Aleksandr Noy Physical and Life Sciences Directorate Lawrence Livermore National Laboratory L-179, 7000 East Ave. Livermore, CA 94070, USA E-mail: [email protected]; [email protected]Education Harvard University, Cambridge, Massachusetts, USA Ph.D., Chemistry, December 1997 • Dissertation Topic: “Chemical Force Microscopy” • Advisor: Charles M. Lieber Harvard University, Cambridge, Massachusetts USA M.A., Chemistry, May 1995 Moscow State University, Moscow, Russia B.A., Chemistry/Physics, cum-laude (“диплом с отличием”), May 1992 Present Position 02/12-pres. Senior Research Scientist Physical and Life Sciences Directorate, LLNL 07/04-pres. Adjunct Professor (current rank: Full Professor Step II) School of Natural Sciences, University of California, Merced Previous Positions 03/10-02/12 Researcher (Step VII) School of Natural Sciences, University of California, Merced 02/10-02/12 Chief Science Officer (on an Entrepreneurial leave from LLNL) Porifera, Inc., Hayward, CA 03/06-01/10 Team Leader Molecular Biophysics and Functional Nanostructures Group, LLNL 07/05-03/06 Deputy Scientific Capability Leader Molecular Biophysics and Functional Nanostructures Group, LLNL 07/01-06/05 Staff Scientist Materials Science and Technology Division, LLNL 07/98-07/01 E.O. Lawrence Postdoctoral Fellow, LLNL (Fellowship mentor: Dr. James J. De Yoreo)
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Aleksandr Noy Physical and Life Sciences Directorate Lawrence Livermore National Laboratory L-179, 7000 East Ave. Livermore, CA 94070, USA E-mail: [email protected]; [email protected]
Education Harvard University, Cambridge, Massachusetts, USA Ph.D., Chemistry, December 1997
• Dissertation Topic: “Chemical Force Microscopy” • Advisor: Charles M. Lieber
Harvard University, Cambridge, Massachusetts USA M.A., Chemistry, May 1995
Moscow State University, Moscow, Russia B.A., Chemistry/Physics, cum-laude (“диплом с отличием”), May 1992
Present Position 02/12-pres. Senior Research Scientist
Physical and Life Sciences Directorate, LLNL
07/04-pres. Adjunct Professor (current rank: Full Professor Step II) School of Natural Sciences, University of California, Merced
Previous Positions 03/10-02/12 Researcher (Step VII) School of Natural Sciences, University of California, Merced
02/10-02/12 Chief Science Officer (on an Entrepreneurial leave from LLNL) Porifera, Inc., Hayward, CA
03/06-01/10 Team Leader Molecular Biophysics and Functional Nanostructures Group, LLNL
Published/In press/Accepted 102. Z. Hemmatian, R.H. Tunuguntla, A. Noy, M. Rolandi Electronic control of H+ current
in a bioprotonic device with carbon nanotube porins, PLOS One, v. 14(2): e0212197 (2019).
101. X. Chen. H. Zhang, R.H. Tunuguntla, A. Noy Silicon nanoribbon pH sensors protected by a barrier membrane with carbon nanotube porins, Nano Lett., 19, 629−634 (2019), Front Cover.
100. J.R. Sanborn, X. Chen, Y.-C. Yao, J. A. Hammons, R.H. Tunuguntla, Y. Zhang, C. Newcomb, J. Soltis, J.J. De Yoreo, A. Van Buuren, A.N. Parikh, A. Noy Carbon
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Nanotube Porins in Amphiphilic Block-Copolymers as Fully-Synthetic Mimics of Biological Membranes Adv. Mater., v.30(51) p.1803355 (2018) Frontispiece Cover.
99. J.B. In, K.R. Cho, T.X. Tran, S-M. Kim, Y. Wang, C.P. Grigoropoulos, A. Noy, F. Fornasiero Effect of Enhanced Thermal Stability of Alumina Support Layer on Growth of Vertically Aligned Single-Walled Carbon Nanotubes and their Application in Nanofiltration Membranes, Nanoscale Res. Lett., v.13, p.173 (2018).
98. R.H. Tunuguntla, A.Y. Hu, Y. Zhang, A. Noy Impact of PEG additives and pore rim functionalization on water transport through sub-1-nm carbon nanotube porins, Faraday Disc., v. 209, 359 – 369 (2018).
97. R. H. Tunuguntla, Y. Zhang, R. Y. Henley, Y-C. Yao, T. A. Pham, M. Wanunu, A. Noy Response to Comment on “Enhanced water permeability and tunable ion selectivity in sub-nanometer carbon nanotube porins” Science v. 359, eaaq1241 (2018).
96. W. He, M. Felderman, A.C. Evans, J. Geng, D. Homan, F. Bourquet, N.O. Fischer, K.S. Lam, A. Noy, H. Cheng, A. Rasley, C. Blanchette, K. Kamrud, N. Wang, H. Gouvis, B. Hubby, M.A. Coleman Cell-free Production of a Functional Oligomeric Form of a Chlamydia Major Outer Membrane Protein (MOMP) for Vaccine Development, J. Biol. Chem., jbc.M117.784561 (2017).
