Conference Proceedings
26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
EMBC
2004
LINKAGES FOR INNOVATION
IN 81O ML DICi NE
SAN FRANCISCO, USA
1-5 September 2004
San Francisco, California
Volume V
Conference Chair Program Chair Publications Chair
Donna Hudson, Ph.D. Zhi-Pei Liang, Ph.D. Guy Dumont, Ph.D.
A Novel Mobile Telemedicine SystemforAmbulance Transport, Design andEvaluationMandellos, G. J.; Lymberopoulos, D. K.; Koukias,M. N.; Tzes, A.; Lazarou, N.; Vagianos, C. 3080
Using Telehealth Technology to Improve the
Delivery ofHealth Services to People who are
Deaf
Hughes, Glen; Hudgins, Bernard; MacDougall,James 3084
Networking Technology andHealth Care in
Eastern North Carolina
Brinn, JackE. 3088
Establishing a Rural Telehealth Project: the
WyomingNetworkfor Telehealth
Gantenbein, Rex E.; Cadez, Fran; Stamm, BethHudnall 3089
Session 7.1.2: Telemedicine Technologyand Deployment II
Design ofan Interoperability Framework in a
Regional Healthcare SystemBerler, Alexander A.; Pavlopoulos, Sotiris;Koutsouris, Dimitris
ntegration ofMonitoring Devices in thee-Vital
Service
Jakka, Eleni; Prentza, Andriana; Lamprinos, Ilias
E.; Leondaridis, Lefteris; Koutsouris, Dimitris
Bio~Stream: A System Architecturefor Real-
Time Processing ofPhysiological SignalsBar-Or, Amir; Goddeau, David M.; Healey,Jennifer A.; Kontothanassis, Leonidas; Logan,Beth;Nelson, Alex; Van Thong, Jean-Manuel
UsingHandheldDevicesfor Real-Time Wireless
Teleconsultation
Banitsas, Konstantinos A.; Georgiadis, P,;Tachakra, S.; Cavouras, D.
Design ofMultimedia Telemedicine SystemforInter-hospital ConsultationSun K. Yoo, Kwang M. Kim, Suck M. Jung,Kyung Joung Lee, Nam H. Kim
TM-Provider: a New Communicatory ModelforTelemedicine Services SupportKolovou, Lamprini T.; Triantafyllou, George N.;Chassomeris, Constantine A.;Karavatselou, Evy I.; Lymberopoulos, Dimitris K.
A Front-end Platform ofthe Network-based
Intelligent Home Healthcare Embedded SystemTang, Shuo; Chan, Weng Chi; Vai, Mang I.; Mak,
Peng Un
3093
3097
3101
3105
3109
3112
3116
Track 7.2: Virtual and AugmentedReality Technology in Healthcare
Session 7.2.1: Telesurgery and Virtual
Reality Technology in Healthcare I
Modeling Liver Physiology: Combining Fractals,Imaging andAnimationLin, Debbie 3120
Virtual Planning ofMulticatheter BrachytherapyImplants for Accelerated Partial
Breast Irradiation
Schmidt-Ullrich, P. N.; Todor, D. A.; Cuttino, L.W.; Arthur, D. W. 3124
Linking Ontologies with Three-Dimensional
Models ofAnatomy to Predict the Effects ofPenetrating InjuriesRubin, Daniel L.; Bashir, Yasser; Grossman,David; Dev, Parvati; Musen, Mark A. 3128
A NovelNavigation Principle in Computer-Assisted SurgeryBuzug, Thorsten M.; Hering, Peter; Bongartz,Jens; Ivanenko, Michael 3132
Session 7.2.2: Telesurgery and Virtual
Reality Technology in Healthcare II
Content-Based Video Codingfor Remote
Monitoring ofNeurosurgeryXu, Jian; Ilgin, Hakki; Liu, Qiang; Kassam, Amin;Sclabassi, Robert J.; Chaparro, Luis F.; Sun,Mingui 3136
Networked Interaction Therapy: Relieving Stress
in Memory-Impaired People and Their
Family MembersKuwahara, Noriaki; Kuwabara, Kazuhiro; Utsumi,Akira; Yasuda, Kiyoshi; Tetsutani, Nobuji 3140
Identification ofLenke Spine DeformityClassification By Simplified 3D Spine ModelLin, Hong; Sucato, Dan 3144
Track 7.4: Electronic Health Records
and Medical Databases
Session 7.4.1: Electronic Health Records
and Medical Databases I
Personal Recognition using Head-Top Imagefor
Health-Monitoring System in the Home
Nakajima, Kazuki; Sasaki, Kazuo 3147
A Home Health Monitoring System Including
Intelligent Reporting andAlerts
Garsden, Hugh; Basilakis, Jim; Celler, Branko G.;Huynh, Khang; Lovell, Nigel H. 3151
xl
An Extensible FrameworkforSharing Clinical
Guidelines and Services
Xiong, Fei; Cao, Kefei; Wang, Zhifeng; Ford,James; Pearlman, J. D.; Makedon, F. S. 3155
Application and Evaluation ofPersonal HealthInformation Management SystemKim, Eung-Hun; Wang, Maisie; Lau, Christopher;Kim, Yongmin 3159
Towards Total Knowledge ManagementforHealthcare: Clinical and OrganizationalConsiderations
Baskaran, Vikram; Bali, Rajeev K.; Arochena,Hisbel; Naguib, RaoufN. G.;Dwivedi, Ashish N.; Nassar, Nahy S. 3163
Session 7.4.2: Electronic Health Records
and Medical Databases II
An IndexedAtlasfor Content-basedRetrieval
andAnalysis ofMammogramsLau, Howard; Mok, Kelvin; So, Donald; Tse,Courtney; Rangayyan, Rangaraj M. 3167
The Knowledge Management Landscape:
Implicationsfor Clinical KnowledgeManagementandPractice
Dwivedi, Ashish R; Bali, Rajeev K.; Naguib,RaoufN. G.; Nassar, Nahy S.
