BIBLIOGRAPHIC UPDATE: Growth Inhibitors

A product of the CABS database. More than 2000 periodicals in the biological sciences are scanned regularly and the articles classified by trained scientists into convenient subject areas. Bibliographic update will give a comprehensive review ofcurrent literature for particular growth factors approximately every two

years. Articles are listed in date order of publication with the latest articles first. The entire CABS database, covering all the biological sciences, is available and searchable on-line via hosts BRS and ORBIT search service. Further details may be obtained from MAXWELL ONLINE, Achilles House, Western Avenue,

London W3 OUA, U.K. and 8000 Westpark Drive, McLean, VA 22102, U.S.A.

Copyright 0 1993 Pergamon Press Ltd

Binas B, Spitzer E, Zschieacbe W, Erdmann B, Kurtz A, M&r T, Nieman C, Blenau W, Grosse R. Hormonal

induction of functional differentiation and mammary-derived growth inhibitor expression in cultured mouse mammary gland explants. In Vitro Cell Dev Biol Anim. 1992; 28: 625-634.

Macieira-Co&o A, Soderberg A. Growth inhibitory activity in extracts from human fibroblasts. I Cell Physiol. 1993; 154: 92-100.

Cataldi A, Lisio R, Rana R, Bareggi R, Tulipano G, Miscia S. Interferon rapidly induces modifications of chromatin sensitivity to DNase I in Daudi lymphoma cells. Exp Cell Res. 1993: 204: 167-l 69. Robinson S, Lenfant M, Wdzieczzak-Bakala J, Melville J, Riches A. The mechanism of action of the

tetrapeptide Acetyl-N-ser-Asp-Lys-Pro (AcSDKP) in the control of haematopoietic stem cell proliferation. Cell Pro&f 1992; 25: 623-632. Porter J G, Catalano R, McEnroe G, Lewicki J A, Protter A. A C-type natriuretic peptide inhibits growth

factor-dependent DNA synthesis in smooth muscle cells Am J Physiol. 1992; 263: ClOOl-Cl106. Yong V W, Tejadaberges T, Goodyer C G, Ante1 J P, Yong F P. Differential proliferative response of human and mouse astrocytes to gamma-interferon. Glia. 1992; 6: 269-280. Bandtiow C E, Schmidt M F, Hassinger T D, Schwab M E, Kater S B. Role of intracellular calcium in NI-35. evoked collapse of neuronal growth cones. Science 1993; 259,509l; 77-79.

Igarashi M, Strittmatter S M, Vartanian T, Fishman M C. Mediation by G proteins of signals that cause collapse of growth cones. Science 1993; 259, 5091; 77-9. Abe A, Wu D, Shayman J A, Radin N S. Metabolic effects of short-chain ceramide and glucosylceramide on

sphingolipids and protein kinase C. Eur J Biochem. 1992; 210: 765-773. Schmidt A, Lemming G, Yoshida K, Buddecke E. Molecular organization and antiproliferative domains of arterial tissue heparan sulfate. Eur J Cell Biol. 1992; 59: 322-328.

Florio T, Pan Ming Gui, Newman B, Hershberger R E, CiveUi 0, Stork P J S. Dopaminergic inhibition of DNA synthesis in pituitary tumor cells is associated with phosphotyrosine phosphatase activity. J Biol Chem. 1992; 267: 24169-24172.

Stanulis-Praeger B M, Yaar M, Gilchrest B A. Evidence that tilopodia outgrowth is a common final pathway for fibroblsast growth inhibition in virro. Exp Dertnatol. 1992; 1: 141-148. Wang L J, Branm%om M, Robertson S A, Norman R J. Tumor necrosis factor alpha in the human ovary-Presence

in follicuiar fluid and effects on cell proliferation and prostaglandin product. Fertil Steril. 1992; 58: 934-940. Brandt R, Grosse R. Purification of a mammary-derived growth inhibitor (MDGI) related polypeptide expressed during pregnancy. Biochem Biophys Res Commun. 1992; 189: 40&413.

Tsuji S, Kobayashi H, Uchida Y, Ihara Y, Miyatake T. Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer’s disease. EMBO J. 1992; II: 48434850. Zhu Dapang, Kidder G M, Caveney S, Naus C C G. Growth retardation in glioma cells cocultured with cells overexpressing a gap junction protein. Proc Nut1 Acad Sci USA. 1992; 89: 10218-10221.