95. R. Tunuguntla, R. Henley, Y.-C. Yao, T.A. Pham, M. Wanunu, A. Noy Enhanced water permeability and tunable ion selectivity in sub-1-nm carbon nanotube porins, Science, v. 357, p. 792–796 (2017).
• Highlights in C&E News, Chemistry World, The Verge. • Our desalination research was covered in a news feature produced and
published by Google, with a direct link from google.com homepage on 11/3/17: § https://www.google.com/intl/en/about/stories/scientists-could-make-oceans-drinkable/
§ Cover story in Sacramento News & Entertainment Review, January 18, 2018 94. X. Ma, S Zhang, F. Jiao, C. Newcomb, Y. Zhang, A. Prakash, Z. Liao, M. Baer, C.
Mundy, J. Pfaendter, A. Noy, C.-L. Chen, J. De Yoreo Tuning crystallization pathways through sequence-engineering of biomimetic polymers, Nature Materials, v. 16, p. 767–774 (2017).
• Front Cover, July 2017 issue. 93. R.H. Tunuguntla, A. Belliveau, X. Chen, A. Noy High-Yield Synthesis and Optical
Characterization of Carbon Nanotube Porins, J. Phys. Chem. C, v. 121 (5), p. 3117–3125 (2017)
92. Y. Zhang, R.H. Tunuguntla, P-O. Choi, A. Noy Real-time dynamics of carbon nanotube porins in supported lipid membranes visualized by high-speed AFM, Phil. Trans. Roy. Soc. B., v. 372, p. 20160226 (2017).
• Front Cover, June 19, 2017 issue. 91. R. H. Tunuguntla, A. Escalada, V. Frolov, A. Noy Synthesis, lipid membrane
incorporation, and ion permeability testing of carbon nanotube porins, Nature Protocols, v.11 (10), p. 2029–2047 (2016)
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90. I.C. Tran, R. H. Tunuguntla, K. Kim, T. Willey, J.R.I. Lee, T. Weiss, A. Noy, T. van Buuren Structure of Carbon Nanotube Porins in Lipid Bilayers: an In-Situ Small-Angle X-ray Scattering (SAXS) Study, Nano Letters, v.16 (7), p. 4019–4024 (2016)
89. R. H. Tunuguntla, F. I. Allen, K. Kim, A. Belliveau, A. Noy Ultra-Fast Proton Transport in Sub-1-nm Diameter Carbon Nanotube Porins, Nature Nanotechnology, v.11 (7), p. 639-644 (2016).
• Article graphics featured on the TOC page of the issue 88. C. M. Ajo-Franklin, A. Noy Crossing Over: Nanostructures that Move Electrons and
Ions Across Cellular Membranes Advanced Materials, v. 27 (38), p. 5797-5804 (2015)
• Front Cover, Oct 2015 issue. 87. J. R. I. Lee, M. Bagge-Hansen, R. Tunuguntla, K. Kim, M. Bangar, T. M. Willey, I.C.
Tran, D. Kilcoyne, A. Noy, T. van Buuren, Ordering in Bio-inorganic Hybrid Nanomaterials Probed by In Situ Scanning Transmission X-ray Microscopy Nanoscale, v. 7, p. 9477-9486 (2015), Front Cover.
86. R. Wyss, J.E. Klare, H.-G. Park, A. Noy, O. Bakajin, V. Lulevich Water-assisted growth of uniform 100 mm diameter SWCNT arrays, ACS Appl. Mater. Interfaces, v.6 (23), p. 21019–21025 (2014).
85. R. Tunuguntla, M. Bangar, K. Kim, P. Stroeve, C. P. Grigoropoulos, C.M. Ajo-Franklin, A. Noy Light-powered bioelectronic devices with biologically-tunable performance, Advanced Materials, v. 27, p. 831-836 (2015).
• Front Cover, Feb 2015 issue. 84. K. Kim, J. Geng, R. Tunuguntla, C. P. Grigoropoulos, C. M. Ajo-Franklin, A. Noy
Osmotically-Driven Transport In Carbon Nanotube Porins, Nano Letters, v. 14, p. 7051–7056, DOI: 10.1021/nl5034446 (2014).
83. J. Geng, K. Kim, J. Zhang, R. Tunuguntla, L. R. Comolli, F. I. Allen, K. R. Cho, D. Munoz, Y. M. Wang, C. P. Grigoropoulos, C. M. Ajo-Franklin, A. Noy Stochastic Transport and Gating in Carbon Nanotube Porins in Lipid Membranes, Nature, v.514, p. 612-615 (2014).
• Research Highlight by Nature Methods, 11, 1194 (2014) • Editor’s Choice Highlight by Science Translational Medicine, 6, 264ec203 (2014)
82. R. Tunuguntla, M. Bangar, K. Kim, P. Stroeve, C.M. Ajo-Franklin, A. Noy, Lipid Bilayer Composition Can Influence the Orientation of Proteorhodopsin in Artificial Membranes, Biophys. J., v. 105, p. 1388 (2013).
81. A. Noy, In session: What makes an ideal conference (comment article), Materials Today, v.16, p. 48-49 (2013).
80. A. Noy, Kinetic Model of Gas Transport in Carbon Nanotube Channels, J. Phys. Chem. C., v. 117(15), p. 7656–7660 (2013).
