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UNC LINEBERGER COMPREHENSIVE CANCER CENTER DONOR HONOR ROLL BEAT CANCER. INVEST IN PEOPLE. SEEK SCIENTIFIC SOLUTIONS. BUILD CLINICAL EXCELLENCE.
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Page 1: “When I grow up, I want to be an astronaut, an ... · Manager Laura Oleniacz, Science Communications Manager Claire Nickles, Development & ... Oncology Service Line Meghan McCann,

“When I grow up, I want to bean astronaut, an oncologist,and an artist. But right now I’m working as a secret agent!”

Charlotte Brinn6 years oldacute lymphoblastic leukemia

CAMPUS BOX 7295CHAPEL HILL, NC 27599-7295

Produced by UNC Lineberger Development & CommunicationsPlease direct comments to 919-966-7834 or email [email protected].

Editors: Kiecha Berzins, APR, Communications ManagerBill Schaller, Director, Communications & MarketingDesign: Leesa Brinkley

Non Profit OrgUS PostagePAIDChapel Hill, NCPermit No. 71

UNC LINEBERGER COMPREHENSIVE CANCER CENTER!"#$ % !"#& DONOR HONOR ROLL

BEAT CANCER.

INVEST IN PEOPLE. SEEK SCIENTIFIC SOLUTIONS.

BUILD CLINICAL EXCELLENCE.

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2 0 1 5 – 2 0 1 6 D O N O R H O N O R R O L L !"

UNC LINEBERGER ADMINISTRATION

Norman E. Sharpless, MD, Director ofUNC Lineberger

H. Shelton Earp, MD, Director, UNCCancer Care

Chad Ellis, PhD, Associate Director

Al Baldwin, PhD, Associate Director,Basic Research

Lisa A. Carey, MD, Associate Director,Clinical Research

Anne Menkens, PhD, AssistantDirector

Andrew Olshan, PhD, AssociateDirector, Population Sciences

Joseph S. Pagano, MD, DirectorEmeritus

Wendy Sarratt, DrPH, AssociateDirector

Thomas Shea, MD, Associate Director,Clinical Outreach

UNC Lineberger Program LeadersEthan Basch, MD, Cancer Preventionand Control

James Bear, PhD, Cancer Cell Biology

Lisa A. Carey, MD, Breast Cancer

Blossom Damania, PhD, GlobalOncology, Virology

Claire Dees, MD, Clinical Research

James Evans, MD, PhD, CancerGenetics

Stephen V. Frye, PhD, MolecularTherapeutics

Neil Hayes, MD, Clinical Research

Gary Johnson, PhD, MolecularTherapeutics

Terry Magnuson, PhD, Genetics

Andrew Olshan, PhD, CancerEpidemiology

Charles M. Perou, PhD, Breast Cancer

Nancy Raab-Traub, PhD, Virology

Kurt Ribisl, PhD, Cancer Prevention & Control

Jon Serody, MD, Immunology

Jenny Ting, PhD, Immunology

Melissa Troester, PhD, CancerPrevention and Control

Yue Xiong, PhD, Cancer Cell Biology

Development & CommunicationsMartin Baucom, Senior ExecutiveDirector of Development &Communications

Eli Jordfald, Senior Director of Major Gifts

Kelly Mansfield, Director ofDevelopment

Betsy Gentry-Bumm, Director of Annual Giving

Aime Mitchell, Director ofDevelopment Operations andStewardship

Jennifer Bowman, Director of Special Events

Bill Schaller, Director ofCommunications & Marketing

Kiecha Berzins, CommunicationsManager

Laura Oleniacz, ScienceCommunications Manager

Claire Nickles, Development &Communications Associate

Clinical Services at N.C. Cancer HospitalLisa A. Carey, MD, Chief of theDivision of Hematology andOncology and Physician in Chief, N.C. Cancer Hospital

David Ollila, MD, Associate Physicianin Chief, N.C. Cancer Hospital

Matt Milowsky, MD, Clinic MedicalDirector, N.C. Cancer Hospital

Marlene Ri!in, RN, Senior VicePresident for Women's and Children'sand Oncology Service

Ian Buchanan, MD, Associate VicePresident for UNC Health Care’sOncology Service Line

Meghan McCann, RN, MSN, NE-BC,Director Oncology Services

FEATURES

INSIDE

Fox fights bone marrowcancer and winsSuperior Court Judge Carl Fox isback on the bench after a cordblood transplant saved his life.

8 16

26 36

The Williams major giftadvances cancer research“We have faith scientists willunlock mysteries behind thisdisease.”

Clinical trials lead to new treatmentsAmy Charney didn’t let breastcancer stop her from reachingthe finish line.

Opening up the lines of communicationBasch lab receives $5.45 million to study patient-reportedoutcomes.

5 Director’s Message 6 Section One: Invest in People to Find a Cure14 Section Two: Venture to Seek Scientific Solutions 24 Section Three: Build Clinical Excellence –

Research and Care to Advance Hope 34 Section Four: Unite Across Population Sciences

to Beat Cancer 44 Major Gifts and Pledges46 Memorial Tributes 48 Honor Roll Donors 52 The Berryhill Society 53 Our Comunity

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“Cutting edge science, marvelous, humane clinical care, andtransformative training: those are the things I think we doreally well. That’s what comes to mind when I think of whatUNC Lineberger is all about.” Norman E. Sharpless, MD

UNC Lineberger Director

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! U N C L I N E B E R G E R C O M P R E H E N S I V E C A N C E R C E N T E R

Ashley, neuroblastoma,non-Hodgkin’s lymphoma

Elaine, breast cancer

Eric, lymphoma Trent, natural killer cell leukemia

Rengate, head and neck, lung,and prostate cancer

Coach Hatchell, leukemia Jo Anne, ovarian cancer

Cancer started this fight. We will finish it.

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Norman E. Sharpless, MDDirector, UNC Lineberger Comprehensive Cancer Center

2 0 1 5 – 2 0 1 6 D O N O R H O N O R R O L L !

Inventor and Apple, Inc. co-founder Steve Jobs once said, “I want to put a ding in the universe.” As aresearcher and physician, that’s how I feel about cancer. I truly believe our work at UNC LinebergerComprehensive Cancer Center is making the kind of significant impact to which Jobs was referring,and your generosity helps make that happen. Day in and day out, our team strives to unlock themysteries of a disease that claims nearly 600,000 lives in the U.S. annually. But we couldn’t do it without you.

If there’s a song title that describes this past year at UNC Lineberger, it’s “On the Road Again.” Duringthe last twelve months, we’ve taken our cancer center’s powerful story across state lines to places likePalo Alto, California, a city teaming with high-technology companies seeking out early investmentopportunities. We’ve also shared our work with new groups of potential donors in Palm Beach, Florida,who, like you, know a good investment when they see it and want to be a part of an organization thatcan make the world a better place for generations to come.

Cancer is a costly disease, and new philanthropic commitments will be key to the future success ofUNC Lineberger. We recently set a preliminary fundraising goal of $200 million from private sourcesover an eight-year period as part of the university’s larger capital campaign. That goal representssignificant growth in yearly fundraising results and is befitting an institution of our caliber. Thanks toyou, our fundraising is pushing the pace and keeps UNC Lineberger on its amazing trajectory.

This year’s Donor Honor Roll is filled with inspiring stories of scientific discovery, as well as thrillingaccounts of hope, survival and appreciation from patients and families who have become a part of ourgrowing Lineberger family. We’ve also featured some of the 6,520 donors who helped us raise morethan $29 million during the last fiscal year – a truly amazing feat. It’s taken all of these people to make UNC Lineberger the top cancer center in North Carolina, and I’m personally grateful to each and every one.

With thanks for all that you do –

A message from our director

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!

Invest into finda

S E C T I O N O N E

Julie Blatt, MD

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npeoplea cure

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! U N C L I N E B E R G E R C O M P R E H E N S I V E C A N C E R C E N T E R

I N V E S T I N P E O P L E T O F I N D A C U R E

Superior Court Judge CarlFox has been a fixture inOrange and ChathamCounty courtrooms since1978, when he first began

his law career as an assistant districtattorney. “After nearly 40 years ofpracticing law in the samecommunity, I’ve made many, manyfriends and a few enemies along theway,” Fox says, laughing as he recallssome of his high-profile cases.“Overall, it’s an extremely rewardingcareer and a real honor to serve.”

But in the spring of 2015, Foxworried that he might not be able togo back to the bench at all. Formonths he’d been losing weight, hetired easily, and his leg bothered himso much he’d begun limping. Hisinternist, Tim Carey, MD, orderedlab work and found that Fox’splatelets were low. He was admittedto the hospital. “After more tests, Iwas diagnosed with myelodysplasticsyndrome (MDS), a form of bonemarrow cancer, and I knew it wasn’t good.”

Within weeks, Fox was transferred tothe N.C. Cancer Hospital under thecare of Josh Zeidner, MD. GivenFox’s diagnosis of MDS and severeblood count abnormalities, Zeidner began treatment with achemotherapy called Azacitidineand referred Fox to see ThomasShea, MD, to consider a bonemarrow transplant. Shea, a UNCLineberger member, professor ofHematology and Oncology at theUNC School of Medicine, anddirector of the UNC Bone Marrowand Stem Cell TransplantationPrograms, says Fox su!ered frombone marrow failure, meaning hisbone marrow was not producing redblood cells, white blood cells, orplatelets e!ectively.

“In high-risk forms of MDS, likeCarl’s case, a bone marrowtransplant is recommended andrepresents the only chance toprovide a cure for this disease,” saysShea. “Unfortunately, when weresearched the national bone

marrow donor registries, there wasno bone marrow match for Carl. ”

While Fox initially tolerated thechemotherapy treatment well, hisblood counts did not improve. Thenhe developed complications of MDS,including multiple hospitalizationsfor infections, and it was clear thechemotherapy was not helping hisdisease. However, there was anothertreatment option: a cord bloodtransplant. This type of blooddonation is collected from theplacenta and umbilical cord after ababy’s birth. The cells are thentested, frozen, and stored as a cordblood unit at a public cord bloodbank for future use.

Shea was thrilled to find two cordblood units on the registry that werea close match for Fox. The units wereimmediately shipped from New Yorkto North Carolina, and Fox’s medicalteam began preparing him for thetransplant. This meant completelywiping out his immune system withchemotherapy and full body

FOX FIGHTS BONE MARROW CANCER AND WINS

Judge Carl Fox and Julia Smith

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2 0 1 5 – 2 0 1 6 D O N O R H O N O R R O L L !

radiation so the new, healthy cord bloodstem cells could be infused and beginreproducing on their own. On September30, 2015, Shea performed Fox’s cordblood transplant.

After Carl’s transplant, he su!eredsignificant weight loss,” says Zeidner, aUNC Lineberger member and assistantprofessor of Hematology and Oncologyat the UNC School of Medicine. “Butwith good nursing care, he began torecuperate, steadily putting on poundsand regaining his strength. He wasdischarged after a lengthy stay in thebone marrow transplant unit.

Over the following months, with rest andTLC from his long-time partner, JuliaSmith, Fox continued his recovery. Hiswhite blood cell and platelet counts wentup; the cord blood transplant had been asuccess. Fox returned to the courtroomon July 11, 2016.

“I’m in complete remission, I’m back atwork, and I’m living my life, thanks to thecare I received at UNC Lineberger,” saysFox. “I’m so grateful to have a world-classcancer center right here in my own backyard, filled with people like Dr. Shea andDr. Zeidner who go to great lengths tohelp and heal their patients. Words can’texpress my gratitude.”

SHEA NOMINATED FOR PROFESSORSHIPPrivate funds to support both established faculty and juniorresearchers are critical as we develop the best and brightestphysicians here at UNC. We are grateful to The John William PopeFoundation for its $1 million gift to UNC Lineberger to fund cancerresearch and treatment through the creation of the John WilliamPope Distinguished Professorship in Cancer Research.

Thomas Shea, MD, has been has been nominated to be the firstrecipient of this professorship. Shea was one of the late John WilliamPope’s physicians when he was treated for cancer in 2006 and is aninternational leader in the care of patients with hematologicmalignancies such as leukemia, lymphoma, and multiple myeloma.

“I am humbled that the Pope familychose to make such a significant gift inmy honor and pleased to be consideredas the first recipient,” Shea said. With this professorship, Shea hopes to expand research surroundinghematologic malignancies and lay the foundation for Lineberger’scontinued excellence in transplant and blood cancer initiatives.

Josh Zeidner, MD

Thomas Shea, MD

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I N V E S T I N P E O P L E T O F I N D A C U R E

The Seed Grant Programat UNC Linebergergives skilledresearchers theopportunity to find

answers to some of cancer’s biggestchallenges and develop promisingnew concepts for basic cancerresearch, clinical care, prevention,early detection and survivorship. Anincreasingly competitive fundingenvironment has magnified the needfor and impact of investments in thistype of innovative research.

For UNC Lineberger physicians andscientists, seed grants not only yieldearly results; they also help developthe ideas that grow into large,federally funded projects aimed attransformative breakthroughs incancer care.

Serody: “Grants were pivotal”Jonathan Serody, MD, had justcompleted a fellowship in clinicalbone marrow transplantation at FredHutchinson Cancer Research Centerin Seattle, Washington, when he was

o!ered a faculty position in theDepartment of Medicine at UNC.“My wife did her undergraduatework at UNC, and I really liked thearea,” says Serody. “We agreed thatChapel Hill would be a great place toraise our children, so in 1993, wemoved across the country andbecame Tar Heels. We’ve been hereever since.”

Funded by privatesupport and statefunds, seed grantshave helped UNCbecome a top 10institution forresearch funding.In his early days at UNC, Serody wasthe recipient of several smallresearch grants that proved to bepivotal in his career. “Oftentimes, ifyou’re just starting out in research oryou’re new to an area, a small grantcan help fund experiments andproduce enough data to spur larger

investments from other institutionsand organizations. There’s a realmultiplying e!ect,” explains Serody.“Unfortunately, even if a researcher’sfindings are novel, evengroundbreaking, if they don’t haveenough money to pay for theirresearch, it’s di"cult for them tovalidate their work to potentialfinancial suitors.”

Serody is now the associate directorof translational science at UNCLineberger and a medical oncologistin the UNC Lineberger Leukemiaand Lymphoma MultidisciplinaryCare Program. When asked why he’sstayed at UNC Lineberger for 26years, Serody says his family has putdown roots here, and he’s had theopportunity to work with someamazing people. “But to be asuccessful researcher, that’s notenough,” Serody explains. “I’vestayed here at UNC because of theircommitment to supportingadvanced research. It has beencritical to my work and the resultingaccomplishments.”

SEED GRANTS YIELD RETURN ON INVESTMENT

Jonathan Serody, MD

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MONTY AND NANCY WHITEPutting down roots, planting the seeds of discovery

Monty and NancyWhite met asundergraduates atUNC-Chapel Hill,and like most Tar

Heels, the couple’s devotion to theplace we call “Blue Heaven” hasbecome stronger through the years.“Even after we graduated fromCarolina in 1970, we found ourselvescoming back time and time again,attending sporting events andenjoying the company of goodfriends,” says Nancy. “We have rootshere. It’s always been our home-away-from-home.”

Monty grew up in Raleigh, workingin his grandfather’s automotive partsbusiness during summer vacationsand in the years following hisgraduation from UNC. The familyeventually sold the automotive partsbusiness to CARQUEST, and then in1987, he and his brother Bill, also aUNC alum, began a real estatecompany called White OakCommercial. “That’s when Nancyand I began investing more of ourtime, energy and resources into theacademic and research needs of theuniversity.”

For years, Nancy has been active onvarious UNC boards, including TheInstitute for the Environment andthe College of Arts and Sciences. In1998, Monty and Nancy were askedto join the UNC Lineberger Board ofVisitors, and they happily accepted

the invitation. “Cancer has directlya!ected our lives in very personalways,” says Nancy. “Monty’s fatherdied of lung cancer when he was 71,and I lost my mother to the samedisease when she was just 69. Myfather passed away from melanomaat age 93. As you can imagine, UNCLineberger’s cancer research is acause near and dear to our hearts.”

In 2003, Monty and Nancyestablished the White Seed GrantFund, which was designed to provideseed grant support for UNCLineberger faculty research. Thecouple agrees it is one of thesmartest investments they’ve evermade.

“When Nancy and I attendLineberger board meetings, we getexcited hearing about cutting edgetechnology, new clinical trials andlives being saved,” says Monty. “Werealize there is hope. Researchers andphysicians are making progress infighting this horrible disease, andscientific breakthroughs arehappening right here in Chapel Hill.We want to be a part of that success.One day our seed grant fund couldhelp spark a discovery that leads to acure. That is money well-spent.”

Monty and Nancy White

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UNC Linebergerhosted its 2nd BlueRibbon Gala onSeptember 18, 2015,gathering more

than 400 people to celebrateadvancements in cancer care atUNC. A select few were honored atthe black-tie event who have madesignificant contributions to UNCLineberger in the fight againstcancer, including Nicholas Valvano,president emeritus of The V Foundation for Cancer Research.

