Benzotriazole Amino Acids

Iris Biotech GmbH Waldershofer Str. 49-51 D-95615 Marktredwitz, Germany

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Tel.: +49-9231-9619-73 Fax: +49-9231-9619-99

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Iris BIotech

Î They have proven to be outstandingly useful for the synthesis of primary, secondary, and tertiary amides, of depsipeptides and oligoesters, and in particular of difficult peptide sequences.

Î Chemical ligation and other difficult conjugates can be synthesized with high yield and purity.

Î Benzotriazoles (Bt) are a superior alternative to formerly used NHS (N-hydroxysuccinimide) and Pfp (pentafluorophenol) esters.

Î Benzotriazoles (Bt) have a significant difference to N-hydroxybenzotriazoles (HOBt)! The latter ones are being prepared with potentially explosive HOBt and are rather instable, while Benzotriazole (Bt) compounds are very stable and not hazardous, at all.

Custom Synthesis Service

H2NO

OH

R'

O

O

R''

Synthesis of Sophisticated Benzotriazole Activated Compounds for Conjugation at Client’s Lab

Synthesis of Protein and

Antibody Drug Conjugates

Synthesis of Difficult Peptide Sequences

or Depsipeptides

With our know-how we can carry out custom synthesis of difficult compounds.

f Synthesis and antibacterial evaluation of amino acid–antibiotic conjugates;

Mohamed A. Ibrahim, Siva S. Panda, Antoinette S. Birs, Juan C. Serrano,

Claudio F. Gonzalez, Khalid A. Alamry, Alan R. Katritzky; Bioorganic &

Medicinal Chemistry Letters 2014; 24: 1856-1861.

f N-Acylbenzotriazoles: neutral acylating reagents for the preparation of

primary, secondary, and tertiary amides; Alan R. Katritzky, Hai-Ying He,

Kazuyuki Suzuki; J. Org. Chem. 2000; 65(24): 8210-3.

f Total synthesis of cyclic heptapeptide Rolloamide; Mirna El Khatib, Mohamed

Elagawany, Eray Çalis-kan, Emily Faith Davis, Hassan M. Faidallah, Said A.

El-feky, Alan R. Katritzky; Chem. Commun. 2013; 49: 2631.

f Microwave-Assisted Solid-Phase Peptide Synthesis Utilizing N-Fmoc-Protected

(alpha-aminoacyl)benzotriazoles; Alan R. Katritzky, Niveen M. Khashab,

Megumi Yoshioka, Danniebelle N. Haase, Krista R. Wilson, Jodie V. Johnson,

Alfred Chung, Carrie Haskell-Luevano; Chem. Biol Drug. Des. 2007; 70: 465-

468.

f N-Tfa- and N-Fmoc-(alpha-aminoacyl)benzotriazoles as Chiral C-Acylating

Reagents under Friedel-Crafts Reaction Conditions; Alan R. Katritzky, Rong

Jiang, Kazuyuki Suzuki; J. Org. Chem. 2005; 70: 4993-5000.

f Benzotriazole-Mediated Syntheses of Depsipeptides and Oligoesters; Ilker

Avan, Srinivasa R. Tala, Peter J. Steel, Alan R. Katritzky; J. Org. Chem. 2011; 76:

4884–4893. dx.doi.org/10.1021/jo200174j.

f Chemical Ligation of S-Acylated Cysteine Peptides to Form Native Peptides via

5-, 11-, and 14-Membered Cyclic Transition States; Alan R. Katritzky, Srinivasa

R. Tala, Nader E. Abo-Dya, Tarek S. Ibrahim, Said A. El-Feky, Kapil Gyanda,

Keyur M. Pandya; J. Org. Chem. 2011; 76: 85-96; DOI: 10.1021/jo1015757.

f Benzotriazole-Assisted Solid-Phase Assembly of Leu-Enkephalin, Amyloid

segment 34-42, and other “Difficult” Peptide Sequences; Alan R. Katritzky,

Danniebelle N. Haase, Jodie V. Johnson, Alfred Chung; J. Org. Chem. 2009; 74:

2028-2032; DOI: 10.1021/jo8026214.

f The Efficient Preparation of Di- and Tripeptides by Coupling N-(Cbz- or

Fmoc-alpha-aminoacyl)benzotriazoles with Unprotected Amino Acids; Alan

R. Katritzky, Parul Angrish, Kazuyuki Suzuki; Synthesis 2006; 3: 411–424; DOI:

10.1055/s-2006-926287.

