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From DATRI’s Desk

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We as sensitive human beings always want to see everybody happy, healthy and at peace. While many are contended and leading a healthy life, a large section of the society is deprived of it. ‘Being healthy’ is just a distant dream for them. Patients with deadly blood disorders are one among them, who are battling against various life threatening diseases every day. They and their family can be relieved of their sufferings by our simple act of kindness.

According to the ICMR, in India in 2010 around 1,04,239 blood and lymphatic malignancies were diagnosed and the number is expected to increase to 1,32,574 cases per year by 2020. For many patients Blood Stem Cell transplant is the only hope of cure for these fatal disorders and finding an HLA matched donor is an essential initial step to find this permanent cure.

DATRI currently has searches for over 2000+ patients and many more patients in India are waiting for a match. While they wait for their life saving match, they undergo chemotherapy. So, in many of the cases, by the time the elusive match is found, either the chemotherapy takes the patient or the cancer does. The best case situation is one where, when a patient comes to us looking for a match, we are able to find him/her a match immediately from the already registered donors and can facilitate the donation immediately, thereby significantly increasing the patient’s chances of survival and reducing the subsequent cost of treatment. But in order to do so, keeping in mind the very low odds of finding a match, there is a need for a much larger registry. At DATRI our dream is to make the society free from fatal blood disorders, which is only possible by contributions from generous socially sensitive folks.

Our registry currently has about 3, 80,000 registered donors. We have facilitated 442 blood stem cell donations till date. However, the odds of finding a match is 1:10,000 to 1:10,00,000.

We are committed to expanding the nationwide registry across all parts of India. However, each registration costs DATRI Rs.1800 towards HLA typing cost. On receiving funding support from generous people in the society, DATRI can multiply its efforts and together we can strive to save more lives.

When you donate money to DATRI you are saving lives. Blood cancer is on the rise and there are several families which need financial support for testing their friends and family members in order to find that elusive match to save their loved one's life. They rely on the act of kindness by a stranger who will help cover this cost. And this act of kindness does not go in vain. It carries forward as ripples - because the friends and family members whose lab costs have been paid for will get added to the DATRI database and they in turn agree to donate their stem cells for a patient in the future, if they are ever a match. Thus not only do you help families which are down on their luck, you also help create the ripples that spread and help grow the registry that will continue to save many more lives.

There are many ways for you to help people receive the life-saving transplant they need. Give a onetime gift; Give a monthly gift, Donate in honour of someone etc. Every INR 1800/- raised adds a potential Blood Stem Cell donor to DATRI.

To save the life of the patient of blood cancer is in the hands of ordinary people like you. Help save a life.

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Sonali A. BhandarkarManager, CSR Initiatives

At DATRI our dream is to make the society free from fatal blood disorders, which is only possible by

contributions from generous socially sensitive folks.

‘No one has ever become poor by giving’ - Anne Frank

Each of them is battling against time. You can be the champion of these young lives. Be a blood stem cell donor and save childhood.

#HelpAlesha find a HLA matched Donor.Mehreen Kajani, Mother of Alesha Kajani*

DATRI’s Corner

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In anticipation of a lifesaver.

Muhammed Asnan,

4 years olddiagnosed with

Leukemia

#HelpAsnanNiya Fathima,

6 year old, diagnosed

with Thalassemia

#SaveNiya

#SaveRohit

Navika Bansal, 2 year old,diagnosed

with Thalassemia

#GiftALifeToNavika

Hi everybody, I am the mother of a 17-month-old baby girl, her name is Alesha . Alesha has been diagnosed with a bone marrow failure and with her condition right now she is going for transfusions twice a week for platelets and sometimes for red blood cell counts as well. Her veins are very small so she needs a VAT (Vascular Access) Team, who can come in and look for her veins. It’s extremely painful for her to go through twice a week. Her condition right now is deteriorating. She is having a lot of adverse reaction with platelets. Her organs are beginning to fail. The major problem we see is she is unable to gain any weight at all; it has been over a year and she has plateaued. So it’s a humble request to everybody out there, I don’t care what race, what creed, what ethnicity you are. Please go ahead and sign up, donate. You never know whose life you are going to save and the prayers and thanks you are going to receive. Thank you for patiently listening to my plea.

