Amlodipine

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standards@synzeal.com www.synzeal.com

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SZ-A005001

Amlodipine Maleate

88150-47-4

C20H25ClN2O5 C4H4O4

408.88 116.07

SZ-A005002

Amlodipine EP impurity A

88150-62-3

C28H27ClN2O7

538.99

SZ-A005003

Amlodipine EP impurity B

721958-72-1

C29H32ClN3O7

570.05

SZ-A005004

Amlodipine EP Impurity C

721958-74-3

C22H30ClN3O6

467.95

SZ-A005005

Amlodipine EP Impurity D

113994-41-5

C20H23ClN2O5

406.86

SZ-A005006

Amlodipine EP Impurity E

140171-65-9

C21H27ClN2O5

422.9

SZ-A005007

Amlodipine EP Impurity F

140171-66-0

C19H23ClN2O5

394.9

SZ-A005008

Amlodipine EP impurity G

43067-01-2

C17H18ClNO4

335.79

SZ-A005009

Amlodipine EP Impurity H

318465-73-5

C28H29ClN2O8

557.00

SZ-A005010

Amlodipine Azido Impurity

88150-46-3

C20H23ClN4O5

434.8

SZ-A005011

Amlodipine 4-Chloro Analogue

90445-02-6

C20H25ClN2O5

408.9

SZ-A005012

Amlodipine Related Compound K

1621516-91-3

C18H20ClNO3

333.8

SZ-A005013

R-Amlodipine

103129-81-3

C20H25ClN2O5

408.89

SZ-A005014

S-Amlodipine

103129-82-4

C20H25ClN2O5

408.89

SZ-A005015

N-Fomyl Amlodipine

93848-81-8

C21H25ClN2O6

436.9

SZ-A005016

Amlodipine Impurity

103094-30-0

C25H34ClNO6

480.01

SZ-A005017

Amlodipine Metabolite 5

114018-75-6

C19H18ClNO7

407.81

SZ-A005018

Amlodipine N-Lactoside

N/A

C32H45ClN2O15

733.17

SZ-A005019

Amlodipine Metabolite

113994-45-9

C20H20ClNO7

421.84

SZ-A005020

Amlodipine Impurity ( N-(2-hydroxyethyl)-phthalamic acid )

58509-24-3

C10H11NO4

209.2

SZ-A005021

Amlodipine Related Compound (Z-Isomer) (Ethyl 2-(2-Chloro-benzylidene)-4-[2-(1,3-dioxo-1,3-Dihydro-Isoindol-2-yl)-Ethoxy

N/A

C23H20ClNO6

441.87

SZ-A005022

Amlodipine Di-Phthalimide Impurity

223734-98-3

C37H32ClN3O8

682.14

SZ-A005023

Amlodipine Aspartic Acid Impurity

400602-35-9

C24H29ClN2O9

524.96

SZ-A005024

Amlodipine Impurity 6

3891-07-4

C10H9NO3

191.19

SZ-A005025

Amlodipine Impurity 7

N/A

C19H23ClN2O5

394.86

SZ-A005026

Amlodipine Impurity 8

110962-94-2

C19H18Cl2N2O4

409.27

SZ-A005027

Amlodipine Impurity 9

496024-43-2

C20H22ClNO5

391.85

SZ-A005028

Amlodipine Impurity 9

90445-05-9

C14H22N2O5

298.34

SZ-A005029

Amlodipine Impurity 10

2170104-51-3

C19H22ClNO5

379.84

SZ-A005030

Amlodipine Impurity 11

N/A

C12H20N2O3

240.3

SZ-A005031

Amlodipine N-Glucose

N/A

C26H35ClN2O10

571.03

SZ-A005032

Amlodipine Related Compound (E-Isomer) (Ethyl 2-(2-Chloro-benzylidene)-4-[2-(1,3-dioxo-1,3-Dihydro-Isoindol-2-yl)-Ethoxy

400024-08-0

C23H20ClNO6

441.87

SZ-A005033

Atorvastatin Amlodipine Dimer

N/A

C53H58ClFN4O9

949.53

SZ-A005034

Amlodipine Impurity 12

N/A

C23H22ClNO7

459.89

SZ-A005036

Amlodipine Impurity 14

113994-37-9

C19H23ClN2O5

394.86

SZ-A005037

Amlodipine Impurity 15

1809326-44-0

C18H21ClN2O5

380.83

SZ-A005038

Amlodipine Impurity 16

N/A

C20H23ClN2O7

438.87

SZ-A005039

Amlodipine Impurity 17

N/A

C20H24ClNO6

409.87

SZ-A005040

Amlodipine Impurity 18

1821498-25-2

C17H19ClN2O5

366.80

SZ-A005041

Amlodipine Impurity 19

N/A

C26H29ClN2O7S

549.05

SZ-A005042

Amlodipine Impurity 20

70677-78-0

C17H19NO4

301.3

SZ-A005043

Amlodipine Besylate

111470-99-6

C20H25ClN2O5.C6H6O3S

567.07

SZ-A005044

Amlodipine Ethyl Besylate

515-46-8

C8H10O3S

186.2

SZ-A005045

Amlodipine Mannitol Adduct

N/A

C26H37ClN2O10

573.0

SZ-A005046

Amlodipine Impurity 21

79781-21-8

C18H20ClNO5

365.8

SZ-A005047

Amlodipine Impurity 22

93848-82-9

C22H27ClN2O6

450.9

SZ-A005048

Amlodipine Methyl Ester

N/A

C25H31ClN2O9

539.0

SZ-A005049

88150-75-8

C16H17NO6

319.31

SZ-A005050

88150-52-1

C20H26N2O5

374.44

SZ-A005051

Amlodipine Impurity 24

34148-67-9

C19H22ClNO4

363.84

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Deschloro AmlodipineAmlodipine Impurity 23

Amlodipine was first patented in 1986 with commercial sale beginning in 1990. Amlodipine is a long-acting 1,4-dihydropyridine c a l c i u m c h a n n e l b l o c k e r. I t a c t s p r i m a r i l y o n v a s c u l a r s m o o t h m u s c l e c e l l s b y s t a b i l i z i n g voltage-gated L-type calcium channels in their inactive conformation.Amlodipine, sold under the brand name Norvasc among others,is a medication used to treat high blood pressure and coronary artery disease. A second proposed mechanism for the drug’s vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth muscle carbonic anhydrase. Some studies have shown that amlodipine also exerts inhibitory effects on voltage-gated N-type calcium channels. N-type calcium channels located in the central nervous system may be involved in nociceptive signaling and pain sensation. Amlodipine is used to treat hypertension and chronic stable angina.

SynZeal Research offers all related impurities which certified COA with all characterization data like IR, Mass, HPLC Amlodipine purity,NMR & TGA report. We also provide CMR, DEPT and detailed structurecharacterization report as perrequirements.

related products are being used by major pharmaceutical companies across the globe for their ANDA/DMF filing.Amlodipine