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Proceedings of the Ninth Annual Conference of the IEEE Engineering in Medicine and Biology Society The Boston Park Plaza Hotel, Boston, MA November 13-16, 1987 UNiVERSITATSOiBUOTHEK HANiMCWER TECHN1.SCHE , JNF0RMATIOi.;3ciiBIJOTHEKj 87CH2513-0 Volume 2 of 4
Transcript

Proceedings of the

Ninth Annual Conference of the

IEEE Engineering in Medicine and

Biology Society

The Boston Park Plaza Hotel, Boston, MA

November 13-16, 1987

UNiVERSITATSOiBUOTHEKHANiMCWER

TECHN1.SCHE,

JNF0RMATIOi.;3ciiBIJOTHEKj

87CH2513-0

Volume 2 of 4

Saturday, November 14 - Morning

Saturday, November 14 - Morning

ANESTHESIOLOGY

Anesthetic Systems

9:45-11:15 AMSession Chair: G. Rau

222.1 Man-Machine Communication for Monitoring, 427

Recording and Decision Support In an Anes¬

thesia Information System (AIS)Guenter Rau, Helmholtz-lnst. for Biomedical En¬

gineering, Aachen, West Germany

222.2 A New Recognizing Method of Epidural Space 429

for Epidural Anesthesia

S.-T. Young, National Yang-Ming Medical College,Taipei, Taiwan; C.-F. Chen, K.-H. Chen

222.3 A Large-Scale Multiple Model for Simulation 431

Study of Anesthesia

Robert Q.Y. Tham, Univ. of Wisconsin, Madison,Wl USA; V.C. Rldeout, F.J. Sasse

222.4 A Closed Loop Controller for End-Tidal Anes- 433

thetlc Concentration

Patrick J. Loughtln, Univ. of Utah, Salt Lake City,UTUSA; D.R. Westenskow

234.5 Theoretical Models and Experimental Studies 435

of Pulse OximetryDavid P. Brown, Univ. of Washington, Seattle, WAUSA; P.W. Cheung, M.A. Kenny, R.B. Shoene,K.P. Strohl, M.J.Decker

BIOELECTROMAGNETICS

Endogenous and Applied Fields in

Cartilage and Bone

8-9:30 AM

Session Chair: A. Grodzinsky, S. Elsenberg200.1 Electromechanical Potentials from Cortical 438

Bone

Richard A. Salzstein, Univ. of Pennsylvania,Philadelphia, PA USA; S.R, Pollack

200.2 Streaming Potential Measurements on Chemi¬

cally Modified BoneWendell S. Williams, Materials Research Lab., Ur-

bana, IL USA

200.3 Functional Significance of Bone Architecture: 440

The Regulation of Morphology by Electric

Fields

Clinton T. Rubin, SUNYMusculoskeletal Research

Lab., Stony Brook, NY USA; K.R. McLeod

200.4 Electrostatic and Physlcochomlcal Modulation 442

of Biosynthesis In CartilageMartha L. Gray, Massachusetts Inst, of Technol¬

ogy, Cambridge, MA USA

200.5 Mlcrocontlnuum and Macrocontlnuum Models 444

of Cartilage Electromechanical Theory and Ex¬

perimentEliot H. Frank, Massachusetts Inst, of Technology,Cambridge, MA USA; S.R. Elsenberg, A.J. Grod¬

zinsky

Progress In UnderstandingMicrowave Interactions with Tissue

9:45 -11:15 AMSession Chair: O. Gandhi

223.1 Electrical and Mechanical Forces on*

Membranes

Frank S. Barnes, Univ. of Colorado, Boulder, COUSA; H. Wachtel, R. Mlhran

223.2 The Effects of Microwave Exposure on the Im- *

mune SystemC.A. Cain, Univ. ofIllinois, Uibana, IL USA

223.3 Millimeter Wave Effects of Natural and Model 446

Cellular and Subcellular SystemsShirley M. Motzkin, Polytechnic Univ., Brooklyn, NYUSA

223.4 Thermal Comfort In the Microwave Environment 448

Eleanor R. Adair, John B. Pierce Foundation Lab.,New Haven, CTUSA

223.5 Impact of Advances In Bloelectromagnetlcs on 450

Standard-SettingMaria A. Stuchly, Bureau of Radiation and Medical

Devices, Health & Welfare Canada, Ottawa, ONCanada

xxxiv IEEE/Ninth Annual Conference of the

Engineering in Medicine and Biology Society

Saturday, November 14 - Morning

BIOLOGICAL APPLICATIONS

Morphimetrics: New Applications

8-9:30 AMSession Chair: W.C. Lambert

201.1 Sensitivity and Speciflefty of Diagnostic 452

Criteria: New Mathematical and Statistical Ap¬plications to Classical Morphimetrics.W. Clark Lambert, UMDNJ- New Jersey MedicalSchool, Newark, NJ USA

201.2 Applications of Morphimetrics to Nevocellular *

Nevl and Melanoma

Arthur R, Rhodes, Children's Hosp., Boston, MAUSA

201.3 Applications of Morphimetrics to Cell Sorter 454

Technology: Studies of Cell Viability and DNARepairWarren Tanz, UMDNJ- Graduate School of

Biomedical Science, Newark, NJ USA; W.C. Lam¬bert

201.4 Application of Morphimetrics to Studies of DNA 456

RepairW. Clark Lambert, UMDNJ - New Jersey MedicalSchool, Newark, NJ USA

201.5 Studies of Nuclear Proteins In DNA Repair 458

Muriel W. Lambert, UMDNJ- New Jersey MedicalSchool, Newark, NJ USA

BIOLOGICAL SIGNAL

ANALYSIS

Biological Signal AnalysisSymposium

9:45-11:15 AM

Session Chair: H. Ffshman

224.1 Rapid Acquisition and Analysis of Driving-Point 460

Functions In Nerve Membranes

Harvey M. Fishman, Univ. of Texas Medical

Branch, Galveston, TXUSA; W.C. Law, Jr.

224.2 Parallel Pathways for Information Flow from *

Retina to Brain

Robert Shapley, New York, NY USA

224.3 Dynamics of Bloelectrode Interfaces: Classical 462

Methods and Fractal AnalysisBanu Onaral, Drexel Univ., Philadelphia, PA USA;Y.Y. Tsao, M. Moussavi, H.H. Sun

*- manusorlpt

not received

IEEE/Ninth Annual Conference of the

Engineering in Medicine and Biology Society

XXXV

Saturday, November 14 - Morning

BIOMECHANICS

Biomechanics and Rehabilitation I

8-9:30 AMSession Chair: S. Mansouri

210.1 Accelerometer Assessment of Hyper-Reflexla 465

In Patellar Tendon Reflex

Larry W. Lamoreux, Shriners Hospital for CrippledChildren, San Francisco, CA USA; M.K. YoshkJa

210.2 Biomechanics and Rehabilitation *

Robert W. Mann, Massachusetts Inst, of Technol¬

ogy, Cambridge, MA USA

210.3 Rehabilitation Following Pressure Instrumented 467

Hip ArthroplastyW. Andrew Hodge, Massachusetts Inst, of Technol¬

ogy, Boston, MA USA; K.L. Carlson, R.S. Fijan,R.G. Burgess, P.O. Riley, W.H. Harris, R.W. Mann

210.4 The Propagation of Kinematic Disturbances In 469

Gait Models

Zvl Ladin, Boston Univ., Boston, MA USA; W.

Flowers

210.5 Human Wrist Ligament Biomechanics 471

Samuel E. Logan, Washington Univ., St. Louis, MOUSA; M.D. Nowak

210.6 Blomechanlcal Measurements for Diagnosis 473

and Assessment of DysphagiaNarender P. Reddy, Univ. ofAkron, Akron, OH

USA; M. Rane, B.R. Costarella, E. Canilang, J.

Costerllne

Biomechanics and Rehabilitation II

9:45-11:15 AM

Session Chair: E. Marsolals

226.1 Functional Neuromuscular Electrical Stlmula- 475tion of the Paraplegic Lower Extremities

E.B. Marso|ai3, VA Medical Center, Cleveland, OH

USA

226.2 Quantitative Assessment of Center of Pressure *

While Undertaking a Reach Task from a Wheel¬

chair

Martin W. Ferguson-Pell, Helen Hayes Hosp.,West Haverstraw, NY USA; B. Abreu

226.3 Computation of Functional Capacity: Strategy 477

and Example for Shoulder

George V, Kondraske, Univ. of Texas at Arlington,Arlington, TX USA

226.4 Motor Assessment for Prediction of Com- 479

munlcatlon Rate with Scanning Devices

Michael J, Rosen, Massachusetts Inst, of Technol¬

ogy, Cambridge, MA USA; C. Goodenough-Trepagnier, K.K. Chen, L. Jandura

226.5 Passive Knee Motion Test Apparatus 481

Robert C. Weber, Marquette Univ., Milwaukee, Wl

USA; G.F, Harris, D.V. Matesl, B. Chang

226.6 Tendon Transfers In Tetraplegia Controlled by 483FNS

Michael W. Keith, Case Western Reserve Univ.,Cleveland, OH USA; P.H. Peckham, K. Kllgore

BIOSENSORS

Neural Sensors

9:45-11:15 AMSession Chair: A.R. Zapata-Ferrer

212.1 A Printed Implantable Electrode for RecordingNeural Signals In Awake Animals

Y. Yonezawa, Hiroshima Inst, of Technology,Hiroshima, Japan; I. Ninomiya, N. Nishiura

212.2 Microelectronic Implants for Neural Bidirection¬

al InterfacingKamil Victor Ettinger, Univ. ofAberdeen, Aber¬

deen, UK; Z.M. Aharned, J. Brondo

212.3 Evaluation of Thin Film Encapsulants for

Blotransducers

David J, Edell, Massachusetts Inst, of Technology,Cambridge, MA USA

212.4 Electrode Spacing Considerations for Neural

Signal TransducersLloyd D. Clark, Jr., Massachusetts Inst, of Technol¬

ogy, Cambridge, MA USA; D.J. Edell

212.5 Electronic System for Behavioral Research

Angel R. Zapata-Ferrer, Inst. Mexlcano de Psl-

qulatria, Tlalpan, Mexico; C. Moncada-JImenez,M.A. Aguillon-Pantaleon

XXXVi IEEE/Ninth Annual Conference of the

Engineering in Medicine and Biology Society

Saturday, November 14 - Morning

CARDIOLOGY

ECG and EchocardiographyAnalysis

8-9:30 AMSession Chair: N.P. Reddy

202.1 An Off Line Computerized System for Two 494

Dimensional Echocardiography Image Process¬

ingGuy Lorette, Univ. Paris Val-de-Mame, Creteil,France; E. Petit, A. Corenthin, M. Gaudaire, P,

Bunel, J.M. Fillatre, T. Besnard

202.2 An Application of Fast Walsh Transform In ECG 497

DiagnosisB.N. Hung, Chung Yuan Christian Univ., Chungli,Taiwan; H.F. Cheng, Y.S. Tsai

202.3 On Shape Description of Vectorcardiograms 499

B.R. Shankara Reddy, Drexel Univ., Philadelphia,PA USA; I.S.N. Murthy

202.4 The Modelling of the ECG Signal Using Cubic 501

Spline InterpolationEwaryst Tkacz, Technical Univ. of Silesia, Qliwlce,Poland

202.5 Real-Time QRS-Complex Detection with Adap- 503

tlve Adjusting TechniquesSong-Kai Zhou, Shanghai Jiao Tong Univ., China;J.-T.,J.-R,Xu

202.6 A Microprocessor-Controlled Echocar- 505

dlographlc Tracking and Measuring SystemErxin Zheng, Chongqing Medical Univ., Chongqing,China; Y. Xu, C.L. Peng, D.W. Li, L.X. Ying

