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BMT 2012 Clinical CT Applications

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    Wim Tukker systeemspecialist CT UMCG

    Imaging Techniques in Radiology: CT

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    Ch 13. Computed Tomography13.1 Explain basic principles13.2 Explain geometry and historical development13.3 Understand detectors and detector arrays13.4 Explain slice thickness, pitch

    13.5 Explain tomographic reconstruction process13.6 Understand digital image display13.9 Explain artifacts

    End terms for Imaging Techniques in Radiology

    Following the book The Essential Physics of Medical Imaging 2nd ed byBushberg et al.

    Know -> Understand -> Explain(Read), (optional)

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    What to expect?

    - CT in Archeology

    - CT in Cardiology

    - Clinical CT applications: head and neck

    - CT Techniques

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Monday26 march 2012

    09.00 12.00 h

    Thursday29 march 2012

    13.00 16.00 h

    - Dual Energy CT

    - CT Techniques

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    What to expect?

    - CT in Archeology

    - CT in Cardiology

    - Clinical CT applications: head and neck

    - CT Techniques

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Monday26 march 2012

    09.00 12.00 h

    Thursday29 march 2012

    13.00 16.00 h

    - Dual Energy CT

    - CT Techniques

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    Siemens Somatom Sensation-16 Siemens Somatom Sensation-64 (2x) Siemens Somatom Definition (Dual Source)

    CTs in UMCG: Radiology, Nucleair Medicine & Radiotherapie

    Siemens Biograph 64 slice mCT (PET-CT) Siemens Symbia 2 and 16 slice SPECT-CT Siemens Sensation Open

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    Toshiba

    AquilionONE

    Brilliance iCTPhilips

    SiemensDualSource Defini

    tionG.E.

    CT750HD

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    Conventional tube diagram

    Straton X-ray tube diagram(Sensation 64 and Definition)

    Cooling rate 5 MHU/min

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    Double z-Sampling: two focus spots alternating 4.640 per second

    Straton X-ray tube design

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    0.4 x 0.4 x 0.4 mm isotropic resolutionDouble z-Sampling:

    Sensation 64, Definition

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    Adaptive Array Detectors

    Thin collimation platesCeramic scintillationmaterial (solide state detector)Very short after glowing time (gadolinium oxi-sulfide) < 0,00043 sec!Photodiode-array

    Configuration detector system Sensation 64 and Definition (A-tube)

    4x1.2mm

    32x0.6mm

    4x1.2mm

    24x1.2 >

    28.8mmZco

    verage

    CT technique

    page 339 - 342Bushberg,

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    Sensation 16

    24 rows of detectors16.128 elements1.344 canals per slice

    Max. 2320 projections each 360

    Sensation 64 and Dual Source

    40 rows of detectors (DSCT 2x, A and B)26.880 elements (DSCT system B 14.080)

    21.504 canals per slice (DSCT system B 11.264)Max. 4608 projections (views) each 360

    Configuration detector system Sensation 64 and Definition (A-tube)

    CT technique

    page 339 - 342Bushberg,

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    Sensation-16: 24 detectors on row!

    8 x 2.7 mm + 16 x 1.35 mm: true detectorwidth!

    eff. slice-thickness

    Collimation: principle

    page 339 - 342Bushberg,

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    Pitch: table feed per rotation / total width of collimated beam

    E.g. table feed 12 mm, collimation 16 x 0.75 > beam pitch 1

    Table feed: per rotation

    E.g. table feed 9.6 mm/rotation, collimation 64 X 0.6 (32 x 0.6=19.2 mm) > pitch 0.5

    Pitch en Table Feed

    Effective mAs

    mA.s produkt remains equal.

    E.g. Increasing pitch > shorter scantime > more mA.

    E.g. Decreasing rotationtime > longer total scantime > less mA.

    page 345 - 346Bushberg,

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    Is there influence of the pitch on the slice

    thickness?

    Is there any influence of the pitch on the spatialresolution?

    Pitch

    Effective mAs (radiationdose) stays equal.

    page 345 - 346Bushberg,

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    What to expect?

    - CT in Archeology

    - CT in Cardiology

    - Clinical CT applications: head and neck

    - CT Techniques

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Monday26 march 201209.00 12.00 h

    Thursday29 march 2012

    13.00 16.00 h

    - Dual Energy CT

    - CT Techniques

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    Guidelines for radiology report

    Increased brain pressure? Brain shifting?