Declarative Algebra and Continuous QueryLanguagefor Biomedical Stream Processing in
Fetal Monitoring SystemWrobel, Janusz; Widera, Michal; Horoba,
Krzysztof; Jezewski, Janusz; Winiarczyk, Ryszard
A DatabseApplication to Manage Patients'Data
with a Cochlear ImplantatZhou, Guohong
Track 7.5: Machine Learning and
Clinical Decision Support
Session 7.5.1: Machine Learning andClinical Decision Support I
Transitional Appearance-BasedMotion Tracking
for Real-Time Breast
Self-Examination SupervisionHu, Yuqin; Naguib, RaoufN. G.; Todman Alison
G.; Aram, Saad A.; Al-Omishy, Hassanein
Support Vector Machinefor DeterminingDose of
DialysisRay, Monika; Array, Naveen
Computer Aided Interactive Remote Diagnosis
Using Self-Organizing MapsVbros, Tibor; Laczk6, Jozsef; Keresztenyi, Zoltan;
Fazekas, Csaba
3171
3175
3179
3182
3186
3190
Classification ofLungData bySampling andSupport VectorMachine
Dehmeshki, Jamshid; Chen, Jun; Casique, ManlioValdivieso; Karakoy, Mustafa
An Input Classification Schemefor Use in
Evidence-Based Dynamic Recurrent
Neuro-Fuzzy PrognosisWang, Yu; Winters, Jack M.
Predicting Clinical Outcomesfor Newborns
using Two Artificial Intelligence ApproachesFrize, Monique; Ibrahim, Doaa; Seker, Husvein;Walker, Robin C;
Odetayo, Michael 0.; Naguib, RaoufN. G.
A New Melanoma Diagnosis Active SupportSystemFiorini, Rodolfo A.; Dacquino, G.; Laguteta, G.
Session 7.5.2: Machine Learning andClinical Decision Support II
Estimating the Efficiency ofMedicalDiagnosticSystemsLehocki, Fedor; Pis, Pavel; Kukucka, Marek
Creating a TextData-Mining Applicationfor Use
in Public Health InformaticsMichel, Martha
SAGEDesktop: An Environmentfor TestingClinical Practice Guidelines
Berg, David; Ram, Prabhu; Glasgow, Julie; Castro,
Jonathan
HandMotion Segmentation AgainstSkin Co/our
Background in BreastAwareness ApplicationsHu, Yuqin; Naguib, RaoufN. G.; Todman, Alison
G.; Amin, Saad A.; Oikonomou, Andreas;
Al-Omishy, Hassanein; Tucker, Nick
MedicalDecision Support SystemforDiagnosisofSoft Tissue Tumors Basedon
DistributedArchitecture
Garcia-Gomez, Juan M.; Vidal, Cesar, Vicente,
Javier; Marti-Bonmati, Luis; Robles, Montserrat
Hereditary Non-Polyposis Colorectal Cancer
RiskAssessmentBased on AIAnalysis of
Pedigree Data
Kokuer, Munewer; Naguib, RaoufN. G.;
Jancovic, Peter; Younghusband, H. Banfield;
Green, Roger
3194
3198
3202
3206
3210
3214
3217
3221
3225
3229
xli
Track 7.6: PACS, Data Compression,
Storage, Retrieval, Communication
and Security
Session 7.6.1: PACS, Storage, Retrieval
and Watermarking
Tracing Medical Images Using Multi-Band
Watermarks
Li, Mingyan; Narayanan, Sreeram; Poovendran,Radha 3233
Reversible WatermarkingforAuthentication of
DICOMImagesZain, Jasni M.; Clarke, Malcolm; Baldwin, LynneP. 3237
A Multiple Watermarking Scheme Applied to
Medical Image ManagementGiakoumaki, Aggeliki; Pavlopoulos, Sotiris;
Koutsouris, Dimitris 3241
Wavelet Coding of Volumetric MedicalImageswith High Throughput and OperabilityWu, Xiaolin; Qiu, Tong 3245
Efficient Similarity Retrievalfor Temporal Shape
Sequences: A Case Study using Cardiac
MR ImagesHuang, Heng; Makedon, Fillia; Ford, James; Shen,Li; Wang, Yuhang; Steinberg, Tilmann;
Gao, Ling; Pearlman, Justin 3250
HbRASCH - A Programming FrameworkforTransparent Access to Physiological SignalsSchneider, Raphael; Bauer; Axel; Barthel, Petra;
Schmidt, Georg 3254
Track 7.7: Emerging IT for
Efficient/Low-Cost Healthcare Delivery
Session 7.7.1: Emerging IT for Efficient,Low-Cost Healthcare Delivery
Low-Bandwidth TelephonyforAccess to NursingServicesfor Stroke Sun'ivors and
Their CaregiversTran.BinhQ. 3258
A Mobile-Phone Based Telecare Systemfor the
ElderlyTamura, Toshiyo 3260
Home Health and Home Monitoring in Rural
and Frontier Counties: Human Factors
in ImplementationWeeg, Stephen C. 3264
VTAMN-A Smart ClotheforAmbulatoryRemote Monitoring ofPhysiological Parameters
and ActivityNoury, N. M.; Dittmar, A.; Corroy, C; Baghai, R.;Weber, J. L.; Blanc, D.; Klefstat, F.; Blinovska,A.;Vaysse, S.; Comet, B. 3266
Reconfigurable Point-of-Care Systems Designedwith Interoperability Standards
Warren, Steve; Yao, Jianchu; Schmitz, Ryan;
Lebak, Jeff 3270
Status ofMobile Computing in Health Care: An
Evidence StudyGollol Raju, Narasimha S.; Anthony, James P.;
Jamadagni, Radhakrishna $.; Laxminarayan, S.;
Suri, J.; Istepanian, R. 3274
Session 7.7.2: Emerging IT in Healthcare I
A Wearable Devicefor a Fully Automated In-
Hospital Staff and Patient IdentificationCavalleri, M.; Morstabilini, R.; Reni, G. 3278
A Mobile Teletrauma Systemfor Rural Trauma
Care
Chu, Yuechun; Ganz, Aura 3282
Design Considerations and Implementation ofa
Cost-Effective, Portable Remote Monitoring Unit
Using 3G Wireless Data Networks
Gupta, Shashank; Ganz, Aura 3286
DI(g)L-hg BY DESIGN: ANINTEGRATED
TELE-CARE COMMVNICAHON
INFRASTRUCTURE
Black, Lesley-Ann; McTear, Mike F.; Black,Norman D.; Harper, Roy; Lemon, Michelle 3290
The Potential ofa Store and Forward Tele-
Behavioral Platformfor Effective Treatment and
Research ofAutism
Oberleilner, Ronald M.; Laxminarayan, Swamy;Suri, Jasjit 3294
A Low-Cost Frameworkfor Individualized
Interactive Teterehahllitatlon
Jadhav, Chetan; Krovi, Venkat 3297
Wearable Devicesfor Emerging Healthcare
ApplicationsScheffler, Michael; Hirt, Ktienne 3301
Session 7.7.3: Emerging IT In Healthcare
It
ACTIDOM-A MicroSystem based on MEMSforActivity Monitoring ofthe Frail Elderly in their
Daily LifeNorbert. N M ; Rarralon, P
,Couturier, P .