Koike K, Ma Feng, Shiohara M, Kubo T, Takagi M, Amano Y, Nakahata T, Komiyama A. Interferon-gamma inhibits proliferation. but not commitment, of murine granulocyte-macrophage progenitors. J Cell Physiol. 1992; 153: 528-533. Sage E H. Secretion of SPARC by endothelial cells transformed by polyoma middle T oncogene inhibits the

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growth of normal endothelial cells in vitro. Biochem Cell Biol. 1992; 70: 579-592. KIoke 0, Morltz T, Kummer G, Hust H, Ross B, Seeber S, Niederle N. Opposite sensitivity to the antiproliferative action of interferon-alpha and granulocyte-macrophage colony-stimulating factor in monoblastic U937 cells. J Interferon Res. 1992: 12: 369-376. Matzuk M M, Finegold M J, Su Jyan Gwo J, Hsueh A J W, Bradley A. Alpha-Inhibin is a tumour- suppressor gene with gonadal specificity in mice. Narure 1992; 360: 3 13-3 19. Han Z C, Maurer A M, Bellucci S, Wan Hai Y, Kroviarski Y, Bertrand 0, Caen J P. Inhibitory effect of platelet factor 4 (PF4) on the growth of human erythroleukemia cells: Proposed mechanism of action of PF4. J Lab Clin Med. 1992; 120: 645-660. Greinix H T, Storb R, Bartelmez S H. Specific growth inhibition of primitive hematopoietic progenitor cells mediated through monoclonal antibody binding to major histocompatibility class II molecules. Blood 1992; 80: 195G1956. Emara M, CarroB R G. Signal transduction through crosslinking CD7 and IgM-Fc receptors that inhibits T- cell proliferation. Hum Immunol. 1992; 34: 181-195. Malejczyk J, Malejczyk M, Kock A, Urbatukl A, Majewski S, Hunzebnann N, Jablomka S, Orth G, Luger T A. Autocrine growth limitation of human papillomavirus type 16-harboring keratino-cytes by constitutively released tumor necrosis factor-alpha. J Immunol. 1991; 149: 2702-2708. Moses M A, Sudhalter J, Langer R. Isolation and characterization of an inhibitor of neovascularization from scapular chondrocytes. J Cell Biol. 1992; 119: 475482. Skopets B, Li J, Thatcher W W, Roberts R M, Hansen P J. Inhibition of lymphocyte proliferation by bovine trophoblast protein-l (type I trophoblast interferon) and bovine interferon-alpha, 1. Vet Immunol Immunopathol. 1992; 34: 81-96. Garg U C, Devi L, Tumdorf H, Goldfrank L R, Bansinath M. Effect of nitric oxide on mitogenesis and proliferation of cerebellar glial cells. Brain Res. 1992; 592: 208-212. Stefani M R, Dunlap J A, Yorek M A. Effect of L-fucose on proliferation and myo-inositol metabolism in cultured cerebral microvessel and aortic endothelial cells. J Cell Physiol. 1992; 153: 321-331. James R I, Menaya J, Hudson K, Devalia V, Ryves J, Evans F J, Thomas S, Clemens M J. Role of protein kinase C in induction of gene expression and inhibition of cell proliferation by interferon alpha. Eur J Biochem. 1992; 209: 8 13-822. Slominski A, Goodmansnitkolf G. DOPA inhibits induced proliferative activity of murine and human lymphocytes, Anticancer Res. 1992; 12: 753-756. Broxmeyer H E. H-ferritin: A regulatory cytokine that down-modulates cell proliferation. J Lab Clin Med. 1992; 120: 367-370 Ushmorov A A, Danilov A 0, Zubova S G, Elgjo K, Okulov V B. Modulation of KB and A43 1 cell adhesion by epidermal growth inhibitory pentapeptide. Virchows Arch B 1992; 62: 353-356. Riedy M C, Stewart C C. Inhibitory role of interleukin-6 in macrophage proliferation. J Leukocyte Biol. 1992; 52: 125-127. Kim J H, Seibel M M, MacLaughlin D T, Donahoe P K, Ransil B J, Hametz PA, Richards C J. The inhibitory effects of Mullerian-inhibiting substance on epidermal growth factor induced proliferation and progesterone production of human granulosa-luteal cells. J Clin Endocrinol Metab. 1992; 75: 91 l-91 7. Fukuchi J I, Kashiwagl K, Kusama-Egucbl K, Terao K, Shlrahata A, Igarashi K. Mechanism of the inhibition of cell growth by N’,N’*-bis(ethyl)spermine. Eur J Biochem. 1992; 209: 689-696. Nunokawa Y, Tanaka S. Interferon-gamma inhibits proliferation of rat vascular smooth muscle cells by nitric oxide generation. Biochem Biophys Res Commun. 1992; 188: 409415. Diaz-Gallo C, Moscovitch-Lopatin M, Strom T B, Kelley V R. An anergic. islet-infiltrating T-cell clone that suppresses murine diabetes secretes a factor that blocks interleukin Z/interleukin 4-dependent proliferation. Proc Narl Acad Sci USA. 1992; 89: 86568660. Muller K, Rieneck K, Hansen M B, Bendtzen K. 1,25-Dihydroxyvitamin D,-mediated suppression of T lymphocyte functions and failure of T cell-activating cytokines to restore proliferation. Immunol Left. 1992; 34: 3744. Schmidt A, Yoshida K, Buddecke E. The antiproliferative activity of arterial heparan sulfate residues in domains enriched with 2-O-sulfated uranic acid residues. J Biol Chem. 1992; 267: 19242-19247. Petrelh C, Moretti P, Petrelli F, Bramucci M. A low molecular weight calf pineal peptide with an inhibiting effect on the growth of Ll210 and HL60 cells. Cell Biol Int Rep. 1992; 16: 967-974. Bielawska A, Linardic C M, Hannun Y A. Ceramide-mediated biology. Determination of structural and stereospecific requirements through the use of N-acyl-phenylaminoalcohol analogs. J Biol Chem. 1992; 267: 18493318497.