Alesha Kajani, 14 months,

diagnosed with Bone Marrow Failure

Rohit, 5 year,

diagnosed with Thalassemia

*(Transcribed from the audio appeal from Ms. Mehreen)

DATRI in News

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Pathrika, Sagar on 10/09/2018

Deccan Chronicle, Chennai on 03/09/2018

Andhrajyothi, Vijayawada on 25/07/2018

Sakshi, Kadappa on 01/08/2018

Andhrapraba, Vijayawada on 31/07/2018

Prajasakti, Vijayawada on 20/07/2018

Aluva on 23/07/2018

Aluva on 23/07/2018

Ei Samay, Kolkata on 25/07/2018

Gift a life and take a healthier lifestyle as a return gift.

DocTalk

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Dr. Jose M EasowConsultant in Medical Oncology & Hematology,

Apollo Cancer Speciality Hospital, Chennai.

Upkeep of good health is essential especially for a donor of Blood Stem Cells, since micronutrients such as vitamins, dietary minerals, essential fatty acids, and essential amino acids, play a

vital role in efficient yield of the Blood Stem Cells.

The gift of life is the most treasured gift one could ever give. The modern medicine has done a miracle in finding a permanent cure for patients with several acquired and inherited malignant and non-malignant disorders, in the form of Hematopoietic Stem Cell Transplantation (HSCT). Registries such as DATRI are rendering an impressive service by recruiting blood stem cell donors and connecting them with the patients in need. The interesting aspect of being a donor of blood stem cells is not just one can be a savior for someone by gifting a life but also can adopt several corrective measures to improve one’s own lifestyle, which will yield long-term benefits on their holistic health.

Having associated with DATRI as a Medical Director, I asses the health condition of the donors based on their health check-up reports. The examination of the medical reports of a sample group of donors has revealed that around 68% have Vitamin D deficiency, 51% are deficient in vitamin B12, almost 9% have iron deficiency and 8% suffer from fatty liver. This clearly shows the impact of their lifestyle on their health. Less exposure to sunlight, intake of food which is deficient in essential nutrients, lack of leisure and lack of work-life balance are some of the causes. Bringing a few positive changes in terms of taking a balanced diet, turning away from a closed-door culture and connecting with nature, a regular exercise regime can result in remarkable improvements.

Upkeep of good health is essential especially for a donor of Blood Stem Cells, since micronutrients such as vitamins, dietary minerals, essential fatty acids, and essential amino acids, play a vital role in efficient yield of the Blood Stem Cells. Therefore, the donors are also prescribed and provided with nutrition supplement medication, which will benefit both the donors and the process of donation. Therefore by being a donor and gifting a life, one is receiving a return gift of an opportunity to know one’s own status of health and improve the same.

68%8%

9%

58%

Statistics on nutritional deficiency among registered donors at DATRI*

Vitamin D deficiency

Vitamin B12 Deficiency

Iron Deficiency

Fatty Liver

* Among a chosen sample size

It happened @ DATRI

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Taking cheek swab of Anwar Sadath - MLA, Aluva (Cochin)

Drawing competition among studentson account of WMDD*, Surat

‘Cycle to Gift a Life’ 2018, Chennai

Radio show with RJ Kshitij on WMDD, Vadodara

Donor Recruitment Drive at AG & SGS College, Vijayawada

‘Run to Save a Life’on account of WMDD, Kolkatta

Donor Recruitment Drive with Fire & Rescue Services team on account of WMDD, Trichy

‘Walk to save a life’ conducted,Vizag on account of WMDD

Bib Collection before the event,‘Cycle to Gift a Life’ 2018, Chennai

Donor Recruitment Drive at Presidency College during the observation of Kargil Day

Poster Campaign,Genpact, DLF Ph-5, Gurgaon

Donor Recruitment Drive, Genpact Kolkata

Honouring the donor at‘Terry Fox Run’, Chennai

Donor Recruitment Drive, ‘Terry Fox Run’, Chennai

*World Marrow Donor Day

Registration Process

Donation ProcessIf an individual is found to be a match, there are two ways of donating blood stem cells i.e. Peripheral Blood Stem Cell (PBSC) donation and Bone Marrow Harvest. For a PBSC donation, once the donor completes the master health check-up, he/she will be given an injection called Granulocyte-Colony Stimulating Factor(GCSF) for 5 days to stimulate the blood stem cells production and bring them from the marrow to the blood stream. Blood Stem Cells will be collected in a 4-5 hours of out-patient procedure called Apheresis. For a Bone Marrow Harvest, the marrow will be collected from the hip bone of the donor under general Anesthesia. Here is a visual representation of the procedure.