Forward Problem In

Electrocardiography

8-9:30 AM

Session Chair: R. Gulrajanl203.1 A Fine Grid Forward Simulation of the Total 507

Body Surface Electrocardiogram — Its Role In

the Development of Quantitative DiagnosticCriteria

Ronald H. Selvester, Univ. ofSouthern California,

Downey, CA USA; J.C. Solomon, G.D. Tolan

203.2 Forward Problem of Electrocardiography and 509

Magnetocardlography: A Continuing ChallengeB. Milan Horacek, Dalhousie Univ., Halifax, NS

Canada

203.3 Computer Modelling of Electrocardiograms and 511

Heart-Pacemaker Interface

Marek Malik, Charles Univ., Prague, Czechos¬

lovakia

Poster Session: Cardiology

8 AM - NOON

211. The Influence of Electrode Montage on Dlpole 513

Localization

K. Jeffrey Eriksen, Childrens Hospital ofLos An¬

geles, Los Angeles, CA USA

211. In Vivo Quantitative Assessment of Red Blood 515

Cells Transit In Microcirculations

Theodore Herrmann, Service Central de Medecine

Nucleaire, Saint-Etienne, France; A. Champailler,E. Gremillet, J. Juge, J. Healy

211. Automated Lldocalne Infusion for Closed-Loop 517

Control of Ventricular ArrhythmiaThomas C. Jannett, Univ. of Alabama at Birmin¬

gham, Birmingham, AL USA; L.C. Sheppard, G.N,

Kay

211. The Development and Animal Experiments of 519

Plasma Transplanting Device

Zhenyu Ji, Shanghai Univ. ofScience & Technol¬

ogy, Shanghai, China; B.Y. Chen, G.D. Ma

211. Heart Rate Control in Man 521

GojmlrJuznic, Edvard Kardelj Univ., Ljubljana,Yugoslavia

211. Heart Rate Variability Power Spectra In Normal 523

Subjects and in Patients with Cardiac Dysfunc¬tion

M.V, Kamath, McMaster Univ., Hamilton, ON

Canada; E.L. Fallen, D.N. Ghista, D. Fitchett

211. Mechanisms Leading to the Development of 525

Isovolumlc Pressure During Ventricular Relaxa¬

tion

Elie Karam, Rutgers Univ., Piscataway, NJ USA;G.M. Drzewlecki, W, Welkowitz

*- manuscript

not received

IEEE/Ninth Annual Conference of the

Engineering in Medicine and Biology Society

xxxvii

Saturday, November 14 - Morning

211. Determination of Blood Flow Velocity In Ab- 527

solute Units

Dlmlter M. Mikhov, Inst, ofNeurology, PsychiatryandNeurosurgery, Sofia, Bulgaria

211. Signal Processing Strategies to Improve Car- 529

dlac Output Thermodllutlon SNR

Richard A. Normann, Univ. of Utah, Salt Lake City,

UTUSA; R.W.Johnson

211. Hemodynamic Assessment of Calves Implanted 531

with a Left Ventricular Assist Device (LVAD)G,M. Pantalos, Univ. of Utah, Salt Lake City, UTUSA; J.D. Marks, J.B. Riebman, N.A, Burton, R.

Depaulis, W.J. Kolff

211. The Total and Collateral Blood Flow Determine- 533

tlon In Extremities by Means of Electrolm-

pedance MethodW.G. Pawllcki, Warsaw Technical Univ., Warsaw,

Poland;

211. Selective Averaging of High Resolution 535

ElectrocardiogramsHerve Rlx, Univ. of Nice, Nice, France; A. Houri,

E. Thierry, A. Varenne

211. Adaptive Control of Dog Fractional Inspired 537

OxygenJohn C. Taube, Phospho-Energetics, Inc., Philadel¬

phia, PA USA

211. A Noninvasive Method tor Simultaneous 541

Measurement of Both Axial Vascular Tensions

and Arterial Blood Pressure of SuperficialArteries

Luo Zhlcheng, Chinese Academy ofMedical Scien¬

ces, Tianjln, China; J. Wang

211. Effect of Sympathetic Stimulation on Segmental 545

Coronary Arterial Resistance In the Presence of

Coronary Stenosis In the DogLi Zhlyuan, Fourth Military Medical College, Xian,

China; S. Jlanzhoung, Z. Ylmin, W. Fuzhou

ECG Analysis I

9:45-11:15 AMSession Chair: W. Chang, L, Patomaki

213.1 A Heart Rate Transmitter That Uses a Real-Time 547

QRS Detection AlgorithmJerry J. Cupal, Univ. of Wyoming, Laramie, WY

USA; X.Yang

213.2 A Comparison of the Length and Energy Trans- 549

formations for the QRS Detection

G.P. Frangakis, Inst, of Telecommunication & Infor¬

mation, Athens, Greece; F. Qrltzall, Q.

Papakonstantinou

213.3 Feature Selection In ECQ Pattern Classification 551

G.P. Plzzutl, Univ. of Naples, Napoli, Italy

213.4 A Spectral Analysis for Human Fetal Heart Rate 553

VariabilitySuguru Suglmoto, Sagaml Inst, of Technology,Japan; Y. Noguohl, H. Hataoka, K. Maeda, H.

Kobayashi, M. Kobayashl

213.5 Improvement of Alias-Free Method for Heart 555

Rate Variability AnalysisHlroshl Hataoka, NationalDefense Academy,Yokosuka, Japan; Y. Noguchl, S. Suglmoto

213.6 ECQ Signal Analysis by Linear Predictive 557

Method

Walter H. Chang, Chung Yuan Christian Univ.,

Chung LI, Taiwan; K.-P. Lin

Inverse Problems in

Electrocardiography

9:45-11:15 AMSession Chair: Y. Rudy

214.1 Inverse Problems Based on Membrane Propaga- 559

tlon Models

Roger C. Barr, Duke Univ., Durham, NC USA;D.A, DIPerslo

214.2 Inverse Potential Field Solutions for Cardiac *

Strands of Cylindrical GeometryJohn W. Clark, Rice Univ., Houston, TXUSA

214.3 The Inverse Problem In Electrocardiography:*

Solutions In Terms of Eplcardlal Potentials

Luciano Guerri, Palazzo Dell Univ., Pavia, Italy

XXXViii IEEE/Ninth Annual Conference of the

Engineering in Medicine and Biology Society

Saturday, November 14 - Morning

CLINICAL ENGINEERING

Clinical Engineering in Radiotherapy8-9:30 AM

Session Chair: J. Rassow

204.1 Aspects of Safety and Quality Assurance In 561

Medicine — Experiences In RadiotherapyJuergen Rassow, Univ. Hospitals, Essen, West

Germany

204.2 Monte Carlo Estimation of Scattered Radiation 563

In MammographyJan Persllden, Llnkoplng Univ., Linkoping, SwedenG. A. Carlsson

204.3 A Coherent Approach In Computer-Aided 565

RadiotherapyDonnle Bakker, Catharfna Hospital, Eindhoven, the

Netherlands; M.A. Crommelln

204.4 The Potential Role of Magnetic Resonance Im- 567

aging in Radiation Oncology (with Particular

Reference to Radiotherapy Treatment Planning)H. Weatherburn, Univ. ofAberdeen, Aberdeen, UK;T.K. Sarkar, F.W. Smith

204.5 Human Imaging and Biodlstrlbutlon of 111-ln 569

Labelled S.U.V. LiposomesJ.M. Devols8elle, Lab. de Biologle Cellulaire et

Qenetlque, Lille, France; D. Coustaut, B. Weber,M.H. Laurens, C, Marchal, J. Robert, Y. Moschetto

204.6 Densitometry of Small Objects In Computed 571

TomographySlavlk D. Tabakov, Medical Academy-Plovdiv, Plov¬

div, Bulgaria

Clinical Engineering Practice

9:45-11:15 AMSession Chair: U.H, Narayanan, W, von Maltzahn

215.1 A New Generation of Helical Drains. Three- 573

Channelled Spiral Silicone Drain for Irrigationand AspirationEtlenne Levy, INSERM Centre de Chlrurgle Diges¬tive, Paris, France; J. Honlger, P. Frileux, J. Ol-

livler, J.Maslnl, E. Tlret, B. Nordlinger, L. Hannoun,

R. Pare

215.2 A Research Agenda for Clinical Engineering 576

Matthew F. Baretlch, Univ. of Iowa, Iowa City,IAUSA

215.3 For-ProfIt CE Center Under a Not-For-Proflt 578

Umbrella OrganizationW.W. von Maltzahn, Univ. of Texas at Arlington, Ar¬

lington, TX USA; J.L.Butler

215.4 The Engineering Group: Another Approach to 580

Technology Transfer In the HospitalRichard A. Sohrenker, Johns Hopkins Hosp., Bal¬

timore, MD USA; R.H. Stlefel, S.S. Mack

215.5 Albedo Measurements from Single and Binary 582

Layers of Scatterers

Asok Kumar Sinha, Regional Engineering College,S/tehar, India;

215.6 Simulation of Semf-Automatic Fluid Replace- 684

ment on Patients with CAVHJ. Kampmann, Medical School Hannover, Han¬

nover, WestGermany; G. Lau, H.G. Borst

EVOKED POTENTIALS

Evoked Potentials Estimation Sys¬tems

8 - 9:30 AMSession Chair: Z. Li-Gao, J. Simoes da Fonseca

205.1 The Study of a Method for the Estimation of 587

Evoked Potential

Erxin Zheng, Chongqing Univ., Chongqing, China;Q. Fang

205.2 Real-Time Weighted Averaging System for 589

Evoked Potentials

Edward Miskiel, Artificial Hearing Systems Corp.,Miami, FL USA; O. Ozdamar

205.3 A Low Cost EEG and Evoked Potential Analysis 591

SystemJoaquin Azpiroz, Univ. Autonoma Metropolitana-lz-tapalapa, Mexico, Mexico; V. Medina, C. Munoz,E. Saldivar, E. Sanchez, A. Pensado

205.4 An Integrated System for the Study of Serial 593

Evoked Potentials In Head ln|urlesJames J, Ackmanrt, Medical College of Wisconsin,

Milwaukee, Wl USA

205.5 Electroacupolnt Potential as Indicator of Tis- 595

sular Metabolic Dysfunction In Diabetic

Patients

C. lonescu-Tirgoviste, Clinic of Diabetes, Nutrition

andMetabolicDisorders, Bucharest, Romania; S.

Pruna

205.6 Development and Application of AuditoryEvoked Response Processor SystemJia Rul Lin, Huazhong Univ., China; F. Lie-Yi

Evoked Potentials Analysts

9:45-11:15 AM

Session Chair: T. Gasser

218.1 Comparison of Synchronous Detection 597

Methods for Sweep Stimulus VEP

EH Peli, Tuffs Univ., Boston, MA USA; G. Mc-

Cormack, S. Sokol

216.2 Evoked Potential Estimation Using a Fourier 600

Series Model

Christopher A. Vaz, Johns Hopkins Univ., Bal¬

timore, MD USA; I.N. Bankman, N.V. Thakor

216.3 Eigenvector Decomposition of Single-Trial 602

Evoked Potentials

Carlos E. Davlla, Univ. of Texas at Austin, Austin,

TXUSA; A.J, Welch, H.G. Rylander, 111

216.4 Some Statistical Methods for Variable Single 604

Brain Potentials

Th. Gasser, Zentralinstitut fur Seellsche

Gesundheit, Mannheim, West Germany; J. Mocks

216.5 A Minimal System for the Recording of Brain 606

ERPs —- Some Eplstemlologlcal Issues

J. Barahona da Fonseca, Faculty ol Medicine of

Lisbon, Lisbon, Portugal; I. Garcla-Fernandez, J.