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Iwabuchi N, Williams D B, Nguyen H P, Wu YongjIan, Tisch R, Azuma T, Phillips M J, Hozumi N. Membrane region of surface IgM is not sufficient for transducing growth inhibitory signals in an immature B

cell line WEH1-23 1. Eur J Immunol. 1992; 22: 2507-25 1 I.

Akedo Y, Hosoi T, Inoue S, Ikegand A, Mizuno Y, Kaneki M, Nakamura T, Ouchi Y, Orimo H. Vitamin K, modulates proliferation and function of osteoblastic cells in vitro. Biochem Biophys Res Commun. 1992: 187:

814-820.

Ordog T, Vertes 2, Vertes M. Inhibition of oestradiol-induced DNA synthesis by opioid peptides in the rat uterus. Life Sci. 1992; 51: 1187-l 196.

Graham G J, Freshney M G, Donaldson D, Pragnell I B. Purification and biochemical characterisation of human and murine stem cell inhibitors (SCI). Growth Factors 1992; 7: 151-160.

Barzu T, DesmouIiere A, Herbert J M, Level M, Herault J P, Petitou M, Lormeau J C, Gabbiani G, Pascal M. O-acylated heparin derivatives with low anticoagulant activity decrease proliferation and increase alpha-

smooth muscle actin expression in cultured arterial smooth muscle cells. Eur J Pharmacol. 1992; 219: 225-

233. Hamdan H F, Luikart S D. Bone marrow matrix promotes differentiation and prolongs the cell cycle of U-

937 [U937] cells. Oncol Res. 1992; 4: 201-207.

Barg J, Belcbeva M M, Coscia C J. Evidence for the implication of phosphoinositol signal transduction in

mu-opioid inhibition of DNA synthesis. J Neurochem. 1992; 59: 1145-l 152. Meulders Q, He C J, Adida C, Peraldi M N, Schleuning W D, Sraer J D, Rondeau E. Tumor necrosis factor

alpha increases antifibrinolytic activity of cultured human mesangial cells. Kidney In!. 1992; 42: 327-334.

Louis J C, Muir D. Varon S. Autocrine inhibition of mitotic activity in cultured oligodendrocyte-type-2 astrocyte (0.2A) precursor cells. GIiu 1992; 6: 3&38.

Calvaruso G, Vento R, Taibi G, GiulIano M, Tesoriere G. A factor derived from chick embryo retina which

inhibits DNA synthesis of retina itself. Neurochem Res. 1992; 17: 1041-1048. Lindqvist C, Dabl C, Back C, Oker-Blom C, Akerman K, Wigzell H. Normal mouse serum-derived factor(s)

which inhibits growth of the interleukin-2-dependcent cell line CTLL. Eur J Haemafol. 1992; 49: 3-5. Kumar R, Atlas I. Interferon alpha induces the expression of retinoblastoma gene product in human Burkitt

lymphoma Daudi cells: Role in growth regulation. Proc Nut1 Acud Sci USA. 1992; 89: 65994603.

Potter-Perigo S, Braun K, Schonherr E, Wigbt T N. Altered proteoglycan synthesis via the false acceptor pathway can be dissociated from beta-n-xyloside inhibition of proliferation. Arch Biochem Biophys. 1992:

297: 101-109.