Favre-
Reguillon, F.Guillcnmud. R
,Mesial"., I*; Caritu,
Y.;
xlii
David, D.; Moine, S.; Franco, A.; Guiraud-By, F.;Berenguer, M.; Provost, H. 3305
Realization ofan e-Health System to Perceive
Emergency Situations
Shin, S. C; Ryu, C. Y.; Kang, J. H.; Nam, S. H.;Song, Y. S.; Lim, T. G; Lee, J. W.; Park, D. G.;Kim,S.H.;Kim,Y.T. 3309
A Communication Platformfor DiabetesSurveillance
Tang, Shih-Tsang 3313
A Mobile Phone-BasedSafety Support SystemforWandering Elderly Persons
Ogawa, Hidekuni; Yonezawa, Yoshiharu; Maki,Hiromichi; Sato, Haruhiko; Caldwell, W, Morton 3316
Design ofa Wearable Devicefor ECGContinuous Monitoring Using Wireless
TechnologyLed, Santiago; Fernandez, Jorge; Serrano, Luis 3318
SCIENT- Smart Configurable InfrastructureforNext-Generation TeleMonitoringGupta, Shashank; Ganz, Aura 3322
Track 7.8: Web-Based Medical
Information Systems
Session 7.8.1: Medical Information
Systems I
Java-BasedBrowsing, Visualization and
Processing ofHeterogeneous MedicalDatafromRemote RepositoriesMasseroli, Marco; Bonacina, Stefano; Pinciroli,Francesco 3326
Design ofa Web-BasedHealth Promotion SystemandIts PracticalImplementationfor CycleErgometer Exercise
Wang, Zhihui; Kiryu, Tohru 3330
Towards a Web Senices InfrastructureforPerinatal, Obstetrical, and Neonatal Clinical
Decision SupportCatley, Christina; Frize, Monique; Petriu, Dorina
C; Walker, C.Robin; Yang, Lan 3334
HL 7-Compliant Healthcare Information Systemfor Home MonitoringLebak, Jeffrey W.; Yao, Jianchu; Warren, Steve 3338
"On-demand" Access to a Multi-PurposeCollection ofBest Practice Standards
Del Fiol, Guilherme; Rocha, Roberto A.;
Washburn, Jeffrey; Rhodes, Julie; Hulse, Nathan
C;Bradshaw, Richard L.; Roemer, Lorrie K. 3342
Integrating Clinical Trial Datafor Decision
Making via Web Senices
Jiang, Keyuan 3346
Session 7.8.2: Medical Information
Systems II
The Knowledge Authoring Tool: An XML-based
Knowledge Acquisition Environment
Hulse, Nathan C.; Rocha, Roberto A,; Del Fiol,Guilherme; Bradshaw, Richard L.;Hanna, Timothy P.; Roemer, Lorrie K. 3350
Application ofHLlin a Collaborative Healthcare
Information SystemCheng, Po-Hsun; Yang, Chou-Han; Chen, Heng-Shuen; Chen, Sao-Jie; Lai, Jin-Shin 3354
Teleconsultations Using Content-Based Retrieval
ofParametric ImagesRuminski, Jacek 3358
Track 7.9: Mobile Health
Session 7.9.1: Mobile Telehealth and
Wireless Patient Monitoring
A Systemfor Ubiquitous Health Monitoring in
the Bedroom via a Bluetooth Network and
Wireless LAN
Choi, Jong Min; Choi, Byung Hun; Seo, Jin Woo;Sohn, Ryang Hee; Ryu, Myung Suk;Yi, WonJin; Park, Kwang Suk 3362
Multi-Channel Measurement ofPhoto-
Plethysmography andEvaluationfor the OptimalSite ofa Thigh in a Toilet
Kim, Jungsoo; Park, Juwan; Ryu, MyungSuk;Park, Kwangsuk 3366
Development of "MobileAudiometer"forScreening using Mobile Phones
Nakamura, Norio 3369
Experiences Using WinCEPocketPCs as
Computation andData Acquisition Platformsfor
Ambulatory TelemonitoringNagl, Luke J.; Krishnamurthi, Balakumar;
Schoenig, Scott; Warren, Steve; Andresen, Dan 3373
Use ofM3Sfor Mobile/Local Controls Over a
Remote/Fixed Environment
Chang, Yi-Chu 3377
A Novel Communications Networkfor the
Provision ofMedical Care in Disaster and
Emergency Situations
Dembeyiotis, Spiro; Konnis, Georgios J.;Koutsouris, Dimitris 3380
Development of Wireless Blood Glucose Meter
and Diabetes Self-Management SystemChen,You-Yin 3384
Mobile Telemedicine Systemfor Home Care and
Patient MonitoringFigueredo, Marcus V. M.; Dias, JoSo S, 3387
xliii
Theme 8. Clinical Engineering
Track 8.1: Clinical Applications for
Telemedicine
Session 8.1.1: Clinical Applications for
Telemedicine
Telellealth - Operational Issues to Consider
David, Yadin 3391
The Telemedicine and Teleconsultation System
Application in Clinical Medicine
Chang, Tzyh-Chyang; Lee, Jiann-Der; Wu, Shwu-
Jiuan 3392
Transmission ofDigital Electrocardiogram
(ECG) via Modem Connection in Southern BrazilRussomano, Thais; Sparenberg, Adolfo L. F;Azevedo, Dario F. G. de 3396
An Image-BasedAnalysisfor ClassifyingMultimodal Brain Images in the Image-GuidedMedical Diagnosis Model
Lau, Phooi Yee; Ozawa, Shinji 3400
An Open Strategyfor Implementing PACS and
Its Primary ApplicationTiquan, Liu; Siping, Chen; Jingyi, Feng; Duan,Huilong 3404
Track 8.2: Medical
Operations/Decision Support Systems
Session 8.2.1: Medical
Operations/Decision Support Systems
Engineering Managed Care Automation via the
Treatment Planning Process: A
Bottom-up ApproachHanna, Darrin 3408
Remote Expert System ofSupport the Prostate
Cancer DiagnosisPereira, Marcos A.; Schaefer, Marcela B.;Marques, Jefferson L, B. 3412
DESSA: A New Decision Support SystemforNeurosurgeryDimopoulos, K. G.; Baltogtannis, C; Scorila, E.;Kimonides, V. G.; Sakas, D.; Lymberopoulos, D.
