ASMS 2015

TP 137

Q-TOF MS: Powerful Tool for Demystifying Traditional Chinese Medicine Zhengxiang Zhang, Tao Bo; Agilent Technologies Company Limited, Beijing, China

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Q-TOF MS: Powerful Tool for Demystifying Traditional Chinese Medicine

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More importantly, TCM mainly focuses on promoting health andand relatively inexpensive.

For Research Use Only. Not for use in diagnostic procedures.

Q-TOF MS: Powerful Tool for Demystifying Traditional Chinese Medicine

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discovery, forensic toxicology research, manufacturing process

for screening food related raw materials and end products. The same qualitative and quantitative strategy can be utilized for TCM analysis as shown in Fig. 2. DIA modes like All Ions MS/MS, MSE, MS/MSALL with SWATH, and All-ion Fragmentation are preferred choices for data acquisition with improved efficiency. Dedicated personal compound database and library (PCDL) including accurate mass, high resolution MS/MS spectra, and chromatographic retention information enable high throughput straightforward process from screeing to quantitation.

For Research Use Only. Not for use in diagnostic procedures.

Q-TOF MS: Powerful Tool for Demystifying Traditional Chinese Medicine

ASMS 2015 Page 4

For Research Use Only. Not for use in diagnostic procedures.