical Center (GRECC)

Margaret Pisani, M.D.Yale University School of Medicine

2001InvestigatorsArti Hurria, M.D.Memorial Sloan Kettering Cancer Center

Cathy C. Lee, M.D.University of Michigan Health Systems

2000InvestigatorsHelen K. Edelberg, M.D.Mount Sinai School of Medicine

Wesley Ely, M.D., M.P.H., F.C.C.P.Vanderbilt University School of Medicine

1999InvestigatorsJames B. Wendt, M.D.University of Illinois at Chicago

1998InvestigatorsEdward S. Connolly, Jr., M.D.Columbia University College of Physicians &Surgeons

Richard Lin, M.D.University of Texas Health Science Center atSan Antonio

1997InvestigatorsHoang Duong, M.D.Columbia University College of Physicians &Surgeons

Tina V. Hartert, M.D.Vanderbilt University Medical Center

1996InvestigatorsRebecca J. Beyth, M.D.Case Western Reserve University School ofMedicine

Daniel T. Kaufer, M.D.University of Pittsburgh School of Medicine

1995InvestigatorsBarbara Clark, M.D.Harvard Medical School

Rahmawati Sih, M.D.Saint Louis University School of Medicine

1994InvestigatorsAdalsteinn Gudmundsson, M.D.University of Wisconsin

Fouzia Lagrhissi-Thode, M.D.University of Pittsburgh School of Medicine

1990InvestigatorsDeborah N. Goldner-Robin, M.D.Vanderbilt University School of Medicine

Eugenie L. Siegler, M.D.University of Pennsylvania School of Medicine

1989InvestigatorsMeghan B. Gerety, M.D.University of Texas Health Science Center atSan Antonio

Margaret Winker, M.D.University of Chicago Medical Center

1988InvestigatorsGary A. Ford, M.D., M.R.C.P.Stanford University Medical Center

Jerry H. Gurwitz, M.D.Harvard Medical School

Stephen C. Montamat, M.D.University of Washington School of Medicine

Bruce G. Pollock, M.D., Ph.D.University of Pittsburgh School of Medicine

AFAR/Ellison Medical Foundation SeniorPostdoctoral Fellows Research Program

Two-year fellowships to encourage and further the careers of postdoctoralfellows (both M.D.’s and Ph.D.’s) with at least 3 and not more than 5 yearsof postdoctoral training, in the fundamental mechanisms of aging.

1993InvestigatorsNabil Andrawis, M.D., Ph.D.Brown University School of Medicine

Susan Kalish, M.D.Harvard Medical School

1992InvestigatorsDean L. Kellogg, Jr., M.D., Ph.D.University of Texas Health Science Center atSan Antonio

Fred Kusumoto, M.D.University of California, San Francisco

1991InvestigatorsKayla I. Brodkin, M.D.University of Washington School of Medicine

Mark Monane, M.D., M.S.Harvard Medical School

2005 FellowsJohannes H. Bauer, Ph.D.Brown UniversityMechanism(s) of p53-dependent LifespanExtension

Malene Hansen, Ph.D.University of California, San FranciscoMolecular Mechanisms of LifespanRegulation by the Insulin/IGF-1 Pathways inC. elegans

Supriya Srinivasan, Ph.D.University of California, San FranciscoThe Role of Serotonergic Signaling inEnergy Homeostasis During Aging

2004 FellowsShermali Gunawardena, Ph.D.University of California, San DiegoAxonal Transport and NeurodegenerativeDisease: Is Perturbation in VesicularTransport an Early Neuronal DysfunctionPathway?

Jeong Hyeon Park, Ph.D.The Rockefeller UniversityThe Roles of p53-interacting ChromatinModifying Complexes in Human CellularAging

Sarah Sagi, Ph.D.University of California, San DiegoNSAID Modulation of g- and ß-secretase

2003 FellowsHaim Cohen, Ph.D.Harvard Medical SchoolDNA Break Repair Controlled by SIRT1 viathe Deacetylation of Ku70 and Ku80

Coleen T. Murphy, Ph.D.University of California, San FranciscoDiscovery and Analysis of C. elegansLifespan Genes

Marc F. Poitras, Ph.D.New York University School of MedicineMolecular Mechanisms of Tankurase1-induced Telomere Elongation

AFAR/Merck Junior Investigator Award inGeriatric Clinical Pharmacology

Two-year awards addressed the critical need of developing more physicianswith a command of geriatric clinical pharmacology. Sponsored by theMerck Company Foundation. This program was active from 1988 to 2005.

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AFAR/Glenn Research Grant forPostdoctoral Fellows

One-year fellowships to encourage and further the careers of postdoc-toral fellows (both M.D.’s and Ph.D.’s) with at least 2 and not more than5 years of postdoctoral training, in the fundamental mechanisms ofaging. Sponsored by the Glenn Foundation for Medical Research. Thisprogram was active from 2001 to 2004.

2004 FellowsPaul D. Allen, Ph.D.University of RochesterAging-related Neural Desynchronization inthe Auditory Brainstem

Johannes H. Bauer, Ph.D.University of Connecticut Health CenterThe Role of p53 in Lifespan Extension

Robert Dekroon, Ph.D.Duke University Medical CenterThe Role of Intracellular Pathways Mediatedby Lipoproteins in the Regulation ofApoptosis

Rugang Zhang, Ph.D.Fox Chase Cancer CenterMolecular Basis of Cellular Senescence

2003 FellowsArjumand Ghazi, Ph.D.University of California, San FranciscoRole of the Somatic Gonad in the Regulationof Caenorhabditis elegans Aging

David W. Killilea, Ph.D.Children’s Hospital Oakland Research InstituteCellular Aging Alters Intracellular IronHomeostasis

Gawain McColl, Ph.D.Buck Institute for Age ResearchThe Role of KU70 in Stress Resistance andAging

Andrej Podlutsky, Ph.D.University of Texas Health Science Center atSan AntonioStress Tolerance and Bat Aging

2002 FellowsAdam H. Gazzaley, M.D., Ph.D.University of California, BerkeleyNeural Mechanisms of Memory Function inNormal Aging

Dejan Milatovic, Ph.D.Vanderbilt UniversityCerebral Oxidative Damage in the Models ofAdvanced Age, Inflammation andExcitotoxicity

Anne Simon, Ph.D.California Institute of TechnologyStudy of Long-lived Mutants of theEcdysone Receptor

Meng-Ping Tu, Ph.D.Brown UniversityYeast-restriction in Juvenile State ExtendsAdult Lifespan in Drosophila melanogaster

2001 FellowsDebdutta Bandyopadhay, Ph.D.Baylor College of MedicineRole of Histone Deacetylation inMelanocytes Senescence

Kathy Barsz, Ph.D.University of Rochester Medical CenterThe Effect of Aging on PhysiologicalCorrelates of Masked Intensity Judgments

Nilufer Ertekin-Taner, M.D.Mayo Clinic, JacksonvilleIdentification of the Novel Late-onsetAlzheimer’s Disease Gene on Chromosome10 Using Plasma Amyloid Beta Levels as aSurrogate Genetic Marker

Faith Gunning-Dixon, Ph.D.Hospital of the University of PennsylvaniaThe Neural Basis of Age-related Declines inEpisodic Memory

Kimmo J. Hatanpaa, M.D., Ph.D.Johns Hopkins UniversityCatabolism of Alzheimer Amyloid Beta-protein

Shunai Jiang, M.D., Ph.D.Emory UniversityFas Ligand and Fas in Aging

Pankaj Kapahi, Ph.D.California Institute of TechnologyIsolation and Characterization of Genes ThatExtend Lifespan and PreventNeurodegeneration Using Drosophilamelanogaster as a Model System

Plamen D. Penev, M.D., Ph.D.University of ChicagoPoor Sleep Quality and Testosterone Declinein Older Men

Claus U. Pietrzik, Ph.D.University of California, San DiegoRole of the LRP in Cytoplasmic Domain inAPP Processing

Leanne Rae Stewart, Ph.D.Washington University School of MedicineThe Involvement of Mutant PrPAccumulation and Apoptosis inNeurodegeneration in Tg(PG14) Mice

AFAR/Merck

AFAR/Merck Research Scholarships inGeriatric Pharmacology for Medical andPharmacy Students

Two- to three-month awards provided M.D. and Ph.D. students the opportunity to undertake a research project in geriatric pharmacology.Sponsored by the Merck Company Foundation. This program was activefrom 1998 to 2004.

2004 ScholarsMary Jo HessertUniversity of New EnglandAssessing Medication Compliance forElderly Patients in a New York Rural FamilyPractice

Patricia A. McHazlettTexas Tech University Health Sciences CenterDivalent Ion Channels as Drug Targets inAlzheimer’s Disease

Sarah E. SmithUniversity of California, IrvineMedication Use in Dementia Patients inAdult Day Health Centers

2003 ScholarsKelly GauthierVirginia Commonwealth UniversityCognitive, Functional and BehavioralOutcomes of Reducing Anticholinergic DrugUse in Alzheimer’s Disease Patients TakingCholinesterase Inhibitors

Courtney HoeltingTexas Tech University Health Sciences CenterCharacterization of the Agnostic andAntagonistic Effects of Selective EstrogenReceptor Modulators (SERMs) andEstrogen-related Compounds in SeptalCholinergic Neurons

Olga KaufmanUniversity of Southern CaliforniaDepression and Pain Management ofDisabled Patients Using Effective Age Model

Paul McConnellWest Virginia University School of MedicineMeasurement of Antioxidative Protection inMammalian Cells as a Means to PossiblyPrevent Neurodegenerative Aging Disorders

Angela A. McMichaelUniversity of Maryland, BaltimoreImproving Diabetes MedicationManagement in Older Adults

2002 ScholarsMark GamberUniversity of North Texas Health ScienceCenterHormone Replacement Therapy:Investigating Language Barriers

David C. JohnsonUniversity of FloridaGeriatric Chronic Pain Management: TheEffects of Including a Pain Self-assessmentin the Patient’s Medical Chart

Daniel G. KlodaUniversity of New EnglandRole of Dynorphin Peptides in Age-associat-ed Cognitive Impairment

Amanda PrestonOhio Northern UniversityThe Role of Excessive MAO-B Activity in theLearning Deficits Induced by Aging andEcstasy

Heather SturgillVirginia Commonwealth UniversityTissue Factor Polymorphism inPostmenopausal Women

Kathleen Tschantz UnroeOhio State UniversityPrescribing Medications to Older Drivers:Are Physician Resources Adequate?

2001 ScholarsAngelo A. BaccalaJohns Hopkins University School of MedicineIn Vitro RU-486 Gene Switch Regulation ofiNOS for the Treatment of ErectileDysfunction in Men Taking NitrateContaining Drugs and Those Suffering fromthe Side Effects of Viagra

Jennifer W. ChildressUniversity of Maryland, BaltimoreEvaluation of Oral Inhaler Technique Pre-and Post-interventions in Elderly Individuals

Jay ChyungHarvard Medical SchoolCharacterization of the IDE-mediatedDegradation of aß in Plasma Membranesand in Intracellular Vesicular Compartmentsof Cells

Yana DadiomovaMount Sinai School of MedicineMedication Management and Health Literacyin Community-dwelling Older Adults

Jennifer L. JohnsonUniversity of Arkansas for Medical SciencesBaseline Medication Use in DementiaPatients with Disruptive Behaviors

Reza KafiUniversity of Michigan Medical CenterTopical Vitamin A (All-trans Retinol) in theTreatment of Aged Skin

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Blake KellerCommonwealth University/Medical College ofVirginiaAge-related Differences in the Sensitivity toEthanol in Humans

Christopher MartinTexas Tech University Health Sciences CenterEffects of Phytoestrogens on the Survival ofBasal Forebrain Cholinergic Neurons In Vitro

Julia K. NguyenUniversity of California, San FranciscoIs Polypharmacy a Risk Factor for AdverseDrug Reactions in Geriatric Nursing HomeResidents?

Mai T. NguyenWestern University College of PharmacyExamining a Role for Diazepam inProtecting Nerve Cells from Death that isExposed to Alzheimer Plaque Fragments

Aimee M. WrightUniversity of FloridaThe Relationship of Cognitive-impairingMedications and Cognitive Ability in ElderlyPsychiatric Inpatients

2000 ScholarsJeffrey R. BishopUniversity of IowaNeuronal Susceptibility to EnvironmentalStressors in Parkinson’s Disease: The Roleof aß-Synuclein.

Dena DubalUniversity of KentuckyEstrogen-mediated Neuroprotection AgainstStroke Injury in Aging Female Rats:Potential Mechanisms

Yvonne C. HuckleberryWashington State UniversityAre Explicit Criteria for the Prescribing ofMedications in the Elderly Utilized? AnAssessment of Office-based Physician-patient Encounters in the United States1990-1997

Szilard KissColumbia University College of Physicians &SurgeonssRAGE Inhibition of the Post-ischemic Pro-inflammatory Axis: A Novel Treatmentfor Stroke

Sarah MiddletonBrown UniversityNitrate Use in Very Frail Elderly withCoronary Heart Disease

Melissa WellonsDuke UniversityHIV Infection: Treatments and Outcomes inOlder and Younger Patients

1999 ScholarsPatricia M. EnglePurdue UniversityPredictors of Serum AnticonvulsantConcentrations in Older Adults and RelatedTreatment Outcomes

Wei Han FangUniversity of IowaPhage Display Technique in Drug Screeningfor Alzheimer’s

David GanzHarvard Medical SchoolAnticoagulant Use and Monitoring in ElderlyPatients with Atrial Fibrillation

Kathryn L. HarrisMercer UniversityA Retrospective Study of Adverse DrugReactions Following the Administration ofthe Influenza, Pneumonia and/or Tetanus-diphtheria Vaccines to Geriatric NursingFacility Residents

Jiwon W. KimUniversity of Southern CaliforniaDrug Treatment of Managed Care Patientsand Fee-for-Service Patients of SkilledNursing Facilities - Comparison of Cost,Length of Treatment, Efficacy, and OutcomesMeasurements.