K. 3416
Towards Ethical Decision Support andKnowledge Management in Neonatal Care
Yang, Lan; Frize, Monique; Walker, C. Robin;Catley, Christina 3420
Automatic 3D I 'oscular Tree Cons/ruction ofPerforator Flapsfor Plastic Surgery PlanningGao, Jean; Wen, Quari
"
3424
Damper Designfor Improving S/NRatio ofthe
Seistnocardiogram Monitoring in the OpenMRI-guided Operating Theater
Naemura, Kiyoshi; Iseki, Hiroshi 3428
Using The Full Scale 3D Solid AnthropometricModel in Radiation Oncology Positioningand VerificationSun, Shuh-Ping; Wu, Ching-Jung 3432
Track 8.3: Critical-Care and IntelligentMonitoring Systems
Session 8.3.1: Critical-Care and IntelligentMonitoring Systems
Determining Critical Values of CalculatedParameters Within a Physiologic ModelHutchinson, George
A Wireless ECG Smart Sensorfor Broad
Application in Life Threatening Event DetectionWelch, James P,; Guilak, Farzin; Baker, Steve
Mobile Medical Device Connectivity in the
Hospital EnvironmentPelt us, Dan C.
3436
Development ofan Implantable Intrathecal DrugInfusion PumpHong, Soyoung; Lee, Jung Seok; Park, Jim Woo;Nam, Kyoungwon; Choi, Jaesoon; Lee, JungChan;Park Chan Young; Ko, Young Pil; Jo, Young Ho 3440
The Shape ofElectrical Impedance Spectroscopy(EIS) is Altered in Stroke Patients
Bonmassar, Giorgio; Iwaki, Sunao 3443
3447
3450
End Tidal Carbon Dioxide Measurement Usingan Electro Acoustic Sensor
Foike, Mia K.; Hftk.Bertil; Kkstrfim, Mikael;Backlund, Ylva 3452
Estimation ofBeat-to-Beat Systolic BloodPressure Using Pulse Arrive Time and Pulse
Width Derivedfrom the PhotoplethysmogramLin, Yuan-Hsiang; Ko, Patrick Chow-In; Wang,Hsiang-Yao; Lu, Tsung-C'hien; Chen, Yen-Yu;Jan, I-Chicn; Jan, Gwo-Jcn; Chou, Nai-Kuan 3456
Automated Agitation Management Accountingfor Saturation DynamicsRudge, Andrew D.; Chase, J, Geoffrey, Shaw,
Geoffrey M.; l.ee, Dominic 3459
xliv
Session 8.3.2: Critical Care & IntelligentMonitoring
Adaptive Bolus-Based Set-PointRegulation ofHyperglycemia in Critical Care
Lin, Jessica; Chase, J. G; Shaw, G. M.; Doran, C.
V.; Hann, C. E.; Robertson, M. B.; Browne, P. M.;Lotz, T.; Wake, G. C; Broughton, B. 3463
Construction ofa Conformal Water Bolus Vest
Applicatorfor Hyperthermia Treatment ofSuperficial Skin Cancer
Juang, Titania; Neuman, Daniel; Schlorff, Jaime;Stauffer, Paul R. 3467
Track 8.4: Technology Assessmentand Management
Session 8.4.1: Technology Assessmentand Management
A TechnologyRoadmapfor Rehabilitation
EngineeringPrice, Sheila; Summers, Ron 3471
Automatic Characterization ofEvents on Sp02Signal: Comparison of Two MethodsChambrin, Marie-Christine; Charbonnier, Sylvie;Sharshar, Samir; Becq, Guillaume; Badji, Lyes 3474
Neural Networksfor Predicting TechnologicalUse in Neonatal Care
Scalon, Joao D. 3478
Application ofSpectral Entropy to EEG and
Facial EMG Frequency Bandsfor theAssessment ofLevel ofSedation in ICU
Rautee, Riina; Sampson, Timothy; Sarkela, Mika;Melfo, Sari; Hovilehto, Seppo; van Gils, Mark 3481
Evalutate Alternative Service ContractsforMedical EquipmentDe Vivo, Liliana; Derrico, Pietro; Tomaiuolo,Daniela; Capussotto, Carlo; Reali, Alfredo 3485
Targeting Shock Waves in Human Tissuefor
Extracorporeal Shock Wave TherapyManousakas, loannis; Wan, Long-Ray; Liang,Shen-Min 3489
Track 8.5: Ethics, Standardization,Policy, Cost and Safety
Session 8.5.1: Ethics, Standardization,
Policy, Cost and Safety
Applications ofthe PetriNet to Simulate, Test,and Validate the Performance and Safety of
Complex, Heterogeneous, Multi-Modality Patient
Monitoring Alarm SystemsSloane, Elliot B.; Gelhot, Vijay 3492
Failure Mode EffectAnalysis Applied to the Use
ofInfusion PumpsFechter, Richard J.; Barba, Julio J. 3496
Improving A Health Care System Following AnIncident InvestigationShepherd, Marvin 3500
The Square Peg and theRoundHole: Murphy'sLaw and Medical Device Connections
Baretich, Matthew F. 3503
Risk Assessment - Hospital View in SelectingMedical TechnologiesDavid, Yadin 3504
Session 8.5.2: Medical TechnologyStandardization, Policy, Cost and Risk
A Thirty-Two Year Perspective on a Clinical
Engineer's Contributions to Patient SafetyHyndman, Bruce H. 3505
Cost Management ofMedical EquipmentMaintenance
Rocha, Leticia S.; Bassani, Jose W. M. 3508
Medical Device SecurityGrimes, Stephen L. 3512