Valvano is the eldest brother of thelate N.C. State University basketballcoach Jim Valvano, who foundedThe V Foundation for CancerResearch after being diagnosed withcancer at the young age of 46.Nicholas served as chief executiveo!cer of The V Foundation for 13years (1999-2012) and has been amember of the Board of Directorssince its inception. Under hisleadership, The V Foundation

established relationships withseveral cancer centers nationwide –including UNC Lineberger – andawarded more than $100 million ingrants across 38 states. TheFoundation proudly awards 100percent of direct cash donations tocancer research and relatedprograms, continuing CoachValvano’s legacy and his inspiringwords, "Don't give up...Don't evergive up!"

Perou awarded V FoundationGrant, matched by others Chuck Perou, PhD, a UNCLineberger member and world-renowned researcher in the field ofgenomics and breast cancer, washonored to receive a 2015 VFoundation “Partners in ExcellenceCollaborative Grant” for $250,000.The award was matched by a$250,000 gift from long-time donorsand UNC Lineberger Board ofVisitors members Wally and

Lil Loewenbaum and Neill and LindaCurrie, for a total of $500,000 incancer research funding.

“We are extremely grateful for thisfunding, which will allow us topursue a novel form of researchcalled immunogenomics,” explainsPerou. “By approaching the immunesystem from a genomics perspectiveusing DNA and RNA sequencing, wecan now sample tumors and studythe immune response in hundreds ofindividual patients at a personalizedlevel never seen before. This is all apart of our quest to harness thepower of the immune system to fighttumors.”

Perou says this type of matching giftprovides researchers greaterfreedom to pursue high risk, highreward translational research, asopposed to government-basedfunding. It is this type of intellectualfreedom that drives innovation andis most likely to result in novelfindings of high importance thatdirectly a"ect cancer patients.

I N V E S T I N P E O P L E T O F I N D A C U R E

VALVANO HONORED FOR WORK TO FIGHT CANCER

Chuck Perou, PhD, and Nicholas Valvano

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VS. CANCER FUNDS PEDIATRIC CANCER RESEARCH

2 0 1 5 – 2 0 1 6 D O N O R H O N O R R O L L !"

Chase Jones was afreshman at UNC-Chapel Hill when hewas diagnosed withstage IV brain cancer.

After being successfully treated atUNC Lineberger, he started his ownnon-profit organization called the Vs.Cancer Foundation with the goal offundraising for pediatric cancerresearch and supporting the needs ofpatients and families duringtreatment. Since 2013, Vs. Cancer hasgenerously granted UNC Linebergermore than $245,000, including themost recent gift of $115,000 tosupport UNC pediatric cellularimmunotherapy trials and research,and specifically, the work of BarbaraSavoldo, MD, PhD.

Chase, tell us why you’veexpanded the scope of Vs. Cancerresearch funding to includepediatric immunotherapy.It’s very rewarding to me to be ableto give back through Vs. Cancer tothe cancer center that saved my life.Knowing that UNC Lineberger,where I was treated, is a publichospital and serves everyone,regardless of their ability to pay, isreally amazing, because it’s one of

the best research facilities in theworld. Immunotherapy is apromising tool that will provide hopeto many pediatric cancer patientswho have no other treatment options,and as a cancer survivor, it’shumbling to play a role in Dr.Savoldo’s research to help these kids.

Dr. Savoldo, what does it mean tobe able to o#er immunotherapytreatment here in NorthCarolina?Patients can be treated closer to theirhome, which lightens the load for theentire family, both financially andemotionally. It is always a strugglefor parents to stay with their sickchild during therapies while they tryto continue working to financiallysupport the needs of the othermembers of the family; having totravel to another state for treatmentonly compounds that problem.Treatment at UNC also makes lifeeasier during a very di!cultdiagnosis, enabling loved ones toprovide the emotional supportsystem that is particularly critical forthe family, including hospital visits,home-cooked meals, housekeeping,childcare and transportation forsiblings.

Chase, in addition to thisresearch gift, you’ve also made avery generous donation throughVs. Cancer to replace/repairitems in the N.C. Cancer HospitalPediatric Oncology andHematology Clinic.Our whole goal for Vs. Cancer is tofund local research and to help kidshave the best experience possible inthe Peds Oncology Clinic. Part of ourgift will be used for up-fitting thetechnology that operates interactivegames in the clinic waiting room.We’re also repairing the clinic’s kid-sized racecar so children cancontinue to play, have fun and, asmuch as possible, enjoy their visit tothe N.C. Cancer Hospital. To thinkthat we can help provide a positiveenvironment for children who aregoing through this disease isextremely rewarding.

Dr. Savoldo, what kind of impactdo donors like Chase Jones andVs. Cancer have on yourresearch?Although we have made greatprogress in treating certain pediatriccancers like leukemia, there is stillmuch work to do in our fight againstresistant solid tumors in children.However, childhood cancer researchis vastly underfunded, which is atragedy, as these children have theirentire lives ahead of them. As aresearcher, I see this not only as achallenge, but also, as an opportunityto help save lives. Philanthropicsupport from donors like ChaseJones and Vs. Cancer will help intranslating our continuous labdiscoveries and studies into theclinic as cures for children.

Vs. Cancer team From L to R: Brant Masters, Ti"any Drummond Armstrong,Kathleen Kenney, Chase Jones (founder), Ashleigh Kincaid, and Eric Stahl.

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Venture tscientific

S E C T I O N T W O

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to seek solutions

Nirali Patel, MD

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V E N T U R E T O S E E K S C I E N T I F I C S O L U T I O N S

David Routh, Vice Chancellorfor University Development,presents Ken and CherylWilliams with an Elaine O’Neilcustom design during thededication of The TonyWilliams Lobby.

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KEN AND CHERYL WILLIAMS MAKE !"# MILLION GIFT TO ADVANCE CANCER RESEARCH

2 0 1 5 – 2 0 1 6 D O N O R H O N O R R O L L !"

Ken and CherylWilliams wereoverwhelmed withgratitude whendozens of their

colleagues, friends and familymembers gathered on Thursday,January 21, 2016, to celebrate thenaming of the N.C. Cancer Hospitallobby in memory of the couple’sbeloved son, Tony Williams. Theoccasion was bittersweet, as Ken andCheryl’s son passed away just fouryears ago, but it was also thecelebration of a transformational $10million gift the couple believes willprovide hope to families facingpotential heartache.

“When you look backon your life, you haveto ask yourself, ‘HaveI done what I can tohelp others? Is thisworld a better placebecause I was here?’Those are bigquestions, but canceris a big disease.”

– Cheryl Williams

“The pain of losing Tony is a sorrowthat will always be a part of our lives,”Ken says. “Cheryl and I hope thatthrough our gift to UNC Lineberger,and because of the life-saving cancerresearch it will fund, eventually, otherfamilies won’t have to experience thesu!ering that accompanies the lossof a loved one.”

Through the Ken and CherylWilliams Fund for Venture Initiativesat UNC Lineberger, the couple choseto make the extraordinary gift of $10million to fund cancer researchinitiatives that hold the greatestpromise for cures. The gift isunrestricted, giving leaders of thecancer center the greatest flexibilityto earmark the funds for emergingresearch opportunities that can makethe greatest impact against cancer.

“I spent my professional career inpharmaceutical research,” explainsKen, who retired as a senior vicepresident from Quintiles, the world’slargest provider of commercialoutsourcing services andbiopharmaceutical development. “So I’ve always been interested innew, cutting edge treatments andtherapies. That’s one of the thingsUNC Lineberger is known for –being a world-class leader in cancerresearch – so Cheryl and I were veryinterested in finding a way we couldsupport the cancer center’s mission.Also, we both have personallysu!ered loss due to cancer, so we’repassionate about the quest for cures.We have faith that researchers willeventually unlock the mysteriesbehind cancer, and there’s no reasonthose discoveries can’t be made righthere in Chapel Hill, North Carolina.”

Williams gift supports $200 million goalKen and Cheryl’s generous giftplayed a pivotal role in UNCLineberger fundraising successduring the 2016 fiscal year, whichtotaled a record $16.2 million in

philanthropic gifts and newcommitments. The cancer centeralso secured $12.9 million in grantsfrom corporations and private, non-governmental foundations. Thisbrought the total funds raised fromprivate sources to more than $29million for a second year.

“Every day, our care providers andscientists commit themselves to thepursuit of today’s best care andtomorrow’s best hope,” says MartinBaucom, senior executive director,UNC Lineberger Development andCommunications. “Ken and Cheryl’sgift demonstrates a similar level ofcommitment to fighting cancer.They’ve set a lofty leadershipstandard for what philanthropy cando to advance the life-saving missionof UNC Lineberger, and their senseof timing couldn’t be better. We areviewed nationally as a cancer centeron the move, and we are also in theearly stages of an eight-yearfundraising campaign. Ken andCheryl’s philanthropy harnesses ourtremendous momentum and willinspire additional investmentsthroughout the campaign. That’swhat leadership is all about.”

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Janet Mazzureo

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V E N T U R E T O S E E K S C I E N T I F I C S O L U T I O N S

For decades, scientistshave been trying tofigure out how to use thebody’s own immunesystem to fight o!

cancer. After all, our immunesystems can fight o! all kinds ofother health threats, so why not thisdisease? But nothing seemed toreally work – that is, until the 1990s,when researchers began expandingthe use of a treatment calledimmunotherapy that resulted inslowed tumor growth and longerpatient survival rates.

An important part of the immunesystem is its ability to tell thedi!erence between normal cells inthe body and those it sees as“foreign.” This lets the immunesystem attack the foreign cells whileleaving the normal cells alone.

However, scientists recentlydiscovered that cancer has the abilityto put on what some call an“invisibility cloak.” Simply put,cancer can disguise itself andprevent the immune system’s attack,which keeps the patient’s body fromhealing. Fortunately, thanks to abreakthrough in therapies calledcheckpoint inhibitors, scientists havefound a way around one part of theinvisibility cloak.

Checkpoint inhibitors are drugs thatturn o! the invisibility cloak so somecancers can’t hide from the immunesystem. Researchers are thrilled thatthese drugs seem to be working forup to one quarter of patients withadvanced cancer — melting away thetoughest tumors, such as somemelanomas, which are the deadliestkind of skin cancer.

Janet Mazzurco: “Dr. Collichionever gave up hope.”Janet Mazzurco’s seven-year battlewith melanoma began with a simplebiopsy at her dermatologist’s o"cein December 2009. What shethought was a small spot on her rightarm – just the size of a pencil eraser –turned out to be an extremely deepmelanoma that required surgeryunder general anesthesia. “Mysurgeon had to cut through muscleto get the cancer, removing threelymph nodes in the process,” saysJanet. “Those lymph nodes werenegative, but I decided to come toUNC Lineberger for a secondopinion.”

IMMUNOTHERAPY: BREAKING BARRIERS, BEATING CANCER

“I’ve learned to liveevery day as if it’s the last day.”

– Janet Mazzurco

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When UNC oncologist FranCollichio, MD, did a PET scan onJanet, the results showed no visiblesigns of cancer, so Janet returnedhome to Greensboro, believing herbout with melanoma was over. Buton July 4, 2014, she awoke with asplitting headache. “I went to ourlocal emergency room the followingday, where they performed a CTscan,” Janet explains. “They told me Ihad a large tumor on the back of mycerebellum. I was terrified.”

“Studies are beingdone on thecombinations ofthese checkpointinhibitor drugs sothat in the future,doctors candetermine the bestcourse of treatmentfor each specificpatient.”

– Fran Collichio, MD

A month later, neurosurgeon HenryElsner, MD, removed the mass onJanet’s brain, and pathology reportsconfirmed Janet had stage IVmetastatic melanoma. Within weeks,she underwent stereotactic radiationsurgery, a targeted form of radiationto obliterate a small remaininglesion without subjecting her entirebrain to unnecessary treatment.Unfortunately, subsequent scansshowed the lesion had doubled insize, and in December 2014, hersurgeon operated again. “Still, thecancer grew, and I was getting

sicker,” Janet says. “There wasnothing else my Greensboro medicalteam could do, so I came back to seeDr. Collichio. She ran more tests andfound the cancer had spread to myliver and lungs.”

As luck would have it, a checkpointinhibitor drug called Ipilimumab

(known commercially as Yervoy) hadjust come out of clinical trials andwas approved by the Food and DrugAdministration (FDA). Collichioimmediately prescribed a series offour treatments – each four weeksapart – that began in January 2015.By May, Janet’s tumors begandisappearing.

“I was very pleased with Janet’sprogress,” says Collichio, a UNCLineberger member and clinicalprofessor of Hematology andOncology at UNC – Chapel Hill.

“After four months, her scans showedobvious disease regression, and byMarch 2016, there were no visibletumors. Her LDH levels, which aremarkers we use to evaluate apatient’s response to treatment, fellinto the normal range. I was thrilledto give Janet the news: she was inremission.”

However, Janet’s recovery wasn’twithout its struggles. After her lasttreatment, she was plagued by colitis,which is a known side e!ect ofIpilimumab. “I was hospitalized fourtimes because I was so sick, but,thankfully, steroid treatments weree!ective. And other than having a bitof fatigue, I’ve done really well.”

Janet is slowly but surely returningto the things she loves to do. She andher husband Tony own a marble andtile company as well as a homerenovation and constructionbusiness. Public service is also highon Janet’s list of priorities. She wasjust reappointed to a three-year termon the Greensboro ZoningCommission, and she proudly serveson UNC’s CCNE board as a patientadvocate, sharing her first-handexperiences as a metastaticmelanoma survivor.

“I’m a survivor because of my faith inGod, and I also have great faith in Dr.Collichio,” says the 56-year-old. “Sheis absolutely amazing – an attentive,compassionate, brilliant doctor. Butthere’s no ego. She’s always treatedme as an equal, and she respects mythoughts and opinions. Mostimportantly, Dr. Collichio never gaveup hope, and as someone who knowswhat it’s like to face cancer, that’s all Icould ask for.”

Fran Collichio, MD

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V E N T U R E T O S E E K S C I E N T I F I C S O L U T I O N S

According to theNational CancerInstitute, inheritedgenetic mutationsplay a major role in

about five to 10 percent of allcancers. At UNC Lineberger, ourCancer Genetics Program providesconsultations and risk assessmentsfor people who have a strong,inherited predisposition to havingcancer.

The following patient profile featuresBeth Silverstein, a remarkable youngwoman who was told that, because ofher genetic profile and familyhistory, she had an 80 percent risk ofgetting breast cancer and a 50percent risk of getting ovariancancer. Beth’s parents, John andLeslie Silverstein, serve on UNCLineberger’s Board of Visitors.

Silverstein finds health, hope andfreedom at UNC LinebergerWhen Beth Silverstein looks into themirror, it’s easy to see herresemblance to her mother, LeslieSilverstein. However, while thesimilarities in their outwardappearances are obvious, Beth didn’tknow if she had inherited hermother’s genetic history thatpredisposed her to cancer.

“We are of Ashkenazi Jewish decent,an ethnicity with a much higher riskof certain gene mutations thatfrequently lead to breast and ovariancancer,” explains Beth. “Mygrandmother died at age 36 of breastcancer, and my mother wasdiagnosed with the same disease atage 39. My mom went through

genetic testing because so many ofour family members had battledvarious kinds of cancers, and sheencouraged me and my sister Amyto be tested as well.”

When Beth’s genetic results cameback, she learned she had testedpositive for the BRCA1 genemutation, the same mutation hermother and grandmother had. Shewas heartbroken.

Next Steps and ChoicesIn April 2008, Beth came to UNC tomeet with James P. Evans, MD, PhD,a UNC Lineberger member andBryson Distinguished Professor ofGenetics and Medicine, along withCatherine Fine, MS, CGC, a geneticcounselor. “We reviewed Beth’sgenetic results and mapped out herfamily history, and we determinedthat her risk for developing breast

CANCER: IT’S ALL IN THE GENES

Beth Silverstein

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cancer was in the upper 80th percentile,” explains Evans. “Catherine and Idiscussed her options with her, which included having a bilateralmastectomy, or she could choose enhanced surveillance consisting ofregular visits to our high-risk breast cancer clinic for periodic breast exams,mammograms and MRI’s.”

But that wasn’t the only di!cult decision Beth would have to make. Due toher genetic history, Beth had a 50 percent chance of developing ovariancancer. During their counseling session, Evans explained to Beth that asshe aged, her risk would substantially increase. “As a geneticist, I becomevery nervous when patients like Beth reach their mid-40s and have nottaken preventive measures,” says Evans. “Unfortunately, there are no goodmodalities for detecting early-stage ovarian cancer; the symptoms arevague at best and often mimic other health issues. Once a woman has thedisease, it can be extremely di!cult to treat.”

Beth was overwhelmed by the news but decided to approach the situationwith a positive attitude. To protect her fertility, she chose to go through eggretrieval and then to have the eggs frozen for later fertilization andimplantation. Then in 2014, Beth met with oncologist Carey Anders, MD,and surgical oncologist, David Ollila, MD. After an extensive review ofBeth’s case, Ollila recommended she have a bilateral mastectomy. Whilethe recommendation may seem aggressive to some, Ollila says theopposite is true in BRAC gene mutation carriers.