M1ra, J, Simoes da Fonseca

*-manuscript IEEE/Ninth Annual Conference of the XXXIX

not received Engineering in Medicine and Biology Society

Saturday, November 14 - Morning

FUNCTIONAL ELECTRICAL

STIMULATION

External FES

8-9:30 AMSession Chair: G. Hammer, J. Reswick

206.1 An Evaluation Protocol for External Functional 607

Electrical Stimulation SystemsGuy S. Hammer, VA Rehabilitation R&D Evaluation

Unit, Baltimore, MD USA

206.2 A Mathematical Model to Analyze Control of 609

Upright Posture and BalanceChandler A. Phillips, Wright State Univ., Dayton,OH USA; J.R. Buhrman

206.3 Transcutaneous Transducer Garments an Ad- 611vanced System of Surface Electrodes for Func¬

tional Electrical Stimulation (FES)Herb Granek, Bio-Stlmu Trend Co., Miami Beach,FLUSA; M. Granek

206.4 Effects of Surface Electrical Stimulation of 613

Spasticity In Spinal Cord ln|ured Patients

Nancy A. Kett, Veterans Administration Hosp.,Hines, IL USA; C.J. Robinson, J.M. Bolam

206.5 Central Hemodynamic Responses to Lower- 615

Limb FNS

Roger M. Glaser, Wright State Univ., Dayton, OHUSA; S.N. Rattan, G.M. Davis, F.J. Servedlo, S.F.

Flgonl, S.C. Gupta, A.G. Suryaprasad

206.6 External Functional Electrical Stimulation*

Pierre Rabischong, INSERM U.103, Montpeller,France

Implantable Functional ElectricalStimulators

9:45-11:15 AMSession Chair: D. R. McNeal

217.1 Review of Commercially Available Implantable*

Stimulators

Donald R. McNeal, Rancho Los Amlgos Hosp.,Downey, CA USA

217.2 Development of an Implantable Electrical 618Stimulation System for Gait Applications In

Stroke and Spinal Cord Injured Patients

P.M. Meadows, Rancho Rehabilitation EngineeringCenter, Downey, CA USA; D.R. McNeal, N.Y. Su,W.W.Tu

217.3 A 4-Channel Implantable Neuromuscular 620Stimulator for Functional Electrical StimulationP.R. Troyk, Illinois Inst, of Technology, Chicago, IL

USA; J. Poyezdala

217.4 Development and Evaluation of an Externally 622

Powered, Multichannel, Implantable StimulatorBrian Smith, Case Western Reserve Univ.,

Cleveland, OH USA; P.H. Peckham, M. Gazdlk,J.E. Letechlpia, S,A. Banks, M.W. Keith

HEALTH CARE

TECHNOLOGY

Health Care Technology I

8-9:30 AMSession Chair: M.H. Dhananajaya, M. Bracale

208.1 A Simple Nuclear Instrumentation for Essential 624

ThyroldologyT,K. Dayalu, Bangalore Nursing Home Trust, Ban¬

galore, India; T.G. Krlshnamurthy

208.2 Therapeutic Devices In Neuropsychiatry 626

N. Krishnaswamy, Bangalore, India

208.3 Mobility of Aged and Handicapped 628

T.G. Krishnamurthy, Malleswaram, Bangalore, India

208.4 Hospital Instrumentation - Safety & Standardise- 629

tlon AspectsD.V.S. Raju, Elho Pvt. Ltd., Hyderabad, India;T.G. Krlshnamurthy

208.5 Maintenance of Electro Medical Equipment In 630

India

P.M. Shanker Rao, Karnataka State Electronics

Development Corp., Bangalore, India

Xl IEEE/Ninth Annual Conference of the

Engineering In Medicine and Biology Society

Saturday, November 14 - Morning

MODELING AND

SIMULATION

Physiological Measurement andControl

9:45-11:15 AM

Session Chair: A. Segui225.1 Tumor Blood Flow Measurements 632

Jorma Helkkonen, Helsinki Univ. Central Hospital,Helsinki, Finland; M. Mantyla, J. Perkkio

225.2 An Adaptive Mechanism Utilized for the Closed- 634

Loop Regulation of Blood Glucose In DiabeticsEileen A. Woodruff, Univ. of Connecticut, Storrs,CTUSA; S, Gulaya, R.B. Northrop

225.3 Experimental and Theoretical Approach to 636

Model Placental Flow

Maria Laura Costantino, Politecnico dIMilano,Milano, Italy; M.V. Ferri, R. Fumero, F.M. Mon-tevecchl

225.4 Evaluation of Discriminant Models as Control 638

Algorithms for Laser AngioplastyKenneth M, O'Brien, West Haven VA Medical

Center, West Haven, CTUSA; A.F. Qmitro, ML.Stetz, F.W, Cutruzzola, L.I. Deckelbaum

225.5 A Method for Recovering Physiological Com- 640

ponents from Dynamic Radionuclide ImagesMasahlko Nakamura, Tokal Univ. School of

Medicine, Isehara, Japan; Y. Suzuki, S.

Kobayashl, T. Takahashl

225.6 Noninvasive Evaluation In Autonomic 643

Response Using a Dual-Channel Self-BalancingElectrodermal Impedance Reactometer

Simlon Pruna, Clinic of Diabetes, Nutrition and

Metabolic Diseases, Bucharest, Romania; C. lones-

cu-Tlrgovlste, I. Mamulas, O. Bajenaru

NEUROMUSCULAR

SYSTEMS

Neuromuscular Systems III

8-9:30 AMSession Chair: C. De Luca

207.1 Simulation of Motoneuron Recruitment During 645

Nerve Stimulation

P.H. Veltink, Univ. of Twente, Enschede, the

Netherlands; J.A. Van Alste, H.B.K. Boom

207.2 Comparative Electromyography and 647

Biomechanics of Orderly and Reverse Recruit¬

ment

M. Solomonow, LSU Medical Center, New Orleans,LA USA; R. Baratta, B.H. Zhou

207.3 Electrical Stimulation of Extraocular Muscles 649

Wen H. Ko, Case Western Reserve Univ.,Cleveland, OH USA; Y. Chen, R, Richards, P.

Finger

207.4 The Eccentric Strength of Electrically Stlmu- 651lated Paralyzed Muscle

Ronald J, Triolo, Shriners Hospital for CrippledChildren, Philadelphia, PA USA; D. Robinson, E.

Gardner, R. Betz

207.5 Conduction Velocity Estimator Performance 653

Philip A. Parker, Univ. ofNew Brunswick, Frederic-

ton, NB Canada; G. McVlcar

207.6 Analysis of Anterior Cruciate Ligament Injuries *

Using Surface ElectromyographMartin A. Hunt, Vanderbllt Univ., Nashville, TN

USA; R.Shiavi

Neuromuscular Systems IV

9:45-11:15 AMSession Chair: R. Merletti

218.1 A Non-lnvaslve Device for Evaluating Fiber

Composition of Human Skeletal Muscle TypesQin Guangxia, Tianjln Univ., Tlanjin, China; M.

Pan, G. Qiang, W. Nung218.2 Design and Evaluation of a Control System for 655

the Muscle Force Regulation of Human Lower

Extremity Using Functional Electrical Stimula¬

tion

Naoakl Itakura, Keio Univ., Yokohama, Japan; K.

Fujita, K. Kubo, H. Minamitani

218.3 A Method for Attaining Natural Recruitment 657

Order In Artificially Activated Muscles

Zi-Ping Fang, Case Western Reserve Univ.,Cleveland, OH USA; J.T. Mortimer

218.4 Coactlvatlon Pattern of the Knee's Antagonist 659

Muscles

M. Solomonow, LSU Medical Center, New Orleans,LA USA; S. Hagood, B.Zhou, R. Baratta, D. Let-

son, H, Shoji, R, D'Ambrosia

218.5 Common Drive Behavior Among First Dorsal In- 661

terosseous Motor Units

Sandra Solar, Boston Univ., Boston, MA USA;C.J. De Luca, D, Stashuk

218.6 Muscle Strength Simulations Using the Artlcu- 663

lated Total Body ModelAndris Freivalds, Pennsylvania State Univ., Univ.

Park, PA USA; R. Dick

*- manuscript

not received

IEEE/Ninth Annual Conference of the

Engineering In Medicine and Biology Societyxli

Saturday, November 14 - Morning

PRIMARY HEALTH CARE

MANAGEMENT

Computer-Assisted Management ofDiabetes

8-9:30 AM

Session Chair: E. Carson

209.1 Metabolism, Chaos and the Design of Expert 665

Medical SystemsA, Mlohael Alblsser, Hosp. forSick Children, Toron¬

to, ON Canada

209.2 Insulin Administration by Various Routes *

Walter Zlngg, Hosp. for Sick Children, Toronto, On¬

tario, Canada; B.S. Leibel

209.3 Dlabeta — A Knowledge-Based System for the 667

Management of Diabetes

Ewart R. Carson, City Univ., London, UK; M.A.

Boroujerdl, F.E. Harvey, CD, Williams, P.H.

Sonksen

209.4 The Use of Insulin Pump In Diabetic Children: 669

Medical, Psychological and Economical Evalua¬

tion

Bernard Gouget, HopHal des Enfants Malades,

Paris, France; C. Levy-Marchal, J.L. Lande, P,

Czemikow

209.5 Sesam-Dlabete, An Expert System for Insulin- 671

Requiring Diabetic Patients Education

Marc Levy, INSERMU.194, Paris, France; P. Fer-

rand, J,F, Bolsvleux

REPRODUCTION MEDICINE

BioengSneering in ReproductionMedicine I

8 - 9:30 AMSession Chair: S, Guha

219.1 Technology In Fertility and Infertility 673

Sujoy K. Guha, Indian Inst, of Technology, NewDelhi, India

219.2 Measurement of the Elastic Properties of the 675

Uterine Cervix

Michael R. Neuman, Case Western Reserve Univ.,

Cleveland, OH USA; R. Kiwi, I.R. Merkatz, M.A,

Selim, A. Lyslklewloz

219.3 Monitoring of EMG and Motility of the Fallopian 677

Tube

Sneh Anand, Indian Inst, of Technology, New

Delhi, India; S.K.Guha

219.4 A Quantitative Approach to Billings Natural

Family Method

Joseph Weinman, Hebrew Univ., Jerusalem, Israel

xlii IEEE/Ninth Annual Conference of the

Engineering In Medicine and Biology Society

Saturday, November 14 - Morning

TECHNOLOGICAL ADVAN¬CES IN MODELS FOR

BIOMEDICAL RESEARCH

Technological Advances In Modelsfor Biomedical Research Symposium

8:40 AM - NOON

Session Chair: M. Eden, H. Eden

000.1 Opening Remarks

Murray Eden, Division of Research Services, NIH,

Bethesda, MD USA

000.2 Nature, Purpose and Assumption of Models In 679

Biomedical Research

J. Woodland Hastings, Harvard Univ., Cambridge,MA USA

000.3 Scaling and Biological SimilarityWilliam A. Calder, III, Univ. ofArizona, Tucson, AZ

USA

000.4 Conservation of Animals: New Approaches to

Their Use In Research

Norman Altman,

681

ULTRASOUND

Ultrasonic Imaging Systems

9:45-11:15 AM

Session Chair: M.J. Ji, Y. Fusheng

221.1 Ultrasonic Airflow Meters In Medical Applies- 682

tlon

Christian Buess, Swiss Federal Inst, of Technol¬

ogy, Zurich, Switzerland; W. Guggenbuhl

221.2 A New Type of Digital Scan Converter for the 684

Mechanical Sector-Scan Ultrasonic Imaging

SystemMin Jiang JI, Huazhong Univ. of Science & Technol¬

ogy, Wuhan, China; H.X. Wu, H.G. Kang

221.3 A Study of Acoustic Radiometer for B-Mode 686

Ultrasonic Diagnostic InstrumentJin Shuwu, Zhejiang Univ., Hangzhou, China

221.4 Evaluation of Red Blood Cell Aggregate Size by 688

Ultrasonic BackacatterlngMichel Boynard, U.E.R. Biomedicaie, Paris, France;J.C. Lellevre, R. Quillet