    Bleeding? Differences in density? Abnormalities: localisation, size and number? Fractures? Bone destruction?

    Protocol CT-scan Brain

    Indications

    Standard

    Trauma Tumor or abces (MRI preferred) Metastases (MRI preferred) Stereolithography Navigation (stereotaxie)Radiation-dose 1.1 mSv

    CT-scan Brain

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    CT-scan Brain sequential or spiral?

    OMAxial view in spiral CT(source images)

    MPR in OM-direction(Orbito-Meatal)

    MPR; Multi PlanarReconstruction

    page 359 - 360Bushberg,

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    X-Y: 5 mm/index 5 mm

    (sequential)

    Z: 5 mm/index 5 mm

    CT-scan Brain sequential or spiral?

    Z: 3 mm/index 1.5 mmpage 371 - 372

    Partial Volume Effect

    Bushberg,

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    ICH

    IntraCranial

    Hematoma

    3D

    CT-scan Brain, examples

    Stroke!

    Most common question:

    Bleeding or no-bleeding?

    No-bleeding > start

    - Anti-thrombolytic drugs- Antiplatelet medicine like

    Aspirin

    ?

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    CT withIV-contrast:

    100 mlVisipaque 320

    Abces

    MRI-FLAIR MRI-T2MRI-T1 MRI-T1 + gado

    CT-scan Brain, examples

    ?

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    Vasculitis (inflammation)?

    white and grey matter

    oedema

    Same patient: possible cause of the abces?

    CT-scan Brain, examples

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    MPR Transversal MPR Coronal

    Transversal Coronal

    Spiral CT of maxillary sinus (NBH)

    Radiation-dose 0.2 mSv

    page 359 - 360Bushberg,

    MPR

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    Spiral CT of maxillary sinus (NBH)

    MPRThickening of mucus

    page 359 - 360Bushberg,

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    B-cell lymphomaAdvantage CT: superior bone/air visibility, why?

    Spiral CT of maxillary sinus (NBH)

    MPR

    page 359 - 360Bushberg,

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    Advantage MRI: superior soft tissue visibility

    Same patient, MRI

    Spiral CT of maxillary sinus (NBH)

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    Coronal

    Coronal

    CoronalCoronal

    Axial

    On a sagital imageMPR // canalis facialis

    Spiral CT of petrosal bone (mastoid)

    MPR perpendicularto canalis facialis

    Radiation-dose 0.3 mSv

    page 359 - 360Bushberg,

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    Anatomy

    Axial (transversal)

    Spiral CT of petrosal bone (mastoid)

    page 359 - 360Bushberg,

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    DSA versus CT (coronal MIP)

    Golden standard

    ?

    S i l CT f b i t i (CTA)

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    Spiral CT of brain arteries (CTA)

    Radiation-dose 1.2 mSv

    I.V. contrast: Visipaque 320; 80 ml with flow 4 ml/sec.

    Start scan manually!

    1 3

    4 5

    2

    6

    Spiral CT of brain arteries (CTA)

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    Scan in 10 15 sec.

    Advantages CTA: Non-invasive, short scanning time with onlimited 3D processing.

    Spiral CT of brain arteries (CTA)

    page 361Bushberg,

    Spiral CT of brain arteries (CTA)

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    Candidate for coiling procedure?

    Top of basilar arterie

    Spiral CT of brain arteries (CTA)

    page 361Bushberg,

    One Stop Diagnose CVA

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    One-Stop Diagnose CVA

    ?

    Unwell with left hemiparesis: infarction right hemisphere?

    Entrance

    One-Stop Diagnosis CVA

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    CTA VRT Day 3 Day 30CTA MIP

    Perfusion-CT

    Entrance

    One-Stop Diagnosis CVA

    Unwell with left hemiparesis: infarction right hemisphere?

    Traumatology

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    Technique: VRTHit by a baseball pole-axe

    Traumatology

    Bushberg, page 360-362

    T itiTraumatology

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    Trauma capitis

    SSD

    VRT

    Traumatology

    ?

