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8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Multi-disciplinary work on Video Analysis
Use of Information Technology for
Monitoring Pain in Patient Care
Rashid Ansari
Dept. of Electrical & Computer EngineeringUniversity of Illinois at Chicago
Work done with
Diana J. Wilkie, Chaired Professor in Bio-behavioral Health Sci.
and
Zhanli Chen, ECE PhD student
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Outline
Larger Context
Motivation for video analysis for pain
Framework for using Bio-behavioral models for
Automated Pain detection Past Work and Available Databases
Feature extraction and tracking using Active
Appearance Model (AAM)
Rule-based Action Unit Recognition Results
Conclusion
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Outline
Larger Context
Motivation for video analysis for pain
Framework for using Bio-behavioral models for
Automated Pain detection Past Work and Available Databases
Feature extraction and tracking using Active
Appearance Model (AAM)
Rule-based Action Unit Recognition Results
Conclusion
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
http://slidepdf.com/reader/full/ansari-automated-pain-detection-fit20111220 4/41
Larger Context
Information technology and healthcare
enterprises.
Electronic Health Record (EHR) systems
EHR ± Data Treasure Trove Need for multidisciplinary skills
Nature of EHR data
Goal: Need training in IT and Health disciplines ± ³clinician¶s big picture" of the patient¶s condition based on its current
EHR data, assisted by the analysis, mining, and visualization of
historical EHR data securely accessed in a privacy-preserving manner
from disparate EHR systems.
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Larger Context ± Excerpt from report of IEEE
Presidents http://dl.dropbox.com/u /2397114/IEEE_kam.pdf
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Larger Context ± Report of IEEE
Presidents
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Larger Context ± Report of IEEE
Presidents
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Larger Context ± EHR Training & Research for
Advances in Informatics (EHR-Train)
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Outline
Larger Context
Motivation for video analysis for pain
Framework for using Bio-behavioral models for
Automated Pain detection Past Work and Available Databases
Feature extraction and tracking using Active
Appearance Model (AAM)
Rule-based Action Unit Recognition Results
Conclusion
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Motivation for Automated Pain
Recognition
Behavioral observation ± important for assessing pain.
Many populations cannot communicate pain
± children,
± critically ill non-communicative patients,
± patients undergoing procedures,
± adults with dementia
Taskforce Position statement recognized use of Facial
Expression: ³Pain assessment in the nonverbal
patient: position statement with clinical practice
recommendations´.
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Motivation for Automated Pain
Recognition
Facial expression is behavioral indicator of
pain - characterized by the Facial Action
Coding System (FACS)1 Ekman-Friesen
FACS: Objective assessment in expression
analysis - facial Action Units (AUs)
AUs - single or combination muscular activity that produces changes in facial
appearance ± 44 AUs
9 Pain-related AUs (example)
AUs detected by FACS experts
[1]Ekman P, Friesen WV, Hager JC. New Version of the Facial Action Coding System:
The Manual. Salt Lake City, UT, USA: Research Nexus Division of Network Research
Information; 2002.
Photo Source: Kim Komenich, with permission.
Pain AUs: Injured soldier.
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Motivation for Automated Pain
Recognition
Facial expression is behavioral indicators of
pain - characterized by the Facial Action
Coding System (FACS)1 Ekman-Friesen
FACS: Objective assessment in expression
analysis - facial Action Units (AUs)
AUs - single or combination muscular activity that produces changes in facial
appearance ± 44 AUs
9 Pain-related AUs (example)
AUs detected by FACS experts
Facial expression coding using FACS - time
consuming, clinical use infeasible
[1]Ekman P, Friesen WV, Hager JC. New Version of the Facial Action Coding System:
The Manual. Salt Lake City, UT, USA: Research Nexus Division of Network Research
Information; 2002.
Photo Source: Kim Komenich, with permission.
Pain AUs: Injured soldier.
