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Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical Physicist, Nuclear Medicine Department of Radiology Section of Nuclear Medicine 201 East Huron Street Galter Pavillion 8-118 Chicago, Illinois 60611 USA Tel: 312-926-3138 email:[email protected]
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Page 1: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Fundamentals of Radiation Physics

Vanessa L. Gates, M.S., DABR, DABSNM

Medical Physicist, Nuclear Medicine

Department of Radiology

Section of Nuclear Medicine

201 East Huron Street

Galter Pavillion 8-118

Chicago, Illinois 60611 USA

Tel: 312-926-3138

email:[email protected]

Page 2: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Objectives

Radioactive Decay Describe difference between gamma radiation and particulate

radiation (beta particles)

Production of Radionuclides

Interaction of photons and particles with matter

(tissue, lead, acrylic and air)

Page 3: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical
Page 4: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Radioactive Decay

Page 5: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Gamma Decay

- Change in Nuclear Energy

Nuclide has excessive energy

Becomes stable by releasing

energy in form of gamma ray

Gamma ray has discrete

energy, no mass, and no

charge

Nuclide does not change

Page 6: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Beta Decay

- Change in Nuclear Energy

Nuclide has excessive neutrons

Neutron converts to proton +

beta particle + anti-neutrino

Energy released as kinetic

energy of beta and anti-neutrino

Beta is similar to an electron

Anti-neutrino has very little

mass and is neutral

Nuclide changes due to addition

of proton

Page 7: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Radioactivity

Rate of transformation of radionuclides

through the emission of energy in the form of a

particle or a photon

1 Bq = 1 transformation per second

Y-90 Zr-90 + b + n

Page 8: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Radionuclide decay

0.00

2.00

4.00

6.00

8.00

10.00

12.00

14.00

16.00

18.00

20.00

Sunday Monday Tuesday Wednesday Thursday Friday

3 GBq

5 GBq

7GBq

10 GBq

15 GBq

20 GBq

Half-Life = T1/2

Page 9: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Production Methods

Page 10: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Reactor - Adding Neutrons

Y-89(n,) Y-90

Resource: http://www.nuclearfaq.ca/maple_core_cerenkov.jpg

Page 11: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Accelerators – Adding Protons

Ne-20(d,α) F-18

F-18Ne-20 + p +p

n

np p

Page 12: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Generator - Decay

Mo-99→Tc-99m

Resource: www.bnl.gov/bnlweb/pubaf/pr/1998/bnlpr101698.html

Tc-99m +b+

nMo-99

Page 13: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Interaction of photons and

particles with matter

Page 14: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Source: course_x_-_arls_-_radiation_exposure_principles_-_alvarez_joe.pdf

Page 15: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Interaction of photons with matter

Page 16: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Electromagnetic Waves

Interaction with Matter

Type of Interaction Photons

Rayleigh Scattering

Photoelectric Absorption

Compton

Absorption/Scatter

Pair Production

Photonuclear Activation

Radio

Microwave

Infrared

Light

UV

X-Rays

Gamma Rays

Page 17: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Photo-electric Effect

All of gamma energy is given to orbiting electron in the material.

Page 18: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Compton Scattering

Fraction of gamma energy is given to orbiting electron in the material.

Page 19: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Absorption of X-ray and gamma

Page 20: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Gamma Attenuation/Absorption

Energy of gamma

Composition of material

HVL – Half Value Layer

X - Thickness of Absorber

Page 21: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Interaction particles with matter

Page 22: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Example of Beta EmittersLight Source –

Tritium gas ( H3 ) Food - Bananas

Page 23: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Beta Particle Kinetic EnergyMaximum Energy ~ 2.28 MeV

Average Energy ~ 0.9367 MeV

b + n 2.28 MeV

http://www.doseinfo-radar.com/BetaSpec.zip

Page 24: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Interaction of charged particles• Coulombic Interaction

• mechanical

• knocks electron off its orbit

• Bremsstrahlung Production

• Radiative Loss

• Braking Radiation

Page 25: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Bremsstrahlung Production -

Radiative Loss

Percentage of Radiative Loss ~ (Zeff*Emax)/3000 * (100%)

Water, Tissue, or Plastic ~ 0.6%

Lead (Pb) ~ 6.2%

Page 26: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Bremsstrahlung vs. Gamma

Radiation

Gamma Bremsstrahlung

Discrete Energy

dependent on

radionuclide

Spectrum of Energy

dependent on beta

particle energy and

interaction with nucleus

http://www.search.com/reference/Neutron_activation_analysis

Page 27: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Coulombic Interaction-

Collisional Loss

Water, Tissue, or Plastic ~ 99.4%

Lead (Pb) ~ 93.8%

Page 28: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Beta Particle Range Varies

Extrapolated Range

Background due to Bremsstrahlung Penetration

Page 29: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Particle Maximum Range

Medium Y-90 Maximum Range in mm

Air 10375

Plexiglass 9.8

Water 11.3

Glass, Pyrex 6.0

Lead 1.63

Tissue, Soft 11.4

Bone, Compact 6.6

Bone Cortical 6.8

The above data was generated using e-star software from the NIST website.