    Bushberg, page 360-362

    (s ti t)Traumatology

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    (same patient)Traumatology

    Take Home Message: always start with looking at source images (first reconstruction)

    Bushberg, page 360-362

    Traumatology

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    More metal artefacts

    um gy

    Traumatology

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    By courtesy of Dr. J. Wildberger and Dr. A. Mahnken, University of Aachen

    Future: further reduction of metal artefacts

    gy

    Traumatology

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    Movement artefacts

    gy

    ?

    Traumatology

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    Gunshot

    ?

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    Protocol CT-scan Neck

    Indications

    Standard Oncology

    Trauma CTA

    (Hernia to MRI)

    Guidelines for radiology report

    Soft tissue evaluation. Pathology?

    Nodules, glands? CTA: stenosis? CTA: aneurysm? Fractures? Bone destruction?

    Radiation-dose 1.1 mSv

    CT neck with contrast

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    Maligne lymfoma with necrotic lymph gland.

    Hindering metal artefacts

    Future: Iterative reconstruction, less artefacts and lower dose!

    Partial Volume effect

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    Enlarged thyroid: problems with swallow

    MPR coronal direction: 1, 3 - 5 mm slice thickness

    Partial Volume effect: sharp versus unsharp, noisy versus a better S/N ratio

    MPR 1 mm MPR 3 mm MPR 5 mm

    Bushberg, page 371-372

    Traumatology

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    Wear, (slijtage)

    Traumatology

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    Fracture second Cervical Vertebra

    Traumatology

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    Fracture 3th Lumbar Vertebra

    Traumatology

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    Fracture 2th Lumbar Vertebra (near to transverse lesion)

    Same patientTraumatology

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    p

    Report after 2 years: no complaints, no limitations

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    Break

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    What to expect?

    - CT in Archeology

    - CT in Cardiology

    - Clinical CT applications: head and neck

    - CT Techniques

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Monday26 march 201209.00 12.00 h

    Thursday29 march 201213.00 16.00 h

    - Dual Energy CT

    - CT Techniques

    Cardiology

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    Fly Through (RCA)

    2002 Sensation-16!

    Cardiac Imaging = need for speed !Cardiology

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    CTA: image quality is inversely proportional to the heartrate

    g g p

    R R R R

    Faster scanning = higher temporal (time) resolution

    Two possibilities:decrease scantime or the heart rate (> 70 bpm beta-blockers)

    - Rotationtime of 500, 420, 370 up to 270 ms (limitation by G-forces)

    - Half-scan reconstruction (180 degrees): 250, 210, 185 up to 135 ms

    Aquisition methodes for CTA in SSCT or DSCTCardiology

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    Applications: Coronary Arteries, Cardiac Function, Valves, Bypass

    q

    1. Spiral (retrospective, with ECG-pulsing)

    - Classic method for CTA (all vendors)

    Advantage:- Phase shifting possible (with wide pulsing)

    - More phases to use in Cardiac Function

    Disadvantage:- Radiation dose between 8-15 mSv (or even higher)

    Multislice Spiral Single Source CT

    Cardiology

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    Image data

    DelayReco

    n

    Reco

    n

    Reco

    nReco

    n

    Continuous

    spiralsc

    an&feed

    z

    -Position

    Time Half scan segment

    Raw Data plus recorded ECG-signal (retrospective reconstruction).

    Reconstruction: delay in percentage or time in msec (e.g. start at 75 %).

    p g

    180 degreesreconstruction

    Siemens

    Multislice Spiral Single Source CTCardiology

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    Time

    Volume Gaps

    Delay

    Reco

    n

    Reco

    n

    Reco

    n

    Reco

    nContinu

    ous

    Spiral

    Scan&

    Feed

    z

    -Position

    Very low heartrate or table feed (pitch) to high: gaps!

