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Supplementary Material Design, synthesis, and identification of a novel napthalamide- isoselenocyanate compound NISC-6 as a dual Topoisomerase-IIα and Akt pathway inhibitor, and evaluation of its anti- melanoma activity Deepkamal N. Karelia 1 , Ugir Hossain Sk 2 , Parvesh Singh 3 , A. S. Prakasha Gowda 4 , Manoj K. Pandey 1,5 , Srinivasa R. Ramisetti 1 , Shantu Amin 1 , and Arun K. Sharma 1,* 1 Department of Pharmacology; Penn State Cancer Institute, CH72; 4 Department of Biochemistry and Molecular Biology, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, USA. 2 CSIR-Institute of Himalayan Bioresource Technology, Palampur, HP, India 3 School of Chemistry and Physics, University of Kwa-Zulu Natal (UKZN), Westville campus, Durban 4000, South Africa 5 Department of Biomedical Sciences, Cooper Medical School of Rowan University, 401 S Broadway, Camden, NJ 08103 (current address) S. No. Description Page No. 1 NMR spectral data for compounds 3a, 3b, 3c & 3d S2-S9 S1
