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Basic Concept of Basic Science for Nursing

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    Bioscience for Nursing II:An introduction

    Basic Science and Fundamental of Nursing Group

    Faculty of Nursing Universitas Indonesia

    2011

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    Visi Prodi S1 Ilmu Keperawatan

    Tahun 2013 menjadi pusat unggulan

    pendidikan keperawatan professionalberbasis riset yang unggul dalam

    IPTEK keperawatan yang peka budaya

    sesuai kebutuhan kesehatanmasyarakat nasional dan internasional.

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    Misi Prodi S1 Kep

    1. Menyiapkan peserta didik menjadi sarjanakeperawatan yang mampu bersaing secaranasionaldan internasional;

    2. Menggunakan hasil-hasil riset dalamkegiatan pendidikan keperawatan yang pekabudaya untuk kesejahteraan masyarakat;

    3. Menerapkan evidence-based practicedalam bidang keperawatan.

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    What we will cover today

    To learn about the discipline of

    Bioscience for nursing

    To learn how Bioscience applies to

    clinical practice

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    Why should we study bioscience?The goal is also clearly to be a professional nurse:

    - think rationally and scientifically

    - bioscience (including pathology) is a

    foundation for nursing professional science

    - holistic care; illness is as a result of

    abnormalities on biological (on cells,

    tissue, & organ), psychological, social, &

    spiritual factors.

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    Component of Bioscience forNursing II

    PathologyMicrobiology & Parasitology

    Pharmacology

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    PATHOLOGY

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    What is Pathology?

    Root Word:

    Path(pathos) means suffering, disease

    Suffix:

    logy(logos) means study, science

    The study of disease

    The study of the functional, biochemical, and

    morphological alteration in cells, tissue, and organsthat underlie disease

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    DEFINITIONS & TERMINOLOGY

    Disease:1. a disorder of structure or function, especially that

    produces specific clinical signs

    2. any deviation from, or interruption of, the normalstructure or function of organ or one system of thebody; which may be clinical (characteristic set ofsymptoms & signs) or sub clinical and whose

    etiology, pathogenesis and prognosis may be knowor unknown

    (http://people.upei.ca/hanna/)

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    DEFINITIONS & TERMINOLOGY(2)

    Symptom:

    any indication of disease perceived

    by the patient. Applicable to animal?Sign:

    observed abnormality of structure or

    function

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    The key point of nursingscience

    To prevent

    To diagnose

    To care

    ( Control)

    Diseases

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    The contents of pathologyv Etiology (the causes )

    v Pathogenesis (mechanisms frominitiation to disease development)

    v pathologic changes (structural &functional, biochemistry abnormalitiesthat are characteristic of the disease

    v clinical significance (nature of the

    morphologic changes & theirdistribution in organs/tissues influencenormal function and determine theclinical signs, course, and prognosis ofthe disease)

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    1. Causes of disease

    Identification of the causative factors that initiate thedisease process.

    1). Genetic factors2). Environmental factors

    Although the causes of disease are divided into above two main

    groups, but both groups are interlaced in most diseases.

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    2. Pathogenesis

    Defining the disease mechanisms.How do the causative factors change normal physiologicalprocesses?

    How do these functional changes cause changes in tissuestructure?

    Most are still investigating. Some of them should be known,for instance:

    Thrombosis

    Myocardial infarction

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    3. Pathologic changesWhat are the specific changes in function and structure that characterize each disease?

    Level A.Naked eye level:

    gross changes in diseased organs.

    Level B.Light microscopic level:

    in histological and cytological level.

    Level C.Electron-microscopic(EM) level:

    in the ultrastructure (cellular organelles).

    Level D.Molecular level:

    inspect aberrant in DNA, RNA, and protein.

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    4. Manifestations

    The functional consequences of the morphologic changes.

    Can these changes from normal be detected by clinical tests such asexamination of the blood or urine?

    Can the structural changes be identified by techniques such as x-ray,ultrasound, nuclear medicine, or examination of tissue samples (biopsies)?

    What clinical signs and symptoms are produced by the disease process?

    How does the disease process produce these signs and symptoms?

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    5. Progress and sequels

    Progress

    simple intricate

    short-term long-term

    Sequels

    healing

    un-healing: delay & complications

    spread even death

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    CLINICAL TASKS

    In clinical practice, the objective of the study of diseasehas several purposes:

    Diagnosis: to determine the nature of the disease processand its causation, i.e. to establish a diagnosis if possible.

    Intervention: To monitor the extent and progress of thedisease and provide an indication of prognosis. Caring ofthe patient's problem is very often based on thisinformation.

    Prevention: To use knowledge of the mechanisms ofdisease to prevent disease in individuals or populations ofpeople or animals.

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    The classification ofpathology

    General pathology: the study of basic reactions ofcells and tissues to abnormal stimuli that underliediseases

    i.e. injury, repair, inflammation, neoplasia.

    Systemic pathology: the study of the specificresponse of specialized organs and tissues to more orless well defined stimuli

    i.e. cardiovascular diseases, respiratory diseases,endocrine diseases, etc.

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    Diseases-->Pathology--> Nursing

    Practice

    Variations ofstructurefunctionoutsidenormal range

    (1) Causes (etiology)(2) Mechanisms (Pathogenesis)(3) Pathological changes(4) Manifestations(5) Progress and sequels

    Diagnosing

    Caring/intervention

    Preventing

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    The location and importance ofbioscience in nursing education

    Pathology is a bridge between basic science andclinical nursing. All of the nursing students haveto stride over the bridge!

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    Selamat Belajar!!


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