of 14
2. What is Alzheimers?Alzheimers is a diseaseWhen you get Alzheimers Some changes would be:that attacks the brain nerve you start to have someknowledge, speaking, andcell. changes.behavior. People who mostly get thisAlzheimers is the 6th causesdisease are people fromto death. ages 65 and older. 3. HistoryWhen: They found the disease in 1906.Who: The founder is Dr. Alois Alzheimer. He is aGerman Physician.How: A woman of 51 years of age suffered from a strangebrain disorder. She had symptoms like: Memory lost,language problems, and behavior changes. 4. How Mutation Causes AlzheimersDisease APP: Provides instructions Alzheimers is caused byfor making a protein calledgene mutations that can be There are three which are amyloid precursor.passed to you from one of APP, PSEN1,& PSEN2.your parents.PSEN1: makes protein forPresenilin 1 *APOE (Apolipoprtein E): ItPSEN2: makes a protein works with lipids in thecalled Presenilin 2.body to make molecules. 5. Symptoms There are ten symptoms which are:1.Memory loss2.Problems with language3.Disorientation of time and place4.Misplacing things5.Problems with abstract thinking6.Changing in mood and behavior7.Changes in personality8.Loss of initiative9.Poor or decreased judgment10. Difficulties performing familiar tasks 6. Women areRisk Factors affected more because they they live longer thenRisk Factor : Agemen. It affects 10% of the It affects 35% of thepopulation over the age population over the age of 65.of 85. 7. Risk FactorsRisk Factor: Family HistoryIf you have someone related to When it runs in the familyyou and they have AlzheimersGenetically or environmental ityou are most likely to get it.plays a role. The chances of you gettingAlzheimers increases if more than one family member has it. 8. GeneticallyRisk Genes: it increases the possibility of getting a disease, but dont hope that itwill come.Deterministic Genes: directly causes thedisease and anyone who inherits it will get the disease. Scientist have been identifying many risk genes implicated in Alzheimers disease. This is called Familiar AlzheimersDisease. Many family members in manygenerations are affected. The Earliest you Everyone gets APOE from both parents.can get it is at age 30-40. Those who get APOE-e4 from one parenthave chances of getting Alzheimers. if youget it from both you have higher risks. 9. ComplexAge, family, andGenetically risk factorsWe may get thesefactors from well, lifestyle, and effectiveInteraction can never be changed.management.This can cause youHead Head injury and Alzheimers are veryAlzheimers especially when Trauma occur Traumalinked together.repeatedly and involvesloss of consciousness.It leads to brain health A heartbeat pumps 20-Heart-Head and heart health. Thebrain is linked by one25% of your blood toyour head. When you of the bodys richest get Alzheimers it mayConnection networks of bloodvessels.damage the heart andblood vessels. 10. ContinuationGeneral Healthy aging mightTry to have goodweight. Avoid alcohol,Healthyhelp keep your brain aswell as your body fit. stay socially connected, and exercise your brainAging and body. 11. How To Help: Alzheimers Walk This organization hasThis walk bringsIt used to be calledraised more than together families, Memory Walk in $300 million forfriends, and 1989.research, education, caregivers. and programs. 12. Relation1. The gene has something to do in which you getor dont get Alzheimers. You get the genes fromyour parents.2. The nervous system is part on whichAlzheimers Disease makes the bodycommunication stop. The brain sends messagesback and forth to the body. 13. "Alzheimers Association National Office." Alzheimers Association National Office.Web. 14 Nov. 11. . "Alzheimers Association - Walk." Alzheimers Association - Walk. Web. 09 May 2012.. "Alzheimers Disease Fact Sheet." National Institute on Aging. Web. 09 May 2012.. "Alzheimers Foundation of America." Alzheimers Foundation of America. Web. 09 May2012. . "APOE." - Apolipoprotein E. Web. 24 May 2012. . "The Facts on Alzheimers Disease." The Facts on Alzheimers Disease. Web. 09 May2012. .