References:

Send us your inquiry!

(S)(S) N

O

(S)(S)HN

OH

Boc

N N

drug link



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BAAX001 Boc-L-Ala-Bt BAAX001.0001 1 g € 300,00

BAAX001.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

N-alpha-t-Butyloxycarbonyl-L-alanine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

14H

18N

4O

3

MOLECULAR WEIGHT: 290,32 g/moleSYNONYMS: (S)-t-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxopropan-2-ylcarbamate

BAAX016 Boc-L-Arg(Tos)-Bt BAAX016.0001 1 g € 450,00

BAAX016.0005 5 g € 1750,00N(S)(S)

OHNO

O

NH

HN NH

N N

S

O O

N-alpha-t-Butyloxycarbonyl-N-gamma-4-toluolsulfonyl-L-arginine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

24H

31N

7O

5S

MOLECULAR WEIGHT: 529,61 g/moleSYNONYMS: (S)-tert-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo- 5-(3-tosylguanidino)pentan-2-ylcarbamate

BAAX007 Boc-L-Asn-Bt BAAX007.0001 1 g € 300,00

BAAX007.0005 5 g € 1200,00N(S)(S)

OHNO

O N NO

NH2

N-alpha-t-Butyloxycarbonyl-L-asparagine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

15H

19N

5O

4

MOLECULAR WEIGHT: 333,34 g/moleSYNONYMS: (S)-t-butyl 4-amino-1-(1H-benzo[d][1,2,3]triazol-1-yl)-1,4-dioxobutan-2-ylcarbamate

BAAX015 Boc-L-Asp(Bzl)-Bt BAAX015.0001 1 g € 375,00

BAAX015.0005 5 g € 1450,00N(S)(S)

OHNO

O N NO

O

N-alpha-t-Butyloxycarbonyl-L-aspartic acid-alpha-(1H-benzo[d][1,2,3]triazol-1-yl), beta-benzyl diesterFORMULA: C

22H

24N

4O

5

MOLECULAR WEIGHT: 424,45 g/moleSYNONYMS: (S)-benzyl 4-(1H-benzo[d][1,2,3]triazol-1-yl)- 3-(tert-butoxycarbonylamino)-4-oxobutanoate

BAAX019 Boc-L-Cys(Bzl)-Bt please inquire!

N(R)(R)

OHN

SO

O

N N

N-alpha-t-Butyloxycarbonyl-S-benzyl-L-cysteine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

21H

24N

4O

3S

MOLECULAR WEIGHT: 412,51 g/moleSYNONYMS: (R)-tert-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(benzylthio)- 1-oxopropan-2-ylcarbamate

BAAX014 Boc-L-Glu(Bzl)-Bt BAAX014.0001 1 g € 375,00

BAAX014.0005 5 g € 1450,00N(S)(S)

OHN

OO

O

O N N

N-alpha-t-Butyloxycarbonyl-L-glutamic acid-alpha-(1H-benzo[d][1,2,3]triazol-1-yl), gamma-benzyl diesterFORMULA: C

23H

26N

4O

5

MOLECULAR WEIGHT: 438,48 g/moleSYNONYMS: (S)-benzyl 5-(1H-benzo[d][1,2,3]triazol-1-yl)- 4-(tert-butoxycarbonylamino)-5-oxopentanoate

BAAX008 Boc-L-Gln-Bt BAAX008.0001 1 g € 300,00

BAAX008.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

O NH2

N-alpha-t-Butyloxycarbonyl-L-glutamine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

16H

21N

5O

4

MOLECULAR WEIGHT: 347,37 g/moleSYNONYMS: (S)-t-butyl 4-amino-1-(1H-benzo[d][1,2,3]triazol-1-yl)- 1,5-dioxopentan-2-ylcarbamate

Article No. Quantity Price

Available N-alpha-Protected Amino Acids:

Boc-Protected Amino Acids

From Grams to Multi-Ton Lots



Tel.: +49-9231-9619-73 Fax: +49-9231-9619-99


Iris BIotech

BAAX009 Boc-Gly-Bt BAAX009.0001 1 g € 300,00

BAAX009.0005 5 g € 1200,00N

OHNO

O N N

N-alpha-t-Butyloxycarbonyl-glycine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

