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Autoimmune and Arthritis Upload

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    JBorrero 10/10

    MusculoskeletalStressors

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    Arthritis

    Degenerative Joint Diseases Arthritis= joint inflammation.

    Arthralgia= joint painDifferent types of arthritis:

    Osteoarthritis

    Rheumatoi arthritis!outy arthritis

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    Osteoarthritis

    "ost #ommon form of arthritis$ noninflammatory$nonsystemic isease

    One or many joints un ergo egenerative anprogressive #hanges$ mainly %t. &earing joints.'tiffness$ ten erness$ #repitus an enlargement

    evelop.Deformity$ in#omplete islo#ation an synovialeffusion may eventually o##ur.(reatment: rest$ heat$ i#e$ anti inflammatory rugs$

    e#rease %t. if in i#ate $ inje#ta&le #orti#osteroi s$surgery.

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    Osteoarthritis- Risk Factors

    AgeDe#rease mus#le strength

    O&esity)ossi&le geneti# ris*+arly in isease pro#ess$ OA is iffi#ult to ,

    from RA-, of (rauma to joint

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    OA- Signs and Symptoms

    Joint pain and stiffness that resolves withrest or inactivity

    )ain %ith joint palpation or ROJ"repitus in one or more joints+nlarge joints

    -e&er en s no es enlarge at istal ) jointsBou#har s no es lo#ate at pro,imal )

    joints

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    Osteoarthritis- !

    )harma#otherapy3 tylenol$ 4'A D'$ A'A$ o,35inhi&itors

    ntra3arti#ular inje#tions of #orti#osteroi s!lu#osamine3 a#ts as a lu&ri#ant an sho#*a&sor&ing flui in joint$ helps re&uil #artilageBalan#e rest %ith a#tivity

    6se &ra#ing or splints Apply thermal therapies Arthroplasty3 joint repla#ement #an relieve pain anrestore loss of fun#tion for patients %ith a van#e

    isease.

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    Auto-"mmune #isease

    nflammatory an immune response are normallyhelpfulB6( these responses #an fail to re#ogni7e self #ellsan atta#* normal &o y tissues.

    alle an auto3immune responsean severly amage #ells$ tissues an organs

    +!. RA$ '2+$ )rogressive systemi# s#lerosis$#onne#tive tissue isor ers an other organ spe#ifi#isor ers

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    Rheumatoid Arthritis

    hroni#$ systemi#$ progressive inflammatoryisease of the synovial tissue$ $ilateral%

    involving numerous joints.'ynovitis3%arm$ re $ s%ollen joints resultingfrom a##umulation of flui an inflammatory#ells.

    lassifie as autoimmune pro#ess+,a#er&ations an remissionsan #ause severe eformities that restri#t

    fun#tion

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    RA- Risk Factors

    8emale gen er Age 50390 years

    !eneti# pre isposition+pstein Barr virus'tress

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    Rheumatoid Arthritis- #!

    Rheumatoi 8a#tor anti&o y3 -igh titers#orrelate %ith severe isease$ 0; pts.

    Antinu#lear Anti&o y 0; pts.

    +'R: +levate $ mo erate to severe elevation Artho#entesis3 synovial flui aspirate &ynee le

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    RA & Signs and Symptoms

    Joints3 &ilateral an symmetri# stiffness$ ten erness$s%elling an temp. #hanges in joint.)ain at rest an %ith movement)ulses3 #he#* peripheral pulses$ use oppler ifne#essary$ #he#* #apillary refill.+ ema3 o&serve$ report an re#or amt. an lo#ationof e ema.RO"$ mus#le strength$ mo&ility$ atrophy

    Anore,ia$ %eight loss8ever3 generally lo% gra e

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    RA- Sign and Symptoms

    1. 8atigue3 unusual fatigue$ generali7e %ea*ness5. Morning stiffness lasting longer than '( minutes

    after rising% su$sides with activity .?. Re $ %arm$ s%ollen$ painful joints@. 'ystemi# ' '9. )ain3 at rest an %ith movement

    hat shoul %e monitorC

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    Rheumatoid Arthritis- !

    Rest$ uring ay3 e#rease %t. &earing stress.RO"3 maintain joint fun#tion$ e,er#ise %ater.

    "e i#ation3 analgesi# an anti3inflammatory

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    )ursing "nterventions

    Assist %ith/en#ourage physi#al a#tivity)rovi e a safe environment

    6tili7e progressive mus#le rela,ationRefer to support groups+motional support

    A" Assistive evi#es-ome #are nee s

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    +outy ArthritisEery painful joint inflammation$ s%ollen an re ene)rimary3 n&orn error of uri# a#i meta&olism3 in#reases pro u#tionan interferes %ith e,#retion of uri# a#i'e#on ary3 -yperuri#emia #ause &y another isease+,#ess uri# a#i #onverte to so ium urate #rystals anpre#ipitate from &loo an &e#ome eposite in joints3 tophi or in*i neys$ renal #al#uli(reatment:"e s3 #ol#hi#ine$ 4'A D'$ n o#in

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    Systemic ,upusrythematosus

    '2+3 hroni# nflammatory isease affe#ting manysystems.

    omen &et%een 1 3@0$ &la#*F%hite$ #hil &earing

    years Autoimmune pro#ess3 anti&o ies rea#t %ith D4A$immune #omple,es form3 amage organs an &loovessels.

    n#lu es: vas#ulitisG renal involvementG lesions of s*inan nervous system$ photosensitivity$ oral ul#ersnitial manifestation3 arthritis$ $utterfly rash $

    %ea*ness$ fatigue$ %t. loss

    'ymptoms an t,. epen on systems involve .

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    Systemic ,upusrythematosus

    )athologi# #hanges3Autoimmune pro#ess1. Eas#ulitis in arterioles an small arteries5. !ranulomatous gro%ths on heart valves3 non &a#terial

    en o#ar itis.?. 8i&rosis of the spleen$ lymph no e a enopathy@. (hi#*ening of the &asement mem&rane of glomerular

    #apillaries.9. >0; s%elling an inflammatory infiltrates of synovial

    mem&rane.H. Renal3 2upus nephritisI. )leural effusion or )4

    . Raynau s phenomenon3 a&out 19; #ases>. 4euro3 psy#hosis$ paresis$ migraines$ an sei7ures

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    S, #!

    A4A3 hallmar* test$ in > ; pts."e i#ations3

    4'A D'

    Antimalarial me s3 hy ro,y#hloroKuine

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    Systemic ,upus- ducation

    +n#ourage to avoi un ue emotional/ physi#alstress an to get enough rest Alternate e,er#ise planne rest perio s.(ea#h ho% to re#ogni7e the symptoms of a flare(ea#h ho% to prevent an re#ogni7e infe#tion

    Avoi sunlight$ use suns#reen+at a %ell &alan#e iet$vitamins an iron.+sta&lish short term goals(ea#h re: me s."e s avoi 3 )ronestyl$ -y rala7ine.


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