79. A. Noy, R.W. Friddle Practical Single Molecule Force Spectroscopy: How to determine fundamental thermodynamic parameters of intermolecular bonds with an atomic force microscope, Methods, v.60, p.142–150 (2013).
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78. J-B. In, D. Lee, F. Fornasiero, A. Noy, C.P. Grigoropoulos Laser-assisted Simultaneous Transfer and Patterning of Vertically Aligned Carbon Nanotube Arrays on Polymer Substrates for Flexible Devices, ACS Nano, v.6 (9), p. 7858–7866 (2012).
77. R.W. Friddle, A. Noy, J.J. DeYoreo Interpreting the widespread non-linear force spectra of intermolecular bonds, Proc. Natl. Acad. Sci. USA doi:10.1073/pnas.1202946109 (2012).
76. J-B.In, C.P. Grigoropoulos, A. Chernov, A. Noy Growth Kinetics of Vertically Aligned CNT Arrays in Clean Oxygen-Free Conditions, ACS Nano v.5, p.9602-9610 (2011).
75. A. Noy Force Spectroscopy 101: How to design, perform, and analyze an AFM-based single molecule force spectroscopy experiment, Current Opinion in Chemical Biology (invited), v.15 (5), p. 710-718 (2011).
74. J-B. In, C.P. Grigoropoulos, A. Chernov, A. Noy Hidden role of trace gas impurities in chemical vapor deposition growth of vertically-aligned carbon nanotube arrays, Appl. Phys. Lett., v. 98, p.153102-153104 (2011).
73. V. Lulevich, S. Kim, C.P. Grigoropoulos, A. Noy Frictionless sliding of ssDNA in a carbon nanotube pore observed by single molecule force spectroscopy, Nano Letters, v.11, p. 1171–1176 (2011).
72. A. Noy, Bionanoelectronics, Advanced Materials v. 23, p. 807–820, invited review (2011)
• Front Cover 71. X. Wang, Y. Wang, D. Aberg, P. Erhart, N. Misra, A. Noy, A.V. Hamza, J. Yang,
Batteryless chemical detection with semiconducting nanowires Advanced Materials v.23, p. 117–121 DOI: 10.1002/adma.201003221 (2011).
• Inside Front Cover. 70. X.Y. Wang, K. Kim, Y.M. Wang, M. Stadermann, A. Noy, A.V. Hamza, J.H. Yang, D.J.
Sirbuly Matrix-assisted energy conversion in nanostructured piezoelectric arrays, Nano Letters v.10 (12), p. 4901–4907 (2010)
69. F. Fornasiero, J. In, S. Kim, H.G. Park, Y. Wang, C.P.. Grigoropoulos, A. Noy, O. Bakajin pH-Tunable Ion Selectivity in Carbon Nanotube Pores, Langmuir v.26 (18), p. 14848–14853 (2010)
68. S.-C. J. Huang, A.B. Artyukhin, N. Misra, J.A. Martinez, P.A. Stroeve, C.P. Grigoropoulos, J.-W.W. Ju, A. Noy Carbon nanotube devices controlled by an ion pump gate, Nano Letters v. 10 (5), p. 1812–1816 (2010)
• Research Highlight in Nature, 465, 139 (2010) • Highlighted by New Scientist (US), Chemistry World (UK), Discovery News (US),
Discover Magazine (US), Popular Science (US)
67. V.N. Shlyaptsev, J.J. Rocca, M. Grisham, G. Avaria, F. Tomasel, Noy, A. Prospective schemes for next generation x-ray lasers, Proc. SPIE, v. 7451, p 745103 (2009).
66. A. Noy, N. Misra, J. Martinez, Lipid-coated nanowires enable small-scale bioelectronics, SPIE Newsroom, DOI: 10.1117/2.1200911.1841 (2009)
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65. A. Noy, A. Artyukhin, N. Misra NanoBioElectronics with 1D Materials, Materials Today, v. 12 (9), p. 22-31, invited review (2009)
64. N. Misra, J.A. Martinez, S.-C. J. Huang, Y. Wang, P. Stroeve, C.P. Grigoropoulos, A. Noy Bioelectronic Silicon Nanowire Devices Utilizing Functional Membrane Proteins, Proc. Natl. Acad. Sci. USA, v. 106 (33), p. 13780–13784 (2009)
• Research Highlight in Nature, 460,934 (2009) • News and Views, Nature Physics, 5, 783 (2009) • Highlighted in MIT Technology Review (US), Computerworld (US), Popular
Mechanics (Russia) 63. O. Bakajin, A. Noy Separation Materials: Proteins make for finer filters, (News and
Views Feature) Nature Nanotechnology, v. 4, p. 345 – 346 (2009) 62. J.A. Martinez, N. Misra, Y. Wang, P. Stroeve, C.P. Grigoropoulos, A. Noy Highly-
efficient biocompatible single silicon nanowire electrodes with functional biological pore channels Nano Letters, v. 9 (3), p. 1121–1126 (2009)
61. M. Stadermann, S. P. Sherlock, J.-B. In, F. Fornasiero, H. G. Park, A. B. Artyukhin, Y. Wang, J. J. De Yoreo, C. P. Grigoropoulos, O. Bakajin, A. A. Chernov, A. Noy Mechanism and Kinetics of Growth Termination in Controlled Chemical Vapor Deposition Growth of Multiwall Carbon Nanotube Arrays, Nano Letters, v. 9 (2), p. 738–744 (2009)
60. T. Sulchek, R. Friddle, T. Ratto, H. Albrecht, S. De Nardo, A. Noy Single-Molecule Approach to Understanding Multivalent Binding Kinetics Ann. NY Acad. Sci. v. 1161, p. 74-82 (2009)
59. A. Barty, S. Marchesini, H. N. Chapman, C. Cui, M. R. Howells, D.A. Shapiro, A. M. Minor, J. C. H. Spence, U. Weierstall, J. Ilavsky, A. Noy, S. P. Hau-Riege, A.B. Artyukhin, T. Baumann, T. Willey, J. Stolken, T. van Buuren, J. H. Kinney Three-dimensional coherent X-ray diffraction imaging of a ceramic nanofoam: determination of structural deformation mechanisms Phys. Rev. Lett., v. 101, p. 55501 (2008)
58. F. Fornasiero, H-G. Park, J. K Holt, M. Stadermann, C. P. Grigoropoulos, A. Noy, O. Bakajin, Ion Exclusion by sub 2-nm Carbon Nanotube Pores Proc. Natl. Acad. Sci. USA, v. 105, p.17217-17221, invited contribution, Cover Article (2008).
