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Aim of the conference

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Aim of the conferenceJapan is in one of the countries where research on infertility treatmentis more advanced. For this reason Serono Symposia InternationalFoundation designed an educational event that will present somerelevant outcomes of basic research, will introduce advances inprocedure aimed to define individual infertility profile and will discuss,in a very interactive way, treatment protocols. Renowned Japanese andinternational expert will contribute in this meeting providing participantswith a unique opportunity to improve their knowledge and exchangeexperience

Learning objectivesParticipants of this meeting will:• be updated on some of the most relevant outcomes of basic research in infertility

• acquire advanced methodologies to screen individual infertilityprofile

• discuss infertility treatment optimization

Target audienceThis program is targeted to clinicians and scientists working on AssistedReproduction Techniques

AccreditationSerono Symposia International Foundation (www.seronosymposia.org)will submit this program “Individualized controlled ovarian stimulationand objective gametes and embryo selection” (Yokohama, Japan- 7December, 2011) for accreditation by the European Accreditation Councilfor Continuing Medical Education (EACCME) and the Japan Society ofObstetrics and Gynecology (JSOG).

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All Serono Symposia International Foundation programs are organized solely topromote the exchange and dissemination of scientific and medical information. Noforms of promotional activities are permitted. All the Serono SymposiaInternational Foundation programs are made possible thanks to the unrestrictedEducational grant received from: Centre d’Esclerosi Multiple de Catalunya, Valld'Hebron University Hospital, ComtecMed, Congrex Sweden, Congrex Switzerland,Cryo-Save, Datanalysis, Esaote, European Society of Endocrinology, Fundación IVI,ISFP International Society for Fertility Preservation, ISMH International Society ofMen’s Health, K.I.T.E., Merck Serono, Ministry of Health of the State of Israel,University of Catania.

Scientific organizerYasunori YoshimuraDepartment of Obstetrics and GynecologyKeio University School of MedicineTokyo, Japan

Scientific secretariatSerono Symposia International FoundationSalita di San Nicola da Tolentino 1/b00187 Rome, ItalyAssociate Project Manager: Chloé XilinasTel.: + 39 06 420413 505 - Fax: + 39 06 420413 677E-mail: [email protected] Symposia International Foundation is a Swiss Foundationwith headquarters in 14, rue du Rhône, 1204 Geneva, Switzerland

Organizing secretariatc/o MA Convention Consulting Inc.Dai 2 Izumi-shoji Bldg., 4-2-6 Kojimachi, Chiyoda-kuTokyo 102-0083 JAPANPhone: +81 3 5275 1259Fax: +81 3 5275 1192E-mail: [email protected]

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List offacultymembers

Hiroyuki Abe Yamagata UniversityYonezawa City, Japan

David AlbertiniDepartment of Molecular and Integrative PhysiologyUniversity of Kansas Medical CenterKansas City, Kansas, USA

Yoshimasa Asada Asada Ladies Nagoya Clinic Nagoya, Japan

Robert Fischer Fertility Centre HamburgHamburg, Germany

Aisaku FukudaIVF Osaka ClinicOsaka, Japan

Juan Antonio García-VelascoIVI MadridRey Juan Carlos UniversityMadrid, Spain

Minoru IraharaDepartment of Obstetrics and GynecologyUniversity of Tokushima Graduate School of MedicineTokushima, Japan

Osamu IshiharaDepartment of Obstetrics & GynaecologyFaculty of MedicineSaitama Medical University Saitama, Japan

Minoru KoLaboratory of GeneticsNational Institute on Aging, NIHBaltimore, Maryland, USA

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Henry LeeseDepartment of Biology Hull York Medical SchoolUniversity of YorkYork, UK

Nicholas Macklon Department of Obstetrics and GynecologyUniversity of Southampton Southampton, UK

Hideki Mizunuma Department of Obstetrics and GynecologyHirosaki University School of MedicineAomori, Japan

Emre SeliDepartment of Obstetrics, Gynecology, and Reproductive SciencesYale University School of MedicineNew Haven, Connecticut, USA