Kapfhammer J P, Schwab M E, Schneider G E. Antibody neutralization of neurite growth inhibitors from oligodendrocytes results in expanded pattern of postnatally sprouting retinocollicular axons. J Neuroscr.

1992; 12: 2112-2119. Dyer D, Tigyi G, Miledi R. The effect of active serum albumin on PC12 cells: II. Intracellular Ca” transients

and their role in neurite retraction. MO/ Brain Res. 1992; 14: 302-309.

Dyer D, Tigyi G, Miledi R. The effect of active serum albumin on PC12 cells: I. Neurite retraction and activation of the phosphoinositide second messenger system. Mel Brain Res. 1992; 14: 293-301. MacLaughlIn D T, Hudson P L, Graciano A L, KenneaBy M K, Ragin R C, Manganaro T F, Donahoe P K.

Mullerian duct regression and antiproliferative bioactivities of Mullerian inhibiting substance reside in its carboxy-terminal domain. Endocrinology 1992; 131: 291-296.

Ammar A, Sahraoui Y, Tsapis A, Bertoli A M, Jasmin C, GeorgouIias V. Human immunodeficiency virus- infected adherent cell-derived inhibitory factor (~29) inhibits normal T cell proliferation through decreased

expression ofhigh affinity interleukin-2 receptors and production of interleukin-2. J C/in Invest. I992; 90: 8- 14.

Wang H, Sullivan A K. Effects of a fibroblast-derived inhibitor on the growth of normal marrow and leukemic clonogenic cells. Leuk Res. 1992; 16: 693-70 1.

Ragin R C, Donahoe P K, Kemteally M K, Ahmad M F, MaeLaughlin D T. Human Mullerian inhibiting substance-Enhanced purification imparts biochemical stability and restores antiproliferative effects. Prolein Ekpression Purificar. 1992; 3: 236-245. Wells V, Mallucci L. Cell cycle regulation (Gl) by autocrine interferon and dissociation between autocrine interferon and 2’. 5’-oligoadenylate synthetase expression. J Interferon Res. 1992; Special issue: 51-60.

Palmer H, Libby P. Interferon-beta. A potential autocrine regulator of human vascular smooth muscle cell growth. L,ab Invest. 1992; 66: 715-721, Wells V, Msillucci L. Molecular expression of the negative growth factor murine beta-galactoside binding protein (mGBP). BEA Protein Struct Mel Enzymol. 1992; 1121: 239-244.

Norioka K I, Borden E C, Auerbach R. Inhibitory effects of cytokines on vascular endothelial cells: Synergistic

294 Bibliographic Update: Growth Inhibitors

interactions among interferon-gamma, tumor necrosis factor-alpha, and interleukin- 1. J Immunother. 1992; 12: 13-18. Asai K, Hirano T, Kaneko S, Moriyama A, Nakanishi K, lsobe I, Eksioglu Y Z, Kato T. A novel glial growth inhibitory factor, gliostatin, derived from neurofibroma. J Neurochem. 1992; 59: 307-317. Cocks B G, Vairo B, Bodrug S E, Hamilton J A. Suppression of growth factor-induced CYLl cyclin gene expression by antiproliferative agents. J&of Chem. 1992; 267: 12307-12310. Rogalsky V, Todorov G, Den T, Otu~um~ T. Increase in protein kinase C activity is associated with human fibroblast growth inhibition. FEBS Left. 1992; 304: 153-156. Paine R III, Chavis A, Gaposchkin D, Christensen P, Mody C H, Turka L A, Tnews G B. A factor secreted by a human pulmonary alveolar epithelial-like cell line blocks T-cell proliferation between G, and S phase. Am

J Respir Cell Mel Biol. 1992; 6: 658-666. Hassoun P M, Shedd A L, Lanzillo J J, Thappa V, Landman M J, Fanburg B L. Inhibition of pulmonary artery smooth muscle cell growth by hypoxanthine, xanthine, and uric acid. Am J Respir Cell h4ol Biol. 1992; 6: 617624. Graham G J, Pragnell I B. SCI/MIP- lalpha: A potent stem cell inhibitor with potential roles in development. Dev Biol. 1992; 151: 377-381. Vairo G, Royston A K, Hamilton J A. Biochemical events accompanying macrophage activation and the inhibition ofcolony-stimulating factor- 1 -induced macrophage proliferation by tumor necrosis factor-alpha, interferon-gamma, and lipopolysaccharide. J Cell Physiol. 1992; 15 1: 63&641. Calder P C, Newshohne E A. Polyunsaturated fatty acids suppress human peripheral blood lymphocyte proliferation and interleukin-2 production. Clin Sci. 1992; 82: 695-700. Arsura M, Introna M, Passerini F, Mantovani A, Golay J. B-myb antisense oligonucleotides inhibit proliferation of human hematopoietic cell lines. Blood 1992; 79: 2708-2716.

