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Name: Mourushi RahmanID: 13102479Program: BBA

Topic

SIR ALEXANDER FLEMING

SIR ALEXANDER FLEMING WAS BORN ON AUGUST 6,1881,IN A FARM NEAR DARVEL,IN AYRSHIRE.

Birth

Childhood

He was the third of the four children of farmer Hugh Fleming(1816-1888)from his second marriage to Grace Stirling Morton(1848-19280),the daughter of a neighboring farmer.Hug Fleming had four surviving children from his first marriage.he was 59 at the time of his second marriage.

His family called him little alec. Because he was very small for his age When Alexander was 7 his father died so now as father died the family had now less money to live with.

Education

Alec started school when he was ten and he went to a primary school called Loudoun Moor in Darvel, Ayrshire.

In 1893 Alec starts school at Kilmarnock Academy in Ayrshire at the age of twelve.

When he was fourteen He left the Kilmarnock academy and went to London. He then attends Regent Street Polytechnic school in London for two years

In 1901 Alexander

Fleming enrolls in St Mary Mery Medical school

in London.

WorkFor eight years he worked in wright laboratory to find a

means to aid the the leucocytes in their fight against invading

bacteria

WorkIn 1914 sir Alexander joined R.A.M.C.The Royal Army Medical Corps (RAMC) is a specialist corps in the British Army which provides medical services to all British Army personnel and their families in war and in peace.

The pub opposite Fleming's laboratory that claims to have provided the source of the spores.

Work Place

Discovery of lysozymes

In 1922,sir Alexander had a cold when he was working with Petri dishes with bacteria on them. He accidentally sneezed on one of the dishes and it was sprayed with mucus. He was going to remove it, but he was curious to see what would happen. So he left the mucus on the dish and he later examined it. Alec discovered the mucus had dissolved the bacteria and killed it. Sir Alexander tried the same experiment with tears. He studied the human and animal samples and all the samples had the bacteria-killing substance. He called the substance a lysozyme.

Antibiotics

Modern antibiotics are tested using a method similar to Fleming's discovery.

Fleming's accidental discovery and isolation of penicillin in September 1928 marks the start of modern antibiotics . Before that, several scientists had published or pointed out that mould or penicillium sp. were able to inhibit bacterial growth, and even to cure bacterial infections in animals. Ernest Duchesne in 1897 in his thesis "Contribution to the study of vital competition in micro-organisms: antagonism between moulds and microbes", or also Clodomiro Picado Twight whose work at Institut Pasteur in 1923 on the inhibiting action of fungi of the "Penicillin sp" genre in the growth of staphylococci drew little interest from the direction of the Institut at the time. Fleming was the first to push these studies further by isolating the penicillin, and by being motivated enough to promote his discovery at a larger scale.

Germ Paintings created by Sir Alexander Fleming

Fleming was a member of Chelsea Arts Club and produced many germ paintings using different pigmented bacteria.

Fleming’s painting made of microbes

Fleming personality

Fleming was a shy man Flaming also was Lackluster lecture who was

described by one student as a shocking lecturer the worsted you could possibly imagine

Nevertheless Fleming inspired many by his future work

Personal Life

Personal life: he married Dr. Amalia Voureka, a Greek bacteriologist in 1952. Their only child, Robert Fleming, (b. 1924 died 2 July 2015) became a general medical practitioner; Robert married Kathleen a trained radiographer on 10 September 1955 and had two children Andrew (b. 1956) and Sarah (b. 1959)

Awards and recognition..

Memberships in 87 Scientific Academies and Societies The Nobel Prize with Howard Florey and Ernst B. Chain for Physiology or Medicine in 1945.

Collected 25 Honorary Degrees 26 Medals 18 Prizes 13 statues

Fleming and Florey were knighted in 1944

Death..

He dies of a heart attack in London on March the 11th 1955. He was 73 years, 7 months and 5 days old when he died .

Myths

The popular story of Winston Churchill's father paying for Fleming's education after Fleming's father saved young Winston from death is false. According to the biography, Penicillin Man: Alexander Fleming and the Antibiotic Revolution by Kevin Brown, Alexander Fleming, in a letter to his friend and colleague Andre Gratia,

described this as "A wondrous fable." Nor did he save Winston Churchill himself during World War II. was saved by Lord Moran, using sulphonamides, since he had no experience with penicillin, when Churchill fell ill in Carthage in Tunisia in 1943.

Bibliography

https://en.wikipedia.org/wiki/Alexander_Fleming#E

http://www.nobelprize.org/nobel_prizes/medicine/laureates/1945/fleming-bio.htmlarly_life_and_education

http://www.biography.com/people/alexander-fleming-9296894

Thank you