Electromagnetic Interference To Infusion PumpsFrom GSMMobilePhones
Calcagnini, Giovanni; Bartolini, Pietro; Floris,Matteo; Triventi, Michele; Cianfanelli, Plinio;Scavino, G.; Proietti, L.; Barbara, Vincenzo 3515
Benchmarking Clinical Engineering ProgramDavid, Yadin 3519
Theme 9. Drug Delivery and Gene
Therapy
Track 9.1: Novel Carriers for Drug and
Gene Delivery
Session 9.1.1: Drug and Gene Delivery I
DirectedEvolution ofAA VMutantsforEnhanced Gene DeliverySchaffer, David V.; Maheshri, Narendra
Systemic Virus Dissemination duringLocal Gene
Delivery in Solid Tumors
Wang, Yong; Li, Chuan-Yuan; Yuan, Fan
Ultrasound Enhancement ofDrug Release
Across Non Ionic Surfactant Vesicle Membranes
Hood, Elizabeth; Gonzalez, Monica; Strom, Joel;VanAuker, Michael
3520
3524
3527
xlv
Sonoporation ofCellsfor Drug and Gene
DeliveryPan, H.; Zhou, Y.; Sieling, F.; Shi, J.; Cui, J.;
Deng, Cheri
Applying Models of Targeted Drug Delivery to
Gene DeliveryLam, Tai Ning; Hunt, C. Anthony
Quantitative Description and Model ofMolecule
Transport through Skin
Bao, Jiali; Wang, Hong; Wang, Huiping; Ge,
Jiguang
Track 9.2: Facilitated Transport of
Drugs and Genes
Session 9.2.1: Drug and Gene Delivery II
Investigations ofNeedle-free Jet InjectionsBaxter, Joy R.; Mitragotri, Samir
3531
3535
3539
The Development ofNovel Flexible Electrode
Arraysfor the Electrochemotherapy ofSolid
Tumour Tissue (Potentialfor EndoscopicTreatment ofInaccessible Cancers)Soden, Declan M.; Larkin, John; Collins,Christopher; Aarons, Simon; Piggott, John;
Morrissey, Anthony; Norman, Aaron; Dunne,:olum; O'Sullivan, Gerald C.
Sequential Finite Element Model of Tissue
llectropermeabilisationdiklavcic, Damijan; Sel, Davorka; Cukjati, David;latiuskaire, Danute; Slivnik, Tomaz; Mir, Lluis
A.
Theme 10. Cardiovascular and
Pulmonary Systems
Track 10.1: Electrocardiology
Session 10.1.1: Bioelectric and
Biomechanical Forward and Inverse
Problems
Using Models of the Passive Cardiac
Conductivity and Full Heart AnisotropicBldomain to Study the Epicardial Potentials in
Ischemia
Stinstra, Jeroen G.; Hopenfeld, Bruce; MacLeod,RobS.
ECGSIM: an Interactive Toolfor the Study ofthe Relation BetH'een the Electric Activity oftheHeart and the QRST Waveforms at the BodySurface
Oostendorp, Thorn I\; van Oosterom. Adriaan
3543
3547
3551
3555
3559
Forward Modeling of Ventricular
Electromechanical Interactions: Normal and
Failing Hearts
Usyk, Taras P.; McCulIoch, Andrew D. 3553
Inverse Electrocardiography in the Framework
ofDynamic Imaging Problems
Brooks, Dana H.; Ghodrati, Alireza; Zhang,Yiheng; Tadmor, Gilead; MacLeod, Robert S. 3555
The Influence of Volume Conduction Effects onthe EEG/MEG Reconstruction ofthe Sources ofthe Early Left Anterior NegativityWolters, Carsten H.; Amvander, Alfred; Maess,Burkhard; MacLeod, Rob S.; Friederici, AngelaD. 3569
Electrical Impedance ImagingIsaacson, David 3573
Session 10.1.2: Cardiac Activation
Mapping and Wall Mlcrostructure
Optical Mapping Systemfor Recording Action
Potential Durations in Adult Mouse Left and
Right Atrium
Nygren, Anders; Lomax, Alan K.; Giles, WayneR. 3576
High Resolution Optical Mapping ofCardiacAction Potentials in Freely Beating Rabbit
Hearts
Inagaki, Masashi; Hidaka, Ichiro; Aiba, Takeshi;Tatewaki, Teiji; Sunagawa, Kenji; Sugimachi,Masaru
"
3578
Siimulations of Optical Mapping DuringElectroporattonJanks, Deborah L,; Roth, Bradley J. 3581
A Study of the Dynamics of Cardiac Ischemia
using Experimental and Modeling ApproachesShome, Shibaji; Stinstra, Jeroen G.; Hopenfeld,Bruce; Punske, Bonnie B.; Maeleod, Rob S. 3585
Constructing a Tissue-Specific Model ofVentricular Mlcrostructure
Sands, Gregory; Trew, Mark; I looks, Darren; Le
Grice, Ian; Pullan, Andrew; Smaill. Bruce 3589
Conduction Velocit}' in Myocardium Modulated
by Strain: Measurement Instrumentation
and Initial Results
Sachse, F. B.; Steadman, B W,; Bridge, J, H. B.;Punske, B. B.; Taceardi. ». 3593
Session 10.1.3: Electro and
Magnetocardfology and Cardiac
Arrhythmia AnalysisECG QRS Complex Detection I "sing SlopeVector Waveform (SVW) AlgorithmXu, Xiaomin; l.iu, Yimj 3597
xlvi
ComparingRegularizedB-splineNeural
Network, Multilayer Perceptron andBoosted-CARTon Two Problems ofHeart ArrhythmiaDiagnosisZhou, Jie 3601