221.5 The Microcomputer Based Measurement for STI 690

with Doppler Ultrasound

Wel-Qi Wang, Fudan Univ., Shanghai, China; Q.-

M. Song, Q.-M. Shao

221.6 Application of a Resonance Method for Measur- 691

Ing the Size of Bubbles In an Echocontrast

AgentJoachim Slegert, Inst for Contrast Media

Research, Berlin, WestGermany; R.M. Schmitt,H.J. Schmidt, Th. Fritzsch

*- manuscript IEEE/Ninth Annual Conference of the Xliii

not received Engineering in Medicine and Biology Society

Saturday, November 14 - Afternoon

Saturday, November 14»Afternoon

BIOELECTROMAGNETSCS

Biological Effects of PulsedMicrowave Fields

1 - 2:30 PM

Session Chair: C. Rafferty234.1 Dosimetry for High Peak-Power Microwave 693

Ocular Effects Research

H. Bassen, Walter Reed Army Inst, of Research,Washington, DC USA; D. Brown, J. Trevlthick,

C.B.G, Campbell, F. Bates, C. Qambrlll

234.2 Hlstopathologlcal Studies of Rabbit Cornea Ex- 695

posed to Millimeter Waves

John R, Trevlthick, Univ. of Western Ontario, Lon¬

don, Ontario, Canada; M.O, Crelghton, M. San-

wal, D.O. Brown, H.I. Bassen

234.3 Effects of Wide Microwave Pulses on Isolated *

Nerve Cells

Frank S. Barnes, Univ. of Colorado, Boulder, COUSA

234.4 Changes In the Monkey Eye Following Pulsed 698

2.45-GHz Microwave ExposureHenry A. Kues, Johns Hopkins Univ., Laurel, MD

USA; S.A. D'Anna

234.5 Effects of Pulsed Microwave Fields on Soluble 701Proteins and LiposomesCharles N. Rafferty, Walter Reed Army Inst, of

Research, Washington, DC USA; J. Knutson

234.6 Effects of Pulsed High Power Microwaves on*

Animal Behavior

John De Lorge, Naval Air Station, Pensacola, FLUSA

Manipulation of Cells by HighIntensity Electric Fields I

2:45-4:15 PM

Session Chair: J. Weaver

244.1 Manipulation of Cells by High Intensity Electric *

Fields

E. Neumann

244.2 Pulsed Electric Field Induced ATP Synthesis by*

Mitochondrial ATPase

Tian Y. Tsong, Johns Hopkins Univ. School of

Med., Baltimore, MD USA; F, Chauvin, R. D, As-tumian

244.3 Producing Monoclonal Antibodies by 703

Electrofusion

Mathew M.S. Lo, National Inst, on Drug Abuse, Bal¬

timore, MD USA; T.Y. Tsong

244.4 Electroporatlon: A General Method of Gene 705Transfer

Huntington Potter, Harvard Medical School, Bos¬

ton, MA USA

244.6 Electroporatlon In Individual Cells: Measure- 708ments Using Light Scattering and Fluorescence

by Flow CytometryJames C. Weaver, Massachusetts Inst, of Technol¬

ogy, Cambridge, MA USA; J.Q. Bliss, G.I. Har¬

rison, J.R. Mourant, K.T, Powell

Manipulation of Cells by HighIntensity Electric Fields II

4:30 - 6 PM

Session Chair: J. Weaver

261.1 Frequency-Dependent Orientation of Ellipsoidal 710

Particles In AC Electric Fields

Ruth Douglas Miller, Univ. of Rochester,Rochester, NY USA; T.B. Jones

261.2 Skeletal Muscle Cell Rupture by Pulsed Electric 712

Fields

Raphael C. Lee, Massachusetts Inst, of Technol¬

ogy, Cambridge, MA USA; D.C. Gaylor, K. Prakah-

Asante, D. Bhatt, D.A. Israel

261.3 Mechanism of Transfer and Integration of 715

Genes Introduced Into Hematopoietic Cells byElectroporatlonFrances Toneguzzo, EQ&G Biomoiecular, Water-

town, MA USA; A, Keating

261.4 A Stochastic Theory of Electroporatlon 717

Istvan P. Sugar, Univ. of Virginia, Charlottesville,VAUSA

261.5 The Use of Electric Field-Mediated DNA Trans¬

fer In the Study of Structure

YohtarohTakagakl, Massachusetts Inst, of Tech¬

nology, Cambridge, MA USA; K. Maeda, O.

Kanagawa

281.6 Quantitative Theory of Electroporatlon: Present 719

Status

James C. Weaver, Massachusetts Inst, of Technol¬

ogy, Cambridge, MA USA; K.T. Powell

xliv IEEE/Ninth Annual Conference of the

Engineering In Medicine and Biology Society

Saturday, November 14 - Afternoon

BIOENGINEERING

CHALLENGES

IN DENTISTRY

Dentistry

1 - 2:30 PM

Session Chair: M. Jeffcoat

237.1 Integrated Craniofacial Data Analysis System 721

Sheldon Baumrlnd, Univ. of California, San Francis¬

co, CA USA; S, Curry

237.2 Realtime Mandibular Motion Analysis 723

Sean Curry, HMS Ltd., Boulder, CO USA; S.

Baumrlnd

237.3 Signal Processing for Cementoenamel Junction 725

Detection During Periodontal ProbingRobert L. Jeffcoat, Analytic Sciences Corp, Read¬

ing, MA USA; M.K. Jeffcoat, K. Captain

237.4 Dlphosphonate Bone Scanning for the Detec- 727

tlon of Active Periodontitis

Marjorle K. Jeffcoat, Harvard School of Dental

Medicine, Boston, MA USA; R.C. Williams, M.S.

Reddy, R. English, B.L. Holman, P. GoWhaber

237.5 A Versatile Pocket Dental Sono-Explorer 729

Shlxu Xu, Fourth MilitaryMedical College, Xian,China; D. Jiang, L. Huang

237.6 Computerized Cephalometry and Cranlo-Faclal 731

Correction Assisted

Frederlo Rlvoalan, INSERM U.279, Lille, France;J.P. Sozanskl, Y, Moschetto, M. Boniface

BIOMECHANICS

Postural Stability and Control I

1-2:30 PM

Session Chair: K. Barin

238.1 Signal Processing of Thin Film Neural Record- 743

ing Array Data to Separate Channels of Point

Process Information

David J. Anderson, The Univ. ofMichigan, AnnArbor, Ml USA; B. Clopton, D. Klpke

238.2 Human Postural Sway Responses to Trans la- 745

tlonal Movements of the Support Surface

Kamran Barin, Ohio State Univ., Columbus, OHUSA

238.3 Studies of Motor Unit interaction In Human 748

Muscle

Carlo J. De Luca, Boston Univ., Boston, MA USA;G. Kamen, S. Solar, D. Stashuk

238.4 A Subsystem Performance Based Model for 749

Postural StabilityGeorge V. Kondraske, Univ. of Texas at Arlington,Arlington, TXUSA

238.5 A Constrained Feedback Model of the Human 751

Postural Control SystemMakoto Yoshizawa, Faculty of Engineering, Sen-

dai, Japan; H. Tanaka, H.S. Lin, H. Takeda

238.6 Computer Assisted Analysis of Leg Length DIs- 753

crepancleaJohn M. Martell, Univ. of Chicago, Chicago, IL USA;D. Cooperman, D. Kucharzyk, E.A, Millar

Imaging

2:45-4:15 PM

Session Chair: P. Desjardlns248.1 An Update on the State-of-the-Art of CAD/CAM 733

In Dental Prosthodontlca

E, Dlanne Rekow, Univ. of Minnesota, Minneapolis,MN USA; A.G. Erdman, T.M. Speidel

248.2 Three-Dlmenslonal Imaging In Dental Radlog- 735

raphyUrs E. Ruttimann, National Inst, of Dental

Research, NIH, Bethesda, MD USA; R.L, Webber

248.3 A Technique for Real Time Measurement of 737

Human Tooth EruptionRobert L. Paterson, IPD, IBM, Lexington, KY USA;

R.A. Maddox, W.R. Proftit, B.C. Wright

248.4 Feature Extraction In Dental Radiographs 739

Stanley M. Dunn, Rutgers Univ., Piscataway, NJ

USA; P.J. Desjardlns, M. Milles

248.5 Quantitative Description of the Trabecular Pat- 741

tern of Bone In Osteoporotic Patients

Paul F. van der Stelt, Academic Center for Den¬

tistry, Amsterdam, The Netherlands; W.G.M.

Qeraets

Postural Stability and Control II

2:45-4:15 PM

Session Chair: H. Hemami

252.1 Postural Stability: Frequency Domain 755

Considerations

Gerald F. Harris, Marquette Univ., Milwaukee, Wl

USA; S.A. Rledel, D.V. Mates!

252.2 Postural Adaptations to Induced Body Sway 757

Robert D. Andres, Univ. ofMassachusetts, Am¬

herst, MA USA

252.3 Hooshang Hemani, Ohio State Univ., Columbus,*

OH USA

252.4 Conrad Wall, III, Depf. of Otolaryngology, Boston,*

MA USA

252.5 Experimental Evidence tor a Random Process 759

Model of Postural Sway

Serge H. Roy, Boston Univ., Boston, MA USA; 1.

Ladin, C.J. De Luca

- manuscriptnot received

lEEBNInth Annual Conference of the

Engineering In Medicine and Biology Society

xlv

Saturday, November 14 - Afternoon

Models and Measurement

4:30 - 6 PM

Session Chair: P. Ask

262.1 Various Models Describing Urethral Flow 761P. Ask, Linkoping Univ., Linkoping, Sweden; A.

Engberg, A. Spangberg, H. Terio

262.2 Cross-Sectional Area Measurements of the 763Human Chestwall

Richard Sartene, Univ. Paris Sud, Orsay, France;Ph. Martinot-Lagarde, M. Mathieu, A. Vincent, G.

Durand

262.3 Measurement of Arterial Blood Pressure and 765

Elastic Properties In Human FingerHideaki S. Shlmazu, Kyorin Univ., School of

Medicine, Mitaka-Shl Japan; A, Kawarada, H.