“Surveillance is not the same as prevention. Obtaining annual breastimaging only serves to try to detect the cancer early. It doesn’t prevent thecancer from forming. If Beth had chosen to forgo surgery and decidedinstead to take a wait-and-see attitude, it’s very likely that at some point inthe near future, we would be discussing a cancer diagnosis, followed bysurgery, radiation and chemotherapy. And that’s IF we caught it earlyenough. Beth didn’t make this decision lightly; it was a thoughtful, rationalchoice, and a wise one, in my professional opinion, supported by concretegenetic evidence.”

On February 3, 2015, Ollila performed Beth’s bilateral mastectomy, andBeth’s reconstruction surgery was completed in the summer of that sameyear. She also met with Evans and Fine again, this time to review her labwork and to further discuss the surgical removal of her ovaries.

In February 2016, Beth had a salpingo-oophorectomy, which is the removalof the fallopian tubes (salpingectomy) and ovaries (oophorectomy). Thetwo-and-a-half hour surgery went well, but it immediately sent Beth intomenopause. She’s now dealing with the after-e"ects that include hot flashes,insomnia and “foggy brain.” But for Beth, this is the new normal. While thesurgeries have changed her, both physically and emotionally, she feelsempowered as she enters the next decade of her life.

“Some people ask me why I decided to take, what they perceive to be, suchradical steps. I won’t lie, it was hard,” she says. “But the moral of this story isthat you need to know your family history, and recognize that geneticsa"ect every generation. I’m not a victim; I took control of my health,making the choices that were right for me. Now I get to live my life withoutfear of what’s going to happen. That’s liberating.”

SILVERSTEINS HONOREVANS WITH GIFT TOLINEBERGER John and Leslie Silverstein wereintroduced to UNC Lineberger in 1988,the same year Leslie was treated for stage I breast cancer. “We attended aLineberger fundraising event, where weheard (former UNC Lineberger director)Shelley Earp, MD, talk about thegroundbreaking research taking place atthe cancer center,” says Leslie. “We werefascinated, and we joined the Board ofVisitors soon after, serving on variouscommittees.”

Then, in 1990, Leslie was diagnosed withstage IV lung cancer. Her lung wasremoved, and since there was noevidence of any more disease, she wastreated with Tamoxifen. She remainscancer-free. Meanwhile, cancer struck theSilverstein family again in 2015, whenJohn was treated for prostate cancer.

“We have experienced cancer in verypersonal ways, and, of course, ourdaughter Beth has gone through a seriesof surgeries to protect herself against thedisease,” Leslie explains. “John and I arevery grateful for the care our family hasreceived at the N.C. Cancer Hospital, andwe wanted to make a gift to express ourappreciation. When we considered theincredible work Dr. Jim Evans is doingwith genetics and how it has directlya"ected our family, we chose to make anaming gift in his honor. UNCLineberger is fortunate to have him ontheir team.”

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V E N T U R E T O S E E K S C I E N T I F I C S O L U T I O N S

Partnerships – both local and global – play a key role in UNCLineberger’s success as a comprehensive cancer

center. We frequently collaboratewith individuals or organizationsto achieve goals that may otherwisebe unattainable if pursuedindependently. The ultimate purposeof our partnerships is to seekscientific solutions that provide thebest possible cancer care to ourpatients.

Within the last year, our partnershipwith IBM/Watson has beenextremely productive and showsgreat promise for the future use ofartificial intelligence at UNCLineberger. Watson is a technologyplatform that uses natural languageprocessing skills to understandgrammar and content, process largeamounts of “big data,” and then,based on evidence and the quality ofthe information it’s given, it’s able topresent answers and solutions toquestions or problems. You mayremember Watson as the computerthat played on the game show“Jeopardy!” a few years ago.

Hal McAdams: Back on thegreens, back to life Hal McAdams loves to play golf, andif the weather is good, most days

you’ll find him at the GreensboroCountry Club, decked out in hisfinest haberdashery. He’s a fixture onthe course, having served on theclub’s board of directors for years.But in 2014, Hal put away his golfclubs and made his way to UNCLineberger for a second opinion afterbeing diagnosed with advancedbladder cancer.

“I wasn’t feeling well, and afterrunning some tests, my familypractitioner referred me to a localurologist,” explains the 75-year-oldretired furniture merchandiser. “Theurologist found a tumor andremoved it, but he was unable to getall the cancer. I came to UNC todiscuss my treatment options.”

Hal met with Billy Kim, MD, whosoon began treating his stage IIIbladder cancer with a standard ofcare chemotherapy. But Hal’s cancerprogressed, and the medicine causedhim to become very ill. After moretesting, Kim recommended surgeryto remove Hal’s bladder.

“Following the procedure, I sent abiopsy of Hal’s tumor to besequenced – or de-coded – throughUNCseq, comparing it to normaltissue samples,” says Kim. “Thatanalysis told me that Hal would verylikely respond well to a drug calledEverolimus (commercially known as

A!nitor), which is FDA approved forother cancers, but not for bladdercancer. Hal agreed to try it, and hehad a wonderful response. Heimmediately started feeling better,and subsequent scans showed areduction in the cancer that wasoriginally in his lymph nodes. But tobe honest, we didn’t know why.”

In December 2015, IBM’s Watsongave Kim his answer. “I took thesequencing data from Hal’s tumorbiopsy and ran it though the Watsontechnology. Within 24 hours, Watsonwas able to provide a scientificexplanation as to why Hal wasconsidered an “exceptionalresponder.” That’s the value ofWatson,” Kim says. “It’s can quicklyextract key information from a hugeamount of scientific data and revealinsights, patterns, and explanationsthat we might not have discoveredon our own.”

These days, Hal is back on the golfcourse, and he is extremely gratefulfor the care he continues to receive atUNC Lineberger. “You know, it’s sortof ironic,” the UNC alum (’65) says.“When I was an undergrad atCarolina, I shared a house with oneof the Lineberger boys. Now I’mbeing treated at the cancer centerthat is his family’s namesake, and Iwouldn’t want to be anywhere else.”

ARTIFICIAL INTELLIGENCE:A tool for solving questions about cancer

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McAdams has chosen to invest in Dr. Billy Kim’sbladder cancer research. “It’s one of the mostexpensive cancers to treat, yet research is woefullyunderfunded,” says a grateful Kim.

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Build clinicalresearc

to advanc

S E C T I O N T H R E E

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al excellence: ch and care ce hope

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Amy Charney

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B U I L D C L I N I C A L E X C E L L E N C E : R E S E A R C H A N D C A R E T O A D VA N C E H O P E

Clinical trials are animportant step indiscovering newtreatments for breastcancer and other

diseases, as well as new ways todetect, diagnose, and reduce the riskof disease. While clinical trialsprovide evidence of what does anddoesn’t work for patients, trials alsohelp researchers and doctors decideif the side e!ects of a new treatmentare acceptable when weighed againstthe benefits. On average, a newmedicine to treat breast cancer hasbeen studied for at least six years -and sometimes, many more - beforea clinical trial testing the e"cacy ofthe medicine begins.

Who says you can’t go home?Amy Charney, a wife, mom and avidrunner, had already registered to runthe 2015 Boston Marathon when shewas told she had breast cancer. Buther diagnosis didn’t stop her fromreaching the finish line.

Amy’s diagnosis came as a completesurprise back in November 2014,when her family was getting ready tocelebrate her daughter’s Bat Mitzvah.

“We’d gone shopping for partydresses, and I was trying on somethings in the fitting room,” says Amy.“And that’s when I saw it: a small,pea-sized lump on my breast. I madean appointment with my doctor, andsince it was almost time for my

CLINICAL TRIALS LEAD TO NEW TREATMENTS

Lisa Carey, MD

“I wanted to be Amy,the marathon runner,not Amy, the womanwith cancer.”

– Amy Charney

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annual visit, she suggested I have adiagnostic mammogram. That’swhen I came to the N.C. CancerHospital.”

Amy’s mammogram results werenegative, but because she has densebreasts, her breast radiologistrecommended an ultrasound, whichled to a biopsy. Amy was diagnosedwith ductal carcinoma in situ, orDCIS, the most common type of non-invasive breast cancer. Afterevaluating her options, Amy chose tohave a lumpectomy and radiation.However, her case was sent to theradiology review board. Due to thedensity of her breasts, they wantedmore information and asked Amy tohave an MRI.

Those results showed even moreDCIS in the tissue, and after anotherbiopsy, the board strongly suggestedthat Amy have a mastectomy. OnJanuary 13, 2015, David Ollila, MD,surgical director of the UNC BreastCenter, performed a partialmastectomy and sentinel nodebiopsy. Fortunately, Amy’s lymphnodes were clear, but she did have a six millimeter stage I invasivebreast cancer called “HER2-positive.”Her oncologist, Lisa Carey, MD, theRichardson and Marilyn JacobsPreyer Distinguished Professor inBreast Cancer Research,recommended chemotherapy forAmy.

“Years ago, this was worst, mostaggressive type of cancer,” explainsCarey. “But then studies began toshow that the anti-HER2 drugHerceptin, combined withchemotherapy, really changed thegame and made it a much moretreatable cancer. But questionsremain about the best way toadminister these treatments.”

Carey explains that normally,patients are given high doses ofseveral chemotherapy drugs withHerceptin added, followed bycompletion of a year of Herceptin.

However, while this treatmentprotocol is very e!ective, the sidee!ects can be tough on the patient.“So when Amy and I talked about hertreatment options, I told her about aclinical trial initiated by colleaguesat Dana-Farber Cancer Institute.UNC is part of a group of academicinstitutions that work together ontrials like this one,” says Carey. “Inthis study, we’re using a new drugcalled trastuzumab emtansine,known commercially as Kadcyla,which is a chemotherapy drugattached to Herceptin, so thechemotherapy only goes into thecancer instead of all over the body.The combination is called TDM1, butits nickname is the ‘Trojan Horse’

because it’s such a targeted form oftreatment. I was pleased that Amyagreed to be a clinical trialparticipant.”

O# and RunningAmy began taking TDM1, but still,she kept on running with herdoctor’s permission. Then on April20, 2015, just six days after achemotherapy treatment, Amy stoodat the starting line of her seventhBoston Marathon while her husbandJonathan and daughters Julia,Elisabeth and Ava cheered her on. “Ikept thinking, ‘You can’t finish if youdon’t start.’ I just wanted to cross thefinish line, not necessarily beat myown time. And before I knew it, wewere o! and running.”

The Boston Marathon is a gruelingrace with a course that windsthrough eight Massachusetts citiesand towns. One of those is Brookline,the place where Amy grew up andwhere her mother, who died of lungcancer, was laid to rest. “Miles 22through 24 of the Marathon runthrough my hometown,” explainsAmy. “It was a pretty emotionalmoment for a number of reasons.”

Amy crossed the finish line feelingexhausted, relieved, and mostimportantly, like a champion. “Byrunning the Boston Marathon, Ilearned that, in spite of breast cancer,I am still me,” she says. Meanwhile,Carey says she’s happy with Amy’sresponse to the clinical trial drug andlooks forward to seeing the finalresults of the study. “We’re findingthat it’s as important to tailor apatient’s course of care to lesstreatment if possible, as it is to tailorcare to more treatment if necessary,”says Carey. “It’s good to haveoptions.”

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Matt Ewend, MD

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B U I L D C L I N I C A L E X C E L L E N C E : R E S E A R C H A N D C A R E T O A D VA N C E H O P E

Astem cell isessentially a “blank”cell, capable ofbecoming another,di!erent type of cell

anywhere in the human body.Microscopic in size, stem cells arebig news in medical and sciencecircles because they can be used toreplace or even heal damaged tissuesand cells in the body, a sort of built-in repair system for humans.

In a first for medical science, UNCLineberger researchers are turningskin cells into cancer-hunting stemcells that destroy brain tumorsknown as glioblastoma – a discoverythat can o!er, for the first time inmore than 30 years, a new and moree!ective treatment for the disease.

Glioblastoma is a fast-growing,aggressive form of brain cancer. Thesurvival rate beyond two years for apatient with a glioblastoma is only30 percent because it is so di"cult totreat. Even if a surgeon removesmost of the tumor, it’s nearlyimpossible to get the invasive,cancerous tendrils that spreaddeeper into the brain, and inevitably,the remnants grow back. Mostpatients die within a year and a halfof their diagnosis.

“Current strategy to treat the diseaseis surgical removal of the tumor,followed by radiation andchemotherapy in hopes of killingremaining cancer cells. All of thosetreatments help, but it’s a verydi"cult disease, and patients

desperately need a better standard of care,” says Matt Ewend, MD, aUNC Lineberger member, Van L. Weatherspoon, Jr. EminentDistinguished Professor and chair of the Department of Neurosurgeryat UNC.

SKIN CELLS: CANCER!FIGHTING WARRIORS

Long-term survivors ofglioblastoma are rare.We hope to change that.

– Matt Ewend, MD

Induced neuralstem cells (shownin green)engineered fromskin cells andarmed to killcancer are shownas they attackglioblastoma cells(pink) that areinvading the brain.

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Researchers want to improve thosestatistics by developing a newpersonalized treatment forglioblastoma that starts with apatient’s own skin cells, with the goalof getting rid of the canceroustendrils, e!ectively killing theglioblastoma.

Shawn Hingtgen, PhD, a UNCLineberger member and an assistantprofessor of molecularpharmaceutics in the UNCEshelman School of Pharmacy, sayshis team has engineered these stemcells so that they can actually huntdown the cancerous tumor cells.

“This requires a conversion processcalled ‘direct reprogramming’,”explains Hingtgen. “We turn skincells known as fibroblasts intospecial neural stem cells. Workingwith mice, our team has shown that

these so-called ‘induced neural stemcells’ have an innate ability to movethroughout the brain and home in onany remaining cancer cells. The teamalso showed that these stem cellscould be engineered to produce atumor-killing protein, creating apromising new strategy for killingglioblastoma cells embeddedthroughout the normal brain.”

In mouse studies, survival ratesdoubled and tripled. The hope is thenew method would do the same inhuman patients.

“In a test dish with pink humantumor cells, scientists can see thegreen stem cells hunting down thetumor cells,” says Ewend. “Thosecells can see things that I can’t see asa surgeon. They can find cells I can’tfind and o!er us a chance to get ridof those last few remaining cells that

cause the recurrences.”

Researchers are already collectingbiopsies from glioblastoma patientsto test the concept on human tissue.They hope it will result in humantrials and an e!ective therapy to addto current treatments. If ultimatelysuccessful in human trials, UNCresearchers envision the conceptbeing adapted to fight other types ofbrain cancer, including pediatriccases and “breast-to-brain-cancer” inwomen.

“Our work represents the newestevolution of the stem-cell technologythat won the Nobel Prize in 2012. It’sthe first time this directreprogramming technology hasbeen used to treat cancer, and wehave high hopes for success,”Hingtgen says.

Shawn Hingtgen, PhD

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B U I L D C L I N I C A L E X C E L L E N C E : R E S E A R C H A N D C A R E T O A D VA N C E H O P E

One-in-two men andone-in-three womenwill face cancer intheir lifetimes. AtUNC Lineberger, we

are diligently working to changethese statistics – not just for thepatients who are currently battlingcancer, but for all those who will bediagnosed with cancer in the future.However, we can’t do it alone. Yourfinancial support is critical to our

next-generation cancer research andexceptional patient-centered care. Soit’s with heart-felt thanks that weshare the success of our first-everannual matching gift opportunity, acampaign that truly shows the powerof the collective good.

In March 2016, an anonymouscouple made a gift to UNCLineberger, but there was a catch –the amount would be based on the

generosity of others. “This cancercenter is making a significant,positive impact on the lives of NorthCarolinians, and it’s time for peopleto step forward and show theirsupport,” the donors said. “Therefore,we will match every gift, dollar fordollar, up to $50,000. We hope ourfriends and neighbors will rise to the challenge.”

And did they ever! Within two weeksof the initial gift challenge, thecancer center received $50,000 inmatching gifts. But it didn’t stopthere. After hearing about thecampaign’s success, UNCLineberger Board of Visitorsmembers Bill and Nancy Grahamwere inspired to issue an additional$50,000 challenge, e!ectivelyquadrupling the gift! As of thisnewsletter print date:• UNC Lineberger had received

795 gifts, totaling $253,828.• 86 donors made their first-ever

gift to the cancer center.• Many contributors increased their

fiscal year giving by making aspecial gift to the match.

• This matching challenge resultedin the largest number of donationsto UNC Lineberger for any onlinefundraising e!ort of its kind.

“This campaign accomplished two major goals,” explains BetsyGentry-Bumm, director of annualgiving. “It increased awareness aboutUNC Lineberger, North Carolina’sonly public NCI comprehensivecancer center. It also raised anextraordinary amount of money forcancer research, something we willfeel the e!ects from for years. Forthese reasons, we are truly humbledby everyone who supported thismatching challenge.”

DONORS’ MATCHING GIFT CHALLENGERAISES MORE THAN !"#$,$$$

Bill and Nancy Graham

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BILL AND NANCYGRAHAMThere’s power in a matchLike many UNC Lineberger supporters,Bill and Nancy Graham were drawn to ourcancer center for dual reasons – bothfamilial and medical. Bill’s uncle, PageGraham, was one of the original membersof the UNC Lineberger Board of Visitorsand was extremely proud of the cutting-edge research being done here to help hisfellow North Carolinians. Page recruitedBill and Nancy to serve on the board, andthrough the years, the two have becomeavid cheerleaders for the cancer center.They have also been personally a!ectedby cancer and have a keen understandingof UNC Lineberger from a patient’sperspective.