Analysis ofBeat-To-Beat Variability ofVentricular Late Potentials by a Spectro-Temporal Technique in Patients with Chagas'Disease
Laciar, Eric; Jane\ Raimon 3605
Monitoring Fetal Development with
MagnetocardiographyPadhye, Nikhil S.; Brazdeikis, A.; Verklan, M. T. 3609
Physiologic Responses to Acupuncture Point
Stimulation: A Pilot Study to Evaluate Methods
and Instrumentation
Tsunami, Daniel T.; Colbert, Agatha; Lu,
Zhaoxue; Pearson, Sean;McNames, James; Hammerschlag, Richard 3611
Session 10.1.4: Molecular Cardiology
Electrocardiographic Characterization ofEmbryonic ZebrafishForouhar, Arian S,; Hove, Jay R.; Calvert,Christopher; Flores, Jorge; Jadvar, Hossein;Gharib, Morteza 3615
IL-2 Confers Cardioprotection by InhibitingMitochondrial Permeability Transition Pore
Cao, Chun-Mei; Chen, Jun-Zhu; Xia, Qiang;
Zhang, Shi-Zhong; Lin, Guo-Hua; Wong, Tak-
Ming 3618
Role ofthe Mitochondrial PermeabilityTransition Pore in TNF-AIpha-Jnduced Recovery
ofVentricular Contraction andReduction of
Infarct Size in IsolatedRat Hearts Subjected to
Ischemia/ReperfusionGao, Qin; Xia, Qiang; Cao, Chun-Mei; Zhang,
Shi-Zhong; Bruce, Iain C. 3622
The Mitochondrial Calcium Uniporter
Participates in Ischemia/Reperfusion Injur}' and
in Cardioprotection by Ischemic Preconditioning
Zhang, Shi-Zhong; Xia, Qiang; Cao, Chun-Mei;
Gao, Qin; Bruce, Iain C. 3625
Effects ofInterleukin-2 on theMechanical
Restitution andPost-Rest Contraction in Rat
Ventricular Papillary Muscle
Lin, Guo-Hua; Ru, Hai-Long; Wu, Pei-Lin; Cao,
Chun-Mei; Xia, Qiang 3628
Negative Inotropic Effect ofInterleukin-2 in the
Isolated Ventricular Myocytes: Role ofNitric
Oxide/sGC Pathway
Wang, Hui-Ping; Xia, Qiang; Jin, Hong-Feng;
Cao, Chun-Mei; Lin, Guo-Hua 3632
Track 10.2: Ventricular Mechanics
Session 10.2.1: Cardiac Mechanics:
Systolic and Diastolic Functions
Hemodynamic Interventions and the Pressure-
Diameter Loop ofthe Left Ventricle andthe
ProximalAorta in the Conscious DogKerkhof, Peter L.; Li, John K.-J. 3636
Cardiac Parametric Variations in Post-Ischemic
MyocardiumLi, John K-J; Zhu, Ying; Khaw, Kenneth; Kedem,
Joseph 3639
A Kalman FilteringApproach to Estimation ofMaximum Ventricle Elastance
Borella, Benedetta; Lucchi, Elena; Nicosia,Salvatore; Valigi, Paolo 3642
Computing Work in the Ischemic Heart
Niederer, Steven A.; Buist, Martin L.; Pullan,Andrew J.; Smith, Nicolas P. 3646
Frequency-BasedAnalysis ofDiastolic Function:
Detrimental Phase-Shift ofthe Pressure-FlowRelation Characterizes the 'Delayed Relaxation'
Transmural Flow Pattern
Wu, Yue; Kovacs, Sandor J. 3650
Evaluation oflsovolumic Relaxation Phase in
the Process of Ventricular Remodeling FollowingMyocardial InfarctionKheradvar, Arash; Gorman, Robert C; Gorman,
III, Joseph H.; Zeeshan, Ahmad; Gharib, Morteza 3654
Session 10.2.2: Modeling and Imaging of
Ventricular Mechanics
Model Generation Interfacefor Simulation ofLeft Ventricular Motion
Amano, Akira; Kanda, Kenichi; Shibayama,
Tsukasa; Kamei, Yuu; Matsuda, Tetsuya
Intracardiac Echocardiographic Measurement of
Left Ventricular Volume
Ding, Chuxiong; Rao, Liyun; Nagueh, Sherif F.;
Khoury, Dirar S.
Regional Differences in Systolic Active Stress
Profiles in the Normal BeatingHeart. Assesment
Using an Ultrasound BasedMathematical Model
Mc Laughlin, Myles; Langeland, Stian; Streb,
Witold; Marciniak, Maciej; D'hooge, Jan;
Bijnens, Bart; Claus, Piet
Construction ofthe Global Lagrangian Strain
Field in the Myocardium Using DENSE MRIData
Saber, Nikoo R.; Wen, Han
3658
3662
3666
3670
xlvii
Evidence of Time-Varying MyocardialContribution by In Vivo Magnitude and Phase
Measurement in Mice
Wei, Chia-Ling; Valvano, Jonathan W.; Feldman,Marc D.; Kottam, Anil; Altaian, David;Raghavan, Karthik; Fernandez, Daniel J.; Reyes,Maricela; Escobedo, Daniel; Pearce, John A. 3674
Track 10.3: Valvular and Vascular
Mechanics and Blood Flow
Session 10.3.1: Vessel Wall Mechanics
Hemodynamic Simulation of Vascular Prosthesis
Altering Pulse Wave PropagationChung, Juhyun; Li, John K-J. 3678
One Important Area Gradient Force Has Been
Omitted in the Moens and Korteweg's EquationJan, Ming-Yie; Hsiu, Hsi; Bao, Jian-Guo; Lin
Wang, Yuh-Ying 3681
Measurement ofPulse Wave }relocity usingMagnetic Resonance ImagingGao, Gang; Mark, Patrick; Cockshott, Paul; Foster,John; Martin, Thomas; Blyth, Kevin;Steedman, Tracey; Elliott, Alex; Dargie, Henry;Groenning, Bjoern 3684