Kobayashl, H. Ito, K. Yamakoshi

262.4 Effect of Different Parameters of Motion In Car- 767

dlac Wall Motion AnalysisR. Sal Prasad, Indian Inst, of Technology, Madras,India; T.M. Srlnlvasan

262,6 Noninvasive Assessment of Whole Arm Arterial 769

Elastic Properties In HumansJ.Z. Wang Rutgers Univ., Plscataway, NJ USA; ,

W.M.Shi, T.J. Wang, J.K.J. Li

262.6 Use of Blomechanlcal Data Obtained by 771Robots: A Therapeutic ApplicationMichael R. Zomlefer, Santa Clara Univ., Santa

Clara, CA USA; D, Khalili

BIOPHYSICS

Channel Dynamics

1-2:30 PM

Session Chair: A. Rega236.1 Calcium Pump Dynamics 773

A.J. Caride, Mayo Clinic, Rochester, MN USA;A.F. Rega

236.2 The Measurement Experiment of Electric 775

Properties of Tumor Tissues

Hu Yong, Tlanjin Univ., Tianjin, China; Wang MingShi

236.3 Observed Open and Closed Durations of Single *

Channels Recorded from the Corneal

Larry S. Liebovitch, Columbia Univ., New York, NY

USA

236.4 Kinetics of Neurotransmitter Chemoreceptlon 777In Central Control of BreathingBernard Hoop, Massachusetts General Hospital,Harvard Medical School, Boston, MA USA; H.Kazeml

236.5 Calcium Gradients Measured with a Vibrating 779

Calcium-Selective Electrode

Lionel F, Jaffe, Marine Biological Laboratory,Woods Hole, MA USA; S. Levy

xlvi IEEE/Ninth Annual Conference of the

Engineering In Medloine and Biology Society

Saturday, November 14 - Afternoon

BIOSENSORS

Glucose Sensors I

1 - 2:30 PM

Session Chair: R. Peura, Y, Mendelson

239.1 Configurations! Cyclic Vottammetry: Increasing 782

the Specificity and Reliability of ImplantedElectrodes

Leland C. Clark, Jr., Children's Hospital ResearchFoundation, Cincinnati, OH USA; R.B. Spokane,T.L. Stroup

239.2 Assessment of MicroelectronicTechnology for 784

Fabrication of Electrocatalytlc Glucose Sensor

Jan J. Lewandowskl, The Cleveland Clink Founda¬

tion, Cleveland, OH USA; P.S. Malohesky, M.

Zborowski, Y. Nose

239.3 Feasibility of the Palpebral Conjunctiva as a 786

Site for Continuous, Noninvasive Glucose

MonitoringGusGlaser, Worcester Polytechnic Inst., Wor¬

cester, MA USA; R.A. Peura, Y, Mendelson, A.

Shahnarlan

239.4 The Feasibility of an Implantable Opto- 788

Electronic Qlucose Sensor

Dorothea E, Burk, Univ. of Florida, Gainesville, FL

USA; I.e. Arrleta, CD. Batloh

239.5 Qlucose Concentration Measurement in Water 790

Using a CO2 Laser Based Attenuated Total

Reflection Method

Been-Chyuan Lin, WorcesterPolytechnic Institute,Worcester, MA USA; A, Clermont, Y. Mendelson,R.A. Peura

239.6 In Vitro Blood Qlucose Measurement Using A 792

CO2 Laser Based Attenuated Total Reflection

TechniqueAllen Clermont, Worcester Polytechnic Institute,

Worcester, MA USA; B. Un, R.A, Peura, Y, Men¬

delson

Glucose Sensors II

2:45 -4:15 PMSession Chair: R. Peura, Y. Mendelson

253.1 A Method for Electrochemical Glucose Sensing 794

Employing Electrochemical Regeneration byVoltage PulsingLap-TakChan, Montefiore Hospital, Pittsburgh, PA

USA; D.L Foley, S.J. Yao, M.A. Krupper, S.K,

Wolfson, Jr.

253.2 Electrocatalytlc Qlucose Sensor 796

S. Sarangapanl, Qiner, Inc., Waltham, MA USA; J.

Qlner, J,S, Soeldner, O.K. Colton, Q, Plcha, K.G.

Mayhan, R.F. Drake

253.3 A Thick Film Glucose Sensor 7'98

M. Lambreohts, Katholleke UntversHeit Leuven,

Heveriee, Belgium; J. Suls, W. Sansen

253.4 Panel Discussion

Chemical Sensors

4:30 - 6 PMSession Chair: Y. Mendelson, R, Peura

263.1 Polyvinyl Alcohol as a Matrix for Indicators for 800

Fiber OpticChemical SensorsW. Rudolf Seltz, Univ. ofNew Hamphsire, Durham,NH USA; Y. Zhang, C.L. Grant, R. Russell, Z.

Zhujun, W.H. Ma, D. Sundberg

263.2 Fiber Optic Biosensors for in vivo and In vitro 802

Measurements of Clinically Important SpeciesDavid R. Walt, Tufts Univ., Medford, MA USA; C

Munkholm, P. Yuan, S. Luo

263.3 Correlation Between pH-ISFET Performance 804

and Process Conditions of pH-SensltlveAluminum Oxide Films

Anthony S. Wong, Case Western Reserve Univ.,

Cleveland, OHUSA; P.W. Cheung

263.4 Measuring Oxygen Saturation and Hematocrit 807

Using a Fiberoptic Catheter

Gene A. Bornzin, Spectramed Inc., Oxnard, CA

USA; Y, Mendelson, B.L. Moran, A.F, Willis, S.

Gellert, R. Buxton

263.5 Optical Sensor for Hb Content and Oz Satura- 810

tlon: Design, In Vitro and In Vivo Evaluation

Setsuo Takatanl, Research Inst, Suits, Japan; H.

Noda, H. Kohno, H. Takano, H. Noda, T. Akutsu

263.6 A Two-Flux Kubelka-Munk Model for Transmls- 813

slon Pulse OximetryJoel C. Kent, Worcester Polytechnic Inst, Wor¬

cester, MA USA; Y. Mendelson

*- manuscript IEEE/Ninth Annual Conference of the Xlvii

not received Engineering In Medicine and Biology Society

Saturday, November 14 - Afternoon

BIOSIGNAL PROCESSING

Poster Session:

Signal and Image Processing I

1-3:15 PM

241. 24-Hour Biological Signal Analysis Via Or- 815

thogonal Search Method - A Comparison to FFTStephen J. Berry, Univ. of California, Los Angeles,CA USA; D.Franco, C. Schwartz

241. Evolution Adaptation of Color Information*

Processing In the Retina of Fish

Kenkkiohi Fukurotani, Toyama Univ., Toyama,Japan; Fih Harosl

241. Spatial Aliasing Effects on the Transfer Func- 817tlon of Filtered BackprojectlonStephen J. Glick, Univ. of Massachusetts Medical

Center, Worcester, MA USA; M.A. King, B.C. Pen¬

ney,

241. A Step Toward Objectifying Abnormality In Non- 819

verbal Speech Using Vector Quantization

Dong Hsu, Northeastern Univ., Boston, MA USA;J.R. Deller, Jr., L.J. Ferrler, D.H. Brooks

241. Measurement of Sensory-Motor Function Fol- 821

lowing Unilateral Cerebral Infarction

Richard D, Jones, Christchurch Hospital,Chrlstchurch, NewZealand; I.M. Donaldson, P.J.

Parkin, S.A, Coppage241. A Real Time Algorithm for Auto Analysis and 823

Diagnosis of ECG

P.P. Krlshnapur, Defence Bioenglneering andElectromedical Laboratory, Bangalore, India; B.V,

Ramesh, CA. Verghese

241. Triple Gamma Coincidence Tomographic Imag- 826

Ing Without Image ProcessingZ. Liang, Monteflore Medical Center, Bronx, NY

USA; H. Hart, A. Schoenfeld

241. A General Solution to a Large Class of Regres- *

slon Problems

George Malachowskl, Catalyss Corporation,Englewood, CO USA; Brian Hall, Robert Ashcroft

241. Design of A Flexible Syntactic Pattern Recognk 827

tlon SystemJohn E. Milton, McMaster Univ., Hamilton, ONCanada; I. Bruha, A.R.M. Upton, G. Madhavan

241. 3D: An Application to SPECT Data 830Antonio Sousa Pereira, Universidade de Aveiro,Avelro, Portugal

241. Spectral Analysis and Digital Filtering with 16- 832Bit Fixed Point Hardware

Paul H. Sohlmpf, Univ. of Washington, Seattle, WA

USA; Y. Kim

241. Initial and Final Patterns of a Cell Matrix to 834Determine Cell Cycle Parameters

A.B. Youssef, Cairo Univ., Cairo, Egypt; M, El-Tawll

241. The Fourier and Walsh Power-Spectrum 836

Analysis of EEG

Shouchang Zhou, Chongqing Univ., Chongqing,China; H. Yang

241. The State-Compressed Spectral Array for EEG 838

Shouohang Zhou, Chongqing Univ., Chongqing,China; J. Luo

Poster Session:

Signal and Image Processing li

3:45-6 PM

267, Time Domain Analysis for the Detection of Ar- 840

tefacts In E.E.G.

A.M. Desodt, Centre d'Automatlque, Lille, France;C. Rajagopalan, A. Nakrachi, J.M. Jacquesson

267. Motion and Temperature Monitoring System 842

Dragan Dugandzic, Cleveland State Univ.,

Cleveland, OH USA; L.S. Stern, J.B. Senturla

267. Centre of the Mass Supported by Each Vertebra 844on a 3 D Image of the SpineGinette Duval-Beaupere, HopHal R. Poincare, Gar-

ches, France; J. Hecquet, J. Dubousset, H. Graf,C. Tabuteau, P, Roche

267. Techniques to Enhance Interpretation of Func- 846tlonal Cardiac Images from PET

Keri W. Hicks, Univ. of Texas Health Science

Center, Houston, TXUSA; R.W, Rows, K.L. Gould

267. Pattern Recognition In the Vocal Expression of 2090

Emotional CategoriesAlfonso Jlmenez-Fernand, Socialy Metodoiogia,Madrid, Spain; F, Del Pozo, C. Munoz, J.L. Zoreda

267. A Computer-Aided Technique for Long-Tlme *

Gastric pH MonitoringZhang Kal, Huazhong Univ. of Science A Technol¬

ogy, Wuhan, China; Lin Jla Rul

267. Spikes Detection Approach for the Classifies- 848

tlon of Epileptic Patients from the EEG

M. Sherin A. Kamel, Cairo Univ., Cairo, Egypt;M.E.M. Rasmy, O.I. Madkour, A. Rashwan

267. Estimation of Diastole to Systole Changes from 850Cardiac PET ImagesN. Kehtarnavaz, Texas A&M Univ., College Sta¬

tion, TX USA; M.Z. Win, N. Mullanl

267. A Comparison of Smoothing and Digital Filter- 852

Ing/Dlfferentlatlon of Kinematic DataM.C Murphy, Massachusetts Inst, of Technology,Cambridge, MA USA; R.W. Mann

267. A New Approach to Microprocessor Based 2100

ECG/EEG AnalysisU.H. Narayanan, CSIR Madras Complex, Madras,India; G. Subramanian, S.R. Gowarlker

267. Insight to Critical Flicker Frequency Through 854Evoked Potentials

Radu M. Negoescu, Inst, of Hygiene & Public

Health, Bucharest, Romania; I.E. Cslkl

267. A Stimulation Waveform for a TVSS which Mini- 856

mlzes Power ConsumptionEnrico Nunzlata, Ohio State Univ., Columbus, OHUSA; P. Taige, L.L. Lipetz, H.R. Weed

xlviii IEEE/Ninth Annual Conference of the

Engineering In Medicine and Biology Society

Saturday, November 14 - Afternoon

267. Adaptive Enhancement of Human 858

ElectrogastrographyW. Sansen, Katholleko Univ., Leuven, Belgium; J.