“In 2007, I was diagnosed with breastcancer and began treatment here inWinston-Salem, but our daughterencouraged me to get a second opinion atLineberger. I’m so glad I did,” says Nancy.“When I walked in the door at UNC, Iknew I was in the right place. Dr. LisaCarey was my oncologist and providedsuperlative care. The late Dr. Keith Amoswas my surgeon, and I adored him. I feellike I hit the jackpot with regards to myphysicians. I had chemo in Chapel Hilland came back home to Baptist Hospitalfor my radiation. Today, I’m thankful to becancer-free.”

When asked what appealed to the coupleabout the ‘matching’ nature of this givingopportunity, Nancy says it’s all aboutdoubling the power of the gift. “Bill and Iknew time was of the essence if we wantedour contribution to have the most impact,and we are so pleased that others rose tothe challenge, matching the fundingdollar-for-dollar,” says Nancy. “Lookingback at the campaign’s success, we’ve seenthe collective abilities of gifts, whetherlarge or small, to help patients like TrentHandley have a fighting chance to beatcancer.”

HANDLEY TWINS FEATURED IN LINEBERGER CAMPAIGNIn March of 2015, Trent Handley was diagnosed with a rare form of cancercalled “natural killer cell leukemia.” Worldwide, there are only about 60known cases of this kind of cancer. Trent was admitted to the N.C. CancerHospital; his fraternal twin brother Tyuss was devastated.

Pediatric oncologist Brent Weston, MD, and a team of caregivers workedfeverishly to get him the right protocol and treatment while the familyspent months in the cancer hospital. And then the good news came: Trentwas in remission.

“As a mom, when you watch your child going through something that’slife-threatening, and then to see that miracle…there are no words toexpress our gratitude,” says the twins’ mother, Tanisha Handley.

As part of the matching gift challenge, we featured Trent and Tyuss in ouronline campaign video. To learn more, go towww.unclineberger.org/twins.

Trent and Tyuss Handley

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B U I L D C L I N I C A L E X C E L L E N C E : R E S E A R C H A N D C A R E T O A D VA N C E H O P E

Understanding whatcauses cancer, whogets it, and why, is animportant area ofresearch at UNC

Lineberger. We are frequently asked,“How close are you to preventingand curing breast cancer?” The goodnews is, breast cancer mortality ratesare declining, and according toChuck Perou, PhD, we can expectthat progress to continue.

“We now know that breast cancer isnot one single disease, but at leastfive,” says the May Goldman ShawDistinguished Professor of MolecularOncology at UNC. “Using genomics,genetics, and laboratory models, mycolleagues and I are focused on

identifying the genetic mutationsthat cause these aggressive types ofbreast cancer. Based on that data, wework to develop novel therapeuticstrategies that specifically targeteach of these distinct subtypes.”

While funding for Perou’s researchcomes from many sources,philanthropic support from localdonors like the late Minhthu Nguyenand her husband Padrick Barrettmake future scientific breakthroughspossible.

Minhthu Nguyen: theultimate giverWhen 34-year-old Minhthu Nguyen,DDS, was diagnosed with stage IVbreast cancer, she and her husbandPadrick Barrett were stunned andshaken by the news. “We were brandnew parents of a baby girl, Lien, so tolearn about the severity of Minhthu’sillness was pretty shocking,” saysPadrick. “But in typical fashion,Minhthu didn’t wallow in self-pity.

CANCER RESEARCH: MORE THAN JUST TREATMENT AND DETECTION

Padrick Barrett with daughter Lien

ChuckPerou, PhD

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She told me she wanted to approachher treatment with grace and dignity,and that’s what she did.”

Minhthu and Padrick sought carefrom Mark Graham, MD, of WaverlyHematology Oncology in Cary, NC,where he told the couple it waspossible that Minhthu’s pregnancyhad actually masked the symptomsof her disease and allowed her tumorto progress undetected, since thesigns and symptoms of breast cancercan be similar to the changes in awoman’s body during pregnancy.”Minhthu had advanced metastaticcancer, and I strongly encouragedthem to pursue treatment at UNCLineberger, which is guided by someof the exceptional findings from theChuck Perou lab,” says Graham. “Itold them that Chuck is NorthCarolina’s best kept secret, a true

forerunner in the field of breastcancer research and genomics.” Thetwo took Graham’s advice andworked closely with Perou and BenCalvo, MD, both UNC Linebergermembers, to fight her disease. In fact,they were so impressed with Perou’slab, his commitment to research, hishumility and exceptional caregivingspirit that they have contributedmore than $100,000 to his work.

“Minhthu, an eternaloptimist, wantedother patients to feelhopeful aboutbeating cancer.”

– Padrick Barrett

“The investment that Minhthu andPadrick have made to my work isboth substantial and inspiring,” says

Perou. “As a researcher, every dollarhelps, but more importantly, meetingindividuals like Minhthu gives us anadditional drive to try and make adi!erence in the lives of cancerpatients. This gives me more focusand more meaning to my work.”

Minhthu’s generosity spilled overinto her professional life as well. Ather dental practice, Gentle FamilyDentistry, she frequently performedpro bono services for other cancerpatients, and there were specific dayswhen a portion of o"ce receipts wentto charity. “Minhthu was committedto making life better for our sta! andpatients,” says Padrick. “She wasalways doing special things forothers. She was the ultimate giver.”

The gift that keeps givingMinhthu Nguyen passed away onSeptember 8, 2015, following hercourageous four-year battle againstbreast cancer. To honor Minhthu’smemory, her brother, Dr. PhongNguyen and her husband Padrickmade a gift of $250,000, choosing toname the mammography receptionarea in the N.C. Cancer Hospital forher. They also furnish the space withfresh flowers at all times and providerefreshments once a month forpatients.

“UNC Lineberger is a wonderfulleader in cancer research and care,but many people aren’t aware of theamazing work they do every day,”says Padrick. “Every person we’vemet here has been genuinelywelcoming, just like Minhthu was.She didn’t get to live the life shewanted, but by making this gift toUNC Lineberger, our family is doingwhat we can to keep her spirit alive.”

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Unite across to beat

S E C T I O N FO U R

population

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s cancer

n sciences

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Ethan Basch, MD, MSc,personifies what itmeans to be a clinician-scientist. In the clinic,Basch provides

compassionate, expert care forpeople who have urologic cancers,with a focus on prostate cancer.Outside the clinic, he is a nationalleader in the study of patient-reported outcomes, a field ofresearch that measures how cancertreatments a!ect patients’ overallwellbeing.

“Patient-reported outcomes – whichinvolves patients telling their healthcare provider how they’re feeling,how they are functioning, or asymptom they are experiencingduring treatment – provide criticalinsights that we clinicians typicallyhave not sought to capture in thepast,” explains Basch, who is thedirector of UNC Lineberger’s CancerOutcomes Research Program.

“While this is still a relatively youngfield of study, we are quickly finding

that this information has great value;it helps us to better assess the fullimpact of standard and experimentaltherapies on our patients,” Baschadds.

The Patient-Centered OutcomesResearch Institute recently awardedBasch a $5.45 million grant tosupport a national study toinvestigate whether integratingpatient-reported symptoms intocancer care management canimprove the patient’s quality of care

BASCH TO STUDY, MEASURE HOW CANCER PATIENTS’ FEEDBACK AFFECTS OUTCOMES

Ethan Basch, MD, MSc

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Jared Weiss, MD

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and quality of life, as well as measurethe impact of patient self-reportingon the healthcare delivery system.

“Patients with metastatic cancerfrequently experience symptomsthat cause distress, disability, andlead to urgent care visits,” saysBasch, a professor in the UNCSchool of Medicine Division ofHematology and Oncology. “Thesesymptoms often go unrecognizedand unaddressed by clinicians, eventhough there are many interventionsthat can provide relief.”

Making it easier for patients toreport their own symptomselectronically at regular intervalscould address this issue. Studies

have found that most patients arewilling and able to self-reportsymptoms during cancer care, andclinicians find this informationvaluable. This approach leads tobetter patient quality of life, reducesemergency room and hospital visits,and may lengthen survival.

Basch and his colleagues aim toinvestigate these findings on a largerscale. They have developed arandomized trial to betterunderstand the impact of patientsself-reporting symptoms. Their studywill track a number of outcomes,including physical function, qualityof life, survival, emergencyroom/hospital visits, andperspectives about relative benefits

and burdens from patients,clinicians, and nationalorganizations.

While technology has led to greatadvancements in cancer researchand care, developing simple tools toimprove patient-caregivercommunications may prove to behighly beneficial as well.

“Previous studies suggest that thebenefits of patient-reportedoutcomes will justify the personneland financial costs associated withthe program, but a randomized trialis needed to more clearly determinethe impact patient-reportedoutcomes has on quality of care andthe delivery of care,” says Basch.

Patients are able to share information about how they’re feeling on a regular basis, which helps physiciansbetter assess patient quality of life. The graphic above is an example of an online reporting tool.

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Being a teenager istough. Now, imaginebeing a teenager andhaving to deal with acancer diagnosis.

Adolescent and young adult (AYA)cancer patients are not only in astage of life where they’rediscovering who they are, gainingindependence from their parents andpreparing for adulthood; they’re alsohaving to deal with the pain, stressand confusion that accompanies alife-changing diagnosis.

Around the world, there is a growingappreciation of the unique needs ofteenagers and young adults whohave cancer. Unfortunately, there arestill huge gaps in terms of theirpersonalized psychosocial care. UNCLineberger has teamed up with theBe Loud! Sophie Foundation tochange that. The Be Loud! SophieFoundation is a local organizationestablished in memory of SophieSteiner. Diagnosed with germ-cellcancer at age 14, Sophie spentmonths undergoing treatment atUNC Lineberger. An energetic,sharp young woman, it did not take

long for Sophie to recognize that,while she was receiving the best careavailable, there was nothingspecifically designed for people herage. This absence of resources intailored care for adolescent andyoung adult patients — those ages 13to 26 — is something the NationalCancer Institute has referred to as a“no man’s land.”

In 2015, UNC Lineberger created aunique role at the N.C. CancerHospital to bridge this gap, aposition dedicated to designingsupport programs and providingresources to this demographic. TheAdolescent and Young Adultprogram began, and Lauren Lux, alicensed clinical social worker whounderstands the unique needs of thisspecific patient population, washired as director.

Lux says Sophie Steiner’s experienceof not quite fitting in is typicalamong many AYA patients in theUnited States. “It’s a tough groupbecause they’re not kids, and they’renot adults,” she says. “They don’tnecessarily feel at home in apediatric world, and they don’t reallyfeel at home in an adult world. Mymain objective is to help this patientpopulation maintain their identityand their dignity.” With a focus onpersonhood and humanness, Lux hasbegun to design programs thatsupport these patients in a way thatreminds them of what they loveabout life. “One of the goals we haveis that cancer will become a part ofthe patient’s narrative,” says Lux.“But it won’t become all of it.”

THE AYA PROGRAM Bridging the gap to ‘no man’s land’

Lauren Lux

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THE ADVOCATELauren Lux

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Two years after Sophie’sdeath, her parents, Lucyand Niklaus Steiner, andher sisters Elsa andAnnabel have fulfilled thefirst major goal of the Be

Loud, Sophie! Foundation they started in her honor:working with UNC Hospitals and UNC Lineberger to hirean AYA program director. But they are far from finished.Together with UNC, they now have the chance to supporta research-based program that advances the nationalunderstanding of how best to meet the unique needs ofpatients within the AYA demographic.

“When we started our foundation, we based ourgoalsetting on our own personal experiences withSophie,” explains Niklaus. “But we also realized that ourperspective was limited, because every child is di!erentand needs di!erent things. However, there is onecommon thread among this special patient population:they all want institutional understanding and support ofwho they are as individuals. These kids know who theywere before cancer, and they want to continue beingthemselves. That’s what Sophie wanted.”

Cancer is a unique diagnosis because a cancer patient’shealth can quickly change from one hour to the next.That’s especially hard on a young person who is seekingsteadiness as they are going through the maturingprocess towards adulthood. “It can be a blow to one’ssense of self, but we believe that UNC’s AYA Program willhelp lessen those feelings by enabling these teens andyoung adults to experience the milestones every youngperson goes through,” says Lucy. “And ideally, once theyare in remission, they can say, ‘I will face the rest of mylife with positive energy, because if I can get through

cancer, I can face anything. I will not live in fear, but withstrength.’”

The Steiners are extremely pleased that Lux is leading theAYA e!orts, saying she has a personality that is attractiveto teens and serves as an advocate for them. “We’veencouraged Lauren to identify program needs as theyevolve, and just since October 2015, she’s accomplished agreat deal,” Niklaus says. “She’s setting research goals,developing assessment tools to evaluate the program’se!ectiveness, and providing internal support to cliniciansas they learn more about caring for this age demographic.She’s terrific, and it’s a pleasure working with her.”

Melody Kessler slowlyturns her wedding bandon her left hand as she sits in an infusion chair atthe N.C. Cancer Hospital.Her husband, CalvinDeutschbein, hands her awater bottle and

encourages her to keep drinking. “You need to stayhydrated,” he says. The two are waiting for Melody’sregularly-scheduled chemotherapy treatment.

Melody and Calvin met in middle school in theirhometown of Loveland, Colorado, where they became fastfriends as members of the MathCounts team. Theirfriendship bloomed into romance, and they datedthroughout high school and college. The couple becameengaged, but their excitement was short-lived. OnDecember 30, 2014, Melody was diagnosed withHodgkin’s lymphoma.

THE DONORSThe Steiner Family

THE PATIENTMelody Kessler, 23Hodgkin’s lymphoma

The Steiner family

Melody Kessler

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“I had a lump in my neck behind my clavical andexperienced a continual rash and itchiness for about ayear, but I didn’t think it was cancer,” says Melody. “It wasa shock, to say the least.”

Melody was treated at University of Colorado Health,where she underwent six months of ABVD, the first linechemotherapy for Hodgkin’s lymphoma. On average,ABVD cures approximately 80 percent of patients whoreceive it. Melody’s treatment was successful, and aftergoing into remission, she and Calvin married on August8, 2015. They moved to Chapel Hill to attend graduateschool in August 2015.

Melody had been in remission about four months whenshe had a PET scan at UNC in October 2015. “My doctor,Steven Park, MD, said the results didn’t look good,”Melody explains. “He did a biopsy, which came backnegative, so he decided to do another PET scan inJanuary of this year. The cancer had come back.”

Another round of treatments began in March, this time, aform of chemotherapy called ICE that lasted 12 weeks.Her scans showed improvement, but she wasn’t inremission yet. “There was still some disease that waschemo-resistant,” says Melody. “So Dr. Park started me onanother treatment called GVD, which is used to treatpatients who have relapsed after remission fromHodgkin’s disease. I’m thrilled to say that after thatchemo, I am now cancer-free! I will have a stem celltransplant this fall.”

“When I met Lauren, she asked me about my experiencesas an AYA patient, and I told her it’s tough being this ageand having cancer. I want to be respected and heard,because my voice matters. I may be young, but I’ve donemore thinking about my mortality than most 60-year-olds.I really appreciate that UNC has a person like Laurenwho’s dedicated to helping me through my cancerjourney at this particular stage of my life. I know she’s inmy corner.”

To look at Ethan Johnson,you’d never know he’sbeen fighting a two-yearbattle with cancer. Hisblond, curly hair hasgrown back, and his paleskin now has a healthyglow, thanks to a bit ofsummer sun. His appetite

has returned, so he’s been eating lots of pasta lately.“Spaghetti’s my favorite,” he laughs. “I never get tired ofit.” He looks like an ordinary teenager.

But the last two years have been anything but ordinary forthe Johnson family. What started as an annual physical athis pediatrician’s o!ce turned into a nightmare onOctober 19, 2014, when Ethan was diagnosed withPhiladelphia Chromosome-Positive Acute LymphoblasticLeukemia (Ph+ ALL).

“We were blindsided, because Ethan hadn’t been sick, andhe had no symptoms. But multiple blood tests showed hiscounts were really high,” says his mother, Sharon. “Wecame to UNC that Sunday, and Ethan immediately beganchemotherapy treatments that same evening. Myhusband Rick and I asked lots of questions because wedidn’t know anything about Ethan’s disease.”

Pediatric oncologist Patrick Thompson, MD, explainedthat Ph+ ALL is a rare chromosomal form of leukemia,and that Ethan and his family were at the beginning of along, hard journey. And Thompson was right. Ethan soonlost his hair, and he was frequently nauseous or sick dueto the many medications he took. Since he was unable toattend school, he missed being with his friends, and hewas concerned about falling behind in his academics.

“My parents arranged to have a homebound teacher workwith me three hours a week,” Ethan explains. “Butotherwise, my mom has become my teacher, classmate,principal, and school bully! Fortunately, I’ve been able tokeep up with my classmates and have made the honor rolleach quarter. I was invited to join the National HonorSociety last semester, so I’m pretty proud of that. Myfavorite subject is medical science, and I think I’d like topursue a career in the medical field.”

