• Q&A with Mr Tomasi
• Cover two key general surgical emergencies
• Provide important differential diagnoses
• Pathophysiology, clinical features, investigations, management, prognosis
• Multi-step SBAs: for a full understanding of the patient journey
• Summary and Q&A
2
Aims and objectives
Introducing our special guest
3
Covered today…• Small bowel obstruction• Large bowel obstruction
Next time…• Appendicitis• Perforated peptic ulcer• Diverticulitis / diverticular bleeding• Ischaemic colitis and mesenteric ischaemia
5
Conditions to cover
6
Overview
CholecystitisUreteric colic
PyelonephritisHepatitis
Pneumonia
AppendicitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Ureteric colicPyelonephritis
Pneumonia
DiverticulitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction
Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm
© BiteMedicine 2020
7
Overview
CholecystitisUreteric colic
PyelonephritisHepatitis
Pneumonia
AppendicitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Ureteric colicPyelonephritis
Pneumonia
DiverticulitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction
Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm
© BiteMedicine 2020
8
Overview
CholecystitisUreteric colic
PyelonephritisHepatitis
Pneumonia
AppendicitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Ureteric colicPyelonephritis
Pneumonia
DiverticulitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction
Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm
© BiteMedicine 2020
9
Overview
CholecystitisUreteric colic
PyelonephritisHepatitis
Pneumonia
AppendicitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Ureteric colicPyelonephritis
Pneumonia
DiverticulitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction
Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm
© BiteMedicine 2020
History and examinationA 60-year-old female presents to the emergencydepartment with central abdominal pain,nausea and vomiting. The pain has been‘coming and going’.
She has had a previous open appendicectomy.
Examination reveals central abdominaltenderness with ‘tinkling’ bowel sounds andabdominal distension. The rectum is empty.
ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8
10
Case-based discussion: 1
11
A 60-year-old female presents to the emergency department with central abdominalpain, nausea and vomiting. The pain has been ‘coming and going’. She has had aprevious open appendicectomy. Examination reveals central abdominal tendernesswith ‘tinkling’ bowel sounds and abdominal distension. The rectum is empty.
ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8
Q1 Q2
What is the most common cause of the underlying diagnosis?
Case history
Volvulus
Incarcerated hernia
Colorectal cancer
Bowel adhesions
Crohn’s disease
app.bitemedicine.com
Q3 Q4
History and examinationA 60-year-old female presents to the emergencydepartment with central abdominal pain,nausea and vomiting. The pain has been‘coming and going’.
She has had a previous open appendicectomy.
Examination reveals central abdominaltenderness with ‘tinkling’ bowel sounds andabdominal distension. The rectum is empty.
ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8
13
Case-based discussion: 2
Definition• Small bowel obstruction (SBO) is a mechanical or functional obstruction of the small intestine that
prevents the normal passage of digestive contents
Epidemiology and risk factors• Rare in those without previous surgery (‘virgin’ abdomen)• Previous surgery increases risk by 12-fold• Average age is 60-years-old
14
Introduction
15
Very basic anatomy
16
Important causes
Causes Comments
Bowel adhesions: the most common cause Due to previous abdominal surgery
Incarcerated hernia Usually femoral or inguinal
Crohn’s disease Due to stricture formation
Volvulus Commonly causes large bowel obstruction
Intussusception More common in children
Paralytic ileus Functional obstruction due to failure of peristalsis
17
Important causes
Causes
Bowel adhesions: the most common cause
Incarcerated hernia
Crohn’s disease
Volvulus
Intussusception
Paralytic ileus
18
Linking pathophysiology and symptoms
© BiteMedicine 2020
19
Clinical features
Symptoms Signs
Colicky, central or generalised abdominal pain Abdominal tenderness and distension
Nausea and vomiting: an EARLY symptom in SBO
Tinkling bowel sounds
Bloating Rectal examination: rectum may be empty• Blood suggests strangulation and ischaemia
Absolute constipation: a LATE symptom in SBO Tachycardia and hypotension
20
Differentials
CholecystitisUreteric colic
PyelonephritisHepatitis
Pneumonia
AppendicitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Ureteric colicPyelonephritis
Pneumonia
DiverticulitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction
Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm
© BiteMedicine 2020
History and examinationA 60-year-old female presents to the emergencydepartment with central abdominal pain,nausea and vomiting. The pain has been‘coming and going’.
She has had a previous open appendicectomy.
Examination reveals central abdominaltenderness with ‘tinkling’ bowel sounds andabdominal distension. The rectum is empty.
ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8
21
Case-based discussion: 1
22
An abdominal X-ray is performed…
23
A 60-year-old female presents to the emergency department with central abdominalpain, nausea and vomiting. The pain has been ‘coming and going’. She has had aprevious open appendicectomy. Examination reveals central abdominal tendernesswith ‘tinkling’ bowel sounds and abdominal distension. The rectum is empty.
ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8
Q2Q1
What bowel diameter suggests small bowel dilatation on imaging?
Case history
> 6 cm
> 1 cm
> 3 cm
> 9 cm
> 12 cm
app.bitemedicine.com
Q3 Q4
25
Investigations
Primary investigations• Bloods:
• FBC: elevated white cell count with neutrophilia• U&Es: pre-renal AKI and assess for electrolyte imbalances (paralytic ileus)• CRP: usually raised• Group and save: patients may require surgery• VBG: to assess the degree of lactic/metabolic acidosis (suggests ischaemia)• Abdominal X-ray: first-line imaging; dilated small bowel loops (>3cm) with fluid levels
• CT abdomen and pelvis with contrast: gold standard imaging
Investigations to consider• Erect chest X-ray: to assess for pneumoperitoneum if concerned about perforation• Contrast studies: the patient can drink water-soluble contrast (e.g. gastrograffin) and have serial X-
rays; if the contrast fails to reach the colon this is an indication for surgery
26
What does the patient’s CT scan demonstrate?Q3
27
Management
“Never let the sun rise or set on small-bowel obstruction”
28
Management
+
29
ManagementConservative initial management• IV fluid resuscitation• Nasogastric (NG) tube: for abdominal decompression• IV antibiotics: patients receive broad-spectrum prophylactic antibiotics, often pre-operatively• Analgesia and anti-emetics
Surgical management• Emergency laparotomy to treat the underlying cause • Surgery is indicated in the following instances (bowel resection):
• Evidence of bowel ischaemia regardless of the cause• A non-adhesional cause (e.g. strangulated hernia)• Failure of conservative management for adhesional obstruction
• Adhesiolysis
30
A 60-year-old female presents to the emergency department with central abdominal pain,nausea and vomiting. The pain has been ‘coming and going’. She has had a previous openappendicectomy. Examination reveals central abdominal tenderness with ‘tinkling’ bowelsounds and abdominal distension. The rectum is empty.
ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8
Q1
The patient requires small bowel resection of a significant portion of bowel. Post-operatively, she is discharged and returns to clinic complaining of loose stools and crampy abdominal pain. What is the cause?
Case history
Recurrence of adhesional small bowel obstruction
Short gut syndrome
Dumping syndrome
Gastroenteritis
Achlorhydria
Q4Q3Q2
32
Complications
System Complication
Gastrointestinal • Bowel ischaemia and perforation
Infective • Sepsis• Aspiration pneumonia
Iatrogenic • Short-gut syndrome: if bowel has been resected, there is a risk of malabsorption
History and examinationA 70-year-old male presents to the emergencydepartment with generalised abdominal painand an inability to pass flatus or faeces for thepast 5 days.
He has a background of Parkinson’s disease andhypertension
ObservationsHR 120, BP 110/70, RR 17, SpO2 96%, Temp 37.5
33
Case-based discussion: 2
34
A 70-year-old male presents to the emergency department with generalisedabdominal pain and an inability to pass flatus or faeces for the past 5 days.
He has a background of Parkinson’s disease.
ObservationsHR 120, BP 110/70, RR 21, SpO2 96%, Temp 37.5
Q1 Q2
What is the most common cause of the underlying diagnosis?
Case history
Caecal volvulus
Bowel strictures
Colorectal cancer
Bowel adhesions
Toxic megacolon
app.bitemedicine.com
Q3
History and examinationA 70-year-old male presents to the emergencydepartment with generalised abdominal painand an inability to pass flatus or faeces for thepast 5 days.
He has a background of Parkinson’s disease andhypertension.