Chen, J. Vandewa/le, G. Vantrappen, J. Janssens

267. EOG Canceling In EEG: An Adaptive Filter Ap- 860

proach for ERP Estimation

Kazuo Yana, HoselUniv., KoganeiCity, Japan; M.Fukuda, N. Takano

267. The Study of A Method for the Estimation ofEvoked Potential

Erxln Zheng, Chongqing Univ., Chongqing, China;QiFang

267. A Computer-Aided Technique for Long-Term 862

Gastric pH MonitoringKal Zhang, Huazhong Univ. of Science and Tech¬

nology, Wuhan, China; J.R, Lin

CARDIAC MODELS

Cardiovascular Dynamics I

2:45-4:15 PMSession Chair: R.I. Kitney

254.1 Investigation of Blood Flow In Veins 864Subir Kar, Indian Inst, of Technology, Bombay,India

254.2 A Scheme to Educe Organized Flow Structures 866In Pulsatile Flows

Tak Kee Cheung, Naval EnvironmentalPredictionResearch Facility, Monterey, CA USA

254.3 A Model for the Prediction of Pressure Pulse 868

Contours In the Ascending Aorta

A. Chatterjea, Indiana Univ.-Purdue Univ., FortWayne, IN USA; J.N. Libii

254.4 Velocity Profiles In Stenosed Models Using 870

Magnetic Resonance ImagingStanley E. Rittgers, Virginia Commonwealth Univ.,Richmond, VA USA; D.Y. Fei, K.A, Kralt, P.P.Fatouros

254.5 Couple-Stresses In Two Fluid Model for Blood *

Flow In Artery with Mild StenosisPrawal Sinha, Indian Inst, of Technology, Kanpur,India; T.S. Pal, A.P. Dwivedi

254.6 Rheocardlography for Assessment of Sys- 872

tematlc, Pulmonary and Coronary Blood Flow

Tadeusz Palko, Warsaw Technical Univ., Warsaw,Poland; J. Weglerz

Cardiovascular Dynamics II

4:30-6 PMSession Chair: CM. Rodklewicz, T. Palko

264.1 Simulation of the Coronary Hemodynamics 874

Using A Comprehensive Analog Model

Ylng Sun, Univ. of Rhode Island, Kingston, Rl USA;A. Mo, H. Gewirtz

264.2 On the Arterial Flow of the Whole Blood

Czeslaw M. Rodkiewlcz,Ph.D, Univ. of Alberta, Ed¬

monton, AL Canada; P. Sinha, J, S. Kennedy264.3 Mitral Valve Flow and Its Relation to Pressure 876

Gradient Halftlme

Dan Loyd, Linkoping Univ., Lingkoping, Sweden;P. Ask, B. Wranne

264.4 Vasoconstrictor Drug Effects on Vascular Com- 878

pflance by Pulse Contour AnalysisStanley M, Finkelstein, Univ. ofMinnesota, Min¬

neapolis, MNUSA; J. Mock, J.B. Eaton, G. Hat¬

field, J.N. Conn

264.5 Assessing Wave Reflections In the Systemic 880Arterial TreePamela S. Geipel, Rutgers Univ., Piscataway, NJUSA; J. K-J LI

264.6 Cutaneous Pressure Photoplethysmography for 882

Evaluating Vascular Disease

Lee E. Ostrander, Rensselaer Polytechnic Inst,

Troy, NY USA; B.Y.Lee, W.Cui

*- manuscript IEEE/Ninth Annual Conference of the ilnot received Engineering in Medicine and Biology Society

Saturday, November 14 - Afternoon

CARDIOLOGY

Modeling Cardiac Electrical Activityat the Cellular Level

1 - 2:30 PMSession Chair: R. Plonsey

240.1 Membrane Mechanisms of Ion Transport 885

J. Mallen Kootsey, Duke Univ. Medical Center, Dur¬

ham, NC USA

240.2 Electrogenesls and Regulation of the Currents 887

Underlying the Cardiac Action Potential and

Propagation MechanismsNicholas Sperelakis, Univ. ofCincinnati, Cincinnati,OH USA

240.3 Mathematical Modeling of Cylindrical Strands

of Tissue from the Frog Heart

John W. Clark, Rice Univ., Houston TXUSA

Heart Rate Control in Man II

2:45-4:15 PMSession Chair: P. Langhorst

242.1 Heart Rate Control In Man Under Bloengtneer'a 889

ScrutinyR. Negoescu, Inst of Hygiene & Public Health,Bucharest, Romania

242.2 Dynamic Organization of the Central Nervous 891

System for Cardiovascular, Respiratory andSomatomotor RegulationPeter Langhorst, Free Univ. of Berlin, Berlin, West

Germany; M, Lambertz, G. Schulz

242.3 Initial Heart Rate Response to Standing 893Cornelius Borst, Univ. Hospital, Utrecht, TheNetherlands

242.4 Mechanism of Blood Pressure Oscillation In 895Man and Animal

Klyoshl Mlyakawa, Shlnshu Univ. School of

Medicine, Matstumoto, Japan242.5 Simulating the Strength of the Heart Beat 897

Gojmir Juznic, Edvard Kardelj Univ., Ljubljana,Yugoslavia; I. Emri, B. Struna, D. Petereo, B. Knap

242.6 An Analysis of the Relationship of Heart Sound 899Time Intervals to Respiratory Sinus ArrhythmiaCharles S. Lessard, Texas A&M Univ., College Sta¬

tion, TXUSA; E.T. Schorsch

ECG Analysis 19

2:45-4:15 PMSession Chair: I.G. Durand

243.1 Cardiac Arrhythmia Analysis Using Hidden 901Markov Models

Douglas A. Coast, Carnegie Mellon Univ., Pit¬

tsburgh, PA USA; R.M, Stern, G.G. Cano, S.A.

Briller

243.2 Adaptive Prediction and Location of R-R Inter- 904

vala from Holter TapesDavid S. Buckles, Medical Univ. of South Carolina,Charleston, SC USA; L.L. Ewing, B.A. Ross

243.3 Digital Signal Processing of the Phonocar- 906

dlogramLouTs-Gllles Durand, Clinical Research Inst, of

Montreal, Montreal, QU, Canada

243.4 On Adaptive Noise Cancelling for ECG Signal 908

Jun-Rong Xu, Shanghai Jlao-Tong Univ., Shan¬

ghai, China; Xia-QI Liu, Zhl-Zhong Wang

243.5 Long Term Monitoring of Variability In ECQ

Laurl Patomakl, Univ. of Kuoplo, Kuoplo, Finland;E. Lanslsmles, M. Pletlkalnen, K. Tahvanalnen, E,Vahnlnen

243.6 The Syntactic Approach to ECG Analysis 910

E. Skordalakls, National Technical Univ., Divisionof Computer Science, Athens, Greece

Cardiac Monitoring Instrumentation

4:30 - 6 PM

Session Chair: W. Smith

265.1 An Experimental ECQ Scanning System 912Kenneth P, Blrman, Cornell Univ., Ithaca, NY USA;J. Touch

265.2 A Time-Sharing Computer System for Rhythm 914

Analysis of Long-Term ElectrocardiographicData

Edward V. Simpson, Duke Univ. Medical Center,

Durham, NC USA; A.A. Lastra, E.L.C Prltohett,W.M. Smith

265.3 A Real-Time Device for 12-Lead Ischemia *

MonitoringI.M. Adams; M.W. Kruooff, J,E, Pope, D.W.Mortara, G.S. Wagner

265.4 An Ambulatory Cardiac Output Monitor 916

William N. Reining, Phoenix Engineering and Com¬puting Inc., Madison, Wl USA; W.J. Tompkins,J.G. Webster

265.6 Ventricular Fibrillation Detection by Sequential 918

Hypothesis TestingN.V. Thakor, Johns Hopkins Univ., Baltimore, MDUSA; Z. Yi-Sheng

I IEEE/Ninth Annual Conference of the

Engineering In Medlolne and Biology Society

Saturday, November 14 - Afternoon

COMPUTERS IN MEDICINE EEG ANALYSIS

Expert Systems I

1 - 2:30 PM

Session Chair: I.S.N. Murthy, C. Hernandez-Sande227.1 An Expert System for Use In Augmentative 920

Communication Device PrescriptionBrian L. Robey, Louisana Tech Univ., Ruston, LA

USA; S.A. Napper, P.C. McAfee

227.2 Nonverbal Message Generation by a Frame 922Controlled Language Graph Search

Bon-Klem Sy, Northeastern Univ., Boston, MA USA;J.R. Deller, Jr.

227.3 Al and SPR Approach to Diagnosis of

NeurowaveformsB. Ramabhadran, Anna Univ., Madras, India

227A Knowledge-Based Analysis and Understanding 924of 3D Anatomical and Functional ImagesAtam P. Dhawan, Univ. of Houston, Houston, TXUSA; S. Juvvadl, H. Baxi, N. Mullanl

227.5 Mathematical Methods for Computerized Ad- 927ministration of IV Narcotics

Daniel B. Raemer, Brigham and Women's Hospital,Boston, MA USA; H.R. Raemer

227.6 Septicemia Expert System 929

Regis Beusoart, CERIM-Faculte de Medecine,Lille, France; C. Beuscart, A. Duhamel, SES Group

Expert Systems II

4:30 - 6 PM

Session Chair: B. Auvert, J. Bourne

260.1 Helens: Understanding Natural Language Medl- 931

cal ReportsPierre Zwelgenbaum, INSERM U.194, Paris,France; B. Bachlmont, J, Bouaud, M, Cavazza, L.

Dore, J.F. Bolsvleux, A. Aurengo

260.2 An Expert System for the Recognition of 933

Anatomical Organs from 3D Data-BaseGianni Vemazza, Univ. ofGenoa, Geneva, Italy;S. Delleplane, S.B. Serplco, S. Bruzzone, C.

Regazzoni

260.3 Similarity-Based Reasoning as a Paradigm In 935

Artificial IntelligenceJuan E, Vargas, Vanderbtlt Univ., Nashville, TN

USA; J.R. Bourne, C Saggese

260.4 An Expert System for Preliminary Diagnosis of *

Cardiac Signalsl.K. Sandhya, Madras, India

260.6 Hand Held Computers and Medical Decision 937

MakingBertran Q, Auvert, INSERM U.88, Paris, France;P. Aegerter, P, Boutin, D, Bos,

260,6 A Fuzzy Relation Model for Multifactorial

Analysis of Cerebrovascular Diseases

Shouchang Zhou, Chongqing Univ., Chongqing,China W.W. Dong, L.C Wang

EEG Analysis I

4:30-6 PMSession Chair: R.A.F. Pronk

257.1 Inhomogeneous Head Model for Dlpole Tracing 939

In the Brain

Bin He, Tokyo Inst, of Technology, Yokohama,Japan; W. Ye, Y. Okamoto, T. Musha

257.2 Brain Death and EEQ Alpha: An 941

Electromechanical Phenomenon

Horace T. Castillo, St. Anthony's Hospital, St.

Petersburg, FL USA; D. Sapoznikov

257.3 Blspectral Analysis of the EEG During Various 943

Vigilance States

Taikang Ning, Trinity College, Hartford, CTUSA;J.D, Bronzlno

257.4 An Animal Quantitative Pharmaco-Electroen- 945

cephalographlcal ModelAndras Ambrus, Chemical Works of Qedeon Rich-

terLtd., Budapest, Hungary; A. Sarkadl

257.5 An Analysts of Brain and Neuron Electrical Ac- 947tlvltles

Wen Xiao Yang, Huazhong Univ. of Science &

Technology, Wuhan, China

257.6 A Geometric Model of the EEG Using Tensor 949

Analysis on Manifolds

Thomas J. Collins, III, Krug International, Houston,TXUSA

'- manusorlptnot received

IEEE/Ninth Annual Conference of the

Engineering in Medicine and Biology Society

Saturday, November 14-Afternoon

EVOKED POTENTIALS

Sensory Evoked Potentials

1 - 2:30 PM

Session Chair: K.W. Plattig

228.1 Classification of Brainstem Auditory Evoked 951

Potentials Using Time and Frequency Domain

Features

D.N. Ghista, McMaster Univ., Hamilton, ON

Canada; M.V. Kamath, S.N. Reddy, A.R.M. Upton,R.J, Duke, W. Kinsey, M,E. Jernlgan

228.2 The Frequency-Domain Analysis of Brainstem 953

Auditory Evoked Potential

Xiao-bo Ma, Tsinghua Univ., Beijing, China; S.