Noninvasive Ultrasonic Measurement ofArterial
Wall Motion in Mice
Hartley, Craig J.; Reddy, Anilkumar K.; Madala,Sridhar; Entman, Mark L.;Michael, Lloyd H.; Taffet, George E. 3688
i Two-Layer Model ofthe Static Behaviour ofBlood Vessel Walls
Payne, Stephen J. 3692
Blood Flow through Axially Symmetric Sections
ofCompliant Vesselsrnew Effective Closed
Models
Canic, Suncica; Tambaca, Josip; Mikelic, Andro;
Hartley, Craig; Mirkovic, Dragan;Chavez, Joy; Rosenstrauch, Doreen 3696
Optimal Lymphatic Vessel Structure
Venugopal, Arun M.; Stewart, Randolph H.;
Rajagopalan, Shruti; Laine, Glen A.; Quick,
Christopher M. 3700
Session 10.3.2: Peripheral Vascular Flow
Doppler Ultrasound Determination oftheDistribution ofHuman Cardiac Output: Effects
ofAge and Physical Stresses
Greene, E. R.; Roach, R. C. 3704
Variations ofthe Maximum Blood Flow Velocityin the Carotid, Brachial and FemoralArteries in
a Passive Postural Changes by a DopplerUltrasound Method
Azhim, Azran; Hirao, Yuji; Kinouchi, Yohsuke;Yamaguchi, Hisao; Yoshizaki, Kazuo 3708
Cardiac Output Monitoring in Intensive Care
Patients by Radial Artery Pressure
Waveform AnalysisMukkamala, Ramakrishna; Kuiper, Jacob; Ahmad,Salman; Lu, Zhenwei 3712
A Comprehensive Physiological Model ofCirculation Enables AutomaticPiloting ofHemodynamics in Patients with Acute Heart
Failure
Sugimachi, Masaru 3716
Effect of Cellular Elements on Pressure-Velocity
Relationship in Mice
Reddy, Anilkumar K; Taffet, George E.; Prcha],JosefF.; Michael, Lloyd H.;Entman, Mark L.; Hartley, Craig J. 3720
Methodfor the Measurement ofthe Sensitivity ofVascular Beds to Ischemia
Maltz, Jonathan S. 3723
Session 10.3.3: Valvular Mechanics
Mechanics ofthe Mitral Valve: In Vitro Studies
Jimenez Jorge, Ritchie Jenniffer, Zhaoming He,
Yoganathan Ajit P. 3727
Development ofMarkers of Valve StiffnessforPrediction ofHemodynamic Progression ofAortic Stenosis
VanAuker, Michael D.; Rhodes, Katherine; Singh,Alok.; Strom, Joel A. 3730
A Structural Constitutive Modelfor the Native
Pulmonary Valve
Sacks, Michael S.; Lam, Thanh V.; Mayer, Jr.,John E. 3734
Fibrotic vs. Myxomatous Remodeling ofMitralValves
Grande-Allen, K. Jane 3737
Skewness Angle ofInterfibrillar ProteoglycanIncreases with Applied Load on Chordae
Tendineae
Liao, Jun; Vesely, Ivan 3 741
Modelling Chorded Prosthetic Mitral ]ralves
using the Immersed Boundary Method
Watton, Paul N.; Luo, Xiao Yu; Singleton, Roger;Molloy, Paul; Bernacca, Gill M.; Wheatley, David
J. 3745
xlviii
Session 10.3.4: Cardiovascular SystemsParameter Estimation by Descent and GeneticAlgorithm Methods ofan In-Vitro StenosisBypass Model
Woo, Tony; Palafox, Gilbert; Diong, Bill; WickerRyan
'
3749
Endothelium-Independent Vasorelaxant Effect ofLidocaine in RatAortic RingsShan, Qi-Xian; Lin, Ding-Sheng; Jin, Hong-Feng;Gao, Qin; Lu, Yuan; Xia, Qiang 3753
The Endothelium-independent VasorelaxantEffect ofPuerarin on Rat ThoracicAortaDong, Kan; Tao, Qian-Min; Shan, Qi-Xian; Jin,Hong-Feng; Pan, Guo-Biao; Zhu, Jian-Hua;Chen, Jun-Zhu; Xia, Qiang 3757
Session 10.3.5: Cardiopulmonary AssistDevices
Hemodynamic andLeft VentricularPressure-Volume Responses to Counterpulsation in MockCirculation andAcute LargeAnimal ModelsKoenig, Steven G; Pantalos George M.; Litwak,Kenneth N.; Gillars, Kevin J.; Giridharan,Guruprasad A.; Maguire, Mark; Spence, Paul A.
Recent Progress ofMoving-Actuator TypeMechanical Circulator}' Support Systems:AnyHeart and T-PLS
Min, Byoung Goo
An ArchitectureforRapidPrototyping of Control
Schemesfor Artificial Ventricles
Ficola, Antonio; Pagnottelli, Stefano; Valigi,Paolo; Zoppitelli, Maurizio
In Vitro Evaluation ofControl Strategiesfor an
Artificial Vasculature Device
Glower, Jacob S.; Cheng, Rolando; Giridharan,Guruprasad A.; Gillars, Kevin J.; Pantalos, GeorgeM.;Litwak, Kenneth N.; Ewert, Dan L.; Koenig,Steven C.
Dynamic Response ofthe Pulmonary Circulation
in Continuous FlowArtificialHeart Systems
Olegario, Paul S.; Yoshizawa, Makoto; Tanaka,
Akira; Shiraishi, Yasuyuki; Ogawa, Daisuke;Hanaoka, Tetsubumi; Abe, Ken-ichi; Yambe,
Tomoyuki; Nitta, Shin-ichi
A Closed-Loop Model ofthe Ovine
Cardiovascular SystemHa, Roy; Qian, Junhui; Wang, Dongfang;Zwischenberger, Joseph B.;
Bidhani, Akhil; Clark, Jr., John W.