Bismruta MisraMassachusetts General HospitalClinical and Nonclinical Factors ofAntihypertensive Polypharmacy

Andrew G. SolomonVirginia Commonwealth UniversityThe Effect of Older Age on LuteinizingHormone (LH) Elimination

W. Wallace WebsterUniversity of Kansas Medical CenterAnalysis of Loosely-bound Iron inAlzheimer’s Disease Brain Tissue andCorrelation with Histopathological Changes

1998 ScholarsLanning R. BakerIdaho State UniversityMorphine Metabolites and GenderDifferences in Pain Responses in the Elderly

Irina D. BurdUniversity of Medicine and Dentistry of NewJerseyThe Importance of Neuron-AstrocyteInteractions in Adult Basal Forebrain

Jersey ChenYale University School of Medicineß-blocker Therapy for the Treatment ofAcute Myocardial Infarction in ElderlyMedicare Beneficiaries with Diabetes

James A. Edwards, Ph.D.Virginia Commonwealth UniversityAnalysis of Plasma Levels of Scopolamine inHealthy Elderly Volunteers

Kevin L. FergusonStanford UniversityThe Effects of Metformin on theDevelopment of Visceral Obesity and InsulinResistance in Fat-fed Rats

Rahul GargDuke UniversityRhoA and its Role in the Mechanism ofAction of Common Glaucoma Drugs

Cynthia O. HowellUniversity of Florida College of PharmacyThe Effect of Estrogen Deprivation on HeatShock Protein-70 Expression in Rat SkeletalMuscle

Louis J. KimColumbia UniversityActive Site-blocked Factor IXa as a NovelTreatment for Stroke in a Murine Model ofFocal Cerebral Ischemia

David D. Limbrick, M.S.Virginia Commonwealth UniversityCharacterization of Intracellular CalciumKinetics Following Glutamate Exposure in anIn vitro Model of Stroke and Aging

1997 ScholarsRoni DevlinUniversity of Colorado Health Sciences CenterComputerized Identification of PotentialAdverse Drug Events in the Elderly and theEffect on Physician Response and DrugProgram Utilization

Marc LevskyNorthwestern UniversitySSRI-induced Hyponatremia in the Elderly:Is it Real Clinical Concern?

Carol MattesUniversity of Pittsburgh Medical CenterHuman Inducible Nitric Oxide Synthase asGene Therapy for Erectile Dysfunction

Maritess MauricioStanford University School of MedicineApolipoprotein E (ApoE) Status and theEffects of Estrogen Replacement Therapy onDepression and Cognitive Function in OlderWomen

Jill ScottTufts University School of MedicineReduced Cytochrome P450-3A Activity inOld Age: An Experimental Model

Selina ShahVanderbilt University School of MedicineThe Effects of Aging on P-glycoproteinActivity in the Central Nervous System.

AFAR/Glenn Scholarships for Research in the Biology of Aging

Three-month awards provided M.D. and Ph.D. students the opportunity toconduct a research project in an area of biomedical research in aging,under the auspices of a mentor. Sponsored by the Glenn Foundation forMedical Research. This program was active from 1995 to 2004.

2004 ScholarsEzana M. AzeneJohns Hopkins UniversityGene Therapy for Peripheral NeuropathicPain

Melynda A. BarnesMount Sinai School of MedicineImmunohistochemical Analysis of SpinalCords from Disulfiram-Treated G86RSuperoxide Dismutase-1 Transgenic Mice

Ala BerdichevskyMassachusetts Institute of TechnologyIdentification of Molecular Targets of sir-2.1Gene, which Promotes Extension ofLifespan of the Nematode Caenorhabditiselegans

Eric Hau-Yun ChangNew York UniversityReceptor Dysfunction in Double Knock-inAPP+PS1 Mice

Robi GoswamiDuke UniversityRegulation of the Platelet-derived GrowthFactor Receptor-ß by G Protein-coupledReceptor Kinase-2

Jennifer A. GreenhallUniversity of California, San DiegoThe Impact of fgf1 and fgf2 on thePreservation of Cortical Neurons in theAging Mouse

Shilpa IyerUniversity of GeorgiaKlstn-M1: A Novel Yeast Model System toStudy Telomere Capping Defects andRecombinational Telomere Elongation

William W. JaCalifornia Institute of TechnologyCharacterization of Methuselah, a DrosophilaG Protein-coupled Receptor Associated withLongevity

Youngmok Charles JangUniversity of Florida, GainesvilleLong-term Caloric Restriction (CR) as aStrategy to Prevent Sarcoplasmic Reticulum(SR) Stress Induced CardiomyocytesApoptosis In Vivo

Jennifer Q. KwongWeill Medical College of Cornell UniversityModulation of Mitochondrial Homeostasisby Bcl-2 in Cells with Mitochondrial DNAMutations

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Janelle Lauer-FieldsFlorida Atlantic UniversityEngineering and Expression of ADMTS-4and ADMTS-5, Proteolytic EnzymesInvolved in Osteoarthritis Progression

Maria LehtinenHarvard UniversityCharacterization of the Role of MST1 inOxidative Stress and Aging in Caenorhabditiselegans

Jacqueline MaffucciUniversity of TexasHypothalamic Mechanisms for ReproductiveSenescence in Aging Female Rats: Roles ofNMDA Receptors and GnRH Neurons

Patrick McLaughlinUniversity of WashingtonProteomic Analysis of Proteins Related toInflammation in Parkinson’s Disease

Kathryn A. MoynihanWashington UniversityDeacetylation of the Forkhead TranscriptionFactor FOX01 by Mammalian Sir2aNegatively Regulates Insulin GeneExpression in Pancreatic ß Cells

Xuan V. NguyenUniversity of KentuckyAge-dependent Alterations in Dopamine andthe Nigrostriatal System in ProdynophinKnockout Mice

Mohammed Zeeshan OzairAga Khan UniversityAnalysis of Neural Stem Cell MigrationTowards Brain Tumors by In Vivo PhageDisplay

Annalise PaabyUniversity of PennsylvaniaSelection and Gene Regulation ofSenescence in Natural Populations ofDrosophila

Carlos J. PantojaUniversity of California, San FranciscoThe Involvement of DAF-16 and HSF-1 inthe Regulation of Small Heat Shock ProteinGenes

Julie K. PlowdenEmory UniversityEffects of Aging on the Kinetics andStrength of T-cell Antigen Presenting CellInteractions

Adolfo Sanchez-BlancoUniversity of Connecticut Health CenterUCP5 Deficiency Mimics Caloric Restrictionin Drosophila melanogaster

Kim SciarrettaUniversity of ChicagoModeling an Intermediate of Beta-amyloidFibril Formation

Kun-Chih Kelvin TsaiHarvard UniversityHeterotypic Interactions Between Stress-induced Prematurely Senescent Stroma andNeighboring Epithelial Cells in Aging andCancer

Lisa J. WhitsonUniversity of Texas Health Science Center atSan AntonioMonomerization and Amyloid Formation ofFALS-Associated Cu-Zn SuperoxideDismutase Mutants

Brice J. WilliamsMedical University of South CarolinaAltered Neurotrophin Release in Age-relatedDementia

2003 ScholarsScott B. BergerUniversity of MichiganThe Use of Glycosidases as a Means ofCorrecting Age-dependent Deficiencies of T-cell Function

Jennifer CaplaNew York UniversityInvestigating the Role of Adult VascularStem Cells in the Pathogenesis of Age-relat-ed Disease

Marci L. ChewUniversity of PittsburghSerum Anticholinergicity at SpecificMuscarinic Receptor Subtypes

Daniel J. DurandJohns Hopkins UniversityMyocardial Regeneration by Bone-marrowDerived Stem Cells in Old versus YoungWistar Rats

Andrew A. GrimmWashington UniversityThe Functional Relationship Between anNAD Biosynthesis Enzyme and the NAD-Dependent Deacetylase, SIR2, in Mammals

Mary A. HancockUniversity of UtahComparison of the Levels of OxidativeDamage Among European MitochondrialHaplogroups Using Phylogenetic Analysis

Jaime M. HatcherEmory UniversityEffects of Chronic Dieldrin Exposure toOrganotypic Slice Cultures of Rat Striatumand Nigra

Kerry L. HildrethDuke UniversityMolecular Mechanisms for Regulation of thePlatelet-Derived Growth Factor ReceptorBeta by Serine Phosphorylation

Renee HoUniversity of Southern AlabamaEnhancing Mitochondrial DNA Repair ofOxidative Damage as a Strategy to Delay theEffect of Aging in Neurons

Steven HobbsUniversity of ColoradoThe Role of Estrogen in Cortisol InducedBeta-amyloid Production and Toxicity

Troy A. HornbergerUniversity of Illinois, ChicagoRegulation of Protein Synthesis ThroughStretch Induced Signaling Events in AgingSkeletal Muscle

Matthew R. HoslerUniversity of Medicine and Dentistry of NewJerseyThe Role of Oxidation in the TGF- ß CataractModel

James G. JacksonUniversity of Texas Health Science Center atSan AntonioRole of the Novel Transcription FactorMRG15 in Cell Proliferation and SenescenceEscape

Hanyu (Maggie) LiangUniversity of Texas Health Science Center atSan AntonioCharacterization of Transgenic MiceOverexpressing Thioredoxin2 (Trx2)

Janelle MallettUniversity of ConnecticutEffect of Parathyroid Hormone onOsteoblast Proliferation and Apoptosis inFgf2 Knockout Mice

Julien MuffatCalifornia Institute of TechnologyCharacterization of the DrosophilaApolipoprotein D Homolog as a Novel GeneInfluencing Lifespan and Stress Resistance

Tung Hoang Ngo, Ph.D.Western University College of MedicineEffect of Dietary Fat on Androgen-independ-ent Prostate Tumor Growth in Scid Mice

Anirban PaulHoward UniversityNovel Regulators of Manganese SuperoxideDismutase Gene Transcription in Drosophila

Richard J. PerrinUniversity of Illinois at Urbana-ChampaignAnalysis of Polyunsaturated Fatty Acid-induced Modification of Alpha-synuclein, aProtein Involved in Neurodegenerative Disease

Deepa PikleUniversity of MarylandPremature Aging: A ’Defective’ Helicase-topoisomerase Interaction in DNAMetabolism

Amy PoolerMassachusetts Institute of TechnologyInvestigating Age-Related MemoryImpairment: The Role of Cholesterol inSynaptic Protein Expression and MembraneFormation in the Hippocampus

Davis C. RymanCase Western Reserve UniversityA Genome Scan for Quantitative Trait LociControlling Beta-amyloid Production andDeposition in a Transgenic Mouse Model ofAlzheimer’s Disease

Megha SatyanarayanaUniversity of Texas Southwest Medical CenterA Rapid Fluorescence-based Screen forLong Lived C. elegans Mutants

Ganesh ShankarHarvard UniversityEffects of Apolipoprotein E and a1-antichy-motrypsin on In Vivo Production andStabilization of Natural Amyloid Beta-proteinOligomers

Jason D. ShepherdJohns Hopkins UniversityThe Involvement of the Immediate EarlyGene ARC in Endocytosis of Presenilin1 andAPP Processing: Implications forAlzheimer’s Disease

Tiffany E. ShubertUniversity of North Carolina, Chapel HillEffects of Exercise on Angiogenesis in theHippocampus of Mice

Brian SilviaUniversity of ConnecticutTargeted Expression of Putative DrosophilaUncoupling Protein and its Effect onLongevity

Wook SongTexas A&M UniversityEffect of Exercise Training on Age-inducedUpregulation of the iNOS Signaling Pathwayin Skeletal Muscle

Liou SunSouthern Illinois UniversityThe Effect of Dwarfism and CaloricRestriction on Synaptophysin Expression inthe Mouse Hippocampus

Susan E. Swanberg, J.D.University of California, DavisAvian Cells In Vitro: A Model System for theStudy of Telomere Length Regulation andReplicative Senescence

2002 ScholarsTrinity J. BivalacquaTulane University School of MedicineRole of Superoxide in the Pathophysiologyof Age-related Erectile Dysfunction:Influence of In Vivo Gene Transfer ofSuperoxide Dismutase

Jinsook ChangUniversity of Texas Health Science Center atSan AntonioProfiling of Mitochondrial Proteins by 2DGel Electrophoresis in Wild Type andHeterozygous MnSOD Mice with Age

Abbie C. ConnoyWake Forest UniversityAging and the Regulation of the Interleukin-1-Receptor-associated Kinase in MurineSplenocytes

Danielle S. DayUniversity of Colorado Health Science CenterEffects of Age-related Decline in SexHormones on Resting Energy Expenditure

Cheryl (Jansen) EthenUniversity of MinnesotaProteome Analysis of Retinal Proteins

Raina T. GayTufts UniversityThe Effect of Vitamin E on SecondaryBacterial Infection Following InfluenzaInfection in Old Mice

William Y. GoUniversity of California, San DiegoElucidating the Function of NFAT5: PossibleCell Cycle Modulator in Response toOxidative Stress, UV/Ionizing Radiation andHypertonicity

24

Mark F. HaussmannIowa State UniversityHow do Long-lived Organisms DelaySenescence - Development of AppropriateModels and Techniques

Jason HinmanBoston University School of MedicineThe Characterization of Nodal Abnormalitiesin the Aging Brain

Cheng HuangWashington University School of MedicineIdentification of Genes Involved inCaenorhabditis elegans Aging

Kara JohnsonLoyola University Medical CenterEffect of Age on ß-lymphopoiesis and theMaintenance of the Mature ß CellCompartment

Nathan K. LeBrasseurBoston UniversityNeuregulin/ErbB Signaling in SkeletalMuscle: Aging & Atrophy

Sandy LiUniversity of MichiganExpression Analysis of Type II IP3 Receptorin Aging Retina

Lina LiUniversity of Alabama at BirminghamAge-related Thymic Involution in IL-12BKnockout Mice

Paul R. LockmanTexas Tech University Health Science CenterTargeted Brain Delivery of NovelNanoparticles via the Blood-brain BarrierCholine Transporter

Carrie LyonsQueen’s UniversityThe Impact of Mitochondrial Ultrastructureon Cellular Physiology

Deanna MarchioniniRush-Presbyterian-St. Luke’s Medical CenterMelatonin Treatment for Optimal GraftSurvival in an Aged Rat Model ofParkinson’s Disease

C. David MintzMount Sinai School of MedicineInvestigating the Role of Presenilin-1 at theSynapse

Jacqueline E. PaytonUniversity of Illinois at Urbana-ChampaignFunctional Analysis of theNeurodegenerative Disease-related Protein,Alpha-Synuclein

Mark RapoportNorthwestern University Medical SchoolDynamic State of Mind: Does a More PlasticCytoskeleton Prevent aß-InducedNeurogeneration in Hippocampal Neurons?