Gao, L. Zhou, H. Pel, W. Jlng

228.3 Development and Application of Auditory 956

Evoked Response Processing SystemJla Rul Lin, Huazhong Univ. of Science & Technol¬

ogy, Wuhan, China; L.Y. Fang

228.4 Detection Criteria for Sensory Evoked Potentials 957

J, Robert Boston, Univ. of Pittsburgh, Pittsburgh,PA USA

228.5 Models of Single Sweep Processing of VEP's In 959

Neurophysiologies! and Clinical Studies

Diego Llberatl, PolHechnlco DiMllano, Milano, Italy;G, Baselll, S. Cerutti, G. Pavesi

228.6 Gustatory and Olfactory Evoked Potentials In 961

Man

Karl-Heinz Plattig, Frledrlch-Alexander Univ., Erlan-

gen, West Germany

VEPS

2:45-4:15 PM

Session Chair: E. Mlchell-Tzanakou

245.1 Effects of Contrast on Temporal Filters In the 963

Human Visual SystemVance Zemon, The Rockefeller Univ., New York,NY USA; M. Conte, J. Camlsa

245.2 A VEP Study of Interactions Due to Flicker and 966

Drift

Brett T. Foxman, Cornell Univ. Medical College,New York, NY USA; J.D. Victor

245.3 Visual Evoked Potential Extraction by Adaptive 968

FilteringS.J. Orfanidis, Rutgers Univ., Piscataway, NJ USA;F. Aafif, E. Mlchell-Tzanakou

245.4 Long Term Habituation Effects on the Visual 970

Evoked Potential

John E. Ingeholm, Jr., Rutgers Univ., Piscataway,NJ USA; P.S. Gelpel, E. Mlchell-Tzanakou

245.5 VEPS

Banu Onaral,

245.6 Blsensory Evoked Potentials 972

Jorge I. Aunort, Purdue Univ., West Lafayette, IN

USA; J. Garrett, Z. Keirn, G. Mouchawar, M,

Seeliger

FUNCTIONAL ELECTRICAL

STIMULATION

Scoliosis

1 - 2:30 PM

Session Chair: M. Herbert

229.1 Scoliosis - the Problem 2088

M. Herbert, Toronto, ON Canada

229.2 Surface Stimulation for Scoliosis *

C. Brown, Denver, CO USA

229.3 New Developments In the Design of Surface 974

Stimulation Electrodes

Jens Axelgaard, Axelgaard Manufacturing Co. Ltd.,

Fallbrook, CA USA

229.4 Electrode Vest for Scoliosis Treatment with Sur¬

face Stimulators

Herb Granek, Bio-Stimu Trend Co., MiamiBeach,

FLUSA

229.5 Psychological Studies of Children with

Scoliosis Treated by Bracing In Electrical

Stimulation

N. Kahanovitz, New York, NY USA

229.6 Treatment of Scoliosis Using Implantable 2086

Muscle Stlmulatlors (ESI)M. Herbert, Toronto, ON Canada

Organ Control

2:45-4:15 PM

Session Chair: J, Myklebust246.1 Physiological Effects of Spinal Cord Stimulation

*

Joel B. Myklebust, Medical College of Wisconsin,

Milwaukee, Wl USA; Joseph F. Cuslck

246.2 Control of Spasticity In Spinal Cord Injury 977

through Spinal Cord Stimulation

Arthur M. Sherwood, Baylor College ofMedicine,Houston, TX USA

246.3 Optimization of Sacral Stimulation for Bladder 979

Function In Chronic Spinal DogJames Walter, Hines V.A. Hospital, Hines, IL USA;C.J, Robinson, J.S. Wheeler, R.D. Wurster

246.4 Stimulation of the Spinal Cord for Spasticity: 981

Experimental Results

Dennis J, Maiman, Medical College of Wisconsin,

Milwaukee, Wl USA; J.B. Myklebust, G. Barolat

246.5 D.C. Electrical Fields and Peripheral Nerve 983

RegenerationJames Kerns, Rush-Presbyterian St. Luke's Medi¬cal Center, Chicago, IL USA

,t IEEE/Ninth Annual Conference of the

Engineering In Medicine and Biology Society

Saturday, November 14 - Afternoon

External Electrodes

4:30-6 PM

Session Chair: L. Baker

258.1 Determination of the Current Density Dlstrlbu- *

tlon Under the Electrode

Yongmin Kim, Ph.D., Univ. of Washington, Seattle,WAUSA

258.2 Minimizing Cutaneous Pain During Electrical 986

Stimulation

John G. Webster, Univ. of Wisconsin, Madison, Wl

USA

258.3 The Effect of Electrode Size On Phase Charge 988

and Its DensityGad Alon, Univ. ofMaryland, Baltimore, MD USA

258.4 Comparison of Commercially Available *

Electrodes from Neuromuscular ElectricalStimulation

Lucinda Baker, Univ. ofSouthern California,

Downey, CA USA

HYPERTHERMIA

Thermal Models

4:30-6 PMSession Chair: T. Samulski

259.1 Heat Transfer and Blood Flow During Hyperther- 990

mla In Normal Canine Brain

Thaddeus V. Samulski, Duke Univ. Medical Center,Durham, NC USA; R.S. Cox, B.E. Lyons, P. Fes-

senden

259.2 A Pretreatment Planning Model for Ferromag- 992

netlc HyperthermiaBhudatt R. Pallwal, Univ. of Wisconsin Hospitalsand Clinics, Madison, Wl USA; G.B. Wang, D.N.

Buechler, R.A. Steeves

259.3 In Vivo Kidneys as Preclinical Thermal Models 994

for HyperthermiaDonald W. DeYoung, Univ. of Arizona, Tucson, AZ

USA; M.A. Kundrat, T.C. Cetas

259.4 Validity of an In Vivo Tissue Model for Hyper- 997

thermla DosimetryPaul R. Stauffer, Univ. of California, San Francisco,CA USA; S.A. Suen, T. Satoh, J.R. Flke, P.K.

Sneed,

259.5 Modeling of SAR Values In Tissue Due to Slab 1000

Loaded Waveguide ApplicatorsMark W, Dewhirst, Duke Univ. Medical Center, Dur¬

ham, NC USA; G. Rine, T.V. Samulski, A. Wallen

259.6 Thermal Response of Ethanol-Flxed Perfused 1002

Kidney Using Microwave RadlometryJonathan B. Leonard, Univ. of Pennsylvania,Philadelphia, PA USA; D.K. Bogen, K.R. Foster

*- manuscriptnot received

IEEE/Ninth Annual Conference of the

Engineering in Medicine and Biology Society

liii

Saturday, November 14 - Afternoon

MEDICAL IMAGING

PET Imaging

1-2:30 PM

Session Chair: E. Mlchell-Tzanakou

230.1 Regional Coupling of Brain Blood Flow and 1004

Neuronal Electrical Activity In Human Visual

Cortex: A Comparison of PET and VEP

Abraham Z. Snyder, Washington Univ. School of

Medicine, St. Louis, MO USA; P.T. Fox, M.E,

Raichle

230.2 Signal Averaging Applied to Positron Emission 1006

TomographyPeter T. Fox, Washington Univ. School of

Medicine, St. Louis, MO USA; M.A. Mlntun, M.E.Raichle

230.3 Brain Regions Activated by the Passive 1008

Processing of Visually and Auditorily Presented

Words Measured by Averaged PET Images of

Blood Flow ChangeSteven E. Petersen, Washington Univ. School of

Medicine, St. Louis, MO USA; P.T. Fox, M.I, Pos-

ner, M.E. Ralohle

230.4 First Experimental Results from a High Spatial 1010

Resolution PET PrototypeAlberto Del Guerra, Univ. of Pisa, Pisa, ITALY; A.

Bandettlni, M. Buoclollnl, M. Contl, G, De Pascalls,P. Maiano, V. Perez-Mendez, C. Rlzzo

Medical Imaging

2:45-4:15 PMSession ChalnS. Wood

247.1 Format Analysis for a Page Reader tor the 1012

Visually ImpairedSally L. Wood, Univ. of Santa Clara, Santa Clara,CAUSA; A, Chekla

247.2 Medical Imaging*

Parvatl Dev, Santa Clam, CA USA

247.3 Automatic Segmentation of Tendon Cross-Sec- 1014

tlon ImagesAmlra Badreldln, General Motors Research

Laboratories, Warren, Ml USA

247.4 Evaluation of a Truly 3D Reconstruction Al- 1016

gorlthm Using 3D Deconvolutlon

Francolse Peyrin, INSA, Villeurbanne, France; R.

Goutte, M. Amiel

247.5 Specific Device for Imaging Breast Tumor 1018

Estrogen ReceptorJacques J. Fonroget, Univ. de Picardle, Amiens,France; J.B, Gullhem, G. Maurel, R. Praca, J. Mul-lle

247.6 Quantitative Analysis of Arteriography Images*

Using PC-Based Imaging SystemVlnay K. Ingle, Northeastern Univ., Boston, MAUSA; D.G. Manolakls, A.L. Kok

MODELING AND

SIMULATION

Physiological Monitoring and Con-

1 - 2:30 PM

Session Chair: R. Allen

231.1 Predictive Monitoring of Intracranial Pressure 1020

Robert Allen, The Univ., Southampton, UK

231.2 Continuous Measurement of Cardiac Output for 1022

the Patients of Surgical OperationHua-Guang Kang, Huazhong Univ. of Science &

Technology, Wuhan, China; A. Lin, H.X. Wu

231.3 Continuous Monitoring of Intro-Arterial Blood 1024

Pressure and ECG During Orthocllnoatatlc Test

Sergio Gandinl, Univ. of Pisa, Neurological Clinic,Pisa, Italy; C. Palombo, C. MarchesI, M. Racltl, 0.

Carpeggianl, S. Tonelll,

231.4 Use of a Computer Aided Design In Phar- 1026

macoklnetlcs for Modellsatlon of Entero-

Hepatlc CycleAlain Segul, Univ. de Rennes I, Rennes, France;E. Percheron, R. Leverge

231.5 Convergence and Robustness of a MMAC Al- 1028

gorlthm for Drug Delivery SystemsHoward Kaufman, Rensselaer Polytechnic Inst.,

Troy, NY USA; W.G. He, X.R. Yu, R. Roy

231.6 Noninvasive Estimation of Cardiac Output 1030

Using a Differential CO: Flck EquationJohn M. Capek, Rensselaer Polytechnic Inst, Troy,NY USA; M. McCormlck, R.J, Roy

liv lEEEVNinth Annual Conference of the

Engineering In Medicine and Biology Society

Saturday,

NEURAL PROSTHESES

Neural Prostheses

2:45-4:15 PM

Session Chair: S. Kovacs, T.S. Kanaka

249.1 Determination of Electrical Characteristics of 1032Neural Tissue In Vivo

Ching-Yen Chang, Massachusetts Inst.of Technol¬

ogy, Cambridge, MA; D.J. Edell

249.2 Design of Two-Dimensional Neural Prosthesis 1034

Mlcroelectrode ArraysGregory T.A. Kovacs, Stanford Univ., Stanford, CAUSA; M.C. Stephankfes, W.R. Knapp, J.P. Mc-

Vittle, J.M. Rosen

249.3 A Piezoelectric Neural Prosthesis to Enhance 1036Nerve RegenerationPatrick Aeblsoher, Brown Univ., Providence, Rl

USA; R.F. Valentlnl, P. Darlo, C, Domenicl, V.

Guenard, S.R, Winn, P.M. Gallettl

249.4 Electro Neuro Prosthesis in Developing Country 1038

T.S. Kanaka, Inst, ofNeurology, Madras, India; G.

