Proximo TM Hi-C Genome Scaffolding ASSEMBLE Haplotype-Resolved, Chromosome-Scale Platinum Genomes The Proximo™ Genome Scaffolding platform employs cost-effective proximity- ligation data made by in vivo Hi-C to generate high-quality reference genome assemblies, detect structural variation, and phase haplotypes for virtually any genome. Boost your genomic research with new insights captured by Hi-C and bring this technology into your lab with our industry-leading kits and bioinformatic services. KEY FEATURES • Scaffold chromosome-scale genome assemblies using Hi-C data • Fully-phase haplotypes by combining Hi-C data and long-reads • No high-molecular weight DNA extractions or DNA shearing required • Dual-unique indexed Illumina library prep included • Industry-leading bioinformatic services and scientific support For Research Purposes Only. Not for Clinical or Diagnostic Use
The Proximo™ Genome Scaffolding platform employs cost-effective proximity-ligation data made by in vivo Hi-C to generate high-quality reference genome assemblies, detect structural variation, and phase haplotypes for virtually any genome. Boost your genomic research with new insights captured by Hi-C and bring this technology into your lab with our industry-leading kits and bioinformatic services.
KEY FEATURES
• Scaffold chromosome-scale genome assemblies using Hi-C data• Fully-phase haplotypes by combining Hi-C data and long-reads• No high-molecular weight DNA extractions or DNA shearing required• Dual-unique indexed Illumina library prep included • Industry-leading bioinformatic services and scientific support
For Research Purposes Only. Not for Clinical or Diagnostic Use
Proximo™: How it works
Chromosome-scale scaffolding for any genomeTransform your draft assemblies into genomes in one simple step. The most published Hi-C scaffolding method, Proximo dependably yields high-quality end-to-end chromosome scaffolds from diverse species and sample types.
1: Bickhart et al.,Nature Genetics, 2017; 2: Pennisi., Science, Vol. 357, Issue 6346, pp. 10-11 3: Peichel et al., Journal of Heredity, 2017; 4: Maughan et al., BMC Biology, 2017; 5:Burton et al., Nature Biotechnology, 2013; 6: Wallburg et al., BMC Genomics, 2019; 7:Lehmann et al., BioRxiv, 2018; 8: VanBuren et al., Giga Science, 2018; 9: Fallon et al., BioRxiv,2018. More publications: phasegenomics.com
Phase and detect structural variationHi-C captures both short-range and long-range genomic contiguity. Hi-C signal increases as the genomic distance between any two loci across the genome decreases, FALCON-Phase uses this information to phase genomes and ProximoSV detects complex rearrangements, including balanced translocations, chromothripsis, and copy number changes across the entire genome. Collect SNV, CNV, SV, and phase data from a single library prep.
For Research Purposes Only. Not for Clinical or Diagnostic Use
Proximo™: What it can do for you
Kits and Services
Our Services
Complete Sample-to-Analysis Solution
• Everything needed for two sample preps, starting from intact cells
• 3 hours hands-on time • dual-unique indexed
Illumina library prep included in the kit
Take advantage of our expertise
ProxiMeta™ Metagenome Deconvolution• Go beyond 16S and binning techniques to obtain complete genomes directly from a mixed samples
ProximoSV™• Identify large-scale structural variation and determine epigenetic changes using Hi-C data.
FALCON–Phase™• Integrates PacBio and Nanopore long-read assemblies with Hi-C data to generate phased, diploid,
genome assemblies.
Accelerate your metagenomics research with our user-friendly sample prep kits and Proximo Genome Scaffolding software. The kit yields a dual-indexed proximity ligation library, to be sequenced on an Illumina® sequencer.
Customized Kits for Any Sample Type
Not an expert in sample preparation? Let us do the hard work with our services, which includes Hi-C library preparation, sequencing, and analysis. Looking to expand your genomics research? Contact us for more genomic services listed below.
Unless otherwise stated, data on file.For Research Use Only. Not for use in diagnostic procedures.PROXIMETA, PROXIMO and FALCON-PHASE are trademarks of Phase Genomics, Inc. All other product names and trademarks are the property of their respective owners.