57. D. J. Sirbuly, N. O. Fisher, S-C. J. Huang, A. Artyukhin, J. B.-H. Tok, O. Bakajin, A. Noy Biofunctional Subwavelength Optical Waveguides for Biodetection, ACS Nano, v.2 (2), p. 255–262 (2008)
56. R. W. Friddle, P. Podsiadlo, A. B. Artyukhin, A. Noy Near-Equilibrium Chemical Force Microscopy, J. Phys. Chem. C., v. 112 (13), p. 4986-4990 (2007)
55. A. Noy Strength in numbers: Probing and understanding intermolecular bonding with Chemical Force Microscopy, Scanning, invited article for a special issue on Scanning Probe Microscopy, v. 30 (2), p. 96-105. Cover Article (2007)
54. A. Noy, H.-G. Park, F. Fornasiero, J. K. Holt, C. P. Grigoropulous, O. Bakajin Nanofluidics in Carbon Nanotubes Nano Today, v.2(6), p. 22-29, invited review, Cover Article (2007)
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53. S-C. J. Huang, A. B. Artyukhin, J. A. Martinez, D. J. Sirbuly, Y. Wang, J-W. Ju, P. Stroeve, A Noy Formation, Stability, and Mobility of One-Dimensional Lipid Bilayers on Polysilicon Nanowires, Nano Letters, v.7(11); p. 3355-3359 (2007)
52. R. W. Friddle, M. C. LeMieux, G. Cicero, A. B. Artyukhin, V. V. Tsukruk, J. C. Grossman, G. Galli, A. Noy Single Functional Group Interactions with Carbon Nanotube Sidewalls, Nature Nanotechnology, v.2(11), p. 692-697 (2007)
51. A. B. Artyukhin, M. Stadermann, P. Stroeve, O. Bakajin, A. Noy Fabrication and Characterization of Suspended Carbon Nanotube Devices in Liquid, Int. J. Nanotechnology, v.5(4/5), p. 488-496 (2008). Invited article for a special issue on Nanosensors
50. R. W. Friddle, T. A. Sulchek, H. Albrecht, S. J. De Nardo, A. Noy Counting and breaking individual biological bonds: Force spectroscopy of tethered ligand-receptor pairs Current Nanoscience, v. 3(1), p. 41-48 (2007); invited review for a special issue on Nanomechanics of Organic and Inorganic Materials
49. A. B. Artyukhin, M. Stadermann, R. W. Friddle, P. Stroeve, O. Bakajin, A. Noy Controlled Electrostatic Gating of Carbon Nanotube FET Devices, Nano Letters, v. 6, p. 2080-2085 (2006)
48. M. Stadermann, A. D. McBrady, B. A. Dick, V. Reid, A. Noy, R. E. Synovec, O. Bakajin, Ultra-fast gas chromatography on single-wall carbon nanotube stationary phases in microfabricated channels, Analytical Chemistry, v. 78, p. 5639-5644, (2006)
47. A. Noy Chemical Force Microscopy of Chemical and Biological Interactions, Surf. Interface Analysis, v. 38(11), p. 1429-1441 (2006), invited article
46. T.A. Sulchek, R.W. Friddle, A. Noy Strength of Multiple Biological Bonds, Biophys. J., v. 90, p. 4686-4691 (2006)
45. J.K. Holt, H.-G. Park, Y. Wang, M. Stadermann, A.B. Artyukhin, C. Grigoropulous, A. Noy, O. Bakajin Fast Mass Transport Through Sub-2 nm Carbon Nanotubes, Science, v. 312(5776), p. 1034-1037 (2006) Cover Article
• #1 “Hot” paper in Chemistry, July 2008 (Essential Science Indicators, ISI)
• Highlighted by Chemical&Engineering News (US), 84, 9 (2006)