Vljaya, M.M. Sampath Kumar

249.5 Selective Stimulation In A Nerve Trunk and Its 1040

Application In UrologyTonsheng Zhang, Xlan Jiaotong Univ., Xian, China;D. Jiang

249.6 Silicon Multichannel Mlcroprobes for Recording 1042

Intracortlcal Single-Unit ActivityKenneth L, Drake, Univ. of Michigan, Ann Arbor, MlUSA; S.L. BeMent, K.D. Wise, J. Farraye

14 - Afternoon

NEUROMUSCULARSYSTEMS

Neuromuscular Systems V

1 -2:30 PM

Session Chair: D. Winter, R. Jones

232.1 On the Tracking Behaviour of Parkinsonian 1044

Patients

SelimS. Hacisalihzade, Swiss Federal Inst, of

Technology (ETH), Zurich, Switzerland; M. Man-

sour, C. Albani

232.2 Sensory-Motor Function Profiles Following 1046

Stroke: Single-Case Graphical AnalysisRichard D. Jones, Christchurch Hospital,Christchurch, NewZealand; I.M. Donaldson, P.J,

Parkin, S.A. Coppage232.3 Phase Relations Among Joint Angle, EMG, and 1048

la Afferent Activity at the Wrist

Allen W. Wlegner, Massachusetts GeneralHospi¬tal, Boston, MA USA; R.R.Young

232.4 Cocontractlon and Coactlvatlon of Muscles 1050

During Human Gait

David A. Winter, Univ. of Waterloo, Waterloo, ONCanada

232.5 Muscular and Joint Force Moments During 1052

Swing In RunningTak K. Cheung, Univ. of Wisconsin, Madison, Wl

USA; E.M. Roberts

232.6 Measurement of Perception Threshold to*

Electric Stimulus In Nervous DysfunctionsMartin Feller, Jr., Clinic of Dlabet.Nutr. & Met. Dis,Bucharest, Romania; Simion Pruna, C. lonescu-

Tirgovi

*- manuscriptnot received

IEEE/Ninth Annual Conference of the

Engineering in Medicine and Biology Society

tv

Saturday, November 14 - Afternoon

PERINATAL MONITORING REHABILITATION

ENGINEERING

Perinatal Monitoring

1 - 2:30 PM

Session Chair: S. Cerutti

233.1 New Approach In Recording Foetal Electrocar- 1054

dlogram and Location of the Foetal Cardiac Vec¬

tor

G. Ravlndran, College of Engineering, Quindy,Madras, India; L.R. Padma

233.2 Integral Function Method - A New Analyzing 1056

Method for Heart Rate VariabilityYasuakl Noguohi, The National Defense Academy,Yokosuka, Japan; H. Hataoka, S. Suglmoto, H,

Kobayashl, M. Kobayashl

233.3 Fetal ECQ Signal Processing from Abdominal 1058

Lead Using Linear Filtering TechniquesSergio Cerutti, Polytechnic Univ., Milano, Italy; G.

Baselli, S. Civardl, G. Fortis, I. Cetln, W. Ferrazzl,G. Pardl

233.4 Automated Processing of Fetal Behaviour 1060Domenloo Ardulnl, Univ. Cattolica S. Cuore, Rome,Italy; Q. Rlzzo, L. Caforio, S. Mancuso, 0.

Romanlni

233.5 Isolation and Analysis of the Human Fetal 1062

Electrocardiographic Waveform In Labour

Henry Murray, Univ. of Nottingham, Nottingham,UK; P.R. Smith, D.L. Kirk, E.M. Symonds

233.6 Fetal ECG Heart Rate Monitor by Adaptive Sys¬tem

Zhou Ll-Gao, Peking, China

Prostheses

2:45-4:15 PMSession Chair: R. Sellktar

256.1 Trunk Placement of Children with and without 1064

Idiopathic Scoliosis Performing Seated Manual

Tasks

Gerald F. Harris, Shriner's Hospital for CrippledChildren, Chicago, IL USA; J.A.A. Miller, D.V.

Mates, J.E. Coad, A.B. SchuKz

256.2 Arm Prosthesis for Above Elbow Amputees 1066

Based on Extended Physiological Propriocep¬tion

Rahamim Sellktar, Drexel Univ., Philadelphia, PAUSA; D.C Baer

266.3 An Integrated System for Muscle Strength Test- 1069

Ing and Exercise

Arthur J. Spaepen, Katholleke Univ. Leuven, Hover-

lee, Belgium M. Wouters, W. Sanson, M. Steyaert

256.4 A New Design of Ligament Prosthesis for 1071Anterior Cruciate Ligament ReplacementJacqueline L. Leandri, Centre de RecherchesChlrurgicales, Cretell, France; Ph. Dahhan, P,

Rey, D. Gelger, O. Tarragano, M. Cerol

256.5 Towards Automatic Design of Custom Leg Pros- 1073theses

Rahamim Sellktar, Drexel Univ., Philadelphia, PAUSA

256.6 A Laryngeal Prosthesis Based on PerilaryngealReflelxes

Loreley Buchholtzer, Dlrectla Sanftara Reg. CFlasi, lasl, Romania; H. Teodoresou, M. Chelaru, L.

Teodorescu

Ivi IEEE/Ninth Annual Conference of the

Engineering in Medicine and Biology Society

Saturday, November 14 - Afternoon

REPRODUCTION MEDICINE

Bioenglneerlng In ReproductionMedicine II

2:45-4:15 PM

Session Chair: S. Guha

255.1 Measurement and Simulation In Reproduction 1075

Research

Sneh Anand, Indian Inst, of Technology, New

Delhi, India

255.2 Sperm Motility Measurement by Two-Angle 1077

Detection of Laser Light ScatteringKap Llm, Univ. of Washington, Seattle, WA USA

W.I. Lee

255.3 ICP Assessment In Neonates Using a New 1079

Anterior FonlanelleTransducer

Jltendra Sharma, Indian Inst, of Technology, New

Delhi, India; S. Anand, S.K. Guha

255.4 A Computer Model for Ovum Transport 1081

Through the Isthmus of the Rabbit Oviduct

M.L. Chatkoff, Univ. of Texas, San Antonio, TX

USA

ROBOTICS

Robotic Force and Touch Sensing

1-2:30 PM

Session Chair: J. Lin

235.1 A Conceptual Framework for Tactually Guided 1083

Exploration and Shape PerceptionH. Hemami, Ohio State Univ., Columbus, OH USA;J.S, Bay, R.E. Goddard

235.2 Study of Range of Motion of Human Fingers: 1085

Application to Anthropomorphic DesignsN.V. Thakor, Johns Hopkins Univ., Baltimore, MD

USA; J.C. Becker

235.3 A Robotic System for Diagnostic Tasks 1087

Paolo Dario, Univ. di Pisa, Pisa, Italy; M, Ber-

gamasco, A. Sabatini, A. Vaccarelli

236.4 Electrochemlcally Driven Muscle-Like Actuators 1089

Danllo De Rossi, Univ. di Pisa, Pisa, Italy; P.

Chiarelli, G. Genulni

235.5 Miniature Electrooptlcal Force Transducer 1092

John G. Webster, Univ. of Wisconsin, Madison, Wl

USA; N. Maalej

Robotics

2:45-4:15 PM

Session Chair: J.G. Webster, P. Rabischong

250.1 Sensors in Prosthetic Systems for Computer 1094

Controlled WalkingWen H. Ko, Case Western Reserve Univ.,Cleveland, OH USA; Theresa CL. Mlao Spear,Alex Massiello, Thomas M. Spear

250.2 A Robot In an Operating Room: A Bull In a 1096

China Shop?John M. Dolan, Carnegie-Mellon Univ., Pittsburgh,PA USA; M.B, Friedman, M.L. Nagurka, J.K.

Gotow

250.3 CAD - System for a Magnetically Actuated Artitl- 1098

clal Heart

Stephen G. Kovacs, Univ. of South Florida, Tampa,

FL USA; M.S. Sweeney, L.E. Ondrovic

250.4 A Mobile Robotic System as an Aid for the 1100

Severely HandicappedJohn B. Cheatham, Rice Univ., Houston, TX USA;M.A. Regalbuto, T.A. Krouskop, D.J. Winningham

250.5 Robotic Ophthalmic Surgery - An Evaluation In 1102

Radial KeratotomyStephen N. Levy, Mount Sinai Medical Center, Nor-

walk, CTUSA; K. Ramani

250.6 Robotized Scanning Laser Handpiece for Der- 1104

matologySerge R. Mordon, INSERM U.279, Lille, France;G. Rotteleur, B. Buys, J.P. Sozanskl, J.M.

Brunetaud, Y. Moschetto

*- manuscript IEEE/Ninth Annual Conference of the Ivii

not received Engineering in Medicine and Biology Society

Saturday, November 14 - Afternoon

vLCtr

Sleep and Respiration

4:30-6 PM

Session Chair: A, Cornwell

266.1 In Fetal Breathing Movements*

Hazel H. Szeto, Cornell Univ. Medical College,NewYork.NYUSA; J.G. Dwyer

266.2 Sleep Respiratory Behavior In Normal Term and 1106

Preterm Infants: Implications for Sudden Infant

Death Syndrome (SIDS)Toke Hoppenbrouwers, LAC/USC Medical Center,

Los Angeles, CA USA; J.E, Hodgman,

266.3 A Nonlinear Model Study of Periodic Breathing 1108

In Infants

SherwInT. Nugent, Dalhousie Univ., Halifax, NS,

Canada; Q.A. Tan, J.P. Flnley

266.4 Sleep Apnea In "Near Miss" and Control Infants 1111

Anne Chrlstake Cornwell, Flushing Hospital andMedical Center, Flushing, NY USA; S. Lax-

mlnarayan

266.6 Regional Cerebral Blood Flow Response to 1113

Apnea In Newborn Piglets: Energy Metabolism

and Membrane Function

Jan M. Goplerud, Univ. of Pennsylvania, Philadel¬

phia, PA USA; L.C. Wagerle, O.P. Mlshra, M.

Delfvorla-Papadopoulos

266.6 Clinical Need to Identify Zones of Vulnerability 1117

of the LungEmlle M. Scarpelll, Schneider Children's Hospital of

Long Island Jewish Medical Center, New HydePark, NY USA

TECHNOLOGICAL ADVAN¬

CES IN MODELS FOR

BIOMEDICAL RESEARCH

Technological Advances In Models for

Biomedical Research Symposium

000.1 Mathematical Models In Physiology 1120

Charles S. Peskin, New York Univ., New York, NY

USA; D.M. McQueen, A.L. Fogelson, D.

Tranchlna, H.M. Lacker, R.M. Novlck

000.2 Building Mathematical Models from Experimen-*

tal Data

Gary Blau,

000.3 Physical Models of Hemodynamic Systems 1123

Robert J. Lutz, NIH Division of Research Services,

Bethesda, MD USA

000.4 In Vitro Models for the Evaluation of Toxicity 1126

and CarcinogenesisAlan M. Goldberg, Johns Hopkins School of Public

Health, Baltimore, MD USA

000.6 Appropriateness of Study Size In Animal Car- 1127

clnogenlcHy ExperimentsChristopher J, Portler, National Inst of Environmen¬

tal Health Sciences, Research Triangle Pk, NC

USA; D.G.Hoel

Animal Experimentation and the

Engineer's Responsibilities

001.1 Panel Discussion

J. Burrls, Moderator; M. Armstrong, W,J. Dodds,M. Eden, R.D, Hunt, N.L, Levin, H. Splra

Iviif IEEE/Ninth Annual Conference of the

Engineering In Medicine and Biology Society


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