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BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

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Page 1: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide
Page 2: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

• Q&A with Mr Tomasi

• Cover two key general surgical emergencies

• Provide important differential diagnoses

• Pathophysiology, clinical features, investigations, management, prognosis

• Multi-step SBAs: for a full understanding of the patient journey

• Summary and Q&A

2

Aims and objectives

Page 3: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

Introducing our special guest

3

Page 4: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide
Page 5: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

Covered today…• Small bowel obstruction• Large bowel obstruction

Next time…• Appendicitis• Perforated peptic ulcer• Diverticulitis / diverticular bleeding• Ischaemic colitis and mesenteric ischaemia

5

Conditions to cover

Page 6: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

6

Overview

CholecystitisUreteric colic

PyelonephritisHepatitis

Pneumonia

AppendicitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Ureteric colicPyelonephritis

Pneumonia

DiverticulitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction

Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm

© BiteMedicine 2020

Page 7: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

7

Overview

CholecystitisUreteric colic

PyelonephritisHepatitis

Pneumonia

AppendicitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Ureteric colicPyelonephritis

Pneumonia

DiverticulitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction

Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm

© BiteMedicine 2020

Page 8: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

8

Overview

CholecystitisUreteric colic

PyelonephritisHepatitis

Pneumonia

AppendicitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Ureteric colicPyelonephritis

Pneumonia

DiverticulitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction

Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm

© BiteMedicine 2020

Page 9: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

9

Overview

CholecystitisUreteric colic

PyelonephritisHepatitis

Pneumonia

AppendicitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Ureteric colicPyelonephritis

Pneumonia

DiverticulitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction

Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm

© BiteMedicine 2020

Page 10: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

History and examinationA 60-year-old female presents to the emergencydepartment with central abdominal pain,nausea and vomiting. The pain has been‘coming and going’.

She has had a previous open appendicectomy.

Examination reveals central abdominaltenderness with ‘tinkling’ bowel sounds andabdominal distension. The rectum is empty.

ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8

10

Case-based discussion: 1

Page 11: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

11

A 60-year-old female presents to the emergency department with central abdominalpain, nausea and vomiting. The pain has been ‘coming and going’. She has had aprevious open appendicectomy. Examination reveals central abdominal tendernesswith ‘tinkling’ bowel sounds and abdominal distension. The rectum is empty.

ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8

Q1 Q2

What is the most common cause of the underlying diagnosis?

Case history

Volvulus

Incarcerated hernia

Colorectal cancer

Bowel adhesions

Crohn’s disease

app.bitemedicine.com

Q3 Q4

Page 12: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide
Page 13: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

History and examinationA 60-year-old female presents to the emergencydepartment with central abdominal pain,nausea and vomiting. The pain has been‘coming and going’.

She has had a previous open appendicectomy.

Examination reveals central abdominaltenderness with ‘tinkling’ bowel sounds andabdominal distension. The rectum is empty.

ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8

13

Case-based discussion: 2

Page 14: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

Definition• Small bowel obstruction (SBO) is a mechanical or functional obstruction of the small intestine that

prevents the normal passage of digestive contents

Epidemiology and risk factors• Rare in those without previous surgery (‘virgin’ abdomen)• Previous surgery increases risk by 12-fold• Average age is 60-years-old

14

Introduction

Page 15: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

15

Very basic anatomy

Page 16: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

16

Important causes

Causes Comments

Bowel adhesions: the most common cause Due to previous abdominal surgery

Incarcerated hernia Usually femoral or inguinal

Crohn’s disease Due to stricture formation

Volvulus Commonly causes large bowel obstruction

Intussusception More common in children

Paralytic ileus Functional obstruction due to failure of peristalsis

Page 17: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

17

Important causes

Causes

Bowel adhesions: the most common cause

Incarcerated hernia

Crohn’s disease

Volvulus

Intussusception

Paralytic ileus

Page 18: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

18

Linking pathophysiology and symptoms

© BiteMedicine 2020

Page 19: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

19

Clinical features

Symptoms Signs

Colicky, central or generalised abdominal pain Abdominal tenderness and distension