13H

16N

4O

3

MOLECULAR WEIGHT: 276,29 g/moleSYNONYMS: t-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxoethylcarbamate

BAAX018 Boc-L-His(Bzl)-Bt please inquire!N(S)(S)

OHNO

O

N

N

N NN-alpha-t-Butyloxycarbonyl-N-im-benzyl-L-histidine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

24H

26N

6O

3

MOLECULAR WEIGHT: 446,5 g/moleSYNONYMS: (S)-tert-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(1-benzyl-1H- imidazol-4-yl)-1-oxopropan-2-ylcarbamate

BAAX003 Boc-L-Ile-Bt BAAX003.0001 1 g € 300,00

BAAX003.0005 5 g € 1200,00N(S)(S)

O

(S)(S)

HNO

O N N

N-alpha-t-Butyloxycarbonyl-L-isoleucine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

17H

24N

4O

3

MOLECULAR WEIGHT: 332,4 g/moleSYNONYMS: t-butyl (2S,3S)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxopentan-2-ylcarbamate

BAAX004 Boc-L-Leu-Bt BAAX004.0001 1 g € 300,00

BAAX004.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

N-alpha-t-Butyloxycarbonyl-L-leucine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

17H

24N

4O

3

MOLECULAR WEIGHT: 332,4 g/moleSYNONYMS: (S)-t-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-4-methyl-1-oxopentan-2-ylcarbamate

BAAX013 Boc-L-Lys(Z)-Bt BAAX013.0001 1 g € 375,00

BAAX013.0005 5 g € 1450,00N(S)(S)

OHN

O

O

O

HN

N N

O

N-alpha-t-Butyloxycarbonyl-N-epsilon-benzyloxycarbonyl-L-lysine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

25H

31N

5O

5

MOLECULAR WEIGHT: 481,54 g/moleSYNONYMS: (S)-tert-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-6-(benzyloxycarbonylamino)-1-oxohexan-2-ylcarbamate

BAAX005 Boc-L-Met-Bt BAAX005.0001 1 g € 300,00

BAAX005.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

SMe

N-alpha-t-Butyloxycarbonyl-L-methionine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

16H

22N

4O

3S

MOLECULAR WEIGHT: 350,44 g/moleSYNONYMS: (S)-t-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-4-(methylthio)- 1-oxobutan-2-ylcarbamate

BAAX006 Boc-L-Phe-Bt BAAX006.0001 1 g € 300,00

BAAX006.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

N-alpha-t-Butyloxycarbonyl-L-phenylalanine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

20H

22N

4O

3

MOLECULAR WEIGHT: 366,41 g/moleSYNONYMS: (S)-t-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-ylcarbamate

BAAX010 Boc-L-Pro-Bt BAAX010.0001 1 g € 300,00

BAAX010.0005 5 g € 1200,00O

O

N(S)(S)

O N

N N

N-alpha-t-Butyloxycarbonyl-L-proline (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

16H

20N

4O

3

MOLECULAR WEIGHT: 316,36 g/moleSYNONYMS: (S)-t-butyl 2-(1H-benzo[d][1,2,3]triazole-1-carbonyl)pyrrolidine-1-carboxylate




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BAAX012 Boc-L-Ser(Bzl)-Bt BAAX012.0001 1 g € 375,00

BAAX012.0005 5 g € 1450,00N(S)(S)

OHNO

O N NO

N-alpha-t-Butyloxycarbonyl-O-benzyl-L-serine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

21H

24N

4O

4

MOLECULAR WEIGHT: 396,44 g/moleSYNONYMS: (S)-t-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-benzyloxy-1-oxopropan-2-ylcarbamate

BAAX020 Boc-L-Thr(Bzl)-Bt BAAX020.0001 1 g € 375,00

BAAX020.0005 5 g € 1450,00N(S)(S)

O

(R)(R)

HNO

O N NO

N-alpha-t-Butyloxycarbonyl-O-benzyl-L-threonine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

22H

26N

4O

4

MOLECULAR WEIGHT: 410,47 g/moleSYNONYMS: t-butyl (2S,3R)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-benzyloxy- 1-oxobutan-2-ylcarbamate