When an individual comes forward to register as a blood stem cell donor, he/she becomes a potential life-saver. Anyone between the age of 18-50 years can register as a blood stem cell donor. Registration is simple - the registration process is represented below:

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Registration Process

FILL THE APPLICATION FORM

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SIGN THE CONSENT FORM

5

GIVE A CHEEK SWAB

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DONATE INR 1800 FOR YOUR HLA TYPING

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www.datri.org

www.datri.org

HLA TYPING

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PERIPHERAL BLOOD STEM CELL DONATION

(PBSC)

BONE MARROWDONATION

VERIFICATION OF MATCH

1

MASTER HEALTH CHECK UP

2

3 TRANSPORTATION

(OR)

4

5

TRANSPLANTATION

DONATION(TWO WAYS)

1

ATTEND AN AWARENESS

SESSION ELIGIBILITY

18 - 50 YEARS

2

INDIA

Delhi

Gujarat

Maharashtra

Andhra Pradesh

640

4,882

234

2,406

19Telangana

950

4,360

125

DATRI Dashboard

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(July - September 2018)

Statewise number of donors registered

Donations

July - 12 September - 13August - 15

JAN

- M

AR

APR - JUN JUL AUG SEP OCT - D

EC

0 1,80,000

35

,365

2

0,247 15,455 711 1,348

Life Savers Added & Lives Gifted

Goals 2018

1,938Tamil Nadu

Kerala

Karnataka

Andhra Pradesh

West Bengal

Maharashtra

Gujarat

Delhi

TamilNadu

Kerala

Karnataka

WestBengal

Haryana 1,051

Uttar Pradesh

Rajasthan 155

Madhya Pradesh 170

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This year DATRI intends to recruit 1,00,000 donors. The cost of HLA typing for all the donors will amount to INR 18 crores.

Let’s make this possible! Register as Blood Stem Cell donors and donate money to support DATRI’s life saving mission.

www.datri.org

www.datri.org

Registrations

This includes both Collection and Transplant Centers that DATRI has worked with until now.

Talk to us

Do get in touch with us with your comments, feedback and suggestions on this edition as well as on topics / information that you would like to read about in future editions. Write to us at marcom@datri.org. We are looking forward to your inputs.

1207 -1208, 12th floor, Ticel Bio Park Phase 2, CSIR Road, Taramani, Chennai - 600113, India. Phone : +91 44 2254 1283, +91 44 4079 5300 Toll-Free Number: 1-800-300-32874

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www.facebook.com/datriworld www.twitter.com/datriworld https://www.instagram.com/datriworld

www.datri.org/join https://in.linkedin.com/company/datri-blood-stem-cell-donors-registry

Donations to DATRI are exempt from taxunder section 80G of the Income Tax Act.

Account Name : DATRI Blood Stem Cell Donors RegistryAccount No : 000584000001189 Bank Name : Yes Bank LtdBranch Name : Uthamar Gandhi Salai, Nungambakkam, ChennaiIFSC Code : YESB0000005 Swift Code : YESBINBBXXX

It costs DATRI Rs. 1800/- to add a donor to the registry. DATRI is targeting to recruit 1,00,000 donors this year, to save more lives. We are in urgent need of funds and your monetary support will help our cause.