Catherine RehderVirginia Commonwealth UniversityThe Role of Chromosome Specific TelomereLength in Age-related Somatic CellAneuploidy

Rose M. ReynoldsUniversity of Illinois at Urbana-ChampaignThe Contribution of PopulationHeterogeneity to Mortality Plateaus

Ritu SainiNew York University School of MedicineGene Regulation by Interleukin-8 in CulturedKeratinocytes

Scott SalsmanOklahoma Medical Research FoundationEffect of Active Site Oxidation on the PTENTumor Suppressor

Sarah SperanzaUniversity of New England College of MedicineDevelopment of Neurosteroids as CognitiveEnhancers

Raymond W. ThompsonUniversity of South CarolinaEffect of Aging On Inflammation DuringSkeletal Muscle Regeneration FollowingFunctional Overload Induced Injury

Maria L. UrsoUniversity of MassachusettsMuscle Function, Disuse and Antioxidants inOlder Adults

Laura Volpicelli-DaleyEmory UniversityThe Effects of Chronic CholinergicStimulation on Muscarinic AcetylcholineReceptor Intracellular Trafficking andExpression

Min ZhuUniversity of RochesterTranscription Modulation by the C-terminalFragment of Amyloid Precursor Protein inNeurodegeneration

Brian M. ZidCalifornia Institute of TechnologyInvestigating the Role of Fatty Acid AmideHydrolase in Aging Using Drosophilamelanogaster

2001 ScholarsYama AkbariUniversity of California, IrvinePrimary Mechanism Underlying PresenilinMutations: Calcium Dyshomesostasis orBeta-Amyloid Formation?

Daniela-Annenelie BotaUniversity of Southern CaliforniaRegulation of Lon Protease Activity withAging and Level of Oxidative Stress

David BadreMassachusetts Institute of TechnologyNeurobiology of Cognitive Aging: HumanPrefrontal Cortex and Memory in NormalAging

Kevin J. BittermanHarvard Medical SchoolA Genetic Screen for Factors That ExtendLifespan Through Caloric Restriction Pathway

Todd A. CannonUniversity of WashingtonInvolvement of WRN Protein inAtherosclerogenesis

Lynn ChienDuke UniversityTumor Necrosis Factor Receptor Subtype-specific Signaling in Vascular SmoothMuscle Cells

Krishnan M. DhandapaniMedical College of GeorgiaMechanisms of Neuroprotection byEstrogen and SERMs

Ibtissam EchchgaddaUniversity of Texas Health Science Center atSan AntonioAging and DHEA-sulfotransferase inCholesterol and Bile Acid Homeostasis

Mark R. GavinWashington UniversityUnderstanding the Mechanism of S PhaseArrest by the Retinoblastoma TumorSuppressor Protein

Kristen J. HomesWashington UniversityElucidation of Components of the B3Integrin that are Essential for BoneResorption: A Search for Anti-osteoporosisTherapeutic Targets

Andrew C. HsiehAlbert Einstein College of MedicineThe Role of a Novel Forkhead Target Gene inRegulating Cellular Senescence

Carianne JudgeUniversity of MarylandInvestigating the Role RNase-L Plays inSenescence

Eleanor A. KnoppYale UniversityThe Effect of Aging on the Skeletal Responseto Intermittent Treatment with PTH

Amy C. LeeMassachusetts Institute of TechnologyAge-associated Changes in theInflammatory and Proliferative Response toVascular Injury

Patrick McHughUniversity of LouisvilleNeutrophil (PMN) Senescence: Can PMNsBecome Too Old to Kill?

Timothy E. MeyerWashington UniversityThe Effects of 3-month DHEA Supplementationin Older Adults on Vascular Reactivity

Gail C. O’KaneMassachusetts Institute of TechnologyExploring the Relation Between Set Shiftingand Memory Retrieval

Thomas J. ScharshmidtNortheastern Ohio University College ofMedicineAnalysis of Type IIA and IIB Splice Variantsof Procollagen in Osteoarthritis UtilizingLaser Capture Microdissection

Rodney E. ShackelfordDes Moines University of OsteopathicMedicineAtaxia-telangiectasia, Gene Therapy, and theCellular Aging Process

Alex ShpilmanFinch University of the HealthSciences/Chicago Medical SchoolImpact of the SAPK-1 Pathway on the Age-related Impairment of Adipogenesis

Faisal SiddiquiState University of New York, SyracuseNumerical Densities of Myonuclei and SatelliteCells in Muscle Fiber Tin the Aging HumanLateral Cricoarytenoid Muscle: AnImmunohistochemical and Stereological Studyusing Confocal Laser Scanning Microscopy

Bethany SlaterMount Sinai School of MedicineAlpha MSH and Aging

Christine C. SpencerUniversity of GeorgiaThe Role of Gene-gene Interactions in Aging

Michael SugarmanUniversity of California, IrvineCan Inclusion Body Myositis Be Treated witha Beta Amyloid Vaccine?

Junko TakeshitaWashington UniversityOxidative Damage of DNA: Mechanisms forCarcinogenesis

Doris M. ThamUniversity of California, DavisActions of Peroxisome Proliferator-activatedReceptor on Diabetic Vasculopathy

Isaiah TurnbullWashington UniversityEffect of Aging on the Heat Shock Responseand Subsequent Sepsis Survival

Christian Von HehnChristian-Albrechts-Universitaet, KielThe Role of Kv3.1 and its Regulation in Age-related Hearing Loss

Jill M. WeimerUniversity of RochesterA Transgenic Animal Model for the Disruptionof Lysosome/Endosome Function: ACommonality in Neurodegenerative Diseases

2000 ScholarsEric D. AgdeppaUniversity of California, Los AngelesBiological Probes for Beta-amyloid Plaquesin Alzheimer’s Disease: In Vitro Analysis ofBeta-amyloid-binding Characteristics ofDDNP Analogs

Rania Al-ShamiUniversity of DelawareRelative Levels of OPN-1 and OPN-2 ChangeDuring Aging

Xinlian ChenUniversity of Texas Health Science Center atSan AntonioThe Response of Mice that OverexpressCatalase and Cu/Zn-SOD to Oxidative Stress

Jay ChyungHarvard UniversityCharacterizing the Effects of a MucosalVaccine for Alzheimer’s Disease

25

Richard D’AlonzoSaint Louis UniversityPhysical Interaction Between OsteoblasticTranscription Factors

Rajesh DashUniversity of CincinnatiPhospholamban Phosphorylation as aCompensatory Mechanism of theEndangered Myocardium

Allison W. DobsonUniversity of South AlabamaEnhancing mtDNA Repair in Down’s andCockayne’s Syndromes

Delia GariganUniversity of California, San FranciscoMapping and Characterization of NovelLifespan Mutations in C. elegans

David GordonUniversity of ChicagoInvestigation of the Structure of BetaAmyloid Fibrils

Elise GrenierNorthwestern UniversityRegional Differences of Astrocytes in theDevelopment or Acceleration of Alzheimer’sDisease

Andreana P. HaleyUniversity of VirginiaA Magnetic Resonance SpectroscopicExamination of Hippocampal Volume and N-acetyl-aspartate Levels in Healthy Aging

Jeffrey P. HendersonWashington UniversityHalogenation of DNA by the MyeloperoxidaseSystem of Activated Phagocytes: Implicationsfor Carcinogenesis at Sites of Inflammation

Vicki KuleUniversity of MichiganCharacteristics of Disulfide Intermediate inthe Aging of Phosphoglycerate Kinase

Justine LevinRockefeller UniversityEstrogen Effect in a Mouse Model ofAlzheimer Disease

Stephen S. LinWashington UniversitySnflp Kinase and Aging in S. Cerevisiae

J. Andy MengsholDartmouth University Medical SchoolIL-1 Regulation of Collagenase-3 inOsteoarthritis

Renee MillerUniversity of RochesterGene Expression Profiling in Parkinson’sDisease

Kevin MonahanUniversity of ColoradoDo Reductions in Carotid Arterial ComplianceModulate the Age-related Decline in ArterialBaroreflex Function in Sedentary andRegularly Exercising Humans?

Bhagavathi RamamurthyPenn State UniversityThe Effect of Glycation of Myosin on the InVitro Motility of Actin with Respect to Aging

Jody L. ShortWestern University of Health SciencesEffects of Human Apolipoprotein E Isoformson Olfactory Nerve Plasticity in Mice

Jennifer E. StineUniversity of Texas Health Science Center atSan AntonioStructural Study of FALS-associated Cu-ZnSuperoxide Dismutase Mutants

David A. SunMedical College of Virginia/VirginiaCommonwealth UniversityMolecular Basis for Stroke Induced Epilepsy

Leslie P. TaoUniversity of California, Los AngelesA Progesterone-dependent Mechanism toDelay Reproductive Aging

Robert T. Turner IIIOklahoma UniversitySubstrate Specificity of ß-Secretase:Towards Design of Inhibitor Drugs

Baiping WangUniversity of WashingtonIn Vivo Analysis of the Role of FE65 inAlzheimer’s Disease

Fei-Shiuann Clarissa YangMcGill UniversityRole of Telomere-associated Senescence inWound Healing

1999 ScholarsErin K. BaehrNorthwestern UniversityLow-intensity Exercise at Night to Phase-delay Circadian Rhythms of Older Adults

Jennifer BerkeleyEmory UniversityMuscarinic Regulation of Amyloid PrecursorProtein Metabolism

Erik D. BernsteinAllegheny University of the Health SciencesRAGE, Aging and Peripheral NerveRegeneration

Wende R. BurasBoston University School of MedicineThe Role of Threonine Phosphorylation inEGFR Dysfunction with Aging

Manu ChakravartyUniversity of Texas Medical School at HoustonProliferative Capacity of Skeletal MuscleSatellite Cells with Aging

Judy Y. ChenMeharry Medical CollegeA Clinical and Molecular Genetic Analysis ofEarly-onset Parkinson’s Disease in an AsianAmerican Family

Frank A. DinennoUniversity of Colorado at BoulderFemoral Artery Intima-media Thickness:Effects of Aging and Habitual Physical Activity

Andrew DoanJohns Hopkins UniversityIdentification and Characterization ofInteracting Proteins That Modify the CellBiology and Neurodegenerative Propertiesof Presenilin 1, an Alzheimer’s Disease-linked Protein

Shawn P. GallagherUniversity of DelawareDetecting Early Glaucomatous Visual FieldLoss with Neural Networks

Joseph P. GautWashington UniversityA Myeloperoxidase-Dependent Pathway ofOxidative Damage in 1-Mehyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-inducedParkinson’s Disease

Bradley S. HensonUniversity of MichiganImpact of Parotid-sparing Radiation onXerostomia and Quality of Life in Head andNeck Cancer Patients

Kailiang JiaUniversity of Missouri at ColumbiaGenetic Study of daf-9, A Modulator of LifeSpan in C. elegans

Elizabeth KensingerMassachusetts Institute of TechnologyUncovering the Relation Between Short-term Memory and Long-term Memory

Elaine KhatodWake Forest UniversityThe Effects of Age and Exogenous Estrogenon the Synaptic Density of Layer II PrefrontalCortex: Does Estrogen Replacement IncreaseSynaptic Density in this Cognition-associatedRegion of the Old OVX Female Brown NowayX Fischer 344 Rat?

David W. KillileaUniversity of South AlabamaPhysiological Oxidant Generators AlterGenomic Integrity

Daniel E. KolkerNorthwestern UniversityCircadian Gene Expression in Young andOld Hamsters

Joseph E. Labrie IIIUniversity of MassachusettsIs U(D)J Recombinase Activity Decreased inAged Mice?

James K. LeungBaylor College of MedicineCharacterizing the MORF4-Related Gene onChromosome X (MRGX)

Janet A. MartinUniversity of California, IrvineAstrocyte Degeneration and VascularChanges in Frontotemporal Dementia

Ryan A. McTaggartColumbia UniversityAmyloid-ß and ABAD: A Convergence ofAlzheimer’s Disease and Stroke

James F. MeleThe University of Texas Health Science Centerat San AntonioThe Development of a Transgenic Model toStudy the Role of Manganese SuperoxideDismutase in Oxidative Stress

David MerrillUniversity of California San DiegoNeurodegeneration of the HippocampalFormation with Aging and Treatment withNeurotrophic Factors

Daniel W. MudrickJohns Hopkins UniversityEffects of Age on NOS2 Induction andResponse to ß-Adrenergic Stimulation inLPS and y-INF Exposed Rat Hearts

Anavelys Ortiz-SuarezUniversity of MichiganCharacterization of Expanded T-cell Clonesin Old Mice

James P. PassinaultLoyola University Medical CenterAngiogenesis and Aging

Nicholas K. PriestUniversity of GeorgiaThe Maternal Effects of Stress Resistanceand Senescence

Eric S. RawsonUniversity of MassachusettsCreatine Loading in Elderly Men

Haifeng SongUniversity of Maryland, BaltimoreAltered Responses of Aged ß Cells to CD40Stimulation

Veena ViswanathUniversity of Southern CaliforniaRole of Apoptosis in Age-relatedNeurodegenerative Disorders: Caspases andTheir Inhibition as a Potential TherapeuticIntervention

Theodor A. ZainalUniversity of WisconsinHistologic Quantitation of Age-dependentOxidative Damage in Rhesus MonkeySkeletal Muscle: Effects of Caloric Restriction

1998 ScholarsStuart K. AmateauUniversity of Maryland BaltimoreEstrogen Modulation of GlutamateNeurotransmission in the Aging Brain

Peter J. BayleyUniversity of California, San DiegoSerial Position Effects In Rats’ Spatial Memory

Louis K. ChangWashington University School of MedicineIsoform-specific Effects of ApoE on Beta-amyloid Deposition and Inflammation In Vivo

Isaac S. ChengTufts UniversityIdentification and Characterization ofCaspase(s) Responsible for the AlternativeEndoproteolysis of Presenilins DuringNeuronal Apoptosis

26

Christen M. CullenMassachusetts Institute of TechnologyHemodynamics in Aging and Alzheimer’sDisease: An fMRI Study

Limor DeutschBoston UniversityGene Transfer in the Aging Myocardial Cell

Christopher DeVryUniversity of California, Los AngelesProtein Repair in the Biology of Aging

Dena DubalUniversity of KentuckyNeuroprotective Effects of Estrogen in Aging

Melissa GillBrown UniversityEffect of D1 Receptor Modulation onMemory in Aged Mice

Gerald J. GraciaUniversity of FloridaHost Defense Against Influenza in Aged Mice

Allen HarrisonUniversity of MichiganAging and the Ubiquitination of the CD3-zetaChain

John M. HollanderUniversity of Wisconsin, MadisonAging and Antioxidant Enzyme GeneRegulation: Superoxide Dismutase Broughtto Focus

Elizabeth T. Hsiao-WeckslerUniversity of California, BerkeleyInfluence of Lower Extremity Joint Torqueson Balance Recovery by Stepping

Lyndon JosephUniversity of ArkansasWeight Loss, Exercise, and Age: Effects onInsulin Action

Vivek KaliramanUniversity of Medicine and Dentistry of NewJerseyRole of the SLX Proteins in rDNA Stabilityand Aging in Yeast

Richard KwunNew York Medical CollegeThe Use of Pulse Wave Velocity to MeasureAge-related Arterial Stiffening in the Mouse

Peter H.U. LeeBrown UniversityTissue-engineered BioArtificial MusclesTransduced with the IGF-1 Gene CanPromote Motoneuron Sprouting and MuscleFiber Innervation In Vitro