BAAX017 Boc-L-Trp(For)-Bt BAAX017.0001 1 g € 450,00

BAAX017.0005 5 g € 1750,00(S)(S)

O

HNN

N

OO

OH

N N

N-alpha-t-Butyloxycarbonyl-N‘-formyl-L-tryptophane (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

23H

23N

5O

4

MOLECULAR WEIGHT: 433,46 g/moleSYNONYMS: (S)-tert-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(1-formyl-1H-indol-3-yl)-1-oxopropan-2-ylcarbamate

BAAX011 Boc-L-Tyr(Bzl)-Bt BAAX011.0001 1 g € 375,00

BAAX011.0005 5 g € 1450,00N(S)(S)

OHNO

O N N

O

N-alpha-t-Butyloxycarbonyl-O-benzyl-L-tyrosine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

27H

28N

4O

4

MOLECULAR WEIGHT: 472,54 g/moleSYNONYMS: (S)-tert-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(4-(benzyloxy)phenyl)-1-oxopropan-2-ylcarbamate

BAAX002 Boc-L-Val-Bt BAAX002.0001 1 g € 300,00

BAAX002.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

N-alpha-t-Butyloxycarbonyl-L-valine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

16H

22N

4O

3

MOLECULAR WEIGHT: 318,37 g/moleSYNONYMS: (S)-t-butyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate


FAAX020 Fmoc-L-Ala-Bt FAAX020.0001 1 g € 300,00

FAAX020.0005 5 g € 1200,00

N(S)(S)

OHNO

O N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-alanine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

24H

20N

4O

3

MOLECULAR WEIGHT: 412,44 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)- 1-oxopropan-2-ylcarbamate

FAAX035 Fmoc-L-Arg(Pbf)-Bt FAAX035.0001 1 g € 450,00

FAAX035.0005 5 g € 1750,00N(S)(S)

OHNO

O

NH N

H

NH

S

O

O O

N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-N‘-2,2,4,6,7-pentamethyldihydro-benzofuran-5-sulfonyl-L-arginine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

40H

43N

7O

6S

MOLECULAR WEIGHT: 749,88 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-5-(3-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonyl)guanidino)pentan-2-ylcarbamate


Fmoc-Protected Amino Acids




Tel.: +49-9231-9619-73 Fax: +49-9231-9619-99


Iris BIotech

FAAX036 Fmoc-L-Asn(Trt)-Bt please inquire!

N(S)(S)

OHNO

O N NO

NH

N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-beta-trityl-L-asparagine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

44H

35NO

4

MOLECULAR WEIGHT: 697,78 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1,4-dioxo-4-(tritylamino)butan-2-ylcarbamate

FAAX032 Fmoc-L-Asp(tBu)-Bt FAAX032.0001 1 g € 375,00

FAAX032.0005 5 g € 1450,00N(S)(S)

OHNO

O N NO

O

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid-alpha- (1H-benzo[d][1,2,3]triazol-1-yl), beta-t-butyl diesterFORMULA: C

29H

28N

4O

5

MOLECULAR WEIGHT: 512,56 g/moleSYNONYMS: (S)-tert-butyl 3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-(1H-benzo[d][1,2,3]triazol-1-yl)-4-oxobutanoate

FAAX038 Fmoc-L-Cys(Trt)-Bt please inquire!

N(R)(R)

OHNO

O N NS

N-alpha-(9-Fluorenylmethyloxycarbonyl)-S-trityl-L-cysteine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

43H

34N

4O

3S

MOLECULAR WEIGHT: 686,82 g/moleSYNONYMS: (R)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-(tritylthio)propan-2-ylcarbamate

FAAX033 Fmoc-L-Glu(tBu)-Bt FAAX033.0001 1 g € 375,00

FAAX033.0005 5 g € 1450,00N(S)(S)

OHNO

O N N

O O

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-glutamic acid-gamma-t-butyl ester (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

30H

30N

4O

5

MOLECULAR WEIGHT: 526,58 g/moleSYNONYMS: (S)-tert-butyl 4-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-(1H-benzo[d][1,2,3]triazol-1-yl)-5-oxopentanoate

FAAX037 Fmoc-L-Gln(Trt)-Bt please inquire!N(S)(S)

OHNO

O N N

O NH

N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-gamma-trityl-L-glutamine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