THE PATIENTEthan Johnson, 16

PhiladelphiaChromosome-PositiveAcute Lymphoblastic

Leukemia

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Ethan Johnson

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Even though he’s performed well in school, Ethan hasmissed doing all the typical things teenagers do, likeskateboarding, going to the movies, and attending schoolactivities. But his stay in the N.C. Cancer Hospital hasproduced some unexpected surprises.

“Dr. Thompson and I have a great relationship,” saysEthan. “I'm comfortable asking him anything, and I trusthe will always tell me the truth. All of the doctors andnurses have been super nice. I’ve been lucky to find agreat friend who is also a patient and has the samediagnosis I do. His friendship has really helped becausewe feel exactly the same about this whole experience. Ourmoms get us together as much as possible, and we Skypeto play video games together and text a lot.”

Although Ethan’s road to recovery isn’t over, the Johnsonfamily continues to move forward and has become closeras a result of his illness. “I have a lot of nervousness aboutthe unknown, and at times, I’ve been scared I was goingto die,” Ethan says quietly. “But my parents have reallyhelped me through those worries. They tell me they chosemy name – Ethan Asher – because it means ‘strong andhappy,’ so I try to be. I have faith that God will take care ofme and help me through this part of my journey.”

There’s the saying that,“plans are made to bebroken.” But according toDamonte Stackhouse, hisplans haven’t been brokenby cancer; they’ve justbeen put on hold.

In November 2015,Damonte wasn’t feeling well and went to his localemergency room in Fayetteville, N.C. After extensivetesting, he was transferred to the N.C. Cancer Hospital,where he was diagnosed with Acute LymphoblasticLeukemia (ALL).

“I felt this wave of emotions: shock, hurt, worry, anger. Ijust couldn’t believe it,” Damonte says. “I didn’t knowanything about the disease; in fact, I didn't even thinkcancer was real. When they told me I have ALL, I wasafraid I was going to die.”

Damonte’s oncologist, Katarzyna Jamieson, MD, hasbeen with him every step of the way, through multiplerounds of inpatient chemotherapy, as well as a recent

bone marrow transplant. “She told me the treatmentswould make me very sick, but until you actually gothrough it, you just don’t realize how di!cult it will be,” heexplains. “My hair fell out, I lost weight, I had no energy…it was really awful.”

The e"ects of cancer have been more than just physicalfor Damonte. He says feelings of isolation – of being awayfrom family, friends and home – were beginning tooverwhelm him. That is, until Lauren Lux stepped in.

“Lauren listened to me, and she understood myfrustration about having to stay in the hospital for such along time, disconnected from my life and the people Ilove,” says Damonte. “She’s been a great sounding boardwhen I’ve needed a friend. Plus, she’s done some reallynice things for me, like surprising me with my favoritemeal for dinner, taking walks with me, even providing gascards through the Be Loud, Sophie! Foundation so mygirlfriend, De’Sha, could come visit me while I’m in thehospital. Her kindness has been very encouraging.”

Damonte’s home-away-from-home for the next fewmonths will be the SECU Family House, and if all goesaccording to plan, he’ll be home for the holidays. While hehas struggled with the loss of his independence duringhis illness, he says the time he’s spent at the N.C. CancerHospital has given him a new perspective on life. Prior tohis illness, he had been at a crossroads, not sure whetherhe wanted to attend college or to enlist in the U.S. Navy.But during the quiet moments in his hospital room,Damonte decided it’s time to get serious about his future.

“I want to continue my schooling and enroll incommunity college so I’ll have career options. Cancer hasdefinitely caused me to re-evaluate my life, and I don’twant to waste any more time.”

THE PATIENTDamonte

Stackhouse, 19Acute Lymphoblastic

Leukemia (ALL)

Damonte Stackhouse

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Caryn Hertz, MD and Larry Marks, MD

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The old saying that,“great minds thinkalike” is particularlytrue in the case ofLarry Marks, MD, and

Caryn Hertz, MD. The two met asstudents at The Albert NerkenSchool of Engineering at The CooperUnion for the Advancement ofScience and Art in Manhattan. “Wewere both chemical engineers, andafter finishing at Cooper Union, wemutually decided to attend medicalschool,” says Hertz, an associateprofessor of anesthesiology at UNC.“We were fortunate to have thatopportunity.”

“Fortunate” is a word Hertz andMarks use frequently when referringto their lives as a family and asphysicians. “We’ve got three healthy

sons, careers we love, and awonderful network of friends andloved ones here in Chapel Hill,”explains Marks, a UNC Linebergermember and chair of RadiationOncology at the UNC School ofMedicine. “We have been blessed,and we feel a responsibility to giveback in gratitude.”

Hertz and Marks are extremelyactive in a variety of non-profits andcharities, serving on various boardsand o!ering financial support totheir alma maters, public radio, theMS Society, and their localsynagogue, just to name a few. “Weboth grew up in New York, backwhen there was a sense ofcommunity and people helped eachother,” Hertz says. “We’ve tried topass that mentality on to our boys, to

show them the power ofvolunteerism and philanthropy andto practice what we preach.”

Not long after joining the radiationoncology faculty at UNC, Marks wasinvited to a UNC Linebergerfundraiser, where he was introducedto many of the donors who supportour cancer center research. “They area very committed group, and it onlymade sense that Caryn and I wouldjoin them in giving to the institutionthat employs us, provides state-of-the-art cancer care, and treats allpatients, regardless of their ability topay. You know, Caryn and I are verylucky to do what we do, and afterworking with cancer patients all day,I’m humbled and grateful at thesame time. We’re just happy to beable to help.”

FACULTY PROFILE: DRS. MARKS AND HERTZ PAY IT FORWARD

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When cancerstrikes, patientsoften tell usthey have achoice to make:

they can become bitter, or they canbecome better. Thankfully, BethQuinn chose the latter.

A banker, mother, grandmother,community volunteer and friend,Quinn had always been physically fitand proactive with her health. Butover a period of months, she beganhaving abdominal pain and bloating,going to various doctors todetermine the cause. On December23, 2013, Beth went into surgery tohave her gall bladder removed, andwoke up to the news that she hadstage IV ovarian cancer.

“We will continue tofight cancer throughour support of Dr.Bae-Jump’s work.We have to find acure for this disease.”

– Beth Quinn

Because there are no screenings forovarian cancer, and women aretypically asymptomatic until thedisease has advanced, Beth was

unaware of her illness. Her bestfriend, Mary Barto, agreed that thiswas unacceptable, and the two ofthem partnered with another closefriend, Tracy Brown, to do somethingabout it. They formed She ROCKS, aWilmington-based organizationdedicated to raising funds forovarian cancer research andproviding local support to patientsa!ected by all cancers.

Funds raised by She ROCKS godirectly to UNC Lineberger to fundthe ovarian cancer research of UNCLineberger member Vicki Bae-Jump, MD, PhD, as well as to patientsupport programs at Quinn’scommunity hospital, Zimmer CancerCenter. To date, the group hascontributed more the $170,000 toBae-Jump’s work.

In recognition of Quinn’s investmentin research and her confidence in theongoing mission of UNC Lineberger,Paola Gehrig, MD, professor anddirector of UNC GynecologicOncology, joined Bae-Jump inmaking a surprise announcement onSeptember 7 during the 3rd AnnualShe ROCKS Fundraiser inWilmington, NC. “UNC Linebergeris pleased to name one of the Bae-Jump lab spaces in our cancer centerbuilding in Beth’s honor,” Gehrig andBae-Jump shared with more than700 attendees at the WilmingtonConvention Center. “As Bethcontinues to fight ovarian cancer,The Beth Quinn Lab will be aconstant reminder of the importanceof our work and a meaningful tributeto a brave cancer center advocateand friend.”

LAB NAMING HONORSSHE ROCKS FOUNDER

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Vicki Bae-Jump, MD, PhD, and SheROCKS co-founder Beth Quinn outsidethe lab named in Beth’s honor.

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O U R D O N O R S

Major gifts are critical to UNCLineberger’s ability to recruit andretain the very best minds in thecancer field, invest in high potentialresearch, provide innovative patientcare and support programs, andultimately find cures. Our deepestappreciation is extended to thefollowing donors who have madegenerous commitments this year.

$1,000,000+Dr. and Mrs. Kenneth A. Williams toestablish the Ken and CherylWilliams Fund for VentureInititatives, a commimtment tosupport unrestricted research at thediscretion of the Director of UNCLineberger. In recognition of thishistoric commitment, the N.C.Cancer Hospital Lobby was namedin memory of the Williams’ son,Tony.

$100,000 – $999,999Mr. Padrick Barrett and Dr. PhongNguyen to name mammographywaiting room in memory of Dr. Minhthu Nguyen.

Howard Hughes Medical Institute to support the research of Dr. James Bear.

Mr. and Mrs. George W.Loewenbaum to support theresearch of Dr. Charles Perou.

She ROCKS, Inc. to support theovarian cancer research of Dr. Vickie Bae-Jump.

Triad Foundation to support a cancer screening initiative inMecklenburg County.

The V Foundation to honor founding board member, NickValvano, in support of the research of Dr. Charles Perou.

Vs. Cancer Foundation to supportpediatric immunotherapy clinicaltrials and to provide supportive careservices for pediatric patients andfamilies.

$50,000 – $99,999An Anonymous Donor to supportpriority areas where the need isgreatest through the matching giftchallenge.

Atlantic Corporation ofWilmington, Inc. to sponsor the 11thAnnual Fast Break Against Cancer inhonor of Coach Roy Williams and tosupport breast cancer research.

Estate of Mr. Lovick P. Corn tosupport the pediatric oncologyresearch of Dr. Barbara Savoldo.

Estate of Gilda J. Cree to supportleading-edge cancer research.

The Blue Ribbon Run to supportscientific research to help betterunderstand, diagnose, treat and curecolon cancer given in memory ofJulie M. Brown and Christina M.Gianoplus.

Boddie-Noell to support cancerresearch, treatment and outreachprograms through the Blue Ribbon Gala.

!"#$%!"#& UNC LINEBERGER MAJOR GIFTS AND PLEDGES

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Mr. and Mrs. Earl Chesson tosupport the Gail Whisenant TowneEnowment Seed Grant Fund forCancer Research.

Mr. and Mrs. William E. Graham IIIto support priority areas where theneed is greatest through thematching gift challenge.

The Holly Project

Dr. Jennifer Hunter-Yates and Mr.Philip G. Yates to support coloncancer research.

$25,000 – $49,999Mr. and Mrs. Robert E. Barnhill, Jr.to support the Barnhill Seed GrantFund for Cancer Research.

Mr. and Mrs. B. Mayo Boddie tosupport “The Holly Project”benefiting pediatric cancer patientsand families at the N.C. CancerHospital.

Mr. and Mrs. Stephen A. Capps tosupport the Stephen Allen Cappsand Jan Rowe Capps Fund forCancer Patient and Family Support.

Estate of Ms. Margaret V. Fisher tosupport pediatric oncology research.

Carlson Family Foundation tosupport the cancer research projectsof Dr. Peter Voorhees and Dr. Tom Shea.

Constellation Brands to supportCorona Cares benefitting patient andfamily supportive care services at theN.C. Cancer Hospital.

Dr. Krista K. Ingle and Mr. RichardL. Ingle to establish the Robert LeeIngle Colorectal Cancer InitiativesFund.

McMichael Family Foundation onbehalf of Mr. and Mrs. Andrew M.Miracle to support priority cancerresearch and care programs wherethe needs are the greatest in honor ofMr. and Mrs. William E. Graham III.

Mr. R. Owen Mitchell* to supportthe 11th Annual Fast Break AgainstCancer in honor of Coach RoyWilliams.

Oak Foundation to assess andimprove the psychological, socialand emotional support provided topediatric bone marrow transplantpatients.

Dr. and Mrs. William A. Sollecitoto support pediatric oncologyclinical trials.

Dr. Michael A. Stegman to supportthe Nancy W. Stegman Fund for New Ideas in Cancer Research.

Wells Fargo to support cancerresearch, treatment and outreachprograms through the Blue Ribbon Gala.

Mr. and Mrs. J. Cross Williams, Jr. to support priority areas in cancerresearch and care where the need is greatest.

Mr. and Mrs. John D. Woerner tofund the Betty and Otto WoernerEndowment Fund for Patient andFamily Support.

* deceased

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Memorial Tributes made in memory of…We are grateful to the many familieswho, having lost a loved one listedbelow, suggested that family andfriends honor the deceased bymaking contributions to supportcancer research and care at UNCLineberger.

Boyce Lineberger AnsleyGeorge S. Blackwelder, Jr. Austyn Byrd Charlotte H. Cavoores Robert "Brent" Drum Je!rey Ann Hall Evans Oscar "Harris" Ford III Kathleen "Kathy" A. Frewerd Tira Gillig Michelle Greenwood Martin "Marty" Havens Robert "Bob" Peverley Hukill, Jr. Robert Dale John Jamie Lynn Shaver-Mayberry Teresa Dawson McBride Dean "J.R." Lawrence Milani, Jr. Minhthu Nguyen Julieanne Phaneuf Welshie Potts Dean Rivenbark Ann Jeryl Savage John F. Spencer Donald F. Swain Mark Turo! Peter Walters William "Chip" Bainster Wood, Jr. Edwin “Buz” Yarter

UNC Lineberger lost adear friend andcolleague, MichaelO’Malley, PhD, onJune 24, 2015.

Michael served as the associatedirector of UNC LinebergerComprehensive Cancer Center andcommitted over 30 years of serviceto the state of North Carolina. Anexceptional leader, many knew himas a great “connector,” and he wasbeloved by everyone he connectedwith at UNC. Hundreds attended amemorial service to honor this well-known teacher and mentor.

In Michael’s memory, the MichaelStephen O’Malley Cancer PreventionAward was created at UNCLineberger. A fitting tribute toMichael, this annual awardcompetition will ensure thatMichael’s legacy and passionate life’swork continues for years to come by

recognizing excellent student workfocused specifically on cancer andpopulation sciences.

“I am deeply moved by the manygifts that have made this fundpossible, and so many continue tohonor Michael through theirphilanthropy. His kindness, wit, andhumor are truly missed not only byme but countless others associatedwith UNC Lineberger and beyond,”says Nadine O’Malley, Michael’sbeloved wife. “This annual award andso many other daily reminders ofMichael help to celebrate hisremarkable life.”

For more information about how tomake a memorial gift, visitwww.unclineberger.org/michael ormail a check to UNC LinebergerComprehensive Cancer Center, CB#7295, Chapel Hill, NC 27599. Please make checks payable to UNC Lineberger.

MICHAEL STEPHEN O’MALLEY MEMORIAL TRIBUTE AND AWARD

O U R D O N O R S

Shelton Earp, MD, with Michael O’Malley, PhD

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“Look in thedictionary for thedefinition of theword ‘NorthCarolinian’ and

you might see a photo of my parents,William ‘Dubba’ Grimes Clark IIIand Gray Proctor Clark,” laughs GrayClark Stoughton. “Dubba grew up inTarboro, attended Georgia MilitaryAcademy, and then became a true-blue Tar Heel as an undergraduate atUNC-Chapel Hill. That’s where hemet my mother, and they fell in love.”

The couple married after graduationand moved back to Tarboro, whereDubba joined the family farmingbusiness, Clark Industries. Theywere active citizens and taughtdaughter Gray and son Bill theimportance of being involved in theircommunity. “Our parents werewonderful philanthropic rolemodels,” Stoughton says. “Mymother started Tarboro CommunityOutreach, an organization that helpsunderprivileged families inEdgecombe County, and she servedas the first female Senior Warden atCalvary Episcopal Church inTarboro. Mom loved helping others.”

“Our parents weremarried 52 years and did everythingtogether; they weresoulmates and bestfriends,” saysStoughton. “Wecelebrated their 50th weddinganniversary on an African safari.”

Stoughton’s father was equallydetermined to make his home state abetter place for everyone. He wasinvolved in politics at the local andstate levels and led UNC’seducational foundation during thetime that the Dean E. Smith Centerwas being built. “Dubba contributedin so many ways, and always quietly,without fanfare,” explains Stoughton.“In fact, he played a big part infunding the startup of the SECUFamily House. It was a cause nearand dear to his heart.”

Dubba and Gray joined the UNCLineberger Board of Visitors, and in1996, they started the William G.Clark III Fund to help families withtransportation and lodging costsassociated with cancer treatment atUNC. After his passing in 2008, fourof Dubba’s friends jointly gave$350,000 and raised another$475,000, naming the educationroom of the Patient & FamilyResource Center in the N.C. CancerHospital in his memory. Meanwhile,

Gray made frequent tribute gifts toUNC Lineberger in memory offriends and loved ones but never toldanyone. “She was very humble, andshe didn’t want the recognition,”Stoughton says.

A few years ago, Gray’s health beganto decline, and in June 2016, she wasdiagnosed with stage IV pancreaticcancer. She passed just days later atthe age of 81. Stoughton and herbrother have chosen to carry on theirparents’ legacy by serving on UNCboards – Stoughton at Lineberger,Bill at the University – and makinggifts to their father’s fund every year.

“Bill and I know what UNCLineberger means to our family,especially after experiencing cancerfrom a patient and familyperspective,” says Stoughton. “It’smade us think about the researchand the work that is taking placehere, and it’s made us have a newappreciation for the cancer center. Iknow our support of Linebergerwould make our parents proud.”