Malcolm A. LeissringUniversity of California, IrvineEffects of Presenilin-1 on Calcium Signaling

Oren LevyEmory UniversityEffects of FAD-Linked Presenilin-1 Mutationson Notch Signaling

Marisol E. LopezUniversity of Wisconsin, MadisonCharacterization of Age-associated ElectronTransport System Abnormalities andAssociated Fiber Atrophy in Rhesus MonkeySkeletal Muscle

Kevin M. OwenLoyola University Medical CenterThe Kinetics of ß-Lymphocyte Production inAged Animals

Marc D. ParadisMassachusetts Institute of TechnologyPresenilins 1 and 2: Effects ofPharmacologic Stimulation ofNeurotransmitter Receptors Coupled toPhospholipase C, Phospholipase A2, orAdenylyl Cyclase Activity on their Cleavage,Transcription and Translation

Echo V. RoweUniversity of WashingtonComplementation of 4NQO Sensitivity inSgs1 Mutant Strains of S. cerevisiae by theHuman Werner Syndrome Protein

Aileen WiglesworthUniversity of KentuckyQuantitative Assessment of Synaptic Densityin Superior Parietal Lobule in Alzheimer’sDisease

Tong ZhuCase Western Reserve UniversityAging-related Defects in Complex III ofCardiac Mitochondria

1997 ScholarsNael Al-AbdullaJohns Hopkins University School of MedicineNeocortical Brain Transplantation to ReverseNeuronal Apoptosis in the Adult LateralGeniculate Nucleus and Restore Connectivity

Kaveh AshrafiWashington University School of MedicineThe Role of Protein N-myristoylation inControlling Survival of Saccharomyces cere-visiae During Stationary Phase and CellularAging

Randall BatemanCase Western Reserve UniversityHuman Mesenchymal Stem Cell Interactionwith Endothelial Cells During In VitroAngiogenesis

Tammie BenzingerUniversity of ChicagoStabilization and Characterization of anIntermediate Conformation of the Beta-amy-loid Peptide of Alzheimer’s Disease

Mark BordenAllegheny University of the Health SciencesAge-related Effects of Fracture Non-unionTreatment Using a Novel Synthetic BoneReplacement

Connie ChenJohns Hopkins School of MedicineThe Individual Impact of Dietary Fats andAntioxidant Vitamin Supplements in the Riskof Alzheimer’s Disease

Jeff CoombesUniversity of FloridaThe Effects of Vitamin E and Lipoic AcidSupplementation on Myocardial Ischemia-reperfusion in Senescent Rats

Michael DobryanskyNew York University School of MedicineAngiogenesis and Prognosis of ColorectalCancer

Kimberley EkisUniversity of MichiganCorrelated Patterns of Epstein-Barr VirusReactivation in Elderly Humans

Sara EvansBaylor College of MedicineAnalysis of the Role of the Human Homologof an Est2 Interacting Protein in HumanTelomere Biology

Jonathan FisherWashington University School of MedicineEffects of Ovariectomy and EstrogenReplacement on Rat Skeletal Muscle

Ariel FriedmanColumbia UniversityEnhanced Interaction of Advanced GlycationEndproducts (AGEs) with Their CellularReceptor RAGE: Implications for thePathogenesis of Diabetic Neuropathy

Barry HoopengardnerUniversity of Connecticut Health CenterIdentification of a Temporally-responsiveRegion in the Genome of Drosophilamelanogaster

Scott JenkinsUniversity of Alabama at BirminghamMicrotubule-associated Protein ß as aSignal Transducer: Modulation by SignalsPresent in the Alzheimer’s Disease Brain

Terry JonesUniversity of KansasFunctional Consequences of AlteredExpression Levels and Conformation of theRyanodine Receptor Calcium ReleaseChannel in Aged Skeletal Muscle

James LeeStanford UniversityIn Vivo Target Specific Delivery ofLiposome-encapsulated Doxorubicin intoMouse Tumor Model Using MagneticResonance Guided Focused Ultrasound

Paul MackUniversity of GeorgiaTheories of Aging: A Test for the Existenceof Age-specific Mutations

Lemuel NewtonUniversity of Florida College of MedicineEnteric Immunization with RecombinantVaccinia Virus

Christopher NorrisUniversity of VirginiaThreshold for a Novel Form of SynapticPlasticity: A Link between Ca2+ Regulationand Impaired Memory During Aging

Moyosore OnifadeWashington University School of MedicineRole of Astrocytic apoE

Christopher PastoreTufts UniversityAge Effects on the Proportion and ProtectiveFunction of Circulating Endothelial CellProgenitors

Jocelyn PecceiUniversity of California, Los AngelesHeritability in the Age of Menopause

Mark SnowUniversity of Southern CaliforniaWhat is the Actual Relationship Betweendaf-12 and daf-2 in Caenorhabditis elegansAdult Longevity?

Maria TresiniAllegheny University of the Health SciencesDefect in the ras/MEK/MAP Kinase SignalTransduction Pathway in Senescent HumanCells

Jonathan WanagatUniversity of Wisconsin-MadisonMitochondrial Abnormalities in theCardiomyopathy of the Aging Rat Heart

1996 ScholarsKristin BakerTufts UniversityNeural Adaptation to Strength Training in theElderly

Alex DranovskyStony Brook Medical School, State Universityof New YorkRole of APP in Microtubule Dynamics

Michael EisenbraunUniversity of MichiganAge-sensitive T-cell Subsets Marked by P-glycoprotein: Specific Responses to aClonally Restricted Protein Antigen (PigeonCytochrome C)

Astrid GutsmannUniversity of Texas Health Science CenterDoes Overexpression of HSFI in HumanDiploid Fibroblasts Correct for the Age-relat-ed Decline in the Induction of Heat ShockProtein 70 Expression?

Nathan HallUniversity of Cincinnati College of MedicineEdema Reduction and White MatterProtection Following Treatment with aPhenylnitrone Spine Trap in Experimental ICH

Edward HueyStanford UniversityThe Intracellular Effects of Stress Hormoneson Neurons

Peter KennedyUniversity of WashingtonMechanisms of Age-dependent Loss of DNARepair Capacity in Human Brain

Steven KleopoulosTrinity CollegeManipulation of Hypothalamic NeuropeptideY Gene Expression During Aging

Shi LiUniversity California, San DiegoGlutamate Transporters and SynapticPathology in Alzheimer’s Disease

David LiebermanUniversity of California, Los Angeles School ofMedicineSecond Messenger Actions of Beta-amyloidPeptides

27

Srilakshmi MaguluriUniversity of Medicine and Dentistry of NewJerseyThe Effect of Aging on Rhythmicity

Marta MargetaUniversity of IllinoisG-proteins Involved in the Calcium CurentInhibition Induced by Substance P andNeurotensin

Ewan McNayUniversity of VirginiaDetermination of the Effects of Aging onExtracellular Brain Levels of Glucose

Brian MurphyWashington University School of MedicineRole of apoE and LRP in Neuronal Plasticity

Erik NaylorNorthwestern UniversityNovel Animal Model for Exploring the Delayof Sleep and Circadian Rhythms in the Elderly

Lemuel NewtonUniversity of Florida College of MedicineEnhancing Influenza Vaccine Effectiveness

Jason OgisteCornell University Medical CollegeRedox Regulation of Signal Transduction

Andrew RogoveState University of New York, Stony Brook+PA Mediates Microglial Activation via aNon-proteolytic Mechanism

Sheila ScovilleEastern Virginia Medical SchoolThe Impact of Menopause on PrimarySensory Neurons

Xiaoming SunUniversity of Connecticut Health CenterOptimal Stimulus Parameters for theMeasurement of Distortion ProductOtoacoustic Emissions in a Mouse Model ofPresbycosis

Gina VandenLangenbergUniversity of WisconsinRelationship Between AntioxidantSupplement Use and Risk of Age-relatedMaculopathy

Tessa WaltersThe Parkinson’s InstituteBiochemical and Immunocyochemical-stereological Analysis of Mouse NigrostriatalDegeneration after Exposure toDithiocarbamates and MPTP

Conrad WeihlUniversity of ChicagoNeuronal Gene Delivery via Adenoviruseswith Bicistronic Constructs in the Study ofSelective Motor Neuron Cell Degeneration

Amy WhitetreeUniversity of Oklahoma Health Sciences CenterThe Cell Body Response to Axotomy inAging Motor Neurons In Vitro

Wenjun ZhangUniversity of South FloridaKainate-induced Expression of MatrixMetalloproteinases in Brains from Old Rats

1995 ScholarsHarleen AhujaQueens CollegeA Genetic Approach to UnderstandingMolecular Mechanisms of Cell Death

Kaveh AshrafiWashington UniversityProtein N-Myristoylation and Cellular Aging

Jay BinderCase Western Reserve UniversityProbing of Glucose-mediated CrosslinkingSites in Y Crystallins Using Site DirectedMutagenesis

Kit Mui ChiuUniversity of Wisconsin-MadisonEffects of Age on Apoptosis of PigOsteoblast-progenitor Cell Culture

David DiLoreto, Jr.University of RochesterThe Effects of Retinal Transplantation on theAge-related Retinal Degeneration in theFischer 344 Rat

Oren FriedmanThomas Jefferson UniversityReplacement of SV40 Tantigen by IRS-1 andShe as Factors in Cellular Transformation

Joshua GarrenBrown UniversityA Model for Studying Activity-drivenSynaptic Plasticity

John HeymachStanford University Medical SchoolThe Targeting of Neurotraphins and TheirReceptors by Neurons

Alon KahanaUniversity of ChicagoA Genetic and Molecular Investigation ofTelomere Structure and Function

Christopher KirkUniversity of MichiganRole of 14-3-3 Proteins in T-cell Activation:Affects on Aging

Leslie PejicUniversity of Illinois at ChicagoMechanisms of Neuron Aging

Michael RogersKent State UniversityMyosin Heavy Chain Altercations DuringEight Weeks of Heavy Resistance Training inActive Elderly Females

Neha ShahUniversity of Florida College of MedicineAging and NPY Expression After AAV-Mediated Gene-delivery in Brain

Jordan ShinUniversity of Alabama at BirminghamFibroblast/Growth Factor ModulatesPeroxynitrite-induced Apoptosis

Michael TothUniversity of Maryland at BaltimoreEnergy Metabolism in Congestive HeartFailure Patients

1994 ScholarsRupinder BalCase Western ReserveBiological Effects of Protein Glycation

Deborah FerringtonUniversity of KansasThe Role of Protein Turnover in Aging of theSarcoplasmic Reticulum Ca-ATPase

Timothy HughesBaylor College of MedicineInitial Work Toward Characterization of theSDI-3 Gene

Van Khank HuynhTufts University School of MedicineEffect of Aging on the In Vitro Formation ofHaloperidol Pyridinium, a PotentiallyNeurotoxic Metabolite of Haloperidol

Mark KadrofskeMichigan State UniversityRegulation of Expression of a Lectin inSenescent Human Fibroblasts

Soo-hyun KimUniversity of Medicine and Dentistry of NewJersey Graduate School of Biomedical ScienceCharacterization of Growth Suppressor Geneon Human Chromosome 6

2002 FellowsJulie Bynum, M.D., M.P.H.Johns Hopkins UniversityAnalysis of Expenditures for AD Patients

Lisa Honkanen, M.D.Weill Medical College of Cornell UniversityExternal Hip Protectors

Grace Y. Jenq, M.D.Yale University School of MedicineDetermining Adherence to a Pain ManagementModel in the Nursing Home Setting

Jennifer M. Kapo, M.D.University of PennsylvaniaHow Can We Improve Services for theElderly at the End-of-Life?

Reena Karani, M.D.Mount Sinai School of MedicineAn Evidence-based Unfolding Case with aLinked Objective Structured ClinicalExamination (OSCE)

Kevin KingUniversity of MissouriGenetic Interactions of daf-2 with daf-3 &daf-5 with Respect to Life Span & LarvalDevelopment in C. elegans

Xiao SuUniversity of Alabama at BirminghamFAS Apoptosis and HEPH Function with Aging

Gina Uken TrebilcockUniversity of ArkansasRole of Transcription Factor Nuclear FactorKappa ß in Aging

Melissa WilliamsUniversity of Texas Health Science Center atSan AntonioConstruction of a Transgene to be Used inthe Production of Transgenic Mice ThatOverexpress Catalase

Xiaowei XuBowman Gray School of Medicine at WakeForest UniversityEffects of Age on IGF-signal Transduction

Richard YuNorthwestern University Medical SchoolMolecular Response to Inflammation andAging

AFAR/The John A. Hartford FoundationAcademic Fellowship Program in GeriatricMedicine and Geriatric Psychiatry

One- to two-year fellowship awards supported the development geriatricand geriatric psychiatry fellows who addressed complex basic, clinical, and health services research or educational projects. Sponsored by The John A. Hartford Foundation. This program was active from 1999 to 2002.

Victor J. Legner, M.D.University of Washington School of MedicineThe Importance of Medical Comorbidity andPreoperative Functional Status in PredictingFunctional Decline in Older AdultsUndergoing Nonemergent Surgery

Cari R. Levy, M.D.University of Colorado Health Sciences CenterHospital versus Nursing Home:Determinants of Site and Cost of DeathAmong Nursing Home Residents

Robert J. Pignolo, M.D., Ph.D.University of Pennsylvania School of MedicineThe GNAS1 Gene as a Regulator ofOsteoblast Differentiation and MolecularTarget for the Stimulation of Bone Formation

James L. Rudolph, M.D.Harvard Medical SchoolRelationship of Intraoperative Trans CranialDoppler (TCD) Output to Delirium in PatientsUndergoing Coronary Artery Bypass Graft(CABG) Surgery

28

David Sengstock, M.D., M.S.University of MichiganPredictors of Orthostatic Hypotension: Non-invasive Arterial Stiffness Measurement

Crystal Simpson, M.D., M.H.S.Johns Hopkins UniversityFactors Influencing Outcomes for OlderAfrican-American Women with Asthma

Daniel E. Wollman, M.D., Ph.D.Mount Sinai School of MedicinePerfusion MRI of Parietotemporal Cortexand Hippocampus in Alzheimer’s Disease

Laurel B. Yates, M.D.Harvard Medical SchoolBeyond Bone Density: A Prospective Studyof Hip Geometry and Structural Differencesas Predictors of Hip Fracture Among ElderlyLong-term Care Residents

2001 FellowsHoward J. Aizenstein, M.D., Ph.D.University of Pittsburgh Medical CenterFunctional MRI Investigations of theFrontostriatal System in Late-life Depression

Robert C. Blackmon, M.D.Medical College of VirginiaDoes Reading Religious Literature ReduceCortisol Secretion in Elderly Patients?