45H

37N

5O

4

MOLECULAR WEIGHT: 711,81 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1,5-dioxo-5-(tritylamino)pentan-2-ylcarbamate

FAAX026 Fmoc-Gly-Bt FAAX026.0001 1 g € 300,00

FAAX026.0005 5 g € 1200,00

N

OHNO

O N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-glycine (1H-benzo[d][1,2,3]triazol-1-yl) esterCAS-NO: 1082989-49-8FORMULA: C

23H

18N

4O

3

MOLECULAR WEIGHT: 398,41 g/moleSYNONYMS: (9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxoethyl-carbamate

FAAX040 Fmoc-L-His(Boc)-Bt please inquire!

N(S)(S)

OHNO

O

N

N

O O

N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-im-(t-butyloxycarbonyl)- L-histidine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

32H

30N

6O

5

MOLECULAR WEIGHT: 578,62 g/moleSYNONYMS: (S)-tert-butyl 4-(2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1H-benzo[d][1,2,3]triazol-1-yl)-3-oxopropyl)-1H-imidazole-1-carboxylate




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FAAX022 Fmoc-L-Ile-Bt FAAX022.0001 1 g € 300,00

FAAX022.0005 5 g € 1200,00

N(S)(S)

O

(S)(S)

HNO

O N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-isoleucine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

27H

26N

4O

3

MOLECULAR WEIGHT: 454,52 g/moleSYNONYMS: (9H-fluoren-9-yl)methyl (2S,3S)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxopentan-2-ylcarbamate

FAAX023 Fmoc-L-Leu-Bt FAAX023.0001 1 g € 300,00

FAAX023.0005 5 g € 1200,00

N(S)(S)

OHNO

O N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-leucine (1H-benzo[d][1,2,3]triazol-1-yl) esterCAS-NO: 1072840-99-3FORMULA: C

27H

26N

4O

3

MOLECULAR WEIGHT: 454,52 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-4-methyl-1-oxopentan-2-ylcarbamate

FAAX031 Fmoc-L-Lys(Boc)-Bt FAAX031.0001 1 g € 375,00

FAAX031.0005 5 g € 1450N(S)(S)

OHN

HN O

O

O

O N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-t-butyloxycarbonyl- L-lysine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

32H

35N

5O

5

MOLECULAR WEIGHT: 569,65 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-6-(t-butyloxycarbonylamino)-1-oxohexan-2-ylcarbamate

FAAX024 Fmoc-L-Met-Bt FAAX024.0001 1 g € 300,00

FAAX024.0005 5 g € 1200,00

N(S)(S)

OHNO

O N N

SMe

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-methionine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

26H

24N

4O

3S

MOLECULAR WEIGHT: 472,56 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-4-(methylthio)-1-oxobutan-2-ylcarbamate

FAAX025 Fmoc-L-Phe-Bt FAAX025.0001 1 g € 300,00

FAAX025.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-phenylalanine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

30H

24N

4O

3

MOLECULAR WEIGHT: 488,54 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-ylcarbamate

FAAX027 Fmoc-L-Pro-Bt FAAX027.0001 1 g € 300,00

FAAX027.0005 5 g € 1200,00

O

O

N(S)(S)

O N

N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-proline (1H-benzo[d][1,2,3]triazol-1-yl) esterCAS-NO: 1155875-68-5FORMULA: C

26H

22N

4O

3

MOLECULAR WEIGHT: 438,48 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 2-(1H-benzo[d][1,2,3]triazole-1-carbonyl)pyrrolidine-1-carboxylate

FAAX029 Fmoc-L-Ser(tBu)-Bt FAAX029.0001 1 g € 375,00

FAAX029.0005 5 g € 1450,00N(S)(S)

OHNO

O N NO

N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-L-serine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

28H

28N

4O

4

MOLECULAR WEIGHT: 484,55 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-tert-butoxy-1-oxopropan-2-ylcarbamate





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FAAX030 Fmoc-L-Thr(tBu)-Bt FAAX030.0001 1 g € 375,00

FAAX030.0005 5 g € 1450,00N(S)(S)

O

(R)(R)

HNO

O N NO

N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-L-threonine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

29H

30N

4O

4

MOLECULAR WEIGHT: 498,57 g/moleSYNONYMS: (9H-fluoren-9-yl)methyl (2S,3R)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-tert-butoxy-1-oxobutan-2-ylcarbamate

