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diagnosis between physiogenic and psychogenic cases,would however, Group Captain Symonds pointed out, beunprofitable. Dr. Aubrey Lewis spoke in detail aboutthis problem. It is not possible by psychological teststo recognise with certainty physiogenic disturbances offunction, except when the structural damage is gross orlocalised. The same difficulty about criteria prevailswhen other methods of differentiation are tried. Suchtests do not make allowance for the large part played byindividual and social factors in the causation of the post-contusional syndrome. A comparison was made betweena group of men with this syndrome and an equal numberof patients in a neurosis centre who had not had any headinjury. The similarities between the two groups were
striking and the significant differences few : the patientswith postcontusional syndrome who are referred to aneurosis centre are much the same sort of people, andcall for much the same sort of treatment, as the " non-organic " group. Moreover, among those who sustainhead injury on the roads there will be a higher thanaverage proportion of "
accident-prone " persons whoare perhaps psychopathic and predisposed to neuroticbehaviour. The most potent causes of the postcon-tusional syndrome may be found in the situation arisingout of the accident. It is not only compensation andother crude advantage that needs consideration, importantthough it is. Insecurity, loss of employment, and similarsocial factors operate, as well as the hypochondriacal,anxious, depressive and other latent trends mademanifest and active by the threat to life, reason orhealth to which the patient believes he has been exposed.Both the speakers stressed the value of occupational andpsychological treatment in the prevention and manage-ment of these cases. Group Captain Symonds held thatthe assessment of prognosis as early as possible, and itsinterpretation to the patient, were most important sincemany of the patient’s symptoms depend on his uncer-tainty and fears about what the future holds in store forhim. Dr. Lewis insisted also on the harm done by needlessrepetition of special investigations, and on the carethat should be given to the patient’s social and individualproblems if the well-ordered programme of rehabilitationis to achieve its aim of restoring him to health andworking capacity.
OVERACTIVE CHILDREN IN THE MAKING
THE child who is " never still for an instant " canexhaust his family without seeming to broach his ownreserves. All healthy children are active, but in somethis characteristic is exaggerated and coupled with otherqualities even harder to manage. Russell,l reviewingthe causes of hyperactivity, reminds us that the basis issometimes organic, and that it is not always easy todistinguish such cases. Overactive children are
described as restless, wild, impulsive, nervous or fidgety;they are often aggressive and mischievous, and mayhave brought their parents to such a pitch of morbidexpectancy that all parties are on tenterhooks, the childskirmishing to outwit the parents and the parentsmanoeuvring to circumvent the child. By the time he isbrought to the clinic this preoccupation has led to other.complaints-his school work has suffered, he can’t learnto read, he is always fighting, he doesn’t mind whatanybody says to him, he can’t fit in with his school-fellows. The parents, willing enough at first to believethat he is not vicious but merely exhausting, come intime to believe that he is incorrigible. Russell regardshyperactivity as having many components. Childrenwho become restless and impulsive after an attack ofencephalitis lethargica are well known in colonies ofmental- defectives ; in such cases the cerebral damageis’ in and about the basal ganglia, and probably birthinjury or the infections of childhood sometimes damagethe same region. Electroencephalographv has made it
1. Russell, J. A. Amer. J. Dis. Child. 1942, 63, 94.
possible tb demonstrate physiological disturbances inthe brains of some children whose behaviour disorderswould otherwise have been called purely psychogenic.He suggests that the possibility of an organic basis shouldbe considered whenever there is a combination of over-
activity, significant history, poor coordination, tremors,athetoid movements, urge to talk with propulsivespeech, too brisk reflexes, polyuria, palsy residuals, orsigns of endocrine disturbance. Organic signs, however,may be entirely lacking, and the only pointer may thenbe a history of a change in development or behaviourafter a head injury or an infectious illness-a change,that is to say, out of proportion to all factors in theenvironment or emotional life. Children with such an
organic basis of their behaviour problem are likely to bemismanaged because their parents, unaware of any reasonfor leniency, treat them too strictly. On the other hand,organic damage can be used as a too-handy explanationof undesirable behaviour, and may lead to a defeatistattitude in treatment. Russell points out that only avery small proportion of children have significant cerebralchanges after infections or head injuries, that environ-ment matters as much for a child with an organiclesion as for one with an emotional problem, andthat in the management of either adjustment of thehome situation plays an important part. He quotesthe finding of Childers that the home of the overactivechild is usually disordered and chaotic. Exposed toconstant nagging, the child feels unwanted and insecure.At school he is too easily distracted, and too impulsiveto play well with others ; he tries to get attention,seeks friends but cannot make them, and is regarded’ asa nuisance. The main object of treatment must be-inthe organic as well as the emotional case-to relieve theunfavourable tension between him and his parents.