ObservationsHR 120, BP 110/70, RR 17, SpO2 96%, Temp 37.5
35
Case-based discussion: 2
Definition• Large bowel obstruction (LBO) occurs due to mechanical or functional obstruction of the large
intestine that prevents the normal passage of contents
Epidemiology and risk factors• Increasing age: usually in people over 65 years old
36
Introduction
37
The three most common causes
Causes Comments
Colorectal cancer The most common cause
Stricture A complication of diverticulitis, inflammatory bowel disease, or post-anastomosis
Volvulus Sigmoid or caecal
Definition• Large bowel obstruction (LBO) occurs due to mechanical or functional obstruction of the large
intestine that prevents the normal passage of contents
Epidemiology and risk factors• Increasing age: usually in people over 65 years old• Colorectal cancer: smoking, obesity, processed meat, IBD• Stricture: diverticulitis, IBD• Volvulus: chronic constipation, neuropsychiatric conditions (sigmoid), female (caecal)
38
Introduction
39
Linking pathophysiology and symptoms
© BiteMedicine 2020
40
Linking pathophysiology and symptoms
Less significant than in SBO
© BiteMedicine 2020
41
Clinical features
Symptoms Signs
Colicky, generalised abdominal pain Abdominal tenderness and distension
Bloating Tinkling bowel sounds
Absolute constipation: no passing of faeces of flatus
Rectal examination: empty rectum
Vomiting: may be faeculent; a LATE symptom in LBO
Tachycardia and hypotension
42
Differentials
CholecystitisUreteric colic
PyelonephritisHepatitis
Pneumonia
AppendicitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Ureteric colicPyelonephritis
Pneumonia
DiverticulitisUreteric colic
Inguinal herniaIBD
Testicular torsionGynaecological causes
UTI
Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction
Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm
43
What does the patient’s abdominal X-ray demonstrate?Q2Q1 Q3
44
InvestigationsPrimary investigations• Bloods:
• FBC: elevated white cell count with neutrophilia• U&Es: assess for pre-renal AKI• CRP: raised • Venous blood gas: to assess the degree of lactic/metabolic acidosis • Group and save: patients may require surgery
• Abdominal X-ray: first-line imaging• Dilated large bowel may be visible (> 6cm in the colon; > 9cm in the caecum)
• CT abdomen and pelvis with contrast: gold standard imaging
Investigations to consider• Erect chest X-ray: to assess for pneumoperitoneum if concerned about perforation• Contrast enema: a water-soluble contrast fluid can be used to identify obstruction if the above
investigations are equivocal
45
Management
+
46
A 70-year-old male presents to the emergency department with generalisedabdominal pain and an inability to pass flatus or faeces for the past 5 days.
He has a background of Parkinson’s disease.
ObservationsHR 120, BP 110/70, RR 21, SpO2 96%, Temp 37.5
Q2
CT demonstrates sigmoid volvulus. What is the most appropriate management?
Case history
Right hemicolectomy
Stenting
Hartmann’s procedure
Defunctioning colostomy
Rigid sigmoidoscopy and flatus tube insertion
app.bitemedicine.com
Q3Q1
48
Management
Conservative initial management• IV fluid resuscitation• Nasogastric (NG) tube: for abdominal decompression• IV antibiotics: patients usually receive prophylactic antibiotics due to the risk of bacterial
translocation • Analgesia and anti-emetics
Treat the cause• Colon cancer: stenting or surgical resection, e.g. Hartmann’s procedure• Rectal cancer: defunctioning colostomy• Diverticular disease: Hartmann’s procedure or resection, with or without a stoma• Sigmoid volvulus: rigid sigmoidoscopy with flatus tube insertion• Caecal volvulus: usually requires surgery; right hemicolectomy is often performed• Unclear cause: exploratory laparotomy
49
Complications and prognosis
System Complication
Gastrointestinal • Bowel ischaemia and perforation
Infective • Sepsis• Aspiration pneumonia
Covered today…• Small bowel obstruction• Large bowel obstruction
Next time…• Appendicitis• Perforated peptic ulcer• Diverticular bleeding• Ischaemic colitis / mesenteric ischaemia
50
Conditions to cover
53
References
1. Slides 6-10, 14, 21, 22, 36, 39, 46. Upper body front.png: Mikael HäggströmBackground made transparent by Frédéric MICHELforThis image was improved or created by the Wikigraphists of the Graphic Lab (fr). https://commons.wikimedia.org/wiki/File:Human_body_silhouette.svg
2. Slide 16. LadyofHats / Public domain. https://commons.wikimedia.org/wiki/File:Digestive_system_diagram_an.svg
3. Slide 23 and 24. James Heilman, MD / CC BY-SA (https://creativecommons.org/licenses/by-sa/3.0). https://commons.wikimedia.org/wiki/File:Upright_X-ray_demonstrating_small_bowel_obstruction.jpg
4. Slide 28. Hellerhoff / CC BY-SA (https://creativecommons.org/licenses/by-sa/3.0). https://commons.wikimedia.org/wiki/File:Pneumatosis_intestinalis_CT_LF_Darmischaemie.jpg
5. Slide 47. Hellerhoff / CC BY-SA (https://creativecommons.org/licenses/by-sa/3.0). https://commons.wikimedia.org/wiki/File:Sigmavolvulus_-_Coffee-bean-sign_-_LSL.jpg
54
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