• Google Scholar “classic paper” in Nanotechnology field (2017)
44. T.A. Sulchek, R.W. Friddle, K. Langry, E. Lau, H. Albrecht, T.V. Ratto, S.J. DeNardo, M. Colvin, A. Noy Dynamic Force Spectroscopy of Parallel Individual Mucin1-Antibody Bonds, Proc. Natl. Acad. Sci. USA.,v. 102 (46), p. 16638-16643 (2005)
43. S.-C. Huang, A.B. Artyukhin, Y. Wang, J.-W. Ju, P. Stroeve, A. Noy Persistence Length Control of the Polyelectrolyte Layer-by-Layer Self-Assembly on Carbon Nanotubes J. Am. Chem. Soc., v. 127 (41), p.14176-14177 (2005)
42. H. N. Chapman, A. Barty, S. Marchesini, A. Noy, C. Cui, M. R. Howells, R. Rosen, H. He, J.C.H. Spence, U. Weierstall, T. Beetz, C. Jacobsen, D. Shapiro High-resolution
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ab initio three-dimensional X-ray diffraction microscopy, J. Opt. Soc. Am. A, v.23 (5), p. 1179-1200 (2006)
41. A.B. Artyukhin, A. Shestakov, J. Harper, O. Bakajin, P. Stroeve, A. Noy Functional One-Dimensional Lipid Bilayers on Carbon Nanotube Templates, J. Am. Chem. Soc., v. 127(20), p.7538-7542 (2005); article covered as Research News in Materials Today
40. D.V. Vezenov, A. Noy, P.D. Ashby Chemical Force Microscopy: Probing Chemical Origins of Interfacial Forces and Adhesion, J. Adh. Sci. Tech., v. 19, p. 313-364 (2005); invited review
39. J. Holt, A. Noy, T. Huser, D. Eaglesham, O. Bakajin Fabrication of a Carbon Nanotube-Embedded Silicon Nitride Membrane for Studies of Nanometer-Scale Mass Transport Nano Letters, v. 4, p. 2245-2250 (2004)
38. A. Noy Direct Determination of the Equilibrium Unbinding Potential Profile for a Short DNA Duplex from Force Spectroscopy Data Appl. Phys. Lett., v.85(20), p. 4792-4794 (2004)
37. Hau-Riege, S. P.; Szoke, H.; Chapman, H. N.; Szoke, A.; Marchesini, S.; Noy, A.; He, H. F.; Howells, M.; Weierstall, U.; Spence, J. C. H., SPEDEN: reconstructing single particles from their diffraction patterns, Acta Crystallographica Sect. A, v. 60, 294-305 (2004)
36. R.W. Friddle, J.E. Klare, S.S. Martin, M. Corzett, R. Balhorn, E.P. Baldwin, R.J. Baskin, A. Noy Mechanism of DNA compaction by Yeast Mitochondrial Protein Abf2p, Biophys. J., v. 86, p. 1632-1639 (2004)
35. J.K. Holt, H.G. Park, O. Bakajin, A. Noy, T.R. Huser, D. Eaglesham, Carbon Nanotube Based Membranes: A Platform for Studying Nanofluidics IEEE Nanotech Symp. Proc.; Munich, Germany, (2004)
34. J.K. Holt, H. Park, O.Bakajin, A. Noy, T. Huser, and D. Eaglesham Carbon Nanotube Based Permeable Membranes Mat. Res. Soc. Symp. Proc., v. 820 (2004)
33. A.B. Artyukhin, O. Bakajin, P.Stroeve, A. Noy Layer-by-Layer Electrostatic Self-Assembly of Polyelectrolyte Nanoshells on Individual Carbon Nanotube Templates, Langmuir, v.20, p. 1442-1448 (2003)
32. L.R. Brewer, R. W. Friddle, A. Noy, E.P. Baldwin, S.S. Martin, M. Corzette, R. Balhorn, R.J. Baskin Packaging of Single DNA Molecules by the Yeast Mitochondrial Protein Abf2p Biophys. J., v. 85, p. 25192524 (2003).