Nausea and vomiting: an EARLY symptom in SBO

Tinkling bowel sounds

Bloating Rectal examination: rectum may be empty• Blood suggests strangulation and ischaemia

Absolute constipation: a LATE symptom in SBO Tachycardia and hypotension

Page 20: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

20

Differentials

CholecystitisUreteric colic

PyelonephritisHepatitis

Pneumonia

AppendicitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Ureteric colicPyelonephritis

Pneumonia

DiverticulitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction

Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm

© BiteMedicine 2020

Page 21: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

History and examinationA 60-year-old female presents to the emergencydepartment with central abdominal pain,nausea and vomiting. The pain has been‘coming and going’.

She has had a previous open appendicectomy.

Examination reveals central abdominaltenderness with ‘tinkling’ bowel sounds andabdominal distension. The rectum is empty.

ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8

21

Case-based discussion: 1

Page 22: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

22

An abdominal X-ray is performed…

Page 23: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

23

A 60-year-old female presents to the emergency department with central abdominalpain, nausea and vomiting. The pain has been ‘coming and going’. She has had aprevious open appendicectomy. Examination reveals central abdominal tendernesswith ‘tinkling’ bowel sounds and abdominal distension. The rectum is empty.

ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8

Q2Q1

What bowel diameter suggests small bowel dilatation on imaging?

Case history

> 6 cm

> 1 cm

> 3 cm

> 9 cm

> 12 cm

app.bitemedicine.com

Q3 Q4

Page 24: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide
Page 25: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

25

Investigations

Primary investigations• Bloods:

• FBC: elevated white cell count with neutrophilia• U&Es: pre-renal AKI and assess for electrolyte imbalances (paralytic ileus)• CRP: usually raised• Group and save: patients may require surgery• VBG: to assess the degree of lactic/metabolic acidosis (suggests ischaemia)• Abdominal X-ray: first-line imaging; dilated small bowel loops (>3cm) with fluid levels

• CT abdomen and pelvis with contrast: gold standard imaging

Investigations to consider• Erect chest X-ray: to assess for pneumoperitoneum if concerned about perforation• Contrast studies: the patient can drink water-soluble contrast (e.g. gastrograffin) and have serial X-

rays; if the contrast fails to reach the colon this is an indication for surgery

Page 26: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

26

What does the patient’s CT scan demonstrate?Q3

Page 27: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

27

Management

“Never let the sun rise or set on small-bowel obstruction”

Page 28: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

28

Management

+

Page 29: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

29

ManagementConservative initial management• IV fluid resuscitation• Nasogastric (NG) tube: for abdominal decompression• IV antibiotics: patients receive broad-spectrum prophylactic antibiotics, often pre-operatively• Analgesia and anti-emetics

Surgical management• Emergency laparotomy to treat the underlying cause • Surgery is indicated in the following instances (bowel resection):

• Evidence of bowel ischaemia regardless of the cause• A non-adhesional cause (e.g. strangulated hernia)• Failure of conservative management for adhesional obstruction

• Adhesiolysis

Page 30: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

30

A 60-year-old female presents to the emergency department with central abdominal pain,nausea and vomiting. The pain has been ‘coming and going’. She has had a previous openappendicectomy. Examination reveals central abdominal tenderness with ‘tinkling’ bowelsounds and abdominal distension. The rectum is empty.

ObservationsHR 130, BP 100/70, RR 20, SpO2 95%, Temp 37.8

Q1

The patient requires small bowel resection of a significant portion of bowel. Post-operatively, she is discharged and returns to clinic complaining of loose stools and crampy abdominal pain. What is the cause?