Thompson M P, Farrell H M Jnr, Mohanam S, Liu S, Kidwell W R, Bansal M P, Cook R G, Medina D, Kotts C E, Bano M. Identification of human milk alpha-lactalbumin as a cell growth inhibitor. Protoplasma 1992; 167: 134-144. Wright E G, Pragnell I B. The stem cell compartment: Assays and negative regulators. Curr Top Microbial

Immunol. 1992; 177: 137-149.

Ayroldi E, Blasi E, Varesio L, Wiltrout R H. Inhibition of proliferation of retrovirus-immortalized macrophages by LPS and IFN-gamma: Possible autocrine down-regulation of cell growth by induction of IL1 and TNF. Biotherapy 1992; 4: 267-276.

Cataldi A, Santavenere E, Vitale M, Tnrbiani 0, Lisio R, TuUpano G, Di Domenicantonio L, Zamai L, Miscia S. Interferon affects cell growth progression by modulating DNA polymerases activity. Cell Pro/if. 1992; 25: 225-23 1. Koo P H, Liebl D J. Inhibition of nerve growth factor-stimulated neurite outgrowth by methylamine- modified alpha 2-macroglobulin. J Neurosci Res. 1992; 31: 678692. Totpal K, Agarwal S, Aggarwal B B. Phosphatase inhibitors modulate the growth-regulatory effects of human tumor necrosis factor on tumor and normal cells. Cancer Res. 1992; 52: 2557-2562. Broxmeyer H E. Suppressor cytokines and regulation of myelopoiesis. Biology and possible clinical uses. Am

J Pediatr Hematol Oncol. 1992; 14: 22-30. Wang J C, Lang H D, Liao P, Wong A. Recombinant alpha-interferon inhibits colony formation of bone marrow tibroblast progenitor cells (CFU-F). Am J Hematol. 1992; 40: 81-85.

Khuata H, Yoshlda A, Ishioka C, Jiang Y, Mlkawa H. Eosinophil cationic protein inhibits immunoglobulin production and proliferation in vitro in human plasma cells. CeN Zmmunol. 1992; 141: 422432. Gary K A, ChronwaU B M. The onset of dopaminergic innervation during ontogeny decreases melanotrope proliferation in the intermediate lobe of the rat pituitary. Int J Dev Neurosci. 1992; IO: 131-142. McCaffrey T A, Falcone D J, Barth W, Brayton C F, Weksler B B. Fucoidan is a non-anticoagulant inhibitor of intimal hyperplasia. Biochem Biophys Res Commun. 1992; 184: 773-781. Woodman A C, Selden C A, Hodgson H J F. Partial purification and characterisation of an inhibitor of hepatocyte proliferation derived from nonparenchymal cells after partial hepatectomy. J Cell Physiol. 1992; 151: 405-414. Gregoire F, De Broux N, Heuser N, Heremans H, Van Damme J, Remacle C. Interferon-gamma and interleukin-lbeta inhibit adipoconversion in cultured rodent preadipocytes. J Cell Ph.vsiol. 1992; 151: 300-

309. Pardee A B, Keyomarsl K. Modification of cell proliferation with inhibitors. Curr Opin Cell Biol. 1992; 4: 186191. Bruce J H, Ramirez A, Lin L, Agarwal R P. Effects of cyclic AMP and butyrate on cell cycle. DNA, RNA,