31. Bakajin, O., Ben-Barak, N., Peng, J., Noy, A. Carbon nanotube based microfluidic elements for filtration and concentration, Micro Total Analysis Systems, Squaw Valley, CA, Transducers Research Foundation.(2003)
30. S. Marchesini, H. He, H. Chapman, S. Hau-Riege, A. Noy, M. Howells, U. Weierstall, J.C.H.Spence X-ray image reconstruction from a diffraction pattern alone, Phys. Rev. B.,v.68, p.140101(R) (2003)
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29. H. He, S. Marchesini, M. Howells, U. Weierstall1, H. Chapman, S. Hau-Riege, A. Noy, J.C.H.Spence Inversion of X-ray diffuse scattering to images using prepared objects, Phys. Rev. B., v. 67, P. 174114 (2003)
28. D. V. Vezenov, A. Noy, C. M. Lieber Effect of solvent induced adhesion changes on the interfacial shear strength between self-assembled monolayers, J. Adhesion. Sci. Tech. v. 17, p. 1385-1401 (2003)
27. S. Zepeda, Y. Yeh, A. Noy, Determination of energy barriers for intermolecular interactions by variable temperature dynamic force spectroscopy, Langmuir, v.19, p.1457-1461 (2003); invited contribution
26. A. Noy, T.R. Huser A combined force and photonic probe microscope with single molecule sensitivity, Rev. Sci. Instr., v.74, p.1217-1221 (2003)
25. A. Noy, S. Zepeda, C.A. Orme, Y. Yeh. J. J. De Yoreo, Entropic barriers in nanoscale adhesion studied by variable temperature chemical force microscopy, J. Am. Chem. Soc., v.125, p.1356-1362 (2003)
24. B. L. Weeks, J. Camarero, A. Noy, A. E. Miller, L. Stanker, J. J. De Yoreo, A Microcantilever-Based Pathogen Detector, Scanning, v.25, 297299 (2003)
23. A. Noy, A.E. Miller, J. E. Klare, B. Woods, B.L. Weeks, J.J. De Yoreo, Fabrication of luminescent nanostructures by dip-pen nanolithography, SPIE Proceedings, v.4809, 249-254 (2002)
22. B. L. Weeks, A. Noy, A.E. Miller, J. J. De Yoreo, The effect of dissolution kinetics on feature size in dip-pen nanolithography, Phys. Rev. Lett., v. 8825, U85-U88 (2002)
21. A. Noy, A.E. Miller, J. E. Klare, B. Woods, B.L. Weeks, J.J. De Yoreo, Fabrication of luminescent nanostructures and polymer nanowires using dip-pen nanolithography, Nano Letters, v.2, 109-112 (2002)
20. C.A. Orme, A. Noy, A. Wierzbicki, M. T. McBride, M. Grantham, H.H. Teng, P.M. Dove, J.J. DeYoreo Selective Binding of Amino Acids to the Atomic Steps of Calcite Creates Chiral Structures, Nature, v.411, p.775-779 (2001)
19. A. Shestakov, J. Milovich, A. Noy Using Pseudo-Transient Continuation and the Finite Elment Method to Solve the Nonlinear Poisson-Boltzmann Equation. J. Colloid. Interfac. Science, v.247, p. 62-79 (2002)
18. A. Noy, D. V. Vezenov, C. M. Lieber Chemical Force Microscopy. Ann. Rev. Mater. Res., v.27, p.381-421 (1997), invited review
17. A. Noy, D. V. Vezenov, J. F. Kayyem, T. J. Meade, C. M. Lieber Stretching and Breaking Duplex DNA by Chemical Force Microscopy. Chemistry & Biology, v.4, p.519-527 (1997)
16. A. Noy, C. H. Sanders, D. V. Vezenov, S. S. Wong, C. M. Lieber Chemically Sensitive Imaging in Tapping Mode by Chemical Force Microscopy: Role of Tip-Sample Adhesive Interactions in Phase Lag Contrast, Langmuir, v.14, p.1508-1511 (1998)
• Front Cover Article
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15. A. Noy, C. D. Frisbie, L. F. Rosznyai, M. S. Wrighton, C. M. Lieber Chemical Force Microscopy: Exploiting Chemically Modified Tips to Quantify Adhesion, Friction and Functional Group Distributions in Molecular Assemblies. J. Am. Chem. Soc., v.117, p.7943-7951 (1995)
14. D. V. Vezenov, A. Noy, L. F. Rosznyai, C. M. Lieber Force Titrations and Ionization State Sensitive Imaging of Functional Groups in Aqueous Solutions by Chemical Force Microscopy. J. Am. Chem. Soc. v. 119, p.2006-2015 (1997)
13. D. V. Vezenov, A. Noy, C. M. Lieber Chemical and Solvent Effects in Adhesion Probed by Chemical Force Microscopy. Proceedings of the 20th Annual Meeting of Adhesion Society, 23 (1997).
12. C. D. Frisbie, L. F. Rosznyai, A. Noy, M. S. Wrighton, C. M. Lieber Functional Group Imaging by Chemical Force Microscopy. Science, v.265, p.2071-2074 (1994)
Books 11. Editor, Handbook of Molecular Force Spectroscopy, Springer,
2008 www.springer.com/978-0-387-49987-1.
Book performance metric: 14,500+ chapter downloads since 2009 From the reviews: "A broad overview of core principles of force spectroscopy is of
considerable utility and timeliness. Aleksandr Noy … has done an admirable job of assembling such an overview as well as providing insight into likely new directions of research. … a timely and useful summary of fundamental aspects of molecular force spectroscopy, and I believe it would make a worthwhile addition to any good scientific library. New research groups that are entering this field would be well advised to study this handbook … ." (Matthew F. Paige, J. Am. Chem. Soc., Vol. 130 (26), 2008)
“A series of ten chapters on various aspects of force spectroscopy, each written by an expert in the field. This book … aims ‘to present a series of topics that discuss fundamental concepts and basic methodology used to perform and understand force spectroscopy experiments and illustrate them using examples from current and past research.’ This work would represent a good introduction to the area for anyone wishing to know more about this increasingly important subject. Summing Up: Highly recommended. Upper-division undergraduate through professional collections." (A. Fry, CHOICE, Vol. 45 (10), June, 2008)
Book Chapters 10. A. Noy, M. Wanunu Nanofluidic Transport and Sensing in Biological and Artificial
Nanopores in An Introduction to Single Molecule Biophysics, Ed. Yu. Lyubchenko, Taylor & Francis (2018).