CLARK FAMILY PHILANTHROPIC ROOTS RUN DEEP

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Director’s Circle$1,000,000+Dr. and Mrs. Kenneth A. Williams

$100,000-999,999 Mr. Padrick Barrett Mr. and Mrs. Thomas N. Chewning Estate of Gilda J. Cree Mr. Bruce C. Gottwald, Jr. Howard Hughes Medical Institute John William Pope Foundation Mr. and Mrs. George W. Loewenbaum,

Waterproof Foundation, Inc. 11Dr. Phong Nguyen She ROCKS, Inc. Vs. Cancer Foundation Triad Foundation, Inc.

$50,000-99,999 Mr. and Mrs. Russell M. Carter, Atlantic

Corporation of Wilmington, Inc. 11Blue Ribbon Run Mr. and Mrs. Earl G. Chesson Crown Imports Estate of Mr. Lovick P. Corn Mr. and Mrs. William E. Graham III 13Dr. Jennifer M. Hunter-Yates and

Mr. Philip G. Yates Kenan Family Foundation The Titmus Foundation, Inc. 26Mr. and Mrs. Robert W. Winston III

$25,000-49,999 Mr. and Mrs. Edward S. Barclay, Jr. Mr. and Mrs. Robert E. Barnhill, Jr.,

Barnhill Family Foundation 20Blue Cross & Blue Shield

of North Carolina 15Mr. and Mrs. B. Mayo Boddie, Sr. Owen Mitchell Foundation Fund at the

Calgary Foundation Jan and Steve CappsCarlson Family Foundation 12

Mr. and Mrs. Neill A. Currie II 12Estate Of Margaret V. Fisher Dr. Krista K. Ingle and Mr. Richard L. Ingle Mr. and Mrs. Kenneth B. Lee 11Ms. Sterling K. McCracken Mr. and Mrs. Andrew M. Miracle,

McMichael Family Foundation New Dixie Oil Corporation Oak Foundation Dr. and Mrs. William A. Sollecito Dr. Michael A. Stegman 11Wells Fargo Mr. and Mrs. J. Cross Williams, Jr. Mr. and Mrs. John D. Woerner

Director’s Club$10,000-24,999 Mr. and Mrs. Douglas E. Anderson 24Mr. and Mrs. Robert A. Baillie 19Chapel Hill Breast Cancer Research Found 18Coastal Beverage Company, Inc. Mr. and Mrs. G. Munroe Cobey Mr. and Mrs. Allan E. Cohen Mr. and Mrs. R. Michael Condrey Mr. and Mrs. Herman Cone III 18Mr. and Mrs. Gerald Cox Mr. and Mrs. Donald W. Curtis, The Curtis

Foundation, Inc. 14Mr. Denis R. De St. Aubin and Mrs. Margaret

W. de St Aubin, Wren Foundation, Inc. Elizabeth Dalton Averett Foundation Sports Endeavors, Inc. 11Flagler System, Inc. Dr. Mel W. Fryar Dr. Mark L. Graham II and

Dr. Laneta Dorflinger The Reverend Roxane S. Gwyn and

Mr. Owen Gwyn, Jr. Mrs. Alice L. Harney 17Jernigan Oil and Propane Mr. and Mrs. Donald J. Kabat Ms. Sterling H. Kenan Ms. Ae R. Kim Dr. Eric H. Lai and Dr. Myla Lai-Goldman Ms. Alice L. Lehman

Long Beverage, Inc. 11Mr. and Mrs. James W. Mann Ms. Mary Ann Maxwell Mr. and Mrs. W. G. C. Mitchell Dr. Martin J. Murphy, Jr. and

Dr. Ann Murphy NIEHS Mr. and Mrs. Dean E. Painter, Jr. Mr. and Mrs. Michael K. Painter Mr. and Mrs. D. Wayne Peterson 12Quality Oil Company LLC Mrs. Marlene W. Ri!in Ms. Ruth B. Roth and Family Mr. and Mrs. George Rountree III Sailfish Capital, LLC Ms. Nancy W. Sample Sampson-Bladen Oil Company, Inc. Mr. and Mrs. Bennett B. Sapp 22Mrs. Judith G. Seagroves Mr. and Mrs. Cecil W. Sewell 18Mr. and Mrs. Edward C. Smith, Jr. 16The Boddie-Noell Foundation The Nickolas Bunn Boddie, Sr. and

Lucy Mayo Boddie Foundation Mrs. Rebecca S. Thompson 11UNC Men's Basketball Mr. and Mrs. Braxton D. West Mr. Clarence E. Whitefield Carolina Inn

Lineberger Leaders$5,000-9,999 Mr. Daniel M. Armstrong III Mrs. Mary P. Arney 16Mr. and Mrs. Moses Awe Mr. and Mrs. Zack H. Bacon, Jr. 20Anonymous 12Mr. and Mrs. F. James Becher, Jr. 12Ms. Jacqueline C. Beecher Ms. Dianne Bertsch Mr. C. Munroe Best, Jr. 17Mr. and Mrs. Bruce A. Biggs 14BookMark My Word 13

!" U N C L I N E B E R G E R C O M P R E H E N S I V E C A N C E R C E N T E R

O U R D O N O R S

HONOR ROLL LIST OF DONORS Each dollar given to UNC Lineberger is meaningful, and we are deeply thankful for the 7,066 donors who contributed$16,191,897 to our cancer center in the past year. Private support enables us to significantly increase the pace of discoveryand pioneer new approaches to care, bringing us closer to our ultimate goal of making all types of cancer curable. Yourgenerous contributions are making a di"erence every day in laboratories, clinics, hospital rooms and communitiesthroughout our state. Thank you for sharing our commitment to fighting cancer.

The lists in this honor roll record the names of those Lineberger Leadership Partners who have led with gifts andpledges of $1,000 or more to UNC Lineberger this fiscal year (July 1, 2015-June 30, 2016). To view this list online, pleasevisit www.unclineberger.org/honorroll.

We have noted those generous supporters who have contributed as Lineberger Leadership Partners for at least 10 Years.We are especially grateful for their loyalty to UNC Lineberger and dedication to helping end cancer.

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Mr. and Mrs. R. Alfred Brand III, Dalton-Brand Foundation, Inc. 19

Mr. F. Cooper Brantley Carolina Premium Beverage, LLC Mrs. Polly P. Carter 12Mr. and Mrs. Thomas F. Chapman Mr. Andrew B. Church and

Ms. Joni L. Walser Mr. and Mrs. James E. Clement, Jr. 11 Mr. Haywood D. Cochrane, Jr. Mr. and Mrs. Je!rey C. Dean Dean's DreamMrs. Joann Rivenbark Dual Comfort Heating & Air Conditioning,

Mr. and Mrs. Tom E. Pilkington Coca-Cola Mr. and Mrs. James M. Emanuele Mr. and Mrs. Jonathan B. Fassberg Ms. Mia H. Garciaparra,

Mia Hamm Foundation 14Genentech, Inc.Ms. Joan H. Gillings Mr. and Mrs. Lawrence J. Goldrich 29Stan and Maureen Greenspon Mr. and Mrs. David A. Groves Dr. James A. Harrell, Sr. Hatteras Venture Partners Ms. Anna R. Hayes 31Howard Perry & Walston Mr. and Mrs. Thomas W. Hudson, Jr.,

Hudson Foundation 19Illumina, Inc. Jazz Pharmaceuticals Mr. and Mrs. Je!rey A. Kaufman 10KPMG Foundation Matching Gifts Laboratory Corporation of America LICKIN’ LEUKEMIAMrs. Ann P. Longley 25Mr. and Mrs. James A. Lucas, Jr. Mr. and Mrs. Hal L. McAdams, Jr. Mr. and Mrs. William O. McCoy Dr. and Mrs. Hamilton W. McKay, Jr. 30Mr. and Mrs. Emmett L. Mitchell III Mr. Thomas Mohr Mr. and Mrs. Bryan A. Morris 13Mr. and Mrs. Patrick F. Nash Ms. Josephine W. Nixon Mr. and Mrs. Larry J. Noe Novo Nordisk Pharmaceuticals O. L. Pathy Family Foundation Performance Automall, Inc. 11R.H. Barringer Distributing Co. Mr. and Mrs. W. Trent Ragland III Mrs. Pearl F. Schechter, Schechter

Foundation 29Shelco LLC Mr. and Mrs. John M. Silverstein 19Dr. James D. Sink Sisters Inspiring Sisters, Inc. Mr. J. Troy Smith, Jr. Southern States Subaru Mr. and Mrs. Verner E. Stanley, Jr. 22Ms. Dale A. Strickland 28

Mr. George A. Sywassink The Market Express, Inc. Mr. Clay B. Thorp and

Ms. Laura E. Francis-Thorp Estate of W. Trent Ragland, Jr. 24Mr. and Mrs. Thomas C. Watkins Dr. Moses Watson III Wells Fargo Advisors Mr. William D. Whisenant and

Ms. Kelly L. Ross Mr. and Mrs. Sydnor M. White, Jr. 29Mrs. Margaret C. Williams, Chaucer

Charitable Foundation 13Mr. and Mrs. Charles M. Winston, Sr. 16Mrs. Betty M. Woerner Zeta Tau Alpha Foundation 23

Lineberger Advocates$2,000-4,999 Mr. and Mrs. James M. Adair Agilent Technologies Alexion Pharmaceuticals Mr. and Mrs. Benjamin F. Anderson, Jr. Mr. and Mrs. John W. Andrews AstraZeneca Pharmaceuticals Bank of North Carolina Mr. and Mrs. Robert E. Barnhill IIIBB&T Mr. and Mrs. Robert Belden Mr. and Mrs. Victor E. Bell III,

Bell Family Foundation 14Mrs. Joyce D. BellMr. William F. Black 25Mr.* and Mrs. George S. Blackwelder 16Mr. and Mrs. Norman E. Block Mr. and Mrs. W. Brad Bobbitt Ms. Joan P. Boone 16Mr. and Mrs. George W. Boylan Mr. and Mrs. John R. Bratton Lieutenant Colonel and Mrs. C. Ray Brinn Mr. and Mrs. S. M. H. Brown Mr. and Mrs. Richard F. Bruch Mr. and Mrs. Clay A. Brumbaugh Mr. and Mrs. G. Ronald Buchanan Mr. and Mrs. John W. Burress III 22Burroughs Wellcome Fund 13Mr. Thomas E. Capps Mr. and Mrs. Sam Q. Carlisle II Mr. and Mrs. George W. Carr III 21The Honorable Narley L. Cashwell, Sr. Chapel Hill Fire Fighters Association Mr. and Mrs. Arthur W. Clark 28Mr. and Mrs. John D. Clark Compare Foods Ms. Christine H. Copley Mr. and Mrs. Glenn D. Corley 10Mr. and Mrs. Marion A. Cowell, Jr. The Reverend Margaret G. Crandall and

Mr. Richard W. Crandall 12Mr. and Mrs. Robert W. Crumley Mr. and Mrs. John H. De Carlo 15Ms. Betty Jean H. Deitz

Ms. Veronica A. DeLario Dr. and Mrs. Joseph M. DeSimone Mrs. Mary-Jarvis Duerson 12Ms. Sally T. Earnhardt Dr. H. Shelton Earp III and

Dr. Jo Anne L. Earp 17Mr. and Mrs. Robert C. Eubanks, Jr. 15Dr. and Mrs. John P. Evans 10Mr. and Mrs. Edward S. Finley, Jr. 24Mrs. Marjanne G. Foster 19Ms. Edith Lee B. Garrett Ms. LaBrenda Garrett-Nelson Dr. and Mrs. Robert M. Gelfand GeneCentric Diagnostics, Inc. Ms. Patricia J. Gerrick Ms. Terri S. Giles Grand Chapter Order of the Eastern Star Mr. Joseph W. Grier III and

Ms. Margaret A. Brookshire Mr. and Mrs. K. Scott Griggs Mr. Norman Grimes Mr. and Mrs. R. Gordon Grubb 10Dubs for a Cause Mr. and Mrs. Cyrus S. Hapgood, Jr. Dr. and Mrs. James A. Harrell, Jr. Mr. and Mrs. James F. Harrell Mr. and Mrs. Cecil W. Harrison, Jr. 19Mr. and Mrs. John L. Hatcher Mr. and Mrs. Donald C. Hiscott Mr. Lawrence C. Ho! Mr. Dale Hollingshead Holmes Oil Company Mrs. Dorothy B. Hubbard 13Mr. and Mrs. David F. Hurst Mrs. Carol C. Hutchins Mr. John V. Hyer and Ms. Laura T. Jensen 11iHeartMedia Ms. Donna W. Ivey Mr. and Mrs. Je!rey W. Johnson Mr. and Mrs. Marvin R. Joyner Mr. Thomas J. Kean Mr. and Mrs. Clarence H. Keller 20Kerr-Vance Academy Class of 2010

in memory of Austyn Byrd Mr. Harrison H. Kim Mr. and Mrs. D. Gray Kimel, Jr. Dr. and Mrs. John R. Kirkland Hodge and Jean Kitchin Mrs. Joyce R. Kline Ladies Auxiliary VFW Dept. NC 17Mr. Charles N. Landen, Sr. 14Mr. and Mrs. James G. Leach Dr. Peggy Leatt and Dr. George H. Pink Lee-Moore Capital Company 13Ms. Carolyn S. Littles Ms. Judith P. Lotas Mr. and Mrs. Richard B. Lupton 20Mr. and Mrs. John C. Mansfield Dr. Lawrence Marks and Dr. Caryn M. Hertz Mrs. Emily W. McHardy Ms. Katherine F. McKenzie Mr. and Mrs. Ronald B. McNeill 19Medical Foundation of NC, Inc. Mr. and Mrs. Charles G. Meyer, Jr.

2 0 1 5 – 2 0 1 6 D O N O R H O N O R R O L L !"

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O U R D O N O R SMr. and Mrs. Thomas D. Mincher, Sr. 22Mr. and Mrs. Daniel K. Moore, Jr. Dr. Susan L. Hogan and

Mr. Dominic T. Moore 11Dr. Paul S. Muenzner Mr. Craig V. Murray, Jr. Dr. and Mrs. Robert E. Taylor, Murrill

Foundation, Inc. 10Dr. and Mrs. Hyman B. Muss Mr. Je!rey P. Naper Ms. Judith O'Brien and Ms. Megan O'Brien Mr. and Mrs. William A. Olsen, Jr. Mrs. Nadine S. O'Malley 16Dr. and Mrs. Joseph S. Pagano 13Mr. and Mrs. William G. Pappas 12Ms. Elizabeth K. Pate Ms. Bettina Patterson Mr. and Mrs. Warner B. Perry Mr. and Mrs. William P. Pope 16Mr. and Mrs. John P. Preyer R.A. Je!reys Distributing Co. of Raleigh Mr. and Mrs. Anthony E. Rand Mr. and Mrs. Walter Rand III Mr. and Mrs. Lawson A. Rankin, Jr. Mr. and Mrs. Gordon D. Rapp River Landing Golf Association for Ladies Mr. William T. Roberts, Jr. 16Dr. Joshua C. Rose and Dr. Rebecca B. Rose Mr. Charles J. Wolfe, Jr. and

Mrs. Sandra R. Roth 13Dr. and Mrs. Charles J. Sawyer III Mr. Harry B. Schi!man Mr. William J. Seagroves Skyland Distributing Co. Inc. Ms. Ellen S. Small Southern States Logistics Dr. Debra W. Stewart and

Mr. Edwin M. Speas, Jr. 18Mr. and Mrs. William N. Starling, Jr. Mr. and Mrs. Thomas F. Stoughton Mrs. Elaine O'Neil Dr. Lishan Su Mr. and Mrs. W. Franklin Sutton Mr. and Mrs. Michael A. Swann Mr. and Mrs. Je!rey S. Taylor The Educational Foundation, Inc. 12The Farm Party Mr. and Mrs. James W. Thompson Mr. and Mrs. Je!rey K. Tillman 11 Triad Golfers Against Cancer 10Mr. Michael Tribble and

Mrs. Sayre Lineberger 13United Beverages of NC, LLC Mr. and Mrs. Douglas A. Vaughn 11Mr. and Mrs. Robert Vermette Ms. Cynthia G. Vogler W. Trent Ragland, Jr. Foundation Mr. Edward D. Wall Joe and Nancy Warner Mr. and Mrs. David C. Waters Mr. and Mrs. Harroll H. Weaver Mr. and Mrs. Joseph R. Westmoreland II Mr. and Mrs. James G. Whitton, Sr. 20Ms. Clyde B. Williams

Mr. and Mrs. Alfred Williams IV Mrs. Betsy C. Williams Mr. and Mrs. Peter S. Wilson Mrs. Cheryl Wist

Lineberger Club$1,000-1,999 Dr. and Mrs. William B. Abernethy, Jr. 25Mr. Michael Ackerman,

Quagga Accessories, LLC Vicky Adams and Cassie Adams Ms. Margaret P. Allen Atma Hotel Group Ms. Alexa S. Aycock Ms. Shannon Baker Mr. and Mrs. Stephens L. Baldwin, Jr. 18Mr. F. Marion Barnes Mr. and Mrs. Martin A. Baucom Ms. Cathy Baxter Dr. James H. Fryar III and Ms. Berry B. Bean Mr. John W. Becton and

Ms. Nancy B. Tannenbaum Dr. James W. Begun Mr. James C. Bivens, Sr. and

Mrs. Cathy F. Bivens Mr. David Black Ms. Katelyn P. Blanchard Dr. M. Robert Blum 10Ms. Joan P. Boone 16Mr. and Mrs. Douglas W. Booth 28Mr. and Mrs. Randall A. Bowling Ms. Linda M. Bowman Dr. and Mrs. Thomas G. Braun Mr. and Mrs. Milton S. Brown III 17Mr. David C. Bryan Mr. and Mrs. Harry M. Bryant, Sr. 29Mr. Mark Witcher and Ms. Margaret A. Bush Mr. and Mrs. Michael Cain Mr. and Mrs. Joseph V. Calcutt CAP Community Foundation, Inc. Mr. and Mrs. William T. Carson Mr. and Mrs. Roy E. Cashion Dr. and Mrs. W. Lowry Caudill Mr. and Mrs. George H. Cecil 30Cell Signaling Technology, Inc. Mr. and Mrs. Stewart M. Chisam 12Choate Construction Mr. Charles T. Choplin Mr. Jerry Christopoulos Mr. and Mrs. Paul L. Chused 22Ms. Gray P. Clark* 16Dr. and Mrs. J. Edwin Clement Ms. Sue W. Cole Mr. Frederick H. Cooke Mr. and Mrs. Marshall Y. Cooper, Jr. Mr. and Mrs. James L. Copeland Mr. and Mrs. Jacques Cote Mr. and Mrs. Alexander Coucoulas Ms. Nan V. Crawford 10Mr. Danny B. Crets Dr. and Mrs. Dean Croushore Mr. William R. Cuthbertson, Jr. Mr. and Mrs. Harold E. Daniels, Jr.