BLOOD-PRESSURE READINGSTHE variable factors responsible for the level of the
peripheral arterial blood-pressure at any one momentare notoriously many, some can be standardised-forexample, the effects of exercise, emotion, and pain, theposition of the patient, and the accurate levelling of thesphygmomanometer in relation to the heart-but thecorrelation between the reading obtained and the actualintra-arterial pressure is still not very close. TheCardiac Society in this country, in collaboration with theAmerican Heart Association, produced a useful memor-andum 1 which has done much to standardise technique ;but it is still unjustifiable to record pressure except tothe nearest 5 mm.-there can be no significant clinicaldifference between a reading of say 123/78 and 125/80mm. Hg. Using as their standard an optical mano-meter to record intra-arterial pressure, Ragan andBordley 2 have investigated the accuracy of blood-
pressure readings obtained by the usual cuff method in51 relatively young adults. They found that thesystolic pressure as recorded by the usual clinical methodwas affected by both size of arm and the contour of thepulse wave ; in patients with small arms the ausculta-tory readings are usually too low, while in those withlarge arms they are usually too high. Occasionallyauscultatory readings are 30 mm. Hg different from thoseobtained by the intra-arterial method, but excludingthose with arms greater than 35 cm. or less than 24 cm.in circumference and those with aortic incompetence theauscultatory systolic readings came within 10 mm. Hgof the intra-arterial pressure in 83% of cases. Thediastolic pressure recorded by the auscultatory methodwas usually higher than the intra-arterial measurement,the difference increasing with increasing size of the arm.In accordance with general clinical experience the
auscultatory diastolic pressure recorded was much toolow in most cases of aortic incompetence. Excluding1. Brit. Heart J. 1939, 1, 261.2. Ragan, C. and Bordley, J. Bull. Johns Hopk. Hosp. 1941, 79, 504.
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these cases the mean auscultatory reading was’8 mm. Hghigher than the intra-arterial. Varying the width of thecuff from the standard 13 cm. to 20 cm. improved theaccuracy of both the systolic and diastolic readings insome obese subjects ; but in most subjects, particularlythose with thin arms, the wide cuff yielded readingswhich were too low. Though their numbers are rather’few, these workers produce figures which suggest thatin people with large arms (circumference 30-42-5 cm.)the auscultatory estimate of diastolic pressure becomesan additional 3 mm. Hg too high for each 1 cm. increasein the circumference of the arm above 30 cm. They saythat the sudden fading of the sounds is a more reliableguide to’ the diastolic pressure than their complete dis-appearance. These findings remind us that clinicalreadings of blood-pressure are merely approximate,though if recorded carefully they provide a useful guideto diagnosis and prognosis. It is clear that in plumpsubjects a wide cuff should be used before any opinionis given about a slight degree of hypertension.
RADIOTHERAPY OF CANCER
WITHIN the last few years two advances in radiologyhave revolutionised its value as a therapeutic agent.First, we can now control with exactitude the surfacedoses of X ory rays; secondly, it is possible to estimatethe distribution through the living tissues of radiationsat various distances and in different directions from the
place of their application, so that the dosage throughoutthe irradiated parts can be regulated with a high degreeof accuracy. - The calculation required before applyingdeep therapy, whether by X or y rays, needs a speciallytrained physicist who may or may not be the radiologisthimself. For the moment the facilities for using thelatest knowledge in this department of medicine are notwidespread, and there are formidable obstacles to theirextension. Among these obstacles are the difficultieswhich beset the specialist in radiology. To acquire theknowledge necessary to practise this particular kind ofwork is a task arduous enough to discourage any but themost determined aspirant, and when he has overcomeevery intermediate obstruction and gained his diplomahe finds that he cannot freely practise what he professes.Radiotherapy, being a relatively new form of specialism,is not allotted beds in most hospitals. Cases submitted tothe radiotherapist for treatment are not as a rule of hisown selection, but are filtered through the hands of thehonorary staff in whose wards they are kept and underwhose care they nominally remain. These disadvantageshave had to be faced by every new branch of medicalspecialism in turn and must be attributed to humannature, but they have been and will be overcome. Itwould be a pity, however, if the usual road is followedin this instance. The denial of hospital beds to specialistsin the past led to the establishment of a number ofindependent special hospitals, with detrimental effectson the medical schools. There is much to be said for
making a fully equipped radiotherapeutical departmentan integral part of every teaching hospital, with officersin charge whose status and voting powers are equal tothose of any other member of the visiting staff. To sucha vision there is yet another obstacle-the expense. Butthe war with its necessities has taught us to revise ournotions of this barrier.