Cynthia M. Boyd, M.D., M.P.H.Johns Hopkins University School of MedicineHospitalization and Disability in a Cohort ofModerately to Severely Disabled OlderWomen

Cynthia J. Brown, M.D.Yale University School of MedicineImmobility in the Hospitalized Elderly Patient:Prevalence and Impact on Functional Decline

Bruce Carruthers Bonnell, M.D.Harvard Medical SchoolMedications as Risk Factors for Falls Amongthe Hospitalized Elderly

Yohannes Endeshaw, M.D., M.P.H.,F.A.C.P.Emory University School of MedicineIs Obstructive Sleep Apnea More Prevalentin Older Adults with Nocturia Compared toOlder Adults without Nocturia?

Karen E. Glasser Scandrett, M.D.Harvard Medical SchoolMeasures of Religiosity in a Frail and AgedJewish Population: Validity and Application

Michele Y. Lee, M.D.University of New MexicoHospice/Palliative Care Training of FamilyPractice Residents

Felice LePar, M.D.University of Pennsylvania School of MedicineOlder Cancer Patients’ Attitudes TowardParticipation in Research

Stacie Levine, M.D.Mount Sinai School of MedicineRisk Factors and Outcomes in HospitalizedAdults over Age 85

Karol Mansilla, M.D.Medical College of VirginiaMechanisms of Relative Hypogonadism inAging Men

Stacy Meyer Fischer, M.D.University of Colorado Health Science CenterThe Effects of Palliative Care Education onResidents’ Knowledge, Attitudes, and Careof Patients

Jennifer D. Moore, M.D.Duke University Medical CenterA Study to Determine Specific Barriers to aGood Death at a Tertiary Care, AcademicMedical Center and to Initiate Change

Jennifer Rhodes-Kropf, M.D.Mount Sinai School of MedicineHow Interns Learn to Care For Dying Patients

Robert G. Riekse, M.D.University of Washington School of MedicineVascular Risk Factors in Alzheimer’s PatientsWith and Without Cerebral VascularInfarctions: A Clinico-neuropathologicalStudy

Xiangrong Shao, M.D.University of Maryland School of MedicineLongitudinal Assessment of FunctionalPerformance in Older Peripheral ArterialDisease

Lisa M. Walke, M.D.Yale University School of MedicineLongitudinal Study of the Burden ofSymptoms Among Community DwellingElders with Terminal Diseases

Chia-Ying Wang, M.D.University of Texas Southwestern MedicalCenterThe Effect of Potassium Citrate on CalciumBalance and Bone Metabolism in HealthyElderly Women\

Heidi R. Wierman, M.D.University of Rochester School of MedicineNovel Methods for Functional Assessment

2000 FellowsJulie Beales, M.D.Medical College of VirginiaDoes the Resident Assessment InstrumentImprove Identification and Treatment ofPressure Ulcer or Falls

Malaz Boustani, M.D.University of North CarolinaClinical Trial of the Effect of Donepezil onAggressive Behavior in InstitutionalizedPersons with Moderate/Advanced Dementiaand Severe Behavioral Problems

Donna M. Brady Raziano, M.D., M.B.A.University of PennsylvaniaDo ACE Units Work?

Jennifer B. Breznay, M.D.Mount Sinai School of MedicineCommunication Among Health Professionalsin the Home Care Setting

Cynthia M. Carlsson, M.D.University of Wisconsin Medical School atMadisonThe Effect of Folic Acid Supplements onEndothelial Function in Older Adults withHyperhomocystinemia

Cathleen Colon-Emeric, M.D., M.H.ScDuke University Medical CenterImproving Primary and Secondary FracturePrevention in Elderly

Geraldine Fabregas, M.D.University of Connecticut Health CenterThe Effects of Testosterone on CognitiveFunction in Men with Early Cognitive Decline

Helen M. Fernandez, M.D.Mount Sinai Medical CenterHouse Staff Awareness of their OlderInpatients’ Risks for Developing ’Hazards ofHospitalization’

Julie K. Gammack, M.D.University of WashingtonDevelopment of an Expanded GeriatricCurriculum for Internal Medicine Residentsand Medical Students at the University ofWashington Medical Center

Wendolyn S. Gozansky, M.D., M.P.H.University of Colorado Health Sciences CenterMechanisms of Visceral Fat Accumulation inOlder Women

Mitchell T. Heflin, M.D.Duke University Medical CenterScreening for Occult Malignancy in the Elderly

Cynthia Holzer, M.D.University of CincinnatiDo Beliefs and Attitudes about DementiaCreate Barriers to Appropriate PreventiveCare?

Peifeng Hu, M.D., Ph.D.University of California, Los Angeles School ofMedicinePathophysiologic Mechanisms for LowSerum Cholesterol and High MortalityAssociation in the Elderly Population

Lona Mody, M.D.University of MichiganClinical Outcomes of Community AcquiredPneumonia in the Elderly: Importance ofFunctional Status

Karen A. Morgan Blackstone, M.D.Harvard Medical SchoolThe Response of Elders with ImpairedBladder Emptying to PharmacologicTreatment for Urge Incontinence

Maj-Stina L. Rudolph, M.D.University of California, Los AngelesA Randomized, Double-blind, Placebo-con-trolled Study of S-adenosylmethionine in theTreatment of Alzheimer’s Disease

Joseph Shega, M.D.University of ChicagoEnteral Nutrition - Who Should We PEGnext? Reasons for Percuteneous EndoscopyGastrostomy Tubes in Endstage DementiaPatients

Dellara F. Terry, M.D., M.P.H.Harvard Medical SchoolNew England Centenarian Offspring Study

Michi Yukawa, M.D.University of WashingtonInvoluntary Weight Loss in the Older Adults:The Influence of Cytokines and Leptin

1999 FellowsShiraz S. Ahmed, M.D.University of Washington School of MedicinePhysical Function and Aging: TherapeuticPotential of Estrogen and Testosterone

Ali Ahmed, M.D.University of Alabama at BirminghamAssociation of Hospital Care Quality withHeart Failure Mortality and Readmissions

Jacob Blumenthal, M.D.University of Maryland School of MedicineThe Neuropeptide Y1-Y5 Receptor and itsRelationship to Obesity and Diabetes Mellitus

Stephen Bonasera, M.D., Ph.D.University of California, San Francisco5 HT Receptor Subtypes: Molecular andBehavioral Approaches to Study theRegulation of Posture and Locomotion

Ursula Braun, M.D.Baylor College of MedicineA Brief Cognitive Behavioral Intervention toImprove Functioning in Elderly Patients withChronic Obstructive Pulmonary Disease

Jessica L. Israel, M.D.Mount Sinai School of MedicineBreaking Bad News to Older Adults

Laurie L. Lavery, M.D.University of PittsburghAre Long-term Care Needs Predicted byScreening for Executive Control Dysfunction?

Cathy Lee-Chopra, M.D.University of MichiganEffect of Raloxifene on Insulin Sensitivity inPostmenopausal Women

Erik J. Lindbloom, M.D.University of Missouri at ColumbiaThe Missouri Elder Mistreatment Fatality Study

James M. Martau, M.D.University of ColoradoEvaluation of Nursing Home Quality Sincethe Implementation of the ResidentAssessment Instrument

William G. Seavey, M.D. , M.P.H.University of California, DavisEvaluation of a Community-based TelephoneIntervention to Increase Physical ActivityAmong Seniors

29

2005 ScholarsAlan BengtzenEmory University

Ariel BuluaMount Sinai School of Medicine

Olatubosun ChinwokwuSaint Louis University

Neela DasguptaJohns Hopkins School of Medicine

Ohm DeshpandeCornell University

Sharon EngelEmory University

David FishUniversity of New England College of Medicine

Andrew FisherUniversity of Pittsburgh School of Medicine

Michael FordCornell University

Daniel FreedbergHarvard Medical School

Molly FuentesUniversity of Michigan Medical School

Gina FujikamiJohn A. Burns School of Medicine at theUniversity of Hawaii at Manoa

Shanti GaneshDuke University School of Medicine

Matthew GarrettCase Western Reserve University

Benjamin GoldsmithMount Sinai School of Medicine

Elizabeth GoodmanWashington University School of Medicine

Jacqueline GreenEmory University

Joy Guerrieri-BangUniversity of New England College of Medicine

Nitin GuptaUniversity of Michigan

Elizabeth HarlowEmory University

Ben HarrisMount Sinai School of Medicine

John HopkinsUniversity of North Carolina at Chapel Hill

David HorowitzJohns Hopkins University School of Medicine

Brian HoustonEmory University

Kathleen KhongNorthwestern Feinberg School of Medicine

Sandy LiangMount Sinai School of Medicine

Kyauna MillerCase Western Reserve University

Margaret MoscatoEmory University

Anjali NigalayeUniversity of Chicago

Shantanu NundyJohns Hopkins University School of Medicine

Theodore PasqualiUniversity of California, Los Angeles

Laura Raducha-GraceUniversity of Pittsburgh

Simha RavvenTulane University School of Medicine

Brandon RobertsCase Western Reserve University

Shawn RosenUniversity of Rochester School of Medicine

Alexandra ShawMount Sinai School of Medicine

Megan SkibitskyUniversity of California, Los Angeles

Lon SteinbergAlbert Einstein College of Medicine

Malini SurMount Sinai School of Medicine

Ryan TakenagaJohns Hopkins University School of Medicine

Ezra TeitelbaumMount Sinai School of Medicine

Christie TungCase Western Reserve University

Brant UlleryCornell University

Ryan UngaroMount Sinai School of Medicine

Deborah WeenerUniversity of Michigan

Daniel WeiCase Western Reserve University

Victor WuEmory University

Priscilla YeeJohn A. Burns School of Medicine at theUniversity of Hawaii at Manoa

Jacqueline YuenUniversity of Michigan Medical School

Andrea ZapedaUniversity of Michigan

David ZinnBrown University

2004 ScholarsYachna AhujaCase Western Reserve University

Hannah H. AlphsJohns Hopkins University

Kathryn A. ArtisMount Sinai School of Medicine

Donald M. BanikUniversity of New England College of Medicine

Aisha BaqaiCornell University

Russell BergerMount Sinai School of Medicine

Gwen BernackiState University of New York, Buffalo

Laurel E. BlackmanUniversity of North Texas Health ScienceCenter- Texas College of Osteopathic Medicine

Brittany N. BohincNortheastern Ohio Universities College ofMedicine

Yasmin BootwalaBaylor College of Medicine

Catherine BuellDrew University/University of California, LosAngeles

Julie BurkeSaint Louis University School of Medicine

Joel EscobedoUniversity of Michigan

Anne E. FinefrockUniversity of North Carolina at Chapel Hill

Maximilian Gomez-TrochezMount Sinai School of Medicine

Matthew HansenCase Western Reserve University

Maryam HaqueDrexel University College of Medicine

Lianne HiranoYale University

Joey Y. KohatsuUniversity of Hawaii

Melissa H. KujawskiMount Sinai School of Medicine

Margaret W. LeungUniversity of California, San Diego

Cathy LiuEmory University

Jeffrey LohCornell University

Aleicia R. MackOklahoma State University

Kristin K. MartinOklahoma State University

Loren L. MartinezOhio State University College of Medicine andPublic Health

Matthew MeiCase Western Reserve University

Meredith J. MonteroUniversity of Michigan

Leah Y.K. NakamuraUniversity of Hawaii

Claude NguyenMedical College of Wisconsin

Barbara C. OverendEmory University

Medical Student Summer Research Trainingin Aging Program

(formerly known as the Medical Student Geriatrics Scholars Program)

Eight- to twelve-week awards encourage medical students — particularlybudding researchers — to undertake research projects and consider a careerin geriatrics. AFAR collaborates with the NIA and several foundations to continue and strengthen the original Hartford/AFAR Medical StudentGeriatric Scholars Program. Current sponsors include: National Institute onAging, The John A. Hartford Foundation, The William Randolph HearstFoundation, The Cleveland Foundation, Cardinal Health Foundation, LillianR. Gleitsman Foundation, Community Health Foundation of Western &Central New York, The New York Community Trust and an anonymous donor.The Fan Fox and Leslie R. Samuels Foundation was a sponsor from 2000-2003.

30

Hasra K. PhillipState University of New York, Upstate MedicalUniversity

Lhasa RayAlbert Einstein College of Medicine

Donna J. RoybalUniversity of California, Los Angeles

Sima ShahCase Western Reserve University

Marc P. SimpaoUniversity of Texas Health Science Center atSan Antonio

Anthony N. SireciJohns Hopkins University

Risa SmallMount Sinai School of Medicine

Amir SoumekhMount Sinai School of Medicine

Hana TakusagawaMount Sinai School of Medicine

Joseph TangMount Sinai School of Medicine

Sarah K. TigheJohns Hopkins University

Elizabeth H. TsaiUniversity of Medicine and Dentistry of NewJersey School of Osteopathic Medicine

Veronica VasquezCornell University

Giorgio VenezianoCase Western Reserve University

Pauline WuUniversity of Medicine and Dentistry of NewJersey School of Osteopathic Medicine