Ms. Martha M. Davenport Mr. R. P. S. Davis, Sr. 14Mr. and Mrs. Richard Dean Mr. and Mrs. John F. Deans Mr. and Mrs. Douglas S. Dibbert 11UNC Softball in memory of

Jamie Shaver-Mayberry Mrs. Nancy S. Dowdy 23Ms. Virginia S. Dozier Ms. Cheray Z. Duchin East Village Grill East Wake Football League Dr. Jonathan Flescher and Dr. Susan L. Eder Dr. and Mrs. Chad A. Ellis Mr. Ernest Ellison II Mr. and Mrs. David A. Evans, Jr. Dr. Thomas J. Mercolino and

Dr. Janet L. Evans 10Mr. and Mrs.* H. Spencer Everett, Jr. Mr. and Mrs. J. Michael Fargis Mr. and Mrs. Purvis J. Ferree, Jr. 24Mr. and Mrs. Charles M. Fields Mr. and Mrs. Phillip E. Folger Forest Oak Animal Hospital Ms. Bettie K. Formyduval Ms. Jane L. Fouraker Mr. and Mrs. Douglas E. Frey Dr. and Mrs. Stephen V. Frye Mr. and Mrs. Robert L. Fuerst Mr. Paul Fulton Mr. M. Lee Garrison 23Mr. and Mrs. R. Scott Gaylord Mr. and Mrs. John Goodacre Dr. and Mrs. James O. Goodwin Mr. and Mrs. George D. Gornto 18Mr. J. G. Grout and Ms. Ann V. Langford Ms. Allison R. Guess in memory of Bill Rand Captain and Mrs. Douglas B. Guthe, Jr. Mr. Zebulon Hadley IV Mr. Thomas J. Hall Mr. and Mrs. Walter V. Hall 15Hanover Insurance Group Matching Gifts Mr. and Mrs. Christopher M. Harris Mr. and Mrs. James N. Harris, Jr. Mrs. Thelma W. Hatton Mr. H. Thomas Webb III and

Mrs. Kathryn Heath Mrs. Elizabeth J. Heins 19Dr. Donna F. Helton and Mr. David L. Helton Ms. Mamie H. Henry Mr. William S. Henry, Jr. 22Mrs. Alexandra L. Henson 10He's Not Here, Inc. Mr. John D. Hickok, Jr.,

Hickok Family Foundation Mrs. Marian H. Hicks Ms. Sara S. Hill Mr. and Mrs. Scott Hodgson Mrs. Carolyn M. Hoke Mrs. Lucinda Holderness* Mr. and Mrs. Arthur L. Holmes, Jr. Mr. and Mrs. Arthur L. Holmes, Jr. Dr. and Mrs. W. Borden Hooks, Jr. 13Ms. Lois F. Hope

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Ms. Susan W. Hudson Mr. and Mrs. John C. Hu!ard 16Ms. Catherine Hu!man Mr. and Mrs. John W. Hughes III Mr. and Mrs. J. Edwin Hunter 28Mr. and Mrs. Robert T. Hutcheson Mr. Richard A. Hutchinson, Sr. Ms. Judith R. Ingle Mr. and Mrs. Grady I. Ingle Mr. and Mrs. Robert S. Isner J.M. Davis Industries, Inc. Dr. Lindsey I. James and

Mr. Andrew E. James Ms. K. Eileen Je!erson Dr. and Mrs. Joseph M. Jenkins Dr. Samuel G. Jenkins, Jr. Dr. and Mrs. Joseph M. Jenrette III Johnny T-Shirt, The Carolina Store Mr. and Mrs. Earl Johnson, Jr. 16Ms. Ellen J. Johnson Dr. and Mrs. Richard M. Jordan 17Mr. and Mrs. Robert S. Kadis Kappa Psi Pharmaceutical Fraternity

Beta Xi Chapter Mr. and Mrs. E. Larry Kelly,

Kelly Family Foundation 10Mr. Thomas S. Kenan III Dr. and Mrs. Harold B. Kernodle, Jr. Dr. James Y. Kim Mr. and Mrs. D. Gray Kimel, Jr. Dr. Amy R. Kincheloe and

Mr. Andrew H. Kincheloe Mr. Donald R. King Mr. and Mrs. James L. Kiser Mr. and Mrs. Robert H. Kluttz 16Mr.* and Mrs. Alexander Kosma, Jr. 12Dr. and Mrs. Frederick G. Kroncke, Jr. Mr. and Mrs. Daniel B. Krueger Ms. Susan M. Krupa Dr. Chantale LaCasse Mr. Arnold Lakey 11Dr. and Mrs. J. Michael Lazarus Leeolou Family Foundation Mr. and Mrs. Seymour M. Levin 14Mr. and Mrs. B. Bailey Liipfert, Jr. Mr. Kirt Lindstrom Mr. Mark K. Lipton Mr. and Mrs. Frank H. Livingston 11Mr. William G. Long Mr. Rodney M. Long Mr. David N. Long Mr. and Mrs. Larry H. Loy Dr. and Mrs. Peter B. Lyon 21Mr. G. Peter Macon Mrs. Carolyn S. Maddux Mr. and Mrs. Carl P. Marion, Jr. Mr. and Mrs. Leon C. Marsh Ms. Jane R. McBryde Mrs. Betty Ray McCain 12Mr. Edward C. McCarthy Mr.* and Mrs. Roland P. McClamroch 21Mr. and Mrs. Samuel A. McConkey, Jr. 15

Mr. Dennis M. McGill and Ms. Edwina D. Woodbury 17

Dr. and Mrs. William W. McLendon 18Mr. and Mrs. William E. McMahan Ms. Jane M. McNeer Mr. and Mrs. Harold J. Milholen, Jr. Ms. Beverly S. Mitchell Mr. and Mrs. John G. Mitchell Ms. Betty B. Mittag Mr. and Mrs. Benjamin E. Moore 22Mr. and Mrs. T. Patrick Moore Mr. and Mrs. George M. Moorefield II 18Dr. Cary P. Moxham Mr. and Mrs. Pender Murphy Mr. and Mrs. Sherrill R. Newnam Ms. Carol S. Newnam Nissan North America, Inc. Mr. and Mrs. T. LaFontine Odom Ogden Elementary School Mr. and Mrs. H. Patrick Oglesby 10Mr. and Mrs. S. Theodore Oliver, Jr. Dr. Andrew F. Olshan and

Dr. Linda C. Levitch Mr. and Mrs. Walton O'Neal Mr. and Mrs. William H. Page 22Dr. Susan N. Palmer The Honorable Sarah E. Parker Mrs. Josephine W. Patton 13Mr. James R. Patton, Jr. Mr. John W. Peddycord 19Pierre Fabre Pharmaceuticals Tyler's Taproom, Durham Ms. Laura C. Piver Mr. and Mrs. Mario Poma Ms. Evelyn M. Poole-Kober Dr. and Mrs. R. Kirby Primm Dr. Elizabeth V. Raft Mr. Richard H. Rains Mr. Walter D. Ramberg Dr. and Mrs. Neil A. Ramquist Ms. Jennifer A. Rasmussen Triangle Wine Company Mrs. Donna H. Reynolds Mr. and Mrs. Ralph L. Roberson Mr. Kermit Robinson, Jr. Rocky Mount Academy Dr. John F. Stewart and Dr. Paula R. Rogenes Mr. and Mrs. W. Gerard Rogers Ms. Julia Roseland Dr. Dennis P. Ross Dr. and Mrs. Charles A. Sanders Ms. Donna L. Schmidt Ms. Robin Serody Dr. Martha K. Sharpless Dr. Thomas C. Shea and

Dr. Katherine M. Shea 10Dr. and Mrs. G. Bradley Sherrill R. and E. Allen Family Foundation Ms. Elizabeth A. Silverstein Mr. and Mrs. Herman Simon Mr. and Mrs. William A. Simpson Mr. and Mrs. William A. Smith 14Mr. and Mrs. Henry L. Smith Dr. J. Keith Smith and Dr. Lisa L. Jones Mrs. Linda Smith

The Honorable and Mrs. James C. Spencer, Jr.

Mr. Gordon R. Spencer Dr. and Mrs. Brian Stabler 12Mr. and Mrs. A. Donald Stallings Mr. and Mrs. Joseph W. Stanley 17 Mr. William W. Staton, Jr. 10Mrs. Linda J. Staunch Ms. Laurie M. Stegman Mr. and Mrs. Richard Y. Stevens Mr. and Mrs. David C. Stewart Mr. and Mrs. Norman V. Stockton III 12Mr. and Mrs. James L. Stuart 19Mr. and Mrs. Robert K. Stuart Mr. and Mrs. John L. Sullivan, Jr. SunTrust United Way Campaign Mr. Sean Swanberg Mr. Walter E. Switzer Mr. and Mrs. John D. Swo!ord Mr. and Mrs. John A. Taylor 17Mr. Edmund B. Tazewell III The Dickson Foundation, Inc. 25Mr. and Mrs. Reuben D. Thompson IV Mr. and Mrs. Willis Thompson IV Ms. Mary Frances Thompson Mr. and Mrs. Rick Thompson Ms. Olga B. Thorp Mr. and Mrs. W. Lyndo Tippett Mr. and Mrs. Braxton B. Townsend, Jr. Mr. and Mrs. Christian Heide Trask, Jr. 17Mr. and Mrs. William M. Trott US Foods Variety Wholesalers, Inc. Mr. and Mrs. John H. Vaughan Ms. Natasha A. Vos Ms. Susan J. Voskuil Mr. and Mrs. Paul Walters Ms. Stephanie N. Wangerin Mr. and Mrs. Larry B. Ward Mr. and Mrs. Kevin C. Ward Mr. and Mrs. Thomas C. Watson, Jr. Waverly Hematology Oncology,PA Mr. Patrick B. Weede Mr. Charles L. Weill, Jr. 23Ms. Tina N. Weinberg Mr. and Mrs. A. Bartlett White Ms. Stephanie Widin Mr. and Mrs. Sheldon M. Wiggins Mr. and Mrs. Clarence E. Williams III Mr. and Mrs. Bryan L. Williams Mr. and Mrs. T. Murray Williams 16Mr. and Mrs. John D. Wilson, Sr. 12Dr. Catherine A. Wilson and

Mr. Fletcher N. Wilson Mr. and Mrs. John D. Wilson, Jr. 11 Mr. and Mrs. William W. Wilson,

Wilson Foundation 26Mr. and Mrs. Frederick P. Wood, Jr. Ms. Caterri M. Woodrum Ms. Margie H. Wright Mr. and Mrs. David A. Youngdahl Dr. James M. Zealy* Dr. Robert Zipf Mr. and Mrs. Robert L. Zucker 14Dr. and Mrs. Mark S. Zurawel

2 0 1 5 – 2 0 1 6 D O N O R H O N O R R O L L !"* deceased

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O U R D O N O R S

Anonymous (6)Mr. Benjamin F. Anderson, Jr. and

Mrs. Kathryn Keel AndersonMr. Douglas AndersonMrs. Boyce L. Ansley*Mr. and Mrs. Zack BaconMrs. Joyce D. BellMs. Brenda BensonMr. and Mrs. James C. BivensMr. and Mrs. M.S. “Brick” Brown IIIMr. and Mrs. Clay BrumbaughMr. and Mrs. Harry BynumJan and Steve CappsMr. Thomas E. CappsMr. and Mrs. Thomas N. ChewningMr. Paul L. ChusedMr. and Mrs. Benton F. CliftonMr. and Mrs. Arthur W. ClarkMs. Elizabeth CohenMs. Stephanie B. ColeMr. P. Kim CopsesMrs. Gilda J. Cree*Mr. Arthur S. DeBerryMr. and Mrs. John H. DeCarloMr. Riley DeHart, Jr.Mr. and Mrs. Douglas S. DibbertMr. Albert S. Dillon, Jr.Mr. and Mrs. James B. Dunn, Jr.Dr. H. Shelton Earp, IIIMs. Jane FourakerMr. M. Lee GarrisonMs. Patricia J. GerrickMr. Lawrence J. Goldrich

Dr. and Mrs. James O. GoodwinStan and Maureen GreensponMrs. Harriet GrimmMrs. Julia S. GrumblesMr. and Mrs. R. Gordon GrubbDr. and Mrs. G. Denman HammondMrs. Alice Lineberger HarneyMr. and Mrs. James F. HarrellMr. and Mrs. John L. HatcherMr. David R. Hayworth, Jr.Mr. James T. Hedrick, Sr.Mr. Lee A. HenningsenEd and Carla Herring Mrs. Virginia E. HesterMr. and Mrs. Donald HiscottMrs. Dorothy B. HubbardMs. Susan HudsonMr. John V. Hyer and Ms. Laura T. JensenMs. Lisa P. JacksonMr. and Mrs. Earl Johnson, Jr.Ms. Eli JordfaldMr. and Mrs. Richard KarpMr. and Mrs. Kenneth B. LeeMs. E.H. Sayre LinebergerMr. William G. LongMrs. Carolyn S. MadduxMrs. Betty Ray McCainMr. and Mrs. Ronald McClamroch, Jr.Ms. B. Claire McCulloughMs. Frances Watts McCurryDr. and Mrs. Hamilton W. McKay, Jr.Mr. Zeb Vance McMillan, Jr.Mr. and Mrs. Bryan A. Morris

Mr. and Mrs. J. Harvey Oliver, Jr.Ms. Patricia C. OwensDr. Susan N. PalmerBill and Debbie PappasMr. and Mrs. D. Wayne PetersonMr.* and Mrs. W. Trent Ragland, Jr.Mr. and Mrs. David S. RouthMs. Nancy W. SampleMrs. Adelaide Raye SappDr. Robert E. SevierMr. J. Troy SmithMr. Marty SmithMr. Roger V. SmithMrs. Anna L. StanleyMr. and Mrs. William N. Starling, Jr.Mr. William W. Staton, Jr.Mrs. Catherine StuartMs. Martha K. TesoroMr. James W. Thompson, IIIMr. and Mrs. Walter L. WardMr. Lindsay C. Warren, Jr.Mrs. Charlotte M. WeaverMr. Harroll H. “Nick” WeaverMr. Clarence E. WhitefieldMr. and Mrs. John Cross Williams, Jr.Dr. and Mrs. Kenneth A. WilliamsMr. and Mrs. John D. Wilson, Sr.Mr. and Mrs. Charles M. Winston, Sr.Mr. John Drew WoernerMr. Charles J. Wolfe and Ms. Sandra R. RothMs. Edwina Woodbury and

Mr. Dennis McGill

THE BERRYHILL SOCIETYIn 2003, the Medical Foundation of North Carolina, Inc. created theBerryhill Society to recognize those individuals who have provided forthe School of Medicine through a planned gift from their estates. Thisrecognition society is named for the late W. Reece Berryhill, longtimedean and leader at the School of Medicine.

At UNC Lineberger, planned gifts can leave a legacy in your name orhonor someone important to you. We honor and recognize thefollowing supporters who have generously included UNC Linebergerin their estate plans. We extend a special welcome to our newestmembers, whose names are italicized.

* deceased

Walter Reece Berryhill, MD

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Brigham YoungUniversity’s men’sbasketball coach andpancreatic cancersurvivor Dave Rose

spoke at the 11th annual Fast BreakAgainst Cancer. Hosted annually byUNC men’s basketball coach RoyWilliams, the live auction breakfastevent reached a major milestone in2015, having raised more than $2million over the last 11 years tobenefit cancer research andtreatment at UNC Lineberger.