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Outline
Larger Context
Motivation for video analysis for pain
Framework for using Bio-behavioral models for
Automated Pain detection Past Work and Available Databases
Feature extraction and tracking using Active
Appearance Model (AAM)
Rule-based Action Unit Recognition Results
Conclusion
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Framework for Using FACS - detecting
Pain-related Action Unit
Table 1. Description and Muscular Basis of Selected Action Units for Pain Facial Expression
Action Unit Description Muscular Basis
4 eye brow lowerer depressor glabellae, depressor supercilii; corrugator supercilii
6 cheek raiser orbicularis oculi; pars orbitalis
7 eye lid tightener orbicularis oculi; pars palebralis
9 nose wrinkler levator labii superioris alaeque nasi10 upper lip raiser levator labii superioris; caput infraorbitalis
20 lip stretcher risorius
26 jaw drop masetter; temporal and internal pterygoid relaxed
27 mouth stretch pterygoids, digastric
43 eyes closed relaxation of levator palpebrae superioris
AU Source: Ekman & Friesen, 1978; with permission;
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Framework to use FACS ± feature
points to detect AUs (shape vertices)
66 vertices are first identified in the face image AUs are linked to these vertices or feature points
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Framework to use FACS: Key
Ingredients for Pain Recognition
Behavioral model for assessing pain ± FACS
AUs are linked to key facial feature points
Approach to use FACS in Video Analysis:
± Mark features in key frames and train a model
± Use model to extract feature points and track them
± Use rules to map features to Pain AUs for
detection and recognition
The above 3 items define tasks in AU recognition
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Framework to use FACS: Schematic of
Tasks for AU detection
Training Set
Labeling
Featureextraction and
tracking
Pain FacialExpression
Detection andRecognition
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Framework to Use FACS: Task I -
Semi-automated labeling
Some Key frames are labeled with 66 vertices along the featurecues in the face.
Marking vertices by hand is tedious
Some key vertices are first identified and the location of remaining
vertices is constrained by their relationship to the key vertices.
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Outline
Larger Context
Motivation for video analysis for pain
Framework for using Bio-behavioral models for
Automated Pain detection Past Work and Available Databases
Feature extraction and tracking using Active
Appearance Model (AAM)
Rule-based Action Unit Recognition
Results
Conclusion
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Past work and available databases
Research on automated expression recognition uses geometricfeatures referred to as the shapes of the facial components (eyes,
mouth, etc.) and appearance features including textures, wrinkles,
bulges, and furrows.
Most of the expression recognition methods are classifier-based built
from large training sets.
A rule-based approach was developed by Pantic et al68 for AUdetection using temporal dynamics of the feature points.
Past work focused on general expression recognition
Only recently has some effort been directed at detecting pain-related
facial expression. Lucey et al use an Active Appearance Model (AAM)
based method to extract features and used support vector machines
(SVM) for pain recognition from video achieves of patients with
shoulder pain (acute pain)
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Past work and available databases:
Existing Databases
Databases ± Cohn-Kanade facial expression database
most widely used database for facial expression
recognition.
± MMI facial expression database
contains both posed expressions and spontaneous
expressions of facial behavior.
± BU-3DFE database 3D range data of six prototypical facial expressions
± UNBC-McMaster Shoulder Pain Archive
Spontaneous expression caused by real pain
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Our Video Database of Lung Cancer
Patients
Our database has videos of 43 lung cancer patients -- 10-minute
video with the camera focusing on the face
Each 600-sec video is partitioned into 30 equal-sized segments
with 20 seconds per segment
Segments are reviewed and scored by three trained codersindependently.
An AU is scored in a video time slot only if at least two coders
agree on its presence.
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Outline
Larger Context
Motivation for video analysis for pain
Framework for using Bio-behavioral models for
Automated Pain detection Past Work and Available Databases
Feature extraction and tracking using Active
Appearance Model (AAM)
Rule-based Action Unit Recognition
Results
Conclusion
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Task II: Feature Extraction and Tracking -
Active Appearance Model (AAM)
AAM - parametric model of shape and texture, used in object
appearance modeling.
Shape model: n Eigen shapes Si plus the mean shape S0 .
Appearance model: m Eigen appearance Ai , plus the mean
Eigen texture A0
Goal of AAM: find parameters that minimize the error between
the observed image and synthesized image.