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and purine synthesis of cultured astrocytes. Neurochem Res. 1992; 17: 315-320. Grainger D J, Heaketh T R, Wiessherg P L, Metcalfe J C. Hexamethylenebisacetamide selectively inhibits the proliferation of human and rat vascular smooth-muscle cells. Biochem J. 1992; 283: 403408. Morre D J, Morre D M, Paulik M, Batova A, Broome A M, Pirisi L, Creek K E. Retinoic acid and calcitriol inhibition of growth and NADH oxidase of normal and immortalized human keratinocytes. BBA Mol Cell Res. 1992; 1134: 217-222. Lahuanach-Guard A C, ‘Ibibault G, Lacord M, Degeme D, Bardos P. Lipid and protein components of the syncytiotrophoblast plasma membrane inhibit lymphocyte proliferation by two distinct pathways. Immunol Left. 1992; 32: 131-138. Cook P W, Mattox P A, Keeble W W, Shipley G D. Inhibition of autonomous human keratinocyte proliferation and amphiregulin mitogenic activity by sulfated polysaccharides. In Vitro Cell Dev Biol Anim. 1992; 28: 218-222. Sakata N, Jiii S, Takebayasbi S, Marques M A. Type. V collagen represses the attachment, spread, and growth of porcine vascular smooth muscle cells in vitro. Exp Mol Pathol. 1992; 56: 20-36. Schweigerer L; Christeleit K, Fleischmann G, Adlercreutz H, Wahala K, Hase T, Schwab M, Ludwig R, Fotsis T. Identification in human urine of a natural growth inhibitor for cells derived from solid paediatric tumours. Eur J Clin Invest. 1992; 22: 26&264. Fargion S, Cappelfini M D, Fracanzani A L, De Feo T M, Levi S, Arosio P, Fiorelfi G. Binding and suppressive activity of human recombinant ferritins on erythroid cells. Am J Hematol. 1992; 264268. Rowley D R. Characterization of a fetal urogenital sinus mesenchymal cell line U4F: Secretion of a negative growth regulatory activity. In Vitro Cell Dev Biol Anim. 1992; 28: 29-38. Ericson K K, Yang T J. An inhibitor of tumor cell growth from normal horse serum. In Vitro Cell Dev Biol Anim. 1992; 28: 11-16. Lambert R D, Dufour M, Blouin L. Rabbit embryo-fetal fluid decreases the cell cycle activities of DU-145 [DU145] cells. Cell Prolif 1992; 25: 141-153. Ozes 0 N, Reiter Z, Klein S, Blatt L M, Taylor M W. A comparison of interferon-Con 1 with natural recombinant interferons-alpha-Antiviral, antiproliferative, and natural killer-inducing activities. J Interferon Res. 1992; 12: 55. Waine G J, Tymms M J, Brandt E R, Cheetham B F, Linnane A W. Structure-function study of the region encompassing residues-2640 of human interferon-alpha4-Identification of residues important for antiviral and antiproliferative activities. J Inferferon Res. 1992; 12: 4348. Scarozza A M, Collins T J, Evans S S. DNA synthesis in nuclei isolated from Daudi B-cells-A model to study the antiproliferative mechanisms of interferon-alpha. J Interferon Res. 1992; 12: 35-42. Politis 1, Gorewit R C, Muller T, Grosse R. Mammary-derived growth inhibitor in lactation and involution. Domest Anim Endocrinol. 1992: 9: 89-94. Bramucci M, Miano A, Amici D. Epidermal inhibitory pentapeptide phosphorylated in vitro by calf thymus protein kinase NII is protected from serum enzyme hydrolysis. Biochem Biophys Res Commun. 1992: 183: 474480.

Peled T, Rigel M, Peritt D, Fibach E, Treves A J, Barak V. Effect of M20 interleukin-I inhibitor on normal and leukemic human myeloid progenitors. Blood 1992; 79: 1172-l 177. Taga K, Tosato G. IL-IO inhibits human T cell proliferation and IL-2 production. J Immunol. 1992; 148: 1143-l 148. Au Y P T, Kenagy R D, Clowes A W. Heparin selectively inhibits the transcription of tissue-type plasminogen activator in primate arterial smooth muscle cells during mitogenesis. J Biol Chem. 1992; 268: 3438-3444. Gartner S L, Wilfkuns T J. Modulation of interleukin-I induced thymocyte proliferation by o-mannose. Th,vmus 1992; 19: 117-126. Ferrara N, Winer J, Henzel W J. Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth: identification as leukemia inhibitory factor. Proc Nut1 Acad Sci USA. 1992; 89: 698-702. Cole G J, McCabe C F.. Identification of a developmentally regulated keratan sulfate proteoglycan thdt

inhibits cell adhesion and neurite outgrowth. Neuron 1991; 7: 1007-1018. Schneiderschaulies J, Kirchhoff F, Arcbelos J, Schachner M. Down-regulation of myelin-associated glycoprotein on Schwann cells by interferon-gamma and tumor necrosis factor-alpha affects neurite outgrowth. Neuron 1991: 7: 995-1006. Spiering A L, Smith J R. Negative growth effecters and cellular senescence, Murar Res: DNAging 1991; 256: 2633270. Tiveron M C, Barboni E, River0 F B P, Cormley A M, Seeley P J, Grosveld F, Morris R. Selective inhibition of neurite outgrowth on mature astrocytes by Thy-l glycoprotein. Nofure 1992; 355: 745-748.

