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Paul Underwood, Principal Solution Architect - AWS
4.11.18
Biotech BlueprintHow ChemAxon and AWS simplify getting you moving on the cloud.
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About Me
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About Me
!=
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About You?
Who is using AWS today?
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About You?
Who is using AWS today?
What was it like getting started?
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
About You?
Who is using AWS today?
What was it like getting started?
Who is running ChemAxon on AWS today?
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
About You?
Who is using AWS today?
What was it like getting started?
Who is running ChemAxon on AWS today?
What other types of informatics tools are you using?
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
A typical Biotech’s journey
Preclinical
Infrastructure
Compute
Storage
Security/
Network
Chemistry
Biology
Lab
Ops
Systems
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
A typical Biotech’s journey
Preclinical
Infrastructure
Research Phase
Infrastructure
Compute
HIP
AA
/ S
OX
Storage
Security/
Network
HPC
Data Agg/
Mining
Core
Services
Image Data
Mgmt
Bio-repositoryChemistry
Biology
Lab
Ops
Translational
Pharm Dev
Pharmacology
Systems Systems
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
A typical Biotech’s journey
Preclinical
Infrastructure
Research Phase
Infrastructure
Clinical Phase
Infrastructure
Compute
HIP
AA
/ S
OX
21C
FR
11/G
xP
Analytics
DashboardsStorage
Security/
Network
HPC
Data Agg/
Mining
Core
Services
Development
Data Agg/
Mining
Core
Services
APIs NLP
ML
Image Data
Mgmt
Bio-repositoryChemistry
Biology
Lab
Ops
Translational
Pharm Dev
Pharmacology
Clinical
Regulatory
QA/QC
Safety
QMS
Systems Systems Systems
LMS
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
Points of Friction
Preclinical
Infrastructure
Research Phase
Infrastructure
Clinical Phase
Infrastructure
Compute
HIP
AA
/ S
OX
21C
FR
11/G
xP
Storage
Security/Network
HPC
Data Agg / Mining
Core Services
Development
Data Agg / Mining
Core Services
Biology
Lab Ops
Translational
Pharm Dev
Pharmacology
Clinical
Regulatory
QA/QC
Systems Systems Systems
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
Points of Friction
Preclinical
Infrastructure
Research Phase
Infrastructure
Clinical Phase
Infrastructure
Compute
HIP
AA
/ S
OX
21C
FR
11/G
xP
Storage
Security/Network
HPC
Data Agg / Mining
Core Services
Development
Data Agg / Mining
Core Services
Biology
Lab Ops
Translational
Pharm Dev
Pharmacology
Clinical
Regulatory
QA/QC
Systems Systems Systems
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
Platform Team
Who facilitates this?
Preclinical
Infrastructure
Research Phase
Infrastructure
Clinical Phase
Infrastructure
Compute
HIP
AA
/ S
OX
21
CFR
11
/GxP
Storage
Security/Network
HPC
Data Agg/Mining
Core Services
Development
Data Agg/Mining
Core Services
Biology
Lab Ops
Translational
Pharm Dev
Pharmacology
Clinical
Regulatory
QA/QC
Systems Systems Systems
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Platform Team
About that platform team…
What does yours look like?
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Platform Team
Here is what I usually see:
Common theme?
Researchers/
ScientistsLone Wolf Consultants
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Platform Team
Here is what I usually see:
Common theme?
Researchers/
ScientistsLone Wolf Consultants
• Small teams• Need to move
fast• Bringing the
company to the cloud
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That’s a problem.
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
Hold on a minute…
AWS• Knows what a Biotech’s
architecture looks like.
• Has deployable reference
architectures to match.
ISVs (Ex. ChemAxon)
• Knows what their
deployment looks like.
• Can automate
deployment into a
reference architecture.
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
What if…
AWS• Knows what a Biotech’s
architecture looks like.
• Has deployable reference
architectures to match.
ISVs (Ex. ChemAxon)
• Knows what their
deployment looks like.
• Can automate
deployment into a
reference architecture.AWS
CloudFormation
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
See where I’m going?
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Biotech Blueprint QuickStart
Infrastructure
Compute
Storage
Security/Network
Biology
Lab Ops
Systems
Preclinical
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
Biotech Blueprint QuickStart
Infrastructure
Compute
Storage
Security/Network
Biology
Lab Ops
Systems
Preclinical
Core Template:Preclinical VPC
Management VPC
VPN Solution
Public/Private Subnets
IAM Groups / Policies
Bastion Host
Config Rules
Audit and Logging
High Availability Controls
NAT
Internal DNS
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
Biotech Blueprint QuickStart
Infrastructure
Compute
Storage
Security/Network
Biology
Lab Ops
Systems
Preclinical
Core Template:Preclinical VPC
Management VPC
VPN Solution
Public/Private Subnets
IAM Groups / Policies
Bastion Host
Config Rules
Audit and Logging
High Availability Controls
NAT
Internal DNS
ISV Template
(Ex. ChemAxon)Application Server
Database Server
Load Balancer
DNS
Security Groups
Subnet Locations
Parameter store for intg.
Bootstrapping scripts
PrivateLink Endpoint (SaaS)
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Deployment?
Takes about 15
Minutes To
Deploy
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Deployment?
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TTDL; Biotech Blueprint is a force multiplier for small platform teams.
Do things right from day 0.
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
Interested?Wait 5 weeks. Or…[email protected]
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What’s Coming?
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
Infrastructure
Research Phase
Infrastructure
Clinical Phase
Infrastructure
Compute
HIP
AA
/ S
OX
21C
FR
11/G
xP
Analytics
DashboardsStorage
Security/Network
HPC
Data Agg/
Mining
Core
Services
Development
Data Agg/
Mining
Core
Services
APIs NLP
ML
Image Data
Mgmt
Bio-repository
Biology
Lab Ops
Translational
Pharm Dev
Pharmacology
Clinical
Regulatory
QA/QC
Safety
QMS
Systems Systems Systems
LMS
Whats next for the Biotech Blueprint?
Preclinical
More to Come!
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Have HIPAA / GxP Needs Now?
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Thanks to ChemAxon for being a leader in the cloud and being a Biotech Blueprint Launch Partner
© 2018, Amazon Web Services, Inc. or its Affiliates. All rights reserved.© 2017, Amazon Web Services, Inc. or its Affiliates. All rights reserved.
Thanks again!-Paul [email protected]
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Appendix.
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SaaSDeployment