Cong-Zhi Cecile ZhaoMedical College of Wisconsin

2003 ScholarsCrystal L. AdamsUniversity of Texas Health Science Center atSan Antonio

April AlfordBaylor College of Medicine

Jonathan AustrianCornell University

Lisa M. BoweOhio State University

Daniel J. BurdickJohns Hopkins University

Michelle M. CabreraUniversity of Maryland School of Medicine

Shannon M. CampbellOhio University College of OsteopathicMedicine

Connie ChangCornell University

Joseph C. ChiangMount Sinai School of Medicine

Anne K. ChungUniversity of Arizona

Jarrod CollingsUniversity of North Texas Health ScienceCenter

Luis G. CruzUniversity of Hawaii

Kirsten DacalUniversity of Pittsburgh

Dilsher S. DhootChicago Medical School

Kerry A. DoneganMount Sinai School of Medicine

Margaret DonlonUniversity of Rochester

Steven D’SaUniversity of Michigan

Rachel FogelJohns Hopkins University

Michael C. ForneyCase Western Reserve University

Katherine FreemanNortheastern Ohio Universities College ofMedicine

Ewina FungUniversity of California, Los Angeles

Matthew R. GarrettCase Western Reserve University

Anne D. HalliUniversity of Alabama, Birmingham

Mary J. HessertUniversity of New England College ofOsteopathic Medicine

Christopher A. JonesJefferson Medical College

Beth H. JusticeEmory University

Christin KnowltonState University of New York, Stony Brook

Thomas A. LeesonUniversity of New England College ofOsteopathic Medicine

Serena LoUniversity of Hawaii

Monica G. MajmundarEmory University

Danielle A. McClellanSaint Louis University

Daniel F. MotterPhiladelphia College of Osteopathic Medicine

C. Ariel NasonBoston University

Anoma NelloreUniversity of Pennsylvania

Michael NystromUniversity of California, Los Angeles

Monica I. OshitaUniversity of Hawaii

Joon Hong ParkUniversity of Virginia School of Medicine

Schonze F. Peck-Del PozoJohns Hopkins University

Angela S. PengUniversity of Texas Health Science Center atSan Antonio

Christopher H. PerkinsBaylor College of Medicine

Tracy PrachthauserMedical College of Wisconsin

Carl T. Ratliff, Jr.Ohio University College of OsteopathicMedicine

Elizabete M. SantosUniversity of New England College ofOsteopathic Medicine

Sarah SchellhornCornell University

Shauna SchwartzState University of New York, Stony Brook

Sona S. ShahEmory University

Janet E-H ShuBrown University

Jennifer N. StojanUniversity of Michigan

Kathleen A. WalkerMedical College of Ohio

Melanie C. WuerstleUniversity of California, Los Angeles

Anthony YinSaint Louis University

Beata ZubrowskiPhiladelphia College of Osteopathic Medicine

2002 ScholarsStephanie J. AndersonSaint Louis University

Srilatha AtluriIndiana University School of Medicine

Isabel BalderasHarvard University

Amy BaxiSaint Louis University

Julia B. BeckerUniversity of Michigan

Pablo E. BedoyaEmory University

Michael A. BlairUniversity of Maryland, Baltimore

Jessica K. BlandUniversity of Texas Health Science Center atSan Antonio

Jonathan BlauState University of New York, Stony Brook

Catherine A. BluteauUniversity of Michigan

Brooke N. BosleyUniversity of Pittsburgh

Kathryn E. CallahanMount Sinai School of Medicine

Amy CarrollEmory University

Richard B. Carter, Jr.Baylor College of Medicine

Yamileth R. Cazorla-LancasterUniversity of North Texas Health ScienceCenter

Kenneth V. ChongNew York Medical College

Jessica ColburnUniversity of Pittsburgh

Alan CoonSaint Louis University

Rahul DesikanBoston University

Kimiko Domoto-ReillyNew York Medical College

Lanelle DulloogUniversity of Hawaii

Paul EdwardsUniversity of Arkansas

Michael EhrlichJefferson Medical College

Rebecca EpsteinIndiana University

31

Tina FanMount Sinai School of Medicine

Laura FanningCornell University

Alla FeldbargCity University of New York Medical School

Scott J. GenshaftCase Western Reserve University

Lisa GiuliCornell University

Sheena GleasonSaint Louis University

Andrew GodbeySaint Louis University

Karim GokalEmory University

Mark L. GrippMount Sinai School of Medicine

Divya GuptaNorthwestern University Medical School

Nancy HanOhio State University

Salma HaqueLouisiana State University

Lindsey HartmannUniversity of Nebraska

Peyton L. HaysCornell University

Hebah M.S. HefzyNortheastern Ohio Universities College ofMedicine

Jeffrey S. HighfillUniversity of Pittsburgh

Susan A. HodesUniversity of California, Irvine

Julia HsuBoston University

Tracy N. HuynhBoston University

Kelly J IshizukaOhio State University

D. Krysten JamesUniversity of Texas Health Science Center atSan Antonio

Beverly K. JohnsonBrown Medical School

Elizabeth A. JohnsonMedical College of Wisconsin

Rebecca JonesUniversity of Alabama, Birmingham

Abha KhandelwalOhio State University

Rose KhavariUniversity of Texas Medical Branch

Heidi A. KoernerUniversity of South Dakota

Izabela KoprowskaState University of New York, Downstate

Meenal G. KulkarniNortheastern Ohio Universities College ofMedicine

Lawrence D. LazarUniversity of California, Los Angeles

Andrew B. LeeWashington University

Wei Wei LiSophie Davis School of Biomedical Educationat the City University of New York

Elaina E. LinJohns Hopkins University

Nicole LonganeckerVanderbilt University

Aisha MacedoMount Sinai School of Medicine

Anne ManiJohns Hopkins University

Kara B. MarkhamUniversity of Michigan

Veronica Mendoza-JenkinsUniversity of Washington

Aaron K. MoryThomas Jefferson University

Megan B. MuilenburgUniversity of North Dakota

Jae H. ParkJohns Hopkins University

Atisha PatelBaylor College of Medicine

Avni PatelUniversity of Pittsburgh

Oscar E. PenateUniversity of Washington

Carmel PersonUniversity of Louisville

Joshua D. PhillipsUniversity of Nebraska College of Medicine

Christine PinedaUniversity of Washington

Angela PoppeDuke University

Rajeev RaghavanOhio State University

Kristen N. RiceUniversity of Colorado

Jeanne B. RobinsonBaylor College of Medicine

Carmela RocchettiRobert Wood Johnson Medical School at theUniversity of Medicine and Dentistry of NewJersey

Bunja RungruangUniversity of Alabama, Birmingham

Amy RybakOhio University College of OsteopathicMedicine

Marja Samenfeld-SpechtMount Sinai School of Medicine

Christopher SciortinoCase Western Reserve University

Karen ShaharBaylor College of Medicine

Jeremy SheltonCornell University

Sara M. ShunkwilerUniversity of Iowa

Stephanie A. SiegOhio University College of OsteopathicMedicine

Gabriel K. SilvermanUniversity of Pittsburgh

Marc P. SimpaoUniversity of Texas Health Science Center atSan Antonio

Toby SmithWestern University

Lauren SnowMount Sinai School of Medicine

Tien-I Karleen SuUniversity of California, Los Angeles

Demian SzyldMount Sinai School of Medicine

Tomoko TagawaFinch University/Chicago Medical School

Connie K. TangOhio State University

Monica L. TegelerSaint Louis University

Katheryn ThomasEmory University

Justin ToState University of New York, Stony Brook

Carmen A. TraywickEmory University

W. Jeff TriffoBaylor College of Medicine

Jadwiga J. TrutyUniversity of California, Los Angeles

Christopher VernonWestern University of Health Sciences

Naveed WagleChicago Medical School

Dexter WongBoston University

Irene WuUniversity of Medicine and Dentistry of NewJersey

Brett YamaneUniversity of Hawaii

Sallis YipUniversity of Hawaii

Chung Chi YuAlbert Einstein College of Medicine

2001 ScholarsJennifer N. AlzosWeill Medical College of Cornell University

Suzanne V. ArnoldOhio State University

Karen AuUniversity of Pittsburgh

Sunyata AustinOhio University

Sarah BabineauBrown University

James F. BartscherWeill Medical College of Cornell University

Michon BechampsEastern Virginia Medical School

Paula BeckerSaint Louis University

Robert BercovitchBrown University

Christina BertaoUniversity of Hawaii

Lindsay-Rose BoyntonUniversity of Michigan

Lynsey E. BrandtUniversity of Pittsburgh

Shu-Hong Holly ChangJohns Hopkins University

Elaine ChengWeill Medical College of Cornell University

Sze Mei ChungUniversity of Hawaii

Calandra DiamondWestern University

Marcie DreisbachOhio State University

32

Justin O. EndoUniversity of Nebraska

Joshua T. EvansSaint Louis University

Martin EversMount Sinai School of Medicine

Jessica A. EvertOhio State University

Elizabeth FabreSaint Louis University

Cory R. FraserUniversity of Hawaii

Marissa E. GarzaUniversity of North Texas Health ScienceCenter- Texas College of Osteopathic Medicine

David GeistYale University

Katherine E. GrecoEmory University

David HalpernWeill Medical College of Cornell University

Daena HellerState University of New York, Downstate

Amanda M. HoughUniversity of Michigan

Rania IbrahimWestern University

Christine JensenUniversity of Washington

Leslie JuddUniversity of California, Los Angeles

Sammy S.W. KangUniversity of Maryland

David KesslerMount Sinai School of Medicine

Melissa D. KoehlerUniversity of North Texas Health ScienceCenter-Texas College of Osteopathic Medicine

Kimberly A. KregoskiWayne State University

Jennifer M. Krejci-ManwaringUniversity of Texas, Houston

Aileen LangstonBaylor College of Medicine

Emily E. LazarouUniversity of Texas Health Science Center atSan Antonio

Bryan S. LeeWashington University

Cheri LengUniversity of Washington

Diane M. LewisState University of New York, Stony Brook

Lesley L. LiuUniversity of Kansas

Jennifer G. MagalongMidwestern University

Sterling L. MalishUniversity of Hawaii

Lara MarcuseAlbert Einstein College of Medicine

Susan E. MerelUniversity of Chicago

Terrace R. MuchaOhio State University

Sara K. PasqualiDuke University

Vasum Sri Sampath PeirisUniversity of Vermont

Kenan PenaskovicUniversity of Alabama, Birmingham

Mariah A. QuinnWeill Medical College of Cornell University

Seth ResnickMount Sinai School of Medicine

Frederick C. RoedigerWeill Medical College of Cornell University

Tara SanftMedical College of Wisconsin

Jennifer SardoneOhio State University

Lewis SatterwhiteEmory University

Jennifer N. SchwartzhoffEmory University

Louisa ShairState University of New York, Downstate

Melissa J. ShermanUniversity of Pittsburgh

Rebecca StarrState University of New York, Downstate

Joshua R. SteinermanState University of New York, Downstate

Heather C. TauschekWeill Medical College of Cornell University

Gregory L. TaylorHoward University

Bob ThongUniversity of Washington

Emily TrianaBaylor College of Medicine

George C. TsaoWestern University

Kathleen T. UnroeOhio State University

Sandra D. ValeUniversity of Texas Health Science Center atSan Antonio

Sarah J. Van EppUniversity of Nevada, Reno

Nicholas J. Van WagonerUniversity of Alabama, Birmingham

Margaret S. VandewaterEmory University

Karen H. WangBaylor College of Medicine

Michelle D. WaughUniversity of Texas Health Science Center atSan Antonio

Andrew WongWeill Medical College of Cornell University

Jennifer YatesSaint Louis University

2000 ScholarsDavid AaronsonMount Sinai School of Medicine

Daniel E. AbbottUniversity of Washington

John AbbottEmory University

Craig AlguireUniversity of Michigan

Tresa Almy-AlbertUniversity of Rochester

Stefen M. AmmonUniversity of Colorado Health Sciences Center

Suzanne V. ArnoldOhio State University Health Sciences Center

Morad AskariUniversity of Pittsburgh

Amsalu BizunehEmory University

Barbara M. BlumerUniversity of Kansas

Holly N. BurfordUniversity of Alabama, Birmingham

Carol Y. ChangWestern University of Health Sciences

Janet J. ChiehRobert Wood Johnson Medical School at theUniversity of Medicine and Dentistry of NewJersey

Ji-Eun Susana ChoiAlbert Einstein College of Medicine

Neil M. ColemanUniversity of Kansas

Kathleen M. CoyleJefferson Medical College

Maria E. DudaWeill Medical College of Cornell University

Michael EinsteinMount Sinai School of Medicine

Martin EversMount Sinai School of Medicine

Michael FangNorthwestern University

Parisa FarhiUniversity of Pittsburgh

Kelly Ann GallinaNortheastern Ohio Universities

Katherine S. GarmanDuke University

Margaret H. GenovesiMount Sinai School of Medicine

M. Mehdi GhajarniaUniversity of Pittsburgh

David GidsegWeill Medical College of Cornell University

Sukara GregoryOhio State University

Rhea A. HartleyUniversity of Kansas

Jacquelyn HartzlerEmory University

Douglas E. HoltUniversity of Pittsburgh

Andrea HsiaUniversity of Miami School of Medicine

Laura HurstOhio State University

Tamara IsakovaSophie Davis School of Biomedical Educationat the City University of New York

Catherine E. JohnsonWeill Medical College of Cornell University

Eric N. KagarukiOhio University College of OsteopathicMedicine

Reiko KayashimaUniversity of Hawaii

Benjamin KimNorthwestern University

Eleanore T. KimWeill Medical College of Cornell University

33

Kristen M. KiserUniversity of Washington

Deborah A. KoehnMedical College of Virginia

Anna KovalszkiUniversity of Michigan

Katherine M. KrajewskiWayne State University

Jennifer M. Krejci-ManwaringUniversity of Texas, Houston

Anjuli KumarCornell University

Kindra LarsonUniversity of Washington

Emily E. LazarouUniversity of Texas Health Science Center atSan Antonio

Aaron LearOhio State University

Paula M. Lee-ValkovBaylor College of Medicine

Shelley G. LenamondUniversity of North Texas Health ScienceCenter

Robin LevensonIndiana University

Cecily LingUniversity of Hawaii

Jeffrey LiuWeill Medical College of Cornell University

Esther LuMount Sinai School of Medicine

Amanda F. LuceroMount Sinai School of Medicine

Edna MaUniversity of Colorado

Thomas J. MayUniversity of North Texas Health ScienceCenter

John P. MurrayDuke University

Lyssa N. OchoaBaylor College of Medicine

Heather C. O’DonnellWashington University

Clifton L. PageOhio State University

John J. PalmieriMount Sinai School of Medicine

Amy M. ParishUniversity of Kansas

Camille PedigoEmory University

Pam R. RajendranBoston University

Timothea RyanUniversity of Pittsburgh

Roland I. SaavedraFinch University Medical School/The ChicagoMedical School

Amit A. ShahBaylor College of Medicine

Chelsea SheppardSaint Louis University

Kelly A. ShimabukuroMount Sinai School of Medicine

Amy SimonMCP Hahnemann University

Kimberly SiuUniversity of Hawaii

Danielle SkirchakUniversity of Kansas

Adam H. SkolnickBrown University

Michael SmithSaint Louis University

Jalal Soltanian-ZadehOhio University College of Medicine

Sophie D. SteinRobert Wood Johnson Medical School at theUniversity of Medicine and Dentistry of NewJersey