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Carson D D, Julian J, Jacobs A L. Uterine stromal cell chondroitin sulfate proteoglycans bind to collagen type I and inhibit embryo outgrowth in vitro. Dev &of. 1992; 149: 307-316. Wang X M, Li Y Y, Jin Q, Zhang Z Q, Hou Y D. A new human interferon-gamma mutant harboring EGF receptor-interfering sequence possesses high antiproliferative activity. Sci China Ser B-Chem Life Sci Earth

Sci. 1992; 35: 84-91. Kimura T, Miyasaki K, Yamasbita J, Horio T, Kakuuo T. Purification and partial characterization of two types of growth-inhibitory protein latently present in rabbit serum. EBA Protein Struct Mel Enzymol. 1992; 1118: 239-248. Fligiel S E G, Iuman D R, Talwar H S, Fisher G J, Voorhees J J, Varani J. Modulation of growth in normal and malignant melanocytic cells by all-trans retinoic acid. J Cutaneous Pathol. 1992; 19: 27-33. Nagel M D, Nagel J. Erythroid colony formation by fetal rat liver and spleen cells in vitro: Inhibition by a low relative molecular mass component of fetal spleen. Development 1992; 114: 213-219. Smitb C D, Wen D, Muoberry S L, Chang K J. Inhibition of phosphatidylinositol4-phosphate kinase by heparin. A possible mechanism for the antiproliferative effects of heparin. Biochem J. 1992; 281: 803-808. Evans C E, Ward C, Ratbour L, Galasko C B. Myeloma affects both the growth and function of human osteoblast-like cells. Clin Exp Metastasis 1992; 10: 33-38. Resnitzky D, Tiefenbnm N, Beriai H, Kbuchi A. Interferons and interleukin 6 suppress phosphorylation of the retinoblastoma protein in growth-sensitive hematopoietic cells. Proc Nut1 Acad Sci USA. 1992; 89: 402- 406. Pate1 K V, Schrey M P. Inhibition of DNA synthesis and growth in human breast stromal cells by bradykinin: Evidence for independent roles of B, and B, receptors in the respective control of cell growth and phospholipid hydrolysis. Cancer Res. 1992; 52: 334340. Cho-Chung Y S, Nesterova M V, Severin E S, Vinogradov S V. Chemical modification enhances the inhibitory effect of regulatory subunit antisense oligodeoxynucleotide of CAMP-dependent protein kinase type I on cell proliferation. Biochem Int. 1991; 25: 767-773. Edstrom A, Edbladh M, Ekstrom P. Adenosine inhibition of the regeneration in vitro of adult frog sciatic sensory axons. Bruin Res. 1992; 354 1. Muir D, Manthorpe M. Stromelysin generates a fibronectin fragment that inhibits Schwann cell proliferation. J Cell Biol. 1992; 116: 177-185. Holan V, Nakamura S, Minowada J. Inhibitiory versus stimulatory effects of natural human interferon- alpha on proliferation of lymphocyte subpopulations. Immunology 1992; 75: 176181. Calder P C, Bevan S J, Newslmhne E A. The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism. Immunology 1992; 75: 108- 115. Vittet D, Matbieu M N, Launay J M, Cbevfllard C. Thrombin inhibits proliferation of the human megakaryoblastic MEG-01 [MEG011 cell line: A possible involvement of a cyclic-AMP dependent mechanism. J Cell Physiol. 1992; 150: 65-75. Means R T Jr, Dessypris E N, Krantz S B. Inhibition of human erythroid colony-forming units by interleukin-1 is mediated by gamma interferon. J Cell Physiol. 1992; 150: 59-64. San Antonio J D, Lander A D, Wright T C, Karuovsky M J. Heparin inhibits the attachment and growth of Balb/c-3T3 [BALBC313] fibroblasts on collagen substrata. J Cell Physiol. 1992; 150: 8-16. Vento R, Calvaruso G, Maxia L, Tesoriere G. Purification of a fetal bovine serum factor that inhibits DNA synthesis in chick embryo retinas. Med Sci Res. 1992; 20: 4749. Crossin K L. Cytotactin binding: Inhibition of stimulated proliferation and intracellular alkalinization in fibroblasts. Proc Nut1 Acad Sci USA. 1991; 88: 11403-I 1407. Santavenere E, Cataldi A, Rana R, Vitale M, Lisio R, Di Domenicantonio L, Zamai L, Trubiani 0, Miscia S. Nuclear metabolic changes induced by tumor necrosis factor in Daudi lymphoma cells: A multiparametric analysis. Cell Biol Int Rep. 1991; 15: 123542. Nakagawa-Yagi Y, Saito Y, Takada Y, Nakamura H. Suppressive effect ofcarbachol on forskolin-stimulated neurite outgrowth in human neuroblastoma NB-OK1 [NBOKI] cells. Eiochem Biophys Res Commun. 1992; 182: 45-54. Hostmark A T, Lystad E. Growth inhibition of human hepatoma cells (HepG2) by polyunsaturated fatty acids. Protection by albumin and vitamin E. Acta Physioi &and. 1992; 144: 83-88. Vischer P, Buddecke E. Different action of heparin and fucoidan on arterial smooth muscle cell proliferation and thrombospondin and fibronectin metabolism. Eur J Cell Biol. 1991; 56: 407414. Plumb M, Grabam G J, Grove M, Reid A, PragneU I B. Molecular aspects of a negative regulator of haemopoiesis. Er J Cancer 1991; 64: 990992. Han 2 C, Belhtcci S, Bodevin E, Wan H Y, Shen Z X, Caen J P. In viva inhibition of megakaryocyte and