Page 30: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Y-90 Radiat ion Dose Rate

0

0.01

0.02

0.03

0.04

0.05

0.06

0.07

0.08

0.09

0.1

0 0.2 0.4 0.6 0.8 1

Distance (cm)

Dose

Rate

(cG

y/s

)

Effective Dose Range Depends on

Radiation Absorbed Dose Rate – cGy/s

Page 31: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Radiation Measurement

Terminology

Page 32: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Radiation Exposure

Refers to the amount of ionization produced in

air by x- or -rays only

Σ charges (either + or -) produced in air

when all the electrons liberated by photons

in a mass of air are stopped.

Roentgen (R) = 2.58 x 10 -4 C/kg

Page 33: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Radiation Absorbed Dose

Amount of ionizing energy (J) deposited in a

kg of material such as liver tissue

1 Gy = 1 J/kg

In air...

1 C ~ 34 J

1 R = 2.58 x 10 -4 C/kg X 34 J/C

= 8.8 x 10 -3 J/kg

= 8.8 mGy

1 Gy = 100 rad

Page 34: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Dose vs Dosage

Dose generally refers to the radiation absorbed

dose and should have units of Gray (Gy)

Dosage generally refers to the quantity of

material being administered and should have

units such as

Radioactivity (Bq)

Volume of the microspheres suspended (ml)

Mass of the microspheres administered (mg)

Vial labeled quantity such as the activity at the time

of calibration (i.e. 3 GBq vial size)

Page 35: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical
Page 36: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q1. Dosage in radioembolization

is defined as

a) the radiation absorbed dose and should have

units of Gray (Gy)

b) the quantity of material being administered and

should have units of radioactivity (Bq)

c) the quantity of material being administered and

should have units of volume (ml) or mass (mg)

d) Both b and c

Page 37: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q1. Dosage in radioembolization

is defined as

a) the radiation absorbed dose and should have

units of Gray (Gy)

b) the quantity of material being administered and

should have units of radioactivity (Bq)

c) the quantity of material being administered and

should have units of volume (ml) or mass (mg)

d) Both b and c

Page 38: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q2. Y-90 is produced by

a) Adding a proton to Sr-90 in a cyclotron

b) Adding a neutron to Y-89 in a reactor

c) Decaying Sr-90 using an Al generator

d) None of the above

Page 39: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q2. Y-90 is produced by

a) Adding a proton to Sr-90 in a cyclotron

b) Adding a neutron to Y-89 in a reactor

c) Decaying Sr-90 using an Al generator

d) None of the above

Page 40: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q3. Which of the following is true

of Bremsstrahlung transmission

through tissue or water?

a) The transmission varies exponentially with the

thickness of tissue.

b) The transmission varies linearly with the

thickness of tissue.

c) Bremsstrahlung cannot be transmitted through

tissue.

d) None of the above

Page 41: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q3. Which of the following is true

of Bremsstrahlung transmission

through tissue or water?

a) The transmission varies exponentially with the

thickness of tissue.

b) The transmission varies linearly with the

thickness of tissue.

c) Bremsstrahlung cannot be transmitted through

tissue.

d) None of the above

Page 42: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q4. Which of the following is true

for beta particles in tissue or

water?

a) The HVL is equal to the extrapolated range.

b) The primary interaction involves the transfer of

beta particle energy to an orbiting electron.

c) Gamma rays are produced.

d) None of the above

Page 43: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q4. Which of the following is true

for beta particles in tissue or

water?

a) The HVL is equal to the extrapolated range.

b) The primary interaction involves the transfer of

beta particle energy to an orbiting electron.

c) Gamma rays are produced.

d) None of the above

Page 44: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q5. Beta particles may undergo

Bremsstrahlung production in acrylic

shielding; therefore the acrylic shielding

should also be shielded with lead to

protect the user from Bremsstrahlung.

(True or False)a) True

b) False

Page 45: Basic Principles of Radiation Physicsdvl.sirweb.org/media/SIR11Y90_1/SIR11Y90-03/SIR11Y90-03-01/SIR11Y...Fundamentals of Radiation Physics Vanessa L. Gates, M.S., DABR, DABSNM Medical

Q5. Beta particles may undergo

Bremsstrahlung production in acrylic

shielding; therefore the acrylic shielding

should also be shielded with lead to

protect the user from Bremsstrahlung.

(True or False)a) True

b) False


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