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US Guided Fluid Resuscitation Michiel J. van Veelen, Emergency Physician, DTM&H Bedside Ultrasound
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US Guided Fluid ResuscitationMichiel J. van Veelen, Emergency Physician, DTM&H

Bedside Ultrasound

Leerdoelen

Ultrasound Guided Fluids

Outline

• Shock and Fluid Resuscitation in ICU

• Ultrasound in Shock

• Ultrasound Guided Fluid Resuscitation

• Other Ultrasound applications in ICU

Leerdoelen

Shock in ICU

“Cellular and tissue hypoxia due to reduced oxygendelivery and/or increased oxygen consumption or inadequate oxygen utilization”

Ultrasound Guided Fluids

Leerdoelen

Fluid Resuscitation in ICU

Ultrasound Guided Fluids

Leerdoelen

Fluid Resuscitation in ICU

Inadequate fluid resuscitation results in tissue hypoperfusion and worsening end-organ

dysfunction

vs.

Overresuscitation leading to a positive fluid balanceis associated with worsened mortality

Ultrasound Guided Fluids

Leerdoelen

Shock in ICU

Ultrasound Guided Fluids

?

Leerdoelen

Fluid responsiveness

• Non-invasive

hemodynamics

• Physical examination

• Invasive hemodynamics;

PAC, CVP, PPV, SVV…

• Passive leg raise test

• Fluid bolus

Ultrasound Guided Fluids

Leerdoelen

Fluid responsiveness

Fluid responderCardiac output (CO) increases by 10-15% in response

to a fluid bolus

Non-responderDecreased CO or minimal increase

Ultrasound Guided Fluids

Leerdoelen

Several US Shock protocols

• Goal Directed Echocardiography (GDE)

• Rapid Ultrasound in Shock (RUSH)

• Rapid Assessment by Cardiac Echo (RACE)

Ultrasound Guided Fluids

Leerdoelen

Pros:

• Effective, noninvasive, rapid and accurately assesshemodynamically unstable patients at the bedside 1-3

• Differentiate between hypovolemic, cardiogenic, obstructive, and distributive shock 2-6

• Serial exams for monitoring 4,5

Ultrasound Guided Fluids

Leerdoelen

Easy?

RUSH exam2

Ultrasound Guided Fluids

Leerdoelen

Alternative?

Just 2 views:

- Inferior Vena Cava- The Lungs

1

2

Ultrasound Guided Fluids

Leerdoelen

C. Lee, P. Kory, R. Arntfield.

Development of a fluid resuscitation protocol using

inferior vena cava and lung ultrasound

Journal of Critical Care, Volume 33, June 2016

Ultrasound Guided Fluids

Leerdoelen

Systematic review of current literature

Evaluation of Ultrasound guided resuscitation studies using two (2) views:

• Inferior Vena Cava• Lung Ultrasound

Proposal of an easy to use algorithm

Development of a fluid resuscitation protocol using inferior vena cava and lung ultrasound

Ultrasound Guided Fluids

Leerdoelen

Why Inferior Vena Cava

Spontaneous breathingintrathoracic pressure with inspiration draws blood from the vena cava into the heart, leading to collapse

Positive pressure ventilationintrathoracic pressure pushes blood from the heart

into the vena cava, leading to distention of the vessel.

Ultrasound Guided Fluids

Leerdoelen

Interpretation

Static measurement of IVC diameter and variation with spontaneous respiration correlates with central venous pressure (CVP) 3,4

A change in IVC diameter with respiration of 12 -18% is associated with fluid responsiveness in mechanically ventilated patients 4-6

Ultrasound Guided Fluids

Leerdoelen

IVC

Ultrasound Guided Fluids

LUNGS

Why Lung Ultrasound?

Ultrasound Guided Fluids

A B

LUNGS

Ultrasound Guided Fluids

LUNGS

Ultrasound Guided Fluids

Leerdoelen

Ultrasound Guided Fluids

Leerdoelen

IVC

1

Ultrasound Guided Fluids

Leerdoelen

IVC Measure diameter

<1.5cm Underfilled>2.5cm Distended1.5-2.5cm Normal

1

Ultrasound Guided Fluids

LeerdoelenPitfalls

Ultrasound Guided Fluids

IVC Diameter

>2.5cm: Hold Fluids

<1.5cm: FLUIDS

Normal: Step 2

Ultrasound Guided Fluids

Intubated?