FAAX034 Fmoc-L-Trp(Boc)-Bt FAAX034.0001 1 g € 450,00

FAAX034.0005 5 g € 1750,00N(S)(S)

OHNO

O

N

N N

O

O

N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-in-t-butyloxycarbonyl- L-tryptophane (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

37H

33N

5O

5

MOLECULAR WEIGHT: 627,69 g/moleSYNONYMS: (S)-tert-butyl 3-(2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1H-benzo[d][1,2,3]triazol-1-yl)-3-oxopropyl)-1H-indole-1-carboxylate

FAAX028 Fmoc-L-Tyr(tBu)-Bt FAAX028.0001 1 g € 375,00

FAAX028.0005 5 g € 1450,00N(S)(S)

OHNO

O N N

O

N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-L-tyrosine (1H-benzo[d][1,2,3]triazol-1-yl) esterCAS-NO: 1126433-42-8FORMULA: C

34H

32N

4O

4

MOLECULAR WEIGHT: 560,64 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(4-tert-butoxyphenyl)-1-oxopropan-2-ylcarbamate

FAAX021 Fmoc-L-Val-Bt FAAX021.0001 1 g € 300,00

FAAX021.0005 5 g € 1200,00

N(S)(S)

OHNO

O N N

N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-valine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

26H

24N

4O

3

MOLECULAR WEIGHT: 440,49 g/moleSYNONYMS: (S)-(9H-fluoren-9-yl)methyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate

ZAAX040 Z-L-Ala-Bt ZAAX040.0001 1 g € 300,00

ZAAX040.0005 5 g € 1200,00

N(S)(S)

OHNO

O N N

N-alpha-Benzyloxycarbonyl-L-alanine (1H-benzo[d][1,2,3]triazol-1-yl) esterCAS-NO: 820239-42-7FORMULA: C

17H

16N

4O

3

MOLECULAR WEIGHT: 324,33 g/moleSYNONYMS: (S)-benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxopropan- 2-ylcarbamate

ZAAX048 Z-L-Asn-Bt ZAAX048.0001 1 g € 300,00

ZAAX048.0005 5 g € 1200,00N(S)(S)

OHNO

O N NO

NH2

N-alpha-Benzyloxycarbonyl-L-asparagine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

18H

17N

5O

4

MOLECULAR WEIGHT: 367,36 g/moleSYNONYMS: (S)-benzyl 4-amino-1-(1H-benzo[d][1,2,3]triazol-1-yl)-1,4-dioxobutan-2-ylcarbamate


Z-Protected Amino Acids



Tel.: +49-9231-9619-73 Fax: +49-9231-9619-99


ZAAX049 Z-L-Gln-Bt ZAAX049.0001 1 g € 300,00

ZAAX049.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

O NH2

N-alpha-Benzyloxycarbonyl-L-glutamine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

19H

19N

5O

4

MOLECULAR WEIGHT: 381,39 g/moleSYNONYMS: (S)-benzyl 4-amino-1-(1H-benzo[d][1,2,3]triazol-1-yl)-1,5-dioxopentan-2-ylcarbamate

ZAAX046 Z-Gly-Bt ZAAX046.0001 1 g € 300,00

ZAAX046.0005 5 g € 1200,00

N

OHNO

O N N

N-alpha-Benzyloxycarbonyl-glycine (1H-benzo[d][1,2,3]triazol-1-yl) esterCAS-NO: 173459-80-8FORMULA: C

16H

14N

4O

3

MOLECULAR WEIGHT: 310,31 g/moleSYNONYMS: benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxoethylcarbamate

ZAAX042 Z-L-Ile-Bt ZAAX042.0001 1 g € 300,00

ZAAX042.0005 5 g € 1200,00

N(S)(S)

O

(S)(S)

HNO

O N N

N-alpha-Benzyloxycarbonyl-L-isoleucine (1H-benzo[d][1,2,3]triazol-1-yl) esterCAS-NO: 1072442-07-9FORMULA: C

20H

22N

4O

3

MOLECULAR WEIGHT: 366,41 g/moleSYNONYMS: benzyl (2S,3S)-1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxopentan-2-ylcarbamate