During the breakfast, Coach Roseshared that his world was turnedupside down when he was diagnosedwith pancreatic cancer six years ago.His plans to coach his team, run abasketball camp and go on recruitingtrips were put on hold by his doctors;extensive surgeries and treatmentsfollowed.

"It was a di!cult time, but I learnedtwo very important things during mycancer journey,” Rose said."Specifically, that I needed to becomea kinder person, and that I had tofind ways to enjoy the remainingtime I have." That same year, Roseand his wife began pursuing otherinterests in addition to sports, likevisiting art museums, traveling toexotic locations and simply spendingquality family time together. “Cancerwas a catalyst for some big, verypositive life changes,” he explained.

Following the close of Rose’s remarksand the completion of the silentauction, Coach Williams and TarHeel broadcaster Jones Angellkicked o" the live auction. Auctionitems included an opportunity towatch a home men’s basketball gamefrom the team bench, a sleepover inthe Smith Center, a cookout withCoach Williams and his team, andmore.

This year's auction also included themost unique item in the history ofFast Break: a Carolina blue o!cechair that was used by Dean Smithwhen the Tar Heel basketball o!ces

were located in CarmichaelAuditorium. The eventual winningbidder at $15,000 was Dr. MarkGraham, a former oncologist at UNCLineberger who is now in privatepractice at Waverly Hematology andOncology. Graham also treatedformer NC State women’s headcoach Kay Yow, and he told thecrowd he plans to keep the chair inhis treatment room for thosereceiving chemotherapy, as a tributeboth to Smith and to Yow’s grace inher own battle with cancer.

At the conclusion of the event, CoachWilliams thanked attendees formaking it possible to surpass his $2 million fundraising goal, whichdirectly benefits UNC Lineberger. A special thanks also goes topresenting sponsor AtlanticPackaging and to all of the generoussponsors for supporting Fast Break.

!!TH ANNUAL ROY WILLIAMS’ FAST BREAK AGAINST CANCER

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Nearly 300 UNCLinebergerComprehensiveCancer Centersupporters gathered

at The George Watts Hill AlumniCenter to hear cancer survivor,former Green Beret medic and third-year UNC medical student EricStrand speak on February 20, 2016,during the 29th Annual LinebergerClub Brunch and Basketball Game.

Strand shared with his audiencewhat he calls a journey of secondchances. The Alabama nativedropped out of high school followinghis sophomore year and beganworking odd jobs, yet still searchingfor a meaningful career. Heeventually got his GED and enlistedin the U.S. Army, finding thatmilitary life agreed with him. Afterbecoming a Green Beret in theSpecial Forces, Strand was selectedto serve as a medic.

“From 2004 to 2009, I was in aconstant cycle of deployment in Iraq,which included three tours of duty in

various parts of the country,” heexplains. “When my overseasresponsibilities ended, I landed atFort Bragg, where I became the pointof contact for the UNC AdvancedMedic Instructor Training (AMIT)program.” From there, he finished hisundergraduate degree, and the pathto medical school quicklyprogressed. “I found the UNC Schoolof Medicine welcoming, even thoughmy age, background and set ofexperiences di!er so much fromother students,” Strand says. “UNChas a good heart.”

Speaking of heart, UNC surgeryresident Shiara Ortiz-Pujols stoleStrand’s heart while she was trainingto become a burn surgeon at theJaycee Burn Center. However, justtwo weeks after the couple wasengaged, and only months beforeStrand was to begin medical school,he was diagnosed with lymphoma.“We were stunned by the news, butwe decided to move quickly and getmarried because we wanted to havechildren,” he says.

Strand spent a year in surgery andtreatment, juggling his illness withhis medical school studies. On themorning he received his finalradiation treatment two years ago, hereturned to the hospital later thatsame day to support Shiara duringthe birth of their daughter, Adelisa.Strand says her arrival marked theend of his treatment and a newbeginning for the couple.

Today Strand is free of cancer, andlooking back, he believes his lifeexperiences have contributed to hissuccess as a medical student and asa future health care provider. “Ibelieve in second chances,” saysStrand. “Life is definitely worthliving.”

Each year, UNC Lineberger hosts theLineberger Club Brunch andBasketball Game, inviting its mostloyal and generous supporters. Weare grateful to Lee-Moore CapitalCompany, Hardee’s, Dual ComfortHeating and Air Conditioning, andUNC Shared Services CenterPharmacy for making the 29thannual event possible.

!"TH ANNUAL LINEBERGER BRUNCH AND BASKETBALL GAME

O U R C O M M U N I T Y

Middle: Eric Strand, his wife Shiara Ortiz-Pujols, and Gwen and Gary Burrell. Right: E.T. and Champ Mitchell

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When she’s not busy coaching the Tar Heels Women’s Basketball Team or writing best-selling books, Coach SylviaHatchell is a strong advocate for UNC Lineberger. Every summer Coach Hatchell opens her Black Mountainblueberry patch to the public and encourages donations to UNC Lineberger in exchange for fresh blueberries.

Now in its sixth year, Corona Cares continues to raise the barthorough their support of the UNC Lineberger ComprehensiveCancer Support Program. During the month of August, NorthCarolina Wholesalers and Corona’s parent company, ConstellationBrands, raised $200,000 for patient and family supportive care atthe N.C. Cancer Hospital. This brings the six year total to $850,000!Left: The women of UNC Zeta Tau Alpha sorority are long-timesupporters of UNC Lineberger. Through the annual Franklin 5kand other fundraising e!orts, the ZTAs have contributed more than$200,000 to UNC Lineberger in their 20 year history!

Everyone knows that the Chapel Hill Fire Department fights fires, but did you know they fight cancer, too? In additionto arranging for the national Pink Heals tour to stop at the N.C. Cancer Hospital, they generously support our patientsand their caregivers through donations to the Patient and Family Resource Center. Thank you CHFD!

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BLUE RIBBON PARTNERS Members of the Blue Ribbon Partnersgiving society are volunteers andorganizations throughout the communitywho host annual fundraising events tobenefit the cancer center. To qualify as aBlue Ribbon Partner, members hostevents benefiting the cancer center for atleast three years, raising $25,000 or moreduring this period.

Bobby F. Garrett Cancer Benefit ConcertBookmark My WordsBoy Scout Troop 845Chapel Hill Breast Cancer ResearchFoundationCocktails for CancerColdwell Banker: Howard Perry andWalstonCorona CaresJohn R. IsnerPedal for PedsRLGALS Swing for the CureSports Endeavors*Tanger OutletsTar Heel 10 Miler/Endurance MagazineTriad Golfers Against CancerUNC Carolina BaseballVs. Cancer FoundationZTA Foundation

* New member

In December, 300 carolers came out in support of the 10th AnnualCaroling for a Cause in Cary. Led by high school senior Ryan Myer, withsupport from Debbie Hodgson, the group raised $7,000 for research atUNC Lineberger. Now, that’s something to sing about!

December marked the 7th Annual Bobby F. Garrett Cancer Benefit, aconcert organized by Dr. Alice Garrett in memory of her husband, Bobby.Since Bobby passed away of a rare head and neck cancer in 2008, Aliceand her daughter, Chaunte, have hosted this concert at the St. MatthewAME Church in Raleigh to support UNC Lineberger.

Whether it’s the delicious North Carolina barbeque, live bluegrass musicor the spectacular silent auction, guests just can’t get enough of TheFarm Party. This special event, hosted by the Teer Family Farm in ChapelHill, has now raised more than $15,000 for UNC Lineberger in its three-year history.

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Below left: In November 2015, more than 70 members and coaches from UNC Men’s Lacrosse andBaseball teamed up in the fight against pediatric cancer. Together, they raised $32,000 through Vs.Cancer Foundation for pediatric cancer research and patient support at UNC Linebeger. These studentathletes are stars on and o! the field!

Above right: The UNC Rowing team selected UNC Lineberger as the beneficiary for their fifth annualErg-A-Thon fundraiser supporting breast cancer research. The athletes set up special rowing equipmentin the Pit and raised $7,610. This year, the team was joined by a few celebrity rowers, including men’sbasketball player Joel James and UNC Student Body President Houston Summers.

For the third year running, Sports Endeavors supported UNC Lineberger through sales of pink itemsduring the month of October on their famed Soccer.com and Lacrosse.com sites. Together, the sitesraised $14,000 for cancer research. Sports Endeavors also partners with the N.C. Cancer Hospitalthroughout the year to provide private, behind-the-scenes tours of their Hillsborough headquarters.

Above left: Hosted in October at the UNC Wellness Center in Cary, the 6th Annual Pedal for Peds raisedmore than $30,000! Spearheaded by UNC Lineberger’s Julie Blatt, MD, and her team of volunteers, thisevent supports pediatric fellowships and other needs at the N.C. Cancer Hospital. Above right: In March, the UNC Women’s Softball team hosted their annual Ovarian Cancer AwarenessDay, honoring former Tar Heel player Jamie Shaver Mayberry. Sadly, Jaime lost her courageous battleagainst ovarian cancer in May.

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Kitty and Ben Anderson Lee and Doug Anderson Jack and Nancy Andrews Mack Armstrong Mary Arney Alexa Aycock Ned and Margaret Barclay Bob and Penny Barnhill Joyce Bell Vic and Mary Grady Bell Bruce and Anna Biggs Jim and Cathy Bivens George and Cynthia Boylan Ray and Gaye Brinn Brick and Mary Craig Brown Henry and Linda Brown Clay and Helen Brumbaugh Barbara and Michael Cain Jan and Steve Capps Sam and Cathy Carlisle Polly Carter Lowry and Suzi Caudill John and Shelley Clark Jim and Louise Clement Munroe and Becky Cobey Sue Cole Mike and Cecelia Condrey Marion and Norma Cowell Nan Crawford Neill and Linda Currie Jay Dalton Denis and Margaret de St. Aubin Margaret and Je! Dean Mary-Jarvis Duerson Bob and Mary Ann Eubanks Ed and Ginger Finley Peter and Kim Fox Bob and Claudia Fuerst Lee Garrett Patricia Gerrick Joan Gillings Bill and Nancy Graham Bob and Kristen Greczyn Joe Grier and Ann Brookshire

Gordon and Sallie Grubb Tommy Hall Alice Harney Jimbo and Lorraine Harrell Jim and Barbara Harrell John and Pat Hatcher Anna Hayes Lee and Brenda Henningsen Don and Brenda Hiscott Dot Hubbard Susan Hudson John and Caroline Hughes Edwin and Louise Hunter Jack Hyer and Laura Jensen Cathy and Buddy Jenrette Earl and Margie Johnson Brent and Dana Jones Bobby and Claudia Kadis JR and Martha Kirkland Hodge and Jean Kitchin Daniel and Katharine Krueger James and Katirie Leach Ken and Frankie Lee Alice Lehman Sayre Lineberger and Michael Tribble

Judy Lotas Carolyn Maddux Jim and Kay Mann Betty Ray McCain Bill and Sara McCoy Peter and Dee Dee McKay Kathy McKenzie Ronnie and Cyndi McNeill Hal and Julia Brent Milholen Tom and Judy Mincher Liz and Andrew Miracle Dan and Fran Moore Bryan and Rebecca Morris Marty and Ann Murphy Patrick and Carol Nash Fountain and Carmen Odom Walton and Helene O'Neal Dean and Lisa Painter

Bill and Debbie Pappas Sarah Parker Josie Patton Warner and Ann Perry Wayne and Billie Ann Peterson Joyce Pope Marilyn and Rich Preyer Tony and Karen Rand Francine and Ralph Roberson George and Sylvia Rountree Lynn and Seth Rudnick Bennett and Raye Sapp Pearl Schechter John and Leslie Silverstein Jim Sink Troy Smith Page and Eliot Smith Edwin Speas and Debra StewartTom and Bonnie Spradling Richard and Nancy Stack Verner and Anna Stanley Linda Staunch Niklaus and Lucy Steiner Richard and Jere Stevens Tommy and Gray Stoughton Dale Strickland Cathy and Jim Stuart Becky Thompson Bo Thorp Clay Thorp and Laura Francis-ThorpJe! and Janis Tillman Douglas and Greyson Vaughn Forrest and Laura Waldon Nancy and Joe Warner Tommy and Boo Boo Watkins Charlotte and Nick Weaver Monty and Nancy White Ken and Cheryl Williams Cross and Anne Williams John and Anne Wilson Charlie and Flo WinstonTracy and Bob Winston Vicki and Russ Winthrop Drew and Tammy Woerner

UNC LINEBERGER BOARD OF VISITORS

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2 0 1 5 – 2 0 1 6 D O N O R H O N O R R O L L !"

UNC LINEBERGER ADMINISTRATION

Norman E. Sharpless, MD, Director ofUNC Lineberger

H. Shelton Earp, MD, Director, UNCCancer Care

Chad Ellis, PhD, Associate Director

Al Baldwin, PhD, Associate Director,Basic Research

Lisa A. Carey, MD, Associate Director,Clinical Research

Anne Menkens, PhD, AssistantDirector

Andrew Olshan, PhD, AssociateDirector, Population Sciences

Joseph S. Pagano, MD, DirectorEmeritus

Wendy Sarratt, DrPH, AssociateDirector

Thomas Shea, MD, Associate Director,Clinical Outreach

UNC Lineberger Program LeadersEthan Basch, MD, Cancer Preventionand Control

James Bear, PhD, Cancer Cell Biology

Lisa A. Carey, MD, Breast Cancer

Blossom Damania, PhD, GlobalOncology, Virology

Claire Dees, MD, Clinical Research

James Evans, MD, PhD, CancerGenetics

Stephen V. Frye, PhD, MolecularTherapeutics

Neil Hayes, MD, Clinical Research

Gary Johnson, PhD, MolecularTherapeutics

Terry Magnuson, PhD, Genetics

Andrew Olshan, PhD, CancerEpidemiology

Charles M. Perou, PhD, Breast Cancer

Nancy Raab-Traub, PhD, Virology

Kurt Ribisl, PhD, Cancer Prevention & Control

Jon Serody, MD, Immunology

Jenny Ting, PhD, Immunology

Melissa Troester, PhD, CancerPrevention and Control

Yue Xiong, PhD, Cancer Cell Biology

Development & CommunicationsMartin Baucom, Senior ExecutiveDirector of Development &Communications

Eli Jordfald, Senior Director of Major Gifts

Kelly Mansfield, Director ofDevelopment

Betsy Gentry-Bumm, Director of Annual Giving

Aime Mitchell, Director ofDevelopment Operations andStewardship

Jennifer Bowman, Director of Special Events

Bill Schaller, Director ofCommunications & Marketing

Kiecha Berzins, CommunicationsManager

Laura Oleniacz, ScienceCommunications Manager

Claire Nickles, Development &Communications Associate

Clinical Services at N.C. Cancer HospitalLisa A. Carey, MD, Chief of theDivision of Hematology andOncology and Physician in Chief, N.C. Cancer Hospital

David Ollila, MD, Associate Physicianin Chief, N.C. Cancer Hospital

Matt Milowsky, MD, Clinic MedicalDirector, N.C. Cancer Hospital

Marlene Ri!in, RN, Senior VicePresident for Women's and Children'sand Oncology Service

Ian Buchanan, MD, Associate VicePresident for UNC Health Care’sOncology Service Line

Meghan McCann, RN, MSN, NE-BC,Director Oncology Services

FEATURES

INSIDE

Fox fights bone marrowcancer and winsSuperior Court Judge Carl Fox isback on the bench after a cordblood transplant saved his life.

8 16

26 36

The Williams major giftadvances cancer research“We have faith scientists willunlock mysteries behind thisdisease.”

Clinical trials lead to new treatmentsAmy Charney didn’t let breastcancer stop her from reachingthe finish line.

Opening up the lines of communicationBasch lab receives $5.45 million to study patient-reportedoutcomes.

5 Director’s Message 6 Section One: Invest in People to Find a Cure14 Section Two: Venture to Seek Scientific Solutions 24 Section Three: Build Clinical Excellence –

Research and Care to Advance Hope 34 Section Four: Unite Across Population Sciences

to Beat Cancer 44 Major Gifts and Pledges46 Memorial Tributes 48 Honor Roll Donors 52 The Berryhill Society 53 Our Comunity

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“When I grow up, I want to bean astronaut, an oncologist,and an artist. But right now I’m working as a secret agent!”

Charlotte Brinn6 years oldacute lymphoblastic leukemia

CAMPUS BOX 7295CHAPEL HILL, NC 27599-7295

Produced by UNC Lineberger Development & CommunicationsPlease direct comments to 919-966-7834 or email [email protected].

Editors: Kiecha Berzins, APR, Communications ManagerBill Schaller, Director, Communications & MarketingDesign: Leesa Brinkley

Non Profit OrgUS PostagePAIDChapel Hill, NCPermit No. 71

UNC LINEBERGER COMPREHENSIVE CANCER CENTER!"#$ % !"#& DONOR HONOR ROLL

BEAT CANCER.

INVEST IN PEOPLE. SEEK SCIENTIFIC SOLUTIONS.

BUILD CLINICAL EXCELLENCE.


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