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Task II: AAM Modification - Coefficient
Partitioning Method
AAM employs a set of parameters to control the shape and texturevariation, which define a registration between a target image and a
reference template.
In the original model, each coefficient controls certain motion
(represented by one Eigen shape) of all vertices simultaneously in the
shape model.
Convergence problems can occur when the algorithm tries to fit
different feature components on the face when the facial change is
localized.
In order to extract the expression information accurately, more flexibility
is necessary for the deformation of the shape model.
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Task II: AAM Modification: Coefficient
Partitioning Method
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Task II: AAM Fitting results
Labeled Training Images of patient P16.
Result of synthesizing patient face using AAM fitting for patient P16 in video segment 18.
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Task II: AAM Modification: Coefficient
Partitioning Method
After processing all shape vertices are
available
Need to define rules to use vertices to
determine AU
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Outline
Larger Context
Motivation for video analysis for pain
Framework for using Bio-behavioral models for
Automated Pain detection Past Work and Available Databases
Feature extraction and tracking using Active
Appearance Model (AAM)
Rule-based Action Unit Recognition
Results
Conclusion
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Task III: Rule-Based Action Unit Recognition
The feature extraction for rule-based method: needs shapeinformation from the AAM fitting result.
Main idea: Define rules from information of the feature point position to
synthesize AUs as described in the FACS manual.
Temporal information of the feature points can enhance the capacity
and robustness in AU recognition Distance Parameter extraction
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Task III: Pain related Action Unit
(Recall)
Table 1. Description and Muscular Basis of Selected Action Units for Pain Facial
Expression
Action Unit Description Muscular Basis
4 eye brow lowerer depressor glabellae, depressor supercilii; corrugator
supercilii
6 cheek raiser orbicularis oculi; pars orbitalis7 eye lid tightener orbicularis oculi; pars palebralis
9 nose wrinkler levator labii superioris alaeque nasi
10 upper lip raiser levator labii superioris; caput infraorbitalis
20 lip stretcher risorius
26 jaw drop masetter; temporal and internal pterygoid relaxed
27 mouth stretch pterygoids, digastric
43 eyes closed relaxation of levator palpebrae superioris
AU Source: Ekman & Friesen, 1978; with permission;
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Task III: Recognition Rules
The rules listed in Table 2 use AU descriptions in the FACS manual (scoring AU
with intensity B)
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Task III: Visual Tracking Results
Plots of some tracked feature points in segment 18 of patient P16s video.
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Task III: Recognition Procedure using
time evolution
A Complete AU occurrence has 3 stages: Onset, Apex, Offset
Two sets of thresholds are used: Lower
threshold for Onset and Offset and higher
threshold for Apex (the trajectory should have an
amplitude to score intensity B)
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Schematic View of the system
Automated AU Recognition Method.
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Outline
Larger Context
Motivation for video analysis for pain
Framework for using Bio-behavioral models for
Automated Pain detection Past Work and Available Databases
Feature extraction and tracking using Active
Appearance Model (AAM)
Rule-based Action Unit Recognition Results
Conclusion
8/3/2019 Ansari Automated Pain Detection FIT2011!12!20
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Results
Due to the sparse appearance of AUs in the patient
video, we evaluate performance by examining the
agreement between the AUs detected by the
algorithm and those scored by experts.
Tested several video segments for four patients
containing different AU combinations.
We compared AUs recognized by the computer with
those scored by at least two human coding experts
We found f ull agreement in the case of the
segments investigated so far .
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Future Work
We will investigate all 43 patient videos. We areimproving the AAM fitting algorithm to make it more
robust.
Plan to new multi-view high-resolution patient video
dataset, so that we will get a better quality video tostudy the automated pain recognition system.
We will also extend our research to 3D accordingly to
better handle the rigid motion problem.
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Conclusion
Use of Information Technology for Monitoring Pain inPatient Care.
Multi-disciplinary work on Video Analysis
Information technology and healthcare enterprises -
Electronic Health Record (EHR) Need for training a future workforce with
multidisciplinary skills.
Behavioral observation ± important for assessing
pain. Translational research to use FACS to develop an
automated pain AU recognition system
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Thank You