Ik Hyun SungMCP Hahnemann School of Medicine

Henry TangWestern University of Health Sciences

Phu Binh ThaiEmory University

Leila C. ThanasoulisLouisiana State University

Katheryn J. ThomasEmory University

David E. TraulMedical College of Ohio

Alexander C. TsaiCase Western Reserve University

Sing TsaiUniversity of Pittsburgh

Scott TurnerSaint Louis University

Asit A. VoraUniversity of South Carolina

Brent R. WeedUniversity of Nevada

James B. WhiteUniversity of Alabama, Birmingham

Michael WhiteUniversity of North Texas Health ScienceCenter

Shawn WilkerCase Western Reserve University

Deborah C. YehHarvard University

Jeanette YuNorthwestern University

Lawrence ZeidmanNorthwestern University

1999 ScholarsAndrew BohmartMount Sinai School of Medicine

Kari L. CaseUniversity of Washington

Joy T. CatolicoOhio State University

Monique ChangMount Sinai School of Medicine

Anna I. ChehUniversity of California, Los Angeles

Edwin S. ChenMedical College of Ohio

David CognettiUniversity of Pittsburgh

Rebecca N. CohenMount Sinai School of Medicine

Nathaniel A. DavenportUniversity of Washington

Lucy M. DouglassUniversity of Washington

Laura N. FrainHarvard University

Benjamin J. FriedmanFinch University Medical School/ChicagoMedical School

Mark GamberUniversity of North Texas Health ScienceCenter

Jennifer GoerbigUniversity of Michigan

Amy GrossAllegheny University of the Health Sciences

Jeffrey A. GusenoffJohns Hopkins University

Sandra P. GutierrezOhio University College of OsteopathicMedicine

Catherine D. HoangChicago Medical School

Craig J. JohnstonUniversity of Washington

Hannah T. JordanMount Sinai School of Medicine

Padmini KaushalUniversity of Vermont

Michelle KeithBaylor College of Medicine

Emmalee KennedyNorthwestern University

Dorothy P. KhongUniversity of California, Riverside

Gene KimIndiana University School of Medicine

Raymond KlugFinch University Medical School/ChicagoMedical School

Aileen LangstonBaylor College of Medicine

Gary J. Lelli, Jr.Mount Sinai School of Medicine

Jamesetta H. LewisOhio University College of OsteopathicMedicine

Betty LimUniversity of Buffalo

Sung E. LoGerfoUniversity of Washington

Jennifer MainUniversity of Rochester

Michele MakYale University

Todd McCallUniversity of Washington

Robert N. McLayTulane University

Anastasia L. MisakianUniversity of California, San Diego

Steven H. MitchellUniversity of Washington

Jeffrey B. MuehlingUniversity of Washington

Delma J. NievesUniversity of Washington

Tanya L. PageMount Sinai School of Medicine

Sunil M. PatelUniversity of Pittsburgh

Monica T. PetersonSaint Louis University

34

Laura PhangUniversity of California, San Francisco

Ashutosh A. PradhanDuke University

Cynthia I. ResendezUniversity of California, San Francisco

Todd E. SchmidtIndiana University

Lauren K. SchwartzCornell University

Jeffrey R. ScottUniversity of Washington

Joanna B. SheinfeldYale University

Elliott SohnUniversity of Washington

Angela Y. SongUniversity of Pittsburgh

Rui SongCase Western Reserve University

Ellen E. SquireKansas University Medical Center

Craig StewartIndiana University

Calvin G. SyUniversity of Pittsburgh

Melba M. TaylorUniversity of Washington

Jo-Anne TeohSaint Louis University

Nghi K. TranUniversity of Michigan

Stephanie N. TurnageOhio State University

Jay UffordMount Sinai School of Medicine

Wendy D. WasdenUniversity of Alabama, Birmingham

Jonathan D. WeaverUniversity of California, Los Angeles

Melissa F. WellonsDuke University School of Medicine

Haoling Holly WengDuke University

Barton L. WiseBoston University

Terri L. WoodardUniversity of Pittsburgh

Jason YehUniversity of California, Los Angeles

1998 ScholarsYeran BaoUniversity of California, Los Angeles

Jeremy R. BariolaUniversity of Arkansas for Medical Sciences

Michael R. BibighausJohns Hopkins University

Doug BorgUniversity of Arkansas for Medical Sciences

Heather E. BrooksUniversity of Pittsburgh

Jeremy D. BuffordUniversity of Arkansas for Medical Sciences

Ian S. CaccamUniversity of Miami School of Medicine

Kerri L. CavanaughYale University

Roger S. ChanUniversity of California, San Diego

Peter J. ChaseSaint Louis University

Johnson Y. ChiuSaint Louis University

Sarah J. CraneSaint Louis University

Jessica CritchfieldUniversity of Washington

Joy E. CuezzeUniversity of Kansas Medical Center

Carrie A. CzarneckiSaint Louis University

Anne B. DavisUniversity of Alabama, Birmingham

Dustin L. DierksUniversity of South Dakota School of Medicine

Mark T. DillonUniversity of Michigan

Lisa M. FilionUniversity of Washington

LaTosha Y. FlowersUniversity of Arkansas for Medical Sciences

Tanya E. FroehlichYale University

Jennifer R. GarreauUniversity of California, Los Angeles

Jonathan B. GillUniversity of California, Los Angeles

Philip F. GogelSaint Louis University

John A. GuerrieroOhio University College of OsteopathicMedicine

Verna C. GuoNorthwestern University

Heidi J. HaapalaUniversity of Michigan

Randall K. HaradaUniversity of Pittsburgh

James C. HardyUniversity of Washington

Kevin M. HenderzahsIndiana University

Hilary M. HochbergCornell University Medical College

Emily E. HooiOhio State University

Evaleen F. HsiehUniversity of Miami School of Medicine

Chandra M. IveyCornell University Medical College

Randall E. JackUniversity of Nevada, Reno

Sherry L. JohnsonOhio University College of OsteopathicMedicine

Cornelia M. KacirOhio University College of OsteopathicMedicine

Jonathan KantorUniversity of Pennsylvania

Youjeong KimUniversity of Texas, Houston Medical School

Karen M. KnopsUniversity of California, Los Angeles

Negar G. KnowlesUniversity of Washington

E. Scott KopetzJohns Hopkins University

Elizabeth M. KwongUniversity of California, San Diego

Melinda J. LandchildUniversity of Washington

Anthereca E. LaneOhio State University

Janie M. LeonhardtNortheastern Ohio Universities College ofMedicine

Jimmy M. LiaoUniversity of Michigan

Tina M. LusignoloOhio State University

Lisa M. ManimalaUniversity of Rochester

Thomas A. ManningUniversity of Arkansas for Medical Sciences

Rotonya L. McCantsCornell University Medical College

Gina M. MerrittOhio University College of OsteopathicMedicine

Kathleen M. MitchellSaint Louis University

Smita NayakHackensack University Medical Center

Huy V. NguyenUniversity of Washington

Michael H. NguyenUniversity of California, Los Angeles

Cynthia Y. OhataUniversity of Washington

Mihwa C. PakChicago Medical School

Jonathon D. PalmerUniversity of Arkansas for Medical Sciences

Tahira A. PalmerUniversity of Alabama

Amie L. PetersonMedical College of Georgia

Anthony T. PhamUniversity of North Texas Health ScienceCenter

Basil PittengerUniversity of Washington

Catherine J. ReesWake Forest University

Brent RidgeUniversity of North Carolina at Chapel Hill

Matthew J. RobonOhio State University

Jennifer L. RupertUniversity of Washington

Sepehr B. SaniMedical College of Ohio

Elizabeth A. SchneiderUniversity of Arkansas for Medical Sciences

Melinda P. ShawEmory University

Grace L. ShihYale University

Jill Z. SimonCornell University Medical College

35

Sarah M. SnelgroveCornell University Medical College

Natalie P. SteeleUniversity of Washington

Michael E. SternCornell University Medical College

Michael M. TakamuraUniversity of California, San Diego

Sonja L. TalviUniversity of Chicago

William H. ThomSaint Louis University

Keith ThompsonUniversity of Arkansas for Medical Sciences

Nyree K ThorneState University of New York, Syracuse HealthScience Center

Mark C. TsaiUniversity of Pittsburgh

Lauren G. VarneyTufts University School of Medicine

Gina R. VaughnUniversity of Washington

Ariana J. VoraMount Sinai Medical Center

Vicki K. WallUniversity of Nevada, Reno

Thomas H. WatsonEmory University

Alyssa N. WengerUniversity of Arkansas for Medical Sciences

Beverly E. WhiteBaylor College of Medicine

Susan M. WomeldorfOregon Health Sciences University

Andrea WongUniversity of Medicine and Dentistry of NewJersey

Christine A. WuUniversity of California, Los Angeles

Zimu N. ZhengUniversity of California, San Diego

1997 ScholarsTanya BarauskasUniversity of California, Los Angeles

Julie BartikOhio University College of OsteopathicMedicine

Naveena BobbaUniversity of Pittsburgh

Deborah BoyleUniversity of Massachusetts

Karl BuekersOhio State University

Ian CaccamUniversity of Miami

Milan ChhedaAlbert Einstein College of Medicine

Kara CumminsSaint Louis University

Tracy DeAmicisJohns Hopkins University

David DeGuzmanUniversity of Michigan

Nancy DunbarUniversity of Connecticut Health Center

Arom EvansUniversity of Washington

Darlene GabeauYale University

David GanzHarvard Medical School

Colin GillespieFinch University of Health Sciences

Shannon GrosdidierUniversity of South Dakota

Colin HamblinUniversity of Rochester

James HekmanUniversity of Chicago

Aram HezelState University of New York, Buffalo

Rhadjena HilliardMount Sinai School of Medicine

Cheryl HoUniversity of California, San Diego

Kristin HumphreysThe Pennsylvania State University College ofMedicine

Joachim IxUniversity of Chicago Pritzker School ofMedicine

Jennifer JacksonUniversity of Pittsburgh School of Medicine

Jason KahnUniversity of Rochester

Kevin KerberUniversity of South Carolina School ofMedicine

Aaleya KoreishiUniversity of Michigan

Jacqueline KramerIndiana University

Sandhya KrishnanUniversity of Michigan

Alayne KulvickiUniversity of North Texas Health ScienceCenter

James LaiBowman Gray School of Medicine at WakeForest University

Dawn LazarusMount Sinai School of Medicine

David LiebermanStanford University

Ronnie LuBoston University

Kimberly MarkUniversity of South Dakota

Silbey MuiAlbert Einstein College of Medicine

Mark MuscoChicago Medical School

Shyam ParekhUniversity of Michigan

Andreea PartalCase Western Reserve University

Stephanie Peppler-SwopeSaint Louis University

Supriya RajpalUniversity of Michigan

Louis RamosUniversity of Rochester

Alvie C. RichardsonUniversity of Nevada, Reno, School of Medicine

John RogowskiUniversity of California, Los Angeles

Andrew RossMount Sinai School of Medicine

James RudolphLoyola University Chicago Stritch School ofMedicine

Tanya RuffOhio State University

Neha SangwanUniversity of Buffalo

Donna SassamanUniversity of Medicine and Dentistry of NewJersey

Mary SehlBrown University

Victoria SokoloveUniversity of Pennsylvania

Timothy TaMedical College of Wisconsin

William TewUniversity of Rochester

Blake WeathersbyUniversity of Alabama School of Medicine

Heather WhitsonCornell University

Cecilia WieslanderUniversity of California, Los Angeles

Jennifer WintersOhio University College of OsteopathicMedicine

David WuUniversity of Michigan

Carrie ZimmerUniversity of Michigan

1996 ScholarsMatthew AndersonUniversity of South Dakota

Alex AuseonOhio University College of Medicine

Todd BaileySaint Louis University

Gavin BaumgardnerOhio University College of Medicine

Christine BittnerOhio University College of Medicine

David BroumandiEmory University

Kathleen BurgessUniversity of Washington

Craig CalhounSaint Louis University

Scott CarlosUniversity of Michigan

Michael ChenUniversity of Michigan

Lillian ChiangUniversity of California, Los Angeles

36

Yu-Chi ChungUniversity of Texas Health Science Center atSan Antonio

Paul CunninghamUniversity of Washington

Dolon DasBaylor College of Medicine

Mohak DaveUniversity of South Carolina

Linda V. DeCherrieUniversity of Chicago

Michael FeloneySaint Louis University

Debbie FishkindMount Sinai School of Medicine

Suet-Ying FungCornell University

Poonam JhaUniversity of Michigan

Kenneth JungSaint Louis University

Meryem KokerUniversity of Michigan

Naveendra KoriviUniversity of North Texas

Susan KriegUniversity of Pittsburgh

Vidya KrishnanUniversity of Michigan

Dave LeeSaint Louis University

William LewUniversity of Michigan

Kristina LiaugaudasSaint Louis University

Moe LimHarvard Medical School

Kenneth LinCase Western Reserve University

Heather LiszkaUniversity of Pittsburgh

Karen LudlowNew York Medical College

David MandelMedical College of Ohio

Kimberly MarkUniversity of South Dakota

Jill MhyreUniversity of Michigan

Babak MokariOhio University College of OsteopathicMedicine

Laurie MullerSaint Louis University

Ryan O’ConnellNew York University

Ghadir OloumiMount Sinai School of Medicine

Vipul ParikhUniversity of Michigan

Luon PengOhio University College of OsteopathicMedicine

Hoang PhamUniversity of Pennsylvania

Louis RamosUniversity of Rochester

Alvie C. RichardsonUniversity of Nevada, Reno

Neha SangwanState University of New York, Buffalo

Christopher SkidmoreSaint Louis University School of Medicine

Hans StohrerUniversity of Rochester

Andrew SwordUniversity of Michigan

Manoj ThakkerMount Sinai School of Medicine

Jessica UlbrichUniversity of Michigan

Jason Van IttersumUniversity of Michigan

Seamus WalshOhio University College of Medicine

Crispin WebbUniversity of South Dakota

Carlos WeissUniversity of Michigan

Michael WidlanskyUniversity of Michigan

Timothy WillinghamMayo Clinic

Flora YaoLoma Linda University

1995 ScholarsJulie AbrahamsonJohns Hopkins University

Eugene AhnNew York University Medical Center

Angela AllenSaint Louis University

Rendell AshtonJohns Hopkins University

Neeraj BadjatiaEmory University

James BoydSaint Louis University

D. Allen BrantleyWake Forest University

Jan BrinkUniversity of California, Los Angeles

William BuxtonEmory University

Julie BynumJohns Hopkins University

Kimberly CarterBaylor College of Medicine

Annie ChenCornell University School of Medicine

Francis CoyleUniversity of Connecticut

Cynthia DechenesUniversity of Rochester

Sophie DengUniversity of Rochester

Cynthia DennisonSaint Louis University School of Medicine

Roni DevlinUniversity of Colorado

Elaine DiCostanzoMount Sinai School of Medicine

Vamil DivanState University of New York, Buffalo

Jesse EislerMount Sinai School of Medicine

Frederick FaustCase Western Reserve

Sara FischerUniversity of South Dakota

Tamara FongOhio State University College of Medicine

Anne GalbraithUniversity of Utah

Ruth GrauperaJohns Hopkins University

Jennifer GrotSaint Louis University

Lucy GuerraMount Sinai School of Medicine

Susan HallLoma Linda University

Sara HoweNew York Medical College

Jordan KarpUniversity of Pittsburgh

Pamela KirschnerHarvard University

Alayne Kulvicki MarklandUniversity of North Texas

George KunzUniversity of Michigan

Siavash KurdistaniHarvard University

Timothy KuwadaUniversity of Connecticut

Alpa LaheriJohns Hopkins University

Timothy LewisWayne State University

Hallie LightdaleMount Sinai Medical Center

Jerry LinHarvard Medical School

Elizabeth LindenbergerStanford University

Shaden MarzoukSaint Louis University

Maritess MauricioStanford University

Lisa McAllisterOhio University College of Medicine

R. Steven MeadowsWake Forest University School of Medicine

Ellen Marie MonganColumbia University

Anna MoniasMount Sinai School of Medicine

Brian MulhallSaint Louis University

Christopher NgUniversity of California, Los Angeles

Philip NivatpuminUniversity of California, Los Angeles

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Ghadir OloumiMount Sinai School of Medicine