Nao SuzukiDepartment of Obstetrics and GynecologySt. Marianna University School of MedicineKanagawa, Japan

Yuji Taketani Department of Obstetrics and GynecologyUniversity of TokyoTokyo, Japan

Takumi TakeuchiReproduction CenterKiba Park ClinicTokyo, Japan

Atsushi TanakaDepartment of Obstetrics and GynecologySaint Mother HospitalFukuoka, Japan

Yasunori Yoshimura Department of Obstetrics and GynecologyKeio University School of MedicineTokyo, Japan

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07.50 Registration

08.20 SSIF welcomeR. Fischer, Germany

Session I Biomarkers of gametes and embryo quality:from basic research to practice

Chairpersons: H. Mizunuma, Japan; E. Seli, USA

08.30 Mitochondria and ooplasmic donationT. Takeuchi, Japan

08.50 The future is now: oocyte plasmic exchange for aged oocytesA. Tanaka, Japan

09.10 Metabolic biomarkers of preimplantation embryoH. Leese, UK

09.30 Preimplantation-specific genesM. Ko, USA

09.50 Discussion

10.10 Coffee break

Session II Screening methodologies in infertility treatment

Chairpersons: O. Ishihara, Japan; Y. Taketani, Japan

10.30 Ovarian response prediction: from patient’s history to geneticsN. Macklon, UK

11.00 Oocytes quality: reliable markers in clinical practiceD. Albertini, USA

11.30 Oocyte and embryo selection based on oxygen consumptionH. Abe, Japan

12.00 Embryo selection: from genetics to the omicsE. Seli, USA

12.30 Discussion

13.00 Lunch

Scientific programWednesday - December 7, 2011

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Session III Panel discussion on: tailoring the treatmentapproach to improve outcomes

Chairpersons: R. Fischer, Germany; M. Irahara, Japan

14.00 Poor response: strategies for managementA. Fukuda, Japan

14.20 Individualized ovarian stimulationJ.A. Garcia-Velasco, Spain

14.40 Personalizing ART procedure based on AMH in JapanY. Asada, Japan

15.00 Ovarian stimulation in cancer survivorsN. Suzuki, Japan

15.20 Discussion

15.45 Closing remarksY. Yoshimura, Japan

15.50 End of meeting and coffee

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VenuePACIFICO Yokohama1-1-1, Minato Mirai,Nishi-ku, Yokohama, 220 - 00121, Japan

LanguageThe official language of this course will be EnglishSimultaneous translation Japanese from/to English will be provided

Registration feeThe symposium registration fee is JPY 10.000,00This fee includes:• All sessions• Symposium coffee breaks and lunches• Symposium materials• Certificate of attendance

Registration informationPlease visit the The Japan Society for Reproductive Medicine (JSRM)website for further information regarding the Serono SymposiaInternational Foundation Pre-Congress and the JSRM Congress:http://www.jsrm.or.jp/jsrm56/The website will be available by April 2011Registration to the Serono Symposia International FoundationPre-Congress will be open on December 6 from 18.00 to 20.00and December 7 from 7.50 to 8.20 at the PACIFICO Yokohama

Registration form and contactThe registration form is avalable online:https://mice.jtbgmt.com/SSIF2011/Or contact directly:JTB Global Marketing & Travel Inc. Convention Center,2-3-11 Higashi-Shinagawa, Shinagawa-ku, Tokyo 140-8604 JapanFax: +81-3-5495-0685Phone: +81-3-5796-5445E-mail: [email protected] note that the deadline to submit your registration is:November 4, 2011

Generalinformation

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LocationAround the time of the Black Ships, Yokohama was home to barely 600people. A century-and-a-half later, it’s Japan’s second metropolis, witha breezy atmosphere, fine food, parks and historic districts, and loadsof shopping. Unlike most Japanese cities, it’s also a city of distinctneighbourhoods, including Chinatown, the historic Motomachi andYamate districts, and the new seaside development of Minato Mirai 21.Yokohama is barely 20 minutes from central Tokyo, meaning that it’san easy day trip or nighttime excursion. Among Japanese it’s a populardate spot.

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