Paytm

Scan to Donate Money

Online payment

http://datri.org/donate-now/Number+91 9042018667

Our Hospital Partners* AIMS, Kochi* Apollo Hospitals, Ahmedabad, Chennai, Delhi, Kolkata, Hyderabad * ACIBADEM University Hospital, Istanbul* ARTEMIS Hospital, Gurgaon* Adana Acibadem Hospital, Turkey* AOUI Verona, Italy* AMRI Hospital, KI* Ampang Hospital, Singapore* Asiri Central Hospital, Srilanka* Baylor University Medical Center, USA* Barnes Jewish Hospital* BGS Global, Bangalore* Birmingham Children's Hospital, Birmingham, UK* BL Kapoor Hospital, Delhi* CMC Vellore, Ludhiana* City of Hope, Los Angeles, USA* Cancer Institute, Adyar* Deenanath Mangeshkar Hospital, Pune* Dr.L.H Hiranandani Hospital, Mumbai* Direttore U.O.C. Onco-ematologia Pediatrica,Verona, Italy* Duke Medical Centre, NC, USA* Fortis Memorial Research Institute, Gurgaon* GCRI, Ahmedabad

* Hospital St Louis* Hammersmith Hospital, London* HCG, Bangalore* Hiranandani Hospital, Mumbai* Hematology Oncology & SCT and Research Center, Iran* Jaypee Hospital, Noida* Kings Hospital, London* Medanta-The Medicity, Gurgaon* Meenakshi Mission Hospital & Research Centre, Madurai* Manipal Hospital, Bangalore* Medical Park Bahcaelievler Hospital, Istanbul* M D Anderson Cancer Center, USA* MIOT Hospital, Chennai* Mayo Clinic Rochester, NY, USA* Medipol University, Turkey* Medical City Dallas Hospital, Dallas, USA* Narayana Health, Bangalore* Indo American, Hyderabad* KIMS Hospital, Hyderabad* Kovai medical Center and Hospital, Coimbatore* Nanavati Speciality Hospital, Mumbai* Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute, Mumbai* Malabar Cancer Centre, Kerala

* Nawaloka Hospital, Srilanka* University Hospital of Cleveland, OHIO, USA* University College Hospital, London* Sir Ganga Ram Hospital, Delhi* Sisli Kolan International Hospital, Turkey* PD Hinduja Hospital, Mumbai* PGIMER, Chandigarh* Queen Elizabeth Hospital, Birmingham, UK* Rajiv Gandhi Cancer Institute, Delhi* Rosewell Park Cancer Institute, NY, USA* Royal Manchester Children’s Hospital, UK* Royal Melbourn Hospital, Australia* Royal Brisbane and Women’s Hospital, Australia* Sahyadri Superspeciality Hospital, Pune* Sterling Hospital, Ahmedabad* SRMC, Chennai* Southampton, Hampshire, UK* TMC Hospital, Kolkata* TMC Hospital, Mumbai* TCH The Children's Hospital, Boston, USA* UCSF, San Fransisco, USA* Vienna University Hospital, Austria* North Side Hospital, USA* Prince margaret Hospital, Canada* Raffles Hospital, Singapore* St. Vincent Hospital, Sydney* University Hospital of Wales, Cardiff, UK* Yashoda Hospital, Hyderabad

www.datri.org

www.datri.org

Across:3. A blood disorder that fails to make enough Hemoglobin is called_____.5. A donor who has this breathing problem-______ are completely from donating. 7. Blood Stem Cell Collection which happens in an outpatient called___________ 10. ________ typing is required for finding a donor match. 11. Bone Marrow is harvested from the hipbone otherwise known as__________ of the donor’s body .13. A patient has to undergo______________ before the donor’s stem cells 14. ________ is celebrated every third Saturday of September16. A person who transports blood stem cells for transplant__________

Down:1. The first step to save a life- ___________ 2. Blood Stem Cells should not be exposed to ___________ 4. Blood cancer that affects the white blood cells (WBC) is process is called_____________ 6. Blood Cancer that affects the lymphatic system is called____ 8. Patients and donors compatibility is determined by_______ 9. ___________-CSF is given to a donor for blood stem cellmobilization.12. A therapy to destroy cancer cells______________15. A registered donor has to be between the age of eighteen to ____________

Answers 1) Registration 2) X-RAY 3) Thalassemia 4) ) Leukemia 5) Asthma 6) Lymphoma 7) Apheresis 8) Match-rank 9) Granulocyte 10) HLA 11) Iliac Crest 12) Chemotherapy 13) Conditioning 14) WMDD 15) Fifty 16) Courier

Cross Word

DATRI Knowledge Crossword