    Half scan segment

    180 degreesreconstruction

    Siemens

    Cardiology

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    Gaps in a 16-slice CT

    Single Source CT

    Cardiology

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    Single Source CT

    Temporal resolution of maximum 165 ms

    = 165 msRotation Time

    2

    Temporal Resolution =

    Single Source CT 180 degrees recon

    Cardiology

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    Single Source CT 180 degrees recon

    Technical challenge with high heart rates

    60 bpm 100 bpm

    Comparison between Single Source and Dual Source CTCardiology

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    Siemens SomatomSensation-64 Cardiac(Single Source)

    Siemens Somatom Definition(Dual Source)

    Cardio-imaging: high temporal- and spatial resolution

    Dual Source CT: principle

    Cardiology

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    Dual Source CT: principle

    Normaly only 1 tube (Source) is used for scanning (A-tube, Single Source)

    Dual Source CT

    Cardiology

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    Dual Source CT

    Heart rate independent temp. resolution of 83 ms

    = 83 msRotation Time

    4

    Temporal Resolution =

    Dual Source CT

    Cardiology

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    Dual Source CT

    Reliable imaging of all heart rates

    60 bpm 100 bpm

    Aquisition methodes for CTA in SSCT or DSCTCardiology

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    move move move

    Applications: Non-Coronary (e.g. RF Ablatio), Calcium Scoring

    2. Sequential (prospective, step and shoot)

    - Alternative method (reducing radiation)

    Advantage: radiation dose between 2-4 mSv- Calcium Scoring between 0.8 and 1.5 mSv

    Disadvantage: no phase shifting possible,- only in future Cardiac Function possible- sometimes steps between slices

    Prospective Sequential (Step and Shoot)Cardiology

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    1 2 21

    + =

    - Sometimes steps between slices

    - Higher heartrate: bigger and more

    steps

    - Use betablockers to decreaseheartrate and steps

    Prospective Sequential (Step and Shoot)Cardiology

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    - Sometimes steps between slices

    - Higher heartrate: bigger and more

    steps

    - Use betablockers to decreaseheartrate and steps

    Timing of contrastCardiology

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    Test bolus

    Bolus tracking manual

    - place of ROI:outside the patient in air or fat

    Standardised automatic BolusTracking

    - place of ROI:Descending AortaThreshold 100 HU

    Advantage:less movement, less artefactscompared to Ascending Aorta,operator independent

    manual

    2 cm below the bifurcation of the trachea

    Cardiac contrast protocols (UMCG)Cardiology

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    Contrast: Iomeron 400

    Injector: MedRad Stellant, Sensation-16 and Sensation-64

    Contrast Saline (NaCl)

    ml/sec ml ml/sec ml

    Cardiac spiral 3 3

    and sequential 5 80

    Biphasic 4 20 4 50

    Cardiac-bypass 3 3

    Extra series 5 60 4 30

    Contrast: Iomeron 400

    Injector: MedRad Stellant, Dual Source CT

    Contrast Saline (NaCl)

    ml/sec ml ml/sec ml

    Cardiac spiral 3 3

    and sequential 5 65

    Dual Flow 4 80(30-70%) 4 30

    Cardiac-bypass 3 3

    Extra series 5 60 4 30

    Timing of the reconstruction (spiral mode)Cardiology

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    5 %10 %

    15 %20 %25 %

    30 %35 %40 %45 %50 %

    55 %60 %

    65 %70 %75 %

    80 %85 %90 %

    95 %100 %

    Manual or automatic (best phase)

    Start phase 65 % 70 %

    75 % 80 %

    85 bpm > 65-70%

    85 bpm < 30-35%

    CaseCardiology

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    Male, 57 y Chest-Pain on ER > 50% stenosis & complete occlusion RCA

    LCX LAD

    No significant stenosis

    Dual Source CT > CAG > PTA

    Retrospective spiral CTA with ECG-Pulsing30-80% full dose, rest 20% dose

    Start phase reconstruction 70%

    RCA

    Cardiac Function EvaluationCardiology

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    epicardium

    endocardium

    Do not include the pappilary muscles!

    Systolic phase

    Diastolic phase

    - Recommanded: 20 Phase reconstruction

    - 2 mm, index 2 mm (256 matrix if possible)

    CaseCardiology

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    Siemens CirculationEvaluation Program

    Wall thickness ES Wall thicknessED

    Wall thickening Wall motion

    Aorta ValvesCardiology

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    Recommanded:- 20 Phase recon,

    1 mm, index 1 mm (512 matrix)- Kernel medium/sharp- No ECG-pulsing (3-6 mSv)

    What to expect?