SULPHATHIAZOLE OINTMENT IN IMPETIGO
WORK on the use of the sulphonamides and theirderivatives locally in skin and wound infections has
naturally suggested their use in impetigo contagiosa.This in its turn has raised the old question whetherimpetigo is streptococcal or staphylococcal in origin.The prevailing view is that it may be either, with the, added factor that some streptococcal cases may becomesecondarily infected with staphylococci, though a year
ago, R. E. Hope Simpsonl put forward a strong case for aspecific "inpetigococcus." A. J. Steigman2 examined25 cases of impetigo bacteriologically and found haemolyticstreptococci in 12 cases, Staphylococcus aureus in 8cases and a combination of both in 5 cases. Thisprompted him to try 5% sulphathiazole in an ointmentbase and he found that healing took place in about 4days compared with an average of 8 days required toobtain a cure when ammoniated mercury ointment wasused. L. H. Winer and E. A. Strakosch3 treated 60cases of impetigo with 5% sulphathiazole in cod-liver oilointment and obtained a cure in an average of just over4 days. They selected cod-liver oil ointment as a basebecause it was an easy medium to use and it did notdiminish the activity of the drug. They also treated20 patients with sulphathiazole by the mouth and nolocal treatment and obtained cures in an average of 92days. Pillsbury and others4 went further and treated avariety of infectious dermatoses with sulphathiazole, andalthough some of their results in other conditions weregood the cases of impetigo responded far and away thebest. They thought that an oil-in-water emulsion wasthe best base but obtained good results with an ointment.All these observers urge the importance of frequent andthorough removal of crusts and scales before applying theointment, and favour application 4-6 times a day. It
appears then that a 5% sulphathiazole ointment willcure impetigo in 4 or 5 days. This is a real advance on
any previous method of treatment, and in so infectious adisease a reduced period of infectivity should lessen thenumber of contact cases. Judging by the results so farpublished there is no object in giving the drug by mouth.
Mr. A. SEYMOUR HARDING, F.S.S., has retired fromthe general secretaryship of the Royal Institute ofPublic Health and Hygiene on -account of ill health.He had completed 30 years of service with the presentinstitute and with the former Institute of Hygiene, andthe good wishes of the whole fellowship go with him.THE death is announced from Lucerne of Dr. EDWARD
NEUMANN who was associated with Dr. Lucius Spenglerin the foundation of the Schatzalp, a luxury sanatoriumhigh up above Davos-Platz. Neumann as resident hadall the burden of administration, which was very welldone, but he was also an essential partner in the earlywork on pneumothorax, for which Brauer paid occasionalvisits from Hamburg. As a guide and friend Neumannis still gratefully remembered by British and Americanex-patients.THE Minister of Health and the Secretary of State for
Scotland have appointed a committee " to inquire intothe organisation of medical schools, particularly in
regard to facilities for clinical teaching and researchand to make recommendations." The following haveaccepted invitations to serve : Mr. W. M. Goodenough(chairman), Prof. T. R. Elliott, M.D., F.R.S., Dr. A.M. H.Gray, Prof. James Hendry,CF.R.C.O.G., Prof. A. V. Hill,F.R.B., Sir Wilson Jameson, M.D., Prof. J. R. Lear-month, F.R.C.S.E., Sir Ernest Pooley, Sir John Stopford,M.D., F.R.S., and Dr. Janet Vaughan.1. Lancet, 1941, i, 683. 2. Brit. med. J. 1942, i, 12.3. J. Amer. med Ass. 1942, 118, 221.4. Pillsbury, D. M., Wammock, V. S., Livingood, C. S. and Nichols,
A. C. Amer. J. med. Sci. 1941, 202, 808.
ROYAL COLLEGE OF OBSTETRICIANS AND GYNaeCOLOGISTS.-After July candidates for the membership of the collegemay not proceed to the examination till their case-recordsand commentaries have been accepted by the examinationcommittee. At present the case-records are submitted aspart of the examination, but after July they must be pre-sented not less than nine weeks before the examination.Candidates not attending for examination within three yearsof acceptance of their case-records will be required to presenta new set. Further particulars may be had from the secretaryof the college, 58, Queen Anne Street, London, W.1.