Case history

Recurrence of adhesional small bowel obstruction

Short gut syndrome

Dumping syndrome

Gastroenteritis

Achlorhydria

Q4Q3Q2

Page 31: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide
Page 32: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

32

Complications

System Complication

Gastrointestinal • Bowel ischaemia and perforation

Infective • Sepsis• Aspiration pneumonia

Iatrogenic • Short-gut syndrome: if bowel has been resected, there is a risk of malabsorption

Page 33: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

History and examinationA 70-year-old male presents to the emergencydepartment with generalised abdominal painand an inability to pass flatus or faeces for thepast 5 days.

He has a background of Parkinson’s disease andhypertension

ObservationsHR 120, BP 110/70, RR 17, SpO2 96%, Temp 37.5

33

Case-based discussion: 2

Page 34: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

34

A 70-year-old male presents to the emergency department with generalisedabdominal pain and an inability to pass flatus or faeces for the past 5 days.

He has a background of Parkinson’s disease.

ObservationsHR 120, BP 110/70, RR 21, SpO2 96%, Temp 37.5

Q1 Q2

What is the most common cause of the underlying diagnosis?

Case history

Caecal volvulus

Bowel strictures

Colorectal cancer

Bowel adhesions

Toxic megacolon

app.bitemedicine.com

Q3

Page 35: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

History and examinationA 70-year-old male presents to the emergencydepartment with generalised abdominal painand an inability to pass flatus or faeces for thepast 5 days.

He has a background of Parkinson’s disease andhypertension.

ObservationsHR 120, BP 110/70, RR 17, SpO2 96%, Temp 37.5

35

Case-based discussion: 2

Page 36: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

Definition• Large bowel obstruction (LBO) occurs due to mechanical or functional obstruction of the large

intestine that prevents the normal passage of contents

Epidemiology and risk factors• Increasing age: usually in people over 65 years old

36

Introduction

Page 37: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

37

The three most common causes

Causes Comments

Colorectal cancer The most common cause

Stricture A complication of diverticulitis, inflammatory bowel disease, or post-anastomosis

Volvulus Sigmoid or caecal

Page 38: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

Definition• Large bowel obstruction (LBO) occurs due to mechanical or functional obstruction of the large

intestine that prevents the normal passage of contents

Epidemiology and risk factors• Increasing age: usually in people over 65 years old• Colorectal cancer: smoking, obesity, processed meat, IBD• Stricture: diverticulitis, IBD• Volvulus: chronic constipation, neuropsychiatric conditions (sigmoid), female (caecal)

38

Introduction

Page 39: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

39

Linking pathophysiology and symptoms

© BiteMedicine 2020

Page 40: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

40

Linking pathophysiology and symptoms

Less significant than in SBO

© BiteMedicine 2020

Page 41: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

41

Clinical features

Symptoms Signs

Colicky, generalised abdominal pain Abdominal tenderness and distension

Bloating Tinkling bowel sounds

Absolute constipation: no passing of faeces of flatus

Rectal examination: empty rectum

Vomiting: may be faeculent; a LATE symptom in LBO

Tachycardia and hypotension

Page 42: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

42

Differentials

CholecystitisUreteric colic

PyelonephritisHepatitis

Pneumonia

AppendicitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Ureteric colicPyelonephritis

Pneumonia

DiverticulitisUreteric colic

Inguinal herniaIBD

Testicular torsionGynaecological causes

UTI

Epigastric region• Peptic ulcer disease• Pancreatitis• Cholecystitis• Myocardial infarction

Periumbilical region• Appendicitis• Small bowel obstruction• Large bowel obstruction• Abdominal aortic aneurysm

Page 43: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

43

What does the patient’s abdominal X-ray demonstrate?Q2Q1 Q3

Page 44: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

44

InvestigationsPrimary investigations• Bloods:

• FBC: elevated white cell count with neutrophilia• U&Es: assess for pre-renal AKI• CRP: raised • Venous blood gas: to assess the degree of lactic/metabolic acidosis • Group and save: patients may require surgery