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    - CT in Archeology

    - CT in Cardiology

    - Clinical CT applications: head and neck

    - CT Techniques

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Monday26 march 201209.00 12.00 h

    Thursday29 march 201213.00 16.00 h

    - Dual Energy CT

    - CT Techniques

    Dual Energy CTDual Energy

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    Dual Energy is based on the unique energy dependant attenuationprofiles of different sorts of tissue like fat, soft tissue, bone and contrast.

    Dual Energy

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    Thomas Flohr, First performance evaluation of a DSCT; Eur Radiology (2006)

    Dual Energy is based on the unique energy dependant attenuationprofiles of different sorts of tissue like fat, soft tissue, bone and contrast.

    Dual Energy

    Determination stones in kidney

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    Anno Graser MD et all (Mnich-Grosshadern)

    Determination stones in kidney

    Dual Energy

    Determination stones in kidney

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    Uric acid-stones (9%) Calcium oxalate-stones (80%)

    Anno Graser MD et all (Mnich-Grosshadern)

    D t rm nat n st n s n n y

    Dual Energy

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    Bone Subtraction

    Christoph Becker MD et all (Mnich-Grosshadern)

    Evaluation Myocard Perfusion with DE Perfusion CT

    Dual Energy

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    Ischemia

    - Anatomy- Function- Perfusion

    Dual Energy:

    Dual Energy

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    Possible applications

    - detection of inflammation, e.g. in softplaques

    - differentiation between cartilage, tendons and ligaments(traumatology)

    - differentiation between benign and malign nodules, cystsand other abnormalities

    - simply removing of bony structures and calcification by way of subtraction- differentiation in composite of kidneystones

    - virtuel reconstruction of a native series

    Developments in Dual Source CT

    What to expect?

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    - CT in Archeology

    - CT in Cardiology

    - Clinical CT applications: head and neck

    - CT Techniques

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Monday26 march 201209.00 12.00 h

    Thursday29 march 201213.00 16.00 h

    - Dual Energy CT

    - CT Techniques

    Mummie Janus (RMO)

    Archeology

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    AZG

    1973

    Egyptologist Dr. H. te VeldeMedical student T. Valke

    Archeology

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    1998 Mummie Janus

    1998 Mummie JanusArcheology

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    hart

    Archeology

    Unit of Art in Medicine, Manchester;Facial reconstruction made by Denise Smith and Caroline Wilkinson.

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    Unit of Art in Medicine, Manchester;Facial reconstruction made by Denise Smith and Caroline Wilkinson.

    Archeology

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    1 juni 1999 disclosure of the reconstructed head by the actingrepresentative Egyptian ambassador, mr. Ashraf Elkholy.

    Archeology

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    1 juni 1999 disclosure of the reconstructed head by the actingrepresentative Egyptian ambassador, mr. Ashraf Elkholy.

    Archeology

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    Corpse preserved in peat (veenlijk)

    Archeology

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    Meisje van Yde

    Museum-Assen

    M i j Yd

    Archeology

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    Meisje van Yde

    But is it reliable?

    Tarbot

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    END

    Imaging Techniques in Radiology: CT

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    Wim Tukker systeemspecialist CT UMCG

    What to expect?

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    - CT in Archeology

    - CT in Cardiology

    - Clinical CT applications: head and neck

    - CT Techniques

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Monday26 march 201209.00 12.00 h

    Thursday29 march 201213.00 16.00 h

    - Dual Energy CT

    - CT Techniques

    Each individual projection gives acontribution to the eventual

    Image Reconstruction: Backprojection

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    In practise we look more to the pixelsthen to voxels.

    Realise that a pixel is always anaddition of a volume.

    In an other way: a pixel is a 2-dimen-sional display of a 3-dimensionalemeasurement.

    Voxels en pixels.