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platelet production by platelet factor 4 in mice. CR Acad Sci Ser III-Sci Vie 1991; 313: 553-558. Grabowska A, Regan L, Hawley S, Lake Y W. Human pregnancy sera from sequential stages of gestation are increasingly inhibitory to the growth of trophoblast cells in culture. Placenta 1991; 12: 549-552.

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Kasiske B L, Keane W F. Role of lipid peroxidation in the inhibition of mononuclear cell proliferation by normal lipoproteins. J Lipid Res. 1991; 32: 775-78 1. Lopez M, Wdzieczak-Bakala J, Pradelles P, Frindel E. Human placental low molecular weight factors inhibit the entry into cell cycle of murine pluripotent stem cells. Leukemia 1991; 5: 270-272.

Andress D L, Howard G A, Birnbaum R S. Identification of a low molecular weight inhibitor of osteoblast mitogenesis in uremic plasma. Kidney Int. 1991; 39: 942-945. Vairo G, Argyriou S, Knight K R, Hamilton J A. Inhibition of colony-stimulating factor-stimulated macrophage proliferation by tumor necrosis factor-alpha, IFN-gamma, and lipopolysaccharide is not due to a general loss of responsiveness to growth factor. J Immunol. 1991; 146: 3469-3477. Leschey K H, Hines J, Singer J H, Hackett S F, Campochiaro P A. Inhibition of growth factor effects in

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Fireman E, Efraim S 9, Messes G, Dabusb S, Greif J, Topilsky M. Cell-free supernatants of sarcoid alveolar macrophages suppress proliferation of sarcoid alveolar fibroblasts. C/in Itnmunol Immunopathol. 1991; 59:

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Eccleston P A, Mirsky R, Jessen K R. Spontaneous immortalisation of Schwann cells in culture: Short-term cultured Schwann cells secrete growth inhibitory activity. Developmenr 1991; 112: 3342.

Hampson J, Redmond S, Lord B I, Slocombe P, Ofarrell A M, Heywortb C M, Dexter T M. Selective

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Elgjo K, R&belt K L, Clausen 0 P F, de Angelis P. Inhibitory epidermal pentapeptide modulates proliferation and differentiation of transformed mouse epidermal cells in vitro, Virchow Arch B 1991; 60:

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Schwab M E, Schnell L. Channeling ofdeveloping rat corticospinal tract axons by myelin-associated neurite growth inhibitors. J Neurosci. 1991; 11: 709-721.

Bastmeyer M, Beckmnnn M, Schwab M E, Stuermer C A 0. Growth of regenerating goldfish axons is inhibited by rat oligodendrocytes and CNS myelin but not by goldfish optic nerve tract oligodendrocytelike

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Funk S E, Sage E H. The Ca2’-binding glycoprotein SPARC modulates cell cycle progression in bovine aortic endothelial cells. Proc Nurl Acad Sci USA. 1991; 88: 2648-2652.

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Pucci-Minafra 1, Luparello C. Type V/type I collagen interactions in vitro and growth-inhibitory effect of

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Stepien H, Kunert-Radek J, Stanisz A, Zerek-Melen G, Pawlikowski M. Inhibitory effect of porphyrins on

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Wells V, MaUucci L Identification of an autocrine negative growth factor: Mouse beta-galactoside-binding

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