9. J.B. In, A. Noy Nanotechnology’s Wonder Material: Synthesis of Carbon Nanotubes, in Hierarchical Nanostructures for Energy Devices, Eds. S.C. Ko, C.P. Grigoropoulos, RSC Publishing (2014).
8. A. Noy, A. B. Artyukhin, S.-C. Huang, J. A. Martinez, N. Misra Functional Integration of Membrane Proteins with Nanotube and Nanowire Transistor Devices, in Bioconjugation Protocols: Strategies and Methods, Methods in Molecular Biology , Ed. S.Mark, Springer Science+Business Media, LLC (2011).
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7. O. Bakajin, A. Noy, F. Fornasiero, C. P.Grigoropoulos, J. K. Holt, J. B. In, S. Kim, H. G. Park Nanofluidic Carbon Nanotube Membranes: Applications for water purification and desalination, p. 77-96, in Nanotechnology for Water Quality, Eds.: M. Diallo, J. Duncan, N. Savage, R. Sustich, A. Street; William Andrew Publishers, (2009).
6. T. A. Sulchek, R. W. Friddle, A. Noy Counting And Breaking Single Bonds: Dynamic Force Spectroscopy In Tethered Single Molecule Systems in Handbook of Molecular Force Spectroscopy, Ed.: A. Noy, Springer (2008).
5. A. Noy, D. V. Vezenov, C. M. Lieber Chemical Force Microscopy 1: Nanoscale Probing Of Fundamental Chemical Interactions in Handbook of Molecular Force Spectroscopy, Ed.: A. Noy, Springer (2008).
4. D. V. Vezenov, A. Noy, C. M. Lieber Chemical Force Microscopy 2: Interactions in Complex Molecular Assemblies, in Handbook of Molecular Force Spectroscopy, Ed.: A. Noy, Springer, (2008).
3. A. Noy Interactions at Solid-Liquid Interfaces, in From fluid-solid interfaces to nano-structural engineering, Ed.: J. J. DeYoreo and X.-Y. Liu, Plenum/Kluwer Academic, (2004).
2. B. L. Weeks, A. Noy, A. E. Miller, J. E. Klare, B. W. Woods, J. J. De Yoreo Dip-Pen Nanolithography Using MHA and Optical Inks, in Dekker Encyclopedia of Nanoscience and Nanotechnology, p. 923-931, Marcel Dekker Publishers (2004)
1. D. V. Vezenov, A. Noy, C. M. Lieber Probing and Imaging interactions Between Functional Groups in Scanning Probe Microscopy in Polymers, v.694, ACS Symposium Series ACS, Ch.19 (1998)
Patents Issued patents: 1. C. L Lee, A. Noy, S. Swierkowski, K. Fisher, B. W. Woods Carbon nanotube array
based sensor. US 6,946,851, The Regents of the University of California, Oakland, CA., Iss. Sept. 20, 2005
2. O. Bakajin, A. Noy Microfluidic sieve using intertwined, free-standing carbon nanotube mesh as active medium US 7,290,667, The Regents of the University of California, Oakland, CA, Iss. Nov. 6, 2007
3. A. Noy, O. Bakajin, A. Artyukhin Lipid Bilayers on Nano-Templates Lawrence Livermore National Security, LLC, US 7,569,850. Iss. Aug. 4, 2009
4. A. Noy, O. Bakajin, S. Letant, M. Stadermann, A. Artyukhin Lipid Nanotube or Nanowire Sensor, US 7,544,978 B2, Lawrence Livermore National Security, LLC, Iss. June 9, 2009
5. O. Bakajin, J. Holt, A. Noy and H.-G. Park Membranes for Nanometer-Scale Fast Mass Transport, US 8,038,887, Lawrence Livermore National Security, LLC. Iss. Oct. 18, 2011
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6. R. Revanur, I.-J. Roh, J. E. Klare, A. Noy, O. Bakajin Thin Film Composite Membranes for Forward Osmosis and Their Preparation methods, US 8,920,654, Porifera, Inc., Iss. Dec 30, 2014.
7. O. Bakajin, A. Noy, F. Fornasiero, H.-G. Park, J. Holt, S. Kim Membranes with Functionalized Carbon Nanotube Pores For Selective Transport, US,8,940173 B2, Lawrence Livermore National Security, LLC, Iss. Jan 27, 2015.
8. V. Lulevich, O. Bakajin, J. E. Klare, A. Noy Preparation of aligned nanotube membranes for water and gas separation applications, US 9,227,360, Porifera, Inc., Iss. Jan 5, 2016.
9. R. Revanur, V. Lulevich, I.-J. Roh, J. E. Klare, S. Kim, A. Noy, O. Bakajin Membranes
having aligned 1-D nanoparticles in a matrix layer for improved fluid separation US US 9216391 B2, Porifera, Inc., Iss. Dec 22, 2015.
Provisional applications: 10. A. Noy, J. Geng, J. Zhang, V. Frolov Carbon nanotube trans-membrane channels
• Science@the Interface Symposium, University of Chicago, Chicago, IL, June 2016
• Royal Society Discussion Meeting on Biological Membrane Pores, London, UK, June
2016
• Connecting with Biology: Electronic Biology-Materials Symposium, University of
Nottingham, Nottingham, UK, July 2016
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• Condensed Matter Physics Seminar, University of California Santa Cruz, CA, October
2016
• Research seminar, National Cancer Institute (NCI), Frederick, MD, December 2016
• Massachusetts Institute of Technology (MIT), Cambridge, MA, July 2017
• IEEE NANO 2017, Pittsburgh, July 2017
• Division Seminar, LLNL, Livermore, CA, December 2017
• UC Merced Physics Colloquium, Merced, CA, February 2018.
