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8/6/2019 AHA Intro Julie
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Welcometo
Autism: Hope in ActionA-HA Conference
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Autism: Hope in Action
When hope meets action,
children get better
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Setting the Stage
Julie Matthews
Certified Nutrition Consultant
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What is Autism and
Autism Spectrum Disorder (ASD)?
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Autism is caused by a
combination of
Genetic Predispositionand
Environmental Assaults
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Genetic Predisposition
Gene Sequence Gene Expression
Influenced by toxins and poor nutrition
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Nutrition and Gene Expression
Cooney CA, Dave AA, Wolff GL. Maternal Methyl Supplements in Mice Affect Epigenetic Variation and DNA
Methylation of Offspring. The American Society of Nutritional Sciences J Nutr. 132:2393S-2400S, 2002
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Environmental Assaults
Heavy metals Viruses and vaccines Plastics Environmental chemicals Pesticides
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Autism: Whole Body Disorder
Brain is Downstream
Yeast toxins
Undermethylatedneurotransmitters
Brain inflammation
Increased toxicity
Nutrient deficiencies
Opiates
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Biochemistry
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Effects of Faulty Biochemistry in Autism
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Bodys Effect on BrainAutism, ADHD and other Childhood Disorders
IMMUNE
Gut Inflammation
Poor pathogen fighting
Food sensitivities
DIGESTION
Leaky gut
Dysbiosis
Less nutrient absorption
DETOXIFICATION
Decreased detoxification
Food additives
NEUROLOGY
Brain Inflammation
Opiates
Microbial toxins
Neurotransmitters
Nutrient deficiencies
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Poor Immune Function
and Inflammation
Immune fights viruses, bacteria and yeast.Weak system will cause more susceptibility to
infection. Often more need for antibiotics.
Possible difficulty in handling vaccinations? Inflammation related disorders like allergies
and asthma have increased
Inflammation of the brain affectsautism
Decreased pathogenic fighting
Increased inflammation
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Poor Detoxification
Poor Detox - more reaction & damage from toxins Harder time processing artificial ingredients (known to
create hyperactivity/ADHD in even NT children)
More likely to be damaged by pesticides and heavymetals because of a reduced ability to detoxify them
(known neurotoxins)
Important to avoid toxins for
children with autism and ADHD
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Poor Digestion(Inability to digest & absorb necessary nutrients)
Nutrients such as calcium and magnesium areneeded for enzyme processes and brain function, as
well as growth and repair
Improper breakdown of proteins creates peptides(such as opiates to react to)
Inadequate amino acids forcreating neurotransmitters
for attention, cognition,
feelings of wellbeing
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Importance of GI Health
Gut has constant contact with food
Immune: Physical barrier of defense against bacteria, viruses, etc. Largest part of the immune system (70%) found in the gut
Neurotransmitters: The greatest amount (90%) of the brain chemical
serotonin is found in the GI tract
Amino acids (absorbed from protein digestion)are precursors for neurotransmitters
Full body function: Vitamins/minerals absorbed in the gut are cofactors for enzyme
reactions, metabolism, conversion of nutrients and fats
All disease begins in the gut- Hippocrates, the father of modern medicine
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Nutritional Imbalances Zinc deficiency, mineral deficiencies, folate and B12 deficiency
copper excess, and more
Food Sensitivities
Gluten & Casein Peptides, Standard Food Allergies, PhenolSensitivity, and others
Digestive Problems Constipation, Diarrhea, Colitis, Inflammatory Bowel Disease
Chronic Infections Yeast, Dysbiotic Bacteria, Viruses
Biochemical Imbalances Methylation, transsulfuration, sulfation
Metabolic Processes Blood sugar dysregulation, oxalate problems, hypothyroid
Imbalances in ASDs
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Immune imbalances Immune Deficiency Th1 & Th2 Imbalances Autoimmune reactions
Heavy Metal Toxicity Mercury, lead, arsenic
Neuroinflammation Glutamate sensitivity Microglial activation/hyper-reactivity
Neurotransmitter imbalances Serotonin, dopamine, acetylcholine imbalances
Genetics Methylation (MTHFR), SLOS, PON1, Hyperoxaluria
Imbalances in ASDs
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Sonya Doherty, ND
How biomedical intervention
supports health and healing of
children with autism