ZAAX043 Z-L-Leu-Bt ZAAX043.0001 1 g € 300,00

ZAAX043.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

N-alpha-Benzyloxycarbonyl-L-leucine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

20H

22N

4O

3

MOLECULAR WEIGHT: 366,41 g/moleSYNONYMS: (S)-benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-4-methyl-1-oxopentan-2-ylcarbamate

ZAAX044 Z-L-Met-Bt ZAAX044.0001 1 g € 300,00

ZAAX044.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

SMe

N-alpha-Benzyloxycarbonyl-L-methionine (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

19H

20N

4O

3S

MOLECULAR WEIGHT: 384,45 g/moleSYNONYMS: (S)-benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-4-(methylthio)-1-oxobutan-2-ylcarbamate

ZAAX045 Z-L-Phe-Bt ZAAX045.0001 1 g € 300,00

ZAAX045.0005 5 g € 1200,00N(S)(S)

OHNO

O N N

N-alpha-Benzyloxycarbonyl-L-phenylalanine (1H-benzo[d][1,2,3]triazol-1-yl) esterCAS-NO: 769922-77-2FORMULA: C

23H

20N

4O

3

MOLECULAR WEIGHT: 400,43 g/moleSYNONYMS: (S)-benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-ylcarbamate

ZAAX047 Z-L-Pro-Bt ZAAX047.0001 1 g € 300,00

ZAAX047.0005 5 g € 1200,00O

O

N(S)(S)

O N

N N

N-alpha-Benzyloxycarbonyl-L-proline (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

19H

18N

4O

3

MOLECULAR WEIGHT: 350,37 g/moleSYNONYMS: (S)-benzyl 2-(1H-benzo[d][1,2,3]triazole-1-carbonyl)pyrrolidine-1-carboxylate

ZAAX041 Z-L-Val-Bt ZAAX041.0001 1 g € 300,00

ZAAX041.0005 5 g € 1200,00

N(S)(S)

OHNO

O N N

N-alpha-Benzyloxycarbonyl-L-valine (1H-benzo[d][1,2,3]triazol-1-yl) esterCAS-NO: 820239-44-9FORMULA: C

19H

20N

4O

3

MOLECULAR WEIGHT: 352,39 g/moleSYNONYMS: (S)-benzyl 1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate





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Iris BIotech

LS-X050 Biotin-Bt LS-X050.0001 1 g € 200,00

LS-X050.0005 5 g € 600,00

SHN

HNO

H

HO

N

N N

Biotin (1H-benzo[d][1,2,3]triazol-1-yl) esterFORMULA: C

16H

19N

5O

2S

MOLECULAR WEIGHT: 345,52 g/moleSYNONYMS: (3aS,4S,6aR)-4-(5-(1H-benzo[d][1,2,3]triazol-1-yl)-5-oxopentyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one

RL-1006 Biotin-OSu RL-1006.0001 1 g € 85,00

RL-1006.0005 5 g € 300,00

RL-1006.0025 25 g € 1200,00S

HN

HNO

H

HO

ON

O

O

N-HydroxysuccinimidobiotinCAS-NO: 35013-72-0FORMULA: C

14H

19N

3O

5S

MOLECULAR WEIGHT: 341,39 g/moleSYNONYMS: D-Biotin N-hydroxysuccinimide ester, (+)-Biotin-NHS, NHS-biotin

LS-X051 Biotin-NHNH2 LS-X051.0001 1 g € 250,00

LS-X051.0005 5 g € 900,00

SHN

HNO

H

HO

NH

NH2Biotin hydrazideFORMULA: C

10H

18N

4O

2S

MOLECULAR WEIGHT: 258,34 g/moleSYNONYMS: 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanehydrazide

RL-2030 Biotin cadaverine RL-2030.0001 1 g € 350,00

RL-2030.0005 5 g € 1400,005-(Biotinamido)pentylamineFORMULA: C

15H

28N

4O

2S

MOLECULAR WEIGHT: 328,47 g/mole


Available Biotinylating Reagent Superior to Biotin-NHS:

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NNH

OO

O

OH

O

OO

N3O

O OH

O

NN

HN

NH

O O

O O

OO

O

SHN

HNO

H

HO

NH

NH2

N

N

O

O

OHN

N

O

O

Date post:	30-Mar-2016
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Benzotriazole Amino Acids

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