• Materials Research Society, Spring 2018 Meeting, Symp. SM04 (“Understanding and Controlling the Structure and Function of Biomolecules at Material Interfaces”), Phoenix, AZ, 2018.
• Physical Chemistry Seminar, Department of Chemistry, University of Maryland, College Park, MD, September 2018.
• 2018-2019 Stanley Corrsin Memorial Lecture, Johns Hopkins Univ., Baltimore, MD, December 2018.
• 2019 North American Membrane Society (NAMS) Annual Meeting, Pittsburgh, PA, May 2019
Research Interests • Nanofluidics: molecular transport in carbon nanotube pores and 2D nanomaterials.
Enhanced water transport efficiency and ion selectivity in carbon nanotube pores. Next generation membranes and water purification technologies.
• Single-molecule biophysics: High-speed atomic force microscopy imaging of biomolecules and biomaterials. Intermolecular interactions and force spectroscopy.
Honors and Awards • 2018-19 Stanley Corrsin Memorial Lectureship (Johns Hopkins University) • R&D 100 Award for Ultrapermeable Carbon Nanotube Membranes (2010)
Also selected as Editor’s Choice by R&D Magazine. (2010)
• Most cited paper in the field of Chemistry (Holt et al., Science, 2006) as determined by Science Watch in June 2008
• Frost & Sullivan Emerging Technology of the Year Award (2006)
• Multiple LLNL Awards for Excellence in Publication, LLNL (2005, 2006, 2008, 2014, 2015, 2016, 2017)
• LLNL Science and Technology Award (2001)
• E. O. Lawrence Fellowship, LLNL (05/1998-08/2001)
• Fannie and John Hertz Foundation research grant (1995)
• Hertz Fellowship Finalist (1995)
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Teaching • UC Merced, CORE 090X 006
o Freshman Seminar “Scientific Discovery: Myth and Reality” Discussed the nature of scientific research illustrated with topics in contemporary biophysics
• UC San Francisco, OCS221 o Guest lecture “Bioelectronics” (03/2016, 03/2017, 02/2018)
Professional Memberships • Biophysical Society
• Materials Research Society
• American Chemical Society
• American Physical Society
Professional Activities 2016
Organizer, 3rd Asilomar Bioelectronics Symposium, Pacific Grove, CA (Sept. 2018)
2016
Organizer, 2nd Asilomar Bioelectronics Symposium, Pacific Grove, CA (Sept. 2017)
2015-current
International Advisory Board Member, International Winter School of Bioelectronics (BioEL, www.bioel.at).
2014-2016
Founding organizer, 1st Asilomar Bioelectronics Symposium, Pacific Grove, CA (Sept. 2016)
2015-2016 Organizer, International Winter School of Bioelectronics, BioEL-2016, Kirchberg, Austria (March 2016)
2015-current Foreign Editorial Board Member, Nanotechnologies in Russia, Springer (inactive)
2014-current
Board Member of the User Executive Committee, The Molecular Foundry, LBNL 2014 Review panel member, Biomolecular Materials External Review of Materials and
Chemistry S&T Program, Naval Research Laboratory, Washington, DC
2010 Session Chair, ACS Spring Meeting 2010, San Francisco, CA
2009: Program Committee Member, 16th International Conference on Crystal Growth, Beijing, China, 2010
2004: Symposium Organizer (Nanoscale Probing of Intermolecular Interactions) American Chemical Society Spring Meeting 2004, Anaheim, CA
2001: Local organizing committee member, 6th International conference on atomically controlled surfaces, interfaces and nanostructures (ACSIN-6), Lake Tahoe, CA
2004: LLNL Physical Biosciences Institute, Internal Advisory Board Member
Research Proposal Review Activities • Chair of the Proposal Review Panel for Imaging Facility, The Molecular Foundry,
Lawrence Berkeley National Laboratory, Berkeley, CA (2016) • Proposal Review Panel, The Molecular Foundry, Lawrence Berkeley National
Laboratory, Berkeley, CA (2008-pres) • Member, Center for Functional Nanostructures Proposal Review Panel (PRP),
Brookhaven National Laboratory, Upton, NY, 2-year term (2008-2010) • NSF NIRT Review Panel • NSF CBET Review Panel • NSF MRI Program (multiple proposals) • NSF SBIR Review Panel • DOE Office of Science: Basic Energy Sciences (multiple proposals) • Israel Science Foundation (ISF) (multiple proposals) • Netherlands Organization for Scientific Research (NWO) • Swiss National Science Foundation
Selected Journal Peer Review Activities • Science
• Nature Nanotechnology
• Nature Materials
• Nature Communications
• Proc. Natl. Acad. Sci. USA • Nano Letters • ACS Nano • Advanced Materials • Phys. Rev. Lett.
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• Journal of the American Chemical Society • Physical Review B. • Science Advances