3761
3765
3769
3773
3777
3781
Energetics andHemodynamic Changes ofNormal and trartous Right Heart Bypass(Fontan) Circulations in Lambs under VaryingRespiration ParametersKetner, Mark E.; Lucas, Carol L ; Mill, MichaelR.; Sheridan, B.; Lucas, W, 3715
Session 10.3.6: Coronary Blood FlowDynamics
Flow Patterns and WallShear StressDistributions at Atherosclerotic-Prone Sites in aHuman Left Coronary Artery - An ExplorationUsing CombinedMethods ofCTandComputationalFluid DynamicsSuo, Jin; Yan, Yang; Oshinski, John;Tannenbaum, Allen; Gruden, James; Giddens, Don
3789
Devices to Improve CoronaryArtery BypassGrafting (CABG) SurgeryHoagland, Benjamin D.; Ryan, Thomas P.;Durrani, Amir K.; Burton, Lucas J.; Tumkur,Santosh K. 3792
A Systemfor On-Line Laser Doppler MonitoringofECG-TracedMyocardialPerfusionFors, Carina; Karlsson, Daniel M. G.; Ahn, Henrik
C; Wardell, K. 3796
BloodFlow in Stented Coronary Artery:Numerical FluidDynamics AnalysisBenard, Nicolas; Perrauit, Robert; Coisne,Damien 3800
Identification ofBrachialArtery Characteristic
Using a Cufffor Noninvasive Detection ofCoronary Artery Disease
Pouladian, Majid 3804
A ComputationalModel ofMicroctrcutatoryNetwork Structure and Transient
Coronary Microcirculation
Lee, Jack C. J.; Pullan, Andrew J.; Smith, Nicolas
p. 3808
Track 10.4: Respiratory Systems and
Sleep Apnea
Session 10.4.1: Swallowing and
Respiratory Systems Analysis
Analysis ofNormalSwallowing Sounds UsingNonlinear Dynamic Metric Tools
Aboofazeli, Mohammad; Moussavi, Zahra 3812
Automated Classification ofSwallowing and
Breath Sounds
Aboofazeli, Mohammad; Moussavi, Zahra 3816
xlix
Swallowing Sound Characteristics in HealthyandDysphagicIndividuals
Lazareck, Lisa J.; Moussavi, Zahra 3820
Adaptive Modeling ofSound Transmission in the
Respiratory SystemCiftci, Koray; Yeginer, Mete; Sen, Ipek; Cini,Ugur; Kahya, Yasemin P. 3824
A Comparison ofVarious Respiratory SystemModels Based on Parameter Estimates From
Impulse Oscillometry DataWoo, Tony; Diong, Bill; Mansfield, Lyndon;Goldman, Michael; Nava, Patricia; Nazeran,
Homayoun 3828
Session 10.4.2: Lung Sounds: Modeling,Classification and Analysis
On Applying Continuous Wavelet TransforminWheezeAnalysis
Taplidou, Styliani A.; Hadjileontiadis, Leontios J.;Kitsas, Ilias K.; Panoulas, Konstantinos I.;Penzel, Thomas; Gross, Volker; Panas, Stavros
M.
Analysis of Wheezes in Asthmatic Patients during
Spontaneous RespirationJane, Raimon; Cortes, Sandra; Fiz, Jose A.;Morera, Jose
Heart Sound Cancellation Based on Multiscale
Prodcut and Linear Prediction
Moussavi, Zahra; Flores, Daniel; Thomas, Gabriel
Classification ofLung Sounds during Bronchial
Provocation Using Waveform Fractal
Dimensions
Gnitecki, January E.; Moussavi, Zahra;
Pasterkamp, Hans
Classification ofPulmonary Diseases Based on
Impulse Oscillometric Measurements ofLungFunction Using Neural Networks
Barua, Miroslava; Nazeran, Homayoun; Nava,
Patricia; Granda, Virginia; Diong, Bill
Finding the Lung Sound-Flow Relationship in
Normal andAsthmatic SubjectsHossain, Irina; Moussavi, Zahra
3832
3836
3840
3844
3848
3852
Session 10.4.3: Sleep Apnea I: Diagnosticand Therapeutic Modalities
Ambulatory Recording ofSleep Apnea Using
Peripheral Arterial TonometryPenzel, Thomas; Kesper, Karl; Ploch, Thomas;
Becker, Heinrich F,; Vogelmeier, Claus 3856
The Use ofEsophageal Manometry in the
Diagnosis ofSleep-Related Breathing Disorders
Kushida, Clete A. 3860
Central Aortic Pressure Wave Changes with
SleepStage andDisordered Breathing in
Children Estimated by Application ofan Arterial
Transfer Function to PeripheralBloodPressure
McConnell, Keith B.; Wagner, M.; Urbina, E.;
Daniels, S.; Helmicki, A.; Hunt V.; Amin, R. S. 3864
Non-invasive Estimation ofEsophageal Pressure
Based on Intercostal EMG MonitoringStoohs, Riccardo A.; Blum, Hans-Christian;
Knaack, Lennart; Guilleminault, Christian 3867
NoninvasiveAssessment ofCardiovascular
Autonomic Control in Congenital Central
Hypoventilation SyndromeLin, Zheng; Chen, M. L.; Keens, T. G.; Ward, S.
L. D.; Khoo, M. C. K. 3870
Long-Term Monitoring ofSleep Apnea at Home
in Heart Failure Patients: Preliminary Results
from the HHHStudyPinna, Gian Domenico 3874
Women Have a Greater Ventilatory Responses to
Upper Airway Obstruction in Than Men
Pichard, Luis E.; Patil, Susheel P.; Gladmon,
Elisabeth; Smith, Philip L.;Schwartz, Alan R; Schneider, Hartmut 3878
Session 10.4.4: Sleep Apnea II: Analysisof Cardiorespiratory Variability
The Use ofR-Wave Morphology in the Detection
ofSleep-Disordered Breathing Using the
Electrocardiogram- a Comparison Between
Leads
Vijendra, S.; Behbehani, Khosrow; Lucas, E. A.;
Burk, J. R.; Burli, D. N; Dao, D. H. 3881
Time Domain Analysis ofR-Wave Attenuation
Envelopefor Sleep Apnea Detection
Suhas, SanjeeR.; Behbehani, Khosrow; Vijendra,Sridhar; Burk, John R.; Lucas, Edgar A. 3885
Heart Rate Chaos in Obstructive Sleep Apnea In
Children
Zapanta, Laurence F.; Poon, C.-S.; White, D. P.;Marcus, C. L.; Katz, E. S. 3889
Closed-Loop Minimal Model Analysis oftheCardiovascular Response to Transient Arousal
from Sleep in Healthy Humans
Blasi, Anna; Khoo, Michael C. K.; Jo, Javier;Valladares, Edwin; Juarez, Ricardo; Baydur,Ahmet N. 3893
The Effects ofRepetitive Arousalfrom Sleep on
CardiovascularAutonomic Control
Chaicharn, J.; Carrington, M.; Trinder, J.; Khoo,M. C.K. 3897
Simulation ofSpontaneous Cardiovascular
Variability Using PNEUMA
Ivanova, Olga V.; Khoo, Michael C. K. 3901
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