Arterial Input Function Derived From Pair-wise Correlations Between PET Image Voxels

Supplementary figures

Martin Schain, Simon Benjaminsson, Katarina Varnäs, Anton Forsberg, Christer Halldin, Anders Lansner, Lars Farde, and Andrea Varrone.

Supplementary figure 1 3D-rendered summation PET image of one subject measured with [11C]flumazenil. Gray box indicates the image subset used in the PWC algorithm

Supplementary figure 2. Scatter plot between VT estimated with IDIF and MIF in each ROI for a: [11C]flumazenil, and b: [11C]AZ10419369. The linear regression analysis data are reported in Table 2. Solid black line represents identity between the methods.

Supplementary figure 3. Voxels correlating with blood voxels a. as segmented from MRI, and b. 10 hottest pixels per plane on a summation image of the first four frames, for one subject measured with [11C]flumazenil. Voxel overlap = 79.5% between the two methods.