    Each individual projection gives acontribution to the eventualpicture advancement (beeldopbouw).

    level 40window 400

    level 40window 400

    CT Chest

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    HU: Hounsfieldschale

    level - window

    level 40window 800

    level - 650window 1600

    CT technique Bushberg, page 358

    Daily calibration of the CT

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    CT technique Bushberg, page 356

    Matrix

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    CT technique Bushberg, page 356

    Backprojection: filtered (Kernel)

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    1 pixel (voxel)Matrix in CT: 512x512

    CT technique Page 352 - 355

    Influence Kernel on Sharpness

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    Bushberg, page 352-355

    Influence Kernel on Noise

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    Bushberg, page 352-355

    Spatial resolution

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    10 mm low Kernel (filter) 5 mm low Kernel

    2 mm with a spatial filter (1H)

    CT technique Bushberg, page 352 - 355

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    Effect of the kernel

    CT technique Bushberg, page 352 - 355

    contrast resolution

    (chicken)

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    (bacon rag)

    (steak)

    (chop)

    ( )

    (wood)(stone)

    CT technique Bushberg, page 352 - 355

    spatial resolution

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    CT technique Bushberg, page 352 - 355

    Influence Slice Thickness on Spatial Resolution

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    Partial Volume Effect

    Spatial resolution Contrast resolution

    CT technique

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    smal details

    - interstitial lungtissue- Inner Ear structures- Temporal Mandibulair Joint

    contrast

    - braintissue

    - abdominal organs, liver- bloodvessels, lymphnodes

    method

    - thin slices- higher kV- lower radiationdose- sharp kernel- wide window

    method

    - thicker slices- lower kV- relative higher dose (Alara)- soft kernel- small window

    Bushberg, page 352-355

    What to expect?

    - CT TechniquesMonday

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    - CT in Archeology

    - CT in Cardiology

    - Clinical CT applications: head and neck

    CT Techniques

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Monday26 march 201209.00 12.00 h

    Thursday29 march 201213.00 16.00 h

    - Dual Energy CT

    - CT Techniques

    CT Chest

    Difference between X-Ray and CT Scoutview?

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    Scoutview A.P.

    Fan beam

    projection

    Bushberg, page 330

    Ascending Aorta

    Window level: mediastinum-settingCT Chest

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    Pulmonary Artery

    Superior Vena Cava

    g

    Descending Aorta

    Pleural Effusion

    Bushberg, page 358

    Window-level: lung-setting

    CT Chest

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    Bushberg, page 358

    Lung Metastasis

    CT Chest

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    CT Chest

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    HD

    DiaphragmaticHernia

    Curved MPR

    Bushberg, page 358-360

    Carcinoma of the Oesophagus

    ?

    CT Chest

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    Bushberg, page 358-360

    Gastric tube

    CT Chest

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    Atherosclerosis

    Heavy smoker, 67 y

    Coughing, blood

    CT Chest

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    First visit jan 2005

    Next visit sept 2008

    CT Chest

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    Lung carcinoma with hilair adenopathy (lymphoma)

    VRT (Volume Rendering Technique) usefull or not?CT Chest

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    Virtual scopy: usefull or not?

    CT Chest

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    VirtualScopy

    Future: evaluation long embolia with Dual Energy Perfusion CT

    CT Chest

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    CT Chest

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    Stent control thoracic aneurysm

    Pancreas

    Stomach

    CT Abdomen

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    Superior Mesenteric Artery

    Spleen

    Kidney

    Adrenal

    Diaphagm

    Liver

    Gallstones

    Abdominal anatomy

    Determination of a heamangioma of the LiverCT Abdomen

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    Four fasic Liver CT

    CT Abdomen

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    Protocol living kidney donation

    CT Abdomen

    Evaluation The Urological System: Ureters; Urinary Bladder;

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    Protocol living kidney donation

    Intra-Uterine Device (IUD).

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    Abdominal Aortic Aneurysm

    CT Abdomen

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    CT Trauma

    Polytrauma

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    ATLS trauma-scheme

    X-thorax (chest)X-cervical spine lateralX-pelvis

    CT Trauma

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    X-pelvis

    - clavicula #- ribfractures- trace fluid right- femur #

    Ultra-sound of the abdomen

    - fluid in the chest- fluid around spleen and liver

    CT Trauma

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    CT or Operation Room?

    -> CT!

    CT Trauma

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    - ventral pneumothorax *)

    - heamatothorax, right side

    - multiple ribfractures *) *) Artificial respirating

    CT Abdomen (arterial phase)

    - Rupture of the spleen- Active arterial bleeding- Fluid round the organs

    CT Trauma

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    Operation Room? No!

    CT Trauma Groin; liesstreek

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    DSA (DigitalSubtractionAngiography)

    - Arterialextravasationfollowed byembolisation

    CT trauma

    First take away the lifethreatening situations!