• Abdominal X-ray: first-line imaging• Dilated large bowel may be visible (> 6cm in the colon; > 9cm in the caecum)

• CT abdomen and pelvis with contrast: gold standard imaging

Investigations to consider• Erect chest X-ray: to assess for pneumoperitoneum if concerned about perforation• Contrast enema: a water-soluble contrast fluid can be used to identify obstruction if the above

investigations are equivocal

Page 45: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

45

Management

+

Page 46: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

46

A 70-year-old male presents to the emergency department with generalisedabdominal pain and an inability to pass flatus or faeces for the past 5 days.

He has a background of Parkinson’s disease.

ObservationsHR 120, BP 110/70, RR 21, SpO2 96%, Temp 37.5

Q2

CT demonstrates sigmoid volvulus. What is the most appropriate management?

Case history

Right hemicolectomy

Stenting

Hartmann’s procedure

Defunctioning colostomy

Rigid sigmoidoscopy and flatus tube insertion

app.bitemedicine.com

Q3Q1

Page 47: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide
Page 48: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

48

Management

Conservative initial management• IV fluid resuscitation• Nasogastric (NG) tube: for abdominal decompression• IV antibiotics: patients usually receive prophylactic antibiotics due to the risk of bacterial

translocation • Analgesia and anti-emetics

Treat the cause• Colon cancer: stenting or surgical resection, e.g. Hartmann’s procedure• Rectal cancer: defunctioning colostomy• Diverticular disease: Hartmann’s procedure or resection, with or without a stoma• Sigmoid volvulus: rigid sigmoidoscopy with flatus tube insertion• Caecal volvulus: usually requires surgery; right hemicolectomy is often performed• Unclear cause: exploratory laparotomy

Page 49: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

49

Complications and prognosis

System Complication

Gastrointestinal • Bowel ischaemia and perforation

Infective • Sepsis• Aspiration pneumonia

Page 50: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

Covered today…• Small bowel obstruction• Large bowel obstruction

Next time…• Appendicitis• Perforated peptic ulcer• Diverticular bleeding• Ischaemic colitis / mesenteric ischaemia

50

Conditions to cover

Page 51: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide
Page 52: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide
Page 53: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

53

References

1. Slides 6-10, 14, 21, 22, 36, 39, 46. Upper body front.png: Mikael HäggströmBackground made transparent by Frédéric MICHELforThis image was improved or created by the Wikigraphists of the Graphic Lab (fr). https://commons.wikimedia.org/wiki/File:Human_body_silhouette.svg

2. Slide 16. LadyofHats / Public domain. https://commons.wikimedia.org/wiki/File:Digestive_system_diagram_an.svg

3. Slide 23 and 24. James Heilman, MD / CC BY-SA (https://creativecommons.org/licenses/by-sa/3.0). https://commons.wikimedia.org/wiki/File:Upright_X-ray_demonstrating_small_bowel_obstruction.jpg

4. Slide 28. Hellerhoff / CC BY-SA (https://creativecommons.org/licenses/by-sa/3.0). https://commons.wikimedia.org/wiki/File:Pneumatosis_intestinalis_CT_LF_Darmischaemie.jpg

5. Slide 47. Hellerhoff / CC BY-SA (https://creativecommons.org/licenses/by-sa/3.0). https://commons.wikimedia.org/wiki/File:Sigmavolvulus_-_Coffee-bean-sign_-_LSL.jpg

Page 54: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

54

Further information

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Want to get involved? Contact us at [email protected] to receive your information pack.

Stay up-to-date!• Website: www.bitemedicine.com• Facebook: www.facebook.com/biteemedicine• Instagram: @bitemedicine• Email: [email protected]

Page 55: BiteMedicine - Lecture 36 (General Surgical Emergencies) Slide

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