BCS BiologicsProduct OverviewsGlen CroweTechnical Sales Specialist

Why Biologics?

• Resistance Management Benefits

• Residue management benefits

• Enhanced yield and crop quality

• Labor management benefits

• Enhanced control with conventional chemistry

Understanding natural products chemistry

Iturin

Agrastatin

Surfactin

Macrolactin Bacilysin

IAA

2,3-butanediol

Difficidin

A.I.=QST713

Serenade Performance Drivers - Foliar

Foliar Products

Anti-fungal lipopeptide chemistry

XXX

Chemistry deliveredin the jug

chemistryAnti-bacterial

chemistry XXX

Chemistry-mediated induced response XXX

Physical barrier to pests X

Cell membrane is a sandwich with water soluble outside and greasy middle

Lipopeptides are small protein rings with a lipid (fat) attached

Mode of action of Lipopeptidechemistry

with a lipid (fat) attachedOne end is negatively charged, the other is “greasy”

Lipopeptides insert into membrane and create small holes

Lipopeptides Disrupt Cell Membranes

48hpi

Untreated control 48 hpi with Blumeria graminis Inoculation of B. graminis 12h after application with Serenade®

Spores in contact with the Serenade® film do not germinateGermination and massive proliferation of

B. Graminis after 48H.

BASF pictures

BASF BASF

Foliar Products – Next Generation

Concentrated wettable powder26.2% ai

1.31 X 1010 CFU/g

shelf stable for 5 years

widely tank mix and rotation compatible

Improvements over previous formulations:• New formulation makes anti-fungal and anti-bacterial chemistry more bio-

available• Improved spectrum and levels of control• Reduced dustiness and deposit

Serenade Performance Drivers - Soil

Foliar Products Soil Products

Chemistry delivered in the jug

Anti-fungal lipopeptide chemistry XXX Contact control of

pathogens in a treated volume of soilAnti-bacterial

chemistry XXX

Chemistry-mediated induced response XXX XXX

Physical barrier to pests X XXX

Chemistry resulting from root colonization

Chemistries drivingstress resistance XXX

Chemistries impacting nutrient solubilization XXX

Chemistries regulating efficiency of plant processes like photosynthesis

XXX

As SERENADE SOIL colonizes the root, it builds a dense barrier protecting it

Unt

reat

ed w

ater

co

ntro

l Untreated roots stand “naked” to potential attack by soil diseases

Unt

reat

ed w

ater

SE

REN

ADE

SOIL

Digital Microscopy Fluorescence Microscopy

SERENADE SOIL builds a dense barrier around the root, including the tip, and grows with the plant as the plant grows

© AgraQuest

SERENADE SOIL protection grows as the roots grow

SERENADE SOIL treats the soil area, but in addition it colonizes the roots, developing a protective armor that protects roots from soil diseases – even at the tip.

As the root grows, SERENADE SOIL grows with it providing protection against pathogens beyond the treated soil area

© AgraQuest

Crop Rhi

zoct

onia

Pyth

ium

Fusa

rium

Vert

icill

ium

Phyt

opht

hora

Scle

rotin

ia

Stre

ptom

yces

sc

abie

s

Scle

rotiu

mro

lfsii

Phom

a

Like

ly

Expa

nsio

n

Cucurbits l l l l l

Fruiting Vegetables l l l l l l

Effects of Serenade SOIL are broad-spectrum

Legumes l l l l l l

Peanuts l l l l l l l Cylindrocladium black rot

Root and tubers l l l l l l Storage disease claims

Cereals l l l l l

Brassicas l p

Leafy Vegetables l l l

Citrus l l

Strawberries p l

Bulb vegetables p p p l

l Proven Use p Future Expansion

SONATA Fungicide

Foliar fungicide for the management of Rust, Mildew, Blight, Alternaria and Cercospora

GROWER BENEFITS • MRL exemption

Based on the active ingredient Bacillus pumilus QST 2808

• Short REI (4 hours) and PHI (0 days)• Beneficials safety • Novel Mode of Action• Can be applied through Chemigation and Aerial application• Compatible with wide range of other pesticides and fertilizers• Contact disease control, growth promotion, induced resistance and yield enhancement• Compatibility with Strobilurins at low rates. • Aqueous formulation with 2 year storage stability

SONATA - Modes of Action

1. Antifungal amino sugars present in SONATA compete with the enzymethat uses glucose to build new pathogen cell walls.

Results in:- Inhibition of septum formation- Inhibition of cell wall formation

2. Activate the plant's defenses

3. Promotes plant growth

- Inhibition of cell wall formation- Destruction of cell integrity- Cell death

SONATA - Kills Germinating Spores

Water SONATA1%

Morphological changes in early growth of Colletotrichum spores (anthracnose) in liquid culture.