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    DSA

    - Embolisation; glue procedure

    (artificial infarct)

    - Clavicula #

    CT Trauma

    Collateral damage

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    MPR

    (Multi PlanarReconstruction)

    MIP(Maximum IntensityProjection)

    # Cervical 2

    CT Trauma

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    Collateral damage

    Break

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    What to expect?

    - Clinical CT applications: head and neck

    - CT TechniquesMonday26 march 201209.00 12.00 h

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    - CT in Archeology

    - CT in Cardiology

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Thursday29 march 201213.00 16.00 h

    - Dual Energy CT

    - CT Techniques

    S/N

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    165 mAs

    20 mAs 20 mAs

    165 mAs

    Optical Magnification

    Effect mAs on image quality

    CT fysics

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    20 mAs 110 mAs

    Object attenuation

    Radiation-protection in CT: AEC (Automatic Exposure Control)

    Automatic adaption mA (tube current) to the shape (reference

    detectors) of a patient in the XY-axis (up to Sensation-16).

    CT fysics

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    LOW attenuation

    High attenuation

    Scantime in ms0 500 1000 1500 2000 2500

    0.25

    0.50

    0.75

    1.0

    0

    Modulated tube currentlateral

    a.p.

    Round objects, no reduction!

    Thick patients, children

    Bushberg, page 366

    with AECstandard scan

    Radiation-protection in CT: AEC (Automatic Exposure Control)

    CT fysics

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    189mAs, noise = 9.4HU199mAs, noise = 12.9HU

    Bushberg, page 366

    Care Dose 4D

    CT fysics

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    Real-time tube current adaption: up to 66 % dose reduction compared to fixed mA!

    Sensation 64, Dual Source

    Bushberg, page 366

    Optimal image quality, dose adapted to anatomy

    CareDose 4D

    CT fysics

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    55mAs

    130mAs110mAs

    140mAs

    Bushberg, page 366

    Absorbed dose: deposited energy in tissue (mGray)

    Equivalent dose: biological effects in relation to the sort of ionising radiation

    CT fysics

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    (mSv) X-rays = factor 1 (protons = 5, neutrons = 5-20, = 20)

    Effective dose: cumulative weighted organdose (mSv) > cancer risk.

    Effects: stochastic > no borderline, proportional to dose> tumorinduction and genetic damage

    Effects: deterministic > borderline> cataract, infertility, skin damages

    Bushberg, page 362 - 366

    CTDI = Computer Tomography Dose Index

    Step one: calculating absorbed dose in mGray

    CT fysics

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    Bushberg, page 362 - 366

    A measurement for radiation absorption is CTDIw (mGray).CTDIweighted = 1/3 x CTDIcenter + 2/3 CTDIskin.

    D.L.P.

    CT fysics

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    The Dose Length Product says moreabout the total amount of absorbeddose.

    DLP = CTDIw x st x n (multiply)

    st = slicethickness, beamwidth inZ-axis

    n = number of adjusted slices or

    rotations

    Bushberg, page 362 - 366

    CT fysics

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    Bushberg, page 362 - 366

    Effective dose (E) in mSv: radiation risc for the patient

    Definition organdose: average absorbed energy per organ(mGray). E = total organdose (mSievert)

    CT fysics

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    HT = Absorbed organdose x quality factor (1)

    WT= Organ weighted factor (ICRP 60*)

    E = WT x HT

    * International Commission of Radiological Protection

    Bushberg, page 362 - 366

    Nucleair attack onHiroshima 6 aug 1945 andNagasaki 9 aug 1945

    CT fysics

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    Japan: Hiroshima

    Total number of DeathsImmediately: 78.000End 1945: 140.0002004: 237.062

    Table. Numbers of cancer deaths by cancer type andstrength of evidence for a radiation effect.