Yes: Respiratory variation

No/Triggering: Lung Ultrasound

2A

2B

Ultrasound Guided Fluids

Leerdoelen

IVC

Respiratory variation:[(Dmax − Dmin)/Dmax] × 100% > 12% ?

2A

Ultrasound Guided Fluids

Respiratory variation

>12%: FLUIDS

<12%:Lung Ultrasound 2B

Ultrasound Guided Fluids

Leerdoelen

LUNGS

2B

Ultrasound Guided Fluids

Leerdoelen

LUNGS2B

Ultrasound Guided Fluids

Leerdoelen

A Lines

Fluid Test

B Lines

Hold Fluids

2B

Ultrasound Guided Fluids

Leerdoelen

Ultrasound Guided Fluids

Leerdoelen

Ultrasound in ICU

Other applications in ICU:

Leerdoelen

Hypovolemic Cardiogenic

Distributive Obstructive

?

Ultrasound in ICU

Leerdoelen

Vascular access

Ultrasound in ICU

Leerdoelen

Pneumothorax?

Ultrasound in ICU

Leerdoelen

Infiltrate or Effusion?

Ultrasound in ICU

Leerdoelen

Treatable causes in CPR

Ultrasound in ICU

Leerdoelen

Or termination of CPR

Ultrasound in ICU

Leerdoelen

Free fluid in traumaEctopic Pregnancy

AAABladder

GalbladderKidneys

….

Ultrasound in ICU

Leerdoelen

Take home messages

• US is a reliable, affordable and rapid bedside test to evaluate for fluid responsiveness in the ICU patient in shock

• CAVE: Do not forget the entire clinical picture!

• US is operator dependent and requires practice

• US has many potential applications in ICU

Ultrasound Guided Fluids

Leerdoelen?

Ultrasound Guided Fluids

Leerdoelen

References

1. G.A. Schmidt, S. Koenig, P.H. Mayo: Shock. Ultrasound to guide diagnosis and therapy. Chest. 142 (4):1042-1048 2012

2. P. Perera, T. Mailhot, D. Riley, D. Mandavia: The RUSH exam: Rapid Ultrasound in SHockin the evaluation of the critically ill. Emerg Med Clin North Am. 28 (1):29-56, vii February 2010

3. E. Manno, M. Navarra, L. Faccio, et al.: Deep impact of ultrasound in the intensive care unit: the “ICU-sound” protocol. Anesthesiology. 117 (4):801-809 October 2012

4. A. Dipti, Z. Soucy, A. Surana, S. Chandra. Role of inferior vena cava diameter in assessment of volume status: a meta-analysis. Am J Emerg Med, 30 (8) (2012) [1414–1419.e1]

5. C.Lee, P. Kory, R. Arntfield. Development of a fluid resuscitation protocol using inferior vena cava and lung ultrasound, Journal of Critical Care, Volume 33, June 2016, Page 267

6. D.A. Lichtenstein, G.A. Mezière: Relevance of lung ultrasound in the diagnosis of acute respiratory failure the BLUE protocol. Chest. 134:117-125 2008

Ultrasound Guided Fluids

Leerdoelen

Ultrasound Course

Bedside Ultrasound

Course

What

One-day SA college of EM accredited introduction course provided

by international faculty: E-FAST, DVT, Cardiac, Aorta and IV acces.

Target Audience

Doctors of all specialties interested in improving their bedside

diagnostic skills using US, especially in acute settings

When and where

Friday 16th of June 2017, Faculty of Health Sciences 246, Room

xxx

Costs

1250 Pula, incl. online study material, certificate, food and drinks

Registration

Payment is made at Vote P0129, please mention Ultrasound

course. Deliver receipt to UB teaching Hospital, ground floor, Office

1004. Training is done on first come first serve basis and ONLY

after payment is made.

Questions: [email protected]

Department of Accident &

Emergency

Registration open

16th of June

Full day course

Pre-course material

• E-FAST• DVT• Cardiac and IVC• Aorta• Central Venous Access

Certificate EMSSA

1250 Pula


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