Elizabeth RashleyUniversity of South Carolina

Katherine ShiueWashington University

Crystal SimpsonUniversity of Texas Health Science Center atSan Antonio

Nitin SooryaSaint Louis University

Jeanne ThompsonUniversity of Pittsburgh

Raymond ThorntonUniversity of Pittsburgh

Thao TruongHarvard University

Frances ValdesJohns Hopkins University

Brinda VoraJefferson Medical College

Neal WaechterUniversity of Michigan

Herschel WallenUniversity of Michigan

Kathleen WalshUniversity of Des Moines College ofOsteopathic Medicine

Katie WardSaint Louis University

Paul WiseJohns Hopkins University

Danielle WoodallState University of New York, Buffalo

Edward YianUniversity of Michigan

Marcia ZuckermanHarvard University

1994 ScholarsPreetinder BrarHarvard University

Julie BynumJohns Hopkins University

Kimberly CingleCase Western Reserve University

Judith CymermanUniversity of Southern California

Laura B. DunnUniversity of California, San Francisco

Thomas MurrayUniversity of Connecticut

Jeff OdietHarvard Medical School

Medda RauhutBaylor College of Medicine

Samantha SegalUniversity of Connecticut

Lydia ShajenkoUniversity of Connecticut

Jeffrey SuchniakBowman Gray School of Medicine at WakeForest University

Joyce TangStanford University

Susan ThomasTexas A&M University

Chris TsuneishiChicago Medical School

Cordelia UddohUniversity of Pennsylvania

Kimberly VescoUniversity of California, San Diego

Richard WongNew York University Medical Center

Rhonda YantissHarvard Medical School

2005 ScholarsJeremy BroadnaxCase Western Reserve University

Mita DeorasNortheastern Ohio Universities College ofMedicine

Paul GunnCase Western Reserve University

Maxwell HillUniversity of Cincinnati College of Medicine

Jessica HolmesCase Western Reserve University

Evan HoweCase Western Reserve University

Jesse EislerMount Sinai School of Medicine

William GarnerNew York Medical College

Ceri HaddaMount Sinai School of Medicine

Argye HillisJohns Hopkins University

Mwango KashokiJohns Hopkins University

Hai KenneyOhio University College of Medicine

Sally LeeUniversity of North Texas

Moshe LewisMount Sinai School of Medicine

Mehran MandegarUniversity of Rochester

R. Steven MeadowsWake Forest University

Marc MendesGeorge Washington University

Lisa MoranSaint Louis University

Christine MurphyUniversity of Minnesota

Christine HungCase Western Reserve University

Alexander LarsonOhio State University College of Medicine

Ovidiu MarinaCase Western Reserve University

Eric McLoneyOhio State University College of Medicine &Public Health

Leland MethenyCase Western Reserve University

Jeanie WangNortheastern Ohio Universities

Aimee WingCase Western Reserve University

AFAR-Ohio Affiliate Medical Students

AFAR/Hartford Gero-Physician-ScientistTraining Program

This fellowship program aimed to develop a cadre of physician-scientistsqualified to teach and do research in their fields of specialization as theyrelate to the treatment of the elderly, and to establish a knowledge baseto enhance medical student, resident and fellowship training in thesedisciplines. This program was active from 1992 to 1993.

38

2001 RecipientsBeth Tyler-McMahon, Ph.D.Mayo Clinic, JacksonvillePeptide Nucleic Acids Targeted to theAmyloid Precursor Protein

Yanming Wang, Ph.D.University of Pittsburgh Medical CenterAmyloid Probes in Aging and Alzheimer’sDisease: Dual Agents for Both PET andSPECT

AFAR/ISOA Program for Drug Discoveryin Cognitive Decline and Alzheimer’s Disease

One-to two-year awards provided support for innovative drug discoveryprojects by junior faculty (M.D.’s and Ph.D.’s) interested in a career in drug discovery in Alzheimer’s disease and related dementias. Sponsoredby the Institute for the Study of Aging. This program was active from 2000 to 2001.

2000 RecipientJack T. Rogers, Ph.D.Harvard Medical SchoolA New Translation Regulatory Target in theAlzheimer’s APP Transcript

2001 RecipientsDeborah A. Ferrington, Ph.D.University of MinnesotaProteomics of Modified Retinal Proteinswith Aging

Vassiliki Poulaki, M.D.Massachusetts Eye and Ear InfirmaryMechanisms of Neovascularizationin Age-Related Macular Degeneration

AFAR/The Foundation for Fighting BlindnessJoint Program for Career DevelopmentAwards in Support of Research on Age-Related Macular Degeneration

One-to two-year awards created for junior investigators to facilitateadvances in laboratory and clinical research, enhance the understanding ofthe etiology and pathogenesis of age-related macular degeneration, anddevelop innovative strategies to prevent, treat or cure this blinding disease.

1993 Fellows inGeriatric GynecologyLauren Nathan, M.D.University of California, Los Angeles

Carmen Sultana, M.D.University MacDonald Womens Hospital/Case Western Reserve University

M. Chrystie Timmons, M.D.Duke University Medical Center

1992 Fellows inAnesthesiologyG. Alec Rooke, M.D., Ph.D.University of Washington School of Medicine

Randall M. Schell, M.D.Duke University Medical Center

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AFAR Milestones

1981

n Irving S. Wright, M.D., gathers agingresearch leaders at the annual meeting ofthe American College of Physicians inNew Orleans and founds AFAR.

1982

n The first AFAR Research Grants are awarded.

n First Irving S. Wright Award given toNathan W. Shock, Ph.D.

1984

n First AFAR state affiliate formed inOhio.

1986

n Charles A. Dana AFAR TravelingScholars Program established to encour-age interest in geriatric medicine amongfuture physicians.

1987

n George E. Doty is elected Chair of theBoard of Directors.

n The Merck Company Foundation spon-sors new fellowships in geriatric clinical pharmacology.

1988

n AFAR holds first grantee conference,bringing scientists together to shareinformation, discuss research and createopportunities for future cooperation.

1991

n The John A. Hartford Foundation fundsnew Gero-Physician-Scientist TrainingProgram to provide physicians in variousspecialties an opportunity to pursue train-ing and research in geriatric medicine.

1993

n Hadley Ford is elected Chair of theBoard of Directors.

1994

n AFAR receives $14 million grant fromThe John A. Hartford Foundation, TheAtlantic Philanthropies and TheCommonwealth Fund to administer thePaul Beeson Physician Faculty Scholars inAging Research Program, the nation’slargest non-governmental award programin academic geriatrics and agingresearch.

n AFAR and The John A. HartfordFoundation collaborate to start theHartford/AFAR Medical Student GeriatricScholars Program.

n The Glenn Foundation for MedicalResearch funds new Glenn/AFAR StudentScholarship Program for Research in theBiology of Aging.

n Annual AFAR Research Grants top $1 million.

1996

n AFAR launches four-part media brief-ing series on older women’s health withsupport from the Bristol-Myers SquibbFoundation.

n AFAR develops a website,www.afar.org.

1997

n AFAR launches Dorothy Dillon EwesonLecture Series to educate medical specialists on advances in aging researchwithin their own fields.

n Diane Nixon names grant in memoryof her mother, Nan Allen Nixon.

n The John A. Hartford Foundation fundsAFAR to establish a Coordinating Centerfor the Hartford Foundation’s Centers ofExcellence Initiative.

n AFAR launches Lifelong, a newsletterfor older patients published in Geriatricsmagazine.

n The Merck Company Foundation andAFAR create the Merck/AFAR ResearchScholarships in Geriatric Pharmacology.

n First “Friends of AFAR” dinner is heldin New York City.

n AFAR goes global with the firstInternational Conference on BiomedicalAspects of Aging Research held in Venice,Italy.

n Sponsors of the Paul BeesonPhysician Faculty Scholars in AgingProgram commit additional $14 million tofund 31 new Scholars.

1998

n The John A. Hartford Foundation andAFAR create the Academic FellowshipProgram in Geriatric Medicine andGeriatric Psychiatry.

1999

n Pfizer Inc joins with AFAR to create thePfizer/AFAR Research Grant Program.

2000

n AFAR and the Institute for the Study ofAging create the AFAR/ISOA Program forDrug Discovery in Cognitive Decline andAlzheimer’s Disease.

n The Fan Fox and Leslie R. SamuelsFoundation adds support for local med-ical students through the AFAR/SamuelsFoundation Medical Student GeriatricScholars Program.

n AFAR launches Infoaging.org, a con-sumer information website.

n The Starr Foundation joins the team ofBeeson Program sponsors.

2001

n AFAR and the Glenn Foundation forMedical Research create awards programfor post-doctoral fellows.

n Foundation for Fighting Blindness andAFAR establish a joint program for careerdevelopment awards in support ofresearch on age-related macular degen-eration.

40

2002

n AFAR receives funding from the MerckCompany Foundation with a matchinggrant from the Glenn Foundation forMedical Research to co-fund a segmentof the Science of Aging KnowledgeEnvironment (SAGE-KE) project.

n The William Randolph HearstFoundation contributes to the AFARResearch Grant Program.

2003

n AFAR launches upstate affiliate pro-gram in Rochester, NY, funded by theStarr Foundation.

n The Ellison Medical Foundation andAFAR team up to support senior post-doc-toral fellows.

n AFAR and the Merck Institute on Agingand Health create HealthCompass.org.

2004

n Diana Jacobs Kalman elected Chair ofthe Board of Directors.

n AFAR launches southeast affiliate atEmory University in Atlanta, GA.

n AFAR celebrates the 10th anniversaryof the Beeson Program with the addedsupport of the National Institute on Agingand the new name of the Paul B. BeesonCareer Development Awards in AgingResearch.

n The Pfizer/AFAR Innovations in AgingResearch Award is created.

n The William Randolph HearstFoundation adds support to the MedicalStudent Geriatric Scholars Program.

n Terrapin Society created.

2005

n The Glenn Foundation and AFARcollaborate to create the Glenn/AFARBreakthroughs in Gerontology (BIG)Award.

n AFAR, The John A. Hartford Foundationand other foundations partner with theNIA on the Medical Student GeriatricProgram, renamed the Medical StudentSummer Research Training in AgingProgram. Foundations include TheWilliam Randolph Hearst Foundation, TheCleveland Foundation, Cardinal HealthFoundation, Lillian R. GleitsmanFoundation, Community HealthFoundation of Western & Central NewYork, The New York Community Trust andan anonymous donor.

n The Novartis Foundation joins withAFAR to establish the Aging WellInitiative.

2006

n The Julie Martin Mid-Career Award inAging Research is created by the EllisonMedical Foundation.

n The Fannie E. Rippel Foundation establishes the Fannie E. RippelFoundation/AFAR New InvestigatorAwards on Gender Differences inCardiovascular Disease in Older Adults.

The American Federation for Aging Research (AFAR) is a nonprofit organizationwhose mission is to support biomedical research on aging. We fulfill thismission by:

ä Supporting biomedical research that furthers our understanding of theaging process and its associated diseases and disorders;

ä Offering opportunities for scientists and physicians to exchange new ideasand knowledge about aging;

ä Building a cadre of early career scientists in aging research and in the practice of geriatric medicine; and

ä Promoting awareness among the general public about the importance ofaging research.

Since 1981, AFAR has awarded nearly $87 million to more than 2,100 early tomid-career investigators and students, with the goal of encouraging more ofthe nation’s scientists and physicians to enter and stay in the fields ofgerontology and geriatric medicine. These scientists are conducting cutting-edge research on aging and age-related diseases, such as Alzheimer’s, cancer,osteoporosis, diabetes and heart disease. Support for AFAR grants comes fromthe generous contributions of corporations, foundations and individuals. For more information about AFAR, please visit our organizational website,www.afar.org. For more information about aging research and staying healthyas you age, please visit our consumer websites, www.Infoaging.org andwww.HealthCompass.org.

Celebrating A Quarter Century

of Research

Letter from the Executive Director ............................1

2005 Selection Committees ....................................2

AFAR Research Grant ..............................................6

AFAR Affiliate Research Grant ................................16

AFAR/Glenn Breakthroughs in Gerontology (BIG) Award ....16

AFAR/Pfizer Innovations in Aging Research Award ............16

AFAR/Pfizer Research Grant ..............................................17

Paul Beeson Career Development Award in Aging Research ............................................................17

AFAR/Merck Junior Investigator Award in Geriatric Clinical Pharmacology........................................20

AFAR/Ellison Medical FoundationSenior Postdoctoral Fellows ............................................20

AFAR/Glenn Research Grant for Postdoctoral Fellows ........21

AFAR/Merck Research Scholarship in GeriatricPharmacology for Medical and Pharmacy Students ..........21

AFAR/Glenn Scholarship for Research in the Biology of Aging ....................................................22

AFAR/The John A. Hartford Foundation Academic FellowshipProgram in Geriatric Medicine and Geriatric Psychiatry ....27

Medical Student Summer Research Training in Aging Program ..............................................29

AFAR-Ohio Medical Student Summer Research Training inAging Program ................................................................37

AFAR/ISOA Program for Drug Discovery in Cognitive Declineand Alzheimer’s Disease ................................................38

AFAR/The Foundation for Fighting Blindness Joint Program for Career Development Awards in Support of Research onAge-Related Macular Degeneration ..................................38

AFAR/Hartford Gero-Physician-ScientistTraining Program ............................................................38

AFAR Milestones..............................................................39

Major Supporters of the 2005 Grant Programs

The AFAR Board of Directors

Anonymous Donor

The Atlantic Philanthropies

The Bedminster Fund

Cardinal Health Foundation

The Clarence and Anne Dillon Dunwalke Trust

The Cleveland Foundation

Community Health Foundation of Western & Central New York

Eisai Inc

The Ellison Medical Foundation

Lillian R. Gleitsman Foundation

The Glenn Foundation for Medical Research

The Partners of Goldman Sachs & Company

The John A. Hartford Foundation

William Randolph Hearst Foundation

Diana J. and C. A. Kalman

F. M. Kirby Foundation, Inc.

Merck Company Foundation

National Institute on Aging

The New York Community Trust

Diane Nixon

Pfizer Inc

The Richard and Hinda Rosenthal Foundation

Joseph L. K. Snyder Trust

The Starr Foundation

The Irving S. Wright Endowment

AFAR Grant Recipients — 1981-2005

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