    ____________________________________________________________________

    Site Total Estimated Evidence for Site Total Estimated Evidence forDeaths Excess Effect Deaths Excess Effect

    Organ sensitivity after the A-bom radiation, Hiroshima(RERF, Radiation Effects Research Foundation)

    CT fysics

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    Deaths Excess Effect Deaths Excess Effect____________________________________________________________________

    Stomach 2529 65 strong F. Breast 211 37 strong

    Lung 939 67 strong Ovary 120 10 strong

    Liver 753 30 strong Bladder 118 10 strong

    Uterus 476 9 moderate Prostate 80 2 weak

    Colon 347 23 strong Bone 32 3 moderate

    Rectum 298 7 weak Other solid 948 47 strong

    Pancreas 297 3 weak Lymphoma 162 1 weak

    Esophagus 234 14 strong Myeloma 51 6 strong

    Gallbladder 228 12 moderate

    Weightfactors for calculation of the

    effective (organ) dose.

    Weight factors: ICRP-norm

    Absorbed dose (mGy) > organdose (mSv)

    CT fysics

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    (ICRP #26, 1977) (ICRP #60, 1990)

    Gonads 0,25 0,20Bone Marrow 0,12 0,12Colon - 0,12Lung 0,12 0,12Stomach - 0,12

    Bladder - 0,05Breast 0,15 0,05Liver - 0,05Oesophagus - 0,05Thyroid 0,03 0,05Skin - 0,01Skeleton 0,03 0,01Remainder 0,30 0,05

    Sum 1,00 1,00

    What to expect?

    - CT in Cardiology

    - Clinical CT applications: head and neck

    - CT TechniquesMonday26 march 201209.00 12.00 h

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    - CT in Archeology

    CT in Cardiology

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Thursday29 march 201213.00 16.00 h

    - Dual Energy CT

    - CT Techniques

    Disadvantages 3D to 2D

    Cone Beam CT

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    NEVER BELIEVE AN X-RAY

    2006

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    NewTom 3G DVT

    i-CAT Cone Beam 3-DImaging System

    A Clear Difference that You Can See!

    ConventionalPanoramic (OPG)

    Imposition of Tissue

    Projection Distortion

    Cone Beam CT

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    NewTom PanoramicCone Beam CT

    No Distortion

    1:1 ScaleExact Measurements

    j

    Magnification Error

    Working of a Cone Beam CT

    Fan-beam of X-ray in CT Cone-beam of X-ray

    Cone Beam CT

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    Working of a Cone Beam CT

    Cone Beam CT

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    LA Feldkamp, LC Davis, JW Kress: Practical cone-beam algorithmJ. Opt. Soc. Am. (1984), 612-619

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    Panoramic ImagesRay Sum ImagesCone Beam CT

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    Unlimited post processing invariable slice thicknessMIP (Maximum Intensity Projection)

    Cone Beam CT

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    Made by a Cone-Beam CT

    Effective doseCone Beam CT

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    Illuma NewTomVG Ewoo Kavo/Icat NewTom Galileos

    137 S 75 S 70 S 68 S 36 S 29 S

    PlanmecaProMax 3DSirona GALILEOS

    Cone Beam CT

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    2010

    NewTom 3G NewTom VG

    What to expect?

    - CT in Cardiology

    - Clinical CT applications: head and neck

    - CT TechniquesMonday26 march 201209.00 12.00 h

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    165/180

    - CT in Archeology

    - Cone Beam CT

    - CT in Forensics (CSI-Groningen)

    - Clinical CT applications: chest and abdomen

    - Radiation dose

    Thursday29 march 201213.00 16.00 h

    - Dual Energy CT

    - CT Techniques

    Forensic Radiology

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    166/180

    Forensic Radiology

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    167/180

    Bicycle versus car; on purpose?

    Shooting

    - How many bullets?- Ballistic trajectory?

    - Cause of death?

    Forensic Radiology

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    ?

    Forensic Radiology Dental identification

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    UMCG

    Exploded Bone Marrow

    Dental identificationForensic Radiology

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    UMCGWe had a match!

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    Mummie Janus (RMO)

    Meisje van Yde (Drents Museum)

    Forensic Radiology

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    http://www.fbi.gov

    Forensic Radiology

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    www.fbi.gov www.marylandmissing.com www.missingpersons.org

    Meisje van NuldeForensic Radiology

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    Meisje van NuldeForensic Radiology

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    175/180

    Meisje van NuldeForensic Radiology

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    Meisje van NuldeForensic Radiology

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    RowenaRochelle

    Forensic Radiology

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    Thanks to ultra sound specialist: Jan Visscher

    Mouse !!!

    Forensic Radiology

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    Last Dinner ???

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